Detailed information for compound 1722374

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 405.533 | Formula: C25H31N3O2
  • H donors: 0 H acceptors: 2 LogP: 4.99 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC1=CCCC(C1/C=C/c1onc(c1)C(=O)N1CCN(CC1)c1ccccc1)(C)C
  • InChi: 1S/C25H31N3O2/c1-19-8-7-13-25(2,3)22(19)12-11-21-18-23(26-30-21)24(29)28-16-14-27(15-17-28)20-9-5-4-6-10-20/h4-6,8-12,18,22H,7,13-17H2,1-3H3/b12-11+
  • InChiKey: LKAMVAXWRGYUEG-VAWYXSNFSA-N  

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0024 0.0024
Brugia malayi PAS domain containing protein 0.0049 0.0264 0.0423
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0024 0.0059
Leishmania major alpha tubulin 0.0586 0.461 0.7391
Onchocerca volvulus 0.0087 0.0567 0.1119
Echinococcus granulosus Tubulin alpha 1 chain 0.0586 0.461 0.461
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0036 0.0154 0.0981
Leishmania major cytochrome p450-like protein 0.0088 0.0576 0.0923
Plasmodium vivax hypothetical protein, conserved 0.0079 0.0508 0.0814
Mycobacterium tuberculosis Probable reductase 0.0234 0.1758 0.4436
Schistosoma mansoni tubulin subunit beta 0.0788 0.6238 0.6238
Plasmodium vivax ataxin-2 like protein, putative 0.0085 0.0551 0.0884
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0198 0.1465 0.1465
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0184 0.1352 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0198 0.1465 0.2349
Trypanosoma cruzi PAB1-binding protein , putative 0.0085 0.0551 0.0884
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0026 0.0029
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0247 0.036
Brugia malayi Tubulin alpha chain 0.0184 0.1352 0.2167
Trichomonas vaginalis tubulin, putative 0.0239 0.1802 0.2862
Loa Loa (eye worm) cytochrome P450 0.0049 0.0266 0.0296
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.005 0.0275 0.0404
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0635 0.0984
Schistosoma mansoni transcription factor LCR-F1 0.0042 0.0203 0.0203
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0154 0.0247
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0049 0.0266 0.0672
Mycobacterium tuberculosis Cell division protein FtsZ 0.0184 0.1352 0.3412
Plasmodium vivax tubulin beta chain, putative 0.0788 0.6238 1
Entamoeba histolytica tubulin family protein 0.0788 0.6238 1
Giardia lamblia Beta tubulin 0.0788 0.6238 1
Echinococcus multilocularis tubulin alpha chain 0.0586 0.461 0.461
Echinococcus granulosus bloom syndrome protein 0.0047 0.0247 0.0247
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0049 0.0266 0.0672
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0026 0.0029
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0198 0.1465 0.1465
Plasmodium vivax delta tubulin, putative 0.0184 0.1352 0.2167
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0023 0.0037
Echinococcus granulosus single minded 2 0.004 0.0189 0.0189
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0023 0.0023
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0023 0.0026
Trichomonas vaginalis tubulin beta chain, putative 0.0586 0.461 0.7381
Trypanosoma cruzi PAB1-binding protein , putative 0.0085 0.0551 0.0884
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0635 0.0984
Trypanosoma brucei tubulin delta chain 0.0184 0.1352 0.2167
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0268 0.2034 0.2264
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.026 0.1969 1
Echinococcus multilocularis lamin dm0 0.0087 0.0567 0.0567
Echinococcus multilocularis tubulin alpha 3 chain 0.0586 0.461 0.461
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0347 0.2675 0.4267
Echinococcus multilocularis glycine receptor subunit beta 0.0198 0.1465 0.1465
Loa Loa (eye worm) hypothetical protein 0.0079 0.0508 0.0565
Leishmania major beta tubulin 0.0788 0.6238 1
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0049 0.0266 0.0427
Loa Loa (eye worm) hypothetical protein 0.0175 0.1281 0.1426
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0161 0.0221
Loa Loa (eye worm) tubulin alpha 2 0.0403 0.3125 0.3478
Onchocerca volvulus 0.0198 0.1465 0.3594
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2034 0.3236
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0023 0.0023
Onchocerca volvulus 0.0096 0.0642 0.1326
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0096 0.0642 0.1029
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0024 0.0038
Brugia malayi hypoxia-induced factor 1 0.0152 0.1097 0.1759
Schistosoma mansoni lamin 0.0087 0.0567 0.0567
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0036 0.0154 0.5
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0049 0.0266 0.0672
Loa Loa (eye worm) hypothetical protein 0.0096 0.0642 0.0715
Mycobacterium tuberculosis Probable lipase LipE 0.0079 0.0508 0.1281
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0024 0.0038
Brugia malayi Cation transporter family protein 0.0198 0.1465 0.2349
Trypanosoma cruzi trypanothione reductase, putative 0.0036 0.0154 0.0247
Brugia malayi Cytochrome P450 family protein 0.0172 0.1256 0.2013
Schistosoma mansoni tubulin subunit beta 0.0788 0.6238 0.6238
Schistosoma mansoni hypothetical protein 0.0358 0.2762 0.2762
Echinococcus multilocularis beta tubulin 0.0788 0.6238 0.6238
Echinococcus multilocularis Tubulin alpha 1 chain 0.0586 0.461 0.461
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0041 0.0196 0.0314
Toxoplasma gondii beta-1 tubulin, putative 0.0788 0.6238 1
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0036 0.0154 0.0154
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0635 0.0984
Echinococcus granulosus tubulin subunit TubB 0.0586 0.461 0.461
Brugia malayi beta-lactamase family protein 0.0079 0.0508 0.0814
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0154 0.0247
Mycobacterium ulcerans lipase LipD 0.0079 0.0508 0.3645
Brugia malayi serine/threonine-protein kinase plk-2 0.0095 0.0635 0.1017
Loa Loa (eye worm) MH2 domain-containing protein 0.0125 0.0875 0.0974
Echinococcus multilocularis Tubulin beta 2C chain 0.0788 0.6238 0.6238
Echinococcus multilocularis Tubulin beta 2C chain 0.0788 0.6238 0.6238
Schistosoma mansoni calcium-activated potassium channel 0.0286 0.2183 0.2183
Onchocerca volvulus 0.0079 0.0508 0.0955
Trichomonas vaginalis tubulin alpha chain, putative 0.0239 0.1802 0.2862
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0198 0.1465 0.2349
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0023 0.0026
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0049 0.0266 0.0672
Leishmania major beta tubulin 0.0788 0.6238 1
Schistosoma mansoni calcium-activated potassium channel 0.0358 0.2762 0.2762
Brugia malayi Intermediate filament tail domain containing protein 0.0087 0.0567 0.0909
Echinococcus granulosus lamin dm0 0.0087 0.0567 0.0567
Giardia lamblia Epsilon tubulin 0.0184 0.1352 0.2138
Plasmodium vivax tubulin gamma chain, putative 0.0423 0.3287 0.527
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0049 0.0266 0.0672
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0024 0.0038
Brugia malayi hypothetical protein 0.0275 0.2092 0.3354
Trypanosoma cruzi cytochrome P450, putative 0.0088 0.0576 0.0923
Loa Loa (eye worm) hypothetical protein 0.0065 0.0389 0.0433
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0026 0.0026
Echinococcus multilocularis nAChR subunit 0.0102 0.069 0.069
Loa Loa (eye worm) hypothetical protein 0.0102 0.069 0.0768
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0154 0.0247
Loa Loa (eye worm) hypothetical protein 0.0198 0.1465 0.1631
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0036 0.0154 0.0247
