Detailed information for compound 1728637

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 452.509 | Formula: C20H16N6O3S2
  • H donors: 1 H acceptors: 6 LogP: 3.46 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#Cc1cc(ccc1Oc1nn(cc1C)Cc1ccccc1)S(=O)(=O)Nc1ncns1
  • InChi: 1S/C20H16N6O3S2/c1-14-11-26(12-15-5-3-2-4-6-15)24-19(14)29-18-8-7-17(9-16(18)10-21)31(27,28)25-20-22-13-23-30-20/h2-9,11,13H,12H2,1H3,(H,22,23,25)
  • InChiKey: HHELZPTVPHEAJA-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens sodium channel, voltage-gated, type IX, alpha subunit Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit Get druggable targets OG5_126819 All targets in OG5_126819
Leishmania mexicana calcium channel protein, putative,ion transporter, putative Get druggable targets OG5_126819 All targets in OG5_126819
Leishmania infantum calcium channel protein, putative,ion transporter, putative Get druggable targets OG5_126819 All targets in OG5_126819
Leishmania major calcium channel protein, putative,ion transporter, putative Get druggable targets OG5_126819 All targets in OG5_126819
Echinococcus multilocularis sodium channel protein Get druggable targets OG5_126819 All targets in OG5_126819
Leishmania braziliensis calcium channel protein, putative,ion transporter, putative Get druggable targets OG5_126819 All targets in OG5_126819
Echinococcus granulosus sodium channel protein Get druggable targets OG5_126819 All targets in OG5_126819
Leishmania donovani calcium channel protein, putative Get druggable targets OG5_126819 All targets in OG5_126819

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Schistosoma mansoni neuropeptide F-like receptor 0.0131 0.1231 0.1331
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0044 0.0312 0.051
Loa Loa (eye worm) hypothetical protein 0.0428 0.4363 0.7769
Schistosoma mansoni lipoxygenase 0.0174 0.1681 0.182
Loa Loa (eye worm) hypothetical protein 0.0375 0.38 0.6766
Schistosoma mansoni glutamate receptor kainate 0.0163 0.1562 0.1691
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0268 0.2669 0.5119
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0143 0.1359 0.5005
Schistosoma mansoni amine GPCR 0.0131 0.1231 0.1331
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0224 0.0218
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0036 0.0224 0.0236
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0036 0.0224 0.0367
Echinococcus granulosus adenylate cyclase 9 0.0078 0.0672 0.0666
Echinococcus granulosus glutamate receptor NMDA 0.0079 0.0682 0.0676
Trypanosoma cruzi histone deacetylase, putative 0.0508 0.5201 0.6735
Schistosoma mansoni ATP-binding cassette transporter 0.0163 0.1565 0.1694
Echinococcus multilocularis histone deacetylase 0.0508 0.5201 0.5197
Echinococcus granulosus histone deacetylase 8 0.0133 0.1248 0.1242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0226 0.0768
Brugia malayi intermediate filament protein 0.0027 0.0133 0.0217
Trypanosoma cruzi histone deacetylase 1, putative 0.0291 0.2911 0.3766
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.026 0.0275
Echinococcus multilocularis neuropeptide receptor 0.0131 0.1231 0.1225
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0143 0.1359 0.3505
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.1231 0.1225
Loa Loa (eye worm) hypothetical protein 0.0071 0.0596 0.1062
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0041 0.0282 0.0299
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0061 0.01
Schistosoma mansoni biogenic amine (5HT) receptor 0.0887 0.9203 1
Echinococcus multilocularis potassium voltage gated channel protein 0.0036 0.0224 0.0218
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0071 0.0596 0.1899
Brugia malayi Protein kinase domain containing protein 0.0049 0.0363 0.0595
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0104 0.0354
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0071 0.0596 0.2097
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0061 0.0109
Brugia malayi SRC-1 0.0039 0.0255 0.0417
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0036 0.0225 0.0368
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0071 0.0596 0.1237
Schistosoma mansoni biogenic amine receptor 0.0131 0.1231 0.1331
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0061 0.01
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0046 0.004
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0131 0.1231 0.1225
Echinococcus multilocularis histone deacetylase 3 0.0291 0.2911 0.2906
Loa Loa (eye worm) hypothetical protein 0.0083 0.0728 0.1295
Onchocerca volvulus 0.0042 0.0291 0.098
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0082 0.0712 0.2539
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0061 0.01
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0109
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0399
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0261 0.0853
Echinococcus granulosus biogenic amine 5HT receptor 0.0887 0.9203 0.9202
Plasmodium falciparum DNA gyrase subunit A 0.003 0.0166 0.0291
Trichomonas vaginalis apoptosis inducing factor, putative 0.0071 0.0596 0.2027
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.2942 1
Brugia malayi bZIP transcription factor family protein 0.0084 0.0737 0.1206
Schistosoma mansoni chromobox protein 0.007 0.0585 0.0629
Mycobacterium ulcerans DNA gyrase subunit A 0.003 0.0166 0.0454
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0037 0.0126
Echinococcus granulosus neuropeptide s receptor 0.0593 0.6103 0.61
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0268 0.2669 0.4374
Onchocerca volvulus 0.0083 0.0728 0.2842
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0596 0.0764
Echinococcus granulosus receptor type guanylyl cyclase 0.0028 0.0144 0.0137
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0747 0.7719 1
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0211 0.0378
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0072 0.0085
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0095 0.0155
Giardia lamblia DNA topoisomerase II 0.0133 0.125 0.4157
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0023 0.0089 0.0157
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0037 0.0126
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0039 0.0255 0.0248
Onchocerca volvulus 0.0131 0.1231 0.4988
Echinococcus granulosus tumor protein p63 0.0339 0.3425 0.3421
Schistosoma mansoni disulfide oxidoreductase 0.0071 0.0596 0.0641
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0641 0.6608 0.856
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0071 0.0596 0.1122
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0036 0.0224 0.0218
Echinococcus granulosus glutamate receptor 2 0.0116 0.107 0.1064
Loa Loa (eye worm) TK/EGFR protein kinase 0.0151 0.1438 0.256
Leishmania major histone deacetylase, putative 0.0291 0.2911 0.3766
Brugia malayi G protein-coupled receptor 0.0131 0.1231 0.2017
Mycobacterium tuberculosis Probable dehydrogenase 0.0175 0.1692 0.3566
Echinococcus granulosus tyrosine protein kinase Fyn 0.0039 0.0255 0.0248
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0224 0.0218
Onchocerca volvulus 0.0131 0.1231 0.4988
Loa Loa (eye worm) RGC/RGC protein kinase 0.0028 0.0144 0.0256
Onchocerca volvulus 0.0029 0.0151 0.0386
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0061 0.0054
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0041 0.0282 0.0299
Plasmodium falciparum DNA gyrase subunit B 0.0082 0.071 0.1342
Echinococcus granulosus 7tm_1 domain containing protein 0.0131 0.1231 0.1225
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0268 0.2669 0.5643
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0034 0.0211 0.0204
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0071 0.0596 0.2097
Echinococcus granulosus Polycystic kidney disease protein 0.004 0.0265 0.0258
Schistosoma mansoni glutamate receptor kainate 0.0163 0.1562 0.1691
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0131 0.1231 0.2192
Schistosoma mansoni tyrosine kinase 0.008 0.0687 0.0739
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0036 0.0224 0.0367
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0399
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0131 0.1231 0.1331
Toxoplasma gondii hypothetical protein 0.0036 0.0224 0.0404
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0131 0.1231 0.2192
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0651 0.6712 0.6709
Trypanosoma cruzi trypanothione reductase, putative 0.0268 0.2669 0.3452
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0399
Chlamydia trachomatis DNA gyrase subunit B 0.0065 0.0529 0.1687
Schistosoma mansoni voltage-gated cation channel 0.013 0.1216 0.1315
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0036 0.0224 0.0404
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0109
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0041 0.0276 0.0938
Echinococcus granulosus peptide allatostatin:somatostatin 0.0131 0.1231 0.1225
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0039 0.0255 0.0248
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0131 0.1231 0.2017
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0046 0.0068
Echinococcus granulosus microtubule associated protein 2 0.0693 0.7155 0.7153
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0041 0.0276 0.0491
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0291 0.2911 0.9894
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0323 0.0575
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0046 0.0051
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.1231 0.1225
Brugia malayi Transient-receptor-potential like protein 0.0036 0.0224 0.0367
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0131 0.1231 0.2192
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0005 0.0017
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0034 0.0208 0.0261
Brugia malayi Tachykinin-like peptides receptor 99D 0.0131 0.1231 0.2017
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0082 0.0712 0.2539
Loa Loa (eye worm) neuropeptide F receptor 0.0131 0.1231 0.2192
Brugia malayi ion channel NompC 0.0036 0.0224 0.0367
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0015 0.0008
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0036 0.0224 0.0218
Onchocerca volvulus 0.0239 0.2365 0.9817
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0399
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0095 0.0171
Trichomonas vaginalis histone deacetylase, putative 0.0291 0.2911 0.9894
Onchocerca volvulus 0.0028 0.0144 0.0354
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0131 0.1231 0.1331
Entamoeba histolytica calmodulin, putative 0.0025 0.0107 0.0208
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0023 0.0089 0.0082
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0071 0.0596 0.1122
Echinococcus granulosus hyperpolarization activated cyclic 0.0041 0.0276 0.0269
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.2942 1
Trypanosoma brucei histone deacetylase 2 0.0133 0.1248 0.161
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0157
Echinococcus multilocularis neuropeptide receptor 0.0131 0.1231 0.1225
Schistosoma mansoni histone deacetylase 0.0291 0.2911 0.3158
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.1642 0.558
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0041 0.0282 0.0462
Trypanosoma brucei histone deacetylase 1 0.0291 0.2911 0.3766
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Onchocerca volvulus 0.0131 0.1231 0.4988
Giardia lamblia NADH oxidase lateral transfer candidate 0.0268 0.2669 0.9058
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Echinococcus granulosus voltage gated hydrogen channel 1 0.0036 0.0224 0.0218
Plasmodium falciparum transporter, putative 0.0041 0.0282 0.0515
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0071 0.0596 0.2027
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0156 0.0277
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0036 0.0224 0.0218
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0036 0.0224 0.0367
Echinococcus granulosus hypothetical protein 0.0036 0.0224 0.0218
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0041 0.0282 0.0275
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0046 0.0061
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0015 0.0008
Loa Loa (eye worm) histone deacetylase 7A 0.0508 0.5201 0.9261
Schistosoma mansoni histone deacetylase 1 2 3 0.0133 0.1248 0.135
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0095 0.0185
Echinococcus multilocularis survival motor neuron protein 1 0.0237 0.2351 0.2346
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0046 0.0334 0.1135
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0238 0.081
Echinococcus multilocularis fmrfamide receptor 0.0131 0.1231 0.1225
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.013 0.1216 0.121
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0236
Brugia malayi cation channel family protein 0.0036 0.0224 0.0367
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0387 0.0493
