Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0214 | 1 | 1 | |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.0305 | 0.1499 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0054 | 0.2037 | 1 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0214 | 1 | 1 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0214 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0214 | 1 | 1 |
Echinococcus granulosus | orexin receptor type 2 | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Schistosoma mansoni | amine GPCR | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0214 | 1 | 1 |
Brugia malayi | Dopamine receptor protein 2 | 0.0214 | 1 | 1 |
Schistosoma mansoni | rab6-interacting | 0.0021 | 0.0406 | 0.0104 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0042 | 0.144 | 1 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0214 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0305 | 0.1499 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0021 | 0.0406 | 0.0104 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0214 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0214 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.2969 | 1 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0214 | 1 | 1 |
Onchocerca volvulus | 0.0214 | 1 | 1 | |
Trypanosoma brucei | unspecified product | 0.0019 | 0.0305 | 0.1499 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0214 | 1 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.0305 | 0.1499 |
Schistosoma mansoni | loxhd1 | 0.0021 | 0.0406 | 0.0104 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0305 | 0.1499 |
Echinococcus multilocularis | serotonin receptor | 0.0214 | 1 | 1 |
Echinococcus granulosus | RUN | 0.0021 | 0.0406 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0214 | 1 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0214 | 1 | 1 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0021 | 0.0406 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0406 | 0.0406 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0214 | 1 | 1 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0054 | 0.2037 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0406 | 0.0104 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0305 | 0.1499 |
Brugia malayi | AKH receptor | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0214 | 1 | 1 |
Schistosoma mansoni | amine GPCR | 0.0214 | 1 | 1 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0038 | 0.1268 | 0.3615 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0058 | 0.2259 | 0.2015 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0054 | 0.2037 | 0.1786 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0214 | 1 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0214 | 1 | 1 |
Schistosoma mansoni | lipoxygenase | 0.0058 | 0.2259 | 0.2015 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.0305 | 0.1499 |
Schistosoma mansoni | neuropeptide receptor | 0.0214 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0305 | 0.1499 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0214 | 1 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0054 | 0.2037 | 0.1786 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0214 | 1 | 1 |
Schistosoma mansoni | amine GPCR | 0.0214 | 1 | 1 |
Onchocerca volvulus | 0.0214 | 1 | 1 | |
Brugia malayi | neuropeptide F receptor | 0.0214 | 1 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0214 | 1 | 1 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0054 | 0.2037 | 0.1786 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0214 | 1 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.0214 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0214 | 1 | 1 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0141 | 0.6395 | 0.6281 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0305 | 0.1499 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0072 | 0.2969 | 0.2748 |
Schistosoma mansoni | adenoreceptor | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0305 | 0.0305 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0141 | 0.6395 | 0.6281 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0214 | 1 | 1 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0214 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.2969 | 1 |
Echinococcus multilocularis | serotonin receptor | 0.0214 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0214 | 1 | 1 |
Onchocerca volvulus | 0.0214 | 1 | 1 | |
Schistosoma mansoni | serine/threonine protein kinase | 0.0054 | 0.2037 | 0.1786 |
Onchocerca volvulus | 0.0214 | 1 | 1 | |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0054 | 0.2037 | 1 |
Onchocerca volvulus | 0.0214 | 1 | 1 | |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0214 | 1 | 1 |
Echinococcus multilocularis | allatostatin A receptor | 0.0214 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0305 | 0.1499 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.0305 | 0.1499 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0214 | 1 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.0305 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0054 | 0.2037 | 1 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0214 | 1 | 1 |
Trypanosoma brucei | protein kinase, putative | 0.0054 | 0.2037 | 1 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0214 | 1 | 1 |
Brugia malayi | follicle stimulating hormone receptor | 0.0214 | 1 | 1 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Echinococcus multilocularis | sex peptide receptor | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0214 | 1 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0214 | 1 | 1 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0214 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0214 | 1 | 1 |
Onchocerca volvulus | 0.0214 | 1 | 1 | |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0406 | 0.0406 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0214 | 1 | 1 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0042 | 0.144 | 0.6554 |
