Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | tubulin epsilon chain | 0.0812 | 0.4723 | 0.4723 |
Echinococcus granulosus | nAChR subunit | 0.0013 | 0.0012 | 0.0012 |
Plasmodium falciparum | tubulin gamma chain | 0.0812 | 0.4723 | 0.4723 |
Echinococcus granulosus | calcium transporting ATPase type 2C member | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | tubulin epsilon chain | 0.0812 | 0.4723 | 0.4723 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0812 | 0.4723 | 0.4723 |
Brugia malayi | Tubulin gamma chain | 0.0812 | 0.4723 | 0.4723 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0013 | 0.0012 | 0.0012 |
Schistosoma mansoni | tubulin subunit delta | 0.0353 | 0.2014 | 0.2014 |
Echinococcus granulosus | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0014 | 0.0016 | 0.0016 |
Trypanosoma cruzi | alpha tubulin, putative | 0.102 | 0.5949 | 0.5949 |
Schistosoma mansoni | nAChR subunit | 0.0013 | 0.0012 | 0.0012 |
Trichomonas vaginalis | cation-transporting ATPase fungi, putative | 0.0014 | 0.0016 | 0.0016 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase 1 | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | tubulin alpha chain | 0.102 | 0.5949 | 0.5949 |
Trypanosoma brucei | tubulin delta chain | 0.0353 | 0.2014 | 0.2014 |
Giardia lamblia | Plasma membrane calcium-transporting ATPase 2 | 0.0014 | 0.0016 | 0.0016 |
Trypanosoma brucei | epsilon tubulin | 0.0812 | 0.4723 | 0.4723 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | tubulin beta chain | 0.0353 | 0.2014 | 0.2005 |
Schistosoma mansoni | ATPase | 0.0014 | 0.0016 | 0.0016 |
Echinococcus multilocularis | tubulin alpha chain | 0.102 | 0.5949 | 0.5949 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0021 | 0.0057 | 0.0057 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0013 | 0.0012 | 0.0012 |
Trypanosoma cruzi | tubulin delta chain | 0.0353 | 0.2014 | 0.2014 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0353 | 0.2014 | 0.2014 |
Schistosoma mansoni | ATPase | 0.0014 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | tubulin gamma chain | 0.0812 | 0.4723 | 0.4717 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0284 | 0.161 | 0.1597 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0013 | 0.0012 | 0.0012 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0026 | 0.0026 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.046 | 0.2644 | 0.2644 |
Brugia malayi | tubulin alpha-2 chain | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0014 | 0.0016 | 0.0016 |
Trypanosoma brucei | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Toxoplasma gondii | tubulin/FtsZ family, GTPase domain-containing protein | 0.0353 | 0.2014 | 0.2014 |
Echinococcus granulosus | sarco:endoplasmic reticulum calcium ATPase | 0.0014 | 0.0016 | 0.0016 |
Schistosoma mansoni | transmemberane protein | 0.0021 | 0.0057 | 0.0057 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0013 | 0.0012 | 0.0012 |
Toxoplasma gondii | tubulin/FtsZ family, GTPase domain-containing protein | 0.0353 | 0.2014 | 0.2014 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0131 | 0.0119 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0013 | 0.0012 | 0.0012 |
Giardia lamblia | Alpha-tubulin | 0.102 | 0.5949 | 0.5949 |
Mycobacterium leprae | cell division protein FtsZ | 0.0353 | 0.2014 | 1 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.046 | 0.2644 | 0.2644 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0013 | 0.0012 | 0.0012 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0013 | 0.0012 | 0.0012 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0013 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0221 | 0.021 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0013 | 0.0012 | 0.0012 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0013 | 0.0012 | 0.0012 |
Plasmodium vivax | tubulin alpha chain, putative | 0.102 | 0.5949 | 0.5943 |
Schistosoma mansoni | tubulin subunit alpha | 0.0353 | 0.2014 | 0.2014 |
Trypanosoma cruzi | plasma membrane Ca2+ ATPase | 0.0014 | 0.0016 | 0.0016 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0013 | 0.0012 | 0.0012 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0353 | 0.2014 | 0.2014 |
