Detailed information for compound 1723841

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 375.394 | Formula: C19H22FN3O4
  • H donors: 1 H acceptors: 2 LogP: 2.69 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: FCCOCCOCCOc1ccc2c(c1)nc(o2)c1ccc(nc1)NC
  • InChi: 1S/C19H22FN3O4/c1-21-18-5-2-14(13-22-18)19-23-16-12-15(3-4-17(16)27-19)26-11-10-25-9-8-24-7-6-20/h2-5,12-13H,6-11H2,1H3,(H,21,22)
  • InChiKey: XZOFXENTMWJTRV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.012 0.012
Loa Loa (eye worm) MH2 domain-containing protein 0.0028 0.0091 0.0091
Schistosoma mansoni smad 0.0028 0.0091 0.0091
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0051 0.0343 0.0343
Brugia malayi MH1 domain containing protein 0.0035 0.0164 0.0164
Loa Loa (eye worm) nuclear factor I 0.0035 0.0164 0.0164
Loa Loa (eye worm) TAR-binding protein 0.0271 0.2753 0.2753
Loa Loa (eye worm) hypothetical protein 0.0299 0.306 0.306
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.012 0.012
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.012 0.012
Brugia malayi hypothetical protein 0.0072 0.0574 0.0574
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.0467 0.0431
Loa Loa (eye worm) hypothetical protein 0.0031 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0247 0.2482 0.2482
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.012 0.012
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0105 0.0937 0.0937
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0271 0.2753 0.2753
Trichomonas vaginalis glutaminase, putative 0.0551 0.5809 0.5036
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0051 0.0343 0.0343
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0023 0.0037 0.0037
Echinococcus multilocularis ornithine aminotransferase 0.0023 0.0037 0.0037
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.0574 0.0574
Brugia malayi latrophilin 2 splice variant baaae 0.0228 0.2275 0.2275
Schistosoma mansoni thyroid hormone receptor 0.016 0.1532 0.1532
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0053 0.0363 0.0363
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.012 0.012
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.012 0.012
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0366 0.3788 0.3788
Echinococcus multilocularis microtubule associated protein 2 0.0707 0.7522 0.7522
Brugia malayi RNA binding protein 0.0271 0.2753 0.2753
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0051 0.0343 0.0308
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.012 0.012
Brugia malayi glutaminase DH11.1 0.0551 0.5809 0.5809
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.012 0.012
Schistosoma mansoni Smad4 0.0028 0.0091 0.0091
Schistosoma mansoni hypothetical protein 0.0174 0.1688 0.1688
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.0467 0.0467
Echinococcus granulosus smad 0.0063 0.047 0.047
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.012 0.012
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.007 0.0545 0.0545
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.0467 0.0431
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.012 0.1453
Loa Loa (eye worm) MH2 domain-containing protein 0.0063 0.047 0.047
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.012 0.012
Loa Loa (eye worm) MH1 domain-containing protein 0.0063 0.047 0.047
Echinococcus multilocularis geminin 0.0174 0.1688 0.1688
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.012 0.012
Schistosoma mansoni hypothetical protein 0.0129 0.1196 0.1196
Echinococcus multilocularis GPCR, family 2 0.0105 0.0937 0.0937
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0085 0.0712 0.0712
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.012 0.012
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0066 0.0508 0.0508
Plasmodium falciparum ataxin-2 like protein, putative 0.0247 0.2482 0.2455
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.012 0.012
Echinococcus multilocularis calpain A 0.007 0.0545 0.0545
Echinococcus granulosus TGF beta signal transducer SmadC 0.0063 0.047 0.047
Brugia malayi TAR-binding protein 0.0271 0.2753 0.2753
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.012 0.012
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0051 0.0343 0.0343
Loa Loa (eye worm) calpain family protein 1 0.0046 0.0293 0.0293
Echinococcus multilocularis tar DNA binding protein 0.0271 0.2753 0.2753
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.012 0.012
Echinococcus multilocularis mothers against decapentaplegic 6 0.0028 0.0091 0.0091
Schistosoma mansoni metabotropic glutamate receptor 0.0036 0.0178 0.0178
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0063 0.047 0.047
Onchocerca volvulus 0.0031 0.012 0.1453
Trypanosoma cruzi PAB1-binding protein , putative 0.0247 0.2482 0.2482
