TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 497.255 | Formula: C22H24BrCl2N3O--
H donors: 1 H acceptors: 1 LogP: 4.94 Rotable bonds: 4
Rule of 5 violations (Lipinski): 1
SMILES: OCCN1CCN(CC1)C1=Nc2ccccc2CC=C1c1ccc(cc1)Br.[Cl-].[Cl-]
InChi: 1S/C22H24BrN3O.2ClH/c23-19-8-5-17(6-9-19)20-10-7-18-3-1-2-4-21(18)24-22(20)26-13-11-25(12-14-26)15-16-27;;/h1-6,8-10,27H,7,11-16H2;2*1H/p-2
InChiKey: WQBPUVDOCSYPMT-UHFFFAOYSA-L

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	alpha-glucosidase	0.0148	0.04	0.0369
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0086	0.0076
Loa Loa (eye worm)	calcium channel	0.012	0.031	0.03
Brugia malayi	Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog	0.012	0.031	0.03
Trypanosoma cruzi	major cysteine proteinase, putative	0.0057	0.0104	0.0094
Trypanosoma cruzi	3-hydroxy-3-methylglutaryl-CoA reductase, putative	0.3066	1	1
Loa Loa (eye worm)	exodeoxyribonuclease III family protein	0.004	0.0046	0.0036
Echinococcus multilocularis	protein patched	0.1262	0.4067	0.4043
Trypanosoma brucei	glucosidase, putative	0.0038	0.004	0.003
Schistosoma mansoni	transient receptor potential cation channel subfamily m member	0.012	0.031	0.0278
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0052	0.0088	0.0078
Echinococcus granulosus	transient receptor potential cation channel	0.012	0.031	0.0271
Trypanosoma cruzi	peptidyl-prolyl cis-trans isomerase	0.0039	0.0043	0.0033
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0092	0.0219	0.018
Schistosoma mansoni	hypothetical protein	0.0164	0.0454	0.0423
Echinococcus multilocularis	potassium large conductance calcium activated	0.012	0.031	0.0271
Trypanosoma brucei	DNA polymerase kappa, putative	0.0046	0.0067	0.0057
Loa Loa (eye worm)	hypothetical protein	0.012	0.031	0.03
Echinococcus multilocularis	two pore calcium channel protein 1	0.012	0.031	0.0271
Schistosoma mansoni	voltage-gated potassium channel	0.012	0.031	0.0278
Leishmania major	3-hydroxy-3-methylglutaryl-CoA reductase	0.3066	1	1
Echinococcus granulosus	potassium voltage gated channel subfamily D	0.012	0.031	0.0271
Toxoplasma gondii	ImpB/MucB/SamB family protein	0.0045	0.0062	0.174
Loa Loa (eye worm)	hypothetical protein	0.012	0.031	0.03
Echinococcus multilocularis	hyperpolarization activated cyclic	0.012	0.031	0.0271
Echinococcus granulosus	Protein patched homolog 1	0.1262	0.4067	0.4043
Brugia malayi	Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog	0.012	0.031	0.03
Schistosoma mansoni	transcription factor LCR-F1	0.0038	0.004	0.0007
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0046	0.0067	0.0057
Loa Loa (eye worm)	ryanodine receptor	0.012	0.031	0.03
Loa Loa (eye worm)	voltage and ligand gated potassium channel	0.012	0.031	0.03
Trypanosoma cruzi	3-hydroxy-3-methylglutaryl-CoA reductase	0.3066	1	1
Loa Loa (eye worm)	hypothetical protein	0.012	0.031	0.03
Echinococcus multilocularis	transient receptor potential cation channel	0.012	0.031	0.0271
Echinococcus multilocularis	potassium voltage gated channel protein	0.012	0.031	0.0271
Echinococcus granulosus	shaker cognate	0.012	0.031	0.0271
Trypanosoma brucei	Voltage-dependent calcium channel subunit, putative	0.012	0.031	0.03
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.012	0.031	0.0271
Trypanosoma brucei	inositol 1,4,5-trisphosphate receptor	0.012	0.031	0.03
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.012	0.031	0.0271
Echinococcus multilocularis	potassium voltage gated channel subfamily D	0.012	0.031	0.0271
Trichomonas vaginalis	DNA polymerase eta, putative	0.0046	0.0067	0.0058
Echinococcus granulosus	voltage dependent L type calcium channel subunit\|voltage dependent calcium channel	0.012	0.031	0.0271
Loa Loa (eye worm)	hypothetical protein	0.1262	0.4067	0.4061
Echinococcus multilocularis	transient receptor potential cation channel	0.012	0.031	0.0271
Giardia lamblia	3-hydroxy-3-methylglutaryl-coenzyme A reductase	0.1439	0.4646	1
Trypanosoma brucei	DNA polymerase IV, putative	0.0046	0.0067	0.0057
Trypanosoma cruzi	hypothetical protein, conserved	0.0038	0.004	0.003
Echinococcus granulosus	voltage dependent calcium channel type d subunit\|voltage dependent calcium channel alpha 1	0.012	0.031	0.0271
Echinococcus multilocularis	hyperpolarization activated cyclic	0.012	0.031	0.0271
Loa Loa (eye worm)	hypothetical protein	0.012	0.031	0.03
Echinococcus granulosus	transient receptor potential cation channel	0.012	0.031	0.0271
Mycobacterium tuberculosis	Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI)	0.004	0.0046	0.0849
