Detailed information for compound 1730608

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 248.321 | Formula: C14H20N2O2
  • H donors: 0 H acceptors: 0 LogP: 2.53 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccccc1/C=N/OC1CCCN(C1)C
  • InChi: 1S/C14H20N2O2/c1-16-9-5-7-13(11-16)18-15-10-12-6-3-4-8-14(12)17-2/h3-4,6,8,10,13H,5,7,9,11H2,1-2H3/b15-10+
  • InChiKey: KYJDTCBDFAWZCM-XNTDXEJSSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0189 0.099 0.134
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0017 0.0023
Brugia malayi CXXC zinc finger family protein 0.0029 0.0102 0.0138
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0014 0.0017 0.0023
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0082 0.0082
Leishmania major cytochrome p450-like protein 0.002 0.0049 0.0049
Schistosoma mansoni multidrug resistance protein 0.0034 0.0132 0.0179
Schistosoma mansoni thyroid hormone receptor 0.0014 0.0017 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0014 0.0017 0.0023
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0023
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0137 0.0137
Onchocerca volvulus 0.0049 0.0211 0.038
Loa Loa (eye worm) hypothetical protein 0.0087 0.0424 0.0574
Echinococcus multilocularis tumor protein p63 0.0341 0.1837 0.2486
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0014 0.0017 0.0023
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0132 0.0132
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0132 0.0132
Trypanosoma brucei membrane transporter protein, putative 0.0034 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0023
Trichomonas vaginalis beta-hexosaminidase, putative 0.0234 0.1242 0.4497
Echinococcus multilocularis ecdysone induced protein 78C 0.0014 0.0017 0.0023
Brugia malayi hypothetical protein 0.0238 0.1268 0.1716
Brugia malayi hypothetical protein 0.0016 0.0032 0.0043
Brugia malayi photoreceptor-specific nuclear receptor 0.0014 0.0017 0.0023
Loa Loa (eye worm) glycosyl hydrolase family 20 0.0374 0.2024 0.2738
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0014 0.0017 0.0023
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0029 0.0029
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0011 0.0002 0.0002
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0189 0.099 0.134
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0014 0.0017 0.0023
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0218 0.0295
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0004 0.0005
Brugia malayi Cytochrome P450 family protein 0.002 0.0049 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0014 0.0017 0.0023
Leishmania major basic transcription factor 3a, putative 0.0035 0.0137 0.0137
Echinococcus multilocularis dnaJ subfamily B 0.0412 0.2237 0.3026
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0014 0.0017 0.0023
Onchocerca volvulus Hexosaminidase D homolog 0.0087 0.0424 0.0765
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0014 0.0017 0.0023
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0029 0.0039
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0189 0.099 0.3474
Echinococcus granulosus transcription factor btf3 0.0035 0.0137 0.0185
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0029 0.0039
Echinococcus multilocularis thymidylate synthase 0.1002 0.5519 0.7467
Echinococcus multilocularis survival motor neuron protein 1 0.0238 0.1268 0.1716
Schistosoma mansoni cpg binding protein 0.0031 0.0111 0.015
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0082 0.0053
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0189 0.099 0.3474
Schistosoma mansoni thyroid hormone receptor 0.0014 0.0017 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0014 0.0017 0.0023
Mycobacterium ulcerans thymidylate synthase 0.1002 0.5519 0.7467
Loa Loa (eye worm) hypothetical protein 0.0238 0.1268 0.1716
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0029 0.0029
Echinococcus granulosus ecdysone induced protein 78C 0.0014 0.0017 0.0023
Brugia malayi dihydrofolate reductase family protein 0.1338 0.739 1
Echinococcus granulosus thymidylate synthase 0.1002 0.5519 0.7467
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0014 0.0017 0.0023
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0082 0.0082
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0014 0.0017 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0014 0.0017 0.0023
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0049 0.0049
Trypanosoma brucei cytochrome P450, putative 0.002 0.0049 0.0049
Brugia malayi Dihydrofolate reductase 0.1338 0.739 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0142 0.0193
Trichomonas vaginalis beta-hexosaminidase, putative 0.0234 0.1242 0.4497
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.1338 0.739 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0014 0.0017 0.0023
Loa Loa (eye worm) steroid hormone receptor 0.0014 0.0017 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0014 0.0017 0.0023
Echinococcus granulosus geminin 0.0171 0.0892 0.1207
Trichomonas vaginalis beta-hexosaminidase B, putative 0.0234 0.1242 0.4497
Leishmania major hypothetical protein, conserved 0.0058 0.0264 0.0264
Entamoeba histolytica hypothetical protein 0.0036 0.0142 0.003
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0029 0.0029
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0189 0.099 0.134
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0189 0.099 0.5
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0058 0.0264 0.0264
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0132 0.0132
Schistosoma mansoni survival motor neuron protein 0.0049 0.0211 0.0286
Leishmania major oxidoreductase-like protein 0.0011 0.0002 0.0002
Echinococcus granulosus multidrug and toxin extrusion protein 2 0.0034 0.0132 0.0179
Toxoplasma gondii NAC domain-containing protein 0.0035 0.0137 0.0137