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0162 0.1558 0.1527
Schistosoma mansoni glutaminase 0.0551 0.5809 0.5809
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.012 0.012
Echinococcus granulosus GPCR family 2 0.0105 0.0937 0.0937
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.012 0.012
Schistosoma mansoni hypothetical protein 0.0174 0.1688 0.1688
Loa Loa (eye worm) transcription factor SMAD2 0.0919 0.9839 0.9839
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.012 0.012
Schistosoma mansoni hypothetical protein 0.0105 0.0937 0.0937
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.0574 0.0574
Brugia malayi Calcitonin receptor-like protein seb-1 0.0333 0.3428 0.3428
Brugia malayi calpain family protein 1 0.0066 0.0508 0.0508
Loa Loa (eye worm) glutaminase 0.0551 0.5809 0.5809
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.012 0.012
Brugia malayi Smad1 0.0063 0.047 0.047
Brugia malayi hypothetical protein 0.0159 0.1526 0.1526
Loa Loa (eye worm) RNA binding protein 0.0271 0.2753 0.2753
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0333 0.3428 0.3428
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.012 0.012
Loa Loa (eye worm) MH1 domain-containing protein 0.0028 0.0091 0.0091
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0467 0.0431
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.012 0.012
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.012 0.012
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.012 0.012
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0467 0.0431
Echinococcus granulosus metabotropic glutamate receptor 5 0.0053 0.0363 0.0363
Echinococcus multilocularis kelch ECH associated protein 1 0.0092 0.0796 0.0796
Schistosoma mansoni adenosylhomocysteinase 0.0578 0.6106 0.6106
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.012 0.1453
Echinococcus multilocularis calpain family protein 1, d 0.0046 0.0293 0.0293
Schistosoma mansoni smad1 5 8 and 0.0063 0.047 0.047
Echinococcus multilocularis Aminotransferase class III 0.0023 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0035 0.0164 0.0164
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.012 0.012
Schistosoma mansoni tar DNA-binding protein 0.0271 0.2753 0.2753
Echinococcus multilocularis thyroid hormone receptor alpha 0.016 0.1532 0.1532
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0085 0.0712 0.0712
Schistosoma mansoni hypothetical protein 0.0111 0.0995 0.0995
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.012 0.012
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.012 0.012
Echinococcus granulosus mothers against decapentaplegic 2 0.0028 0.0091 0.0091
Echinococcus granulosus mothers against decapentaplegic 6 0.0028 0.0091 0.0091
Schistosoma mansoni adenosylhomocysteinase 0.0578 0.6106 0.6106
Trypanosoma cruzi PAB1-binding protein , putative 0.0247 0.2482 0.2482
Brugia malayi metabotropic glutamate receptor type 2 0.0021 0.0014 0.0014
Loa Loa (eye worm) latrophilin receptor protein 2 0.0105 0.0937 0.0937
Echinococcus multilocularis mothers against decapentaplegic 5 0.0063 0.047 0.047
Schistosoma mansoni hypothetical protein 0.0228 0.2275 0.2275
Toxoplasma gondii isocitrate dehydrogenase 0.0051 0.0343 0.0308
Brugia malayi hypothetical protein 0.0247 0.2482 0.2482
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.012 0.012
Entamoeba histolytica hypothetical protein 0.0072 0.0574 0.0574
Loa Loa (eye worm) Smad1 0.0063 0.047 0.047
Entamoeba histolytica hypothetical protein 0.0072 0.0574 0.0574
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.012 0.012
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0063 0.047 0.047
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.012 0.012
Echinococcus granulosus calpain A 0.007 0.0545 0.0545
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0105 0.0937 0.0937
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0023 0.0037 0.5
Echinococcus multilocularis kelch ECH associated protein 1 0.0092 0.0796 0.0796
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.007 0.0545 0.0545
Echinococcus multilocularis Kelch repeat type 1 0.0093 0.0799 0.0799
Plasmodium vivax ornithine aminotransferase, putative 0.0023 0.0037 0.0037
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0051 0.0343 0.0343
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0467 0.0467
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0333 0.3428 0.3428
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0051 0.0343 0.0343
Schistosoma mansoni nuclear hormone receptor 0.0031 0.012 0.012
Echinococcus multilocularis muscleblind protein 0.0299 0.306 0.306
Schistosoma mansoni adenosylhomocysteinase 0.0578 0.6106 0.6106
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0051 0.0343 0.0343
