TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 736.639 | Formula: C29H30F6N6O8S
H donors: 6 H acceptors: 7 LogP: 2.85 Rotable bonds: 15
Rule of 5 violations (Lipinski): 2
SMILES: [O-]C(=O)C(F)(F)F.[O-]C(=O)C(F)(F)F.O=C([C@H](NS(=O)(=O)c1cccc(c1)C(=[NH2+])N)COCc1ccccc1)NCc1ccc(cc1)C(=[NH2+])N
InChi: 1S/C25H28N6O4S.2C2HF3O2/c26-23(27)19-11-9-17(10-12-19)14-30-25(32)22(16-35-15-18-5-2-1-3-6-18)31-36(33,34)21-8-4-7-20(13-21)24(28)29;2*3-2(4,5)1(6)7/h1-13,22,31H,14-16H2,(H3,26,27)(H3,28,29)(H,30,32);2*(H,6,7)/t22-;;/m1../s1
InChiKey: KMPHTUIZFZPGAT-GJICFQLNSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	coagulation factor II (thrombin)	Starlite/ChEMBL	References
Homo sapiens	transmembrane protease, serine 6	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trichomonas vaginalis	tubulin epsilon chain, putative	0.0516	0.992	0.9915
Trypanosoma cruzi	epsilon tubulin, putative	0.0207	0.3147	0.2745
Echinococcus multilocularis	tubulin epsilon chain	0.0207	0.3147	0.3136
Echinococcus multilocularis	Tubulin alpha 1 chain	0.0215	0.3333	0.3325
Loa Loa (eye worm)	tubulin alpha 2	0.0125	0.1367	0.1332
Trichomonas vaginalis	tubulin gamma chain, putative	0.0207	0.3147	0.2722
Entamoeba histolytica	tubulin alpha chain, putative	0.0215	0.3333	0.2678
Trypanosoma brucei	alpha tubulin	0.0215	0.3333	0.2944
Echinococcus multilocularis	tubulin alpha chain	0.0215	0.3333	0.3325
Leishmania major	beta tubulin	0.0516	0.992	1
Loa Loa (eye worm)	branched-chain amino acid aminotransferase	0.0105	0.0924	0.0883
Trichomonas vaginalis	tubulin, putative	0.0117	0.1181	0.0633
Trypanosoma brucei	beta tubulin	0.0516	0.992	1
Schistosoma mansoni	tubulin subunit beta	0.0516	0.992	1
Echinococcus granulosus	tubulin alpha 3 chain	0.0215	0.3333	0.336
Brugia malayi	Cell division protein ftsZ	0.009	0.0585	0.0539
Plasmodium falciparum	tubulin beta chain	0.0516	0.992	1
Loa Loa (eye worm)	tubulin alpha 2	0.0125	0.1367	0.1332
Schistosoma mansoni	tubulin subunit alpha	0.0215	0.3333	0.3325
Trypanosoma cruzi	epsilon tubulin, putative	0.0207	0.3147	0.2745
Leishmania major	alpha tubulin	0.0215	0.3333	0.2944
Echinococcus multilocularis	beta tubulin	0.0516	0.992	1
Giardia lamblia	Beta tubulin	0.0516	0.992	1
Plasmodium vivax	tubulin beta chain, putative	0.0516	0.992	1
Echinococcus granulosus	tubulin alpha chain	0.0215	0.3333	0.336
Loa Loa (eye worm)	tubulin beta chain	0.009	0.0585	0.0539
Echinococcus granulosus	tubulin alpha chain	0.0215	0.3333	0.336
Brugia malayi	Pre-SET motif family protein	0.0456	0.8618	0.8681
Loa Loa (eye worm)	alpha-tubulin isotype 2	0.0125	0.1367	0.1332
Brugia malayi	Tubulin beta chain	0.0117	0.1181	0.1143
Loa Loa (eye worm)	tubulin beta-4 chain	0.0516	0.992	1
Toxoplasma gondii	tubulin/FtsZ family, GTPase domain-containing protein	0.009	0.0585	0.0539
Echinococcus granulosus	beta tubulin	0.0516	0.992	1
Plasmodium vivax	tubulin alpha chain, putative	0.0215	0.3333	0.3325
Leishmania major	beta tubulin	0.0516	0.992	1
Loa Loa (eye worm)	BEN-1 protein	0.0516	0.992	1
Entamoeba histolytica	tubulin gamma chain	0.0207	0.3147	0.2472
Echinococcus multilocularis	Tubulin alpha 1 chain	0.0215	0.3333	0.3325
Leishmania major	beta tubulin	0.0516	0.992	1
Echinococcus granulosus	tubulin alpha	0.0207	0.3147	0.3173
