Detailed information for compound 1722968

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 421.532 | Formula: C25H31N3O3
  • H donors: 1 H acceptors: 3 LogP: 4.1 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc2c(cc1OC)cncc2c1cnc(c(c1)C)N1CCC(CC1)C(O)(C)C
  • InChi: 1S/C25H31N3O3/c1-16-10-17(14-27-24(16)28-8-6-19(7-9-28)25(2,3)29)21-15-26-13-18-11-22(30-4)23(31-5)12-20(18)21/h10-15,19,29H,6-9H2,1-5H3
  • InChiKey: TVVAVPFCJJKHSO-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.007 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0013 0.007 0.0254
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0013 0.007 0.0101
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0013 0.007 0.0101
Echinococcus granulosus segment polarity protein dishevelled 0.001 0.0021 0.003
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0013 0.007 0.0101
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.0013 0.007 0.0254
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Loa Loa (eye worm) RNA binding protein 0.0275 0.4251 0.4251
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0019 0.0173 0.0247
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0013 0.007 0.007
Brugia malayi MH2 domain containing protein 0.0043 0.0557 0.0557
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.0013 0.007 0.0254
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.007 0.0254
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0013 0.007 0.0101
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0013 0.007 0.0101
Echinococcus granulosus mothers against decapentaplegic 2 0.0019 0.0175 0.025
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0013 0.007 0.0101
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0447 0.6994 1
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.001 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0067 0.0942 0.0942
Brugia malayi ubiquitin specific protease 14 0.0013 0.007 0.007
Echinococcus granulosus smad 0.0043 0.0557 0.0796
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.007 0.007
Echinococcus multilocularis smad 0.0043 0.0557 0.0796
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.007 0.0254
Brugia malayi RNA recognition motif domain containing protein 0.0275 0.4251 0.4251
Echinococcus multilocularis segment polarity protein dishevelled 0.001 0.0021 0.003
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0019 0.0173 0.0247
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Schistosoma mansoni Smad4 0.0019 0.0175 0.025
Echinococcus multilocularis segment polarity protein dishevelled 0.001 0.0021 0.003
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0013 0.007 0.0101
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0019 0.0173 0.0247
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0019 0.0173 0.0247
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Echinococcus granulosus mothers against decapentaplegic 6 0.0019 0.0175 0.025
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.007 0.4083
Schistosoma mansoni Smad4 0.0043 0.0557 0.0796
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0013 0.007 0.0101
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0013 0.007 0.0254
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0067 0.0942 0.1347
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0138 0.0497
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 1, putative 0.0013 0.007 0.0254
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0013 0.007 0.0101
Schistosoma mansoni smad1 5 8 and 0.0043 0.0557 0.0796
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.007 0.0254
Schistosoma mansoni tar DNA-binding protein 0.0275 0.4251 0.6079
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0013 0.007 0.0101
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0013 0.007 0.0254
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0013 0.007 0.0101
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.007 0.0254
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0013 0.007 0.0101
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Brugia malayi RNA binding protein 0.0275 0.4251 0.4251
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0013 0.007 0.0101
Brugia malayi TAR-binding protein 0.0275 0.4251 0.4251
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0013 0.007 0.0254
Brugia malayi G-protein alpha subunit 0.0019 0.0173 0.0173
Schistosoma mansoni tar DNA-binding protein 0.0275 0.4251 0.6079
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0138 0.0497
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.001 0.0021 0.003
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0013 0.007 0.0254
Loa Loa (eye worm) hypothetical protein 0.0146 0.219 0.219
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0019 0.0173 0.0247
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Schistosoma mansoni smad1 5 8 and 0.0043 0.0557 0.0796
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.007 0.4083
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0019 0.0173 1
Plasmodium falciparum ubiquitin specific protease, putative 0.0013 0.007 0.0254
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.4083
Loa Loa (eye worm) hypothetical protein 0.0024 0.0248 0.0248
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0013 0.007 0.0254
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.007 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Loa Loa (eye worm) hypothetical protein 0.0013 0.007 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Loa Loa (eye worm) hypothetical protein 0.0013 0.007 0.007
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0013 0.007 0.0101
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.007 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Echinococcus multilocularis regulator of G protein signaling 7 0.001 0.0021 0.003
Trypanosoma brucei PAB1-binding protein , putative 0.0182 0.2771 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0013 0.007 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Plasmodium vivax hypothetical protein, conserved 0.0013 0.007 0.0254
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0019 0.0173 0.0173
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.007 0.0254
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.007 0.007