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.012 0.012
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0111 0.0995 0.0995
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0036 0.0178 0.0178
Loa Loa (eye worm) glutaminase 2 0.0551 0.5809 0.5809
Plasmodium vivax ataxin-2 like protein, putative 0.0247 0.2482 0.2482
Brugia malayi nuclear hormone receptor 0.0031 0.012 0.012
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0129 0.1196 0.1196
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.012 0.012
Echinococcus granulosus microtubule associated protein 2 0.0707 0.7522 0.7522
Brugia malayi MH1 domain containing protein 0.0035 0.0164 0.0164
Schistosoma mansoni Smad4 0.0063 0.047 0.047
Echinococcus granulosus metabotropic glutamate receptor 2 0.0036 0.0178 0.0178
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0049 0.0319 0.0319
Schistosoma mansoni metabotropic glutamate receptor 0.0021 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0046 0.0293 0.0293
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0051 0.0343 0.0343
Echinococcus granulosus kelch ECH associated protein 1 0.0092 0.0796 0.0796
Loa Loa (eye worm) MH2 domain-containing protein 0.0919 0.9839 0.9839
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0051 0.0343 0.0343
Brugia malayi MH2 domain containing protein 0.0063 0.047 0.047
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0051 0.0343 0.0308
Schistosoma mansoni thyroid hormone receptor 0.016 0.1532 0.1532
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0051 0.0343 0.0343
Schistosoma mansoni hypothetical protein 0.0072 0.0574 0.0574
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.012 0.012
Schistosoma mansoni coup transcription factor 0.0031 0.012 0.012
Echinococcus granulosus tar DNA binding protein 0.0271 0.2753 0.2753
Echinococcus granulosus Smad4 0.0063 0.047 0.047
Schistosoma mansoni tar DNA-binding protein 0.0271 0.2753 0.2753
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0023 0.0037 0.0037
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0105 0.0937 0.0937
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0105 0.0937 0.0937
Brugia malayi MH2 domain containing protein 0.0028 0.0091 0.0091
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0162 0.1558 0.1527
Loa Loa (eye worm) hypothetical protein 0.0105 0.0937 0.0937
Schistosoma mansoni calpain-7 (C02 family) 0.0023 0.0033 0.0033
Echinococcus granulosus mothers against decapentaplegic 5 0.0063 0.047 0.047
Echinococcus multilocularis smad 0.0063 0.047 0.047
Brugia malayi calpain family protein 1 0.0066 0.0508 0.0508
Brugia malayi Muscleblind-like protein 0.0299 0.306 0.306
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.012 0.012
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.007 0.0545 0.0545
Echinococcus multilocularis isocitrate dehydrogenase 0.0051 0.0343 0.0343
Echinococcus multilocularis Smad4 0.0063 0.047 0.047
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0129 0.1196 0.1196
Mycobacterium tuberculosis Probable aminotransferase 0.0162 0.1558 0.1527
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0028 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0031 0.012 0.012
Brugia malayi Metabotropic glutamate receptor precursor. 0.0043 0.0255 0.0255
Loa Loa (eye worm) hypothetical protein 0.0299 0.306 0.306
Loa Loa (eye worm) hypothetical protein 0.0046 0.0293 0.0293
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.007 0.0545 0.0545
Brugia malayi RNA recognition motif domain containing protein 0.0271 0.2753 0.2753
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0051 0.0343 0.0343
Brugia malayi MH2 domain containing protein 0.0063 0.047 0.047
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.0574 0.0574
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0039 0.0211 0.0211
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.012 0.012
Schistosoma mansoni smad1 5 8 and 0.0063 0.047 0.047
Loa Loa (eye worm) hypothetical protein 0.0031 0.012 0.012
Brugia malayi MH2 domain containing protein 0.0919 0.9839 0.9839
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.012 0.1453
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0066 0.0508 0.0508
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.012 0.012
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0366 0.3788 0.3788
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0293 0.2991 0.1698
Brugia malayi MH1 domain containing protein 0.0063 0.047 0.047
Loa Loa (eye worm) calpain family protein 1 0.0066 0.0508 0.0508
Entamoeba histolytica hypothetical protein 0.0072 0.0574 0.0574
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0366 0.3788 0.3788
Loa Loa (eye worm) hypothetical protein 0.0031 0.012 0.012
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.012 0.012