Leishmania major beta tubulin 0.0788 0.6238 1
Loa Loa (eye worm) acetylcholine receptor protein 0.0096 0.0642 0.0715
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0164 0.1191 0.1326
Trypanosoma cruzi trypanothione reductase, putative 0.0102 0.0696 0.1115
Leishmania major alpha tubulin 0.0586 0.461 0.7391
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0198 0.1465 0.1465
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0024 0.0038
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0102 0.0696 0.1756
Schistosoma mansoni tubulin subunit beta 0.0788 0.6238 0.6238
Echinococcus granulosus nAChR subunit 0.0102 0.069 0.069
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0026 0.0041
Trypanosoma brucei hypothetical protein, conserved 0.0079 0.0508 0.0814
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0049 0.0266 0.0672
Trichomonas vaginalis DNA helicase recq1, putative 0.0047 0.0247 0.0359
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0042 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0096 0.0642 0.0715
Schistosoma mansoni acetylcholine receptor-related 0.0096 0.0642 0.0642
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0247 0.036
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0023 0.0023
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0096 0.0642 0.0642
Onchocerca volvulus Putative nachr subunit 0.0198 0.1465 0.3594
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0049 0.0266 0.0672
Mycobacterium ulcerans beta-lactamase 0.0079 0.0508 0.3645
Echinococcus multilocularis tubulin alpha 1C chain 0.0586 0.461 0.461
Echinococcus multilocularis tumor protein p63 0.0381 0.2947 0.2947
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0161 0.0257
Schistosoma mansoni tubulin subunit beta 0.0184 0.1352 0.1352
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0198 0.1465 0.1465
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0049 0.0266 0.1827
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0049 0.0266 0.1827
Brugia malayi Cytochrome P450 family protein 0.0088 0.0576 0.0923
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0023 0.0026
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0198 0.1465 0.1465
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0102 0.069 0.069
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.1191 0.1191
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0041 0.0196 0.0278
Plasmodium falciparum tubulin beta chain 0.0788 0.6238 1
Loa Loa (eye worm) alpha-tubulin 0.0586 0.461 0.5131
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0024 0.0026
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0036 0.0154 0.0247
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0024 0.0038
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0198 0.1465 0.1465
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0161 0.0221
Leishmania major DNA polymerase eta, putative 0.0019 0.0024 0.0038
Schistosoma mansoni nAChR subunit 0.0096 0.0642 0.0642
Plasmodium falciparum glutathione reductase 0.0102 0.0696 0.1115
Loa Loa (eye worm) hypothetical protein 0.0057 0.0327 0.0364
Brugia malayi Pre-SET motif family protein 0.0061 0.0361 0.0579
Leishmania major beta tubulin 0.0788 0.6238 1
Trichomonas vaginalis tubulin epsilon chain, putative 0.0586 0.461 0.7381
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0198 0.1465 0.2349
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0023 0.0037
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0102 0.069 0.1106
Echinococcus granulosus microtubule associated protein 2 0.0803 0.6361 0.6361
Echinococcus granulosus peroxisome assembly protein 26 0.0586 0.461 0.461
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0096 0.0642 0.0642
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0049 0.0266 0.0672
Schistosoma mansoni lamin 0.0087 0.0567 0.0567
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0036 0.0154 0.0247
Schistosoma mansoni DNA helicase recq5 0.0019 0.0023 0.0023
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0024 0.0024
Echinococcus multilocularis lamin 0.0087 0.0567 0.0567
Loa Loa (eye worm) tubulin gamma chain 0.0423 0.3287 0.3658
Schistosoma mansoni neurotransmitter gated ion channel 0.0096 0.0642 0.0642
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0023 0.0023
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0198 0.1465 0.2349
Brugia malayi Tubulin gamma chain 0.0423 0.3287 0.527
Loa Loa (eye worm) tubulin alpha 2 0.0164 0.119 0.1324
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.1191 0.1191
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0023 0.0037
Brugia malayi hypothetical protein 0.0096 0.0642 0.1029
Brugia malayi MH2 domain containing protein 0.0125 0.0875 0.1402
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0161 0.0161
Echinococcus multilocularis tubulin gamma 1 chain 0.0423 0.3287 0.3287
Toxoplasma gondii alpha-tubulin I, putative 0.0586 0.461 0.7391
Leishmania major alpha tubulin 0.0586 0.461 0.7391
Brugia malayi Tubulin beta chain 0.0184 0.1352 0.2167
Loa Loa (eye worm) tubulin beta chain 0.0184 0.1352 0.1504
Trypanosoma cruzi tubulin gamma chain 0.0423 0.3287 0.527
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0042 0.0205 0.0205
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0234 0.1758 0.8761
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0036 0.0154 0.0154
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0024 0.0024
Schistosoma mansoni alpha glucosidase 0.0036 0.0161 0.0161
Schistosoma mansoni cytochrome P450 0.0049 0.0266 0.0266
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0023 0.0023
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.0023 0.0023
Onchocerca volvulus 0.0198 0.1465 0.3594
Echinococcus granulosus expressed protein 0.0377 0.2917 0.2917
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0049 0.0266 0.1827
Trichomonas vaginalis tubulin, putative 0.0788 0.6238 1
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2034 0.3236
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0049 0.0266 0.1827
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0024 0.0038
Loa Loa (eye worm) tubulin beta-2A chain 0.0788 0.6238 0.6942
Trichomonas vaginalis mercuric reductase, putative 0.0036 0.0154 0.021
Echinococcus granulosus survival motor neuron protein 1 0.0275 0.2092 0.2092
Leishmania major alpha tubulin 0.0586 0.461 0.7391
Loa Loa (eye worm) hypothetical protein 0.0079 0.0508 0.0565
Loa Loa (eye worm) acetyltransferase 0.0318 0.244 0.2715
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0023 0.0023
Loa Loa (eye worm) tubulin alpha-2 chain 0.0586 0.461 0.5131
Schistosoma mansoni nAChR subunit 0.0198 0.1465 0.1465
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0026
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0032 0.0123 0.0198
Echinococcus granulosus nAChR subunit 0.0198 0.1465 0.1465
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0154 0.0247
Echinococcus granulosus tubulin subunit beta 0.0788 0.6238 0.6238
Schistosoma mansoni hypothetical protein 0.0049 0.0266 0.0266
Leishmania major beta tubulin 0.0788 0.6238 1
Loa Loa (eye worm) hypothetical protein 0.0198 0.1465 0.1631
Schistosoma mansoni ets-related 0.023 0.1723 0.1723
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.0023 0.0026
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0096 0.0642 0.1029
Trypanosoma cruzi tubulin delta chain 0.0184 0.1352 0.2167
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0024 0.0024
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0094 0.0623 0.0999
Loa Loa (eye worm) hypothetical protein 0.0096 0.0642 0.0715
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0234 0.1758 0.4436