Toxoplasma gondii	transporter, cation channel family protein	0.012	0.031	1
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.012	0.031	0.0271
Echinococcus multilocularis	two pore calcium channel protein 2	0.012	0.031	0.0271
Echinococcus multilocularis	Niemann Pick C1 protein	0.1262	0.4067	0.4043
Trypanosoma cruzi	mitochondrial DNA polymerase beta-PAK, putative	0.0051	0.0082	0.0072
Trypanosoma brucei	unspecified product	0.0046	0.0067	0.0057
Trichomonas vaginalis	3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative	0.1439	0.4646	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0073	0.0156	0.0146
Leishmania major	peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative	0.0039	0.0043	0.0033
Entamoeba histolytica	glycosyl hydrolase, family 31 protein	0.0038	0.004	0.0003
Echinococcus multilocularis	voltage dependent calcium channel type d subunit	0.012	0.031	0.0271
Brugia malayi	Cyclic-nucleotide gated cation channel	0.012	0.031	0.03
Loa Loa (eye worm)	cyclic-nucleotide gated cation channel	0.012	0.031	0.03
Echinococcus multilocularis	expressed protein	0.004	0.0046	0.0007
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0073	0.0156	0.0146
Trypanosoma cruzi	DNA polymerase eta, putative	0.0045	0.0062	0.0052
Echinococcus granulosus	expressed protein	0.004	0.0046	0.0007
Toxoplasma gondii	transporter, cation channel family protein	0.012	0.031	1
Echinococcus granulosus	potassium voltage gated channel subfamily D	0.012	0.031	0.0271
Schistosoma mansoni	hypothetical protein	0.0164	0.0454	0.0423
Echinococcus granulosus	potassium voltage gated channel protein	0.012	0.031	0.0271
Schistosoma mansoni	aldehyde dehydrogenase	0.0118	0.0302	0.027
Echinococcus multilocularis	dna polymerase eta	0.0077	0.0167	0.0128
Schistosoma mansoni	ap endonuclease	0.004	0.0046	0.0013
Mycobacterium ulcerans	DNA polymerase IV	0.0046	0.0067	0.0067
Echinococcus granulosus	sodium channel protein	0.012	0.031	0.0271
Schistosoma mansoni	alpha glucosidase	0.0038	0.004	0.0007
Echinococcus granulosus	voltage gated hydrogen channel 1	0.012	0.031	0.0271
Leishmania major	DNA polymerase eta, putative	0.0045	0.0062	0.0052
Echinococcus multilocularis	dna polymerase kappa	0.0046	0.0067	0.0027
Loa Loa (eye worm)	hypothetical protein	0.012	0.031	0.03
Leishmania major	DNA polymerase eta, putative	0.0077	0.0167	0.0157
Echinococcus granulosus	potassium voltage gated channel protein	0.012	0.031	0.0271
Trypanosoma cruzi	Voltage-dependent calcium channel subunit, putative	0.012	0.031	0.03
Brugia malayi	Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog	0.012	0.031	0.03
Wolbachia endosymbiont of Brugia malayi	exonuclease III	0.004	0.0046	1
Schistosoma mansoni	rab geranylgeranyl transferase alpha subunit	0.0046	0.0067	0.0034
Toxoplasma gondii	aldehyde dehydrogenase	0.0118	0.0302	0.9733
Echinococcus multilocularis	potassium voltage gated channel protein	0.012	0.031	0.0271
Brugia malayi	Glycosyl hydrolases family 31 protein	0.0038	0.004	0.003
Schistosoma mansoni	voltage-gated potassium channel	0.012	0.031	0.0278
Trichomonas vaginalis	conserved hypothetical protein	0.004	0.0046	0.0013
Echinococcus granulosus	potassium large conductance calcium activated	0.012	0.031	0.0271
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.012	0.031	0.0278
Leishmania major	mitochondrial DNA polymerase beta	0.0361	0.1102	0.1093
Echinococcus multilocularis	voltage gated potassium channel	0.012	0.031	0.0271
Echinococcus granulosus	transient receptor potential gamma protein	0.012	0.031	0.0271
Echinococcus multilocularis	transient receptor potential gamma protein	0.012	0.031	0.0271
Echinococcus multilocularis	shaker cognate	0.012	0.031	0.0271
Echinococcus granulosus	hydroxymethylglutaryl coenzyme A reductase	0.3066	1	1
Onchocerca volvulus		0.0173	0.0485	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0032	0.002	0.001
Brugia malayi	Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit	0.012	0.031	0.03
Leishmania major	cathepsin L-like protease	0.0073	0.0156	0.0146
Leishmania major	cathepsin L-like protease	0.0073	0.0156	0.0146
Loa Loa (eye worm)	hypothetical protein	0.012	0.031	0.03
Brugia malayi	ImpB/MucB/SamB family protein	0.0077	0.0167	0.0157
Schistosoma mansoni	transient receptor potential channel	0.012	0.031	0.0278
Toxoplasma gondii	hypothetical protein	0.012	0.031	1
Echinococcus granulosus	potassium voltage gated channel subfamily D	0.012	0.031	0.0271
Trypanosoma brucei	DNA polymerase kappa, putative	0.0046	0.0067	0.0057