Giardia lamblia DUB-1 0.0013 0.007 1
Toxoplasma gondii LsmAD domain-containing protein 0.0182 0.2771 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.007 0.4083
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.4083
Brugia malayi MH1 domain containing protein 0.0043 0.0557 0.0557
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0013 0.007 0.0101
Loa Loa (eye worm) hypothetical protein 0.0019 0.0173 0.0173
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.007 0.007
Echinococcus granulosus ubiquitin specific peptidase c family 0.0013 0.007 0.0101
Trichomonas vaginalis ubiquitin specific protease, putative 0.0013 0.007 0.4083
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0019 0.0173 0.0247
Onchocerca volvulus 0.0019 0.0173 0.0506
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0013 0.007 0.0101
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0043 0.0557 0.0796
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0013 0.007 0.0101
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0013 0.007 0.0254
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.007 0.0254
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0213 0.3266 0.3266
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0013 0.007 0.007
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0082 0.1169 0.1672
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0019 0.0173 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.4083
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0013 0.007 0.0101
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Schistosoma mansoni dep domain containing protein 0.001 0.0021 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.4083
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0019 0.0173 0.0173
Brugia malayi MH1 domain containing protein 0.0024 0.0248 0.0248
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.4083
Echinococcus granulosus ubiquitin specific protease 41 0.0013 0.007 0.0101
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0013 0.007 0.0101
Echinococcus granulosus Smad4 0.0043 0.0557 0.0796
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0013 0.007 0.0101
Schistosoma mansoni dishevelled 0.001 0.0021 0.003
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0447 0.6994 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0013 0.007 0.0254
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0013 0.007 0.007
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0067 0.0942 0.1347
Loa Loa (eye worm) hypothetical protein 0.0019 0.0173 0.0173
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0138 0.0138
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0013 0.007 0.0101
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Echinococcus multilocularis mothers against decapentaplegic 2 0.0019 0.0175 0.025
Echinococcus multilocularis tar DNA binding protein 0.0275 0.4251 0.6079
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.007 0.0254
Brugia malayi MH2 domain containing protein 0.0019 0.0175 0.0175
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Brugia malayi hypothetical protein 0.0013 0.007 0.007
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0019 0.0173 1
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Echinococcus multilocularis expressed protein 0.0013 0.007 0.0101
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.4083
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0013 0.007 0.0101
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Brugia malayi MH1 domain containing protein 0.0043 0.0557 0.0557
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Echinococcus granulosus TGF beta signal transducer SmadC 0.0043 0.0557 0.0796
Entamoeba histolytica hypothetical protein 0.0013 0.007 0.4083
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0013 0.007 0.0101
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0019 0.0173 0.0173
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0013 0.007 1
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0013 0.007 0.0101
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0013 0.007 0.0254
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0019 0.0173 0.0173
Loa Loa (eye worm) nuclear factor I 0.0024 0.0248 0.0248
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0019 0.0173 0.0247
Loa Loa (eye worm) hypothetical protein 0.0013 0.007 0.007
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.007 0.007
Brugia malayi hypothetical protein 0.0118 0.1742 0.1742
Schistosoma mansoni smad1 5 8 and 0.0043 0.0557 0.0796
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0013 0.007 0.0101
Brugia malayi MH1 domain containing protein 0.0024 0.0248 0.0248
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Entamoeba histolytica G protein alpha subunit, putative 0.0019 0.0173 1
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0013 0.007 0.0254
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0013 0.007 0.0254
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0019 0.0173 0.0247
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0013 0.007 0.0101
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.007 0.0254
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.001 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0013 0.007 0.007
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0013 0.007 0.0101
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0013 0.007 0.0254
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0019 0.0173 0.0247
Echinococcus multilocularis Smad4 0.0043 0.0557 0.0796
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0013 0.007 0.007
Brugia malayi Smad1 0.0043 0.0557 0.0557
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0043 0.0557 0.0796
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0013 0.007 0.0101
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0013 0.007 0.0254
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0013 0.007 0.0101
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0138 0.0497
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.007 0.4083
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0138 0.5
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0447 0.6994 1