Leishmania major	alpha tubulin	0.0215	0.3333	0.2944
Giardia lamblia	Gamma tubulin	0.0207	0.3147	0.2745
Trichomonas vaginalis	tubulin beta chain, putative	0.0215	0.3333	0.2919
Loa Loa (eye worm)	alpha-tubulin	0.0215	0.3333	0.3325
Leishmania major	beta tubulin	0.0516	0.992	1
Schistosoma mansoni	tubulin subunit beta	0.0516	0.992	1
Schistosoma mansoni	tubulin subunit gamma	0.0207	0.3147	0.3136
Trypanosoma brucei	epsilon tubulin	0.0207	0.3147	0.2745
Plasmodium falciparum	tubulin gamma chain	0.0207	0.3147	0.2745
Loa Loa (eye worm)	tubulin gamma chain	0.0207	0.3147	0.3136
Echinococcus granulosus	tubulin beta 1 chain	0.0516	0.992	1
Leishmania major	gamma-tubulin	0.0207	0.3147	0.2745
Leishmania major	alpha tubulin	0.0215	0.3333	0.2944
Brugia malayi	Tubulin alpha chain	0.0215	0.3333	0.3325
Schistosoma mansoni	alpha tubulin	0.0215	0.3333	0.3325
Leishmania major	alpha tubulin	0.0215	0.3333	0.2944
Trichomonas vaginalis	tubulin alpha chain, putative	0.0516	0.992	0.9915
Plasmodium falciparum	alpha tubulin 2	0.0215	0.3333	0.2944
Leishmania major	beta tubulin	0.0516	0.992	1
Trichomonas vaginalis	tubulin beta chain, putative	0.0215	0.3333	0.2919
Leishmania major	beta tubulin	0.0516	0.992	1
Brugia malayi	tubulin alpha chain - mouse	0.0215	0.3333	0.3325
Trypanosoma brucei	branched-chain amino acid aminotransferase, putative	0.0105	0.0924	0.0363
Echinococcus granulosus	tubulin alpha 1C chain	0.0215	0.3333	0.336
Echinococcus granulosus	tubulin alpha chain	0.0215	0.3333	0.336
Loa Loa (eye worm)	tubulin alpha-3 chain	0.0098	0.0771	0.0728
Echinococcus granulosus	histone lysine methyltransferase setb	0.0065	0.0053	0.0053
Trichomonas vaginalis	tubulin alpha chain, putative	0.0117	0.1181	0.0633
Schistosoma mansoni	tubulin subunit beta	0.0516	0.992	1
Brugia malayi	beta-tubulin, identical	0.0516	0.992	1
Entamoeba histolytica	tubulin family protein	0.0516	0.992	1
Trichomonas vaginalis	tubulin, putative	0.0516	0.992	0.9915
Echinococcus granulosus	beta tubulin	0.0516	0.992	1
Echinococcus multilocularis	beta tubulin	0.0516	0.992	1
Leishmania major	alpha tubulin	0.0215	0.3333	0.2944
Echinococcus multilocularis	tubulin subunit TubB	0.0215	0.3333	0.3325
Onchocerca volvulus		0.0117	0.1181	0.1134
Leishmania major	beta tubulin	0.0516	0.992	1
Echinococcus multilocularis	tubulin, beta 4A class IVa	0.0516	0.992	1
Trichomonas vaginalis	branched-chain amino acid aminotransferase, putative	0.0105	0.0924	0.036
Leishmania major	beta tubulin	0.0516	0.992	1
Leishmania major	alpha tubulin	0.0215	0.3333	0.2944
Brugia malayi	tubulin alpha-2 chain	0.0215	0.3333	0.3325
Echinococcus multilocularis	tubulin alpha chain	0.0215	0.3333	0.3325
Plasmodium vivax	tubulin gamma chain, putative	0.0207	0.3147	0.3136
Leishmania major	alpha tubulin	0.0215	0.3333	0.2944
Echinococcus granulosus	tubulin subunit TubB	0.0215	0.3333	0.336
Loa Loa (eye worm)	hypothetical protein	0.0125	0.1367	0.1332
Toxoplasma gondii	tubulin/FtsZ family, GTPase domain-containing protein	0.009	0.0585	0.0539
Echinococcus granulosus	peroxisome assembly protein 26	0.0215	0.3333	0.336
Trichomonas vaginalis	tubulin epsilon chain, putative	0.0516	0.992	0.9915
Schistosoma mansoni	tubulin subunit epsilon	0.0207	0.3147	0.3136