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0399
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0084 0.0737 0.073
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0041 0.0282 0.0299
Echinococcus multilocularis L aminoadipate semialdehyde 0.0083 0.0728 0.0721
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0053 0.0093
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0061 0.0059
Loa Loa (eye worm) hypothetical protein 0.0034 0.0208 0.037
Schistosoma mansoni vesicular amine transporter 0.0036 0.0224 0.0236
Toxoplasma gondii transporter, cation channel family protein 0.0036 0.0224 0.0404
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0015 0.001
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0387 0.038
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0071 0.0596 0.059
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.003 0.0166 0.0454
Plasmodium vivax histone deacetylase, putative 0.0508 0.5201 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0133 0.0236
Brugia malayi jmjC domain containing protein 0.0096 0.0858 0.1406
Plasmodium falciparum LCCL domain-containing protein 0.004 0.0265 0.0483
Brugia malayi Bromodomain containing protein 0.0029 0.0156 0.0255
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0037 0.0126
Brugia malayi nuclear receptor NHR-88 0.002 0.0061 0.01
Echinococcus granulosus tyrosine kinase 0.0025 0.0109 0.0102
Mycobacterium tuberculosis Probable oxidoreductase 0.0372 0.3765 0.7973
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0061 0.01
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0095 0.0155
Echinococcus granulosus tyrosine protein kinase Src42A 0.0039 0.0255 0.0248
Echinococcus granulosus voltage dependent calcium channel 0.0054 0.0412 0.0405
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0007 0.0012
Schistosoma mansoni neuropeptide receptor 0.0131 0.1231 0.1331
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0061 0.0054
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0115 0.1063 0.3874
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0201 0.0684
Schistosoma mansoni polycystin 1-related 0.004 0.0265 0.0281
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0546 0.0699
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0061 0.0109
Echinococcus granulosus histone deacetylase 6 0.0508 0.5201 0.5197
Plasmodium falciparum calmodulin 0.0025 0.0107 0.0177
Brugia malayi Histone deacetylase family protein 0.0508 0.5201 0.8522
Echinococcus granulosus calcium activated potassium channel 0.0036 0.0229 0.0222
Schistosoma mansoni tyrosine kinase 0.0151 0.1438 0.1556
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0014 0.0025
Brugia malayi cation channel family protein 0.0036 0.0224 0.0367
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0061 0.0054
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0131 0.1231 0.1225
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0036 0.0224 0.0236
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Schistosoma mansoni histamine h1 receptor 0.0131 0.1231 0.1331
Echinococcus multilocularis histone deacetylase 6 0.0515 0.5276 0.5273
Trichomonas vaginalis glutathione reductase, putative 0.0268 0.2669 0.9073
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0224 0.0218
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0108
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0041 0.0276 0.0269
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0071 0.0596 0.1122
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.1231 0.1225
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0546 0.0699
Loa Loa (eye worm) hypothetical protein 0.0029 0.0156 0.0277
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0036 0.0224 0.0218
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0036 0.0224 0.0236
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0224 0.0218
Onchocerca volvulus 0.0131 0.1231 0.4988
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0082 0.071 0.1479
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0158 0.1509 0.1947
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0053 0.0059
Echinococcus granulosus glutamate receptor subunit protein glur 0.007 0.058 0.0574
Loa Loa (eye worm) hypothetical protein 0.0019 0.0051 0.009
Echinococcus granulosus FTZ F1 alpha 0.002 0.0061 0.0054
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0036 0.0224 0.0367
Schistosoma mansoni tyrosine kinase 0.008 0.0687 0.0739
Schistosoma mansoni hypothetical protein 0.0131 0.1231 0.1331
Giardia lamblia GTOR 0.0045 0.0323 0.0956
Echinococcus granulosus potassium voltage gated channel protein 0.0036 0.0224 0.0218
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0092 0.0818 0.1051
Brugia malayi AKH receptor 0.0131 0.1231 0.2017
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.0255 0.0248
Chlamydia trachomatis DNA gyrase subunit B 0.0082 0.071 0.2391
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0238 0.03
Brugia malayi Cytochrome P450 family protein 0.0019 0.0053 0.0086
Echinococcus granulosus G protein coupled receptor 139 0.0131 0.1231 0.1225
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0071 0.0596 0.0764
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0186 0.1803 0.1798
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.0596 0.0764
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0291 0.2911 0.9894
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0061 0.01
Loa Loa (eye worm) hypothetical protein 0.0133 0.1248 0.2222
Schistosoma mansoni ap endonuclease 0.0019 0.0046 0.0043
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0131 0.1231 0.1331
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0071 0.0596 0.1122
Echinococcus granulosus calmodulin 0.0025 0.0107 0.01
Echinococcus granulosus glutamate synthase 0.0071 0.0596 0.059
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0041 0.0276 0.0293
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0071 0.0596 0.2027
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0036 0.0224 0.0367
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0131 0.1231 0.1225
Loa Loa (eye worm) histone deacetylase 11 0.0133 0.1248 0.2222
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0236
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.2942 1
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0236
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.1231 0.1331
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0174 0.1681 0.1675
Schistosoma mansoni glutamate receptor AMPA 0.0163 0.1562 0.1691
Schistosoma mansoni lamin 0.0027 0.0133 0.0137
Toxoplasma gondii transporter, cation channel family protein 0.0036 0.0224 0.0404
Loa Loa (eye worm) voltage-dependent calcium channel 0.0054 0.0412 0.0733
Loa Loa (eye worm) hypothetical protein 0.0025 0.0114 0.0203
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0061 0.0109
Echinococcus multilocularis calmodulin 0.0025 0.0107 0.01
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0036 0.0224 0.0218
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0036 0.0224 0.0367
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0015 0.001
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0174 0.1682 0.5717
Leishmania major ferric reductase, putative 0.0034 0.0208 0.0261
Brugia malayi neuropeptide F receptor 0.0131 0.1231 0.2017
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0197 0.0369
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0152 0.0145
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0236
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0071 0.0596 0.1899
Schistosoma mansoni hypothetical protein 0.0131 0.1231 0.1331
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0078 0.0672 0.2606
Brugia malayi G protein-coupled receptor F59B2.13 0.0131 0.1231 0.2017
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0014 0.0007
Trichomonas vaginalis histone deacetylase, putative 0.0291 0.2911 0.9894
Echinococcus granulosus glutamate receptor ionotropic kainate 0.007 0.058 0.0574
Trypanosoma cruzi NADH dehydrogenase, putative 0.0071 0.0596 0.0764
Loa Loa (eye worm) hypothetical protein 0.0376 0.381 0.6785
Schistosoma mansoni lamin 0.0027 0.0133 0.0137
Brugia malayi Dopamine receptor protein 1 0.0547 0.5616 0.9202
Echinococcus multilocularis nmda type glutamate receptor 0.0102 0.0924 0.0918
Brugia malayi Metabotropic glutamate receptor precursor. 0.0023 0.0089 0.0145
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.0255 0.0248
Echinococcus granulosus ryanodine receptor 44f 0.0036 0.0225 0.0218
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0015 0.0008
Echinococcus multilocularis voltage dependent calcium channel 0.013 0.1216 0.121
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0059 0.0467 0.1602
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0133 0.0217
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0041 0.0282 0.0515
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0238 0.081
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0041 0.0282 0.0299
Loa Loa (eye worm) G-protein coupled receptor 0.0131 0.1231 0.2192
Schistosoma mansoni hypothetical protein 0.017 0.1642 0.1778
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0071 0.0596 0.059
Onchocerca volvulus 0.0131 0.1231 0.4988
Echinococcus granulosus potassium voltage gated channel protein 0.0036 0.0224 0.0218
Loa Loa (eye worm) hypothetical protein 0.0041 0.0282 0.0502
Brugia malayi neuropeptide F receptor 0.0131 0.1231 0.2017
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0175 0.1692 0.3566
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0036 0.0224 0.0282
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0399
Loa Loa (eye worm) TYRA-2 protein 0.0131 0.1231 0.2192
Brugia malayi hypothetical protein 0.0131 0.1231 0.2017
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0061 0.0109
Leishmania major C-8 sterol isomerase-like protein 0.037 0.3746 0.4849
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0082 0.071 0.2531
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0071 0.0596 0.1237
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0071 0.0596 0.0977
Leishmania major calmodulin, putative 0.0025 0.0107 0.0129
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0034 0.0208 0.0261
Schistosoma mansoni protein kinase 0.0028 0.0144 0.0149
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0747 0.7719 1
Echinococcus granulosus histone deacetylase 7 0.0508 0.5201 0.5197
Leishmania major hypothetical protein, conserved 0.0071 0.0596 0.0764
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0268 0.2669 0.5119
Loa Loa (eye worm) hypothetical protein 0.0243 0.2408 0.4287
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0387 0.1315
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0387 0.0493
Echinococcus multilocularis sodium channel protein 0.0474 0.4842 0.4839
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0041 0.0282 0.0502
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0061 0.0054
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0037 0.0126
Echinococcus multilocularis potassium voltage gated channel protein 0.0036 0.0224 0.0218
Echinococcus multilocularis voltage gated potassium channel 0.0036 0.0224 0.0218
Brugia malayi glutathione reductase 0.0462 0.4719 0.7733
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0023 0.0089 0.0157
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0034 0.0208 0.0261
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0061 0.0054
Brugia malayi Glutamate receptor 2 precursor 0.0163 0.1562 0.2559
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0546 0.0587
Loa Loa (eye worm) hypothetical protein 0.0036 0.0227 0.0404
Loa Loa (eye worm) hypothetical protein 0.013 0.1216 0.2165
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0265 0.0258
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0261 0.0887
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0157
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0061 0.01
Plasmodium falciparum thioredoxin reductase 0.0268 0.2669 0.5119
Schistosoma mansoni opsin-like receptor 0.0131 0.1231 0.1331
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0399
Loa Loa (eye worm) hypothetical protein 0.0077 0.0659 0.1173
Loa Loa (eye worm) hypothetical protein 0.0041 0.0282 0.0502
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.014 0.0476
Schistosoma mansoni tyrosine kinase 0.0025 0.0109 0.0111
Loa Loa (eye worm) hypothetical protein 0.0039 0.0256 0.0455
Trypanosoma cruzi histone deacetylase, putative 0.0133 0.1248 0.161
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0131 0.1231 0.1331
Echinococcus granulosus g-protein coupled receptor 0.0131 0.1231 0.1225
Schistosoma mansoni glutamate synthase 0.0071 0.0596 0.0641
Echinococcus multilocularis calmodulin 0.0025 0.0106 0.01
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0071 0.0596 0.1122
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.014 0.1327 0.2175
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0037 0.0126
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.1231 0.1225