Schistosoma mansoni coup transcription factor 0.0014 0.0017 0.0023
Brugia malayi hypothetical protein 0.0025 0.0082 0.0111
Trypanosoma brucei transcription factor BTF3, putative 0.0035 0.0137 0.0137
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0014 0.0017 0.0023
Trypanosoma brucei MATE efflux family protein, putative 0.0034 0.0132 0.0132
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0264 0.0264
Brugia malayi thymidylate synthase 0.1002 0.5519 0.7467
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0014 0.0017 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0014 0.0017 0.0023
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0082 0.0053
Echinococcus multilocularis thyroid hormone receptor alpha 0.0014 0.0017 0.0023
Echinococcus multilocularis geminin 0.0171 0.0892 0.1207
Echinococcus multilocularis beta hexosaminidase subunit alpha 0.0234 0.1242 0.168
Schistosoma mansoni hypothetical protein 0.0049 0.0211 0.0286
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0017 0.0023
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0189 0.099 0.3474
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0014 0.0017 0.0023
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.1338 0.739 1
Trichomonas vaginalis beta-hexosaminidase, putative 0.0087 0.0424 0.1169
Echinococcus granulosus tumor protein p63 0.0341 0.1837 0.2486
Onchocerca volvulus 0.0029 0.0102 0.0181
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0014 0.0017 0.0023
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.1002 0.5519 0.7467
Loa Loa (eye worm) ICD-1 protein 0.0035 0.0137 0.0185
Leishmania major hypothetical protein, conserved 0.0034 0.0132 0.0132
Mycobacterium tuberculosis Hypothetical protein 0.0477 0.2594 0.351
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0014 0.0017 0.0023
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0014 0.0017 0.0023
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0011 0.0002 0.0002
Loa Loa (eye worm) CYP4Cod1 0.002 0.0049 0.0067
Schistosoma mansoni hypothetical protein 0.0412 0.2237 0.3026
Brugia malayi ecdysteroid receptor 0.0014 0.0017 0.0023
Loa Loa (eye worm) hypothetical protein 0.0087 0.0424 0.0574
Schistosoma mansoni hypothetical protein 0.0171 0.0892 0.1207
Schistosoma mansoni cpg binding protein 0.0029 0.0102 0.0138
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0029 0.0039
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0011 0.0002 0.0002
Echinococcus multilocularis transcription factor btf3 0.0035 0.0137 0.0185
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0029 0.0039
Entamoeba histolytica beta-N-acetylhexosaminidase, putative 0.0374 0.2024 1
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.0034 0.0132 0.0179
Echinococcus multilocularis FTZ F1 alpha 0.0014 0.0017 0.0023
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0011 0.0002 0.0002
Echinococcus granulosus beta hexosaminidase subunit beta 0.0374 0.2024 0.2738
Onchocerca volvulus Bile acid receptor homolog 0.0014 0.0017 0.0028
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0017 0.0023
Brugia malayi nuclear receptor NHR-88 0.0014 0.0017 0.0023
Onchocerca volvulus 0.1002 0.5519 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0011 0.0002 0.0002
Echinococcus multilocularis dihydrofolate reductase 0.1338 0.739 1
Trypanosoma brucei membrane transporter protein, putative 0.0034 0.0132 0.0132
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0017 0.0023
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0014 0.0017 0.0023
Brugia malayi nuclear hormone receptor 0.0014 0.0017 0.0023
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0082 0.0082
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0102 0.0138
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0014 0.0017 0.0023
Schistosoma mansoni transcription factor btf3 0.0035 0.0137 0.0185
Schistosoma mansoni retinoic acid receptor RXR 0.0014 0.0017 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0014 0.0017 0.0023
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0477 0.2594 0.2594
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0014 0.0017 0.0023
Echinococcus granulosus cpg binding protein 0.0031 0.0111 0.015
Entamoeba histolytica beta-N-acetylhexosaminidase, putative 0.0374 0.2024 1
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0137 0.0137
Trypanosoma brucei membrane transporter protein, putative 0.0034 0.0132 0.0132
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0029 0.0039
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0049 0.0067
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0142 0.0193
Plasmodium vivax basic transcription factor 3b, putative 0.0035 0.0137 0.0108
Entamoeba histolytica hypothetical protein 0.0036 0.0142 0.003
Brugia malayi Steroid receptor seven-up type 2 0.0014 0.0017 0.0023
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0189 0.099 0.3474
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0017 0.0023
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0082 0.0082
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.1338 0.739 1
Brugia malayi Glycosyl hydrolase family 20, catalytic domain containing protein 0.0087 0.0424 0.0574
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0014 0.0017 0.0023
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0023
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.1002 0.5519 0.7467
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.1002 0.5519 0.7467
Entamoeba histolytica beta-N-acetylhexosaminidase, beta subunit 0.0374 0.2024 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0282 0.0382
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0023
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0029 0.0029
Brugia malayi hypothetical protein 0.0477 0.2594 0.351
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0023
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0029 0.0039