Giardia lamblia	Alpha-tubulin	0.0215	0.3333	0.2944
Giardia lamblia	Beta tubulin	0.0516	0.992	1
Plasmodium falciparum	tubulin epsilon chain, putative	0.0207	0.3147	0.2745
Loa Loa (eye worm)	tubulin alpha chain	0.0215	0.3333	0.3325
Plasmodium vivax	delta tubulin, putative	0.009	0.0585	0.0539
Toxoplasma gondii	tubulin/FtsZ family, GTPase domain-containing protein	0.0207	0.3147	0.3136
Leishmania major	beta tubulin	0.0516	0.992	1
Echinococcus multilocularis	tubulin delta chain	0.009	0.0585	0.0539
Echinococcus granulosus	tubulin alpha 3 chain	0.0215	0.3333	0.336
Echinococcus granulosus	Tubulin beta 2C chain	0.0516	0.992	1
Treponema pallidum	cell division protein FtsZ	0.009	0.0585	0.5
Echinococcus multilocularis	Tubulin beta 2C chain	0.0516	0.992	1
Echinococcus multilocularis	hypothetical protein	0.0215	0.3333	0.3325
Trichomonas vaginalis	tubulin alpha-1 chain, putative	0.0117	0.1181	0.0633
Trypanosoma cruzi	beta tubulin, putative	0.0516	0.992	1
Toxoplasma gondii	alpha-tubulin I, putative	0.0215	0.3333	0.3325
Trichomonas vaginalis	tubulin alpha-1 chain, putative	0.0215	0.3333	0.2919
Echinococcus multilocularis	Tubulin alpha 1 chain	0.0215	0.3333	0.3325
Trypanosoma cruzi	alpha tubulin, putative	0.0215	0.3333	0.2944
Brugia malayi	Tubulin alpha-2 chain	0.0215	0.3333	0.3325
Echinococcus granulosus	Tubulin alpha 1 chain	0.0215	0.3333	0.336
Leishmania major	beta tubulin	0.0516	0.992	1
Trypanosoma brucei	epsilon tubulin	0.0207	0.3147	0.2745
Schistosoma mansoni	tubulin subunit alpha	0.009	0.0585	0.0539
Mycobacterium leprae	PROBABLE BRANCHED-CHAIN AMINO ACID TRANSAMINASE ILVE	0.0105	0.0924	1
Toxoplasma gondii	beta-1 tubulin, putative	0.0516	0.992	1
Trichomonas vaginalis	tubulin alpha-1 chain, putative	0.0125	0.1367	0.0831
Trichomonas vaginalis	tubulin gamma chain, putative	0.0516	0.992	0.9915
Plasmodium vivax	tubulin alpha chain, putative	0.0215	0.3333	0.3325
Echinococcus multilocularis	tubulin alpha chain	0.0215	0.3333	0.3325
Echinococcus granulosus	Tubulin beta 2C chain	0.0516	0.992	1
Brugia malayi	Tubulin gamma chain	0.0207	0.3147	0.3136
Echinococcus multilocularis	tubulin alpha chain	0.0215	0.3333	0.3325
Brugia malayi	Tubulin beta chain	0.009	0.0585	0.0539
Loa Loa (eye worm)	tubulin alpha-2 chain	0.0215	0.3333	0.3325
Trichomonas vaginalis	tubulin epsilon chain, putative	0.0215	0.3333	0.2919
Echinococcus granulosus	Tubulin alpha 1 chain	0.0215	0.3333	0.336
Trypanosoma brucei	branched-chain amino acid aminotransferase, putative	0.0105	0.0924	0.0363
Brugia malayi	Tubulin beta-1 chain	0.0516	0.992	1
Echinococcus multilocularis	tubulin gamma 1 chain	0.0207	0.3147	0.3136
Echinococcus multilocularis	tubulin alpha chain	0.0215	0.3333	0.3325
Echinococcus multilocularis	Tubulin beta 2C chain	0.0516	0.992	1
Giardia lamblia	Alpha-tubulin	0.0215	0.3333	0.2944
Leishmania major	epsilon tubulin, putative	0.0207	0.3147	0.2745
Trypanosoma brucei	tubulin gamma chain	0.0207	0.3147	0.2745
Trichomonas vaginalis	tubulin, putative	0.0117	0.1181	0.0633
Loa Loa (eye worm)	tubulin alpha chain	0.0215	0.3333	0.3325
Trichomonas vaginalis	tubulin beta chain, putative	0.0516	0.992	0.9915
Echinococcus multilocularis	Tubulin beta 2C chain	0.0516	0.992	1