Schistosoma mansoni glutamate synthase 0.0071 0.0596 0.0641
Echinococcus multilocularis neuropeptide Y receptor 0.0131 0.1231 0.1225
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0277 0.027
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0399
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0071 0.0596 0.0764
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0156 0.0149
Toxoplasma gondii hypothetical protein 0.0041 0.0282 0.0515
Trypanosoma brucei DNA topoisomerase ii 0.0158 0.1509 0.1947
Schistosoma mansoni hypothetical protein 0.0016 0.0014 0.0008
Brugia malayi Inositol-1 0.0037 0.0238 0.039
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0071 0.0596 0.1446
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0071 0.0596 0.2027
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0312 0.0332
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0061 0.01
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0036 0.0224 0.0236
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0226 0.0768
Echinococcus multilocularis sodium and chloride dependent glycine 0.0041 0.0282 0.0275
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0071 0.0596 0.059
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0036 0.0224 0.0218
Brugia malayi Probable DNA topoisomerase II 0.014 0.1327 0.2175
Onchocerca volvulus Alhambra homolog 0.0029 0.0156 0.0406
Toxoplasma gondii NADPH-glutathione reductase 0.0268 0.2669 0.5119
Toxoplasma gondii calmodulin, putative 0.0025 0.0107 0.0177
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0131 0.1231 0.1225
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.1642 0.558
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0157
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Loa Loa (eye worm) thioredoxin reductase 0.0462 0.4719 0.8403
Brugia malayi sulfakinin receptor protein 0.0131 0.1231 0.2017
Onchocerca volvulus 0.002 0.0061 0.0003
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0071 0.0596 0.059
Loa Loa (eye worm) hypothetical protein 0.037 0.3746 0.6671
Onchocerca volvulus 0.0131 0.1231 0.4988
Brugia malayi Guanylyl cyclase protein 23 0.0028 0.0144 0.0235
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0387 0.0688
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.2942 1
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0036 0.0224 0.0218
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0428 0.4363 0.4737
Onchocerca volvulus 0.0048 0.0358 0.1267
Trypanosoma cruzi trypanothione reductase, putative 0.0462 0.4719 0.611
Brugia malayi chromobox protein homolog 3 0.0039 0.0261 0.0427
Schistosoma mansoni transient receptor potential channel 0.0036 0.0224 0.0236
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.013 0.1216 0.121
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0371 0.0396
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0046 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0007 0.0023
Schistosoma mansoni neuropeptide f receptor 76f 0.0131 0.1231 0.1331
Loa Loa (eye worm) hypothetical protein 0.005 0.0375 0.0668
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0131 0.1231 0.1331
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0236
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0041 0.0276 0.0293
Echinococcus granulosus tm gpcr rhodopsin 0.0131 0.1231 0.1225
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0747 0.7719 1
Trypanosoma brucei cytochrome P450, putative 0.0019 0.0053 0.0059
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0071 0.0596 0.059
Onchocerca volvulus Glucosylceramidase homolog 0.017 0.1642 0.6736
Schistosoma mansoni tyrosine kinase 0.0039 0.0255 0.027
Loa Loa (eye worm) hypothetical protein 0.0041 0.0282 0.0502
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.2582 0.8776
Schistosoma mansoni amine GPCR 0.0131 0.1231 0.1331
Schistosoma mansoni sodium/chloride dependent transporter 0.0243 0.2408 0.2611
Echinococcus granulosus nmda type glutamate receptor 0.0187 0.1816 0.181
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0268 0.2669 1
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0061 0.0055
Leishmania major hypothetical protein, conserved 0.0034 0.0211 0.0264
Echinococcus granulosus potassium voltage gated channel protein 0.0036 0.0224 0.0218
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0641 0.6608 0.856
Echinococcus granulosus short transient receptor potential channel 6 0.0036 0.0227 0.022
Loa Loa (eye worm) hypothetical protein 0.0291 0.2911 0.5183
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0323 0.1098
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0061 0.0054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0201 0.0684
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0082 0.071 0.2293
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0131 0.1231 0.2192
Echinococcus granulosus fmrfamide receptor 0.0131 0.1231 0.1225
Schistosoma mansoni glutamate synthase 0.0071 0.0596 0.0641
Loa Loa (eye worm) TK protein kinase 0.0031 0.0176 0.0313
Echinococcus multilocularis chromobox protein 1 0.007 0.0585 0.0579
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0095 0.0114
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0014 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0201 0.0684
Echinococcus granulosus serotonin transporter 0.0243 0.2408 0.2402
Onchocerca volvulus Neuropeptide F receptor homolog 0.0131 0.1231 0.4988
Brugia malayi calmodulin 0.0025 0.0107 0.0174
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0224 0.0218
Plasmodium falciparum DNA topoisomerase 2 0.014 0.1327 0.2531
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0238 0.0732
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0156 0.0149
Echinococcus granulosus neuropeptides capa receptor 0.0131 0.1231 0.1225
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0036 0.0224 0.0236
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0387 0.0413
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0151 0.0269
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0071 0.0596 0.2027
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0061 0.0054
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0041 0.0282 0.0299
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.017 0.0163
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0082 0.0707 0.0701
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0071 0.0596 0.1062
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0387 0.038
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0175 0.1692 0.3566
Loa Loa (eye worm) hypothetical protein 0.0189 0.184 0.3277
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0133 0.0236
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0238 0.0424
Schistosoma mansoni lipoxygenase 0.0103 0.0929 0.1003
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0061 0.0059
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0071 0.0596 0.0764
Loa Loa (eye worm) voltage-gated potassium channel 0.0036 0.0224 0.0399
Treponema pallidum thioredoxin reductase (trxB) 0.0071 0.0596 0.1899
Loa Loa (eye worm) TK protein kinase 0.0035 0.0216 0.0384
Echinococcus multilocularis g-protein coupled receptor 0.0131 0.1231 0.1225
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0071 0.0596 0.1237
Echinococcus multilocularis short transient receptor potential channel 6 0.0036 0.0224 0.0218
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0015 0.0023
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0131 0.1231 0.1331
Schistosoma mansoni histone deacetylase hda2 0.0133 0.1248 0.135
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0156 0.0273
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0109
Echinococcus granulosus atrial natriuretic peptide receptor 0.0023 0.0089 0.0082
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0277 0.027
Leishmania major hypothetical protein, conserved 0.0071 0.0596 0.0764
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0077 0.0659 0.137
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Echinococcus multilocularis neuropeptide FF receptor 2 0.0131 0.1231 0.1225
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0041 0.0276 0.0269
Brugia malayi hypothetical protein 0.0131 0.1231 0.2017
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0077 0.0659 0.1615
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0131 0.1231 0.2017
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0238 0.0252
Loa Loa (eye worm) hypothetical protein 0.005 0.0371 0.066
Giardia lamblia Thioredoxin reductase 0.0071 0.0596 0.1899
Schistosoma mansoni hypothetical protein 0.004 0.0265 0.0281
Entamoeba histolytica thioredoxin reductase, putative 0.0071 0.0596 0.1899
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0036 0.0224 0.0282
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.0201 0.036
Echinococcus multilocularis transfer RNA-Gly 0.0036 0.0224 0.0218
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0226 0.0768
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.013 0.1216 0.121
Plasmodium vivax histone deacetylase, putative 0.0133 0.1248 0.2379
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0036 0.0224 0.0218
Toxoplasma gondii DNA topoisomerase 2, putative 0.014 0.1327 0.2531
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0114 0.0139
Schistosoma mansoni ap endonuclease 0.0019 0.0046 0.0043
Trypanosoma cruzi calmodulin 0.0025 0.0107 0.0129
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0282 0.0515
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0131 0.1231 0.1331
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0143 0.1359 0.2858
Schistosoma mansoni tyrosine kinase 0.0049 0.0363 0.0387
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0049 0.0363 0.0356
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0211 0.0264
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.014 0.1327 0.1321
Treponema pallidum fructose-bisphosphate aldolase 0.0294 0.2942 1
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0015 0.0008
Onchocerca volvulus 0.0131 0.1231 0.4988
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0061 0.0054
Schistosoma mansoni hypothetical protein 0.0048 0.0358 0.0382
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0131 0.1231 0.1225
Plasmodium vivax SET domain protein, putative 0.0031 0.017 0.03
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0036 0.0224 0.0367
Loa Loa (eye worm) hypothetical protein 0.004 0.0265 0.0471
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0033 0.0198 0.0576
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0375 0.0614
Echinococcus granulosus short transient receptor potential channel 6 0.0036 0.0224 0.0218
Mycobacterium ulcerans NADH dehydrogenase 0.0071 0.0596 0.2097
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0061 0.01
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0041 0.0276 0.0938
Schistosoma mansoni hypothetical protein 0.0069 0.057 0.0612
Echinococcus granulosus shaker cognate 0.0036 0.0224 0.0218
Brugia malayi larval opioid receptor 0.0131 0.1231 0.2017
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0095 0.0848 0.3352
Schistosoma mansoni voltage-gated ion channel 0.0036 0.0224 0.0236
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0399
Echinococcus multilocularis serotonin receptor 0.0376 0.381 0.3806
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0095 0.0155
Trypanosoma brucei C-8 sterol isomerase, putative 0.037 0.3746 0.4849
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0046 0.0158
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0046 0.0051
Echinococcus multilocularis sex peptide receptor 0.0131 0.1231 0.1225
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.1231 0.1331
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0071 0.0596 0.2027
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0546 0.054
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0036 0.0224 0.0367
Echinococcus granulosus calmodulin 0.0025 0.0106 0.01
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0131 0.1231 0.1225
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0077 0.0659 0.1242
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0238 0.081
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0023 0.0089 0.0082
Schistosoma mansoni survival motor neuron protein 0.0048 0.0358 0.0382
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.0255 0.0248
Schistosoma mansoni adenoreceptor 0.0131 0.1231 0.1331
Brugia malayi MAP kinase sur-1 0.0051 0.0387 0.0633
Loa Loa (eye worm) hypothetical protein 0.0057 0.0449 0.08
Echinococcus multilocularis tyrosine protein kinase Srms 0.0035 0.0216 0.0209
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0038 0.0248 0.0696
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0186 0.1803 0.1798
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Trypanosoma cruzi target of rapamycin kinase 3 0.0036 0.0226 0.0284
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0071 0.0596 0.1446
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0157
Plasmodium falciparum thioredoxin reductase 0.0462 0.4719 0.9071
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0131 0.1231 0.2192