Mycobacterium tuberculosis | Cell division protein FtsZ | 0.0353 | 0.2014 | 1 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.102 | 0.5949 | 0.5949 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0013 | 0.0012 | 0.0012 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0013 | 0.0012 | 0.0012 |
Brugia malayi | Amyloid A4 extracellular domain containing protein | 0.0626 | 0.3628 | 0.3628 |
Trypanosoma brucei | beta tubulin | 0.0812 | 0.4723 | 0.4723 |
Toxoplasma gondii | P-type ATPase4, putative | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | tubulin alpha 1C chain | 0.102 | 0.5949 | 0.5949 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0013 | 0.0012 | 0.0012 |
Echinococcus multilocularis | tubulin alpha 3 chain | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.161 | 0.161 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0013 | 0.0012 | 0.0012 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.102 | 0.5949 | 0.5949 |
Schistosoma mansoni | alzheimer's disease beta-amyloid related | 0.0228 | 0.1282 | 0.1282 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0284 | 0.161 | 0.161 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0013 | 0.0012 | 0.0012 |
Echinococcus granulosus | tubulin alpha chain | 0.102 | 0.5949 | 0.5949 |
Echinococcus multilocularis | nervana 2 | 0.0021 | 0.0057 | 0.0057 |
Brugia malayi | Tubulin beta chain | 0.046 | 0.2644 | 0.2644 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.0716 | 0.0705 |
Echinococcus granulosus | tubulin alpha chain | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | cation-transporting ATPase, putative | 0.0014 | 0.0016 | 0.0016 |
Echinococcus multilocularis | tubulin alpha chain | 0.102 | 0.5949 | 0.5949 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0812 | 0.4723 | 0.4723 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0092 | 0.008 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Plasmodium falciparum | tubulin delta chain, putative | 0.0353 | 0.2014 | 0.2014 |
Plasmodium falciparum | tubulin epsilon chain, putative | 0.0812 | 0.4723 | 0.4723 |
Leishmania major | vacuolar-type Ca2 -ATPase, putative | 0.0014 | 0.0016 | 0.0016 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Echinococcus multilocularis | nervana 2 | 0.0021 | 0.0057 | 0.0057 |
Schistosoma mansoni | tubulin subunit beta | 0.0353 | 0.2014 | 0.2014 |
Trichomonas vaginalis | tubulin, putative | 0.0353 | 0.2014 | 0.2014 |
Brugia malayi | alpha-tubulin | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.102 | 0.5949 | 0.5949 |
Trypanosoma cruzi | Calcium ATPase SERCA-like | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0013 | 0.0012 | 0.0012 |
Brugia malayi | Cation transporter family protein | 0.0013 | 0.0012 | 0.0012 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0014 | 0.0016 | 0.0016 |
Schistosoma mansoni | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Entamoeba histolytica | tubulin alpha chain, putative | 0.102 | 0.5949 | 0.5943 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0026 | 0.0026 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Loa Loa (eye worm) | Na,K-ATPase alpha subunit | 0.0014 | 0.0016 | 0.0004 |
Trypanosoma cruzi | epsilon tubulin, putative | 0.0812 | 0.4723 | 0.4723 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0208 | 0.1161 | 0.1151 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0016 | 0.0004 |
Giardia lamblia | Epsilon tubulin | 0.0353 | 0.2014 | 0.2014 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0013 | 0.0012 | 0.0012 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.102 | 0.5949 | 0.5949 |
Entamoeba histolytica | tubulin gamma chain | 0.0812 | 0.4723 | 0.4715 |
Onchocerca volvulus | 0.0014 | 0.0016 | 0.0017 | |
Echinococcus multilocularis | tubulin subunit TubB | 0.102 | 0.5949 | 0.5949 |
Loa Loa (eye worm) | tubulin alpha chain | 0.102 | 0.5949 | 0.5944 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0013 | 0.0012 | 0.0012 |
Trypanosoma cruzi | plasma membrane Ca2+ ATPase | 0.0014 | 0.0016 | 0.0016 |
