Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.001 | 0.0039 | 0.0013 | |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0039 |
Schistosoma mansoni | coup transcription factor | 0.0021 | 0.0185 | 0.0275 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0054 | 0.0054 |
Schistosoma mansoni | tyrosine kinase | 0.0208 | 0.2714 | 0.4034 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0201 | 0.0201 |
Echinococcus multilocularis | mothers against decapentaplegic 6 | 0.0011 | 0.0057 | 0.0084 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0039 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0129 | 0.0192 |
Schistosoma mansoni | nuclear receptor | 0.001 | 0.0039 | 0.0058 |
Schistosoma mansoni | hypothetical protein | 0.0095 | 0.1194 | 0.1774 |
Brugia malayi | Guanine nucleotide-binding protein alpha-6 subunit, putative | 0.0022 | 0.0201 | 0.0201 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0103 | 0.1305 | 0.194 |
Echinococcus granulosus | guanine nucleotide binding protein subunit | 0.0022 | 0.0201 | 0.0299 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0021 | 0.0185 | 0.0185 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0021 | 0.0185 | 0.0185 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0021 | 0.0185 | 0.0275 |
Echinococcus granulosus | paired box gene 3/7 (eyeless, eyegone, twin of eyeless) | 0.0014 | 0.0101 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0185 | 0.0185 |
Schistosoma mansoni | zinc finger protein | 0.001 | 0.0039 | 0.0058 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.0185 | 0.0275 |
Loa Loa (eye worm) | DIX domain-containing protein | 0.0009 | 0.0026 | 0.0026 |
Brugia malayi | MH2 domain containing protein | 0.0361 | 0.4786 | 0.4786 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0949 | 0.5 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.001 | 0.0039 | 0.0058 |
Trichomonas vaginalis | GTP-binding protein alpha subunit, gna, putative | 0.0022 | 0.0201 | 0.5 |
Brugia malayi | MH2 domain containing protein | 0.0025 | 0.024 | 0.024 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0021 | 0.0185 | 0.0185 |
Schistosoma mansoni | GTP-binding protein (I) alpha subunit gnai | 0.0022 | 0.0201 | 0.0299 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0051 | 0.059 | 0.4744 |
Onchocerca volvulus | 0.001 | 0.0039 | 0.0013 | |
Echinococcus multilocularis | GPCR, family 2 | 0.0095 | 0.1194 | 0.1774 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0988 | 0.0988 |
Schistosoma mansoni | nuclear receptor | 0.001 | 0.0039 | 0.0058 |
Brugia malayi | ecdysteroid receptor | 0.0021 | 0.0185 | 0.0185 |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.024 | 0.0357 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0206 | 0.2686 | 0.2686 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.0185 | 0.0275 |
Brugia malayi | N-terminal motif family protein | 0.0009 | 0.0024 | 0.0024 |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.024 | 0.0357 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0095 | 0.1194 | 0.1774 |
Schistosoma mansoni | smad | 0.0011 | 0.0057 | 0.0084 |
Brugia malayi | hypothetical protein | 0.001 | 0.0039 | 0.0039 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0021 | 0.0185 | 0.0185 |
Schistosoma mansoni | hypothetical protein | 0.0206 | 0.2686 | 0.3993 |
Onchocerca volvulus | Mothers against decapentaplegic homolog | 0.0011 | 0.0057 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0201 | 0.0201 |
Brugia malayi | MH1 domain containing protein | 0.0014 | 0.0092 | 0.0092 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.0129 | 0.0129 |
Schistosoma mansoni | GTP-binding protein alpha subunit | 0.0022 | 0.0201 | 0.0299 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.0185 | 0.0275 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0949 | 0.5 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0009 | 0.0026 | 0.0038 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0025 | 0.024 | 0.0357 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0026 | 0.0026 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0249 | 0.1467 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.001 | 0.0039 | 0.0058 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.0011 | 0.0057 | 0.0057 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.001 | 0.0039 | 0.0039 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0201 | 0.0201 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0021 | 0.0185 | 0.016 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0101 | 0.0101 |
Echinococcus multilocularis | Pleckstrin G protein, interacting region | 0.0009 | 0.0026 | 0.0038 |
Schistosoma mansoni | GTP-binding protein (I) alpha-2 subunit gnai2 | 0.0022 | 0.0201 | 0.0299 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0027 | 0.0267 | 0.1677 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0026 | 0.0026 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.0185 | 0.0275 |