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.012 0.012
Echinococcus granulosus ornithine aminotransferase 0.0023 0.0037 0.0037
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.012 0.012
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0467 0.0467
Schistosoma mansoni smad1 5 8 and 0.0063 0.047 0.047
Mycobacterium ulcerans glutaminase 0.0551 0.5809 0.5793
Onchocerca volvulus 0.0046 0.0293 1
Loa Loa (eye worm) hypothetical protein 0.0085 0.0712 0.0712
Brugia malayi Isocitrate dehydrogenase 0.0051 0.0343 0.0343
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.012 0.012
Schistosoma mansoni hypothetical protein 0.0093 0.0799 0.0799
Schistosoma mansoni calpain-7 (C02 family) 0.0023 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0228 0.2275 0.2275
Echinococcus multilocularis mothers against decapentaplegic 2 0.0028 0.0091 0.0091
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0333 0.3428 0.3428
Schistosoma mansoni microtubule-associated protein tau 0.0707 0.7522 0.7522
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.012 0.012
Brugia malayi isocitrate dehydrogenase 0.0051 0.0343 0.0343
Echinococcus multilocularis ornithine aminotransferase 0.0023 0.0037 0.0037
Plasmodium falciparum ataxin-2 like protein, putative 0.0247 0.2482 0.2455
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.0467 0.0467
Loa Loa (eye worm) hypothetical protein 0.0031 0.012 0.012
Schistosoma mansoni hypothetical protein 0.0105 0.0937 0.0937
Loa Loa (eye worm) hypothetical protein 0.0053 0.0363 0.0363
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.012 0.012
Echinococcus granulosus geminin 0.0174 0.1688 0.1688
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0111 0.0995 0.0995
Schistosoma mansoni adenosylhomocysteinase 0.0578 0.6106 0.6106
Loa Loa (eye worm) glutamate receptor 0.0043 0.0255 0.0255
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0051 0.0343 0.0343
Brugia malayi mothers against decapentaplegic homolog 3 0.0028 0.0091 0.0091
Echinococcus granulosus muscleblind protein 0.0299 0.306 0.306
Echinococcus granulosus FTZ F1 alpha 0.0031 0.012 0.012
Trypanosoma brucei PAB1-binding protein , putative 0.0247 0.2482 0.2482
Brugia malayi ecdysteroid receptor 0.0031 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0031 0.012 0.012
Leishmania major hypothetical protein, conserved 0.0247 0.2482 0.2482
Loa Loa (eye worm) hypothetical protein 0.0066 0.0508 0.0508
Brugia malayi MH1 domain containing protein 0.0063 0.047 0.047
Echinococcus multilocularis muscleblind protein 1 0.0299 0.306 0.306
Toxoplasma gondii LsmAD domain-containing protein 0.0247 0.2482 0.2455
Echinococcus granulosus Aminotransferase class III 0.0023 0.0037 0.0037
Brugia malayi nuclear receptor NHR-88 0.0031 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0031 0.012 0.012
Schistosoma mansoni hypothetical protein 0.0105 0.0937 0.0937
Schistosoma mansoni tar DNA-binding protein 0.0271 0.2753 0.2753
Mycobacterium ulcerans hypothetical protein 0.0162 0.1558 0.1527
Echinococcus granulosus kelch ECH associated protein 1 like 0.0092 0.0796 0.0796
Schistosoma mansoni Smad4 0.0028 0.0091 0.0091
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.012 0.012
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0105 0.0937 0.0937
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.012 0.012
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0837 0.8941 0.8941
Schistosoma mansoni smad 0.0063 0.047 0.047
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.012 0.012
Schistosoma mansoni tar DNA-binding protein 0.0271 0.2753 0.2753
Schistosoma mansoni tar DNA-binding protein 0.0271 0.2753 0.2753
Brugia malayi steroid hormone receptor 0.0031 0.012 0.012
Echinococcus granulosus kelch ECH associated protein 1 like 0.0092 0.0796 0.0796
Schistosoma mansoni hypothetical protein 0.0105 0.0937 0.0937
Entamoeba histolytica hypothetical protein 0.0072 0.0574 0.0574
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0467 0.0431
Loa Loa (eye worm) hypothetical protein 0.0031 0.012 0.012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.012 0.012
Toxoplasma gondii isocitrate dehydrogenase 0.0051 0.0343 0.0308
Brugia malayi Latrophilin receptor protein 2 0.0105 0.0937 0.0937
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.0467 0.0467
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.012 0.012
Loa Loa (eye worm) isocitrate dehydrogenase 0.0051 0.0343 0.0343
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0023 0.0037 0.5
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0051 0.0343 0.0343
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0162 0.1558 0.1527

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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