TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 316.357 | Formula: C19H16N4O
H donors: 1 H acceptors: 4 LogP: 2.14 Rotable bonds: 4
Rule of 5 violations (Lipinski): 1
SMILES: OCc1cc(nc2c1cnn2Cc1ccncc1)c1ccccc1
InChi: 1S/C19H16N4O/c24-13-16-10-18(15-4-2-1-3-5-15)22-19-17(16)11-21-23(19)12-14-6-8-20-9-7-14/h1-11,24H,12-13H2
InChiKey: BVDWAKQGKDIXNR-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0045	0.0795	0.2776
Brugia malayi	Steroid receptor seven-up type 2	0.001	0.0108	0.0377
Brugia malayi	Latrophilin receptor protein 2	0.0016	0.0221	0.0773
Brugia malayi	MH2 domain containing protein	0.0008	0.007	0.0245
Entamoeba histolytica	hypothetical protein	0.0037	0.0644	1
Schistosoma mansoni	hypothetical protein	0.0016	0.0221	0.0216
Echinococcus granulosus	histone lysine N methyltransferase MLL3	0.0007	0.0053	0.0048
Entamoeba histolytica	hypothetical protein	0.0037	0.0644	1
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.001	0.0108	0.0103
Loa Loa (eye worm)	histone methyltransferase	0.0009	0.0087	0.0304
Brugia malayi	orphan nuclear receptor NR2E1	0.0005	0.0005	0.0018
Brugia malayi	Nuclear hormone receptor-like 1	0.0005	0.0016	0.0057
Brugia malayi	nuclear receptor RXR	0.0005	0.0016	0.0057
Loa Loa (eye worm)	hypothetical protein	0.0146	0.2793	0.975
Echinococcus granulosus	mixed lineage leukemia protein mll	0.0007	0.0053	0.0048
Schistosoma mansoni	hypothetical protein	0.0016	0.0221	0.0216
Echinococcus multilocularis	GPCR, family 2	0.0016	0.0221	0.0216
Echinococcus multilocularis	histone lysine N methyltransferase MLL3	0.0009	0.0087	0.0082
Echinococcus granulosus	FTZ F1 alpha	0.0387	0.7523	0.7522
Schistosoma mansoni	cpg binding protein	0.003	0.0508	0.0503
Brugia malayi	hypothetical protein	0.0005	0.0016	0.0057
Schistosoma mansoni	ap endonuclease	0.0019	0.0281	0.0276
Echinococcus multilocularis	mothers against decapentaplegic 5	0.0008	0.007	0.0065
Onchocerca volvulus		0.0029	0.0475	0.1644
Trypanosoma brucei	apurinic/apyrimidinic endonuclease, putative	0.0019	0.0281	0.5
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0005	0.0018
Mycobacterium ulcerans	exodeoxyribonuclease III protein XthA	0.0019	0.0281	0.5
Schistosoma mansoni	thyroid hormone receptor	0.001	0.0108	0.0103
Entamoeba histolytica	hypothetical protein	0.0037	0.0644	1
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.001	0.0108	0.0103
Brugia malayi	Muscleblind-like protein	0.0146	0.2793	0.975
Brugia malayi	ecdysone receptor	0.0005	0.0005	0.0018
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.001	0.0108	0.0377
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.001	0.0108	0.036
Echinococcus granulosus	mothers against decapentaplegic 5	0.0008	0.007	0.0065
Plasmodium falciparum	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0019	0.0281	0.5
Loa Loa (eye worm)	MH1 domain-containing protein	0.0008	0.007	0.0245
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease, putative	0.0019	0.0281	0.5
Onchocerca volvulus		0.001	0.0108	0.036
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0045	0.0795	0.2776
Echinococcus multilocularis	mixed lineage leukemia protein mll	0.0007	0.0053	0.0048
Onchocerca volvulus	Protein ultraspiracle homolog	0.001	0.0108	0.036
Loa Loa (eye worm)	hypothetical protein	0.001	0.0108	0.0377
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0045	0.0795	0.079
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.001	0.0108	0.0377
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease	0.0019	0.0281	0.5
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.001	0.0108	0.0103
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0016	0.0221	0.0216
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.001	0.0108	0.0103
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.001	0.0108	0.0377
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.001	0.0108	0.0377
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0221	0.0773
Brugia malayi	nuclear receptor subfamily 1, group D, member 1, putative	0.0005	0.0005	0.0018