Echinococcus granulosus	voltage gated potassium channel	0.012	0.031	0.0271
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0073	0.0156	0.0146
Echinococcus granulosus	voltage gated sodium channel Nav1 alpha subunit	0.012	0.031	0.0271
Schistosoma mansoni	two-pore calcium channel	0.012	0.031	0.0278
Echinococcus multilocularis	voltage dependent calcium channel type d subunit	0.012	0.031	0.0271
Leishmania major	hypothetical protein, unknown function	0.012	0.031	0.03
Trypanosoma cruzi	peptidyl-prolyl cis-trans isomerase	0.0039	0.0043	0.0033
Echinococcus multilocularis	potassium voltage gated channel protein	0.012	0.031	0.0271
Mycobacterium ulcerans	hypothetical protein	0.019	0.054	0.054
Schistosoma mansoni	voltage-gated ion channel	0.012	0.031	0.0278
Echinococcus granulosus	cyclic nucleotide gated cation channel	0.012	0.031	0.0271
Echinococcus multilocularis	voltage dependent L type calcium channel subunit	0.012	0.031	0.0271
Echinococcus multilocularis	sodium leak channel non selective protein	0.012	0.031	0.0271
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0052	0.0088	0.0078
Echinococcus multilocularis	DNA (apurinic or apyrimidinic site) lyase	0.004	0.0046	0.0006
Schistosoma mansoni	voltage-gated potassium channel	0.012	0.031	0.0278
Trichomonas vaginalis	conserved hypothetical protein	0.0197	0.0563	0.1135
Loa Loa (eye worm)	hypothetical protein	0.012	0.031	0.03
Trypanosoma cruzi	mitochondrial DNA polymerase beta-PAK, putative	0.0171	0.0477	0.0467
Echinococcus multilocularis	atpase aaa+ type core atpase aaa type core	0.0853	0.2721	0.2692
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.012	0.031	0.0586
Brugia malayi	hypothetical protein	0.012	0.031	0.03
Schistosoma mansoni	transient receptor potential channel	0.012	0.031	0.0278
Echinococcus granulosus	Niemann Pick C1 protein	0.1262	0.4067	0.4043
Schistosoma mansoni	voltage-gated potassium channel	0.012	0.031	0.0278
Schistosoma mansoni	transient receptor potential cation channel subfamily m member	0.012	0.031	0.0278
Loa Loa (eye worm)	hypothetical protein	0.012	0.031	0.03
Schistosoma mansoni	60S ribosomal protein L21	0.012	0.031	0.0278
Schistosoma mansoni	niemann-pick C1 (NPC1)	0.1262	0.4067	0.4047
Schistosoma mansoni	transient receptor potential channel 4	0.012	0.031	0.0278
Echinococcus granulosus	potassium voltage gated channel subfamily C	0.012	0.031	0.0271
Loa Loa (eye worm)	hypothetical protein	0.012	0.031	0.03
Giardia lamblia	DINP protein human, muc B family	0.0046	0.0067	0.0046
Brugia malayi	Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog	0.012	0.031	0.03
Echinococcus granulosus	sodium leak channel non selective protein	0.012	0.031	0.0271
Toxoplasma gondii	exonuclease III APE	0.004	0.0046	0.1191
Echinococcus multilocularis	sodium channel protein	0.012	0.031	0.0271
Echinococcus granulosus	DNA apurinic or apyrimidinic site lyase	0.004	0.0046	0.0006
Echinococcus granulosus	ryanodine receptor 44f	0.012	0.031	0.0271
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.0067	0.0135	0.0125
Schistosoma mansoni	voltage-gated potassium channel	0.012	0.031	0.0278
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0046	0.0067	0.0057
Trypanosoma cruzi	cruzipain precursor, putative	0.0073	0.0156	0.0146
Echinococcus granulosus	short transient receptor potential channel 6	0.012	0.031	0.0271
Echinococcus multilocularis	voltage gated potassium channel	0.012	0.031	0.0271
Echinococcus granulosus	hyperpolarization activated cyclic	0.012	0.031	0.0271
Trichomonas vaginalis	3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative	0.1439	0.4646	1
Echinococcus granulosus	survival motor neuron protein 1	0.0249	0.0733	0.0696
Echinococcus granulosus	potassium:sodium hyperpolarization activated	0.012	0.031	0.0271
Brugia malayi	Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog	0.012	0.031	0.03
Loa Loa (eye worm)	hypothetical protein	0.012	0.031	0.03
Echinococcus multilocularis	transfer RNA-Gly	0.012	0.031	0.0271
Brugia malayi	Glycosyl hydrolases family 31 protein	0.0171	0.0479	0.0469
Trypanosoma brucei	DNA polymerase kappa, putative	0.0046	0.0067	0.0057
Echinococcus multilocularis	short transient receptor potential channel 6	0.012	0.031	0.0271
Toxoplasma gondii	hypothetical protein	0.012	0.031	1
Echinococcus granulosus	cyclic nucleotide gated cation channel	0.012	0.031	0.0271
Echinococcus multilocularis	potassium voltage gated channel subfamily KQT	0.012	0.031	0.0271
Chlamydia trachomatis	transglycolase/transpeptidase	0.0026	0	0.5