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0268 0.2669 1
Schistosoma mansoni cpg binding protein 0.003 0.0169 0.0176
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0268 0.2669 1
Schistosoma mansoni transient receptor potential channel 0.0036 0.0227 0.0239
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0236
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0038 0.0248 0.0768
Schistosoma mansoni hypothetical protein 0.017 0.1642 0.1778
Onchocerca volvulus 0.0131 0.1231 0.4988
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0095 0.0848 0.3352
Loa Loa (eye worm) glutamate receptor 0.0023 0.0089 0.0157
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0265 0.0258
Schistosoma mansoni hypothetical protein 0.007 0.058 0.0624
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0036 0.0224 0.0367
Loa Loa (eye worm) histone deacetylase 1 0.0291 0.2911 0.5183
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.013 0.1216 0.121
Giardia lamblia Glutamate synthase 0.0071 0.0596 0.1899
Chlamydia trachomatis endonuclease IV 0.0077 0.0659 0.2191
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0007 0.0011
Brugia malayi ORL1-like opioid receptor 0.0131 0.1231 0.2017
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0131 0.1231 0.1331
Onchocerca volvulus 0.0131 0.1231 0.4988
Brugia malayi steroid hormone receptor 0.002 0.0061 0.01
Echinococcus granulosus chromobox protein 1 0.007 0.0585 0.0579
Brugia malayi isocitrate dehydrogenase 0.0016 0.0015 0.0023
Loa Loa (eye worm) hypothetical protein 0.0428 0.4363 0.7769
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0268 0.2669 0.3452
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0387 0.1315
Mycobacterium ulcerans hypothetical protein 0.0028 0.0146 0.0378
Schistosoma mansoni amine GPCR 0.0131 0.1231 0.1331
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0096 0.0858 0.0852
Toxoplasma gondii hypothetical protein 0.0036 0.0224 0.0404
Schistosoma mansoni cpg binding protein 0.0029 0.0151 0.0157
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0071 0.0596 0.2027
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0312 0.0332
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0399
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0104 0.0354
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0375 0.0668
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0061 0.01
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.1642 0.558
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0036 0.0224 0.0236
Plasmodium vivax histone deacetylase 2, putative 0.0508 0.5201 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0028 0.0144 0.0256
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.0323 0.0316
Brugia malayi Dopamine receptor 0.0131 0.1231 0.2017
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0036 0.0224 0.0218
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0038 0.0248 0.0594
Leishmania major extracellular receptor, putative 0.0023 0.0089 0.0106
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0174 0.1681 0.1675
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0046 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0201 0.0684
Loa Loa (eye worm) melatonin receptor type 1A 0.0131 0.1231 0.2192
Echinococcus multilocularis sodium and chloride dependent glycine 0.0041 0.0282 0.0275
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0109
Echinococcus granulosus voltage gated potassium channel 0.0044 0.0312 0.0305
Trypanosoma cruzi NADH dehydrogenase, putative 0.0071 0.0596 0.0764
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0041 0.0282 0.0275
Schistosoma mansoni histone deacetylase 0.0291 0.2911 0.3158
Onchocerca volvulus Dual oxidase homolog 0.0073 0.0617 0.2369
Loa Loa (eye worm) calcium channel 0.013 0.1216 0.2165
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0041 0.0276 0.0269
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0259 0.2582 0.4231
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.0323 0.041
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0186 0.1803 0.1798
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0211 0.0378
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0033 0.0198 0.0576
Echinococcus granulosus neuropeptides capa receptor 0.0131 0.1231 0.1225
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.1642 0.558
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0071 0.0596 0.059
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.007 0.058 0.0574
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0641 0.6608 0.856
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0071 0.0596 0.0764
Onchocerca volvulus 0.005 0.0371 0.1322
Schistosoma mansoni neuropeptide F-like receptor 0.0131 0.1231 0.1331
Echinococcus granulosus histone deacetylase 6 0.0515 0.5276 0.5273
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0033 0.0196 0.0189
Plasmodium falciparum histone deacetylase 1 0.0291 0.2911 0.5585
Schistosoma mansoni histone deacetylase 4 5 0.0508 0.5201 0.5648
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0061 0.0054
Trypanosoma brucei histone deacetylase, putative 0.0508 0.5201 0.6735
Loa Loa (eye worm) hypothetical protein 0.0019 0.0051 0.009
Onchocerca volvulus 0.0041 0.0282 0.0942
Plasmodium vivax DNA gyrase subunit B, putative 0.0082 0.071 0.1342
Schistosoma mansoni hypothetical protein 0.0071 0.0596 0.0641
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0071 0.0596 0.059
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0036 0.0224 0.0236
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0294 0.2942 1
Brugia malayi metabotropic glutamate receptor type 2 0.0023 0.0089 0.0145
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.003 0.0166 0.0291
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0071 0.0596 0.2097
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0292 0.0986
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0641 0.6608 0.856
Schistosoma mansoni voltage-dependent calcium channel 0.0036 0.0224 0.0236
Mycobacterium ulcerans ferredoxin reductase 0.0071 0.0596 0.2097
Brugia malayi putative neuropeptide receptor 0.0131 0.1231 0.2017
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0039 0.0255 0.0248
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.2582 0.8776
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0041 0.0276 0.0269
Brugia malayi hypothetical protein 0.0131 0.1231 0.2017
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0571 0.5865 0.7596
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.021 0.2058 0.3664
Echinococcus multilocularis potassium large conductance calcium activated 0.0036 0.0224 0.0218
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0571 0.5865 0.7596
Trypanosoma cruzi calmodulin, putative 0.0025 0.0107 0.0129
Echinococcus granulosus histone deacetylase 3 0.0291 0.2911 0.2906
Echinococcus multilocularis voltage gated potassium channel 0.0044 0.0312 0.0305
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0157
Toxoplasma gondii hypothetical protein 0.0018 0.0035 0.0039
Echinococcus multilocularis peregrin 0.0029 0.0156 0.0149
Echinococcus multilocularis thioredoxin glutathione reductase 0.0462 0.4719 0.4715
Loa Loa (eye worm) hypothetical protein 0.0082 0.0712 0.1268
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0217 0.2134 0.8833
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0399
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0025
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0053 0.0059
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0268 0.2669 0.5119
Brugia malayi olfactory channel protein osm-9 0.0036 0.0227 0.0371
Brugia malayi Cytochrome P450 family protein 0.0019 0.0053 0.0086
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0041 0.0282 0.0275
Plasmodium vivax histone deacetylase 1, putative 0.0291 0.2911 0.5585
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0131 0.1231 0.2017
Schistosoma mansoni hypothetical protein 0.0131 0.1231 0.1331
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0104 0.0353
Echinococcus granulosus potassium voltage gated channel subfamily H 0.007 0.0589 0.0583
Echinococcus granulosus lamin 0.0027 0.0133 0.0126
Trypanosoma cruzi calmodulin 0.0025 0.0107 0.0129
Brugia malayi Serotonin receptor 0.0593 0.6103 1
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0238 0.0663
Echinococcus multilocularis serotonin receptor 0.0376 0.381 0.3806
Echinococcus granulosus tyrosine protein kinase Blk 0.0035 0.0216 0.0209
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0036 0.0224 0.0404
Echinococcus granulosus sodium leak channel non selective protein 0.0036 0.0224 0.0218
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0037 0.0126
Leishmania major DNA topoisomerase ii 0.0133 0.1248 0.1609
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0259 0.2582 0.4598
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0023 0.0089 0.0157
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0071 0.0596 0.2097
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0071 0.0596 0.0977
Onchocerca volvulus 0.004 0.0265 0.087
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.0323 0.0344
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0474 0.4842 0.4839
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0157
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0323 0.1098
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0375 0.0614
Echinococcus granulosus sodium channel protein 0.0435 0.4436 0.4432
Echinococcus granulosus glutamate receptor 2 0.0186 0.1803 0.1798
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0061 0.0059
Brugia malayi Glutamate receptor 1 precursor 0.0163 0.1562 0.2559
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.1231 0.1225
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0372 0.3765 0.7973
Treponema pallidum hypothetical protein 0.0028 0.0146 0.0342
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0109
Loa Loa (eye worm) neuropeptide F receptor 0.0131 0.1231 0.2192
Schistosoma mansoni ryanodine receptor related 0.0036 0.0225 0.0237
Echinococcus multilocularis g protein coupled receptor 0.0131 0.1231 0.1225
Schistosoma mansoni myosin xvIII 0.0131 0.1231 0.1331
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0071 0.0596 0.0764
Loa Loa (eye worm) hypothetical protein 0.0054 0.0412 0.0733
Schistosoma mansoni glutamate receptor AMPA 0.0163 0.1562 0.1691
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0131 0.1231 0.1225
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0174 0.1682 0.5717
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0071 0.0596 0.2027
Loa Loa (eye worm) doublecortin family protein 0.004 0.0265 0.0471
Echinococcus multilocularis nmda type glutamate receptor 0.0187 0.1816 0.181
Echinococcus granulosus hyperpolarization activated cyclic 0.0041 0.0276 0.0269
Brugia malayi RE15519p 0.0131 0.1231 0.2017
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0071 0.0596 0.0764
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0211 0.0264
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0071 0.0596 0.2097
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0071 0.0596 0.1899
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0061 0.0098
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.2582 0.8776
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0071 0.0596 0.059
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0052 0.0391 0.1314
Schistosoma mansoni tyrosine kinase 0.0039 0.0255 0.027
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.017 0.0177
Mycobacterium ulcerans glutamate synthase subunit beta 0.0071 0.0596 0.2097
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0186 0.1803 0.1798
Schistosoma mansoni transient receptor potential channel 4 0.0036 0.0224 0.0236
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0129 0.0438
Schistosoma mansoni amine GPCR 0.0131 0.1231 0.1331
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0252 0.0245
Schistosoma mansoni opsin-like receptor 0.0131 0.1231 0.1331
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0261 0.0887
Trichomonas vaginalis glutamate synthase, putative 0.0071 0.0596 0.2027
Schistosoma mansoni jumonji domain containing protein 0.0076 0.0651 0.07
Leishmania major histone deacetylase, putative 0.0291 0.2911 0.3766
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0014 0.0023
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0041 0.0282 0.0726
Brugia malayi Thioredoxin reductase 0.0462 0.4719 0.7733
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0036 0.0224 0.0218
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0041 0.0276 0.0491
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0015 0.001
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0038 0.0248 0.0696
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0039 0.0255 0.0248
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0268 0.2669 0.2664
Loa Loa (eye worm) serotonin transporter b 0.0243 0.2408 0.4287
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0236
Schistosoma mansoni cpg binding protein 0.003 0.0169 0.0176