Echinococcus granulosus | mothers against decapentaplegic 6 | 0.0011 | 0.0057 | 0.0084 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.0185 | 0.0275 |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.024 | 0.0357 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0026 | 0.0026 |
Echinococcus multilocularis | Smad4 | 0.0025 | 0.024 | 0.0357 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0185 | 0.0185 |
Loa Loa (eye worm) | GTP-binding regulatory protein alpha chain | 0.0022 | 0.0201 | 0.0201 |
Onchocerca volvulus | 0.0747 | 1 | 1 | |
Brugia malayi | nuclear receptor NHR-88 | 0.0021 | 0.0185 | 0.0185 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0201 | 0.0201 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0949 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.1305 | 0.1305 |
Echinococcus granulosus | guanine nucleotide binding protein subunit | 0.0022 | 0.0201 | 0.0299 |
Schistosoma mansoni | GTP-binding protein (I) alpha-1subunit gnai1 | 0.0022 | 0.0201 | 0.0299 |
Brugia malayi | steroid hormone receptor | 0.0021 | 0.0185 | 0.0185 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0095 | 0.1194 | 0.1774 |
Loa Loa (eye worm) | RasGEF domain-containing protein | 0.0009 | 0.0024 | 0.0024 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0077 | 0.0949 | 1 |
Onchocerca volvulus | 0.0022 | 0.0201 | 0.0176 | |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0077 | 0.0949 | 0.1411 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0249 | 0.0249 |
Schistosoma mansoni | Smad4 | 0.0011 | 0.0057 | 0.0084 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0185 | 0.0185 |
Schistosoma mansoni | nuclear hormone receptor | 0.0021 | 0.0185 | 0.0275 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0039 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0095 | 0.1194 | 0.1194 |
Echinococcus multilocularis | mothers against decapentaplegic 2 | 0.0011 | 0.0057 | 0.0084 |
Echinococcus granulosus | mothers against decapentaplegic 2 | 0.0011 | 0.0057 | 0.0084 |
Onchocerca volvulus | 0.0157 | 0.2023 | 0.2003 | |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0051 | 0.059 | 0.0878 |
Schistosoma mansoni | smad | 0.0025 | 0.024 | 0.0357 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0021 | 0.0185 | 0.0185 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0011 | 0.0061 | 0.0091 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0054 | 0.0054 |
Echinococcus granulosus | Pleckstrin G protein interacting region | 0.0009 | 0.0026 | 0.0038 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0021 | 0.0185 | 0.0185 |
Echinococcus granulosus | smad | 0.0025 | 0.024 | 0.0357 |
Brugia malayi | G-protein alpha subunit | 0.0022 | 0.0201 | 0.0201 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0039 | 0.0039 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.0185 | 0.0185 |
Loa Loa (eye worm) | vab-3 | 0.0014 | 0.0101 | 0.0101 |
Echinococcus multilocularis | gtp binding protein (I) alpha 1subunit | 0.0022 | 0.0201 | 0.0299 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0021 | 0.0185 | 0.0185 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0021 | 0.0185 | 0.0185 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0021 | 0.0185 | 0.0275 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.0129 | 0.0192 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.001 | 0.0039 | 0.0058 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1194 | 0.1194 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.0185 | 0.0185 |
Echinococcus multilocularis | guanine nucleotide binding protein (G protein) | 0.0022 | 0.0201 | 0.0299 |
Trichomonas vaginalis | GTP-binding protein (q) alpha-11 subunit, gna11, putative | 0.0022 | 0.0201 | 0.5 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0051 | 0.059 | 0.0878 |
Schistosoma mansoni | GTP-binding protein alpha subunit | 0.0022 | 0.0201 | 0.0299 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0021 | 0.0185 | 0.0275 |
Onchocerca volvulus | 0.0022 | 0.0201 | 0.0176 | |
Brugia malayi | guanine nucleotide-binding protein G-o protein alpha subunit | 0.0022 | 0.0201 | 0.0201 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.001 | 0.0039 | 0.0058 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.0185 | 0.0275 |
Echinococcus multilocularis | expressed protein | 0.0022 | 0.0201 | 0.0299 |
Brugia malayi | N-terminal motif family protein | 0.0177 | 0.2302 | 0.2302 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0009 | 0.0026 | 0.0038 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.0744 | 0.0744 |
Schistosoma mansoni | GTP-binding protein (q) alpha-11 subunit gna11 | 0.0022 | 0.0201 | 0.0299 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0301 | 0.3972 | 0.3972 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.1028 | 0.1528 |
Brugia malayi | guanine nucleotide-binding protein G(o), alpha subunit, putative | 0.0022 | 0.0201 | 0.0201 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0949 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein G protein | 0.0022 | 0.0201 | 0.0299 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0128 | 0.1634 | 0.1634 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0009 | 0.0026 | 0.0038 |
