Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0365 | 0.0855 |
Echinococcus granulosus | tumor protein p63 | 0.0396 | 0.4703 | 0.4675 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.007 | 0.0164 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0362 | 0.4268 | 0.5 |
Brugia malayi | MAP kinase sur-1 | 0.0362 | 0.4268 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0362 | 0.4268 | 1 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0362 | 0.4268 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0244 | 0.2751 | 0.6445 |
Plasmodium vivax | SET domain protein, putative | 0.0035 | 0.007 | 1 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0362 | 0.4268 | 0.4238 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0362 | 0.4268 | 1 |
Onchocerca volvulus | 0.0058 | 0.0365 | 0.0947 | |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0362 | 0.4268 | 0.4228 |
Onchocerca volvulus | 0.0278 | 0.3184 | 1 | |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0362 | 0.4268 | 1 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0058 | 0.0365 | 0.0297 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0244 | 0.2751 | 0.6445 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0035 | 0.007 | 0.0017 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0362 | 0.4268 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0362 | 0.4268 | 1 |
Trypanosoma brucei | protein kinase, putative | 0.0362 | 0.4268 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0035 | 0.007 | 0.0164 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0362 | 0.4268 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0362 | 0.4268 | 1 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0362 | 0.4268 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0362 | 0.4268 | 1 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0362 | 0.4268 | 0.4238 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0362 | 0.4268 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0362 | 0.4268 | 0.4228 |
Echinococcus multilocularis | tumor protein p63 | 0.0396 | 0.4703 | 0.4666 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0362 | 0.4268 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0362 | 0.4268 | 0.4228 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0362 | 0.4268 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0035 | 0.007 | 0.0164 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.