Echinococcus multilocularis sodium leak channel non selective protein 0.0036 0.0224 0.0218
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0071 0.0596 0.1899
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0268 0.2669 0.3452
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0131 0.1231 0.1225
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0387 0.1176
Loa Loa (eye worm) TOPoisomerase family member 0.014 0.1327 0.2363
Schistosoma mansoni hypothetical protein 0.0016 0.0014 0.0008
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0571 0.5865 0.7596
Loa Loa (eye worm) hypothetical protein 0.0041 0.0282 0.0502
Schistosoma mansoni hypothetical protein 0.0029 0.0156 0.0162
Trichomonas vaginalis chromobox protein, putative 0.007 0.0585 0.1989
Echinococcus multilocularis CalModulin family member (cmd 1) 0.0025 0.0107 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0104 0.0354
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0061 0.0059
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0061 0.0003
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0036 0.0224 0.0236
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0071 0.0596 0.2097
Echinococcus granulosus sodium and chloride dependent glycine 0.0041 0.0282 0.0275
Schistosoma mansoni amine GPCR 0.063 0.6493 0.7053
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0208 0.0341
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0221 0.0214
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0014 0.0007
Trypanosoma cruzi extracellular receptor, putative 0.0023 0.0089 0.0106
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0007 0.0023
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0036 0.0224 0.0218
Loa Loa (eye worm) TK/INSR protein kinase 0.0049 0.0363 0.0646
Onchocerca volvulus 0.0041 0.0282 0.0942
Schistosoma mansoni alpha-1 adrenergic receptor 0.0131 0.1231 0.1331
Echinococcus granulosus RUN 0.004 0.0265 0.0258
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0071 0.0596 0.0764
Trypanosoma brucei protein kinase, putative 0.0051 0.0387 0.0493
Trichomonas vaginalis histone deacetylase, putative 0.0291 0.2911 0.9894
Brugia malayi CXXC zinc finger family protein 0.0029 0.0151 0.0248
Brugia malayi hypothetical protein 0.0131 0.1231 0.2017
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0041 0.0282 0.0275
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0292 0.0993
Echinococcus granulosus g protein coupled receptor 0.0131 0.1231 0.1225
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0071 0.0596 0.0764
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Echinococcus granulosus jun protein 0.0084 0.0737 0.073
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0061 0.01
Echinococcus multilocularis lamin 0.0027 0.0133 0.0126
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0156 0.0162
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0156 0.0531
Brugia malayi hypothetical protein 0.0131 0.1231 0.2017
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0167 0.0566
Schistosoma mansoni neuropeptide receptor 0.0131 0.1231 0.1331
Leishmania major hypothetical protein, unknown function 0.0036 0.0224 0.0282
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0071 0.0596 0.2097
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0399
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0747 0.7719 1
Echinococcus multilocularis RUN 0.004 0.0265 0.0258
Echinococcus multilocularis tyrosine protein kinase Blk 0.0035 0.0216 0.0209
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0114 0.0139
Echinococcus granulosus 7TM GPCR rhodopsin 0.0131 0.1231 0.1225
Echinococcus granulosus neuropeptide receptor 0.0131 0.1231 0.1225
Echinococcus granulosus histone deacetylase 0.0508 0.5201 0.5197
Toxoplasma gondii histone deacetylase HDAC3 0.0291 0.2911 0.5585
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.1231 0.1225
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0238 0.0432
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0546 0.0972
Echinococcus multilocularis tyrosine protein kinase HCK 0.0031 0.0176 0.0169
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Echinococcus granulosus thioredoxin glutathione reductase 0.0462 0.4719 0.4715
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0046 0.0158
Brugia malayi hypothetical protein 0.0023 0.0089 0.0145
Echinococcus granulosus calmodulin 0.0025 0.0107 0.01
Echinococcus multilocularis histone deacetylase 6 0.0508 0.5201 0.5197
Brugia malayi histone deacetylase 1 (HD1) 0.0291 0.2911 0.477
Brugia malayi Melatonin receptor type 1A 0.0131 0.1231 0.2017
Schistosoma mansoni inositol monophosphatase 0.0037 0.0238 0.0252
Loa Loa (eye worm) hypothetical protein 0.0547 0.5616 1
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0071 0.0596 0.059
Brugia malayi Histone deacetylase family protein 0.0508 0.5201 0.8522
Echinococcus multilocularis two pore calcium channel protein 2 0.0036 0.0224 0.0218
Echinococcus granulosus neuropeptide Y receptor 0.0131 0.1231 0.1225
Onchocerca volvulus 0.0041 0.0282 0.0942
Onchocerca volvulus 0.0027 0.0133 0.0307
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0201 0.0684
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0071 0.0596 0.0764
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.2942 1
Echinococcus multilocularis glutamate receptor 2 0.0186 0.1803 0.1798
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0036 0.0232 0.0462
Mycobacterium ulcerans DNA gyrase subunit B 0.0082 0.071 0.2531
Plasmodium falciparum amino acid transporter, putative 0.0041 0.0282 0.0515
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0387 0.0493
Loa Loa (eye worm) SRC-1 0.0039 0.0255 0.0453
Echinococcus granulosus tyrosine protein kinase HCK 0.0031 0.0176 0.0169
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.003 0.0166 0.0412
Loa Loa (eye worm) hypothetical protein 0.0019 0.0051 0.009
Echinococcus granulosus neuropeptide receptor A26 0.0593 0.6103 0.61
Schistosoma mansoni sodium/chloride dependent transporter 0.0041 0.0282 0.0299
Schistosoma mansoni rab6-interacting 0.004 0.0265 0.0281
Schistosoma mansoni hypothetical protein 0.0036 0.0224 0.0236
Echinococcus granulosus tm gpcr rhodopsin 0.0651 0.6712 0.6709
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0109
Loa Loa (eye worm) hypothetical protein 0.0547 0.5616 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0007 0.0023
Echinococcus multilocularis conserved hypothetical protein 0.0036 0.0224 0.0218
Mycobacterium ulcerans hypothetical protein 0.0071 0.0596 0.2097
Schistosoma mansoni sulfide quinone reductase 0.0071 0.0596 0.0641
Echinococcus granulosus metabotropic glutamate receptor 2 0.0023 0.0089 0.0082
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0387 0.0493
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.003 0.0166 0.0321
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.1231 0.1225
Schistosoma mansoni tyrosine kinase 0.0082 0.0707 0.0761
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0372 0.3765 1
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0036 0.0224 0.0218
Echinococcus multilocularis calmodulin 0.0025 0.0107 0.01
Loa Loa (eye worm) blistered cuticle protein 3 0.0073 0.0617 0.1098
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0243 0.2408 0.2611
Echinococcus multilocularis histone deacetylase 1 0.0291 0.2911 0.2906
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.017 0.03
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0096 0.0858 0.0852
Schistosoma mansoni tyrosine kinase 0.008 0.0687 0.0739
Mycobacterium ulcerans endonuclease IV 0.0077 0.0659 0.2335
Brugia malayi GnHR receptor homolog 0.0131 0.1231 0.2017
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0039 0.0255 0.0248
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0061 0.0003
Loa Loa (eye worm) hypothetical protein 0.0041 0.0282 0.0502
Trypanosoma cruzi DNA topoisomerase II, putative 0.0133 0.1248 0.1609
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0546 0.1726
Trypanosoma brucei calmodulin 0.0025 0.0107 0.0129
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0036 0.0224 0.0697
Loa Loa (eye worm) histone deacetylase 3 0.0291 0.2911 0.5183
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0061 0.0054
Brugia malayi nuclear hormone receptor 0.002 0.0061 0.01
Mycobacterium ulcerans dehydrogenase 0.0071 0.0596 0.2097
Schistosoma mansoni calcium-activated potassium channel 0.0036 0.0224 0.0236
Plasmodium vivax DNA gyrase subunit A, putative 0.003 0.0166 0.0291
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0039 0.0255 0.0248
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0114 0.0192
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0095 0.0114
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0156 0.0273
Echinococcus multilocularis serotonin transporter 0.0243 0.2408 0.2402
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0186 0.1803 0.1798
Schistosoma mansoni metabotropic glutamate receptor 0.0023 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0039 0.0261 0.0464
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0015 0.0026
Onchocerca volvulus 0.0075 0.0637 0.2457
Loa Loa (eye worm) hypothetical protein 0.0031 0.0172 0.0305
Echinococcus granulosus calmodulin 0.0025 0.0107 0.01
Echinococcus multilocularis shaker cognate 0.0036 0.0224 0.0218
Mycobacterium ulcerans monoxygenase 0.0071 0.0596 0.2097
Loa Loa (eye worm) hypothetical protein 0.0031 0.017 0.0302
Echinococcus granulosus peregrin 0.0029 0.0156 0.0149
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.013 0.1216 0.121
Schistosoma mansoni hypothetical protein 0.0016 0.0014 0.0008
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0236
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.2942 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0061 0.0054
Echinococcus multilocularis calmodulin 0.0025 0.0107 0.01
Toxoplasma gondii histone deacetylase HDAC4 0.0133 0.1248 0.2379
Schistosoma mansoni hypothetical protein 0.0411 0.4178 0.4536
Loa Loa (eye worm) hypothetical protein 0.0078 0.0672 0.1197
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.1231 0.1225
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0132 0.0448
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0015 0.001
Echinococcus multilocularis calmodulin 0.0025 0.0107 0.01
Loa Loa (eye worm) histone deacetylase 0.0508 0.5201 0.9261
Loa Loa (eye worm) hypothetical protein 0.0065 0.0538 0.0957
Schistosoma mansoni microtubule-associated protein tau 0.0693 0.7155 0.7773
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0323 0.1098
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0131 0.1231 0.1225
Echinococcus multilocularis somatostatin receptor 0.0131 0.1231 0.1225
Brugia malayi Pre-SET motif family protein 0.021 0.2058 0.3372
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.1231 0.1225
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0291 0.2911 0.9894
Loa Loa (eye worm) hypothetical protein 0.0214 0.2099 0.3737
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0175 0.1692 0.3566
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0041 0.0276 0.0293
Trypanosoma cruzi histone deacetylase, putative 0.0508 0.5201 0.6735
Trichomonas vaginalis calmodulin, putative 0.0025 0.0107 0.0362
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0268 0.2669 1
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0041 0.0276 0.0269
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0041 0.0282 0.0462
Echinococcus granulosus TRP transient receptor potential channel 0.0036 0.0224 0.0218
Trypanosoma cruzi calmodulin, putative 0.0025 0.0107 0.0129
Loa Loa (eye worm) voltage-gated calcium channel 0.0036 0.0224 0.0399
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0082 0.0712 0.1483
Loa Loa (eye worm) hypothetical protein 0.0027 0.0128 0.0227
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Treponema pallidum NADH oxidase 0.0268 0.2669 0.9058
Echinococcus granulosus g protein coupled receptor 0.0131 0.1231 0.1225
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0071 0.0596 0.1446
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0114 0.0192
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0036 0.0224 0.0218
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0041 0.0282 0.0502
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0071 0.0596 0.2097
Echinococcus multilocularis calcium activated potassium channel 0.0036 0.0229 0.0222
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0071 0.0596 0.059
Echinococcus granulosus survival motor neuron protein 1 0.0237 0.2351 0.2346
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Schistosoma mansoni 60S ribosomal protein L21 0.0039 0.026 0.0275
Loa Loa (eye worm) hypothetical protein 0.0041 0.0282 0.0502
Trypanosoma brucei histone deacetylase 3 0.0508 0.5201 0.6735
Echinococcus granulosus geminin 0.017 0.1642 0.1636
Loa Loa (eye worm) hypothetical protein 0.004 0.0265 0.0471
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0061 0.0109
Schistosoma mansoni biogenic amine receptor 0.0131 0.1231 0.1331
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0041 0.0276 0.0269