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0013 0.007 0.0254
Onchocerca volvulus 0.0019 0.0173 0.0506
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0138 0.0197
Loa Loa (eye worm) Smad1 0.0043 0.0557 0.0557
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0013 0.007 0.0254
Schistosoma mansoni tar DNA-binding protein 0.0275 0.4251 0.6079
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0138 0.0497
Giardia lamblia Hypothetical protein 0.0013 0.007 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0213 0.3266 0.3266
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Brugia malayi MH2 domain containing protein 0.0043 0.0557 0.0557
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0447 0.6994 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0067 0.0942 0.1347
Loa Loa (eye worm) TAR-binding protein 0.0275 0.4251 0.4251
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Echinococcus multilocularis mothers against decapentaplegic 6 0.0019 0.0175 0.025
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0138 0.0197
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0013 0.007 0.0101
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0019 0.0173 0.0247
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0019 0.0173 0.0247
Plasmodium falciparum ataxin-2 like protein, putative 0.0182 0.2771 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.007 0.4083
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0013 0.007 0.4083
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.4083
Loa Loa (eye worm) MH2 domain-containing protein 0.0019 0.0175 0.0175
Echinococcus multilocularis ubiquitin specific protease 41 0.0013 0.007 0.0101
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0013 0.007 0.0101
Toxoplasma gondii hypothetical protein 0.001 0.0021 0.0077
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0019 0.0173 0.0247
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0447 0.6994 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0013 0.007 0.0101
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0013 0.007 0.0101
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0013 0.007 0.0101
Plasmodium vivax ubiquitin specific protease, putative 0.0013 0.007 0.0254
Loa Loa (eye worm) hypothetical protein 0.0013 0.007 0.007
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0197 0.3011 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Loa Loa (eye worm) hypothetical protein 0.0013 0.007 0.007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0013 0.007 0.4083
Loa Loa (eye worm) hypothetical protein 0.0182 0.2771 0.2771
Brugia malayi isocitrate dehydrogenase 0.0017 0.0138 0.0138
Echinococcus multilocularis expressed protein 0.0019 0.0173 0.0247
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0013 0.007 0.0101
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.007 0.0254
Schistosoma mansoni GTP-binding protein alpha subunit 0.0019 0.0173 0.0247
Echinococcus granulosus Pleckstrin G protein interacting region 0.001 0.0021 0.003
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0013 0.007 0.0254
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0013 0.007 0.0254
Schistosoma mansoni smad 0.0043 0.0557 0.0796
Loa Loa (eye worm) hypothetical protein 0.0019 0.0173 0.0173
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Brugia malayi Calcitonin receptor-like protein seb-1 0.0213 0.3266 0.3266
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0013 0.007 0.0254
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0013 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0013 0.007 0.007
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0019 0.0173 1
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0013 0.007 0.4083
Schistosoma mansoni tar DNA-binding protein 0.0275 0.4251 0.6079
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Brugia malayi hypothetical protein 0.0019 0.0173 0.0173
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0013 0.007 0.0254
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0013 0.007 0.0101
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0013 0.007 0.0101
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.001 0.0021 0.003
Schistosoma mansoni Smad4 0.0019 0.0175 0.025
Echinococcus granulosus regulator of G protein signaling 7 0.001 0.0021 0.003
Trichomonas vaginalis ubiquitin specific protease, putative 0.0013 0.007 0.4083
Plasmodium falciparum ataxin-2 like protein, putative 0.0182 0.2771 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0013 0.007 0.0101
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0013 0.007 0.0101
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.001 0.0021 0.0021
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0013 0.007 0.0101
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0067 0.0942 0.1347
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.4083
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0019 0.0173 0.0173
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.4083
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0019 0.0173 0.0173
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0019 0.0175 0.0514
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0013 0.007 0.0101
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0013 0.007 0.007
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.0013 0.007 0.0254
Schistosoma mansoni hypothetical protein 0.0067 0.0942 0.1347
Plasmodium falciparum ubiquitin specific protease, putative 0.0013 0.007 0.0254
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0013 0.007 0.0101
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.007 0.4083
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0013 0.007 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0019 0.0173 0.0173
Loa Loa (eye worm) MH2 domain-containing protein 0.0043 0.0557 0.0557
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Schistosoma mansoni hypothetical protein 0.0082 0.1169 0.1672
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0013 0.007 0.007
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0082 0.1169 0.1672
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0013 0.007 0.007
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0013 0.007 0.0101
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.007 0.4083