Entamoeba histolytica | tubulin alpha-1 chain | 0.102 | 0.5949 | 0.5943 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0012 | 0.0006 | 0.0006 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0092 | 0.0092 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0131 | 0.0131 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.0812 | 0.4723 | 0.4723 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0026 | 0.0026 |
Echinococcus granulosus | tubulin alpha 3 chain | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.161 | 0.161 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.046 | 0.2644 | 0.2644 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0013 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.102 | 0.5949 | 0.5944 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0012 | 0.0006 | 0.0006 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0013 | 0.0012 | 0.0012 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0021 | 0.0057 | 0.0057 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0013 | 0.0012 | 0.0012 |
Schistosoma mansoni | nAChR subunit | 0.0013 | 0.0012 | 0.0012 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.102 | 0.5949 | 0.5949 |
Plasmodium vivax | delta tubulin, putative | 0.0353 | 0.2014 | 0.2001 |
Brugia malayi | Tubulin beta chain | 0.0353 | 0.2014 | 0.2014 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.102 | 0.5949 | 0.5949 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0016 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0057 | 0.0045 |
Schistosoma mansoni | sodium / potassium ATPase beta chain | 0.0021 | 0.0057 | 0.0057 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0013 | 0.0012 | 0.0012 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0092 | 0.0092 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0013 | 0.0012 | 0.0012 |
Trypanosoma brucei | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0013 | 0.0012 | 0.0012 |
Schistosoma mansoni | tubulin subunit alpha | 0.102 | 0.5949 | 0.5949 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0013 | 0.0012 | 0.0012 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | alpha-tubulin isotype 2 | 0.0668 | 0.387 | 0.3863 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.102 | 0.5949 | 0.5949 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Echinococcus granulosus | tubulin alpha 3 chain | 0.102 | 0.5949 | 0.5949 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0026 | 0.0026 |
Echinococcus multilocularis | tubulin alpha chain | 0.102 | 0.5949 | 0.5949 |
Echinococcus granulosus | peroxisome assembly protein 26 | 0.102 | 0.5949 | 0.5949 |
Brugia malayi | Tubulin alpha chain | 0.102 | 0.5949 | 0.5949 |
Echinococcus granulosus | tubulin alpha | 0.0812 | 0.4723 | 0.4723 |
Loa Loa (eye worm) | alpha-tubulin | 0.102 | 0.5949 | 0.5944 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0026 | 0.0026 |
Toxoplasma gondii | tubulin/FtsZ family, GTPase domain-containing protein | 0.0812 | 0.4723 | 0.4723 |
Toxoplasma gondii | alpha-tubulin I, putative | 0.102 | 0.5949 | 0.5949 |
Loa Loa (eye worm) | hypothetical protein | 0.0494 | 0.2845 | 0.2836 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0013 | 0.0012 | 0.0012 |
Echinococcus multilocularis | tubulin alpha 1C chain | 0.102 | 0.5949 | 0.5949 |
Schistosoma mansoni | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0013 | 0.0012 | 0.0012 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0021 | 0.0057 | 0.0057 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0013 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | tubulin alpha-2 chain | 0.102 | 0.5949 | 0.5944 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0013 | 0.0012 | 0.0012 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.0668 | 0.387 | 0.387 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0013 | 0.0012 | 0.0012 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.161 | 0.161 |
Echinococcus granulosus | tubulin gamma 1 chain | 0.0812 | 0.4723 | 0.4723 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0021 | 0.0057 | 0.0057 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0013 | 0.0012 | 0.0012 |
Echinococcus multilocularis | tubulin gamma 1 chain | 0.0812 | 0.4723 | 0.4723 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0026 | 0.0014 |