Schistosoma mansoni voltage-gated potassium channel 0.0074 0.0625 0.0672
Schistosoma mansoni nuclear hormone receptor 0.002 0.0061 0.0059
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0071 0.0596 0.0977
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0387 0.0493
Loa Loa (eye worm) hypothetical protein 0.0237 0.2351 0.4187
Loa Loa (eye worm) hypothetical protein 0.005 0.0377 0.067
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0131 0.1231 0.1225
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0041 0.0282 0.0515
Entamoeba histolytica disulphide oxidoreductase, putative 0.0071 0.0596 0.1899
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.0323 0.041
Echinococcus granulosus alpha 1A adrenergic receptor 0.0131 0.1231 0.1225
Schistosoma mansoni neuropeptide receptor 0.0131 0.1231 0.1331
Treponema pallidum oxidoreductase 0.0071 0.0596 0.1899
Echinococcus granulosus tyrosine protein kinase Fyn 0.0039 0.0255 0.0248
Trypanosoma cruzi histone deacetylase 1, putative 0.0291 0.2911 0.3766
Echinococcus granulosus sex peptide receptor 0.0131 0.1231 0.1225
Echinococcus multilocularis two pore calcium channel protein 1 0.0036 0.0224 0.0218
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0036 0.0224 0.0367
Leishmania major hypothetical protein, conserved 0.0036 0.0224 0.0282
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0292 0.0993
Trichomonas vaginalis aldehyde oxidase, putative 0.0174 0.1682 0.5717
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.2582 0.8776
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.013 0.1216 0.121
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.007 0.058 0.0574
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0035 0.0031
Plasmodium falciparum glutathione reductase 0.0268 0.2669 0.5119
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0238 0.0252
Onchocerca volvulus Calmodulin homolog 0.0025 0.0107 0.0195
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.1231 0.1331
Giardia lamblia Fructose-bisphosphate aldolase 0.0294 0.2942 1
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0044 0.0312 0.0305
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0399
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0268 0.2669 0.3452
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0186 0.1803 0.1798
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.017 0.0177
Toxoplasma gondii thioredoxin reductase 0.0462 0.4719 0.9071
Brugia malayi hypothetical protein 0.0041 0.0282 0.0462
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0358 0.0586
Giardia lamblia PHD finger protein 15 0.0029 0.0156 0.0378
Trypanosoma brucei calmodulin 0.0025 0.0107 0.0129
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0238 0.0232
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0238 0.03
Schistosoma mansoni neuropeptide receptor 0.0131 0.1231 0.1331
Echinococcus granulosus voltage dependent calcium channel 0.013 0.1216 0.121
Echinococcus multilocularis jun protein 0.0084 0.0737 0.073
Loa Loa (eye worm) ion channel NompC 0.0036 0.0224 0.0399
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0023 0.0089 0.0082
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0186 0.1803 0.1798
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0061 0.0109
Echinococcus granulosus neuropeptide receptor 0.0131 0.1231 0.1225
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0224 0.0218
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Loa Loa (eye worm) glutamate receptor 1 0.0163 0.1562 0.2781
Echinococcus granulosus histone deacetylase 1 0.0291 0.2911 0.2906
Echinococcus granulosus glutamate NMDA receptor subunit 0.0329 0.3316 0.3311
Echinococcus granulosus chromobox protein 1 0.007 0.0585 0.0579
Schistosoma mansoni glutamate receptor kainate 0.0163 0.1562 0.1691
Onchocerca volvulus 0.0071 0.0596 0.2282
Echinococcus granulosus g protein coupled receptor 0.0131 0.1231 0.1225
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0037 0.0126
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0435 0.4436 0.5743
Onchocerca volvulus 0.0131 0.1231 0.4988
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0015 0.0008
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0095 0.0185
Echinococcus granulosus two pore calcium channel protein 2 0.0036 0.0224 0.0218
Leishmania major calmodulin, putative 0.0025 0.0107 0.0129
Trypanosoma brucei histone deacetylase 4 0.0508 0.5201 0.6735
Brugia malayi Furin-like cysteine rich region family protein 0.0151 0.1438 0.2355
Entamoeba histolytica DNA topoisomerase II, putative 0.014 0.1327 0.4424
Echinococcus granulosus two pore calcium channel protein 1 0.0036 0.0224 0.0218
Echinococcus multilocularis histone deacetylase 6 0.0508 0.5201 0.5197
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0294 0.2942 1
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0028 0.0144 0.0354
Echinococcus granulosus hypothetical protein 0.0824 0.8539 0.8538
Echinococcus granulosus transient receptor potential cation channel 0.0036 0.0227 0.022
Echinococcus granulosus tyrosine protein kinase Lyn 0.0039 0.026 0.0253
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.2942 1
Echinococcus granulosus dro:myosuppressin receptor 0.0131 0.1231 0.1225
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0045 0.0049
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.1111 0.1979
Brugia malayi ecdysteroid receptor 0.002 0.0061 0.01
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0071 0.0596 0.1122
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0131 0.1231 0.1225
Plasmodium vivax DNA topoisomerase II, putative 0.014 0.1327 0.2531
Leishmania major hypothetical protein, conserved 0.0025 0.0114 0.0139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0007 0.0023
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0131 0.1231 0.4988
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0071 0.0596 0.1122
Echinococcus multilocularis geminin 0.017 0.1642 0.1636
Loa Loa (eye worm) norepinephrine transporter 0.0243 0.2408 0.4287
Echinococcus granulosus insulin receptor 0.0049 0.0363 0.0356
Loa Loa (eye worm) hepatopoietin HPO2 0.0034 0.0211 0.0374
Echinococcus granulosus biogenic amine 5HT receptor 0.0376 0.381 0.3806
Echinococcus granulosus epidermal growth factor receptor 0.0151 0.1438 0.1432
Schistosoma mansoni sodium-dependent amino acid transporter 0.0041 0.0282 0.0299
Onchocerca volvulus 0.0036 0.0224 0.0697
Brugia malayi hypothetical protein 0.0131 0.1231 0.2017
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Loa Loa (eye worm) transcription factor SMAD2 0.012 0.1111 0.1979
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0041 0.0282 0.0462
Mycobacterium ulcerans hypothetical protein 0.002 0.0061 0.0055
Echinococcus granulosus tyrosine protein kinase Src64B 0.0039 0.0255 0.0248
Loa Loa (eye worm) G-protein coupled receptor 0.0131 0.1231 0.2192
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0114 0.0192
Onchocerca volvulus Histone deacetylase 10 homolog 0.0133 0.1248 0.506
Echinococcus granulosus transient receptor potential gamma protein 0.0036 0.0224 0.0218
Schistosoma mansoni DNA topoisomerase II 0.014 0.1327 0.1436
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0243 0.2408 0.3945
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0227 0.022
Plasmodium vivax amine transporter, putative 0.0041 0.0282 0.0515
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0596 0.0764
Onchocerca volvulus 0.0131 0.1231 0.4988
Echinococcus multilocularis neuropeptides capa receptor 0.0131 0.1231 0.1225
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0071 0.0596 0.2027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0226 0.0768
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0071 0.0596 0.059
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0041 0.0282 0.0275
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0546 0.054
Echinococcus granulosus nmda type glutamate receptor 0.0102 0.0924 0.0918
Schistosoma mansoni tyrosine kinase 0.0082 0.0707 0.0761
Loa Loa (eye worm) glutamate receptor 2 0.0163 0.1562 0.2781
Schistosoma mansoni sodium/chloride dependent transporter 0.0042 0.0287 0.0304
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.0323 0.0956
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0046 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0201 0.0684
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0005 0.0017
Plasmodium falciparum histone deacetylase 2 0.0508 0.5201 1
Plasmodium vivax thioredoxin reductase, putative 0.0462 0.4719 0.9071
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0211 0.0264
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.013 0.1216 0.121
Echinococcus multilocularis glutamate synthase 0.0071 0.0596 0.059
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.1231 0.1331
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0061 0.0054
Echinococcus granulosus dnaJ subfamily B 0.0411 0.4178 0.4174
Echinococcus multilocularis fmrfamide receptor 0.0131 0.1231 0.1225
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0387 0.038
Schistosoma mansoni hypothetical protein 0.0131 0.1231 0.1331
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.007 0.0589 0.0583
Echinococcus granulosus lamin dm0 0.0027 0.0133 0.0126
Echinococcus granulosus DNA topoisomerase 2 alpha 0.014 0.1327 0.1321
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0133 0.1248 0.1609
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0053 0.0086
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0131 0.1231 0.1225
Echinococcus multilocularis allatostatin A receptor 0.0131 0.1231 0.1225
Schistosoma mansoni rab6-interacting 0.004 0.0265 0.0281
Brugia malayi MH2 domain containing protein 0.012 0.1111 0.1821
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0053 0.0093
Brugia malayi hypothetical protein 0.004 0.0265 0.0434
Loa Loa (eye worm) hypothetical protein 0.0025 0.0107 0.0189
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0061 0.0003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0109 0.0193
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0546 0.0699
Echinococcus multilocularis cpg binding protein 0.003 0.0169 0.0162
Loa Loa (eye worm) hypothetical protein 0.0376 0.381 0.6785
Schistosoma mansoni hypothetical protein 0.0034 0.0208 0.0219
Plasmodium falciparum phd finger protein, putative 0.0029 0.0156 0.0273
Schistosoma mansoni calmodulin 0.0025 0.0107 0.0108
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Schistosoma mansoni voltage-gated potassium channel 0.0074 0.0625 0.0672
Chlamydia trachomatis glutamine binding protein 0.0038 0.0248 0.0594
Brugia malayi Pre-SET motif family protein 0.0031 0.017 0.0278
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.1231 0.1225
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.2582 0.8776
Echinococcus multilocularis musashi 0.0027 0.0133 0.0126
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0084 0.0737 0.073
Onchocerca volvulus 0.004 0.0265 0.087
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0061 0.0054
Schistosoma mansoni growth hormone secretagogue receptor 0.0131 0.1231 0.1331
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0071 0.0596 0.1446
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0077 0.0659 0.1079
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Plasmodium falciparum ferrodoxin reductase-like protein 0.0071 0.0596 0.1122
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0036 0.0224 0.0218
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0071 0.0596 0.2027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0104 0.0354
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0061 0.01
Trypanosoma brucei trypanothione reductase 0.0462 0.4719 0.611
Loa Loa (eye worm) ryanodine receptor 0.0036 0.0224 0.0399
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0186 0.1803 0.1798
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0061 0.0059
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0131 0.1231 0.1225
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0092 0.0818 0.1051
Trypanosoma brucei NADH dehydrogenase 0.0071 0.0596 0.0764
Toxoplasma gondii hypothetical protein 0.0041 0.0282 0.0515
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0059 0.0467 0.1602
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0197 0.0389
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.007 0.058 0.0574
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Schistosoma mansoni glutamate receptor NMDA 0.0329 0.3316 0.3598
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0236
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0041 0.0282 0.0275
Brugia malayi hypothetical protein 0.0066 0.0546 0.0894
Brugia malayi hypothetical protein 0.0025 0.0114 0.0187
Echinococcus granulosus metabotropic glutamate receptor 5 0.0023 0.0089 0.0082
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0114 0.0192
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0236
Brugia malayi G-protein coupled receptor 0.0131 0.1231 0.2017
Brugia malayi PHD-finger family protein 0.0029 0.0156 0.0255
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1738 0.5908