Brugia malayi | Probable ClpP-like protease | 0.0077 | 0.0949 | 0.0949 |
Loa Loa (eye worm) | guanine nucleotide-binding protein alpha-6 subunit | 0.0022 | 0.0201 | 0.0201 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0021 | 0.0185 | 0.0185 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0021 | 0.0185 | 0.0275 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0249 | 0.0249 |
Brugia malayi | MH1 domain containing protein | 0.0025 | 0.024 | 0.024 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0024 | 0.0024 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.001 | 0.0039 | 0.0058 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.0129 | 0.1119 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0086 | 0.1068 | 0.1068 |
Echinococcus granulosus | paired box protein pax 1 | 0.0014 | 0.0101 | 0.0151 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0103 | 0.1305 | 0.194 |
Brugia malayi | 'Paired box' domain containing protein | 0.0014 | 0.0101 | 0.0101 |
Echinococcus granulosus | GPCR family 2 | 0.0095 | 0.1194 | 0.1774 |
Brugia malayi | guanine nucleotide-binding protein alpha-7 subunit, putative | 0.0022 | 0.0201 | 0.0201 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0054 | 0.0054 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0009 | 0.0026 | 0.0026 |
Echinococcus multilocularis | paired box protein pax 6 | 0.0014 | 0.0101 | 0.0151 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0021 | 0.0185 | 0.0185 |
Schistosoma mansoni | dep domain containing protein | 0.0009 | 0.0026 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0039 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0021 | 0.0185 | 0.0185 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0039 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0021 | 0.0185 | 0.016 |
Brugia malayi | conserved hypotetical protein | 0.001 | 0.0039 | 0.0039 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0039 | 0.0058 |
Brugia malayi | Guanine nucleotide-binding protein alpha-3 subunit, putative | 0.0022 | 0.0201 | 0.0201 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0185 | 0.0185 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0021 | 0.0185 | 0.0275 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0011 | 0.0054 | 0.0081 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.0129 | 0.0192 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0185 | 0.0185 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0009 | 0.0026 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0039 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0025 | 0.024 | 0.0357 |
Brugia malayi | Gooseberry protein | 0.0014 | 0.0101 | 0.0101 |
Echinococcus multilocularis | smad | 0.0025 | 0.024 | 0.0357 |
Echinococcus multilocularis | tyrosine protein kinase ABL1 | 0.0211 | 0.2754 | 0.4095 |
Echinococcus multilocularis | paired box protein pax 6 | 0.0014 | 0.0101 | 0.0151 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.001 | 0.0039 | 0.0039 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0077 | 0.0949 | 1 |
Echinococcus granulosus | Smad4 | 0.0025 | 0.024 | 0.0357 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0101 | 0.0101 |
Loa Loa (eye worm) | G protein alpha subunit 3 | 0.0022 | 0.0201 | 0.0201 |
Trichomonas vaginalis | GTP-binding protein alpha subunit, gna, putative | 0.0022 | 0.0201 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0092 | 0.0092 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.001 | 0.0039 | 0.0058 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0021 | 0.0185 | 0.0275 |
Schistosoma mansoni | paired box protein pax-6 | 0.0014 | 0.0101 | 0.0151 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0949 | 1 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0949 | 0.5 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0054 | 0.0054 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0129 | 0.0192 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0021 | 0.0185 | 0.016 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.001 | 0.0039 | 0.0013 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.001 | 0.0039 | 0.0039 |
Echinococcus multilocularis | guanine nucleotide binding protein (G protein) | 0.0022 | 0.0201 | 0.0299 |
Schistosoma mansoni | GTP-binding protein (I) alpha-1subunit gnai1 | 0.0022 | 0.0201 | 0.0299 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0505 | 0.6727 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0505 | 0.6727 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0185 | 0.0185 |
Onchocerca volvulus | 0.0014 | 0.0101 | 0.0076 | |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.001 | 0.0039 | 0.0013 |
Schistosoma mansoni | dishevelled | 0.0009 | 0.0026 | 0.0038 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0027 | 0.0267 | 0.1677 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0101 | 0.0101 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0021 | 0.0185 | 0.0185 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0249 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0039 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0249 | 0.1467 |
