Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Melatonin receptor type 1A | 0.0017 | 0.0014 | 0.0018 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0039 | 0.0301 | 0.0536 |
Echinococcus multilocularis | thymidylate synthase | 0.0105 | 0.1161 | 0.1157 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0042 | 0.0347 | 0.0619 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | sulfakinin receptor protein | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | histamine h1 receptor | 0.0017 | 0.0014 | 0.001 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.005 | 0.0446 | 0.1049 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0105 | 0.1158 | 0.2081 |
Trypanosoma brucei | trypanothione reductase | 0.0046 | 0.0394 | 0.0925 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0017 | 0.0014 | 0.001 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0105 | 0.1168 | 1 |
Toxoplasma gondii | thioredoxin reductase | 0.0046 | 0.0394 | 0.0925 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0017 | 0.0014 | 0.001 |
Trypanosoma cruzi | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0062 | 0.0607 | 0.1432 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0734 | 0.073 |
Brugia malayi | G-protein coupled receptor | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0083 | 0.0878 | 0.0875 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | allatostatin A receptor | 0.0017 | 0.0014 | 0.001 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0042 | 0.0347 | 0.0619 |
Leishmania major | trypanothione reductase | 0.0046 | 0.0394 | 0.0925 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.003 | 0.0048 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0105 | 0.1168 | 0.1165 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Schistosoma mansoni | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Leishmania major | hypothetical protein, conserved | 0.0042 | 0.0347 | 0.0814 |
Echinococcus granulosus | serotonin receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.003 | 0.0027 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | thymidylate synthase | 0.0105 | 0.1161 | 0.2086 |
Echinococcus multilocularis | dihydrofolate reductase | 0.0442 | 0.5549 | 0.5547 |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.0028 | 0.0168 | 0.0388 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0042 | 0.0347 | 0.2946 |
Brugia malayi | dihydrofolate reductase family protein | 0.0442 | 0.5549 | 1 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.034 | 0.4218 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.003 | 0.0027 |
Mycobacterium ulcerans | lipase LipD | 0.0042 | 0.0347 | 0.0619 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0046 | 0.0394 | 0.0686 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | phosphofructokinase | 0.0105 | 0.1168 | 0.2085 |
Brugia malayi | Serotonin receptor | 0.0017 | 0.0014 | 0.0018 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0042 | 0.0347 | 0.0814 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.034 | 0.4218 | 1 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0004 | 0.0005 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0105 | 0.1158 | 0.1558 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0042 | 0.0347 | 0.0619 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0878 | 0.7104 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Echinococcus multilocularis | uridine 5' monophosphate synthase | 0.0062 | 0.0607 | 0.0604 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0017 | 0.0014 | 0.0018 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Trypanosoma brucei | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0062 | 0.0607 | 0.1432 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0017 | 0.0014 | 0.001 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0116 | 0.1309 | 0.2354 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0004 | 0.0005 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0734 | 0.073 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.003 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | putative neuropeptide receptor | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | beta-lactamase | 0.0042 | 0.0347 | 0.0619 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | orexin receptor type 2 | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | phosphofructokinase | 0.0105 | 0.1168 | 0.21 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0017 | 0.0014 | 0.001 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0028 | 0.0168 | 0.1434 |
Trichomonas vaginalis | 6-phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Onchocerca volvulus | 0.0042 | 0.0347 | 0.0467 | |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0017 | 0.0014 | 0.001 |
Plasmodium vivax | orotidine 5'-phosphate decarboxylase, putative | 0.0062 | 0.0607 | 0.1432 |
Brugia malayi | Dopamine receptor protein 1 | 0.0017 | 0.0014 | 0.0018 |
Plasmodium falciparum | thioredoxin reductase | 0.0046 | 0.0394 | 0.0925 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | orotate phosphoribosyltransferase family protein | 0.0062 | 0.0607 | 0.1088 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.003 | 0.0027 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | hypothetical protein | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0072 | 0.0734 | 0.1316 |