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.1642 0.558
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0175 0.1692 0.3566
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0083 0.0728 0.1192
Echinococcus multilocularis chromobox protein 1 0.007 0.0585 0.0579
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0036 0.0224 0.0236
Echinococcus multilocularis calmodulin 0.0025 0.0107 0.01
Loa Loa (eye worm) hypothetical protein 0.0057 0.0449 0.08
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0238 0.0232
Brugia malayi Adenylyl cyclase protein 0.0078 0.0672 0.1101
Schistosoma mansoni chromobox protein 0.007 0.0585 0.0629
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0061 0.01
Onchocerca volvulus 0.0023 0.0089 0.0119
Brugia malayi follicle stimulating hormone receptor 0.0131 0.1231 0.2017
Schistosoma mansoni biogenic amine (5HT) receptor 0.0376 0.381 0.4136
Echinococcus multilocularis neuropeptides capa receptor 0.0131 0.1231 0.1225
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.017 0.0163
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0131 0.1231 0.2017
Loa Loa (eye worm) hypothetical protein 0.0547 0.5616 1
Echinococcus granulosus GPCR family 2 0.0016 0.0014 0.0007
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0061 0.0059
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0061 0.0059
Echinococcus multilocularis g protein coupled receptor 0.0131 0.1231 0.1225
Toxoplasma gondii endonuclease IV APN 0.0077 0.0659 0.1242
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0016 0.0021 0.007
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.1231 0.1225
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0046 0.0076
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0462 0.4719 1
Brugia malayi histone deacetylase 3 (HD3) 0.0291 0.2911 0.477
Plasmodium vivax glutathione reductase, putative 0.0462 0.4719 0.9071
Giardia lamblia Calmodulin 0.0025 0.0107 0.0208
Echinococcus granulosus neuropeptide Y receptor 0.0131 0.1231 0.1225
Brugia malayi hypothetical protein 0.0016 0.002 0.0032
Echinococcus granulosus potassium voltage gated channel protein 0.0036 0.0224 0.0218
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0071 0.0596 0.1237
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0265 0.0258
Brugia malayi histone deacetylase 11 0.0133 0.1248 0.2045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0226 0.0768
Brugia malayi hypothetical protein 0.0131 0.1231 0.2017
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0046 0.0061
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0071 0.0596 0.1122
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0041 0.0276 0.0293
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0014 0.0007
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0059 0.0467 0.0961
Echinococcus multilocularis histone deacetylase 7 0.0508 0.5201 0.5197
Brugia malayi putative neuropeptide receptor NPR1 0.0131 0.1231 0.2017
Echinococcus granulosus potassium large conductance calcium activated 0.0036 0.0224 0.0218
Plasmodium vivax calmodulin, putative 0.0025 0.0107 0.0177
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0041 0.0282 0.0462
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0211 0.0378
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0061 0.0054
Onchocerca volvulus 0.0243 0.2408 1
Onchocerca volvulus 0.0131 0.1231 0.4988
Echinococcus granulosus tyrosine protein kinase Fyn 0.0039 0.0255 0.0248
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0211 0.0264
Schistosoma mansoni opsin-like receptor 0.0131 0.1231 0.1331
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0041 0.0282 0.0299
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0071 0.0596 0.0764
Brugia malayi hypothetical protein 0.0131 0.1231 0.2017
Echinococcus multilocularis G protein coupled receptor 139 0.0131 0.1231 0.1225
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0109
Echinococcus granulosus potassium voltage gated channel protein 0.0036 0.0224 0.0218
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0238 0.0732
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0071 0.0596 0.1237
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.1231 0.1331
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0071 0.0596 0.1899
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0071 0.0596 0.1122
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0131 0.1231 0.1225
Echinococcus multilocularis tumor protein p63 0.0339 0.3425 0.3421
Echinococcus multilocularis short transient receptor potential channel 6 0.0036 0.0227 0.022
Schistosoma mansoni transient receptor potential channel 0.0036 0.0224 0.0236
Leishmania major trypanothione reductase 0.0462 0.4719 0.611
Loa Loa (eye worm) hypothetical protein 0.0041 0.0282 0.0502
Schistosoma mansoni biogenic amine receptor 0.0131 0.1231 0.1331
Schistosoma mansoni histone deacetylase 4 5 0.0508 0.5201 0.5648
Echinococcus granulosus CalModulin family member cmd 1 0.0025 0.0107 0.01
Brugia malayi Receptor family ligand binding region containing protein 0.0028 0.0144 0.0235
Echinococcus granulosus L aminoadipate semialdehyde 0.0083 0.0728 0.0721
Loa Loa (eye worm) programmed cell death 8 0.0071 0.0596 0.1062
Echinococcus multilocularis voltage dependent calcium channel 0.013 0.1216 0.121
Echinococcus multilocularis histone deacetylase 8 0.0133 0.1248 0.1242
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0268 0.2669 0.5119
Schistosoma mansoni sulfide quinone reductase 0.0071 0.0596 0.0641
Leishmania major histone deacetylase, putative 0.0508 0.5201 0.6735
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0157
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0238 0.03
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0276 0.0293
Onchocerca volvulus 0.0031 0.0172 0.0472
Echinococcus multilocularis adenylate cyclase 9 0.0078 0.0672 0.0666
Treponema pallidum sodium- and chloride- dependent transporter 0.0243 0.2408 0.8154
Echinococcus multilocularis lamin dm0 0.0027 0.0133 0.0126
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0268 0.2669 1
Echinococcus granulosus serotonin receptor 0.0131 0.1231 0.1225
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0071 0.0596 0.2097
Loa Loa (eye worm) glutathione reductase 0.0462 0.4719 0.8403
Brugia malayi hypothetical protein 0.0131 0.1231 0.2017
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0399
Brugia malayi Blistered cuticle protein 3 0.0073 0.0617 0.101
Echinococcus multilocularis potassium voltage gated channel protein 0.0036 0.0224 0.0218
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Echinococcus multilocularis hyperpolarization activated cyclic 0.0041 0.0276 0.0269
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0036 0.0226 0.0284
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0265 0.0258
Echinococcus multilocularis neuropeptide s receptor 0.0593 0.6103 0.61
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0268 0.2669 0.2664
Loa Loa (eye worm) adenylyl cyclase 3 0.0078 0.0672 0.1197
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0268 0.2669 0.2895
Echinococcus multilocularis glutamate receptor subunit protein glur 0.007 0.058 0.0574
Echinococcus multilocularis dnaJ subfamily B 0.0411 0.4178 0.4174
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0224 0.0218
Trichomonas vaginalis histone deacetylase, putative 0.0291 0.2911 0.9894
Onchocerca volvulus 0.0131 0.1231 0.4988
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0236
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.0323 0.041
Echinococcus granulosus tachykinin peptides receptor 99D 0.0131 0.1231 0.1225
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0095 0.0092
Trichomonas vaginalis set domain proteins, putative 0.0239 0.2362 0.8029
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0387 0.038
Toxoplasma gondii histone deacetylase HDAC2 0.0291 0.2911 0.5585
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.0585 0.1041
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0238 0.03
Trichomonas vaginalis histone deacetylase, putative 0.0291 0.2911 0.9894
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0071 0.0596 0.1899
Echinococcus multilocularis epidermal growth factor receptor 0.0151 0.1438 0.1432
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0227 0.022
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0035 0.0216 0.0209
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.0323 0.0316
Schistosoma mansoni thyroid hormone receptor 0.002 0.0061 0.0059
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0041 0.0282 0.0515
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.1231 0.1225
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.1231 0.1331
Schistosoma mansoni tyrosine kinase 0.0049 0.0363 0.0387
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0041 0.0282 0.0275
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.1738 0.5908
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0041 0.0282 0.0299
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0016 0.0021 0.007
Echinococcus multilocularis epidermal growth factor receptor 0.0082 0.0707 0.0701
Brugia malayi ERG2 and Sigma1 receptor like protein 0.037 0.3746 0.6139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0254 0.0862
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0887 0.9203 0.9202
Trypanosoma cruzi DNA topoisomerase II, putative 0.0133 0.1248 0.1609
Chlamydia trachomatis DNA gyrase subunit A 0.003 0.0166 0.0275
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0156 0.0273
Loa Loa (eye worm) voltage-gated potassium channel 0.0036 0.0224 0.0399
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0132 0.0448
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0015 0.001
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.007 0.058 0.0574
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0095 0.0167
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0036 0.0224 0.0218
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0077 0.0659 0.1242
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0061 0.01
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0034 0.0211 0.0204
Echinococcus granulosus somatostatin receptor 0.0131 0.1231 0.1225
Loa Loa (eye worm) hypothetical protein 0.0044 0.0312 0.0555
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0108 0.0981 0.0975
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.1231 0.1225
Chlamydia trachomatis thioredoxin reductase 0.0071 0.0596 0.1948
Onchocerca volvulus 0.0131 0.1231 0.4988
Brugia malayi DNA topoisomerase II, alpha isozyme 0.014 0.1327 0.2175
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0129 0.0438
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0061 0.0054
Onchocerca volvulus 0.0025 0.0106 0.0194
Echinococcus multilocularis Polycystic kidney disease protein 0.004 0.0265 0.0258
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0015 0.0008
Mycobacterium ulcerans epimerase 0.002 0.0061 0.0055
Leishmania major hypothetical protein, conserved 0.0071 0.0596 0.0764
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0007 0.0023
Brugia malayi Doublecortin family protein 0.004 0.0265 0.0434
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0014 0.0023
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0197 0.192 0.3146
Chlamydia trachomatis DNA gyrase subunit A 0.003 0.0166 0.0275
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0133 0.1248 0.1609
Brugia malayi G-protein coupled receptor 0.0131 0.1231 0.2017
Echinococcus multilocularis microtubule associated protein 2 0.0693 0.7155 0.7153
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0015 0.0008
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0039 0.0255 0.0248
Trichomonas vaginalis chromobox protein, putative 0.007 0.0585 0.1989
Schistosoma mansoni glutamate receptor NMDA 0.0265 0.2639 0.2862
Brugia malayi hypothetical protein 0.0131 0.1231 0.2017
Schistosoma mansoni histone deacetylase hda2 0.0515 0.5276 0.573
Brugia malayi Receptor family ligand binding region containing protein 0.0023 0.0089 0.0145
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0036 0.0224 0.0697
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0061 0.01
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0061 0.0109
Leishmania major mitochondrial DNA topoisomerase II 0.0158 0.1509 0.1947
Echinococcus granulosus sodium and chloride dependent glycine 0.0041 0.0282 0.0275
Plasmodium falciparum histone deacetylase, putative 0.0508 0.5201 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0131 0.1231 0.1225
Onchocerca volvulus 0.0131 0.1231 0.4988
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0036 0.0224 0.0367
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.0323 0.041
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0033 0.0198 0.0389
Trichomonas vaginalis mercuric reductase, putative 0.0268 0.2669 0.9073
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0399
Schistosoma mansoni coup transcription factor 0.002 0.0061 0.0059
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0372 0.3765 0.7973
Schistosoma mansoni jun-related protein 0.0069 0.057 0.0612
