Detailed information for compound 1726862

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 416.426 | Formula: C24H20N2O5
  • H donors: 1 H acceptors: 3 LogP: 3.65 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)N1C(=O)[C@H]2[C@@H](C1=O)[C@@H](N(O2)c1ccccc1)c1ccccc1O
  • InChi: 1S/C24H20N2O5/c1-30-17-13-11-15(12-14-17)25-23(28)20-21(18-9-5-6-10-19(18)27)26(31-22(20)24(25)29)16-7-3-2-4-8-16/h2-14,20-22,27H,1H3/t20-,21-,22+/m0/s1
  • InChiKey: YSVKRYZWYMEBMB-FDFHNCONSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Plasmodium falciparum glutathione reductase 0.0046 0.0458 0.102
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0084 0.1171 1
Echinococcus granulosus PHD finger protein rhinoceros 0.0073 0.0972 0.0972
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0153 0.0174
Echinococcus granulosus tubulin alpha 3 chain 0.0196 0.3294 0.3294
Onchocerca volvulus Brd8 homolog 0.0062 0.0763 0.1563
Trypanosoma brucei beta tubulin 0.0259 0.4488 0.9419
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.157 0.8342
Echinococcus multilocularis Tubulin beta 2C chain 0.0259 0.4488 0.4488
Schistosoma mansoni tubulin subunit alpha 0.0196 0.3294 0.4952
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0639 0.0961
Trypanosoma brucei beta tubulin 0.014 0.2243 0.4664
Schistosoma mansoni hypothetical protein 0.0073 0.0972 0.1461
Echinococcus multilocularis tubulin alpha chain 0.0196 0.3294 0.3294
Loa Loa (eye worm) hypothetical protein 0.005 0.0541 0.0813
Trichomonas vaginalis bromodomain-containing protein, putative 0.0261 0.4538 0.9279
Trypanosoma brucei Bromodomain, putative 0.0062 0.0763 0.153
Echinococcus multilocularis PHD finger protein rhinoceros 0.0073 0.0972 0.0972
Trypanosoma cruzi Bromodomain, putative 0.0062 0.0763 0.1557
Giardia lamblia Beta tubulin 0.0259 0.4488 1
Brugia malayi Bromodomain containing protein 0.014 0.2232 0.3824
Leishmania major hypothetical protein, conserved 0.0062 0.0763 0.1557
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Leishmania major DNA-binding protein, putative,predicted bromodomain protein 0.0062 0.0763 0.1557
Loa Loa (eye worm) hypothetical protein 0.0041 0.0365 0.0549
Loa Loa (eye worm) latrophilin receptor protein 2 0.0056 0.0657 0.0987
Echinococcus granulosus bromodomain containing 2 0.0261 0.4538 0.4538
Trypanosoma brucei alpha tubulin 0.0196 0.3294 0.689
Trichomonas vaginalis tubulin beta chain, putative 0.0196 0.3294 0.6692
Schistosoma mansoni enhancer of polycomb 0.0045 0.0434 0.0652
Plasmodium vivax tubulin alpha chain, putative 0.0196 0.3294 0.734
Trichomonas vaginalis conserved hypothetical protein 0.0118 0.1831 0.365
Schistosoma mansoni hypothetical protein 0.0056 0.0657 0.0987
Brugia malayi Latrophilin receptor protein 2 0.0056 0.0657 0.1125
Entamoeba histolytica bromodomain-containing protein 0.0143 0.2296 0.5032
Echinococcus granulosus tubulin alpha 0.014 0.2243 0.2243
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0639 0.0961
Trypanosoma cruzi bromodomain factor 2 protein 0.0062 0.0763 0.1557
Leishmania major beta tubulin 0.0259 0.4488 1
Plasmodium falciparum phd finger protein, putative 0.0073 0.0972 0.2166
Loa Loa (eye worm) hypothetical protein 0.0178 0.2962 0.4453
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0354 0.0577
Echinococcus granulosus enhancer of polycomb 0.0045 0.0434 0.0434
Echinococcus granulosus tubulin gamma 1 chain 0.014 0.2243 0.2243
Trichomonas vaginalis tubulin gamma chain, putative 0.0259 0.4488 0.9174
Loa Loa (eye worm) beta-tubulin 0.0259 0.4488 0.6746
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Schistosoma mansoni enhancer of polycomb 0.0045 0.0434 0.0652
Leishmania major beta tubulin 0.0259 0.4488 1
Schistosoma mansoni transcription initiation factor tfiid 0.0259 0.4483 0.6739
Plasmodium falciparum thioredoxin reductase 0.0046 0.0458 0.102
Echinococcus multilocularis tubulin epsilon chain 0.014 0.2243 0.2243
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0062 0.0763 0.1624
Echinococcus multilocularis Tubulin alpha 1 chain 0.0196 0.3294 0.3294
Loa Loa (eye worm) tubulin gamma chain 0.014 0.2243 0.3372
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Trichomonas vaginalis bromodomain containing protein, putative 0.0062 0.0763 0.1429
Echinococcus multilocularis global transcription activator snf2l2 0.0128 0.2004 0.2004
Giardia lamblia Alpha-tubulin 0.0196 0.3294 0.7294
Trypanosoma cruzi tubulin delta chain 0.0061 0.0742 0.1508
Leishmania major alpha tubulin 0.0196 0.3294 0.7294
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.157 0.8342
Brugia malayi TAZ zinc finger family protein 0.0062 0.0763 0.1308
Trichomonas vaginalis bromodomain containing protein, putative 0.018 0.3005 0.6091
Trichomonas vaginalis bromodomain-containing protein, putative 0.0143 0.2296 0.4616
Echinococcus multilocularis peroxisome assembly protein 26 0.0196 0.3294 0.3294
Leishmania major beta tubulin 0.0259 0.4488 1
Echinococcus granulosus snurportin 1 0.0373 0.6652 0.6652
Trichomonas vaginalis set domain proteins, putative 0.028 0.4885 1
Plasmodium vivax glutathione reductase, putative 0.0046 0.0458 0.102
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0024 0.0041 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Leishmania major beta tubulin 0.0259 0.4488 1
Loa Loa (eye worm) bromodomain containing protein 0.0143 0.2296 0.3452
Giardia lamblia Hypothetical protein 0.0062 0.0763 0.1557
Echinococcus multilocularis tubulin delta chain 0.0061 0.0742 0.0742
Giardia lamblia Gamma tubulin 0.014 0.2243 0.4912
Mycobacterium tuberculosis Probable reductase 0.0105 0.157 0.8342
Brugia malayi MH2 domain containing protein 0.0116 0.1782 0.3053
