Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | cell polarity protein | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Echinococcus multilocularis | fibropellin Ia | 0.006 | 0.0332 | 0.0332 |
Echinococcus granulosus | fibropellin Ia | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0065 | 0.0479 | 0.1162 |
Schistosoma mansoni | Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] | 0.006 | 0.0332 | 0.0332 |
Schistosoma mansoni | notch | 0.006 | 0.0332 | 0.0332 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0049 | 0 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0187 | 0.4118 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Brugia malayi | EGF-like domain containing protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus granulosus | neurogenic locus notch protein | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | jmjC domain containing protein | 0.0065 | 0.0479 | 0.1162 |
Brugia malayi | Muscleblind-like protein | 0.0166 | 0.3487 | 0.8468 |
Brugia malayi | EGF-like domain containing protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus granulosus | protein jagged 2 | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | EGF-like domain containing protein | 0.006 | 0.0332 | 0.0806 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0 | 0.5 |
Brugia malayi | Delta serrate ligand family protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus granulosus | protein jagged 1 | 0.006 | 0.0332 | 0.0332 |
Schistosoma mansoni | lipoxygenase | 0.0383 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0443 | 0.0443 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.0332 | 0.0332 |
Schistosoma mansoni | rab6-interacting | 0.0064 | 0.0443 | 0.0443 |
Echinococcus granulosus | neurogenic locus protein delta | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | Animal haem peroxidase family protein | 0.0187 | 0.4118 | 1 |
Echinococcus multilocularis | muscleblind protein | 0.0166 | 0.3487 | 0.3487 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0187 | 0.4118 | 1 |
Echinococcus multilocularis | RUN | 0.0064 | 0.0443 | 0.0443 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0049 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0064 | 0.0443 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.006 | 0.0332 | 0.0806 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Toxoplasma gondii | EGF family domain-containing protein | 0.006 | 0.0332 | 1 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | notch protein | 0.006 | 0.0332 | 0.0806 |
Brugia malayi | Muscle positioning protein 4 | 0.006 | 0.0332 | 0.0806 |
Echinococcus granulosus | notch | 0.006 | 0.0332 | 0.0332 |
Schistosoma mansoni | notch | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0049 | 0 | 0.5 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0049 | 0 | 0.5 |
Brugia malayi | EGF-like domain containing protein | 0.006 | 0.0332 | 0.0806 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.0332 | 0.0332 |
Onchocerca volvulus | 0.0064 | 0.0443 | 0.0294 | |
Echinococcus multilocularis | muscleblind protein 1 | 0.0166 | 0.3487 | 0.3487 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0383 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0064 | 0.0443 | 0.0443 |
Brugia malayi | EGF-like domain containing protein | 0.006 | 0.0332 | 0.0806 |
Brugia malayi | EGF-like domain containing protein | 0.006 | 0.0332 | 0.0806 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.3487 | 0.8468 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Brugia malayi | Animal haem peroxidase family protein | 0.0187 | 0.4118 | 1 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0049 | 0 | 0.5 |
Schistosoma mansoni | loxhd1 | 0.0064 | 0.0443 | 0.0443 |
Brugia malayi | hypothetical protein | 0.0064 | 0.0443 | 0.1076 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | hypothetical protein | 0.0187 | 0.4118 | 1 |
Schistosoma mansoni | peroxidasin | 0.0187 | 0.4118 | 0.4118 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.0332 | 0.0332 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0065 | 0.0479 | 0.0479 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Giardia lamblia | High cysteine protein | 0.006 | 0.0332 | 1 |
Echinococcus multilocularis | protein jagged 1 | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Onchocerca volvulus | Peroxidase homolog | 0.0187 | 0.4118 | 1 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0065 | 0.0479 | 0.0479 |
Schistosoma mansoni | jumonji domain containing protein | 0.0065 | 0.0479 | 0.0479 |
Brugia malayi | Peroxidasin | 0.0187 | 0.4118 | 1 |
Brugia malayi | GCC2 and GCC3 family protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.006 | 0.0332 | 0.0332 |
Echinococcus multilocularis | neural cadherin | 0.006 | 0.0332 | 0.0332 |
Echinococcus granulosus | protein jagged 2 | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Echinococcus granulosus | delta-like protein 1 | 0.006 | 0.0332 | 0.0332 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0065 | 0.0479 | 0.0479 |
Schistosoma mansoni | notch | 0.006 | 0.0332 | 0.0332 |