Echinococcus multilocularis small conductance calcium activated potassium 0.0358 0.2762 0.2762
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.007 0.0075
Loa Loa (eye worm) hypothetical protein 0.069 0.5446 0.6062
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0198 0.1465 0.1465
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0096 0.0642 0.0715
Echinococcus granulosus tubulin alpha chain 0.0586 0.461 0.461
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0026 0.0026
Echinococcus granulosus glycine receptor subunit alpha 1 0.0198 0.1465 0.1465
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0361 0.0361
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0423 0.3287 0.527
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0079 0.0508 0.0565
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0508 0.0779
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.012 0.0193
Toxoplasma gondii ABC1 family protein 0.0079 0.0508 0.0814
Echinococcus multilocularis thioredoxin glutathione reductase 0.0102 0.0696 0.0696
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0041 0.0196 0.0196
Brugia malayi hypothetical protein 0.0019 0.0023 0.0037
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0234 0.1758 0.4436
Echinococcus multilocularis Tubulin alpha 1 chain 0.0586 0.461 0.461
Loa Loa (eye worm) hypothetical protein 0.0096 0.0642 0.0715
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0026 0.0026
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0023 0.0023
Echinococcus granulosus intermediate filament protein 0.0087 0.0567 0.0567
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0046 0.0242 0.0269
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0198 0.1465 0.1465
Echinococcus granulosus tubulin alpha chain 0.0586 0.461 0.461
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0508 0.0779
Brugia malayi Glycosyl hydrolases family 31 protein 0.0164 0.1191 0.191
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0102 0.069 0.1106
Trypanosoma brucei alpha tubulin 0.0586 0.461 0.7391
Trypanosoma brucei glucosidase, putative 0.0036 0.0161 0.0257
Leishmania major beta tubulin 0.0788 0.6238 1
Treponema pallidum cell division protein FtsZ 0.0184 0.1352 1
Brugia malayi hypothetical protein 0.0123 0.0861 0.1381
Loa Loa (eye worm) hypothetical protein 0.0096 0.0642 0.0715
Brugia malayi Cytochrome P450 family protein 0.0049 0.0266 0.0427
Loa Loa (eye worm) hypothetical protein 0.0102 0.069 0.0768
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.1366 0.216
Trypanosoma brucei beta tubulin 0.0788 0.6238 1
Trichomonas vaginalis tubulin alpha chain, putative 0.0788 0.6238 1
Brugia malayi Tubulin beta-1 chain 0.0788 0.6238 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0079 0.0508 0.0508
Schistosoma mansoni tubulin subunit beta 0.0788 0.6238 0.6238
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0023 0.0038
Plasmodium falciparum ataxin-2 like protein, putative 0.0085 0.0551 0.0884
Loa Loa (eye worm) hypothetical protein 0.0135 0.0962 0.1071
Loa Loa (eye worm) hypothetical protein 0.0594 0.4671 0.5199
Loa Loa (eye worm) hypothetical protein 0.0198 0.1465 0.1631
Leishmania major beta tubulin 0.0788 0.6238 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0198 0.1465 0.2349
Brugia malayi Cation transporter family protein 0.0198 0.1465 0.2349
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0161 0.0258
Echinococcus granulosus GA binding protein alpha chain 0.0076 0.0478 0.0478
Schistosoma mansoni tubulin subunit beta 0.0788 0.6238 0.6238
Plasmodium vivax glutathione reductase, putative 0.0102 0.0696 0.1115
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.007 0.0112
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0161 0.0257
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0079 0.0508 0.3645
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0361 0.0361
Loa Loa (eye worm) CYP4Cod1 0.0088 0.0576 0.0641
Loa Loa (eye worm) cytochrome P450 family protein 0.0172 0.1256 0.1397
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0041 0.0196 0.0218
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0096 0.0642 0.1029
Loa Loa (eye worm) hypothetical protein 0.0079 0.0508 0.0565
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0079 0.0508 0.1281
Loa Loa (eye worm) hypothetical protein 0.0165 0.12 0.1336
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0508 0.0814
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0196 0.0314
Echinococcus granulosus tubulin alpha chain 0.0586 0.461 0.461
Echinococcus multilocularis Tubulin alpha 1 chain 0.0586 0.461 0.461
Loa Loa (eye worm) tubulin alpha chain 0.0586 0.461 0.5131
Schistosoma mansoni nAChR subunit 0.0096 0.0642 0.0642
Loa Loa (eye worm) follicle stimulating hormone receptor 0.048 0.3745 0.4168
Schistosoma mansoni kinase 0.0048 0.0257 0.0257
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0026 0.0078 0.0124
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0788 0.6238 0.6238
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0198 0.1465 0.1465
Loa Loa (eye worm) hypothetical protein 0.0198 0.1465 0.1631
Plasmodium falciparum glutathione reductase 0.0036 0.0154 0.0247
Brugia malayi beta-tubulin, identical 0.0788 0.6238 1
Trichomonas vaginalis tubulin beta chain, putative 0.0788 0.6238 1
Brugia malayi follicle stimulating hormone receptor 0.048 0.3745 0.6004
Onchocerca volvulus 0.0056 0.0317 0.0431
Mycobacterium ulcerans cell division protein FtsZ 0.0184 0.1352 1
Entamoeba histolytica tubulin family protein 0.0788 0.6238 1
Leishmania major beta tubulin 0.0788 0.6238 1
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0198 0.1465 0.1465
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0196 0.0278
Loa Loa (eye worm) hypothetical protein 0.0096 0.0642 0.0715
Loa Loa (eye worm) tubulin alpha chain 0.0586 0.461 0.5131
Leishmania major alpha tubulin 0.0586 0.461 0.7391
Giardia lamblia Beta tubulin 0.0788 0.6238 1
Toxoplasma gondii thioredoxin reductase 0.0102 0.0696 0.1115
Echinococcus multilocularis tubulin subunit beta 0.0788 0.6238 0.6238
Schistosoma mansoni DNA polymerase eta 0.0019 0.0024 0.0024
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0508 0.0508
Schistosoma mansoni alpha tubulin 0.0586 0.461 0.461
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0049 0.0266 0.0427
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0198 0.1465 0.1465
Loa Loa (eye worm) cytochrome P450 family protein 0.0088 0.0576 0.0641
Schistosoma mansoni blooms syndrome DNA helicase 0.0037 0.0167 0.0167
Schistosoma mansoni nAChR subunit 0.0198 0.1465 0.1465
Loa Loa (eye worm) hypothetical protein 0.0056 0.0317 0.0353
Echinococcus multilocularis dna polymerase eta 0.0019 0.0024 0.0024
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0023 0.0023
Trypanosoma cruzi beta tubulin, putative 0.0788 0.6238 1
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0049 0.0266 0.1827
Giardia lamblia Alpha-tubulin 0.0586 0.461 0.7381
Onchocerca volvulus 0.0239 0.1802 0.4521
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0205 0.0205
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0198 0.1465 0.1465
Giardia lamblia Alpha-tubulin 0.0586 0.461 0.7381
Plasmodium falciparum ataxin-2 like protein, putative 0.0085 0.0551 0.0884
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0038 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0102 0.069 0.0768
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0094 0.0623 0.0999
Echinococcus granulosus small conductance calcium activated potassium 0.0358 0.2762 0.2762
Schistosoma mansoni alpha-glucosidase 0.0141 0.1007 0.1007
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0318 0.244 0.244
