Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Decrease (functional) | = -30.6 % | The hypoglycemic activity in diabetic KK mice,activity expressed as % decrease in blood glucose (18 h) | ChEMBL. | 10956213 |
Decrease (functional) | = -3.2 % | The hypoglycemic activity in diabetic KK mice,activity expressed as % decrease in blood glucose (21h) | ChEMBL. | 10956213 |
EC (functional) | = 1.98 uM | Stimulation of adipogenesis in 3T3-L1 cells is expressed as concentration equivalent to the [ 1-14C] uptake counts after treatment with 0.2 ug/mL troglitazone | ChEMBL. | 10956213 |
EC (functional) | = 1.98 uM | Stimulation of adipogenesis in 3T3-L1 cells is expressed as concentration equivalent to the [ 1-14C] uptake counts after treatment with 0.2 ug/mL troglitazone | ChEMBL. | 10956213 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.