Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0064 | 0.0443 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0443 | 0.1076 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Schistosoma mansoni | polycystin 1-related | 0.0064 | 0.0443 | 0.0443 |
Schistosoma mansoni | rab6-interacting | 0.0064 | 0.0443 | 0.0443 |
Brugia malayi | EGF-like domain containing protein | 0.006 | 0.0332 | 0.0806 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.0332 | 0.0332 |
Echinococcus granulosus | protein jagged 2 | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | EGF-like domain containing protein | 0.006 | 0.0332 | 0.0806 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Brugia malayi | EGF-like domain containing protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0064 | 0.0443 | 0.0443 |
Schistosoma mansoni | notch | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0187 | 0.4118 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Onchocerca volvulus | 0.0187 | 0.4118 | 1 | |
Echinococcus granulosus | notch | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Onchocerca volvulus | Peroxidase homolog | 0.0187 | 0.4118 | 1 |
Onchocerca volvulus | 0.0064 | 0.0443 | 0.0294 | |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Brugia malayi | GCC2 and GCC3 family protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus multilocularis | protein jagged 1 | 0.006 | 0.0332 | 0.0332 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0064 | 0.0443 | 0.0443 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.006 | 0.0332 | 0.0332 |
Echinococcus granulosus | protein jagged 1 | 0.006 | 0.0332 | 0.0332 |
Schistosoma mansoni | notch | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Brugia malayi | Muscle positioning protein 4 | 0.006 | 0.0332 | 0.0806 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Echinococcus granulosus | protein jagged 1 | 0.006 | 0.0332 | 0.0332 |
Onchocerca volvulus | Dual oxidase homolog | 0.0187 | 0.4118 | 1 |
Schistosoma mansoni | peroxidasin | 0.0187 | 0.4118 | 0.4118 |
Giardia lamblia | High cysteine protein | 0.006 | 0.0332 | 1 |
Brugia malayi | EGF-like domain containing protein | 0.006 | 0.0332 | 0.0806 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0187 | 0.4118 | 1 |
Schistosoma mansoni | notch | 0.006 | 0.0332 | 0.0332 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0064 | 0.0443 | 0.0443 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | Animal haem peroxidase family protein | 0.0187 | 0.4118 | 1 |
Onchocerca volvulus | 0.0064 | 0.0443 | 0.0294 | |
Echinococcus multilocularis | neurogenic locus protein delta | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Schistosoma mansoni | septate junction protein | 0.006 | 0.0332 | 0.0332 |
Echinococcus multilocularis | notch | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | Animal haem peroxidase family protein | 0.0187 | 0.4118 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Echinococcus multilocularis | peroxidasin | 0.0187 | 0.4118 | 0.4118 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0065 | 0.0479 | 0.1162 |
Schistosoma mansoni | peroxidasin | 0.0187 | 0.4118 | 0.4118 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0065 | 0.0479 | 0.0479 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0065 | 0.0479 | 0.0479 |
Onchocerca volvulus | Peroxidase homolog | 0.0187 | 0.4118 | 1 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0187 | 0.4118 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0166 | 0.3487 | 0.3487 |
Schistosoma mansoni | notch | 0.006 | 0.0332 | 0.0332 |
Schistosoma mansoni | Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0064 | 0.0443 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.0332 | 0.0332 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0065 | 0.0479 | 0.0479 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus multilocularis | protein jagged 2 | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | hypothetical protein | 0.0064 | 0.0443 | 0.1076 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0443 | 0.0443 |
Schistosoma mansoni | jumonji domain containing protein | 0.0065 | 0.0479 | 0.0479 |
Schistosoma mansoni | rab6-interacting | 0.0064 | 0.0443 | 0.0443 |
Brugia malayi | jmjC domain containing protein | 0.0065 | 0.0479 | 0.1162 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | Animal haem peroxidase family protein | 0.0187 | 0.4118 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0187 | 0.4118 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0187 | 0.4118 | 1 |
Brugia malayi | hypothetical protein | 0.0064 | 0.0443 | 0.1076 |
Schistosoma mansoni | notch | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | Blistered cuticle protein 3 | 0.0187 | 0.4118 | 1 |
Echinococcus multilocularis | neural cadherin | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus granulosus | neurogenic locus protein delta | 0.006 | 0.0332 | 0.0332 |