Schistosoma mansoni intermediate filament proteins 0.0087 0.0567 0.0567
Schistosoma mansoni neurotransmitter gated ion channel 0.0102 0.069 0.069
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0026 0.0026
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0038 0.0174 0.0174
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0049 0.0266 0.1827
Trichomonas vaginalis tubulin epsilon chain, putative 0.0788 0.6238 1
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0198 0.1465 0.1465
Onchocerca volvulus 0.0087 0.0567 0.1119
Echinococcus multilocularis nAChR subunit 0.0198 0.1465 0.1465
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0094 0.0623 0.0966
Schistosoma mansoni microtubule-associated protein tau 0.0803 0.6361 0.6361
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0184 0.1352 0.2167
Brugia malayi beta-lactamase family protein 0.0079 0.0508 0.0814
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0024 0.0038
Trichomonas vaginalis set domain proteins, putative 0.0485 0.3791 0.6063
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0635 0.0984
Echinococcus granulosus tubulin alpha 0.0423 0.3287 0.3287
Loa Loa (eye worm) hypothetical protein 0.0096 0.0642 0.0715
Onchocerca volvulus 0.0485 0.3791 1
Echinococcus granulosus glycine receptor subunit alpha 1 0.0198 0.1465 0.1465
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0026 0.0026
Brugia malayi alpha-tubulin 0.0586 0.461 0.7391
Echinococcus granulosus tubulin delta chain 0.0184 0.1352 0.1352
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0024 0.0038
Mycobacterium tuberculosis Probable dehydrogenase 0.0234 0.1758 0.4436
Leishmania major trypanothione reductase 0.0102 0.0696 0.1115
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0049 0.0266 0.0427
Echinococcus granulosus lysosomal alpha glucosidase 0.0164 0.1191 0.1191
Trypanosoma brucei polo-like protein kinase 0.0095 0.0635 0.1017
Echinococcus multilocularis GA binding protein alpha chain 0.0076 0.0478 0.0478
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0154 0.0247
Brugia malayi hypothetical protein 0.0019 0.0023 0.0037
Trichomonas vaginalis tubulin, putative 0.0184 0.1352 0.2138
Brugia malayi Thioredoxin reductase 0.0102 0.0696 0.1115
Onchocerca volvulus 0.0175 0.1281 0.3086
Brugia malayi Cytochrome P450 family protein 0.0088 0.0576 0.0923
Onchocerca volvulus 0.0102 0.069 0.1458
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0198 0.1465 0.1631
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0102 0.069 0.069
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0049 0.0266 0.1827
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0049 0.0266 0.1827
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0023 0.0023
Trypanosoma brucei alpha tubulin 0.0586 0.461 0.7391
Plasmodium falciparum alpha tubulin 2 0.0586 0.461 0.7391
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0198 0.1465 0.1631
Plasmodium falciparum tubulin epsilon chain, putative 0.0423 0.3287 0.527
Echinococcus granulosus tubulin beta 1 chain 0.0788 0.6238 0.6238
Loa Loa (eye worm) hypothetical protein 0.0096 0.0642 0.0715
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0023 0.0023
Schistosoma mansoni DNA helicase recq1 0.0019 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0096 0.0642 0.0715
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0154 0.0247
Trichomonas vaginalis esterase, putative 0.0079 0.0508 0.0779
Loa Loa (eye worm) hypoxia-induced factor 1 0.0152 0.1097 0.1221
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0026
Leishmania major hypothetical protein, conserved 0.0085 0.0551 0.0884
Mycobacterium tuberculosis Probable lipase LipD 0.0079 0.0508 0.1281
Leishmania major alpha tubulin 0.0586 0.461 0.7391
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0198 0.1465 0.1465
Loa Loa (eye worm) hypothetical protein 0.0096 0.0642 0.0715
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0198 0.1465 0.1631
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0198 0.1465 0.1631
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0049 0.0266 0.1827
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.0023 0.0038
Trypanosoma brucei beta tubulin 0.0788 0.6238 1
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0198 0.1465 0.2349
Echinococcus granulosus Tubulin beta 2C chain 0.0788 0.6238 0.6238
Loa Loa (eye worm) hypothetical protein 0.0087 0.0567 0.0631
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0024 0.0059
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0049 0.0266 0.0672
Echinococcus granulosus lamin 0.0087 0.0567 0.0567
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0161 0.0221
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0023 0.0023
Entamoeba histolytica hypothetical protein 0.0042 0.0203 0.029
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0102 0.069 0.0768
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0036 0.0154 0.0247
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0041 0.0196 0.0314
Trichomonas vaginalis tubulin epsilon chain, putative 0.0184 0.1352 0.2138
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.0508 0.0779
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0049 0.0266 0.0672
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0508 0.0779
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0024 0.0038
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.007 0.0112
Brugia malayi hypothetical protein 0.0096 0.0642 0.1029
Echinococcus multilocularis 0.0049 0.0266 0.0266
Leishmania major cytochrome p450-like protein 0.0049 0.0266 0.0427
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0076 0.0478 0.0532
Loa Loa (eye worm) hypothetical protein 0.0033 0.0135 0.0151
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0049 0.0266 0.0672
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0049 0.0266 0.0672
Brugia malayi Fli-1 protein 0.023 0.1723 0.2763
Echinococcus granulosus tubulin gamma 1 chain 0.0423 0.3287 0.3287
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0024 0.0038
Loa Loa (eye worm) hypothetical protein 0.0037 0.017 0.0189
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0635 0.0984
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0049 0.0266 0.1827
Loa Loa (eye worm) hypothetical protein 0.0042 0.0205 0.0228
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0024 0.0038
Echinococcus granulosus thioredoxin glutathione reductase 0.0102 0.0696 0.0696
Trichomonas vaginalis tubulin epsilon chain, putative 0.0788 0.6238 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0079 0.0508 0.1281
Plasmodium falciparum histone acetyltransferase GCN5 0.0086 0.056 0.0898
Onchocerca volvulus 0.0056 0.0321 0.044
Echinococcus multilocularis tubulin delta chain 0.0184 0.1352 0.1352
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0036 0.0154 0.0247
Mycobacterium leprae Probable lipase LipE 0.0079 0.0508 0.1419
Loa Loa (eye worm) hypothetical protein 0.0085 0.0551 0.0614
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0635 0.0635
Loa Loa (eye worm) hypothetical protein 0.0079 0.0508 0.0565
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0426 0.3314 0.3689
Trichomonas vaginalis conserved hypothetical protein 0.0184 0.1352 0.2138
Loa Loa (eye worm) hypothetical protein 0.0198 0.1465 0.1631
Trypanosoma cruzi tubulin delta chain 0.0184 0.1352 0.2167
Entamoeba histolytica hypothetical protein 0.0102 0.069 0.1073
Loa Loa (eye worm) beta-tubulin 0.0788 0.6238 0.6942
Toxoplasma gondii alpha tubulin TUBA1 0.0586 0.461 0.7391
Echinococcus granulosus glycine receptor subunit beta 0.0198 0.1465 0.1465
Trichomonas vaginalis tubulin epsilon chain, putative 0.0586 0.461 0.7381