Toxoplasma gondii alpha tubulin TUBA1 0.0196 0.3294 0.7316
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Echinococcus multilocularis tubulin alpha chain 0.0196 0.3294 0.3294
Schistosoma mansoni phd finger protein 0.0081 0.1124 0.169
Onchocerca volvulus Bromodomain adjacent to zinc finger domain protein 1A homolog 0.0062 0.0763 0.1563
Leishmania major alpha tubulin 0.0196 0.3294 0.7294
Schistosoma mansoni alpha tubulin 0.0196 0.3294 0.4952
Brugia malayi Calcitonin receptor-like protein seb-1 0.0178 0.2962 0.5076
Schistosoma mansoni tubulin subunit delta 0.0061 0.0742 0.1115
Trypanosoma brucei alpha tubulin 0.0196 0.3294 0.689
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0056 0.0657 0.0657
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0116 0.1793 0.3569
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0742 0.1384
Echinococcus granulosus CREB binding protein 0.0062 0.0763 0.0763
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0373 0.6652 1
Loa Loa (eye worm) hypothetical protein 0.0196 0.3294 0.4952
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0134 0.0299
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0084 0.1171 0.6255
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Schistosoma mansoni lipoxygenase 0.0061 0.0739 0.1111
Echinococcus granulosus tubulin alpha chain 0.0196 0.3294 0.3294
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.0788 0.1679
Trypanosoma brucei epsilon tubulin 0.014 0.2243 0.4664
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0153 0.0341
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0102 0.1528 0.3404
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Trichomonas vaginalis bromodomain-containing protein, putative 0.0143 0.2296 0.4616
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Brugia malayi Pre-SET motif family protein 0.0246 0.4242 0.7269
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Echinococcus multilocularis Tubulin beta 2C chain 0.0259 0.4488 0.4488
Schistosoma mansoni hypothetical protein 0.0024 0.0041 0.0062
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0268 0.4662 0.7009
Entamoeba histolytica tubulin alpha-1 chain 0.0196 0.3294 0.7294
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Trichomonas vaginalis conserved hypothetical protein 0.018 0.3005 0.6091
Trichomonas vaginalis tubulin beta chain, putative 0.0196 0.3294 0.6692
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Brugia malayi BRM protein 0.0128 0.2004 0.3433
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Trichomonas vaginalis bromodomain-containing protein, putative 0.0143 0.2296 0.4616
Toxoplasma gondii hypothetical protein 0.0029 0.0134 0.0209
Onchocerca volvulus 0.0035 0.0257 0.0526
Echinococcus granulosus Tubulin beta 2C chain 0.0259 0.4488 0.4488
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0061 0.0739 0.0739
Loa Loa (eye worm) hypothetical protein 0.0135 0.2142 0.322
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Loa Loa (eye worm) CBP-B 0.0062 0.0763 0.1148
Trichomonas vaginalis bromodomain-containing protein, putative 0.018 0.3005 0.6091
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0079 0.1091 0.211
Entamoeba histolytica hypothetical protein 0.0028 0.0126 0.0112
Toxoplasma gondii hypothetical protein 0.0062 0.0763 0.1624
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Plasmodium vivax bromodomain protein, putative 0.0062 0.0763 0.1701
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0061 0.0742 0.1575
Trichomonas vaginalis tubulin, putative 0.0079 0.1091 0.211
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0257 0.0257
Leishmania major beta tubulin 0.0259 0.4488 1
Loa Loa (eye worm) hypothetical protein 0.0062 0.0763 0.1148
Giardia lamblia Beta tubulin 0.0259 0.4488 1
Brugia malayi F/Y-rich N-terminus family protein 0.0027 0.0104 0.0179
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0084 0.1171 0.2609
Leishmania major beta tubulin 0.0259 0.4488 1
Echinococcus granulosus beta tubulin 0.0259 0.4488 0.4488
Toxoplasma gondii beta-tubulin, putative 0.0259 0.4488 1
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0084 0.1171 0.1171
Trichomonas vaginalis tubulin, putative 0.0061 0.0742 0.1384
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0246 0.4242 0.6377
Schistosoma mansoni ran 0.0026 0.0076 0.0115
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Leishmania major beta tubulin 0.0259 0.4488 1
Echinococcus multilocularis beta tubulin 0.0259 0.4488 0.4488
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0062 0.0763 0.1429
Brugia malayi jmjC domain containing protein 0.0049 0.052 0.0891
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0084 0.1171 0.5
Schistosoma mansoni tubulin subunit beta 0.0259 0.4488 0.6746
Echinococcus granulosus tumor protein p63 0.0343 0.6089 0.6089
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0007 0.001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0602 0.0904
Echinococcus granulosus tubulin alpha 3 chain 0.0196 0.3294 0.3294
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0126 0.0103
Trypanosoma cruzi Bromodomain, putative 0.0062 0.0763 0.1557
Trichomonas vaginalis importin beta-1, putative 0.0028 0.0126 0.0103
Brugia malayi Tubulin gamma chain 0.014 0.2243 0.3844
Trichomonas vaginalis bromodomain-containing protein, putative 0.0143 0.2296 0.4616
Echinococcus granulosus geminin 0.02 0.3378 0.3378
Toxoplasma gondii bromodomain-containing protein 0.0062 0.0763 0.1624
Echinococcus granulosus tubulin epsilon chain 0.014 0.2243 0.2243
Loa Loa (eye worm) hypothetical protein 0.0073 0.0972 0.1461