Brugia malayi | Serotonin receptor | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0054 | 0.2037 | 0.2037 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0214 | 1 | 1 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0021 | 0.0406 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0214 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0214 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0214 | 1 | 1 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0214 | 1 | 1 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0214 | 1 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0214 | 1 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.0214 | 1 | 1 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0406 | 0.0406 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0054 | 0.2037 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0305 | 0.0305 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0038 | 0.1268 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.0017 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0214 | 1 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.0305 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Onchocerca volvulus | 0.0214 | 1 | 1 | |
Brugia malayi | putative neuropeptide receptor | 0.0214 | 1 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0214 | 1 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0305 | 0.0305 |
Schistosoma mansoni | biogenic amine receptor | 0.0214 | 1 | 1 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0305 | 0.1499 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0214 | 1 | 1 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0214 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0181 | 0.8379 | 0.8328 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0214 | 1 | 1 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0214 | 1 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0054 | 0.2037 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0181 | 0.8379 | 0.8379 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Echinococcus granulosus | somatostatin receptor | 0.0214 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0181 | 0.8379 | 0.8328 |
Onchocerca volvulus | 0.0214 | 1 | 1 | |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0305 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.0017 | 0.0083 |
Schistosoma mansoni | hypothetical protein | 0.0214 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0305 | 0.1499 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0021 | 0.0406 | 0.0104 |
Brugia malayi | hypothetical protein | 0.0072 | 0.2969 | 0.2969 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0214 | 1 | 1 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0214 | 1 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0214 | 1 | 1 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0214 | 1 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0214 | 1 | 1 |
Onchocerca volvulus | 0.0214 | 1 | 1 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0181 | 0.8379 | 0.8328 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0214 | 1 | 1 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0214 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0214 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.2969 | 1 |
Schistosoma mansoni | rab6-interacting | 0.0021 | 0.0406 | 0.0104 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0021 | 0.0406 | 0.0104 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0214 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0305 | 0.1499 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Onchocerca volvulus | 0.0214 | 1 | 1 | |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0214 | 1 | 1 |
Echinococcus granulosus | sex peptide receptor | 0.0214 | 1 | 1 |
Brugia malayi | Dopamine receptor protein 1 | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | doublecortin family protein | 0.0021 | 0.0406 | 0.0406 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0054 | 0.2037 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0181 | 0.8379 | 0.8328 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0305 | 0.1499 |
Brugia malayi | G-protein coupled receptor | 0.0214 | 1 | 1 |
Onchocerca volvulus | 0.0214 | 1 | 1 | |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0214 | 1 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0054 | 0.2037 | 1 |
Brugia malayi | Melatonin receptor type 1A | 0.0214 | 1 | 1 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0214 | 1 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.0305 | 0.1499 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0214 | 1 | 1 |
Echinococcus granulosus | allatostatin A receptor | 0.0214 | 1 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0214 | 1 | 1 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0214 | 1 | 1 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0214 | 1 | 1 |
Brugia malayi | Serotonin receptor | 0.0214 | 1 | 1 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0054 | 0.2037 | 1 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0214 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0214 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0305 | 0.1499 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0214 | 1 | 1 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0214 | 1 | 1 |
Echinococcus granulosus | neuropeptide s receptor | 0.0214 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0181 | 0.8379 | 0.8328 |
Echinococcus granulosus | serotonin receptor | 0.0214 | 1 | 1 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0038 | 0.1268 | 0.5561 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0214 | 1 | 1 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0042 | 0.144 | 0.1171 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0305 | 0.1499 |
Schistosoma mansoni | amine GPCR | 0.0214 | 1 | 1 |
Brugia malayi | larval opioid receptor | 0.0214 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0214 | 1 | 1 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0214 | 1 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0214 | 1 | 1 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0054 | 0.2037 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0305 | 0.1499 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0214 | 1 | 1 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0214 | 1 | 1 |
Onchocerca volvulus | 0.0214 | 1 | 1 | |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0214 | 1 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0054 | 0.2037 | 0.1786 |
Brugia malayi | Doublecortin family protein | 0.0021 | 0.0406 | 0.0406 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0054 | 0.2037 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Onchocerca volvulus | 0.0214 | 1 | 1 | |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0214 | 1 | 1 |