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.0023 0.0023
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0096 0.0642 0.1029
Loa Loa (eye worm) ACC-1 protein 0.0198 0.1465 0.1631
Entamoeba histolytica tubulin gamma chain 0.0423 0.3287 0.5252
Plasmodium vivax tubulin alpha chain, putative 0.0586 0.461 0.7391
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0041 0.0196 0.0278
Leishmania major DNA polymerase kappa, putative 0.0019 0.0024 0.0038
Leishmania major gamma-tubulin 0.0423 0.3287 0.527
Leishmania major beta tubulin 0.0788 0.6238 1
Leishmania major hypothetical protein, conserved 0.0079 0.0508 0.0814
Schistosoma mansoni hypothetical protein 0.0056 0.0321 0.0321
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0026
Onchocerca volvulus 0.0096 0.0642 0.1326
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0038 0.0174 0.0174
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0023 0.0023
Trypanosoma brucei cytochrome P450, putative 0.0088 0.0576 0.0923
Loa Loa (eye worm) hypothetical protein 0.0038 0.0176 0.0196
Schistosoma mansoni acetylcholine receptor subunit beta 0.0096 0.0642 0.0642
Brugia malayi Tubulin beta chain 0.0239 0.1802 0.2889
Onchocerca volvulus 0.0198 0.1465 0.3594
Brugia malayi hypothetical protein 0.0096 0.0642 0.1029
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.069 0.5446 0.8731
Trichomonas vaginalis tubulin alpha chain, putative 0.0239 0.1802 0.2862
Loa Loa (eye worm) hypothetical protein 0.0321 0.2459 0.2737
Mycobacterium tuberculosis Conserved protein 0.0079 0.0508 0.1281
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0041 0.0196 0.0314
Loa Loa (eye worm) hypothetical protein 0.0079 0.0508 0.0565
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0023 0.0023
Entamoeba histolytica hypothetical protein 0.0042 0.0203 0.029
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0198 0.1465 0.1631
Echinococcus granulosus tubulin alpha 3 chain 0.0586 0.461 0.461
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0036 0.0154 0.0388
Brugia malayi tubulin alpha-2 chain 0.0586 0.461 0.7391
Schistosoma mansoni cellular tumor antigen P53 0.0056 0.0317 0.0317
Giardia lamblia Beta tubulin 0.0788 0.6238 1
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1289 0.2037
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0154 0.0247
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0049 0.0266 0.0672
Loa Loa (eye worm) hypothetical protein 0.0586 0.461 0.5131
Echinococcus granulosus dna polymerase kappa 0.0019 0.0024 0.0024
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.1366 0.216
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0041 0.0196 0.0314
Echinococcus multilocularis glycine receptor subunit beta 0.0198 0.1465 0.1465
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0361 0.0361
Loa Loa (eye worm) hypothetical protein 0.004 0.0192 0.0214
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0096 0.0642 0.1029
Echinococcus granulosus beta tubulin 0.0788 0.6238 0.6238
Mycobacterium tuberculosis Probable hydrolase 0.0079 0.0508 0.1281
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0026
Giardia lamblia Delta tubulin 0.0184 0.1352 0.2138
Trypanosoma brucei beta tubulin 0.0423 0.3287 0.527
Loa Loa (eye worm) ACC-1 protein 0.0198 0.1465 0.1631
Mycobacterium ulcerans hypothetical protein 0.0079 0.0508 0.3645
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0023 0.0023
Leishmania major alpha tubulin 0.0586 0.461 0.7391
Trichomonas vaginalis tubulin beta chain, putative 0.0586 0.461 0.7381
Schistosoma mansoni nAChR subunit 0.0198 0.1465 0.1465
Loa Loa (eye worm) hypothetical protein 0.0198 0.1465 0.1631
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0096 0.0642 0.0642
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0635 0.0984
Trypanosoma cruzi epsilon tubulin, putative 0.0423 0.3287 0.527
Brugia malayi hypothetical protein 0.0085 0.0551 0.0884
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0023 0.0023
Brugia malayi tubulin alpha chain - mouse 0.0586 0.461 0.7391
Entamoeba histolytica recQ family helicase, putative 0.0025 0.007 0.0075
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0198 0.1465 0.1465
Schistosoma mansoni tubulin subunit alpha 0.0184 0.1352 0.1352
Plasmodium falciparum thioredoxin reductase 0.0036 0.0154 0.0247
Loa Loa (eye worm) hypothetical protein 0.0102 0.069 0.0768
Loa Loa (eye worm) GABA receptor subunit 0.0102 0.069 0.0768
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0023 0.0023
Brugia malayi PXA domain containing protein 0.0019 0.0023 0.0037
Brugia malayi hypothetical protein 0.0165 0.12 0.1924
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0049 0.0266 0.0427
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0361 0.0361
Echinococcus granulosus Tubulin beta 2C chain 0.0788 0.6238 0.6238
Echinococcus multilocularis tubulin alpha chain 0.0586 0.461 0.461
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0842 0.6673 0.6673
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0154 0.0247
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0506 0.3962 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0026
Loa Loa (eye worm) hypothetical protein 0.0347 0.2675 0.2977
Trichomonas vaginalis tubulin gamma chain, putative 0.0423 0.3287 0.5252
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0024 0.0038
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0096 0.0642 0.0715
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0023 0.0023
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0161 0.0161
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0343 0.0343
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0023 0.0023
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0161 0.0257
Brugia malayi hypothetical protein 0.0055 0.0309 0.0495
Loa Loa (eye worm) tubulin alpha 2 0.0403 0.3125 0.3478
Trypanosoma brucei zeta tubulin 0.0184 0.1352 0.2167
Trichomonas vaginalis tubulin gamma chain, putative 0.0788 0.6238 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0161 0.0221
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0096 0.0642 0.0642
Brugia malayi beta-lactamase 0.0079 0.0508 0.0814
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0161 0.0179
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0024 0.0038
Schistosoma mansoni ap endonuclease 0.0041 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0198 0.1465 0.1631
Schistosoma mansoni hypothetical protein 0.0038 0.0174 0.0174
Brugia malayi Bloom's syndrome protein homolog 0.0047 0.0247 0.0395
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0102 0.069 0.1106
Trichomonas vaginalis tubulin alpha chain, putative 0.0423 0.3287 0.5252
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0095 0.0635 0.1017
Loa Loa (eye worm) hypothetical protein 0.0198 0.1465 0.1631
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0361 0.0361
Loa Loa (eye worm) BEN-1 protein 0.0788 0.6238 0.6942
Schistosoma mansoni hypothetical protein 0.0042 0.0203 0.0203
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0041 0.0196 0.0196
Schistosoma mansoni survival motor neuron protein 0.0056 0.0321 0.0321
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0586 0.461 0.7381
Leishmania major beta tubulin 0.0788 0.6238 1
Loa Loa (eye worm) tubulin beta chain 0.0788 0.6238 0.6942
Echinococcus granulosus histone acetyltransferase KAT2B 0.0094 0.0623 0.0623
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0023 0.0023
Echinococcus granulosus glycine receptor subunit alpha 1 0.0198 0.1465 0.1465
Trypanosoma brucei zeta tubulin, putative 0.0184 0.1352 0.2167
Echinococcus granulosus alpha tubulin 0.0586 0.461 0.461
Mycobacterium tuberculosis Conserved protein 0.0079 0.0508 0.1281