Trypanosoma brucei | tubulin gamma chain | 0.0812 | 0.4723 | 0.4723 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0021 | 0.0057 | 0.0057 |
Echinococcus granulosus | tubulin delta chain | 0.0353 | 0.2014 | 0.2014 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.102 | 0.5949 | 0.5949 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.0221 | 0.0221 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.046 | 0.2644 | 0.2644 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Brugia malayi | tubulin alpha chain - mouse | 0.102 | 0.5949 | 0.5949 |
Giardia lamblia | Delta tubulin | 0.0353 | 0.2014 | 0.2014 |
Trypanosoma brucei | alpha tubulin, putative | 0.046 | 0.2644 | 0.2644 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0026 | 0.0026 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.102 | 0.5949 | 0.5949 |
Echinococcus granulosus | tubulin subunit TubB | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.161 | 0.161 |
Echinococcus multilocularis | hypothetical protein | 0.102 | 0.5949 | 0.5949 |
Leishmania major | epsilon tubulin, putative | 0.0812 | 0.4723 | 0.4723 |
Echinococcus multilocularis | nAChR subunit | 0.0013 | 0.0012 | 0.0012 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase, putative | 0.0014 | 0.0016 | 0.0016 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0092 | 0.0092 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.102 | 0.5949 | 0.5949 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0013 | 0.0012 | 0.0012 |
Plasmodium vivax | tubulin alpha chain, putative | 0.102 | 0.5949 | 0.5943 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0013 | 0.0012 | 0.0012 |
Trypanosoma brucei | epsilon tubulin | 0.0812 | 0.4723 | 0.4723 |
Schistosoma mansoni | tubulin subunit epsilon | 0.0812 | 0.4723 | 0.4723 |
Onchocerca volvulus | 0.0021 | 0.0057 | 0.0172 | |
Schistosoma mansoni | nAChR subunit | 0.0013 | 0.0012 | 0.0012 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0013 | 0.0012 | 0.0012 |
Echinococcus granulosus | nervana 2 | 0.0021 | 0.0057 | 0.0057 |
Loa Loa (eye worm) | hypothetical protein | 0.0668 | 0.387 | 0.3863 |
Brugia malayi | Tubulin alpha chain | 0.0353 | 0.2014 | 0.2014 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0116 | 0.0619 | 0.0609 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0013 | 0.0012 | 0.0012 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0284 | 0.161 | 0.1597 |
Brugia malayi | MH2 domain containing protein | 0.0116 | 0.0619 | 0.0619 |
Leishmania major | hypothetical protein, conserved | 0.0027 | 0.0092 | 0.0092 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0013 | 0.0012 | 0.0012 |
Echinococcus granulosus | nervana 2 | 0.0021 | 0.0057 | 0.0057 |
Schistosoma mansoni | nAChR subunit | 0.0013 | 0.0012 | 0.0012 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.102 | 0.5949 | 0.5949 |
Trypanosoma brucei | zeta tubulin, putative | 0.0353 | 0.2014 | 0.2014 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0013 | 0.0012 | 0.0012 |
Echinococcus granulosus | tubulin alpha chain | 0.102 | 0.5949 | 0.5949 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase 2 | 0.0014 | 0.0016 | 0.0016 |
Wolbachia endosymbiont of Brugia malayi | cell division protein FtsZ | 0.0353 | 0.2014 | 0.5 |
Schistosoma mansoni | tubulin subunit alpha | 0.102 | 0.5949 | 0.5949 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0026 | 0.0026 |
Treponema pallidum | cell division protein FtsZ | 0.0353 | 0.2014 | 1 |
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.0021 | 0.0057 | 0.0057 |
Schistosoma mansoni | nAChR subunit | 0.0013 | 0.0012 | 0.0012 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0026 | 0.0026 |
Echinococcus multilocularis | nervana 2 | 0.0021 | 0.0057 | 0.0057 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.0221 | 0.021 |
Echinococcus granulosus | tubulin alpha 1C chain | 0.102 | 0.5949 | 0.5949 |
Echinococcus multilocularis | tubulin alpha 1C chain | 0.102 | 0.5949 | 0.5949 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0668 | 0.387 | 0.3863 |
Echinococcus multilocularis | tubulin delta chain | 0.0353 | 0.2014 | 0.2014 |