Schistosoma mansoni zinc finger protein 0.008 0.1111 0.1671
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0178 0.2962 0.4453
Leishmania major gamma-tubulin 0.014 0.2243 0.4912
Toxoplasma gondii thioredoxin reductase 0.0046 0.0458 0.0937
Loa Loa (eye worm) tubulin beta chain 0.0259 0.4488 0.6746
Echinococcus multilocularis geminin 0.02 0.3378 0.3378
Mycobacterium leprae cell division protein FtsZ 0.0061 0.0742 0.3666
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Loa Loa (eye worm) hypothetical protein 0.0116 0.1793 0.2695
Trichomonas vaginalis tubulin, putative 0.0079 0.1091 0.211
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.1791 1
Loa Loa (eye worm) tubulin alpha-3 chain 0.0116 0.1793 0.2695
Entamoeba histolytica bromodomain-containing protein 0.0062 0.0763 0.1557
Leishmania major beta tubulin 0.0259 0.4488 1
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0153 0.0341
Echinococcus granulosus bromodomain containing protein 8 0.0062 0.0763 0.0763
Loa Loa (eye worm) tubulin alpha chain 0.0196 0.3294 0.4952
Schistosoma mansoni enhancer of polycomb 0.0045 0.0434 0.0652
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.157 0.8342
Brugia malayi Thioredoxin reductase 0.0046 0.0458 0.0784
Trichomonas vaginalis bromodomain-containing protein, putative 0.0143 0.2296 0.4616
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.157 0.8342
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0026 0.0076 0.0079
Toxoplasma gondii beta-1 tubulin, putative 0.0259 0.4488 1
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0084 0.1171 0.254
Brugia malayi Bromodomain containing protein 0.0261 0.4538 0.7776
Echinococcus multilocularis 0.0259 0.4483 0.4483
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0056 0.0657 0.0657
Schistosoma mansoni bromodomain containing 0.0219 0.3734 0.5614
Trichomonas vaginalis bromodomain-containing protein, putative 0.0143 0.2296 0.4616
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0062 0.0763 0.1429
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0055 0.0626 0.2967
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.0316 0.0316
Schistosoma mansoni hypothetical protein 0.0373 0.6652 1
Leishmania major alpha tubulin 0.0196 0.3294 0.7294
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Echinococcus multilocularis Tubulin alpha 1 chain 0.0196 0.3294 0.3294
Trypanosoma brucei AAA ATPase, putative 0.0273 0.4762 1
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0143 0.2296 0.4616
Echinococcus multilocularis peptidase Clp (S14 family) 0.0055 0.0626 0.0626
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0458 0.0688
Loa Loa (eye worm) hypothetical protein 0.0062 0.0763 0.1148
Leishmania major zeta tubulin, putative 0.0061 0.0742 0.1508
Schistosoma mansoni hypothetical protein 0.0122 0.1895 0.2849
Echinococcus granulosus Tubulin beta 2C chain 0.0259 0.4488 0.4488
Trichomonas vaginalis lymphoid specific helicase, putative 0.0072 0.0962 0.1841
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0056 0.0657 0.0657
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Trypanosoma brucei alpha tubulin 0.0196 0.3294 0.689
Echinococcus granulosus protein kinase C binding protein 1 0.0062 0.0763 0.0763
Loa Loa (eye worm) hypothetical protein 0.0053 0.0602 0.0904
Trichomonas vaginalis bromodomain-containing protein, putative 0.018 0.3005 0.6091
Schistosoma mansoni alpha tubulin 0.0196 0.3294 0.4952
Echinococcus granulosus tubulin alpha chain 0.0196 0.3294 0.3294
Brugia malayi Pre-SET motif family protein 0.0035 0.0257 0.044
Trichomonas vaginalis bromodomain-containing protein, putative 0.0143 0.2296 0.4616
Schistosoma mansoni peptidase Clp (S14 family) 0.0084 0.1171 0.176
Echinococcus multilocularis bromodomain containing protein 7 0.0157 0.2561 0.2561
Leishmania major beta tubulin 0.0259 0.4488 1
Echinococcus multilocularis tubulin alpha 3 chain 0.0196 0.3294 0.3294
Echinococcus multilocularis tubulin alpha chain 0.0196 0.3294 0.3294
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0084 0.1171 0.1171
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Trichomonas vaginalis bromodomain containing protein, putative 0.0062 0.0763 0.1429
Plasmodium vivax hypothetical protein, conserved 0.0062 0.0763 0.1701
Brugia malayi tubulin alpha-2 chain 0.0196 0.3294 0.5644
Brugia malayi glutathione reductase 0.0046 0.0458 0.0784
Trichomonas vaginalis bromodomain containing protein, putative 0.0143 0.2296 0.4616
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0049 0.052 0.052
Echinococcus granulosus alpha tubulin 0.0196 0.3294 0.3294
Echinococcus granulosus enhancer of polycomb 0.0045 0.0434 0.0434
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0055 0.0626 0.1261
Echinococcus granulosus bromodomain containing protein 7 0.0157 0.2561 0.2561
Toxoplasma gondii bromodomain-containing protein 0.0143 0.2296 0.5071
Trypanosoma cruzi tubulin gamma chain 0.014 0.2243 0.4912
Echinococcus granulosus peptidase Clp S14 family 0.0055 0.0626 0.0626
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0153 0.0341
Trichomonas vaginalis tubulin gamma chain, putative 0.014 0.2243 0.4506
Plasmodium falciparum bromodomain protein 1 0.0062 0.0763 0.1701
Schistosoma mansoni alpha tubulin 0.0196 0.3294 0.4952
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Loa Loa (eye worm) bromodomain containing protein 0.009 0.1288 0.1936
Toxoplasma gondii bromodomain-containing protein 0.0062 0.0763 0.1624
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0045 0.0045
Schistosoma mansoni helicase 0.0128 0.2004 0.3012
Trypanosoma cruzi hypothetical protein, conserved 0.0062 0.0763 0.1557