Schistosoma mansoni tubulin subunit delta 0.0184 0.1352 0.1352
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0198 0.1465 0.2349
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0049 0.0266 0.1827
Echinococcus granulosus tubulin alpha 1C chain 0.0586 0.461 0.461
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0102 0.069 0.1106
Echinococcus multilocularis microtubule associated protein 2 0.0803 0.6361 0.6361
Echinococcus multilocularis musashi 0.0087 0.0567 0.0567
Echinococcus granulosus glycine receptor subunit beta 0.0198 0.1465 0.1465
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1289 0.2037
Onchocerca volvulus 0.0079 0.0508 0.0955
Toxoplasma gondii NADPH-glutathione reductase 0.0036 0.0154 0.0247
Trypanosoma brucei alpha tubulin 0.0586 0.461 0.7391
Loa Loa (eye worm) beta-lactamase 0.0079 0.0508 0.0565
Plasmodium falciparum tubulin gamma chain 0.0423 0.3287 0.527
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0095 0.0635 0.0635
Leishmania major beta tubulin 0.0788 0.6238 1
Leishmania major alpha tubulin 0.0586 0.461 0.7391
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0161 0.0221
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0049 0.0266 0.1827
Loa Loa (eye worm) tubulin beta-1 chain 0.0788 0.6238 0.6942
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0041 0.0196 0.0494
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0024 0.0038
Brugia malayi hypothetical protein 0.0042 0.0203 0.0326
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0023 0.0023
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0184 0.1352 0.2167
Echinococcus multilocularis tubulin alpha chain 0.0586 0.461 0.461
Brugia malayi hypothetical protein 0.0175 0.1281 0.2054
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0036 0.0154 0.0981
Giardia lamblia Kinase, PLK 0.0095 0.0635 0.0984
Schistosoma mansoni nAChR subunit 0.0198 0.1465 0.1465
Echinococcus multilocularis survival motor neuron protein 1 0.0275 0.2092 0.2092
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0264 0.0264
Loa Loa (eye worm) hypothetical protein 0.0198 0.1465 0.1631
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0023 0.0038
Schistosoma mansoni alpha tubulin 0.0586 0.461 0.461
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2034 0.3236
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0161 0.0221
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0635 0.0984
Loa Loa (eye worm) hypothetical protein 0.0403 0.3125 0.3478
Echinococcus multilocularis tubulin alpha 1C chain 0.0586 0.461 0.461
Entamoeba histolytica hypothetical protein 0.0042 0.0203 0.029
Echinococcus multilocularis tubulin alpha 0.0423 0.3287 0.3287
Brugia malayi Cell division protein ftsZ 0.0184 0.1352 0.2167
Echinococcus multilocularis bloom syndrome protein 0.0047 0.0247 0.0247
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.002 0.0026 0.0005
Plasmodium vivax tubulin epsilon chain, putative 0.0423 0.3287 0.527
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0198 0.1465 0.2349
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0095 0.0635 0.0635
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0154 0.0247
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0198 0.1465 0.1465
Echinococcus multilocularis tubulin alpha 3 chain 0.0586 0.461 0.461
Loa Loa (eye worm) hypothetical protein 0.0198 0.1465 0.1631
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0234 0.1758 0.4436
Trypanosoma brucei PAB1-binding protein , putative 0.0085 0.0551 0.0884
Entamoeba histolytica serine/threonine protein kinase, putative 0.0095 0.0635 0.0984
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0198 0.1465 0.2349
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0049 0.0266 0.1827
Leishmania major protein kinase, putative 0.0018 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0026
Loa Loa (eye worm) BEN-1 protein 0.0788 0.6238 0.6942
Trichomonas vaginalis tubulin gamma chain, putative 0.0184 0.1352 0.2138
Echinococcus granulosus Tubulin beta 2C chain 0.0788 0.6238 0.6238
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0042 0.0205 0.0205
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0198 0.1465 0.1465
Leishmania major cytochrome p450-like protein 0.0049 0.0266 0.0427
Brugia malayi intermediate filament protein 0.0087 0.0567 0.0909
Loa Loa (eye worm) hypothetical protein 0.0102 0.069 0.0768
Trypanosoma brucei unspecified product 0.0019 0.0024 0.0038
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0026
Trypanosoma cruzi alpha tubulin, putative 0.0586 0.461 0.7391
Loa Loa (eye worm) hypothetical protein 0.0151 0.1087 0.121
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0049 0.0266 0.0672
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0024 0.0024
Brugia malayi Tubulin alpha-2 chain 0.0586 0.461 0.7391
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.0508 0.0779
Brugia malayi excitatory GABA receptor EXP-1A 0.0198 0.1465 0.2349
Toxoplasma gondii beta tubulin 0.0788 0.6238 1
Echinococcus multilocularis tubulin beta 1 chain 0.0788 0.6238 0.6238
Trypanosoma brucei beta tubulin 0.0788 0.6238 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.002 0.0026 0.0005
Entamoeba histolytica acetyltransferase, GNAT family 0.0086 0.056 0.0864
Entamoeba histolytica tubulin alpha chain, putative 0.0586 0.461 0.7381
Echinococcus granulosus cytochrome P450 2K1 0.0049 0.0266 0.0266
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0049 0.0266 0.0672
Loa Loa (eye worm) hypothetical protein 0.0275 0.2092 0.2328
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0094 0.0623 0.0999
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0198 0.1465 0.1465
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0096 0.0642 0.1029
Schistosoma mansoni tubulin subunit alpha 0.0586 0.461 0.461
Onchocerca volvulus 0.0102 0.069 0.1458
Plasmodium vivax thioredoxin reductase, putative 0.0102 0.0696 0.1115
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0049 0.0266 0.0672
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0198 0.1465 0.1465
Trichomonas vaginalis tubulin gamma chain, putative 0.0423 0.3287 0.5252
Trichomonas vaginalis conserved hypothetical protein 0.0184 0.1352 0.2138
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0024 0.0038
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0023 0.0023
Leishmania major zeta tubulin, putative 0.0184 0.1352 0.2167
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0161 0.0221
Loa Loa (eye worm) LGC-31 protein 0.0198 0.1465 0.1631
Loa Loa (eye worm) thioredoxin reductase 0.0102 0.0696 0.0774
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0023 0.0023
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0023 0.0023
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0205 0.0205
Brugia malayi cytochrome P450 0.0049 0.0266 0.0427
Brugia malayi Tubulin alpha-2 chain 0.0586 0.461 0.7391
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0088 0.0576 0.4158
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0198 0.1465 0.1465
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0161 0.0221
Loa Loa (eye worm) hypothetical protein 0.0198 0.1465 0.1631
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0042 0.0203 0.0203
Onchocerca volvulus 0.0198 0.1465 0.3594
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0023 0.0023
Onchocerca volvulus Glucosylceramidase homolog 0.0176 0.1289 0.3108
Giardia lamblia Histone acetyltransferase GCN5 0.0086 0.056 0.0864
Schistosoma mansoni tubulin subunit alpha 0.0586 0.461 0.461
Loa Loa (eye worm) hypothetical protein 0.0198 0.1465 0.1631
Loa Loa (eye worm) hypothetical protein 0.0079 0.0508 0.0565
Trichomonas vaginalis tubulin beta chain, putative 0.0586 0.461 0.7381