Echinococcus granulosus | fmrfamide receptor | 0.0214 | 1 | 1 |
Brugia malayi | MAP kinase sur-1 | 0.0054 | 0.2037 | 0.2037 |
Echinococcus multilocularis | neuropeptide receptor | 0.0214 | 1 | 1 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0042 | 0.144 | 0.6554 |
Brugia malayi | hypothetical protein | 0.0214 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0214 | 1 | 1 |
Brugia malayi | GnHR receptor homolog | 0.0214 | 1 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0214 | 1 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0214 | 1 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0214 | 1 | 1 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0214 | 1 | 1 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0214 | 1 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0214 | 1 | 1 |
Onchocerca volvulus | 0.0214 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0214 | 1 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0214 | 1 | 1 |
Echinococcus granulosus | g-protein coupled receptor | 0.0214 | 1 | 1 |
Schistosoma mansoni | polycystin 1-related | 0.0021 | 0.0406 | 0.0104 |
Brugia malayi | sulfakinin receptor protein | 0.0214 | 1 | 1 |
Onchocerca volvulus | 0.0214 | 1 | 1 | |
Brugia malayi | Dopamine receptor | 0.0214 | 1 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0072 | 0.2969 | 0.2748 |
Brugia malayi | hypothetical protein | 0.0214 | 1 | 1 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0214 | 1 | 1 |
Schistosoma mansoni | lipoxygenase | 0.0021 | 0.0406 | 0.0104 |
Echinococcus granulosus | g protein coupled receptor | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0181 | 0.8379 | 0.8379 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0058 | 0.2259 | 0.2015 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.2969 | 1 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0214 | 1 | 1 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0214 | 1 | 1 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0214 | 1 | 1 |
Brugia malayi | G-protein coupled receptor | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0214 | 1 | 1 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0214 | 1 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.0214 | 1 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0214 | 1 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0214 | 1 | 1 |
Brugia malayi | G protein-coupled receptor | 0.0214 | 1 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Brugia malayi | neuropeptide F receptor | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.0305 | 0.0305 |
Schistosoma mansoni | opsin-like receptor | 0.0214 | 1 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.0214 | 1 | 1 |
Brugia malayi | ORL1-like opioid receptor | 0.0214 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0214 | 1 | 1 |
Echinococcus multilocularis | neuropeptide receptor | 0.0214 | 1 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0214 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0214 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0214 | 1 | 1 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0214 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0181 | 0.8379 | 0.8328 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0214 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0305 | 0.1499 |
Schistosoma mansoni | hypothetical protein | 0.0072 | 0.2969 | 0.2748 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0214 | 1 | 1 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0141 | 0.6395 | 0.6395 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0305 | 0.1499 |
Echinococcus granulosus | g protein coupled receptor | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0214 | 1 | 1 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0214 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0305 | 0.1499 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0305 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0214 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0406 | 0.0406 |
Schistosoma mansoni | amine GPCR | 0.0214 | 1 | 1 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | acetyltransferase | 0.0141 | 0.6395 | 0.6395 |
Brugia malayi | RE15519p | 0.0214 | 1 | 1 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0214 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0054 | 0.2037 | 1 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0214 | 1 | 1 |
Onchocerca volvulus | 0.0214 | 1 | 1 | |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0214 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0181 | 0.8379 | 0.8328 |
Echinococcus multilocularis | somatostatin receptor | 0.0214 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 1 | 1 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0137 | 0.6198 | 0.6078 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0305 | 0.1499 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0214 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0013 | 0.0017 | 0.0083 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0214 | 1 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.0214 | 1 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0072 | 0.2969 | 0.2748 |
Schistosoma mansoni | opsin-like receptor | 0.0214 | 1 | 1 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0214 | 1 | 1 |
Schistosoma mansoni | histamine h1 receptor | 0.0214 | 1 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0054 | 0.2037 | 1 |
Schistosoma mansoni | myosin xvIII | 0.0214 | 1 | 1 |
Echinococcus multilocularis | RUN | 0.0021 | 0.0406 | 0.0104 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0214 | 1 | 1 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0021 | 0.0406 | 0.0104 |
Trypanosoma brucei | unspecified product | 0.0013 | 0.0017 | 0.0083 |
Brugia malayi | hypothetical protein | 0.0214 | 1 | 1 |
Trypanosoma brucei | unspecified product | 0.0013 | 0.0017 | 0.0083 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0214 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 58 % | Analgesic activity in mouse assessed as inhibition of acetic acid-induced writhing response at 10 mg/kg, po administered 0.5 to 1 hr before acetic acid challenge | ChEMBL. | 22386241 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.