Trypanosoma brucei	3-hydroxy-3-methylglutaryl-CoA reductase, putative	0.3066	1	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0046	0.0067	0.0057
Echinococcus granulosus	potassium voltage gated channel protein	0.012	0.031	0.0271
Schistosoma mansoni	voltage-gated potassium channel KCNQ	0.012	0.031	0.0278
Trypanosoma cruzi	hypothetical protein, conserved	0.0038	0.004	0.003
Loa Loa (eye worm)	voltage-gated potassium channel	0.012	0.031	0.03
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0092	0.0219	0.0209
Echinococcus multilocularis	survival motor neuron protein 1	0.0249	0.0733	0.0696
Echinococcus granulosus	dna polymerase eta	0.0077	0.0167	0.0128
Loa Loa (eye worm)	Pin1-type peptidyl-prolyl cis-trans isomerase	0.004	0.0046	0.0036
Trypanosoma brucei	unspecified product	0.0032	0.002	0.001
Schistosoma mansoni	voltage-gated potassium channel	0.012	0.031	0.0278
Leishmania major	hypothetical protein, conserved	0.012	0.031	0.03
Plasmodium vivax	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.004	0.0046	1
Echinococcus granulosus	hyperpolarization activated cyclic	0.012	0.031	0.0271
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0046	0.0067	0.0057
Trypanosoma brucei	DNA polymerase kappa, putative	0.0046	0.0067	0.0057
Mycobacterium ulcerans	bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2	0.0109	0.0274	0.0274
Onchocerca volvulus		0.0052	0.0086	0.0105
Loa Loa (eye worm)	ion channel NompC	0.012	0.031	0.03
Schistosoma mansoni	calcium channel voltage-dependent p/q type alpha 1a-related	0.012	0.031	0.0278
Brugia malayi	exodeoxyribonuclease III family protein	0.004	0.0046	0.0036
Brugia malayi	olfactory channel protein osm-9	0.012	0.031	0.03
Schistosoma mansoni	terminal deoxycytidyl transferase	0.0046	0.0067	0.0034
Trichomonas vaginalis	ap endonuclease, putative	0.004	0.0046	0.0012
Brugia malayi	Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1	0.004	0.0046	0.0036
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.012	0.031	0.0586
Loa Loa (eye worm)	cyclic-nucleotide gated cation channel	0.012	0.031	0.03
Loa Loa (eye worm)	hypothetical protein	0.012	0.031	0.03
Mycobacterium leprae	PROBABLE BIFUNCTIONAL PENICILLIN-BINDING PROTEIN 1A/1B PONA1 (MUREIN POLYMERASE) (PBP1): PENICILLIN-INSENSITIVE TRANSGLYCOSYLASE	0.0197	0.0563	1
Schistosoma mansoni	voltage-gated potassium channel	0.012	0.031	0.0278
Loa Loa (eye worm)	hypothetical protein	0.0173	0.0485	0.0475
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0073	0.0156	0.0146
Trypanosoma cruzi	cysteine peptidase, putative	0.0073	0.0156	0.0146
Leishmania major	mitochondrial DNA polymerase beta-PAK, putative	0.0171	0.0477	0.0467
Echinococcus granulosus	sterol regulatory element binding protein	0.1262	0.4067	0.4043
Schistosoma mansoni	voltage-gated potassium channel	0.012	0.031	0.0278
Echinococcus granulosus	calcium activated potassium channel	0.012	0.031	0.0271
Echinococcus multilocularis	potassium voltage gated channel subfamily D	0.012	0.031	0.0271
Onchocerca volvulus	Transient receptor potential cation channel trpm homolog	0.012	0.031	0.5656
Leishmania major	DNA polymerase kappa, putative,DNA polymerase IV, putative	0.0046	0.0067	0.0057
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0118	0.0302	0.0302
Mycobacterium tuberculosis	Probable aldehyde dehydrogenase	0.0118	0.0302	0.5586
Brugia malayi	hypothetical protein	0.0249	0.0733	0.0724
Trypanosoma cruzi	DNA polymerase beta thumb, putative	0.0051	0.0082	0.0072
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease, putative	0.004	0.0046	0.0036
Brugia malayi	CHE-14 protein	0.1262	0.4067	0.4061
Entamoeba histolytica	glycosyl hydrolase, family 31 protein	0.0038	0.004	0.0003
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0073	0.0156	0.0146
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0092	0.0219	0.018
Schistosoma mansoni	hyperpolarization activated cyclic nucleotide-gated potassium channel	0.012	0.031	0.0278
Echinococcus granulosus	transient receptor potential cation channel	0.012	0.031	0.0271
Trypanosoma brucei	DNA polymerase kappa, putative	0.0032	0.002	0.001
Echinococcus multilocularis	voltage dependent calcium channel	0.012	0.031	0.0271
Echinococcus multilocularis	cyclic nucleotide gated cation channel alpha 3	0.012	0.031	0.0271
Loa Loa (eye worm)	hypothetical protein	0.012	0.031	0.03
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0073	0.0156	0.0146
Mycobacterium ulcerans	hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase	0.3066	1	1
Brugia malayi	cation channel family protein	0.012	0.031	0.03