Trichomonas vaginalis | conserved hypothetical protein | 0.005 | 0.0446 | 0.3796 |
Echinococcus multilocularis | allatostatin A receptor | 0.0017 | 0.0014 | 0.001 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0046 | 0.0394 | 0.0925 |
Schistosoma mansoni | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | RNA binding protein | 0.0072 | 0.0734 | 0.13 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.0347 | 0.2946 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | hypothetical protein | 0.0083 | 0.0878 | 0.1577 |
Leishmania major | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative,OMPDCase-OPRTase, putative | 0.0062 | 0.0607 | 0.1432 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0017 | 0.0014 | 0.001 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0105 | 0.1168 | 0.2763 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0017 | 0.0014 | 0.001 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0105 | 0.1168 | 0.2763 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.0442 | 0.5549 | 1 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0017 | 0.0014 | 0.001 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0028 | 0.0168 | 0.0295 |
Brugia malayi | G-protein coupled receptor | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.0442 | 0.5549 | 1 |
Trypanosoma cruzi | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0062 | 0.0607 | 0.1432 |
Brugia malayi | larval opioid receptor | 0.0017 | 0.0014 | 0.0018 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0042 | 0.0347 | 0.0619 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0042 | 0.0347 | 0.0343 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0017 | 0.0014 | 0.001 |
Onchocerca volvulus | 0.0042 | 0.0347 | 0.0467 | |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Toxoplasma gondii | O-linked N-acetylglucosamine transferase | 0.0039 | 0.031 | 0.0727 |
Schistosoma mansoni | biogenic amine receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0017 | 0.0014 | 0.001 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0116 | 0.1309 | 0.185 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.003 | 0.0027 |
Brugia malayi | neuropeptide F receptor | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.0347 | 0.2946 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0017 | 0.0014 | 0.001 |
Treponema pallidum | NADH oxidase | 0.0016 | 0.0004 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0028 | 0.0168 | 0.0388 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.034 | 0.4218 | 1 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0017 | 0.0014 | 0.001 |
Plasmodium vivax | glutathione reductase, putative | 0.0046 | 0.0394 | 0.0925 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.164 | 0.2938 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0534 | 0.094 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0105 | 0.1168 | 0.1579 |
Brugia malayi | Dopamine receptor | 0.0017 | 0.0014 | 0.0018 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0878 | 0.7104 |
Echinococcus granulosus | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0717 | 0.1271 |
Echinococcus granulosus | GPCR family 2 | 0.0018 | 0.003 | 0.0027 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0017 | 0.0014 | 0.001 |
Onchocerca volvulus | 0.0564 | 0.7138 | 1 | |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.2085 |
Echinococcus granulosus | thymidylate synthase | 0.0105 | 0.1161 | 0.1157 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0017 | 0.0014 | 0.001 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Giardia lamblia | O-linked GlcNAc transferase | 0.0023 | 0.0097 | 0.3055 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0042 | 0.0347 | 0.0619 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0028 | 0.0168 | 0.5346 |
Brugia malayi | RE15519p | 0.0017 | 0.0014 | 0.0018 |
Loa Loa (eye worm) | TAR-binding protein | 0.0072 | 0.0734 | 0.13 |
Echinococcus granulosus | somatostatin receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0017 | 0.0014 | 0.001 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.034 | 0.4218 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.027 | 0.3309 | 0.5961 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0057 | 0.0534 | 0.0956 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0046 | 0.0394 | 0.039 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0042 | 0.0347 | 0.0814 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0105 | 0.1158 | 0.2081 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.003 | 0.0027 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0017 | 0.0014 | 0.001 |
Onchocerca volvulus | 0.0042 | 0.0347 | 0.0467 | |
Echinococcus multilocularis | fmrfamide receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0017 | 0.0014 | 0.001 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0028 | 0.0168 | 0.0388 |
Brugia malayi | ORL1-like opioid receptor | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0057 | 0.0534 | 0.0956 |
Mycobacterium ulcerans | hypothetical protein | 0.0042 | 0.0347 | 0.0619 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | Amyloid A4 extracellular domain containing protein | 0.0334 | 0.415 | 0.7477 |
Brugia malayi | AKH receptor | 0.0017 | 0.0014 | 0.0018 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0017 | 0.0014 | 0.001 |