Brugia malayi	latrophilin 2 splice variant baaae	0.0034	0.0579	0.2021
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0029	0.0475	0.166
Loa Loa (eye worm)	MH2 domain-containing protein	0.0117	0.2215	0.7732
Brugia malayi	nuclear receptor NHR-88	0.0005	0.0005	0.0018
Loa Loa (eye worm)	DR-78	0.0005	0.0005	0.0018
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.001	0.0108	0.0103
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.001	0.0108	0.0103
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.001	0.0108	0.0377
Schistosoma mansoni	cpg binding protein	0.0029	0.0475	0.0471
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.001	0.0108	0.0103
Brugia malayi	F/Y-rich N-terminus family protein	0.0009	0.0085	0.0297
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0005	0.0018
Schistosoma mansoni	RAR-like nuclear receptor	0.001	0.0108	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0005	0.0018
Brugia malayi	hypothetical protein	0.015	0.2865	1
Brugia malayi	nuclear hormone receptor	0.0005	0.0005	0.0018
Loa Loa (eye worm)	nuclear hormone receptor	0.0005	0.0005	0.0018
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0016	0.0057
Brugia malayi	tailless protein	0.0005	0.0005	0.0018
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.001	0.0108	0.0103
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.001	0.0108	0.0377
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0037	0.0644	0.0639
Schistosoma mansoni	smad1 5 8 and	0.0008	0.007	0.0065
Echinococcus granulosus	cpg binding protein	0.003	0.0508	0.0503
Echinococcus multilocularis	histone lysine N methyltransferase MLL3	0.0007	0.0053	0.0048
Loa Loa (eye worm)	steroid hormone receptor	0.001	0.0108	0.0377
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.001	0.0108	0.0377
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.001	0.0108	0.0377
Schistosoma mansoni	hypothetical protein	0.0034	0.0579	0.0574
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.001	0.0108	0.0103
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.001	0.0108	0.0377
Echinococcus multilocularis	smad	0.0008	0.007	0.0065
Schistosoma mansoni	transcription factor LCR-F1	0.0037	0.0644	0.0639
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.001	0.0108	0.0103
Loa Loa (eye worm)	transcription factor SMAD2	0.0117	0.2215	0.7732
Onchocerca volvulus	Bile acid receptor homolog	0.001	0.0108	0.036
Brugia malayi	nuclear receptor NHR-67	0.0005	0.0005	0.0018
Echinococcus multilocularis	TGF beta signal transducer SmadC	0.0008	0.007	0.0065
Plasmodium vivax	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0019	0.0281	0.5
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0016	0.0221	0.0773
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.001	0.0108	0.0377
Loa Loa (eye worm)	Smad1	0.0008	0.007	0.0245
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0016	0.0221	0.0773
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0049	0.0887	0.3096
Loa Loa (eye worm)	hypothetical protein	0.001	0.0108	0.0377
Echinococcus granulosus	DNA apurinic or apyrimidinic site lyase	0.0019	0.0281	0.0276
Loa Loa (eye worm)	hypothetical protein	0.001	0.0108	0.0377
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0045	0.0795	0.079
Brugia malayi	CXXC zinc finger family protein	0.0029	0.0475	0.166
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0037	0.0644	0.0639
Loa Loa (eye worm)	hypothetical protein	0.015	0.2865	1
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.001	0.0108	0.0377
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.001	0.0108	0.0377
Schistosoma mansoni	hypothetical protein	0.0016	0.0221	0.0216
Echinococcus granulosus	smad	0.0008	0.007	0.0065
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.001	0.0108	0.0377
Loa Loa (eye worm)	nuclear receptor NHR-67	0.0005	0.0005	0.0018
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0045	0.0795	0.079
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0045	0.0795	0.079
Schistosoma mansoni	hypothetical protein	0.0016	0.0221	0.0216