Loa Loa (eye worm)	hypothetical protein	0.0215	0.3333	0.3325
Trypanosoma brucei	beta tubulin	0.0207	0.3147	0.2745
Leishmania major	beta tubulin	0.0516	0.992	1
Trichomonas vaginalis	tubulin beta chain, putative	0.0117	0.1181	0.0633
Leishmania major	alpha tubulin	0.0215	0.3333	0.2944
Echinococcus granulosus	tubulin alpha chain	0.0215	0.3333	0.336
Leishmania major	branched-chain amino acid aminotransferase, putative	0.0105	0.0924	0.0363
Echinococcus granulosus	Tubulin beta 2C chain	0.0516	0.992	1
Leishmania major	beta tubulin	0.0516	0.992	1
Trichomonas vaginalis	tubulin alpha-1 chain, putative	0.0098	0.0771	0.0198
Echinococcus multilocularis	Tubulin beta 2C chain	0.0516	0.992	1
Schistosoma mansoni	tubulin subunit beta	0.0516	0.992	1
Trypanosoma brucei	beta tubulin	0.0516	0.992	1
Echinococcus multilocularis	Tubulin beta 2C chain	0.0516	0.992	1
Loa Loa (eye worm)	tubulin beta-1 chain	0.0516	0.992	1
Trypanosoma brucei	epsilon tubulin	0.0207	0.3147	0.2745
Echinococcus multilocularis	tubulin beta 1 chain	0.0516	0.992	1
Trypanosoma brucei	branched-chain amino acid aminotransferase, putative	0.0105	0.0924	0.0363
Echinococcus granulosus	tubulin subunit beta	0.0516	0.992	1
Leishmania major	beta tubulin	0.0516	0.992	1
Toxoplasma gondii	alpha tubulin TUBA1	0.0215	0.3333	0.3325
Toxoplasma gondii	beta-tubulin, putative	0.0516	0.992	1
Trypanosoma brucei	alpha tubulin, putative	0.0117	0.1181	0.0639
Echinococcus multilocularis	peroxisome assembly protein 26	0.0215	0.3333	0.3325
Echinococcus granulosus	tubulin alpha chain	0.0215	0.3333	0.336
Toxoplasma gondii	beta tubulin	0.0516	0.992	1
Brugia malayi	Tubulin alpha-2 chain	0.0215	0.3333	0.3325
Trichomonas vaginalis	tubulin beta chain, putative	0.0215	0.3333	0.2919
Brugia malayi	Branched-chain amino acid aminotransferase, cytosolic, putative	0.0105	0.0924	0.0883
Trichomonas vaginalis	subgroup IIIi aminotransferase, putative	0.0105	0.0924	0.036
Loa Loa (eye worm)	tubulin beta-2A chain	0.0516	0.992	1
Brugia malayi	alpha-tubulin	0.0215	0.3333	0.3325
Schistosoma mansoni	alpha tubulin	0.0215	0.3333	0.3325
Schistosoma mansoni	tubulin subunit delta	0.009	0.0585	0.0539
Trypanosoma brucei	beta tubulin	0.0516	0.992	1
Mycobacterium ulcerans	branched-chain amino acid aminotransferase	0.0105	0.0924	1
Echinococcus granulosus	tubulin beta 4A class IVa	0.0516	0.992	1
Giardia lamblia	Beta tubulin	0.0516	0.992	1
Brugia malayi	Tubulin alpha chain	0.009	0.0585	0.0539
Echinococcus multilocularis	tubulin alpha	0.0207	0.3147	0.3136
Echinococcus multilocularis	tubulin alpha 3 chain	0.0215	0.3333	0.3325
Trypanosoma cruzi	tubulin gamma chain	0.0207	0.3147	0.2745
Trichomonas vaginalis	tubulin gamma chain, putative	0.0207	0.3147	0.2722
Trypanosoma brucei	beta tubulin	0.0516	0.992	1
Trichomonas vaginalis	tubulin alpha chain, putative	0.0117	0.1181	0.0633
Leishmania major	alpha tubulin	0.0215	0.3333	0.2944
Echinococcus multilocularis	tubulin alpha 1C chain	0.0215	0.3333	0.3325
Leishmania major	alpha tubulin	0.0215	0.3333	0.2944
Echinococcus multilocularis	tubulin subunit beta	0.0516	0.992	1
Plasmodium falciparum	alpha tubulin 1	0.0215	0.3333	0.2944
Loa Loa (eye worm)	beta-tubulin	0.0516	0.992	1
Wolbachia endosymbiont of Brugia malayi	cell division protein FtsZ	0.009	0.0585	0.5