Wolbachia endosymbiont of Brugia malayi | orotidine-5'-phosphate decarboxylase | 0.0626 | 0.7948 | 1 |
Toxoplasma gondii | phosphofructokinase PFKII | 0.0028 | 0.0168 | 0.0388 |
Loa Loa (eye worm) | glutathione reductase | 0.0046 | 0.0394 | 0.0686 |
Echinococcus multilocularis | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | Dopamine receptor protein 2 | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | adenoreceptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | O glycosyltransferase | 0.004 | 0.0316 | 0.0312 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0116 | 0.1309 | 0.2354 |
Giardia lamblia | O-linked GlcNAc transferase | 0.0039 | 0.031 | 1 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Echinococcus multilocularis | fmrfamide receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.0347 | 0.0619 |
Brugia malayi | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.21 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0046 | 0.0394 | 0.0925 |
Brugia malayi | follicle stimulating hormone receptor | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | beta-lactamase family protein | 0.0042 | 0.0347 | 0.0619 |
Brugia malayi | hypothetical protein | 0.005 | 0.0446 | 0.0797 |
Echinococcus multilocularis | somatostatin receptor | 0.0017 | 0.0014 | 0.001 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0105 | 0.1168 | 0.2763 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | biogenic amine receptor | 0.0017 | 0.0014 | 0.001 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0878 | 0.7104 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0042 | 0.0347 | 0.0343 |
Echinococcus granulosus | fmrfamide receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0734 | 0.073 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | opsin-like receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.21 |
Plasmodium falciparum | glutathione reductase | 0.0046 | 0.0394 | 0.0925 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0105 | 0.1161 | 0.1157 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0057 | 0.0534 | 0.094 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0105 | 0.1161 | 0.2086 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | glutathione reductase | 0.0046 | 0.0394 | 0.0703 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0042 | 0.0347 | 0.0601 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0046 | 0.0394 | 0.0703 |
Echinococcus granulosus | tar DNA binding protein | 0.0072 | 0.0734 | 0.073 |
Schistosoma mansoni | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.2085 |
Echinococcus multilocularis | tar DNA binding protein | 0.0072 | 0.0734 | 0.073 |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.0347 | 0.0619 |
Schistosoma mansoni | o-linked n-acetylglucosamine transferase ogt | 0.004 | 0.0316 | 0.0312 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | g-protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | O glycosyltransferase | 0.004 | 0.0316 | 0.0312 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0028 | 0.0168 | 0.0388 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0042 | 0.0347 | 0.0619 |
Schistosoma mansoni | opsin-like receptor | 0.0017 | 0.0014 | 0.001 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0878 | 0.7104 |
Loa Loa (eye worm) | UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase | 0.004 | 0.0314 | 0.0542 |
Brugia malayi | Dihydrofolate reductase | 0.0442 | 0.5549 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0042 | 0.0347 | 0.0619 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Brugia malayi | neuropeptide F receptor | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0014 | 0.001 |
Mycobacterium ulcerans | orotidine 5'-phosphate decarboxylase | 0.0062 | 0.0607 | 0.1088 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0083 | 0.0878 | 0.0875 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Toxoplasma gondii | ABC1 family protein | 0.0042 | 0.0347 | 0.0814 |
Schistosoma mansoni | dihydrofolate reductase | 0.0442 | 0.5549 | 0.5547 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0105 | 0.1161 | 0.1564 |
Schistosoma mansoni | alzheimer's disease beta-amyloid related | 0.0122 | 0.1384 | 0.1381 |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.0347 | 0.0619 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0017 | 0.0014 | 0.001 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0028 | 0.0168 | 0.0295 |
Mycobacterium ulcerans | beta-lactamase | 0.0042 | 0.0347 | 0.0619 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.0878 | 0.0875 |
Chlamydia trachomatis | dihydrofolate reductase | 0.0442 | 0.5549 | 1 |
Echinococcus multilocularis | serotonin receptor | 0.0017 | 0.0014 | 0.001 |
Toxoplasma gondii | 6-phosphofructokinase | 0.0028 | 0.0168 | 0.0388 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0105 | 0.1158 | 0.2081 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0017 | 0.0014 | 0.0018 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.034 | 0.4218 | 1 |
Echinococcus granulosus | sex peptide receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0017 | 0.0014 | 0.0018 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Schistosoma mansoni | biogenic amine receptor | 0.0017 | 0.0014 | 0.001 |
Toxoplasma gondii | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase | 0.0062 | 0.0607 | 0.1432 |