Toxoplasma gondii	transporter, cation channel family protein	0.012	0.031	1
Echinococcus granulosus	potassium voltage gated channel protein	0.012	0.031	0.0271
Brugia malayi	Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog	0.012	0.031	0.03
Trypanosoma brucei	unspecified product	0.0032	0.002	0.001
Mycobacterium tuberculosis	Probable bifunctional penicillin-binding protein 1A/1B PonA1 (murein polymerase) (PBP1): penicillin-insensitive transglycosylase	0.0088	0.0205	0.3788
Trypanosoma cruzi	DNA polymerase eta, putative	0.0077	0.0167	0.0157
Loa Loa (eye worm)	glycosyl hydrolase family 31 protein	0.0171	0.0479	0.0469
Brugia malayi	hypothetical protein	0.0038	0.004	0.0029
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0052	0.0088	0.0078
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0092	0.0219	0.0187
Echinococcus granulosus	transient receptor potential cation channel	0.012	0.031	0.0271
Trypanosoma cruzi	mitochondrial DNA polymerase beta-PAK, putative	0.0062	0.0119	0.0108
Schistosoma mansoni	hypothetical protein	0.0038	0.004	0.0007
Brugia malayi	Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog	0.012	0.031	0.03
Brugia malayi	Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit	0.012	0.031	0.03
Echinococcus granulosus	voltage dependent calcium channel	0.012	0.031	0.0271
Schistosoma mansoni	transient receptor potential cation channel subfamily m member	0.012	0.031	0.0278
Toxoplasma gondii	glycosyl hydrolase, family 31 protein	0.0038	0.004	0.1002
Schistosoma mansoni	hypothetical protein	0.012	0.031	0.0278
Echinococcus multilocularis	voltage dependent calcium channel	0.012	0.031	0.0271
Plasmodium falciparum	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.004	0.0046	1
Schistosoma mansoni	alpha-glucosidase	0.0148	0.04	0.0369
Trypanosoma brucei	peptidyl-prolyl cis-trans isomerase/rotamase, putative	0.0039	0.0043	0.0033
Loa Loa (eye worm)	voltage-gated calcium channel	0.012	0.031	0.03
Loa Loa (eye worm)	hypothetical protein	0.012	0.031	0.03
Echinococcus multilocularis	voltage gated hydrogen channel 1	0.012	0.031	0.0271
Loa Loa (eye worm)	glycosyl hydrolase family 31 protein	0.0038	0.004	0.003
Schistosoma mansoni	voltage-gated potassium channel	0.012	0.031	0.0278
Leishmania major	cathepsin L-like protease	0.0073	0.0156	0.0146
Echinococcus multilocularis	sterol regulatory element binding protein	0.1262	0.4067	0.4043
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0073	0.0156	0.0146
Trichomonas vaginalis	rotamase, putative	0.0039	0.0043	0.0007
Echinococcus multilocularis	lysosomal alpha glucosidase	0.0171	0.0479	0.0441
Echinococcus multilocularis	transient receptor potential cation channel	0.012	0.031	0.0271
Echinococcus multilocularis	calcium activated potassium channel	0.012	0.031	0.0271
Trypanosoma cruzi	DNA polymerase beta thumb, putative	0.0051	0.0082	0.0072
Schistosoma mansoni	voltage-gated potassium channel	0.012	0.031	0.0278
Trypanosoma brucei	apurinic/apyrimidinic endonuclease, putative	0.004	0.0046	0.0036
Mycobacterium tuberculosis	Probable bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 (murein polymerase) [includes: penicillin-insen	0.0109	0.0274	0.5062
Trichomonas vaginalis	pps1 dual specificty phosphatase, putative	0.0693	0.2194	0.4675
Toxoplasma gondii	hypothetical protein	0.0058	0.0107	0.3217
Trypanosoma brucei	DNA polymerase eta, putative	0.0077	0.0167	0.0157
Echinococcus granulosus	hypothetical protein	0.012	0.031	0.0271
Echinococcus multilocularis	conserved hypothetical protein	0.012	0.031	0.0271
Echinococcus multilocularis	potassium voltage gated channel subfamily D	0.012	0.031	0.0271
Echinococcus granulosus	cyclic nucleotide gated cation channel alpha 3	0.012	0.031	0.0271
Treponema pallidum	penicillin-binding protein (pbp-2)	0.0197	0.0563	1
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0033	0.0023
Brugia malayi	hypothetical protein	0.0173	0.0485	0.0475
Loa Loa (eye worm)	hypothetical protein	0.012	0.031	0.03
Trichomonas vaginalis	DNA polymerase IV / kappa, putative	0.0046	0.0067	0.0058
Trypanosoma brucei	mitochondrial DNA polymerase beta	0.0361	0.1102	0.1093
Loa Loa (eye worm)	hypothetical protein	0.012	0.031	0.03
Schistosoma mansoni	high voltage-activated calcium channel Cav2A	0.012	0.031	0.0278
Leishmania major	DNA polymerase kappa, putative	0.0046	0.0067	0.0057
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0092	0.0219	0.018
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0073	0.0156	0.0146
Brugia malayi	Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog	0.012	0.031	0.03