Leishmania major beta tubulin 0.0788 0.6238 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0198 0.1465 0.2349
Leishmania major beta tubulin 0.0788 0.6238 1
Loa Loa (eye worm) hypothetical protein 0.0198 0.1465 0.1631
Brugia malayi PXA domain containing protein 0.0019 0.0023 0.0037
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0049 0.0266 0.1827
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0061 0.0361 0.0361
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.026 0.1969 0.4969
Loa Loa (eye worm) hypothetical protein 0.0198 0.1465 0.1631
Entamoeba histolytica hypothetical protein 0.0042 0.0203 0.029
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0056 0.0321 0.0514
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0023 0.0023
Echinococcus multilocularis tubulin subunit TubB 0.0586 0.461 0.461
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0036 0.0154 0.0247
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0024 0.0038
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0049 0.0266 0.1827
Brugia malayi hypothetical protein 0.0096 0.0642 0.1029
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0049 0.0266 0.0427
Loa Loa (eye worm) alpha-tubulin 0.0586 0.461 0.5131
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0041 0.02 0.0321
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0079 0.0508 0.0814
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1289 0.2037
Trichomonas vaginalis DNA helicase recq, putative 0.0047 0.0247 0.0359
Echinococcus multilocularis Tubulin beta 2C chain 0.0788 0.6238 0.6238
Echinococcus granulosus Tubulin beta 2C chain 0.0788 0.6238 0.6238
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0198 0.1465 0.2349
Schistosoma mansoni gabp alpha 0.0076 0.0478 0.0478
Onchocerca volvulus Serine\/threonine kinase homolog 0.0095 0.0635 0.1305
Loa Loa (eye worm) hypothetical protein 0.004 0.0192 0.0214
Leishmania major beta tubulin 0.0788 0.6238 1
Loa Loa (eye worm) tubulin beta-4 chain 0.0788 0.6238 0.6942
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0361 0.0579
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0161 0.0221
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0154 0.0247
Loa Loa (eye worm) fli-1 protein 0.023 0.1723 0.1918
Trypanosoma cruzi epsilon tubulin, putative 0.0423 0.3287 0.527
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0161 0.0257
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1289 0.2037
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0198 0.1465 0.2349
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.0023 0.0023
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0161 0.1034
Plasmodium falciparum thioredoxin reductase 0.0102 0.0696 0.1115
Trypanosoma cruzi zeta tubulin, putative 0.0184 0.1352 0.2167
Trichomonas vaginalis tubulin beta chain, putative 0.0239 0.1802 0.2862
Echinococcus multilocularis tubulin alpha chain 0.0586 0.461 0.461
Trichomonas vaginalis tubulin alpha chain, putative 0.0239 0.1802 0.2862
Loa Loa (eye worm) hypothetical protein 0.0198 0.1465 0.1631
Echinococcus granulosus tubulin epsilon chain 0.0423 0.3287 0.3287
Leishmania major epsilon tubulin, putative 0.0423 0.3287 0.527
Echinococcus multilocularis beta tubulin 0.0788 0.6238 0.6238
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0403 0.3125 0.4991
Onchocerca volvulus 0.0198 0.1465 0.3594
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0024 0.0038
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0036 0.0154 0.0247
Mycobacterium tuberculosis Probable oxidoreductase 0.026 0.1969 0.4969
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0049 0.0266 0.1827
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0023 0.0037
Echinococcus multilocularis tubulin alpha chain 0.0586 0.461 0.461
Leishmania major alpha tubulin 0.0586 0.461 0.7391
Giardia lamblia Gamma tubulin 0.0423 0.3287 0.5252
Mycobacterium tuberculosis Conserved protein 0.0079 0.0508 0.1281
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0087 0.0567 0.0631
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0096 0.0642 0.0642
Trypanosoma brucei alpha tubulin, putative 0.0239 0.1802 0.2889
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0049 0.0266 0.0672
Mycobacterium leprae conserved hypothetical protein 0.0079 0.0508 0.1419
Trichomonas vaginalis tubulin, putative 0.0239 0.1802 0.2862
Loa Loa (eye worm) hypothetical protein 0.0358 0.2762 0.3074
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0403 0.3125 0.3478
Onchocerca volvulus 0.0061 0.0361 0.0552
Echinococcus multilocularis beta LACTamase domain containing family member 0.0079 0.0508 0.0508
Leishmania major alpha tubulin 0.0586 0.461 0.7391
Brugia malayi Ets-domain containing protein 0.0076 0.0478 0.0766
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.026 0.1969 0.4969
Plasmodium vivax SET domain protein, putative 0.0061 0.0361 0.0579
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0038 0.0176 0.0196
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0023 0.0038
Brugia malayi Pre-SET motif family protein 0.0426 0.3314 0.5314
Loa Loa (eye worm) glutathione reductase 0.0102 0.0696 0.0774
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1289 0.2037
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0184 0.1352 0.2138
Onchocerca volvulus 0.0198 0.1465 0.3594
Trypanosoma brucei epsilon tubulin 0.0423 0.3287 0.527
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1289 0.2037
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0041 0.0196 0.0314
Schistosoma mansoni tubulin subunit epsilon 0.0423 0.3287 0.3287
Loa Loa (eye worm) hypothetical protein 0.1127 0.8985 1
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0049 0.0266 0.1827
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.0508 0.0508
Brugia malayi cytoplasmic intermediate filament protein 0.0046 0.0242 0.0388
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0036 0.0154 0.0247
Leishmania major delta tubulin, putative 0.0184 0.1352 0.2167
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0318 0.244 0.244
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0024 0.0038
Echinococcus multilocularis peroxisome assembly protein 26 0.0586 0.461 0.461
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0023 0.0038
Leishmania major alpha tubulin 0.0586 0.461 0.7391
Trypanosoma cruzi polo-like protein kinase, putative 0.0095 0.0635 0.1017
Brugia malayi glutathione reductase 0.0102 0.0696 0.1115
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0079 0.0508 0.1281
Echinococcus multilocularis hypothetical protein 0.0586 0.461 0.461
Trypanosoma cruzi zeta tubulin, putative 0.0184 0.1352 0.2167
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0198 0.1465 0.1465
Loa Loa (eye worm) intermediate filament protein 0.0087 0.0567 0.0631
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0154 0.0247
Loa Loa (eye worm) transcription factor SMAD2 0.0125 0.0875 0.0974
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0361 0.0361
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0036 0.0154 0.0247
Loa Loa (eye worm) tubulin alpha-3 chain 0.0347 0.2675 0.2977
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.0508 0.0814
Leishmania major beta tubulin 0.0788 0.6238 1
Giardia lamblia NADH oxidase lateral transfer candidate 0.0036 0.0154 0.021
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0036 0.0154 0.0154
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0024 0.0038
Echinococcus granulosus tubulin alpha chain 0.0586 0.461 0.461
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.005 0.0275 0.0404
Echinococcus granulosus Tubulin beta 2C chain 0.0788 0.6238 0.6238