Schistosoma mansoni | tubulin subunit gamma | 0.0812 | 0.4723 | 0.4723 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0131 | 0.0131 |
Trichomonas vaginalis | tubulin, putative | 0.046 | 0.2644 | 0.2644 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0013 | 0.0012 | 0.0012 |
Echinococcus multilocularis | peroxisome assembly protein 26 | 0.102 | 0.5949 | 0.5949 |
Plasmodium falciparum | alpha tubulin 2 | 0.102 | 0.5949 | 0.5949 |
Toxoplasma gondii | alpha tubulin TUBA1 | 0.102 | 0.5949 | 0.5949 |
Plasmodium vivax | tubulin gamma chain, putative | 0.0812 | 0.4723 | 0.4715 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0092 | 0.0092 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0036 | 0.0036 |
Trypanosoma cruzi | epsilon tubulin, putative | 0.0812 | 0.4723 | 0.4723 |
Echinococcus multilocularis | tubulin alpha chain | 0.102 | 0.5949 | 0.5949 |
Schistosoma mansoni | nAChR subunit | 0.0013 | 0.0012 | 0.0012 |
Schistosoma mansoni | nAChR subunit | 0.0013 | 0.0012 | 0.0012 |
Echinococcus granulosus | nervana 2 | 0.0021 | 0.0057 | 0.0057 |
Brugia malayi | Tubulin alpha-2 chain | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | tubulin, putative | 0.046 | 0.2644 | 0.2644 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0013 | 0.0012 | 0.0012 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0013 | 0.0012 | 0.0012 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0014 | 0.0016 | 0.0016 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.161 | 0.161 |
Echinococcus multilocularis | nervana 2 | 0.0021 | 0.0057 | 0.0057 |
Trypanosoma brucei | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Trypanosoma cruzi | tubulin gamma chain | 0.0812 | 0.4723 | 0.4723 |
Echinococcus multilocularis | tubulin alpha | 0.0812 | 0.4723 | 0.4723 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0013 | 0.0012 | 0.0012 |
Brugia malayi | Cation transporter family protein | 0.0013 | 0.0012 | 0.0012 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0139 | 0.0754 | 0.369 |
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.0021 | 0.0057 | 0.0057 |
Trichomonas vaginalis | cation-transporting ATPase, putative | 0.0014 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0116 | 0.0619 | 0.0609 |
Echinococcus granulosus | nervana 2 | 0.0021 | 0.0057 | 0.0057 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0027 | 0.0092 | 0.0076 |
Leishmania major | delta tubulin, putative | 0.0353 | 0.2014 | 0.2014 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.0013 | 0.0012 | 0.0012 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0013 | 0.0012 | 0.0012 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0092 | 0.0092 |
Onchocerca volvulus | 0.0021 | 0.0057 | 0.0172 | |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0013 | 0.0012 | 0.0012 |
Echinococcus multilocularis | sarco:endoplasmic reticulum calcium ATPase | 0.0014 | 0.0016 | 0.0016 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0027 | 0.0092 | 0.0092 |
Loa Loa (eye worm) | hypothetical protein | 0.0561 | 0.324 | 0.3232 |
Loa Loa (eye worm) | tubulin alpha-3 chain | 0.0561 | 0.324 | 0.3232 |
Echinococcus multilocularis | calcium transporting ATPase type 2C member | 0.0014 | 0.0016 | 0.0016 |
Giardia lamblia | Alpha-tubulin | 0.102 | 0.5949 | 0.5949 |
Toxoplasma gondii | calcium-translocating P-type ATPase, PMCA-type protein | 0.0014 | 0.0016 | 0.0016 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0013 | 0.0012 | 0.0012 |
Plasmodium falciparum | alpha tubulin 1 | 0.102 | 0.5949 | 0.5949 |
Leishmania major | gamma-tubulin | 0.0812 | 0.4723 | 0.4723 |
Echinococcus granulosus | plasma membrane calcium transporting ATPase 2 | 0.0014 | 0.0016 | 0.0016 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0353 | 0.2014 | 0.2014 |
Trypanosoma brucei | zeta tubulin | 0.0353 | 0.2014 | 0.2014 |
Brugia malayi | Na,K-ATPase alpha subunit | 0.0014 | 0.0016 | 0.0016 |
Echinococcus multilocularis | tubulin alpha 3 chain | 0.102 | 0.5949 | 0.5949 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0013 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0026 | 0.0014 |
Schistosoma mansoni | tubulin subunit alpha | 0.102 | 0.5949 | 0.5949 |