Loa Loa (eye worm)	hypothetical protein	0.012	0.031	0.03
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0118	0.0302	0.0302
Echinococcus multilocularis	voltage dependent L type calcium channel subunit	0.012	0.031	0.0271
Schistosoma mansoni	patched 1	0.1262	0.4067	0.4047
Echinococcus multilocularis	cyclic nucleotide gated cation channel	0.012	0.031	0.0271
Schistosoma mansoni	voltage-gated potassium channel	0.012	0.031	0.0278
Echinococcus granulosus	potassium voltage gated channel subfamily A	0.012	0.031	0.0271
Trypanosoma brucei	DNA polymerase IV, putative	0.0046	0.0067	0.0057
Schistosoma mansoni	cellular tumor antigen P53	0.0052	0.0086	0.0053
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease	0.004	0.0046	0.0036
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.012	0.031	0.0278
Brugia malayi	Voltage-gated calcium channel, alpha subunit	0.012	0.031	0.03
Schistosoma mansoni	voltage-gated potassium channel	0.012	0.031	0.0278
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0046	0.0067	0.0057
Echinococcus granulosus	geminin	0.0164	0.0454	0.0416
Echinococcus granulosus	tumor protein p63	0.0355	0.1084	0.1049
Onchocerca volvulus		0.0099	0.0241	0.3949
Echinococcus granulosus	voltage dependent calcium channel	0.012	0.031	0.0271
Schistosoma mansoni	ryanodine receptor related	0.012	0.031	0.0278
Echinococcus granulosus	two pore calcium channel protein 2	0.012	0.031	0.0271
Trypanosoma brucei	DNA polymerase kappa, putative	0.0046	0.0067	0.0057
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0092	0.0219	0.0209
Trypanosoma cruzi	cysteine peptidase, putative	0.0073	0.0156	0.0146
Loa Loa (eye worm)	hypothetical protein	0.012	0.031	0.03
Trypanosoma brucei	DNA polymerase kappa, putative	0.0046	0.0067	0.0057
Echinococcus granulosus	neutral alpha glucosidase AB	0.0038	0.004	0.0001
Loa Loa (eye worm)	ImpB/MucB/SamB family protein	0.0046	0.0067	0.0057
Mycobacterium leprae	PROBABLE BIFUNCTIONAL MEMBRANE-ASSOCIATED PENICILLIN-BINDING PROTEIN 1A/1B PONA2 (MUREIN POLYMERASE) [INCLUDES: PENICILLIN-INSEN	0.0109	0.0274	0.4857
Schistosoma mansoni	ap endonuclease	0.004	0.0046	0.0013
Leishmania major	calcium channel protein, putative,ion transporter, putative	0.012	0.031	0.03
Schistosoma mansoni	transient receptor potential channel	0.012	0.031	0.0278
Brugia malayi	Transient-receptor-potential like protein	0.012	0.031	0.03
Echinococcus granulosus	dna polymerase kappa	0.0046	0.0067	0.0027
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	0.012	0.031	1
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0088	0.0078
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0092	0.0219	0.0187
Chlamydia trachomatis	transglycolase/transpeptidase	0.0026	0	0.5
Mycobacterium tuberculosis	Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed))	0.0046	0.0067	0.1237
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.012	0.031	0.0271
Echinococcus granulosus	TRP transient receptor potential channel	0.012	0.031	0.0271
Echinococcus multilocularis	transient receptor potential cation channel	0.012	0.031	0.0271
Echinococcus multilocularis	terminal deoxycytidyl transferase rev1	0.0046	0.0067	0.0027
Trypanosoma brucei	DNA polymerase beta thumb, putative	0.0051	0.0082	0.0072
Echinococcus granulosus	lysosomal alpha glucosidase	0.0171	0.0479	0.0441
Trichomonas vaginalis	3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative	0.1439	0.4646	1
Schistosoma mansoni	voltage-gated potassium channel	0.012	0.031	0.0278
Echinococcus granulosus	transient receptor potential cation channel	0.012	0.031	0.0271
Entamoeba histolytica	exodeoxyribonuclease III, putative	0.004	0.0046	0.0029
Mycobacterium ulcerans	bifunctional penicillin-binding protein 1A/1B PonA1	0.0197	0.0563	0.0563
Leishmania major	aldehyde dehydrogenase, mitochondrial precursor	0.0118	0.0302	0.0292
Echinococcus multilocularis	ryanodine receptor 44f	0.012	0.031	0.0271
Loa Loa (eye worm)	hypothetical protein	0.0249	0.0733	0.0724
Loa Loa (eye worm)	hypothetical protein	0.0077	0.0167	0.0157
Echinococcus granulosus	voltage dependent calcium channel type d subunit\|voltage dependent calcium channel\|voltage dependent L type calcium channel subu	0.012	0.031	0.0271
Schistosoma mansoni	hyperpolarization activated cyclic nucleotide-gated potassium channel	0.012	0.031	0.0278
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.0051	0.0082	0.0072
Schistosoma mansoni	vesicular amine transporter	0.012	0.031	0.0278
Onchocerca volvulus		0.012	0.031	0.5656
Echinococcus granulosus	Potassium voltage gated channel protein Shaw	0.012	0.031	0.0271