Loa Loa (eye worm) bromodomain containing protein 0.0078 0.1073 0.1613
Echinococcus multilocularis importin subunit beta 1 0.0035 0.0251 0.0251
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Plasmodium vivax tubulin alpha chain, putative 0.0196 0.3294 0.734
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Loa Loa (eye worm) hypothetical protein 0.0062 0.0763 0.1148
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0257 0.0386
Leishmania major beta tubulin 0.0259 0.4488 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.157 0.8342
Brugia malayi Tubulin alpha-2 chain 0.0196 0.3294 0.5644
Echinococcus multilocularis tubulin alpha chain 0.0196 0.3294 0.3294
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0084 0.1171 0.2609
Plasmodium vivax tubulin epsilon chain, putative 0.014 0.2243 0.4999
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.014 0.2243 0.4952
Giardia lamblia Epsilon tubulin 0.0061 0.0742 0.1508
Brugia malayi ATPase, AAA family protein 0.0273 0.4762 0.816
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0458 0.0865
Trypanosoma brucei alpha tubulin, putative 0.0079 0.1091 0.2224
Leishmania major alpha tubulin 0.0196 0.3294 0.7294
Trichomonas vaginalis bromodomain-containing protein, putative 0.018 0.3005 0.6091
Trichomonas vaginalis conserved hypothetical protein 0.0143 0.2296 0.4616
Leishmania major beta tubulin 0.0259 0.4488 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.0316 0.0316
Echinococcus granulosus transcription initiation factor TFIID subunit 1 0.0259 0.4483 0.4483
Trichomonas vaginalis bromodomain-containing protein, putative 0.0143 0.2296 0.4616
Loa Loa (eye worm) tubulin alpha chain 0.0196 0.3294 0.4952
Schistosoma mansoni ran 0.0026 0.0076 0.0115
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.1782 0.2679
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.1791 1
Brugia malayi PHD-finger family protein 0.0086 0.1219 0.2089
Echinococcus granulosus peroxisome assembly protein 26 0.0196 0.3294 0.3294
Brugia malayi Bromodomain containing protein 0.0152 0.2462 0.4218
Trypanosoma brucei beta tubulin 0.0259 0.4488 0.9419
Loa Loa (eye worm) BEN-1 protein 0.0259 0.4488 0.6746
Schistosoma mansoni importin beta-1 0.0035 0.0251 0.0377
Trichomonas vaginalis tubulin epsilon chain, putative 0.0196 0.3294 0.6692
Trichomonas vaginalis bromodomain-containing protein, putative 0.0143 0.2296 0.4616
Loa Loa (eye worm) hypothetical protein 0.0273 0.4762 0.7159
Entamoeba histolytica hypothetical protein 0.0062 0.0763 0.1557
Loa Loa (eye worm) hypothetical protein 0.0035 0.0251 0.0377
Schistosoma mansoni hypothetical protein 0.0211 0.3588 0.5394
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.1782 0.2679
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.157 0.8666
Leishmania major beta tubulin 0.0259 0.4488 1
Trypanosoma cruzi Bromodomain, putative 0.0062 0.0763 0.1557
Plasmodium falciparum tubulin delta chain, putative 0.0061 0.0742 0.1653
Plasmodium falciparum alpha tubulin 1 0.0196 0.3294 0.734
Trypanosoma brucei Bromodomain, putative 0.0062 0.0763 0.153
Trypanosoma brucei zeta tubulin, putative 0.0061 0.0742 0.1484
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0062 0.0763 0.0763
Plasmodium vivax tubulin beta chain, putative 0.0259 0.4488 1
Schistosoma mansoni tubulin subunit alpha 0.0196 0.3294 0.4952
Echinococcus granulosus tubulin beta 1 chain 0.0259 0.4488 0.4488
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0049 0.052 0.052
Echinococcus multilocularis tubulin gamma 1 chain 0.014 0.2243 0.2243
Trypanosoma brucei beta tubulin 0.0259 0.4488 0.9419
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0062 0.0763 0.1429
Trichomonas vaginalis tubulin beta chain, putative 0.0196 0.3294 0.6692
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Echinococcus granulosus CREB binding protein 0.0062 0.0763 0.0763
Schistosoma mansoni tubulin subunit beta 0.0061 0.0742 0.1115
Trichomonas vaginalis tubulin alpha chain, putative 0.0079 0.1091 0.211
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0045 0.0045
Loa Loa (eye worm) tubulin beta-4 chain 0.0259 0.4488 0.6746
Schistosoma mansoni hypothetical protein 0.0062 0.0763 0.1148
Entamoeba histolytica bromodomain-containing protein 0.0152 0.2462 0.5407
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Trichomonas vaginalis tubulin beta chain, putative 0.0259 0.4488 0.9174
Trichomonas vaginalis bromodomain-containing protein, putative 0.0143 0.2296 0.4616
Echinococcus multilocularis tubulin alpha 3 chain 0.0196 0.3294 0.3294
Trichomonas vaginalis tubulin epsilon chain, putative 0.0259 0.4488 0.9174
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0257 0.0386
Leishmania major alpha tubulin 0.0196 0.3294 0.7294
Schistosoma mansoni tubulin subunit alpha 0.0196 0.3294 0.4952
Toxoplasma gondii alpha-tubulin I, putative 0.0196 0.3294 0.7316
Trypanosoma cruzi Bromodomain factor 1 0.0062 0.0763 0.1557
Trichomonas vaginalis bromodomain-containing protein, putative 0.0143 0.2296 0.4616
Brugia malayi acetyltransferase, GNAT family protein 0.0062 0.0763 0.1308
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0062 0.0763 0.1429
Entamoeba histolytica bromodomain-containing protein 0.0143 0.2296 0.5032
Plasmodium vivax SET domain containing protein 0.0063 0.0788 0.1756
Trichomonas vaginalis tubulin beta chain, putative 0.0196 0.3294 0.6692
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Echinococcus multilocularis tubulin subunit beta 0.0259 0.4488 0.4488
Leishmania major alpha tubulin 0.0196 0.3294 0.7294
Brugia malayi bromodomain containing protein 0.0062 0.0763 0.1308
Mycobacterium tuberculosis Cell division protein FtsZ 0.0061 0.0742 0.2129
