Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0249 | 0.1055 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0037 | 0.1157 | 0.5252 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0889 | 0.3768 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.0326 | 0.1481 |
Schistosoma mansoni | zinc finger protein | 0.0016 | 0.0249 | 0.1055 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.164 | 0.1877 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0018 | 0.0353 | 0.0404 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0326 | 0.1382 |
Trypanosoma brucei | ISWI complex protein | 0.0016 | 0.0249 | 0.5 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0048 | 0.164 | 0.7444 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0048 | 0.164 | 0.6947 |
Echinococcus multilocularis | zinc finger protein | 0.002 | 0.0437 | 0.1985 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1264 | 0.1447 |
Brugia malayi | Pre-SET motif family protein | 0.0031 | 0.0889 | 0.1018 |
Brugia malayi | Bromodomain containing protein | 0.0077 | 0.2876 | 0.3293 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0484 | 0.2049 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.0326 | 0.1481 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0213 | 0.8735 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0048 | 0.164 | 0.7444 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0061 | 0.2203 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0037 | 0.1157 | 0.5252 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.2688 | 0.3077 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0.0889 | 0.4037 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.0484 | 0.0554 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0841 | 0.3818 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1368 | 0.1567 |
Echinococcus granulosus | zinc finger protein | 0.002 | 0.0437 | 0.1985 |
Plasmodium vivax | SET domain protein, putative | 0.0031 | 0.0889 | 0.5 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0061 | 0.2203 | 1 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0326 | 0.1382 |
Brugia malayi | Pre-SET motif family protein | 0.0213 | 0.8735 | 1 |
Brugia malayi | PHD-finger family protein | 0.0025 | 0.0672 | 0.0769 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0568 | 0.2405 |
Schistosoma mansoni | zinc finger protein | 0.002 | 0.0437 | 0.1852 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0031 | 0.0889 | 0.5 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0568 | 0.2577 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.1261 | 0.1444 |
Leishmania major | hypothetical protein, conserved | 0.0016 | 0.0249 | 0.5 |
Trypanosoma cruzi | ISWI complex protein | 0.0016 | 0.0249 | 0.5 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.0889 | 0.3768 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.1453 | 0.1663 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0048 | 0.164 | 0.6947 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0568 | 0.2577 |
Schistosoma mansoni | bromodomain containing protein | 0.0065 | 0.2361 | 1 |
Trypanosoma cruzi | ISWI complex protein | 0.0016 | 0.0249 | 0.5 |
Onchocerca volvulus | 0.0031 | 0.0889 | 0.0889 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.