Echinococcus granulosus | delta-like protein 1 | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.006 | 0.0332 | 0.0806 |
Brugia malayi | jmjC domain containing protein | 0.0065 | 0.0479 | 0.1162 |
Echinococcus granulosus | neurogenic locus notch protein 4 | 0.006 | 0.0332 | 0.0332 |
Echinococcus granulosus | muscleblind protein | 0.0166 | 0.3487 | 0.3487 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus multilocularis | slit 2 protein | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | notch protein | 0.006 | 0.0332 | 0.0806 |
Onchocerca volvulus | 0.0187 | 0.4118 | 1 | |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0065 | 0.0479 | 0.0479 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Brugia malayi | Cadherin domain containing protein | 0.006 | 0.0332 | 0.0806 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | notch-like transmembrane receptor | 0.006 | 0.0332 | 0.0806 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus granulosus | fibropellin Ia | 0.006 | 0.0332 | 0.0332 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.006 | 0.0332 | 0.0806 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus multilocularis | fibropellin Ia | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | Cadherin domain containing protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus multilocularis | protein jagged 1 | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0187 | 0.4118 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0443 | 0.1076 |
Schistosoma mansoni | cell polarity protein | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0064 | 0.0443 | 0.0443 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0187 | 0.4118 | 1 |
Loa Loa (eye worm) | Notch2 | 0.006 | 0.0332 | 0.0806 |
Echinococcus granulosus | neural cadherin | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | Muscleblind-like protein | 0.0166 | 0.3487 | 0.8468 |
Schistosoma mansoni | lipoxygenase | 0.0268 | 0.6547 | 0.6547 |
Brugia malayi | Transmembrane cell adhesion receptor mua-3 precursor, putative | 0.006 | 0.0332 | 0.0806 |
Schistosoma mansoni | loxhd1 | 0.0064 | 0.0443 | 0.0443 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | Animal haem peroxidase family protein | 0.0187 | 0.4118 | 1 |
Echinococcus granulosus | RUN | 0.0064 | 0.0443 | 0.0443 |
Echinococcus granulosus | protein jagged 2 | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | Doublecortin family protein | 0.0064 | 0.0443 | 0.1076 |
Echinococcus multilocularis | fat cadherin tumor suppressor | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.3487 | 0.8468 |
Echinococcus multilocularis | muscleblind protein | 0.0166 | 0.3487 | 0.3487 |
Brugia malayi | EGF-like domain containing protein | 0.006 | 0.0332 | 0.0806 |
Brugia malayi | Delta serrate ligand family protein | 0.006 | 0.0332 | 0.0806 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus multilocularis | RUN | 0.0064 | 0.0443 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.3487 | 0.8468 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0064 | 0.0443 | 0.0443 |
Brugia malayi | EGF-like domain containing protein | 0.006 | 0.0332 | 0.0806 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus granulosus | peroxidasin | 0.0187 | 0.4118 | 0.4118 |
Brugia malayi | hypothetical protein | 0.0187 | 0.4118 | 1 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.0332 | 0.0332 |
Echinococcus granulosus | slit 2 protein | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | Animal haem peroxidase family protein | 0.0187 | 0.4118 | 1 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0065 | 0.0479 | 0.0479 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0187 | 0.4118 | 1 |
Schistosoma mansoni | slit | 0.006 | 0.0332 | 0.0332 |
Schistosoma mansoni | laminin gamma-3 chain | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus multilocularis | neurogenic locus notch protein 4 | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | Peroxidasin | 0.0187 | 0.4118 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Onchocerca volvulus | 0.0187 | 0.4118 | 1 | |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0065 | 0.0479 | 0.0479 |
Loa Loa (eye worm) | doublecortin family protein | 0.0064 | 0.0443 | 0.1076 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0064 | 0.0443 | 0.0443 |
Echinococcus granulosus | neurogenic locus notch protein | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0332 | 0.0806 |
Echinococcus granulosus | neurogenic locus notch protein | 0.006 | 0.0332 | 0.0332 |
Brugia malayi | EGF-like domain containing protein | 0.006 | 0.0332 | 0.0806 |
Toxoplasma gondii | EGF family domain-containing protein | 0.006 | 0.0332 | 1 |
Schistosoma mansoni | notch | 0.006 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.4118 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.