Plasmodium falciparum alpha tubulin 2 0.0196 0.3294 0.734
Onchocerca volvulus 0.0062 0.0763 0.1563
Loa Loa (eye worm) tubulin alpha 2 0.0135 0.2142 0.322
Brugia malayi AF-10 protein 0.0024 0.0041 0.0071
Schistosoma mansoni SET domain protein 0.0022 0.0014 0.0021
Trypanosoma cruzi ATPase, putative 0.0211 0.3588 0.7961
Schistosoma mansoni bromodomain-containing protein 3 brd3 0.0261 0.4538 0.6822
Plasmodium falciparum tubulin beta chain 0.0259 0.4488 1
Echinococcus multilocularis bromodomain containing 2 0.0261 0.4538 0.4538
Echinococcus multilocularis polybromo 1 0.0062 0.0763 0.0763
Echinococcus granulosus Tubulin beta 2C chain 0.0259 0.4488 0.4488
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0066 0.0099
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0061 0.0742 0.1384
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0084 0.1171 1
Trichomonas vaginalis bromodomain-containing protein 4, brd4, putative 0.0143 0.2296 0.4616
Leishmania major beta tubulin 0.0259 0.4488 1
Entamoeba histolytica bromodomain-containing protein 0.0143 0.2296 0.5032
Echinococcus granulosus tubulin delta chain 0.0061 0.0742 0.0742
Trichomonas vaginalis bromodomain-containing protein, putative 0.0143 0.2296 0.4616
Trichomonas vaginalis bromodomain containing protein, putative 0.0062 0.0763 0.1429
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Treponema pallidum cell division protein FtsZ 0.0061 0.0742 0.5861
Brugia malayi latrophilin 2 splice variant baaae 0.0122 0.1895 0.3247
Brugia malayi Cell division protein ftsZ 0.0061 0.0742 0.1271
Brugia malayi Tubulin beta-1 chain 0.0259 0.4488 0.769
Schistosoma mansoni tubulin subunit gamma 0.014 0.2243 0.3372
Onchocerca volvulus 0.005 0.0541 0.1107
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Echinococcus granulosus tubulin alpha 1C chain 0.0196 0.3294 0.3294
Echinococcus granulosus tubulin alpha 1C chain 0.0196 0.3294 0.3294
Giardia lamblia Hypothetical protein 0.0062 0.0763 0.1557
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0251 0.0444
Echinococcus granulosus importin subunit beta 1 0.0035 0.0251 0.0251
Onchocerca volvulus Alhambra homolog 0.0073 0.0972 0.1989
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0354 0.0577
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0026 0.0076 0.0131
Loa Loa (eye worm) PHD-finger family protein 0.0073 0.0972 0.1461
Trichomonas vaginalis bromodomain-containing protein, putative 0.0143 0.2296 0.4616
Schistosoma mansoni hypothetical protein 0.0022 0.0007 0.001
Brugia malayi Tubulin beta chain 0.0061 0.0742 0.1271
Echinococcus granulosus zinc finger protein 0.008 0.1111 0.1111
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0972 0.2166
Echinococcus multilocularis Bromodomain containing protein 0.0143 0.2296 0.2296
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0458 0.102
Leishmania major hypothetical protein, conserved 0.003 0.0153 0.0174
Leishmania major alpha tubulin 0.0196 0.3294 0.7294
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Plasmodium vivax delta tubulin, putative 0.0061 0.0742 0.1653
Loa Loa (eye worm) hypothetical protein 0.015 0.2436 0.3661
Trichomonas vaginalis tubulin epsilon chain, putative 0.0061 0.0742 0.1384
Leishmania major beta tubulin 0.0259 0.4488 1
Echinococcus granulosus GTP binding nuclear protein Ran 0.0026 0.0076 0.0076
Brugia malayi hypothetical protein 0.0081 0.1122 0.1923
Trypanosoma brucei tubulin gamma chain 0.014 0.2243 0.4664
Brugia malayi Bromodomain containing protein 0.033 0.5836 1
Schistosoma mansoni hypothetical protein 0.0056 0.0657 0.0987
Brugia malayi Bromodomain containing protein 0.0261 0.4538 0.7776
Onchocerca volvulus 0.0143 0.2296 0.47
Loa Loa (eye worm) acetyltransferase 0.0062 0.0763 0.1148
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Schistosoma mansoni hypothetical protein 0.0056 0.0657 0.0987
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Trypanosoma brucei Bromodomain, putative 0.0062 0.0763 0.153
Echinococcus granulosus tubulin beta 4A class IVa 0.0259 0.4488 0.4488
Trypanosoma brucei epsilon tubulin 0.014 0.2243 0.4664
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Plasmodium vivax bromodomain protein, putative 0.0062 0.0763 0.1701
Trypanosoma brucei tubulin delta chain 0.0061 0.0742 0.1484
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Echinococcus granulosus histone acetyltransferase KAT2B 0.0062 0.0763 0.0763
Brugia malayi Bromodomain containing protein 0.0062 0.0763 0.1308
Trichomonas vaginalis bromodomain-containing protein, putative 0.0143 0.2296 0.4616
Brugia malayi Tubulin beta chain 0.0079 0.1091 0.1869
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0178 0.2962 0.5076
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0055 0.0626 0.1261
Brugia malayi Tubulin alpha chain 0.0196 0.3294 0.5644
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Loa Loa (eye worm) tubulin beta-2A chain 0.0259 0.4488 0.6746
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0196 0.3294 0.6692
Trichomonas vaginalis conserved hypothetical protein 0.015 0.2436 0.4906
Toxoplasma gondii beta tubulin 0.0259 0.4488 1
Echinococcus granulosus beta tubulin 0.0259 0.4488 0.4488
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Brugia malayi Probable ClpP-like protease 0.0084 0.1171 0.2006
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0056 0.0657 0.1125
Schistosoma mansoni hypothetical protein 0.0062 0.0763 0.1148
Loa Loa (eye worm) hypothetical protein 0.0026 0.008 0.012
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0458 0.0458
Schistosoma mansoni enhancer of polycomb 0.0045 0.0434 0.0652
Plasmodium vivax bromodomain protein, putative 0.0062 0.0763 0.1701