Schistosoma mansoni dihydrofolate reductase 0.1338 0.739 1
Echinococcus multilocularis Multi antimicrobial extrusion protein MatE 0.0031 0.0115 0.0156
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0029 0.0029
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0029 0.0039
Onchocerca volvulus 0.0014 0.0017 0.0028
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.013 0.0667 0.0902
Entamoeba histolytica hypothetical protein 0.0036 0.0142 0.003
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0014 0.0017 0.0028
Onchocerca volvulus Protein ultraspiracle homolog 0.0014 0.0017 0.0028
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0029 0.0039
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0017 0.0023
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0132 0.0132
Echinococcus multilocularis cpg binding protein 0.0031 0.0111 0.015
Schistosoma mansoni beta-hexosaminidase B 0.0374 0.2024 0.2738
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0246 0.0246
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0189 0.099 0.4525
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0058 0.0264 0.0518
Schistosoma mansoni cpg binding protein 0.0031 0.0111 0.015
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0264 0.0264
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0014 0.0017 0.0023
Plasmodium falciparum basic transcription factor 3b, putative 0.0035 0.0137 0.0108
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0014 0.0017 0.0023
Leishmania major hypothetical protein, conserved 0.0034 0.0132 0.0132
Brugia malayi Glycosyl hydrolase family 20, catalytic domain containing protein 0.0374 0.2024 0.2738
Schistosoma mansoni beta-hexosaminidase B 0.0374 0.2024 0.2738
Schistosoma mansoni hypothetical protein 0.0011 0.0004 0.0005
Trypanosoma brucei pteridine reductase 1 0.0196 0.1031 0.1031
Entamoeba histolytica beta-N-acetylhexosaminidase, alpha subunit 0.0374 0.2024 1
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0132 0.0132
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0211 0.0286
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0023
Echinococcus granulosus dihydrofolate reductase 0.1338 0.739 1
Schistosoma mansoni RAR-like nuclear receptor 0.0014 0.0017 0.0023
Schistosoma mansoni hypothetical protein 0.0171 0.0892 0.1207
Trichomonas vaginalis beta-hexosaminidase, putative 0.0234 0.1242 0.4497
Entamoeba histolytica hypothetical protein 0.0036 0.0142 0.003
Onchocerca volvulus 0.005 0.0218 0.0392
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0004 0.0005
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0014 0.0017 0.0023
Brugia malayi beta-NAC-like protein 0.0035 0.0137 0.0185
Loa Loa (eye worm) hypothetical protein 0.005 0.0218 0.0295
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0049 0.0067
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0014 0.0017 0.0023
Echinococcus multilocularis beta hexosaminidase subunit beta 0.0374 0.2024 0.2738
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0142 0.0193
Trypanosoma brucei oxidoreductase-like protein 0.0011 0.0002 0.0002
Echinococcus granulosus survival motor neuron protein 1 0.0238 0.1268 0.1716
Loa Loa (eye worm) hypothetical protein 0.0025 0.0082 0.0111
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0029 0.0039
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0189 0.099 0.3474
Mycobacterium ulcerans short chain dehydrogenase 0.0011 0.0002 0.0002
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0029 0.0039
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0058 0.0264 0.0518
Leishmania major hypothetical protein, conserved 0.0025 0.0082 0.0082
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0014 0.0017 0.0023
Schistosoma mansoni hypothetical protein 0.0036 0.0142 0.0193
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0029 0.0029
Echinococcus granulosus FTZ F1 alpha 0.0014 0.0017 0.0023
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0082 0.0053
Loa Loa (eye worm) thymidylate synthase 0.1002 0.5519 0.7467
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0014 0.0017 0.0023
Brugia malayi hypothetical protein 0.0036 0.0142 0.0193
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0014 0.0017 0.0023
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.002 0.0049 0.0067
Brugia malayi isocitrate dehydrogenase 0.0016 0.0029 0.0039
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0049 0.0049
Leishmania major pteridine reductase 1 0.0199 0.1046 0.1046
Brugia malayi steroid hormone receptor 0.0014 0.0017 0.0023
Chlamydia trachomatis dihydrofolate reductase 0.1338 0.739 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0477 0.2594 1
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0189 0.099 0.3474
Loa Loa (eye worm) dihydrofolate reductase 0.1338 0.739 1
Brugia malayi Glycosyl hydrolase family 20, catalytic domain containing protein 0.0087 0.0424 0.0574
Loa Loa (eye worm) hypothetical protein 0.0014 0.0017 0.0023
Schistosoma mansoni steroid hormone receptor ad4bp 0.0014 0.0017 0.0023
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0189 0.099 0.4525
Brugia malayi Cytochrome P450 family protein 0.002 0.0049 0.0067
Mycobacterium tuberculosis Probable oxidoreductase 0.0011 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0052 0.0231 0.0312
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0014 0.0017 0.0023
Echinococcus granulosus beta hexosaminidase subunit alpha 0.0234 0.1242 0.168
Trypanosoma cruzi membrane transporter protein, putative 0.0034 0.0132 0.0132
Onchocerca volvulus 0.0189 0.099 0.1792
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0014 0.0017 0.0023
Echinococcus granulosus dnaJ subfamily B 0.0412 0.2237 0.3026
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0029 0.0029

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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