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.001	0.0108	0.0377
Loa Loa (eye worm)	hypothetical protein	0.001	0.0108	0.0377
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0016	0.0221	0.0216
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0005	0.0018
Schistosoma mansoni	thyroid hormone receptor	0.001	0.0108	0.0103
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.001	0.0108	0.0377
Leishmania major	apurinic/apyrimidinic endonuclease-redox protein	0.0019	0.0281	0.5
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0016	0.0221	0.0216
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0054	0.0978	1
Loa Loa (eye worm)	MH2 domain-containing protein	0.0008	0.007	0.0245
Echinococcus granulosus	TGF beta signal transducer SmadC	0.0008	0.007	0.0065
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0061	0.1106	0.1101
Brugia malayi	conserved hypotetical protein	0.0005	0.0005	0.0018
Wolbachia endosymbiont of Brugia malayi	exonuclease III	0.0019	0.0281	0.5
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0016	0.0057
Echinococcus granulosus	nuclear receptor subfamily 1 group D	0.0005	0.0016	0.0011
Brugia malayi	Nuclear hormone receptor E75	0.0005	0.0005	0.0018
Echinococcus multilocularis	muscleblind protein	0.0146	0.2793	0.279
Schistosoma mansoni	nuclear hormone receptor	0.001	0.0108	0.0103
Brugia malayi	Nuclear hormone receptor-like 1	0.0005	0.0016	0.0057
Schistosoma mansoni	TGF-beta signal transducer Smad2	0.0008	0.007	0.0065
Echinococcus multilocularis	DNA (apurinic or apyrimidinic site) lyase	0.0019	0.0281	0.0276
Echinococcus multilocularis	cpg binding protein	0.003	0.0508	0.0503
Echinococcus multilocularis	thyroid hormone receptor alpha	0.001	0.0108	0.0103
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.001	0.0108	0.0377
Treponema pallidum	exodeoxyribonuclease (exoA)	0.0019	0.0281	0.5
Schistosoma mansoni	hypothetical protein	0.0037	0.0644	0.0639
Schistosoma mansoni	cpg binding protein	0.003	0.0508	0.0503
Brugia malayi	photoreceptor-specific nuclear receptor	0.001	0.0108	0.0377
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0016	0.0057
Loa Loa (eye worm)	hypothetical protein	0.001	0.0108	0.0377
Loa Loa (eye worm)	hypothetical protein	0.0146	0.2793	0.975
Trichomonas vaginalis	ap endonuclease, putative	0.0019	0.0281	1
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0005	0.0018
Echinococcus granulosus	GPCR family 2	0.0016	0.0221	0.0216
Brugia malayi	hypothetical protein	0.0005	0.0005	0.0018
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0005	0.0018
Loa Loa (eye worm)	hypothetical protein	0.001	0.0108	0.0377
Echinococcus multilocularis	Smad4	0.0008	0.007	0.0065
Onchocerca volvulus		0.015	0.2865	1
Schistosoma mansoni	smad1 5 8 and	0.0008	0.007	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0005	0.0018
Brugia malayi	nuclear hormone receptor family member nhr-6	0.0005	0.0005	0.0018
Brugia malayi	Smad1	0.0008	0.007	0.0245
Echinococcus granulosus	histone lysine N methyltransferase MLL3	0.0009	0.0087	0.0082
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0045	0.0795	0.079
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.001	0.0108	0.0103
Brugia malayi	nuclear receptor NHR-88	0.001	0.0108	0.0377
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0016	0.0221	0.0216
Brugia malayi	MH1 domain containing protein	0.0008	0.007	0.0245
Entamoeba histolytica	hypothetical protein	0.0037	0.0644	1
Giardia lamblia	Endonuclease/Exonuclease/phosphatase	0.0019	0.0281	0.5
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0007	0.0053	0.0048
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.001	0.0108	0.0103
Brugia malayi	Nuclear hormone receptor-like 1	0.001	0.0108	0.0377
Schistosoma mansoni	hypothetical protein	0.0407	0.792	0.7919
Schistosoma mansoni	ap endonuclease	0.0019	0.0281	0.0276
Brugia malayi	nuclear receptor RXR	0.0005	0.0005	0.0018
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.001	0.0108	0.0103
Schistosoma mansoni	steroid hormone receptor ad4bp	0.001	0.0108	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0005	0.0018