Echinococcus granulosus | neurogenic locus notch protein | 0.006 | 0.0332 | 0.0332 |
Onchocerca volvulus | 0.0187 | 0.4118 | 1 | |
Echinococcus granulosus | protein jagged 1 | 0.006 | 0.0332 | 0.0332 |
Onchocerca volvulus | Peroxidasin homolog | 0.0187 | 0.4118 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0064 | 0.0443 | 0.0443 |
Echinococcus multilocularis | neurogenic locus notch protein 4 | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0187 | 0.4118 | 1 |
Schistosoma mansoni | notch | 0.006 | 0.0332 | 0.0332 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0064 | 0.0443 | 0.5 |
Schistosoma mansoni | polycystin 1-related | 0.0064 | 0.0443 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Schistosoma mansoni | laminin gamma-3 chain | 0.006 | 0.0332 | 0.0332 |
Onchocerca volvulus | 0.0064 | 0.0443 | 0.0294 | |
Onchocerca volvulus | Peroxidasin homolog | 0.0187 | 0.4118 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0049 | 0 | 0.5 |
Schistosoma mansoni | rab6-interacting | 0.0064 | 0.0443 | 0.0443 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | Animal haem peroxidase family protein | 0.0187 | 0.4118 | 1 |
Echinococcus multilocularis | protein jagged 1 | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0187 | 0.4118 | 1 |
Echinococcus multilocularis | notch | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus granulosus | RUN | 0.0064 | 0.0443 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus granulosus | slit 2 protein | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | Doublecortin family protein | 0.0064 | 0.0443 | 0.1076 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.006 | 0.0332 | 0.0332 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0064 | 0.0443 | 0.0443 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Schistosoma mansoni | septate junction protein | 0.006 | 0.0332 | 0.0332 |
Echinococcus granulosus | neurogenic locus notch protein 4 | 0.006 | 0.0332 | 0.0332 |
Onchocerca volvulus | Peroxidase homolog | 0.0187 | 0.4118 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0065 | 0.0479 | 0.1162 |
Brugia malayi | Blistered cuticle protein 3 | 0.0187 | 0.4118 | 1 |
Loa Loa (eye worm) | Notch2 | 0.006 | 0.0332 | 0.0806 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0065 | 0.0479 | 0.0479 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0187 | 0.4118 | 1 |
Echinococcus granulosus | peroxidasin | 0.0187 | 0.4118 | 0.4118 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0065 | 0.0479 | 0.0479 |
Echinococcus multilocularis | protein jagged 2 | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Onchocerca volvulus | 0.0187 | 0.4118 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Schistosoma mansoni | lipoxygenase | 0.0268 | 0.6547 | 0.6547 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0187 | 0.4118 | 1 |
Loa Loa (eye worm) | doublecortin family protein | 0.0064 | 0.0443 | 0.1076 |
Onchocerca volvulus | 0.0187 | 0.4118 | 1 | |
Brugia malayi | EGF-like domain containing protein | 0.006 | 0.0332 | 0.0806 |
Schistosoma mansoni | slit | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Brugia malayi | notch-like transmembrane receptor | 0.006 | 0.0332 | 0.0806 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0064 | 0.0443 | 0.0443 |
Echinococcus multilocularis | slit 2 protein | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | Cadherin domain containing protein | 0.006 | 0.0332 | 0.0806 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Schistosoma mansoni | peroxidasin | 0.0187 | 0.4118 | 0.4118 |
Trypanosoma brucei | protein kinase, putative | 0.0049 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0064 | 0.0443 | 0.0443 |
Onchocerca volvulus | Dual oxidase homolog | 0.0187 | 0.4118 | 1 |
Echinococcus multilocularis | peroxidasin | 0.0187 | 0.4118 | 0.4118 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0064 | 0.0443 | 0.5 |
Echinococcus multilocularis | fat cadherin tumor suppressor | 0.006 | 0.0332 | 0.0332 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0 | 0.5 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0065 | 0.0479 | 0.0479 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0187 | 0.4118 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0443 | 0.1076 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0049 | 0 | 0.5 |
Brugia malayi | Cadherin domain containing protein | 0.006 | 0.0332 | 0.0806 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.3487 | 0.8468 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0443 | 0.1076 |
Echinococcus granulosus | muscleblind protein | 0.0166 | 0.3487 | 0.3487 |
Schistosoma mansoni | notch | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Brugia malayi | Transmembrane cell adhesion receptor mua-3 precursor, putative | 0.006 | 0.0332 | 0.0806 |
Brugia malayi | Animal haem peroxidase family protein | 0.0187 | 0.4118 | 1 |
Schistosoma mansoni | notch | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus granulosus | neural cadherin | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | hypothetical protein | 0.0064 | 0.0443 | 0.1076 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.