Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | metallo-beta-lactamase superfamily protein | 0.0101 | 0.5 | 0.5 |
Echinococcus granulosus | hydroxyacylglutathione hydrolase | 0.0101 | 0.5 | 0.5 |
Mycobacterium leprae | Beta-lactamase-like protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | hydrolase | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | metallo-beta-lactamase family protein | 0.0101 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0101 | 0.5 | 0.5 | |
Trypanosoma cruzi | metallo-beta-lactamase-like protein, putative | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | beta lactamase-like protein | 0.0101 | 0.5 | 0.5 |
Trypanosoma brucei | hydroxyacylglutathione hydrolase, putative | 0.0101 | 0.5 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Trypanosoma cruzi | glyoxalase II | 0.0101 | 0.5 | 0.5 |
Echinococcus granulosus | metallo beta lactamase domain containing protein | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | metallo-beta-lactamase superfamily protein | 0.0101 | 0.5 | 0.5 |
Toxoplasma gondii | metallo-beta-lactamase domain-containing protein | 0.0101 | 0.5 | 0.5 |
Onchocerca volvulus | Putative hydrolase PNKD | 0.0101 | 0.5 | 0.5 |
Echinococcus multilocularis | metallo beta lactamase domain containing protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium leprae | POSSIBLE HYDROLASE | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0101 | 0.5 | 0.5 |
Trypanosoma brucei | glyoxalase II | 0.0101 | 0.5 | 0.5 |
Trypanosoma cruzi | glyoxalase II | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Trypanosoma cruzi | metallo-beta-lactamase superfamily, putative | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0101 | 0.5 | 0.5 |
Echinococcus multilocularis | hydroxyacylglutathione hydrolase | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Loa Loa (eye worm) | metallo-beta-lactamase superfamily protein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0101 | 0.5 | 0.5 |
Echinococcus granulosus | metallo beta lactamase domain containing protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Plasmodium vivax | unspecified product | 0.0101 | 0.5 | 0.5 |
Trypanosoma brucei | metallo-beta-lactamase-like protein, putative | 0.0101 | 0.5 | 0.5 |
Brugia malayi | Chain A, Human Glyoxalase Ii With Cacodylate And Acetate Ions Present In The Active Site. | 0.0101 | 0.5 | 0.5 |
Echinococcus granulosus | zinc phosphodiesterase | 0.0101 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Leishmania major | hydroxyacylglutathione hydrolase, putative,glyoxalase II, putative | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0101 | 0.5 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium leprae | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Trypanosoma cruzi | metallo-beta-lactamase-like protein, putative | 0.0101 | 0.5 | 0.5 |
Loa Loa (eye worm) | hydroxyacylglutathione hydrolase cytoplasmic | 0.0101 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Trypanosoma cruzi | glyoxalase II | 0.0101 | 0.5 | 0.5 |
Onchocerca volvulus | Hydroxyacylglutathione hydrolase, mitochondrial homolog | 0.0101 | 0.5 | 0.5 |
Leishmania major | metallo-beta-lactamase family protein-like protein | 0.0101 | 0.5 | 0.5 |
Toxoplasma gondii | hydroxyacylglutathione hydrolase | 0.0101 | 0.5 | 0.5 |
Schistosoma mansoni | zinc phosphodiesterase | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Beta lactamase like protein | 0.0101 | 0.5 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Possible hydrolase | 0.0101 | 0.5 | 0.5 |
Leishmania major | metallo-beta-lactamase family-like protein | 0.0101 | 0.5 | 0.5 |
Schistosoma mansoni | zinc phosphodiesterase | 0.0101 | 0.5 | 0.5 |
Giardia lamblia | Metallo-beta-lactamase superfamily protein | 0.0101 | 0.5 | 0.5 |
Schistosoma mansoni | hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | Zn-dependent glyoxylase | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | apoptosis inducing factor, putative | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | alkyl sulfatase, putative | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | hydrolase | 0.0101 | 0.5 | 0.5 |
Trypanosoma cruzi | hydroxyacylglutathione hydrolase, putative | 0.0101 | 0.5 | 0.5 |
Brugia malayi | metallo-beta-lactamase superfamily protein | 0.0101 | 0.5 | 0.5 |
Brugia malayi | metallo-beta-lactamase superfamily protein | 0.0101 | 0.5 | 0.5 |
Trypanosoma cruzi | hydroxyacylglutathione hydrolase, putative | 0.0101 | 0.5 | 0.5 |
Echinococcus multilocularis | zinc phosphodiesterase | 0.0101 | 0.5 | 0.5 |
Loa Loa (eye worm) | hydroxyacylglutathione hydrolase | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Echinococcus multilocularis | ETHE1 protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Possible hydrolase | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0101 | 0.5 | 0.5 |
Leishmania major | cleavage and polyadenylation specificity factor, putative | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | metallo-beta-lactamase family protein | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | alkyl sulfatase, putative | 0.0101 | 0.5 | 0.5 |
Trypanosoma brucei | cleavage and polyadenylation specificity factor subunit, putative | 0.0101 | 0.5 | 0.5 |
Echinococcus multilocularis | metallo beta lactamase domain containing protein | 0.0101 | 0.5 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | metallo-beta-lactamase superfamily hydrolase | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | metallo-beta-lactamase family protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | glyoxalase II, GloB | 0.0101 | 0.5 | 0.5 |
Brugia malayi | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium leprae | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0101 | 0.5 | 0.5 |
Trypanosoma cruzi | metallo-beta-lactamase superfamily, putative | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | A-type flavoprotein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Echinococcus granulosus | ETHE1 protein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0101 | 0.5 | 0.5 |
Treponema pallidum | ribonuclease Z | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0101 | 0.5 | 0.5 | |
Mycobacterium ulcerans | hydrolase | 0.0101 | 0.5 | 0.5 |
Giardia lamblia | Hydroxyacylglutathione hydrolase | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Plasmodium falciparum | cytosolic glyoxalase II | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0101 | 0.5 | 0.5 |
Giardia lamblia | Hydroxyacylglutathione hydrolase | 0.0101 | 0.5 | 0.5 |
Plasmodium vivax | hydroxyacyl glutathione hydrolase, putative | 0.0101 | 0.5 | 0.5 |
Chlamydia trachomatis | ribonuclease Z | 0.0101 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.