Echinococcus granulosus Bromodomain containing protein 0.0062 0.0763 0.0763
Echinococcus granulosus global transcription activator snf2l2 0.0128 0.2004 0.2004
Echinococcus granulosus Tubulin alpha 1 chain 0.0196 0.3294 0.3294
Schistosoma mansoni tubulin subunit beta 0.0259 0.4488 0.6746
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0062 0.0763 0.1701
Brugia malayi RNA, U transporter 1 0.0099 0.1471 0.252
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Entamoeba histolytica ankyrin repeat protein, putative 0.0062 0.0763 0.1557
Leishmania major alpha tubulin 0.0196 0.3294 0.7294
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0026 0.0076 0.017
Trypanosoma brucei bromodomain factor 2 protein, putative 0.0062 0.0763 0.153
Echinococcus multilocularis Tubulin beta 2C chain 0.0259 0.4488 0.4488
Loa Loa (eye worm) hypothetical protein 0.0062 0.0763 0.1148
Echinococcus granulosus peregrin 0.0349 0.6197 0.6197
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0084 0.1171 1
Leishmania major beta tubulin 0.0259 0.4488 1
Echinococcus granulosus Tubulin beta 2C chain 0.0259 0.4488 0.4488
Schistosoma mansoni polybromo-1 0.0062 0.0763 0.1148
Trichomonas vaginalis bromodomain containing protein, putative 0.0062 0.0763 0.1429
Leishmania major hypothetical protein, conserved,predicted bromodomain protein 0.0062 0.0763 0.1557
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0126 0.0103
Giardia lamblia Delta tubulin 0.0061 0.0742 0.1508
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Schistosoma mansoni tubulin subunit beta 0.0259 0.4488 0.6746
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Loa Loa (eye worm) hypothetical protein 0.0103 0.1539 0.2314
Trichomonas vaginalis hypothetical protein 0.0062 0.0763 0.1429
Entamoeba histolytica tubulin alpha chain, putative 0.0196 0.3294 0.7294
Brugia malayi hypothetical protein 0.003 0.0153 0.0262
Leishmania major importin beta-1 subunit, putative 0.0028 0.0126 0.0112
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0084 0.1171 1
Giardia lamblia PHD finger protein 15 0.0073 0.0972 0.203
Schistosoma mansoni hypothetical protein 0.0157 0.2561 0.3849
Loa Loa (eye worm) tubulin alpha-2 chain 0.0196 0.3294 0.4952
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0034 0.0232 0.0232
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0639 0.0639
Trichomonas vaginalis tubulin beta chain, putative 0.0079 0.1091 0.211
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.1791 1
Brugia malayi Importin beta-1 subunit 0.0035 0.0251 0.043
Brugia malayi beta-tubulin, identical 0.0259 0.4488 0.769
Echinococcus multilocularis peregrin 0.0349 0.6197 0.6197
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0123 0.1923 0.1923
Loa Loa (eye worm) hypothetical protein 0.0122 0.1895 0.2849
Echinococcus granulosus Tubulin alpha 1 chain 0.0196 0.3294 0.3294
Loa Loa (eye worm) tubulin beta chain 0.0061 0.0742 0.1115
Giardia lamblia Kinase, putative 0.0143 0.2296 0.5032
Giardia lamblia Beta tubulin 0.0259 0.4488 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0143 0.2296 0.4616
Echinococcus granulosus polybromo 1 0.0062 0.0763 0.0763
Plasmodium vivax tubulin gamma chain, putative 0.014 0.2243 0.4999
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Trypanosoma cruzi Bromodomain, putative 0.0062 0.0763 0.1557
Trypanosoma cruzi epsilon tubulin, putative 0.014 0.2243 0.4912
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0084 0.1171 0.5
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0153 0.0251
Trypanosoma brucei epsilon tubulin 0.014 0.2243 0.4664
Leishmania major alpha tubulin 0.0196 0.3294 0.7294
Loa Loa (eye worm) hypothetical protein 0.0064 0.0802 0.1206
Brugia malayi Tubulin alpha-2 chain 0.0196 0.3294 0.5644
Loa Loa (eye worm) alpha-tubulin 0.0196 0.3294 0.4952
Toxoplasma gondii PHD-finger domain-containing protein 0.0073 0.0972 0.2093
Echinococcus multilocularis tubulin subunit TubB 0.0196 0.3294 0.3294
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Trypanosoma cruzi Bromodomain, putative 0.0062 0.0763 0.1557
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Echinococcus multilocularis tubulin alpha 1C chain 0.0196 0.3294 0.3294
Trichomonas vaginalis hypothetical protein 0.0062 0.0763 0.1429
Loa Loa (eye worm) hypothetical protein 0.0084 0.1171 0.176
Trypanosoma cruzi bromodomain-containing protein 3 0.0062 0.0763 0.1557
Echinococcus granulosus tubulin subunit TubB 0.0196 0.3294 0.3294
Trichomonas vaginalis bromodomain-containing protein, putative 0.0143 0.2296 0.4616
Onchocerca volvulus 0.028 0.4885 1
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0026 0.0076 0.017
Trichomonas vaginalis bromodomain-containing protein, putative 0.0143 0.2296 0.4616
Schistosoma mansoni tubulin subunit beta 0.0259 0.4488 0.6746
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0045 0.0068
Trichomonas vaginalis bromodomain-containing protein, putative 0.0152 0.2462 0.496
Trypanosoma cruzi tubulin delta chain 0.0061 0.0742 0.1508
Trichomonas vaginalis tubulin epsilon chain, putative 0.0259 0.4488 0.9174
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0639 0.0639
Echinococcus granulosus ATPase family AAA domain containing protein 2B 0.0273 0.4762 0.4762
Echinococcus multilocularis beta tubulin 0.0259 0.4488 0.4488
Echinococcus multilocularis ATPase family AAA domain containing protein 2B 0.0273 0.4762 0.4762
Brugia malayi PHD-finger family protein 0.0073 0.0972 0.1665
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0029 0.0134 0.0299
Schistosoma mansoni hypothetical protein 0.0062 0.0763 0.1148