Schistosoma mansoni | fyve finger-containing phosphoinositide kinase fyv1 | 0.0009 | 0.0026 | 0.0038 |
Echinococcus multilocularis | guanine nucleotide binding protein subunit | 0.0022 | 0.0201 | 0.0299 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0249 | 1 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0039 | 0.0039 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0011 | 0.0054 | 0.0054 |
Schistosoma mansoni | paired box protein pax-6 | 0.0014 | 0.0101 | 0.0151 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0021 | 0.0185 | 0.0185 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0011 | 0.0057 | 0.0057 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.2023 | 0.2023 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0011 | 0.0057 | 0.0057 |
Loa Loa (eye worm) | heterotrimeric G protein alpha subunit | 0.0022 | 0.0201 | 0.0201 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0129 | 0.0192 |
Echinococcus granulosus | expressed protein | 0.0022 | 0.0201 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0054 | 0.0054 |
Onchocerca volvulus | 0.0022 | 0.0201 | 0.0176 | |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0103 | 0.1305 | 0.1305 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0054 | 0.0054 |
Brugia malayi | Nuclear hormone receptor E75 | 0.001 | 0.0039 | 0.0039 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0039 | 0.0058 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0249 | 0.2422 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.001 | 0.0039 | 0.0039 |
Brugia malayi | DIX domain containing protein | 0.0009 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0025 | 0.024 | 0.024 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0095 | 0.1194 | 0.1194 |
Echinococcus multilocularis | paired box protein pax 6 | 0.0014 | 0.0101 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0057 | 0.0057 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.0744 | 0.0744 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0009 | 0.0026 | 0.0038 |
Schistosoma mansoni | GTP-binding protein (q) alpha-11 subunit gna11 | 0.0022 | 0.0201 | 0.0299 |
Schistosoma mansoni | Smad4 | 0.0011 | 0.0057 | 0.0084 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0744 | 0.1106 |
Schistosoma mansoni | GTP-binding protein (I) alpha-2 subunit gnai2 | 0.0022 | 0.0201 | 0.0299 |
Trichomonas vaginalis | GTP-binding protein (O) alpha subunit, gnao, putative | 0.0022 | 0.0201 | 0.5 |
Brugia malayi | nuclear receptor RXR | 0.0011 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0021 | 0.0185 | 0.0185 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0095 | 0.1194 | 0.1194 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0249 | 1 |
Schistosoma mansoni | GTP-binding protein alpha subunit gna | 0.0022 | 0.0201 | 0.0299 |
Loa Loa (eye worm) | pax transcription factor protein 2 | 0.0747 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0039 |
Brugia malayi | paired box protein | 0.0014 | 0.0101 | 0.0101 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0949 | 0.0949 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0744 | 0.1106 |
Loa Loa (eye worm) | Smad1 | 0.0025 | 0.024 | 0.024 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.001 | 0.0039 | 0.0058 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.001 | 0.0039 | 0.0058 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0025 | 0.024 | 0.024 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0039 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0249 | 0.1467 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0061 | 0.0091 |
Brugia malayi | MH1 domain containing protein | 0.0014 | 0.0092 | 0.0092 |
Brugia malayi | MH1 domain containing protein | 0.0025 | 0.024 | 0.024 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0051 | 0.059 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0027 | 0.0267 | 0.2609 |
Schistosoma mansoni | paired box protein pax-6 | 0.0014 | 0.0101 | 0.0151 |
Echinococcus granulosus | gtp binding protein I alpha 1subunit | 0.0022 | 0.0201 | 0.0299 |
Brugia malayi | RNA binding protein | 0.0062 | 0.0744 | 0.0744 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0101 | 0.0101 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.001 | 0.0039 | 0.0039 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.001 | 0.0039 | 0.0058 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0301 | 0.3972 | 0.3972 |
Loa Loa (eye worm) | nuclear factor I | 0.0014 | 0.0092 | 0.0092 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.0129 | 0.0129 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.3972 | 0.3972 |
Brugia malayi | guanine nucleotide-binding protein alpha-3 subunit, putative | 0.0022 | 0.0201 | 0.0201 |
Onchocerca volvulus | 0.0014 | 0.0101 | 0.0076 | |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.0744 | 0.1106 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.0185 | 0.0185 |
Trichomonas vaginalis | GTP-binding protein (z) alpha subunit, gnaz, putative | 0.0022 | 0.0201 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0095 | 0.1194 | 0.1774 |