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.4083
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.007 0.4083
Loa Loa (eye worm) hypothetical protein 0.0019 0.0173 0.0173
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0447 0.6994 1
Schistosoma mansoni calpain-7 (C02 family) 0.0013 0.007 0.0101
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0019 0.0173 0.0247
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0019 0.0173 0.0173
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0019 0.0173 0.0173
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0013 0.007 0.0254
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0447 0.6994 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0138 0.0197
Brugia malayi latrophilin 2 splice variant baaae 0.0146 0.219 0.219
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Echinococcus granulosus regulator of G protein signaling 7 0.001 0.0021 0.003
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.4083
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0019 0.0173 0.0173
Echinococcus granulosus GPCR family 2 0.0067 0.0942 0.1347
Loa Loa (eye worm) hypothetical protein 0.0013 0.007 0.007
Schistosoma mansoni regulator of G protein signaling 0.001 0.0021 0.003
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0013 0.007 0.0101
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.007 0.4083
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0013 0.007 0.0101
Echinococcus multilocularis regulator of G protein signaling 7 0.001 0.0021 0.003
Onchocerca volvulus 0.0013 0.007 0.0165
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.007 0.007
Schistosoma mansoni hypothetical protein 0.0067 0.0942 0.1347
Schistosoma mansoni GTP-binding protein alpha subunit 0.0019 0.0173 0.0247
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.007 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Loa Loa (eye worm) hypothetical protein 0.0213 0.3266 0.3266
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.007 0.007
Schistosoma mansoni calpain-7 (C02 family) 0.0013 0.007 0.0101
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0067 0.0942 0.0942
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0019 0.0173 0.0173
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0013 0.007 0.0101
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0013 0.007 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.4083
Leishmania major hypothetical protein, conserved 0.0182 0.2771 1
Trichomonas vaginalis ubiquitin specific protease, putative 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Brugia malayi DIX domain containing protein 0.001 0.0021 0.0021
Brugia malayi hypothetical protein 0.001 0.0021 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.4083
Brugia malayi mothers against decapentaplegic homolog 3 0.0019 0.0175 0.0175
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0013 0.007 0.007
Schistosoma mansoni hypothetical protein 0.0013 0.007 0.0101
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0013 0.007 0.0254
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0019 0.0173 0.0247
Loa Loa (eye worm) latrophilin receptor protein 2 0.0067 0.0942 0.0942
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Echinococcus granulosus expressed protein 0.0019 0.0173 0.0247
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0019 0.0173 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.4083
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0013 0.007 0.0101
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Schistosoma mansoni dishevelled 0.001 0.0021 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.4083
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.007 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 2, putative 0.0013 0.007 0.0254
Loa Loa (eye worm) MH1 domain-containing protein 0.0019 0.0175 0.0175
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.007 0.0254
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0019 0.0173 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0013 0.007 0.0101
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.007 0.007
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0013 0.007 0.0101
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0013 0.007 0.0101
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0138 0.0497
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.4083
Schistosoma mansoni z-protein (S1r protein) 0.001 0.0021 0.003
Brugia malayi Latrophilin receptor protein 2 0.0067 0.0942 0.0942
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0021
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.007 0.007
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0013 0.007 0.0254
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0013 0.007 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0447 0.6994 0.6994
Schistosoma mansoni hypothetical protein 0.0067 0.0942 0.1347
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0013 0.007 0.0254
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0275 0.4251 0.4251
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0013 0.007 0.0101
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0013 0.007 0.0101
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0013 0.007 0.0101
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0013 0.007 0.0101
Schistosoma mansoni hypothetical protein 0.0067 0.0942 0.1347
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0013 0.007 0.0254
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.007 0.4083
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0019 0.0173 0.0173
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.007 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0013 0.007 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.4083
Loa Loa (eye worm) hypothetical protein 0.001 0.0021 0.0021
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.007 0.007
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0138 0.0197
Schistosoma mansoni smad 0.0019 0.0175 0.025
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0138 0.0197
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.007 0.4083
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0013 0.007 0.0254