Toxoplasma gondii PHD-finger domain-containing protein 0.0073 0.0972 0.2093
Onchocerca volvulus 0.0062 0.0763 0.1563
Echinococcus granulosus tubulin subunit beta 0.0259 0.4488 0.4488
Trichomonas vaginalis tubulin beta chain, putative 0.0196 0.3294 0.6692
Schistosoma mansoni CREB-binding protein 2 0.0062 0.0763 0.1148
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0458 0.0458
Echinococcus multilocularis Tubulin beta 2C chain 0.0259 0.4488 0.4488
Trichomonas vaginalis tubulin alpha chain, putative 0.0079 0.1091 0.211
Schistosoma mansoni tubulin subunit beta 0.0259 0.4488 0.6746
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0084 0.1171 0.254
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0123 0.1923 0.1923
Entamoeba histolytica tubulin family protein 0.0259 0.4488 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0639 0.0639
Loa Loa (eye worm) hypothetical protein 0.0056 0.0657 0.0987
Plasmodium falciparum tubulin gamma chain 0.014 0.2243 0.4999
Loa Loa (eye worm) glutathione reductase 0.0046 0.0458 0.0688
Brugia malayi alpha-tubulin 0.0196 0.3294 0.5644
Trichomonas vaginalis tubulin beta chain, putative 0.0196 0.3294 0.6692
Plasmodium falciparum bromodomain protein 2, putative 0.0062 0.0763 0.1701
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.1791 1
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0062 0.0763 0.1429
Trichomonas vaginalis bromodomain-containing protein 3, brd3, putative 0.0062 0.0763 0.1429
Leishmania major beta tubulin 0.0259 0.4488 1
Echinococcus multilocularis zinc finger protein 0.008 0.1111 0.1111
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0639 0.1095
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0061 0.0739 0.0739
Schistosoma mansoni hypothetical protein 0.02 0.3378 0.5078
Echinococcus multilocularis tubulin alpha 0.014 0.2243 0.2243
Brugia malayi Bromodomain containing protein 0.0062 0.0763 0.1308
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.0602 0.0904
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Trichomonas vaginalis bromodomain-containing protein, putative 0.0143 0.2296 0.4616
Echinococcus granulosus PH interacting protein 0.0062 0.0763 0.0763
Trypanosoma brucei zeta tubulin 0.0061 0.0742 0.1484
Echinococcus granulosus Tubulin beta 2C chain 0.0259 0.4488 0.4488
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0135 0.2142 0.4296
Trichomonas vaginalis tubulin gamma chain, putative 0.014 0.2243 0.4506
Trypanosoma brucei beta tubulin 0.0259 0.4488 0.9419
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0026 0.0076 0.0076
Schistosoma mansoni tubulin subunit beta 0.0259 0.4488 0.6746
Loa Loa (eye worm) BRM protein 0.0095 0.1388 0.2087
Loa Loa (eye worm) BRM protein 0.0043 0.0403 0.0606
Entamoeba histolytica bromodomain-containing protein 0.0062 0.0763 0.1557
Loa Loa (eye worm) hypothetical protein 0.0111 0.1697 0.2551
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0639 0.0961
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Echinococcus multilocularis snurportin 1 0.0373 0.6652 0.6652
Trichomonas vaginalis tubulin alpha chain, putative 0.0079 0.1091 0.211
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0742 0.1384
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0135 0.2142 0.322
Loa Loa (eye worm) BEN-1 protein 0.0259 0.4488 0.6746
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0026 0.0076 0.0115
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0062 0.0763 0.1624
Leishmania major delta tubulin, putative 0.0061 0.0742 0.1508
Trichomonas vaginalis bromodomain-containing protein, putative 0.0143 0.2296 0.4616
Echinococcus multilocularis CREB binding protein 0.0062 0.0763 0.0763
Plasmodium falciparum tubulin epsilon chain, putative 0.014 0.2243 0.4999
Leishmania major beta tubulin 0.0259 0.4488 1
Trichomonas vaginalis conserved hypothetical protein 0.009 0.1288 0.2519
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0041 0.0092
Echinococcus multilocularis hypothetical protein 0.0196 0.3294 0.3294
Schistosoma mansoni hypothetical protein 0.0062 0.0763 0.1148
Echinococcus granulosus tubulin alpha chain 0.0196 0.3294 0.3294
Loa Loa (eye worm) alpha-tubulin 0.0196 0.3294 0.4952
Giardia lamblia Alpha-tubulin 0.0196 0.3294 0.7294
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0523 0.0929
Schistosoma mansoni hypothetical protein 0.0056 0.0657 0.0987
Echinococcus multilocularis bromodomain containing protein 8 0.0062 0.0763 0.0763
Echinococcus granulosus GPCR family 2 0.0056 0.0657 0.0657
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Trypanosoma brucei Bromodomain factor 1 0.0062 0.0763 0.153
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Trypanosoma brucei trypanothione reductase 0.0046 0.0458 0.0882
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0639 0.0639
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0153 0.0237
Loa Loa (eye worm) hypothetical protein 0.0219 0.3734 0.5614
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0639 0.0961
Leishmania major beta tubulin 0.0259 0.4488 1
Toxoplasma gondii bromodomain-containing protein 0.0062 0.0763 0.1624
Trichomonas vaginalis tubulin, putative 0.0259 0.4488 0.9174
Leishmania major alpha tubulin 0.0196 0.3294 0.7294
Trichomonas vaginalis tubulin epsilon chain, putative 0.0196 0.3294 0.6692
Brugia malayi polybromodomain protein 0.0062 0.0763 0.1308
Entamoeba histolytica tubulin gamma chain 0.014 0.2243 0.4912
Echinococcus multilocularis tumor protein p63 0.0343 0.6089 0.6089
Trichomonas vaginalis bromodomain-containing protein, putative 0.0261 0.4538 0.9279
Echinococcus multilocularis enhancer of polycomb 0.0045 0.0434 0.0434