Echinococcus granulosus	tubulin alpha 1C chain	0.0215	0.3333	0.336
Toxoplasma gondii	Branched-chain-amino-acid aminotransferase	0.0105	0.0924	0.0883
Schistosoma mansoni	tubulin subunit beta	0.0516	0.992	1
Schistosoma mansoni	tubulin subunit beta	0.0516	0.992	1
Echinococcus granulosus	Tubulin beta 2C chain	0.0516	0.992	1
Echinococcus granulosus	tubulin delta chain	0.009	0.0585	0.0589
Loa Loa (eye worm)	BEN-1 protein	0.0516	0.992	1
Leishmania major	beta tubulin	0.0516	0.992	1
Trypanosoma brucei	alpha tubulin	0.0215	0.3333	0.2944
Loa Loa (eye worm)	tubulin beta chain	0.0516	0.992	1
Schistosoma mansoni	tubulin subunit beta	0.009	0.0585	0.0539
Leishmania major	beta tubulin	0.0516	0.992	1
Trichomonas vaginalis	tubulin beta chain, putative	0.0215	0.3333	0.2919
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0456	0.8618	0.8681
Echinococcus granulosus	Tubulin alpha 1 chain	0.0215	0.3333	0.336
Leishmania major	beta tubulin	0.0516	0.992	1
Echinococcus granulosus	tubulin gamma 1 chain	0.0207	0.3147	0.3173
Trichomonas vaginalis	tubulin alpha chain, putative	0.0117	0.1181	0.0633
Leishmania major	beta tubulin	0.0516	0.992	1
Trichomonas vaginalis	tubulin beta chain, putative	0.0215	0.3333	0.2919
Trypanosoma brucei	alpha tubulin	0.0215	0.3333	0.2944
Schistosoma mansoni	tubulin subunit alpha	0.0215	0.3333	0.3325
Entamoeba histolytica	tubulin family protein	0.0516	0.992	1
Loa Loa (eye worm)	hypothetical protein	0.0098	0.0771	0.0728
Trypanosoma brucei	alpha tubulin	0.0215	0.3333	0.2944
Echinococcus granulosus	alpha tubulin	0.0215	0.3333	0.336
Schistosoma mansoni	alpha tubulin	0.0215	0.3333	0.3325
Echinococcus granulosus	Tubulin beta 2C chain	0.0516	0.992	1
Leishmania major	alpha tubulin	0.0215	0.3333	0.2944
Loa Loa (eye worm)	alpha-tubulin	0.0215	0.3333	0.3325
Plasmodium vivax	tubulin epsilon chain, putative	0.0207	0.3147	0.3136
Leishmania major	beta tubulin	0.0516	0.992	1
Trichomonas vaginalis	tubulin alpha chain, putative	0.0207	0.3147	0.2722
Entamoeba histolytica	tubulin alpha-1 chain	0.0215	0.3333	0.2678
Trichomonas vaginalis	tubulin epsilon chain, putative	0.0215	0.3333	0.2919
Echinococcus multilocularis	tubulin alpha 1C chain	0.0215	0.3333	0.3325
Giardia lamblia	Branched-chain amino acid aminotransferase lateral transfer candidate	0.0105	0.0924	0.0363
Schistosoma mansoni	tubulin subunit alpha	0.0215	0.3333	0.3325
Leishmania major	alpha tubulin	0.0215	0.3333	0.2944
Mycobacterium tuberculosis	Branched-chain amino acid transaminase IlvE	0.0105	0.0924	1
Trichomonas vaginalis	tubulin beta chain, putative	0.0215	0.3333	0.2919
Echinococcus granulosus	tubulin epsilon chain	0.0207	0.3147	0.3173
Echinococcus multilocularis	tubulin alpha 3 chain	0.0215	0.3333	0.3325

Activities

Activity type	Activity value	Assay description	Source	Reference
Ki (binding)	= 0.53 uM	Inhibition of human thrombin using fluorogenic Cbz-Gly-Gly-Arg-NH-Mec as substrate measured over 400 secs by spectrophotometry	ChEMBL.	23026080
Ki (binding)	= 12.5 uM	Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrophotometry	ChEMBL.	23026080

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2159280

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1722928