Brugia malayi | paired box pox-meso protein | 0.0014 | 0.0101 | 0.0101 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0.0185 | 0.0275 |
Brugia malayi | hypothetical protein | 0.001 | 0.0039 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0201 | 0.0201 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0009 | 0.0026 | 0.0026 |
Echinococcus granulosus | guanine nucleotide binding protein G protein | 0.0022 | 0.0201 | 0.0299 |
Echinococcus granulosus | paired box protein pax 6 | 0.0014 | 0.0101 | 0.0151 |
Brugia malayi | Guanine nucleotide-binding protein alpha-12 subunit, putative | 0.0022 | 0.0201 | 0.0201 |
Schistosoma mansoni | Smad4 | 0.0025 | 0.024 | 0.0357 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0039 | 0.0058 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0021 | 0.0185 | 0.0275 |
Schistosoma mansoni | GTP-binding protein (I) alpha-2 subunit gnai2 | 0.0022 | 0.0201 | 0.0299 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0505 | 0.6727 | 0.6727 |
Echinococcus granulosus | paired box protein pax 6 | 0.0014 | 0.0101 | 0.0151 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0086 | 0.1068 | 0.1588 |
Brugia malayi | GTP-binding regulatory protein alpha chain - starfish, putative | 0.0022 | 0.0201 | 0.0201 |
Brugia malayi | 'Paired box' domain containing protein | 0.0014 | 0.0101 | 0.0101 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0021 | 0.0185 | 0.0185 |
Schistosoma mansoni | paired box protein pax-1-related | 0.0014 | 0.0101 | 0.0151 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0.0185 | 0.0275 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0011 | 0.0054 | 0.0081 |
Trichomonas vaginalis | G protein (olf) alpha subunit, gnal, putative | 0.0022 | 0.0201 | 0.5 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0103 | 0.1305 | 0.194 |
Brugia malayi | nuclear receptor NHR-67 | 0.001 | 0.0039 | 0.0039 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0039 |
Onchocerca volvulus | 0.0021 | 0.0185 | 0.016 | |
Brugia malayi | vab-3 gene. | 0.0014 | 0.0101 | 0.0101 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0054 | 0.0054 |
Schistosoma mansoni | GTP-binding protein alpha subunit gna | 0.0022 | 0.0201 | 0.0299 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0095 | 0.1194 | 0.1774 |
Brugia malayi | Guanine nucleotide-binding protein alpha-3 subunit, putative | 0.0022 | 0.0201 | 0.0201 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0744 | 0.1106 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0361 | 0.4786 | 0.4786 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0021 | 0.0185 | 0.0275 |
Brugia malayi | nuclear hormone receptor | 0.0021 | 0.0185 | 0.0185 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.0185 | 0.0185 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.0054 | 0.0081 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0021 | 0.0185 | 0.0185 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0077 | 0.0949 | 0.1411 |
Brugia malayi | 'Paired box' domain containing protein | 0.0014 | 0.0101 | 0.0101 |
Brugia malayi | MH2 domain containing protein | 0.0011 | 0.0057 | 0.0057 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0103 | 0.1305 | 0.194 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0054 | 0.0054 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0.0185 | 0.0275 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0025 | 0.024 | 0.0357 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.2302 | 0.2302 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0744 | 0.1106 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0949 | 0.5 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0095 | 0.1194 | 0.1774 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0021 | 0.0185 | 0.0275 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0009 | 0.0026 | 0.0038 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0505 | 0.6727 | 1 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0177 | 0.2302 | 0.2282 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.0744 | 0.0744 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0505 | 0.6727 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.0744 | 0.0744 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0185 | 0.0185 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0301 | 0.3972 | 0.3972 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0249 | 1 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0077 | 0.0949 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0361 | 0.4786 | 0.4786 |
Echinococcus multilocularis | paired box protein pax 1 | 0.0014 | 0.0101 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | paired box protein | 0.0014 | 0.0101 | 0.0101 |
Echinococcus granulosus | FTZ F1 alpha | 0.0411 | 0.5459 | 0.8115 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0.0185 | 0.0275 |
Brugia malayi | nuclear receptor RXR | 0.001 | 0.0039 | 0.0039 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0505 | 0.6727 | 1 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.001 | 0.0039 | 0.0058 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.001 | 0.0039 | 0.0039 |