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0061 0.0059
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0095 0.0848 0.3352
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0061 0.0099
Brugia malayi voltage-dependent calcium channel 0.0036 0.0224 0.0367
Schistosoma mansoni inositol monophosphatase 0.0037 0.0238 0.0252
Onchocerca volvulus 0.0131 0.1231 0.4988
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0175 0.1692 0.4404
Echinococcus multilocularis rhodopsin orphan GPCR 0.0131 0.1231 0.1225
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.2582 0.8776
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.0323 0.0956
Trypanosoma brucei calmodulin 0.0025 0.0107 0.0129
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0039 0.0255 0.0248
Trypanosoma brucei calmodulin 0.0025 0.0107 0.0129
Toxoplasma gondii transporter, cation channel family protein 0.0054 0.0412 0.0766
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0387 0.0493
Trypanosoma cruzi C-8 sterol isomerase, putative 0.037 0.3746 0.4849
Echinococcus multilocularis conserved hypothetical protein 0.0693 0.7155 0.7153
Schistosoma mansoni two-pore calcium channel 0.0036 0.0224 0.0236
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0131 0.1231 0.1331
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0071 0.0596 0.2097
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0019 0.0053 0.0023
Echinococcus multilocularis receptor type guanylyl cyclase 0.0028 0.0144 0.0137
Leishmania major histone deacetylase, putative 0.0508 0.5201 0.6735
Trypanosoma cruzi histone deacetylase, putative 0.0133 0.1248 0.161
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0037 0.0126
Onchocerca volvulus 0.0078 0.0672 0.2606
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0268 0.2669 0.3452
Brugia malayi glutamate synthase 0.0071 0.0596 0.0977
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.0323 0.041
Echinococcus granulosus intermediate filament protein 0.0027 0.0133 0.0126
Mycobacterium tuberculosis Probable reductase 0.0175 0.1692 0.3566
Loa Loa (eye worm) hypothetical protein 0.0095 0.0849 0.1511
Trichomonas vaginalis DNA topoisomerase II, putative 0.014 0.1327 0.4512
Echinococcus granulosus cpg binding protein 0.003 0.0169 0.0162
Brugia malayi hypothetical protein 0.0036 0.0224 0.0367
Entamoeba histolytica hypothetical protein 0.0023 0.0095 0.0167
Brugia malayi Dopamine receptor protein 2 0.0131 0.1231 0.2017
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0546 0.0699
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0083 0.0728 0.0784
Trypanosoma cruzi histone deacetylase, putative 0.0508 0.5201 0.6735
Echinococcus multilocularis potassium voltage gated channel protein 0.0036 0.0224 0.0218
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0046 0.0082
Leishmania major NADH dehydrogenase, putative 0.0071 0.0596 0.0764
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0071 0.0596 0.1237
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0435 0.0811
Loa Loa (eye worm) hypothetical protein 0.0243 0.2408 0.4287
Echinococcus multilocularis g protein coupled receptor 0.0131 0.1231 0.1225
Echinococcus multilocularis glutamate receptor 2 0.0163 0.1562 0.1556
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0268 0.2669 1
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0036 0.0224 0.0236
Echinococcus granulosus orexin receptor type 2 0.0131 0.1231 0.1225
Echinococcus granulosus allatostatin A receptor 0.0131 0.1231 0.1225
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0238 0.0232
Brugia malayi Cyclic-nucleotide gated cation channel 0.0041 0.0276 0.0452
Entamoeba histolytica hypothetical protein 0.0023 0.0089 0.0146
Entamoeba histolytica protein kinase, putative 0.0031 0.0176 0.0448
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.017 0.0177
Echinococcus multilocularis insulin receptor 0.0049 0.0363 0.0356
Plasmodium vivax multidomain scavenger receptor, putative 0.004 0.0265 0.0483
Schistosoma mansoni thyroid hormone receptor 0.002 0.0061 0.0059
Loa Loa (eye worm) hypothetical protein 0.0382 0.3875 0.69
Echinococcus multilocularis orexin receptor type 2 0.0131 0.1231 0.1225
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0268 0.2669 0.5119
Loa Loa (eye worm) RGC/RGC protein kinase 0.0028 0.0144 0.0256
Onchocerca volvulus 0.0066 0.0546 0.2066
Echinococcus granulosus histone deacetylase 6 0.0508 0.5201 0.5197
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.0323 0.041
Schistosoma mansoni loxhd1 0.004 0.0265 0.0281
Brugia malayi Histone deacetylase 1 0.0291 0.2911 0.477
Brugia malayi protein-tyrosine kinase 0.0035 0.0216 0.0354
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.013 0.1216 0.1315
Echinococcus granulosus tyrosine kinase 0.0035 0.0216 0.0209
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Brugia malayi Serotonin receptor 0.0131 0.1231 0.2017
Echinococcus multilocularis G-protein coupled receptor, putative 0.0131 0.1231 0.1225
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0323 0.0529
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0104 0.0353
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.013 0.1216 0.1315
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0061 0.0054
Entamoeba histolytica histone deacetylase, putative 0.0291 0.2911 0.9892
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0157
Echinococcus multilocularis tyrosine kinase 0.0025 0.0109 0.0102
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0546 0.0895
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0131 0.1231 0.1331
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0041 0.0282 0.0299
Trypanosoma cruzi calmodulin, putative 0.0025 0.0107 0.0129
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Echinococcus multilocularis glutamate receptor 2 0.0116 0.107 0.1064
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0131 0.1231 0.1331
Onchocerca volvulus 0.0027 0.0133 0.0307
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.1642 0.558
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.1231 0.1331
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0071 0.0596 0.2027
Loa Loa (eye worm) hypothetical protein 0.0095 0.0849 0.1511
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0571 0.5865 0.7596
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0201 0.0684
Echinococcus granulosus neuropeptide FF receptor 2 0.0131 0.1231 0.1225
Echinococcus multilocularis transient receptor potential gamma protein 0.0036 0.0224 0.0218
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.0224 0.0236
Schistosoma mansoni hypothetical protein 0.0016 0.0014 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.014 0.0476
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0061
Echinococcus granulosus voltage gated potassium channel 0.0036 0.0224 0.0218
Echinococcus multilocularis 0.0046 0.0336 0.0329
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0387 0.0493
Schistosoma mansoni tyrosine kinase 0.0025 0.0109 0.0111
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0061 0.01
Loa Loa (eye worm) hypothetical protein 0.0131 0.1231 0.2192
Loa Loa (eye worm) hypothetical protein 0.0041 0.0276 0.0491
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0071 0.0596 0.059
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0252 0.0245
Echinococcus multilocularis ryanodine receptor 44f 0.0036 0.0225 0.0218
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.013 0.1216 0.1992
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0095 0.0185
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0061 0.01
Leishmania major cytochrome p450-like protein 0.0019 0.0053 0.0059
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.017 0.0163
Brugia malayi Augmenter of liver regeneration 0.0034 0.0211 0.0345
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0197 0.192 0.3146
Schistosoma mansoni metabotropic glutamate receptor 0.0023 0.0089 0.0089
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0387 0.0718
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0023 0.0089 0.0145
Onchocerca volvulus 0.0131 0.1231 0.4988
Trichomonas vaginalis histone deacetylase, putative 0.0291 0.2911 0.9894
Plasmodium vivax ferrodoxin reductase, putative 0.0071 0.0596 0.1122
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0095 0.0155
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0061 0.0054
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.007 0.0589 0.1049
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0049 0.0363 0.0356
Echinococcus granulosus epidermal growth factor receptor 0.0082 0.0707 0.0701
Echinococcus multilocularis neuropeptide receptor A26 0.0593 0.6103 0.61
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0399
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0211 0.0378
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0387 0.1315
Loa Loa (eye worm) CYP4Cod1 0.0019 0.0053 0.0093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0132 0.0448
Toxoplasma gondii selenide, water dikinase 0.0071 0.0596 0.1122
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0061 0.0109
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0224 0.0218
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.007 0.0589 0.0965
Brugia malayi hypothetical protein 0.0237 0.2351 0.3853
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0133 0.0236
Loa Loa (eye worm) hypothetical protein 0.002 0.0061 0.0109
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.1231 0.1331
Loa Loa (eye worm) solute carrier family 6 member 4 0.0243 0.2408 0.4287
Loa Loa (eye worm) hypothetical protein 0.0243 0.2408 0.4287
Brugia malayi Heterochromatin protein 1 0.007 0.0585 0.0958
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0428 0.4363 0.7149
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0061 0.0059
Echinococcus multilocularis neuropeptide Y receptor 0.0131 0.1231 0.1225
Echinococcus granulosus tyrosine protein kinase Src42A 0.0033 0.0196 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0104 0.0353
Toxoplasma gondii exonuclease III APE 0.0019 0.0046 0.0061
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0131 0.1231 0.1331
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0044 0.0312 0.0305
Toxoplasma gondii histone deacetylase HDAC5 0.0133 0.1251 0.2384
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0131 0.1231 0.1225
Loa Loa (eye worm) inositol-1 0.0037 0.0238 0.0424
Echinococcus multilocularis hyperpolarization activated cyclic 0.0041 0.0276 0.0269
Treponema pallidum quinoline 2-oxidoreductase 0.0028 0.0139 0.0318
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0046 0.0334 0.1135
Echinococcus multilocularis NMDA receptor 0.007 0.058 0.0574
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0131 0.1231 0.1225
Toxoplasma gondii histone deacetylase HDAC1 0.0508 0.5201 1
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0158 0.1509 0.1947
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0082 0.071 0.1342
Echinococcus multilocularis glutamate receptor NMDA 0.0079 0.0682 0.0676
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0224 0.0218
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0042 0.0291 0.0309
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0387 0.1315
Treponema pallidum hypothetical protein 0.0023 0.0093 0.0161
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0041 0.0276 0.0293
Giardia lamblia Histone deacetylase 0.0291 0.2911 0.9892
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0061
Trichomonas vaginalis glutamate synthase, putative 0.0071 0.0596 0.2027
Echinococcus multilocularis GPCR, family 2 0.0016 0.0014 0.0007
Echinococcus granulosus rhodopsin orphan GPCR 0.0131 0.1231 0.1225
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0041 0.0276 0.0269
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0036 0.0226 0.0284
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0504 0.0541
Echinococcus multilocularis dro:myosuppressin receptor 0.0131 0.1231 0.1225
Schistosoma mansoni intermediate filament proteins 0.0027 0.0133 0.0137
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0035 0.0216 0.0209
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.1642 0.558
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0131 0.1231 0.1331
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0038 0.0248 0.0496
Leishmania major calmodulin, putative 0.0025 0.0107 0.0129
Plasmodium falciparum glutathione reductase 0.0462 0.4719 0.9071
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0114 0.0139
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0071 0.0596 0.0764
Brugia malayi jmjC domain containing protein 0.0037 0.0238 0.039
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.2942 1
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0329 0.3316 0.3311
Brugia malayi hypothetical protein 0.004 0.0265 0.0434
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0485 0.0863

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 5.5751 Inhibition of NaV1.7 ion channel (unknown origin) ChEMBL. 23177785

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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