Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | sodium channel, voltage-gated, type IX, alpha subunit | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.008 | 0.6684 | 0.6684 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.008 | 0.6684 | 0.6684 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.008 | 0.6684 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.008 | 0.6684 | 0.8058 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.008 | 0.6684 | 1 |
Brugia malayi | ecdysteroid receptor | 0.008 | 0.6684 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.008 | 0.6684 | 0.6684 |
Loa Loa (eye worm) | MaxiK calcium-activated potassium channel | 0.0064 | 0.3784 | 0.4562 |
Echinococcus multilocularis | calcium activated potassium channel variant | 0.0089 | 0.8295 | 0.8295 |
Echinococcus granulosus | calcium activated potassium channel variant | 0.0089 | 0.8295 | 0.8295 |
Loa Loa (eye worm) | large conductance calcium-activated potassium channel alpha subunit ai | 0.0089 | 0.8295 | 1 |
Echinococcus granulosus | potassium large conductance calcium activated | 0.0099 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.008 | 0.6684 | 0.8058 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.008 | 0.6684 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.008 | 0.6684 | 0.6684 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.008 | 0.6684 | 0.6684 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.6684 | 0.8058 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.3784 | 0.4562 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.008 | 0.6684 | 0.6684 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.008 | 0.6684 | 0.6684 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.6684 | 0.8058 |
Echinococcus granulosus | FTZ F1 alpha | 0.008 | 0.6684 | 0.6684 |
Brugia malayi | Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog | 0.0064 | 0.3784 | 0.5662 |
Echinococcus multilocularis | potassium large conductance calcium activated | 0.0099 | 1 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.008 | 0.6684 | 0.6684 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.008 | 0.6684 | 0.8058 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.008 | 0.6684 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.008 | 0.6684 | 0.6684 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.008 | 0.6684 | 0.6684 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.008 | 0.6684 | 0.8058 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.008 | 0.6684 | 0.6684 |
Schistosoma mansoni | coup transcription factor | 0.008 | 0.6684 | 0.6684 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.008 | 0.6684 | 0.8058 |
Schistosoma mansoni | nuclear hormone receptor | 0.008 | 0.6684 | 0.6684 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.6684 | 0.8058 |
Onchocerca volvulus | Bile acid receptor homolog | 0.008 | 0.6684 | 0.5 |
Echinococcus granulosus | voltage gated sodium channel Nav1 alpha subunit | 0.0052 | 0.1698 | 0.1698 |
Echinococcus multilocularis | calcium activated potassium channel | 0.0099 | 1 | 1 |
Leishmania major | calcium channel protein, putative,ion transporter, putative | 0.0052 | 0.1698 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.008 | 0.6684 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.008 | 0.6684 | 1 |
Brugia malayi | nuclear hormone receptor | 0.008 | 0.6684 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.008 | 0.6684 | 0.6684 |
Schistosoma mansoni | thyroid hormone receptor | 0.008 | 0.6684 | 0.6684 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.008 | 0.6684 | 0.6684 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.6684 | 0.8058 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.6684 | 0.8058 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.008 | 0.6684 | 0.6684 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.6684 | 0.8058 |
Onchocerca volvulus | 0.008 | 0.6684 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.6684 | 0.8058 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.008 | 0.6684 | 1 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0099 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.008 | 0.6684 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.008 | 0.6684 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.008 | 0.6684 | 1 |
Echinococcus granulosus | sodium channel protein | 0.0052 | 0.1698 | 0.1698 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.008 | 0.6684 | 0.6684 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0089 | 0.8295 | 0.8295 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.008 | 0.6684 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.008 | 0.6684 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.008 | 0.6684 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.008 | 0.6684 | 0.8058 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.008 | 0.6684 | 0.6684 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.008 | 0.6684 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.008 | 0.6684 | 0.6684 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.008 | 0.6684 | 0.6684 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.008 | 0.6684 | 0.8058 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.008 | 0.6684 | 0.6684 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.008 | 0.6684 | 0.8058 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.008 | 0.6684 | 0.6684 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.008 | 0.6684 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.008 | 0.6684 | 0.6684 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.6684 | 0.8058 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.008 | 0.6684 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.008 | 0.6684 | 0.6684 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.008 | 0.6684 | 0.6684 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.008 | 0.6684 | 0.6684 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.008 | 0.6684 | 0.6684 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.008 | 0.6684 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.008 | 0.6684 | 1 |
Brugia malayi | steroid hormone receptor | 0.008 | 0.6684 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.008 | 0.6684 | 0.6684 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.008 | 0.6684 | 0.5 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.008 | 0.6684 | 0.6684 |
Echinococcus multilocularis | sodium channel protein | 0.0052 | 0.1698 | 0.1698 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.