Schistosoma mansoni | hypothetical protein | 0.0095 | 0.1194 | 0.1774 |
Brugia malayi | MH2 domain containing protein | 0.0025 | 0.024 | 0.024 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.001 | 0.0039 | 0.0039 |
Schistosoma mansoni | hypothetical protein | 0.0095 | 0.1194 | 0.1774 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0021 | 0.0185 | 0.0185 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0009 | 0.0026 | 0.0038 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0744 | 0.1106 |
Schistosoma mansoni | regulator of G protein signaling | 0.0009 | 0.0026 | 0.0038 |
Entamoeba histolytica | G protein alpha subunit, putative | 0.0022 | 0.0201 | 0.5 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0025 | 0.024 | 0.0357 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.0129 | 0.0192 |
Brugia malayi | RasGEF domain containing protein | 0.0009 | 0.0024 | 0.0024 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0077 | 0.0949 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0021 | 0.0185 | 0.0185 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0201 | 0.0201 |
Trichomonas vaginalis | GTP-binding protein alpha subunit, gna, putative | 0.0022 | 0.0201 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0206 | 0.2686 | 0.2686 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0026 | 0.0026 |
Brugia malayi | hypothetical protein | 0.0157 | 0.2023 | 0.2023 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0021 | 0.0185 | 0.0275 |
Brugia malayi | ecdysone receptor | 0.001 | 0.0039 | 0.0039 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0011 | 0.0061 | 0.0091 |
Onchocerca volvulus | Retinal homeobox protein Rx homolog | 0.0014 | 0.0101 | 0.0076 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.001 | 0.0039 | 0.0058 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0103 | 0.1305 | 0.1305 |
Echinococcus granulosus | tyrosine protein kinase ABL1 | 0.0211 | 0.2754 | 0.4095 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0039 | 0.0039 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0021 | 0.0185 | 0.0275 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.001 | 0.0039 | 0.0058 |
Schistosoma mansoni | dishevelled | 0.0009 | 0.0026 | 0.0038 |
Loa Loa (eye worm) | DR-78 | 0.001 | 0.0039 | 0.0039 |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.0129 | 0.0129 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.0744 | 0.1106 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.001 | 0.0039 | 0.0058 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0009 | 0.0026 | 0.0038 |
Brugia malayi | Smad1 | 0.0025 | 0.024 | 0.024 |
Schistosoma mansoni | trimeric G-protein alpha o subunit | 0.0022 | 0.0201 | 0.0299 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0009 | 0.0026 | 0.0038 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0011 | 0.0054 | 0.0081 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0128 | 0.0128 |
Loa Loa (eye worm) | guanine nucleotide-binding protein alpha-12 subunit | 0.0022 | 0.0201 | 0.0201 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0505 | 0.6727 | 1 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.0129 | 0.1119 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0051 | 0.059 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.0744 | 0.0744 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0505 | 0.6727 | 0.6727 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0039 | 0.0058 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0129 | 0.0192 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0505 | 0.6727 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.001 | 0.0039 | 0.0039 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0021 | 0.0185 | 0.0275 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0.0185 | 0.0275 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0025 | 0.024 | 0.0357 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0021 | 0.0185 | 0.0275 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0077 | 0.0949 | 0.1411 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0009 | 0.0026 | 0.0026 |
Trichomonas vaginalis | GTP-binding protein alpha subunit, gna, putative | 0.0022 | 0.0201 | 0.5 |
Brugia malayi | tailless protein | 0.001 | 0.0039 | 0.0039 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0009 | 0.0026 | 0.0026 |
Echinococcus multilocularis | guanine nucleotide binding protein subunit | 0.0022 | 0.0201 | 0.0299 |
Loa Loa (eye worm) | TK/ABL protein kinase | 0.0211 | 0.2754 | 0.2754 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | > 83.3 uM | Inhibition of human recombinant His6-tagged PI3K p110alpha expressed in baculovirus using DiC8-PI(4,5)P2 as substrate after 20 mins by AlphaScreen assay | ChEMBL. | 23010274 |
IC50 (binding) | = 110 uM | Inhibition of human recombinant His6-tagged PI3K p110beta expressed in baculovirus using DiC8-PI(4,5)P2 as substrate after 20 mins by AlphaScreen assay | ChEMBL. | 23010274 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.