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0138 0.0497
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0138 0.0497
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase family 2, putative 0.0013 0.007 0.0254
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0013 0.007 0.0101
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0013 0.007 0.007
Plasmodium vivax ataxin-2 like protein, putative 0.0182 0.2771 1
Schistosoma mansoni hypothetical protein 0.0146 0.219 0.3132
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Loa Loa (eye worm) G protein alpha subunit 3 0.0019 0.0173 0.0173
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.007 0.0254
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0013 0.007 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0013 0.007 0.0254
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.007 0.4083
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0019 0.0173 0.0173
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.007 0.4083
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0447 0.6994 0.6994
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0013 0.007 0.0101
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0013 0.007 0.007
Onchocerca volvulus 0.0013 0.007 0.0165
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.007 0.0254
Echinococcus multilocularis GPCR, family 2 0.0067 0.0942 0.1347
Toxoplasma gondii hypothetical protein 0.0013 0.007 0.0254
Trypanosoma cruzi PAB1-binding protein , putative 0.0182 0.2771 1
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0013 0.007 0.0101
Echinococcus multilocularis mothers against decapentaplegic 5 0.0043 0.0557 0.0796
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0013 0.007 0.0101
Loa Loa (eye worm) hypothetical protein 0.0013 0.007 0.007
Brugia malayi hypothetical protein 0.0182 0.2771 0.2771
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0019 0.0173 0.0247
Trypanosoma cruzi PAB1-binding protein , putative 0.0182 0.2771 1
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0019 0.0173 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Loa Loa (eye worm) hypothetical protein 0.0197 0.3011 0.3011
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.4083
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0019 0.0173 0.0247
Brugia malayi regulator of G-protein signaling egl-10 0.001 0.0021 0.0021
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0019 0.0173 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0013 0.007 0.0101
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0138 0.0197
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0138 0.0497
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Loa Loa (eye worm) MH1 domain-containing protein 0.0043 0.0557 0.0557
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0138 0.0197
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.007 0.0254
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0019 0.0173 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0013 0.007 0.0254
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Brugia malayi N-terminal motif family protein 0.0197 0.3011 0.3011
Brugia malayi hypothetical protein 0.001 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0013 0.007 0.0254
Toxoplasma gondii ubiquitin-specific protease USP4 0.0013 0.007 0.0254
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0019 0.0173 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Echinococcus granulosus segment polarity protein dishevelled 0.001 0.0021 0.003
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0013 0.007 0.0254
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0013 0.007 0.0254
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0013 0.007 0.0101
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0013 0.007 0.0254
Loa Loa (eye worm) hypothetical protein 0.0019 0.0175 0.0175
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0019 0.0173 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.4083
Onchocerca volvulus 0.0019 0.0173 0.0506
Loa Loa (eye worm) hypothetical protein 0.0013 0.007 0.007
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0013 0.007 0.0254
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.007 0.4083
Loa Loa (eye worm) DIX domain-containing protein 0.001 0.0021 0.0021
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.007 0.0254
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Schistosoma mansoni tar DNA-binding protein 0.0275 0.4251 0.6079
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0013 0.007 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0173 0.0173
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0013 0.007 0.0254
Onchocerca volvulus 0.0013 0.007 0.0165
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0013 0.007 0.4083
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.007 0.4083
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0013 0.007 0.0254
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0019 0.0173 0.0247
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0019 0.0173 0.0247
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0013 0.007 0.0254
Echinococcus granulosus tar DNA binding protein 0.0275 0.4251 0.6079
Loa Loa (eye worm) hypothetical protein 0.0013 0.007 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0013 0.007 0.0254
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.007 0.4083
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.007 0.4083
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0013 0.007 0.0254
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0138 0.0497
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0013 0.007 0.0101
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0013 0.007 0.4083
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0013 0.007 0.0254
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0013 0.007 0.007
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0013 0.007 0.0101
Echinococcus granulosus mothers against decapentaplegic 5 0.0043 0.0557 0.0796
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0013 0.007 0.4083
Schistosoma mansoni peptidase 0.0013 0.007 0.0101

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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