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0024 0.0038
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2034 0.3236
Echinococcus multilocularis tubulin epsilon chain 0.0423 0.3287 0.3287
Trypanosoma brucei epsilon tubulin 0.0423 0.3287 0.527
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0198 0.1465 0.2349
Loa Loa (eye worm) hypothetical protein 0.0198 0.1465 0.1631
Loa Loa (eye worm) hypothetical protein 0.0198 0.1465 0.1631
Plasmodium vivax tubulin alpha chain, putative 0.0586 0.461 0.7391
Toxoplasma gondii cytochrome p450 superfamily protein 0.0049 0.0266 0.0427
Onchocerca volvulus 0.0095 0.0633 0.13
Leishmania major beta tubulin 0.0788 0.6238 1
Echinococcus granulosus Tubulin alpha 1 chain 0.0586 0.461 0.461
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0268 0.2034 0.3261
Schistosoma mansoni single-minded 0.0049 0.0264 0.0264
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0161 0.0257
Schistosoma mansoni tubulin subunit beta 0.0788 0.6238 0.6238
Echinococcus multilocularis expressed protein 0.0377 0.2917 0.2917
Echinococcus multilocularis Tubulin beta 2C chain 0.0788 0.6238 0.6238
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0036 0.0154 0.0247
Trypanosoma brucei alpha tubulin 0.0586 0.461 0.7391
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0023 0.0037
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0198 0.1465 0.1465
Schistosoma mansoni nAChR subunit 0.0198 0.1465 0.1465
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0198 0.1465 0.1465
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0041 0.0196 0.1298
Trichomonas vaginalis tubulin beta chain, putative 0.0586 0.461 0.7381
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0049 0.0266 0.1827
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2034 0.3236
Brugia malayi Cation transporter family protein 0.0198 0.1465 0.2349
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0049 0.0266 0.0672
Loa Loa (eye worm) hypothetical protein 0.0096 0.0642 0.0715
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.007 0.0112
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0161 0.0221
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0198 0.1465 0.1465
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0154 0.0247
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0049 0.0266 0.1827
Loa Loa (eye worm) hypothetical protein 0.0102 0.069 0.0768
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0198 0.1465 0.1631
Plasmodium falciparum tubulin delta chain, putative 0.0184 0.1352 0.2167
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0041 0.0196 0.0351
Trichomonas vaginalis tubulin beta chain, putative 0.0586 0.461 0.7381
Loa Loa (eye worm) hypothetical protein 0.0061 0.0361 0.0402
Echinococcus granulosus tubulin beta 4A class IVa 0.0788 0.6238 0.6238
Loa Loa (eye worm) hypothetical protein 0.0085 0.0554 0.0617
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0234 0.1758 0.4436
Trichomonas vaginalis glutathione reductase, putative 0.0036 0.0154 0.021
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0198 0.1465 0.2349
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0239 0.1802 0.2862
Plasmodium vivax tryptophan-rich antigen (Pv-fam-a) 0.0546 0.4285 0.6869
Schistosoma mansoni tubulin subunit alpha 0.0586 0.461 0.461
Schistosoma mansoni nAChR subunit 0.0198 0.1465 0.1465
Entamoeba histolytica tubulin alpha-1 chain 0.0586 0.461 0.7381
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0049 0.0266 0.0672
Loa Loa (eye worm) hypothetical protein 0.0102 0.069 0.0768
Trichomonas vaginalis bromodomain-containing protein, putative 0.0094 0.0623 0.0966
Echinococcus granulosus Tubulin alpha 1 chain 0.0586 0.461 0.461
Trypanosoma cruzi cytochrome P450, putative 0.0088 0.0576 0.0923
Brugia malayi acetyltransferase, GNAT family protein 0.0318 0.244 0.3912
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0038 0.0176 0.0176
Onchocerca volvulus 0.0096 0.0642 0.1326
Schistosoma mansoni alpha tubulin 0.0586 0.461 0.461
Echinococcus granulosus tubulin alpha 3 chain 0.0586 0.461 0.461
Trypanosoma brucei epsilon tubulin 0.0423 0.3287 0.527
Loa Loa (eye worm) RecQ helicase 0.0047 0.0247 0.0274
Echinococcus granulosus beta tubulin 0.0788 0.6238 0.6238
Echinococcus granulosus histone acetyltransferase KAT2B 0.0309 0.2368 0.2368
Leishmania major alpha tubulin 0.0586 0.461 0.7391
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0049 0.0266 0.0672
Trichomonas vaginalis tubulin beta chain, putative 0.0586 0.461 0.7381
Loa Loa (eye worm) hypothetical protein 0.0019 0.0024 0.0026
Echinococcus granulosus tumor protein p63 0.0381 0.2947 0.2947
Schistosoma mansoni alpha-glucosidase 0.0141 0.1007 0.1007
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0161 0.0161
Toxoplasma gondii LsmAD domain-containing protein 0.0085 0.0551 0.0884
Schistosoma mansoni neurotransmitter gated ion channel 0.0096 0.0642 0.0642
Trypanosoma brucei tubulin gamma chain 0.0423 0.3287 0.527
Toxoplasma gondii beta-tubulin, putative 0.0788 0.6238 1
Toxoplasma gondii exonuclease III APE 0.0041 0.0196 0.0314
Loa Loa (eye worm) cytochrome P450 family protein 0.0088 0.0576 0.0641
Echinococcus granulosus tubulin alpha 1C chain 0.0586 0.461 0.461
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2034 0.3236
Mycobacterium leprae cell division protein FtsZ 0.0184 0.1352 0.6376
Brugia malayi exodeoxyribonuclease III family protein 0.0041 0.0196 0.0314
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0038 0.0176 0.0282
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0026 0.0078 0.0124
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0095 0.0635 0.0706
Echinococcus granulosus dna polymerase eta 0.0019 0.0024 0.0024
Brugia malayi hypothetical protein 0.0096 0.0642 0.1029
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0161 0.0221
Trichomonas vaginalis ap endonuclease, putative 0.0041 0.0196 0.0278
Brugia malayi Tubulin alpha chain 0.0586 0.461 0.7391
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0023 0.0023
Plasmodium falciparum alpha tubulin 1 0.0586 0.461 0.7391
Leishmania major beta tubulin 0.0788 0.6238 1
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1289 0.2037
Mycobacterium ulcerans esterase/lipase LipP 0.0079 0.0508 0.3645
Schistosoma mansoni ap endonuclease 0.0041 0.0196 0.0196
Treponema pallidum exodeoxyribonuclease (exoA) 0.0041 0.0196 0.0351
Loa Loa (eye worm) hypothetical protein 0.0096 0.0642 0.0715
Schistosoma mansoni tubulin subunit gamma 0.0423 0.3287 0.3287
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0036 0.0154 0.0981
Loa Loa (eye worm) hypothetical protein 0.0096 0.0642 0.0715
Mycobacterium tuberculosis Probable esterase LipL 0.0079 0.0508 0.1281
Trypanosoma brucei beta tubulin 0.0788 0.6238 1
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0024 0.0038
Loa Loa (eye worm) hypothetical protein 0.0096 0.0642 0.0715
Leishmania major beta tubulin 0.0788 0.6238 1
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0049 0.0266 0.1827
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0198 0.1465 0.2349
Onchocerca volvulus 0.0079 0.0508 0.0955
Loa Loa (eye worm) hypothetical protein 0.0096 0.0642 0.0715
Trypanosoma brucei trypanothione reductase 0.0102 0.0696 0.1115
Echinococcus granulosus tubulin alpha chain 0.0586 0.461 0.461
Trypanosoma cruzi polo-like protein kinase, putative 0.0095 0.0635 0.1017
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0024 0.0038
Schistosoma mansoni nAChR subunit 0.0198 0.1465 0.1465
Echinococcus multilocularis Tubulin beta 2C chain 0.0788 0.6238 0.6238
Brugia malayi Ets-domain containing protein 0.0076 0.0478 0.0766

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.