Mycobacterium tuberculosis | Hypothetical protein | 0.005 | 0.0446 | 0.0797 |
Echinococcus granulosus | uridine 5' monophosphate synthase | 0.0062 | 0.0607 | 0.0604 |
Brugia malayi | G protein-coupled receptor | 0.0017 | 0.0014 | 0.0018 |
Echinococcus multilocularis | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0042 | 0.0347 | 0.0814 |
Trichomonas vaginalis | esterase, putative | 0.0042 | 0.0347 | 0.2946 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0042 | 0.0347 | 0.0343 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0072 | 0.0734 | 0.13 |
Brugia malayi | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase | 0.004 | 0.0314 | 0.0559 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0105 | 0.1168 | 0.1165 |
Brugia malayi | GnHR receptor homolog | 0.0017 | 0.0014 | 0.0018 |
Plasmodium vivax | hypothetical protein, conserved | 0.0042 | 0.0347 | 0.0814 |
Brugia malayi | Serotonin receptor | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0042 | 0.0347 | 0.0619 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | myosin xvIII | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | orotate phosphoribosyltransferase | 0.0062 | 0.0607 | 0.1072 |
Echinococcus multilocularis | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.1165 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.1165 |
Echinococcus multilocularis | serotonin receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0042 | 0.0347 | 0.0619 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0028 | 0.0168 | 0.0388 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0042 | 0.0347 | 0.0343 |
Trypanosoma cruzi | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0062 | 0.0607 | 0.1432 |
Brugia malayi | RNA binding protein | 0.0072 | 0.0734 | 0.1316 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Echinococcus multilocularis | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Plasmodium falciparum | orotidine 5'-phosphate decarboxylase | 0.0062 | 0.0607 | 0.1432 |
Loa Loa (eye worm) | thymidylate synthase | 0.0105 | 0.1161 | 0.2071 |
Onchocerca volvulus | 0.0105 | 0.1161 | 0.1609 | |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0734 | 0.073 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | dihydrofolate reductase | 0.0442 | 0.5549 | 0.5547 |
Echinococcus multilocularis | GPCR, family 2 | 0.0018 | 0.003 | 0.0027 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0734 | 0.073 |
Schistosoma mansoni | opsin-like receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | sex peptide receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0105 | 0.1158 | 0.2081 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.21 |
Echinococcus granulosus | neuropeptide s receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | Thioredoxin reductase | 0.0046 | 0.0394 | 0.0703 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0116 | 0.1309 | 0.2354 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0042 | 0.0347 | 0.0619 |
Mycobacterium tuberculosis | Probable reductase | 0.0105 | 0.1158 | 0.2081 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0046 | 0.0394 | 0.039 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.003 | 0.003 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0105 | 0.1158 | 0.2081 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.003 | 0.003 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0017 | 0.0014 | 0.001 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.0347 | 0.2946 |
Brugia malayi | TAR-binding protein | 0.0072 | 0.0734 | 0.1316 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0301 | 0.0519 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.0442 | 0.5549 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0083 | 0.0878 | 0.0875 |
Echinococcus granulosus | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium ulcerans | thymidylate synthase | 0.0105 | 0.1161 | 0.2086 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.003 | 0.0048 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0442 | 0.5549 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.3227 | 0.5806 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Loa Loa (eye worm) | beta-lactamase | 0.0042 | 0.0347 | 0.0601 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0105 | 0.1168 | 0.21 |
Schistosoma mansoni | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0042 | 0.0347 | 0.0619 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.003 | 0.0027 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.034 | 0.4218 | 1 |
Schistosoma mansoni | orotidine 5'-phosphate decarboxylase | 0.0062 | 0.0607 | 0.0604 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0301 | 0.0297 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium leprae | Probable orotidine 5'-phosphate decarboxylase PyrF (OMP decarboxylase) (OMPDCase) (OMPdecase) | 0.0062 | 0.0607 | 0.0501 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.003 | 0.0027 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0042 | 0.0347 | 0.2946 |
Echinococcus granulosus | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
PC50 (functional) | = 4.71 uM | Cytotoxicity against human PANC1 cells assessed as cell viability after 3 hrs by WST-8 cells | ChEMBL. | 23287053 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.