Echinococcus multilocularis	hydroxymethylglutaryl coenzyme A reductase	0.3066	1	1
Schistosoma mansoni	hypothetical protein	0.0051	0.0082	0.0049
Echinococcus granulosus	transient receptor potential cation channel	0.012	0.031	0.0271
Echinococcus multilocularis	aldehyde dehydrogenase, mitochondrial	0.0118	0.0302	0.0263
Brugia malayi	cation channel family protein	0.012	0.031	0.03
Schistosoma mansoni	transient receptor potential cation channel subfamily m member	0.012	0.031	0.0278
Toxoplasma gondii	peptidylprolyl isomerase	0.0039	0.0043	0.1106
Schistosoma mansoni	voltage-gated potassium channel	0.012	0.031	0.0278
Loa Loa (eye worm)	hypothetical protein	0.3066	1	1
Schistosoma mansoni	voltage-gated cation channel	0.012	0.031	0.0278
Leishmania major	alpha glucosidase II subunit, putative	0.0038	0.004	0.003
Toxoplasma gondii	3'5'-cyclic nucleotide phosphodiesterase domain-containing protein	0.012	0.031	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0073	0.0156	0.0146
Trypanosoma cruzi	mitochondrial DNA polymerase beta, putative	0.0361	0.1102	0.1093
Leishmania major	apurinic/apyrimidinic endonuclease-redox protein	0.004	0.0046	0.0036
Echinococcus multilocularis	TRP (transient receptor potential) channel	0.012	0.031	0.0271
Schistosoma mansoni	voltage-gated potassium channel	0.012	0.031	0.0278
Schistosoma mansoni	voltage-gated potassium channel	0.012	0.031	0.0278
Schistosoma mansoni	voltage-dependent calcium channel	0.012	0.031	0.0278
Trypanosoma brucei	DNA polymerase kappa, putative	0.0046	0.0067	0.0057
Trypanosoma cruzi	cysteine peptidase, putative	0.0073	0.0156	0.0146
Echinococcus multilocularis	transient receptor potential cation channel	0.012	0.031	0.0271
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0118	0.0302	0.0302
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0092	0.0219	0.0187
Schistosoma mansoni	calcium-activated potassium channel	0.012	0.031	0.0278
Echinococcus multilocularis	potassium voltage gated channel subfamily C	0.012	0.031	0.0271
Echinococcus multilocularis	lysosomal alpha glucosidase	0.0171	0.0479	0.0441
Brugia malayi	ImpB/MucB/SamB family protein	0.0046	0.0067	0.0057
Brugia malayi	Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog	0.012	0.031	0.03
Loa Loa (eye worm)	hypothetical protein	0.012	0.031	0.03
Echinococcus multilocularis	protein dispatched 1	0.1262	0.4067	0.4043
Echinococcus multilocularis	tumor protein p63	0.0355	0.1084	0.1049
Echinococcus multilocularis	potassium voltage gated channel protein	0.012	0.031	0.0271
Echinococcus multilocularis	geminin	0.0164	0.0454	0.0416
Trichomonas vaginalis	rotamase, putative	0.004	0.0046	0.0013
Echinococcus granulosus	two pore calcium channel protein 1	0.012	0.031	0.0271
Treponema pallidum	exodeoxyribonuclease (exoA)	0.004	0.0046	0.0814
Schistosoma mansoni	hyperpolarization activated cyclic nucleotide-gated potassium channel	0.012	0.031	0.0278
Echinococcus granulosus	aldehyde dehydrogenase mitochondrial	0.0118	0.0302	0.0263
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0092	0.0219	0.018
Trypanosoma brucei	DNA polymerase kappa, putative	0.0046	0.0067	0.0057
Loa Loa (eye worm)	voltage-gated potassium channel	0.012	0.031	0.03
Schistosoma mansoni	rotamase	0.004	0.0046	0.0013
Mycobacterium tuberculosis	Conserved hypothetical protein	0.019	0.054	1
Schistosoma mansoni	voltage-gated potassium channel	0.012	0.031	0.0278
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0073	0.0156	0.0146
Schistosoma mansoni	hydroxymethylglutaryl-CoA reductase (NADPH)	0.3066	1	1
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0046	0.0067	0.1237
Trypanosoma cruzi	inositol 1,4,5-trisphosphate receptor, putative	0.012	0.031	0.03
Loa Loa (eye worm)	voltage-dependent calcium channel	0.012	0.031	0.03
Trypanosoma brucei	DNA polymerase kappa, putative	0.0032	0.002	0.001
Echinococcus granulosus	short transient receptor potential channel 6	0.012	0.031	0.0271
Trypanosoma cruzi	mitochondrial DNA polymerase beta, putative	0.0361	0.1102	0.1093
Echinococcus multilocularis	potassium:sodium hyperpolarization activated	0.012	0.031	0.0271
Loa Loa (eye worm)	hypothetical protein	0.012	0.031	0.03
Entamoeba histolytica	peptidyl-prolyl cis-trans isomerase, putative	0.0039	0.0043	0.0017
Schistosoma mansoni	survival motor neuron protein	0.0051	0.0082	0.0049
Trichomonas vaginalis	conserved hypothetical protein	0.1262	0.4067	0.8742
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0073	0.0156	0.0146