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.001	0.0108	0.0377
Echinococcus granulosus	dnaJ subfamily B	0.0407	0.792	0.7919
Schistosoma mansoni	smad1 5 8 and	0.0008	0.007	0.0065
Echinococcus multilocularis	FTZ F1 alpha	0.001	0.0108	0.0103
Brugia malayi	ecdysteroid receptor	0.001	0.0108	0.0377
Loa Loa (eye worm)	hypothetical protein	0.001	0.0108	0.0377
Loa Loa (eye worm)	hypothetical protein	0.0049	0.0887	0.3096
Brugia malayi	steroid hormone receptor	0.001	0.0108	0.0377
Brugia malayi	nuclear hormone receptor family member odr-7	0.0005	0.0005	0.0018
Schistosoma mansoni	ecdysone-induced protein 78c (dr-78)	0.0005	0.0016	0.0011
Loa Loa (eye worm)	exodeoxyribonuclease III family protein	0.0019	0.0281	0.098
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.001	0.0108	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0005	0.0018
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.001	0.0108	0.0377
Echinococcus multilocularis	nuclear receptor subfamily 1 group D	0.0005	0.0016	0.0011
Brugia malayi	MH2 domain containing protein	0.0008	0.007	0.0245
Brugia malayi	exodeoxyribonuclease III family protein	0.0019	0.0281	0.098
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.001	0.0108	0.0103
Echinococcus granulosus	ecdysone induced protein 78C	0.001	0.0108	0.0103
Brugia malayi	hypothetical protein	0.0037	0.0644	0.2248
Echinococcus multilocularis	muscleblind protein 1	0.0146	0.2793	0.279
Brugia malayi	MH2 domain containing protein	0.0117	0.2215	0.7732
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0045	0.0795	0.079
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0045	0.0795	0.079
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.001	0.0108	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0034	0.0579	0.2021
Brugia malayi	hypothetical protein	0.0005	0.0016	0.0057
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0016	0.0057
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0005	0.0018
Loa Loa (eye worm)	hypothetical protein	0.001	0.0108	0.0377
Echinococcus granulosus	muscleblind protein	0.0146	0.2793	0.279
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0005	0.0018
Loa Loa (eye worm)	nuclear hormone receptor-like 1	0.0005	0.0016	0.0057
Brugia malayi	hypothetical protein	0.0005	0.0005	0.0018
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0005	0.0018
Schistosoma mansoni	retinoic acid receptor RXR	0.001	0.0108	0.0103
Mycobacterium tuberculosis	Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI)	0.0019	0.0281	0.5
Echinococcus granulosus	Smad4	0.0008	0.007	0.0065
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0016	0.0057
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.001	0.0108	0.0103
Schistosoma mansoni	Smad4	0.0008	0.007	0.0065
Brugia malayi	MH1 domain containing protein	0.0008	0.007	0.0245
Brugia malayi	nuclear hormone receptor	0.001	0.0108	0.0377
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0049	0.0887	0.3096
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0005	0.0018
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.001	0.0108	0.0377
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.001	0.0108	0.0103
Loa Loa (eye worm)	nuclear receptor nhr-7B	0.0005	0.0005	0.0018
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0005	0.0016	0.0011
Schistosoma mansoni	coup transcription factor	0.001	0.0108	0.0103
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.001	0.0108	0.0103
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0049	0.0887	0.3096
Schistosoma mansoni	smad	0.0008	0.007	0.0065
Trichomonas vaginalis	ap endonuclease, putative	0.0019	0.0281	1
Echinococcus multilocularis	dnaJ subfamily B	0.0407	0.792	0.7919
Echinococcus multilocularis	ecdysone induced protein 78C	0.001	0.0108	0.0103
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.001	0.0108	0.0377
Brugia malayi	Nuclear hormone receptor E75	0.0005	0.0005	0.0018

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2324874

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1729319