Brugia malayi | Cation transporter family protein | 0.0013 | 0.0012 | 0.0012 |
Leishmania major | vacuolar-type Ca2 -ATPase, putative | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0021 | 0.0057 | 0.0057 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0006 | 0.0006 |
Trypanosoma cruzi | tubulin delta chain | 0.0353 | 0.2014 | 0.2014 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.161 | 0.161 |
Echinococcus granulosus | tubulin alpha chain | 0.102 | 0.5949 | 0.5949 |
Loa Loa (eye worm) | alpha-tubulin | 0.102 | 0.5949 | 0.5944 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0057 | 0.0045 |
Toxoplasma gondii | sarco/endoplasmic reticulum Ca2+-ATPase | 0.0014 | 0.0016 | 0.0016 |
Giardia lamblia | Gamma tubulin | 0.0812 | 0.4723 | 0.4723 |
Trichomonas vaginalis | cation-transporting ATPase, putative | 0.0014 | 0.0016 | 0.0016 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0027 | 0.0092 | 0.0092 |
Onchocerca volvulus | 0.046 | 0.2644 | 1 | |
Trypanosoma brucei | epsilon tubulin | 0.0812 | 0.4723 | 0.4723 |
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.0021 | 0.0057 | 0.0057 |
Echinococcus multilocularis | Tetracycline resistance leader peptide, TetL | 0.0014 | 0.0016 | 0.0016 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.102 | 0.5949 | 0.5949 |
Brugia malayi | Cell division protein ftsZ | 0.0353 | 0.2014 | 0.2014 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.0221 | 0.0221 |
Mycobacterium ulcerans | cell division protein FtsZ | 0.0353 | 0.2014 | 1 |
Plasmodium vivax | tubulin epsilon chain, putative | 0.0812 | 0.4723 | 0.4715 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.046 | 0.2644 | 0.2644 |
Echinococcus multilocularis | sodium:potassium transporting ATPase subunit | 0.0021 | 0.0057 | 0.0057 |
Trypanosoma cruzi | zeta tubulin, putative | 0.0353 | 0.2014 | 0.2014 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.161 | 0.161 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0026 | 0.0026 |
Leishmania major | zeta tubulin, putative | 0.0353 | 0.2014 | 0.2014 |
Brugia malayi | Tubulin alpha-2 chain | 0.102 | 0.5949 | 0.5949 |
Loa Loa (eye worm) | tubulin alpha chain | 0.102 | 0.5949 | 0.5944 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.161 | 0.161 |
Schistosoma mansoni | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Loa Loa (eye worm) | hypothetical protein | 0.0265 | 0.1498 | 0.1489 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0353 | 0.2014 | 0.2014 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.102 | 0.5949 | 0.5949 |
Echinococcus multilocularis | tubulin alpha chain | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | tubulin beta-1 chain, putative | 0.0353 | 0.2014 | 0.2014 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0026 | 0.0026 |
Echinococcus granulosus | sodium:potassium transporting ATPase subunit | 0.0021 | 0.0057 | 0.0057 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.0561 | 0.324 | 0.324 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0668 | 0.387 | 0.3863 |
Leishmania major | calcium-translocating P-type ATPase | 0.0014 | 0.0016 | 0.0016 |
Trypanosoma brucei | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0014 | 0.0016 | 0.0016 |
Schistosoma mansoni | Na+/K+ transporting ATPase subunit alpha | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.102 | 0.5949 | 0.5949 |
Trypanosoma cruzi | zeta tubulin, putative | 0.0353 | 0.2014 | 0.2014 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0013 | 0.0012 | 0.0012 |
Plasmodium falciparum | non-SERCA-type Ca2+ -transporting P-ATPase | 0.0014 | 0.0016 | 0.0016 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | = 40 % | Inhibition of recombinant SphK2 expressed in baculovirus infected Sf9 cells using D-erythro-sphingosine as substrate and [32gammaP]ATP assessed as residual activity at 10 uM by scintillation counting | ChEMBL. | 22321213 |
Activity (binding) | = 79 % | Inhibition of recombinant SphK1 expressed in baculovirus infected Sf9 cells using D-erythro-sphingosine as substrate and [32gammaP]ATP assessed as residual activity at 10 uM by scintillation counting | ChEMBL. | 22321213 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.