Echinococcus multilocularis	potassium voltage gated channel subfamily A	0.012	0.031	0.0271
Loa Loa (eye worm)	hypothetical protein	0.012	0.031	0.03
Mycobacterium ulcerans	DNA polymerase IV	0.0046	0.0067	0.0067
Schistosoma mansoni	DNA polymerase eta	0.0077	0.0167	0.0134
Brugia malayi	Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit	0.012	0.031	0.03
Echinococcus multilocularis	transient receptor potential cation channel	0.012	0.031	0.0271
Trypanosoma brucei	mitochondrial DNA polymerase beta-PAK	0.0171	0.0477	0.0467
Brugia malayi	latrophilin 2 splice variant baaae	0.0036	0.0033	0.0023
Loa Loa (eye worm)	hypothetical protein	0.012	0.031	0.03
Brugia malayi	voltage-dependent calcium channel	0.012	0.031	0.03
Trypanosoma brucei	DNA polymerase kappa, putative	0.0046	0.0067	0.0057
Echinococcus granulosus	potassium voltage gated channel protein	0.012	0.031	0.0271
Loa Loa (eye worm)	abnormal chemotaxis protein 14	0.1262	0.4067	0.4061
Echinococcus granulosus	terminal deoxycytidyl transferase rev1	0.0046	0.0067	0.0027
Echinococcus multilocularis	neutral alpha glucosidase AB	0.0038	0.004	0.0001
Schistosoma mansoni	aldehyde dehydrogenase	0.0118	0.0302	0.027
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.012	0.031	0.0278
Echinococcus granulosus	potassium channel KvQLT family member kqt 1	0.012	0.031	0.0271
Schistosoma mansoni	transient receptor potential cation channel subfamily m member	0.012	0.031	0.0278
Loa Loa (eye worm)	hypothetical protein	0.012	0.031	0.03
Schistosoma mansoni	inositol 145-trisphosphate receptor	0.012	0.031	0.0278
Entamoeba histolytica	dual specificity protein phosphatase, putative	0.0693	0.2194	1
Trypanosoma brucei	DNA polymerase IV, putative	0.0046	0.0067	0.0057
Echinococcus multilocularis	short transient receptor potential channel 6	0.012	0.031	0.0271
Entamoeba histolytica	deoxycytidyl transferase, putative	0.0046	0.0067	0.0126
Echinococcus granulosus	voltage gated potassium channel	0.012	0.031	0.0271
Schistosoma mansoni	voltage-gated potassium channel	0.012	0.031	0.0278
Onchocerca volvulus	Transient receptor potential cation channel trpm homolog	0.012	0.031	0.5656
Trichomonas vaginalis	ap endonuclease, putative	0.004	0.0046	0.0012
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.012	0.031	0.0278
Mycobacterium ulcerans	exodeoxyribonuclease III protein XthA	0.004	0.0046	0.0046
Schistosoma mansoni	high voltage-activated calcium channel Cav1	0.012	0.031	0.0278
Brugia malayi	Ryanodine Receptor TM 4-6 family protein	0.012	0.031	0.03
Brugia malayi	Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit	0.012	0.031	0.03
Brugia malayi	ion channel NompC	0.012	0.031	0.03

Activities

Activity type	Activity value	Assay description	Source	Reference
Activity (functional)	= 0	Antimaximal electroshock seizure (MES) activity in mice after peroral administration of 100 mg/kg of compound; 0/5	ChEMBL.	2891853
Control (functional)	= 106 %	3,4 -Dihydroxy phenylacetic acid (DOPAC) levels in mouse brain at 10 mg/kg dose.	ChEMBL.	2891853
Control (functional)	= 181 %	The homovanillic acid (HVA) levels in mouse brain at 10 mg/kg of dose.	ChEMBL.	2891853
Control (functional)	= 291 %	3,4 -Dihydroxy phenylacetic acid (DOPAC) levels in mouse brain at 50 mg/kg dose.	ChEMBL.	2891853
Control (functional)	= 335 %	The homovanillic acid (HVA) levels in mouse brain at 50 mg/kg of dose.	ChEMBL.	2891853
Inhibition (functional)	< 30 %	Antireserpine activity(RES) of mice after peroral administration of 50 mg/kg of compound; No inhibition	ChEMBL.	2891853
Inhibition (functional)	< 30 %	Antitremorine activity(TRM) of mice after peroral administration of 100 mg/kg of compound; No inhibition	ChEMBL.	2891853
Inhibition (functional)	= 31 %	Antiexploratory activity (EXPL) of mice determined by an antimex activity meter, 50 mg/kg of dose was administered perorally; Slight inhibition (31-50%)	ChEMBL.	2891853
Inhibition (functional)	= 31.9 %	Exploratory activity of mice determined by an antimex activity meter, 10 mg/kg of dose was administered perorally	ChEMBL.	2891853
Inhibition (functional)	= 36.1 %	Exploratory activity of mice determined by an antimex activity meter, 50 mg/kg of dose was administered perorally	ChEMBL.	2891853
Inhibition (functional)	= 72.5 %	Inhibition of apomorphine induced emesis in dogs at 1 mg/kg of dose.	ChEMBL.	2891853

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: 118294

Bibliographic References

1 literature reference was collected for this gene.

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Detailed information for compound 17219