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Trypanosoma brucei alpha tubulin 0.0196 0.3294 0.689
Echinococcus multilocularis tubulin beta 1 chain 0.0259 0.4488 0.4488
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0259 0.4488 0.4488
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Echinococcus multilocularis GPCR, family 2 0.0056 0.0657 0.0657
Leishmania major hypothetical protein, conserved 0.0062 0.0763 0.1557
Trypanosoma cruzi beta tubulin, putative 0.0259 0.4488 1
Trichomonas vaginalis tubulin alpha chain, putative 0.014 0.2243 0.4506
Leishmania major alpha tubulin 0.0196 0.3294 0.7294
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0062 0.0763 0.1148
Echinococcus granulosus tubulin alpha chain 0.0196 0.3294 0.3294
Echinococcus granulosus tubulin alpha chain 0.0196 0.3294 0.3294
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0153 0.0174
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0061 0.0742 0.1575
Loa Loa (eye worm) hypothetical protein 0.0261 0.4538 0.6822
Loa Loa (eye worm) hypothetical protein 0.0076 0.1019 0.1533
Trichomonas vaginalis tubulin alpha chain, putative 0.0259 0.4488 0.9174
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.0126 0.0112
Leishmania major epsilon tubulin, putative 0.014 0.2243 0.4912
Toxoplasma gondii histone acetyltransferase TAF1/250 0.0102 0.1528 0.3343
Onchocerca volvulus 0.0079 0.1091 0.2233
Schistosoma mansoni bromodomain containing protein 0.0062 0.0763 0.1148
Entamoeba histolytica tubulin family protein 0.0259 0.4488 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0053 0.0602 0.0602
Trypanosoma cruzi zeta tubulin, putative 0.0061 0.0742 0.1508
Echinococcus multilocularis PH interacting protein 0.0062 0.0763 0.0763
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0251 0.0444
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Trypanosoma cruzi epsilon tubulin, putative 0.014 0.2243 0.4912
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0072 0.0962 0.207
Brugia malayi Bromodomain containing protein 0.0219 0.3734 0.6399
Schistosoma mansoni bromodomain containing protein 0.0127 0.1995 0.2999
Brugia malayi Bromodomain containing protein 0.0062 0.0763 0.1308
Echinococcus multilocularis tubulin alpha chain 0.0196 0.3294 0.3294
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Trypanosoma cruzi alpha tubulin, putative 0.0196 0.3294 0.7294
Echinococcus multilocularis tubulin alpha 1C chain 0.0196 0.3294 0.3294
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0026 0.0076 0.0074
Toxoplasma gondii bromodomain-containing protein 0.0062 0.0763 0.1624
Loa Loa (eye worm) hypothetical protein 0.0105 0.1578 0.2372
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Echinococcus multilocularis protein kinase C binding protein 1 0.0062 0.0763 0.0763
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0062 0.0763 0.1148
Leishmania major trypanothione reductase 0.0046 0.0458 0.0865
Giardia lamblia Transcription regulatory protein SNF2 0.0062 0.0763 0.1557
Schistosoma mansoni tubulin subunit alpha 0.0061 0.0742 0.1115
Trypanosoma cruzi zeta tubulin, putative 0.0061 0.0742 0.1508
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0056 0.0657 0.0657
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Echinococcus multilocularis enhancer of polycomb 0.0045 0.0434 0.0434
Brugia malayi Tubulin alpha chain 0.0061 0.0742 0.1271
Loa Loa (eye worm) tubulin alpha 2 0.0056 0.064 0.0963
Loa Loa (eye worm) tubulin beta-1 chain 0.0259 0.4488 0.6746
Trichomonas vaginalis bromodomain-containing protein, putative 0.0062 0.0763 0.1429
Plasmodium vivax importin-beta 2, putative 0.0035 0.0251 0.0559
Trichomonas vaginalis bromodomain and PHD finger-containing protein, putative 0.0062 0.0763 0.1429
Leishmania major alpha tubulin 0.0196 0.3294 0.7294
Leishmania major ATPase, putative 0.0211 0.3588 0.7961
Echinococcus multilocularis Tubulin alpha 1 chain 0.0196 0.3294 0.3294
Trichomonas vaginalis transcription initiation factor tfiid, putative 0.009 0.1288 0.2519
Brugia malayi polybromodomain protein 0.0062 0.0763 0.1308
Echinococcus granulosus Tubulin alpha 1 chain 0.0196 0.3294 0.3294
Schistosoma mansoni hypothetical protein 0.02 0.3378 0.5078
Loa Loa (eye worm) tubulin alpha 2 0.0135 0.2142 0.322
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0062 0.0763 0.1429
Echinococcus multilocularis Tubulin beta 2C chain 0.0259 0.4488 0.4488
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Brugia malayi Bromodomain containing protein 0.01 0.149 0.2553
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Brugia malayi tubulin alpha chain - mouse 0.0196 0.3294 0.5644
Echinococcus granulosus histone lysine methyltransferase setb 0.0053 0.0602 0.0602
Schistosoma mansoni bromodomain containing protein 0.0064 0.0802 0.1206
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0763 0.1429
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0257 0.0485
Trichomonas vaginalis tubulin gamma chain, putative 0.0061 0.0742 0.1384
Schistosoma mansoni tubulin subunit epsilon 0.014 0.2243 0.3372
Brugia malayi PHD-finger family protein 0.0026 0.008 0.0137
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.0251 0.0472
Loa Loa (eye worm) jmjC domain-containing protein 0.0049 0.052 0.0782
Loa Loa (eye worm) hypothetical protein 0.003 0.0153 0.023
Plasmodium falciparum importin beta, putative 0.0035 0.0251 0.0559
Plasmodium falciparum bromodomain protein, putative 0.0062 0.0763 0.1701
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0541 0.0813
Plasmodium vivax SET domain protein, putative 0.0035 0.0257 0.0572

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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