Detailed information for compound 1730836

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 250.333 | Formula: C15H22O3
  • H donors: 1 H acceptors: 2 LogP: 2.19 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: O[C@H]1C[C@H](C)[C@@]2(C(=C1)C[C@@H]1[C@H](C2)[C@H](C(=O)O1)C)C
  • InChi: 1S/C15H22O3/c1-8-4-11(16)5-10-6-13-12(7-15(8,10)3)9(2)14(17)18-13/h5,8-9,11-13,16H,4,6-7H2,1-3H3/t8-,9+,11-,12+,13+,15+/m0/s1
  • InChiKey: XZQRUWPDGTZJEB-ROTUKVCOSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0045 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Schistosoma mansoni hypothetical protein 0.0047 0.02 0.0236
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0186 0.0742
Mycobacterium tuberculosis Probable hydrolase 0.0072 0.0351 0.1117
Loa Loa (eye worm) uncoordinated protein 58 0.0037 0.0137 0.0224
Brugia malayi RNA binding protein 0.0062 0.0293 0.0542
Leishmania major hypothetical protein, conserved 0.0037 0.0137 0.1632
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0318 0.0519
Schistosoma mansoni alkaline phosphatase 0.016 0.0906 0.1066
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0092 0.015
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0092 0.0108
Trichomonas vaginalis endoplasmin, putative 0.0033 0.0112 0.0347
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.015
Entamoeba histolytica acyl-coA synthetase, putative 0.0047 0.0198 0.0631
Brugia malayi Niemann-Pick C1 protein precursor 0.0196 0.1129 0.2083
Toxoplasma gondii sugar transporter ST2 0.0045 0.0186 0.0671
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Trypanosoma cruzi heat shock protein, putative 0.0031 0.0094 0.1406
Trichomonas vaginalis conserved hypothetical protein 0.0321 0.1914 1
Schistosoma mansoni inositol monophosphatase 0.0036 0.0131 0.0154
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0067 0.0321 0.0321
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0091 0.016
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0092 0.015
Trypanosoma brucei glucose transporter 1E 0.01 0.0526 1
Schistosoma mansoni hypothetical protein 0.0063 0.0297 0.0349
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0005
Echinococcus multilocularis synaptic vesicle 2 protein 0.0045 0.0186 0.0186
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0021 0.0032 0.018
Loa Loa (eye worm) hypothetical protein 0.0072 0.0351 0.0573
Trichomonas vaginalis conserved hypothetical protein 0.01 0.0526 0.2568
Echinococcus granulosus zinc finger protein 0.0041 0.0157 0.0184
Brugia malayi intermediate filament protein 0.0027 0.0072 0.0133
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.174 0.9066
Trypanosoma brucei heat shock protein, putative 0.0046 0.0191 0.2784
Brugia malayi hypothetical protein 0.0123 0.0673 0.1242
Toxoplasma gondii ABC1 family protein 0.0072 0.0351 0.1565
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0092 0.017
Schistosoma mansoni lozenge 0.011 0.0595 0.07
Onchocerca volvulus 0.0045 0.0186 0.0295
Schistosoma mansoni intermediate filament proteins 0.0027 0.0072 0.0085
Echinococcus granulosus FTZ F1 alpha 0.003 0.0092 0.0108
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.019 0.0224
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0129 0.0152
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Loa Loa (eye worm) sugar transporter 0.0045 0.0186 0.0303
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0039 0.0149 0.0175
Mycobacterium ulcerans hypothetical protein 0.0072 0.0351 0.3365
Entamoeba histolytica hypothetical protein 0.0035 0.0122 0.0173
Echinococcus multilocularis solute carrier family 22 0.0045 0.0186 0.0186
Loa Loa (eye worm) runx1 0.011 0.0595 0.0971
Treponema pallidum glyceraldehyde 3-phosphate dehydrogenase (gap) 0.0067 0.0321 0.0945
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.016 0.0906 0.1066
Trypanosoma brucei THT1 - hexose transporter, putative 0.01 0.0526 1
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0037 0.0137 0.0224
Schistosoma mansoni calcium-activated potassium channel 0.0037 0.0137 0.0161
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, cytosolic 0.0067 0.0321 0.5587
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0071 0.035 0.0412
Brugia malayi beta-lactamase family protein 0.0072 0.0351 0.0648
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Onchocerca volvulus Putative transporter 0.0045 0.0186 0.0295
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0045 0.0186 0.2673
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Mycobacterium leprae Probable lipase LipE 0.0072 0.0351 0.4036
Echinococcus granulosus geminin 0.017 0.0968 0.1139
Echinococcus multilocularis sterol regulatory element binding protein 0.0084 0.0429 0.0429
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0107 0.0218
Schistosoma mansoni twik family of potassium channels-related 0.0037 0.0137 0.0161
Leishmania major basic transcription factor 3a, putative 0.0035 0.0122 0.1318
Echinococcus multilocularis RUN 0.002 0.0027 0.0027
Echinococcus granulosus twik family of potassium channels 0.0037 0.0137 0.0161
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0046 0.0191 0.0313
Echinococcus multilocularis potassium channel subfamily K 8 0.0037 0.0137 0.0137
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.019 0.0311
Schistosoma mansoni hypothetical protein 0.0081 0.041 0.0482
Schistosoma mansoni lipoxygenase 0.0083 0.0421 0.0495
Trypanosoma brucei calcium-activated potassium channel, putative 0.0037 0.0137 0.1632
Brugia malayi PHD-finger family protein 0.0051 0.0223 0.0412
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0092 0.0092
Trypanosoma cruzi heat shock protein 90, putative 0.0039 0.0149 0.25
Schistosoma mansoni smad 0.0016 0.0004 0.0005
Echinococcus granulosus RUN 0.002 0.0027 0.0031
Entamoeba histolytica heat shock protein 90, putative 0.0046 0.0191 0.0587
Trypanosoma cruzi heat shock protein 85, putative 0.0046 0.0191 0.3327
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0457 0.2767 1
Schistosoma mansoni sugar transporter 0.0045 0.0186 0.0218
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0092 0.0108
Trichomonas vaginalis glucose transporter, putative 0.0045 0.0186 0.0742
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.019 0.0224
Schistosoma mansoni glucose transporter 0.0045 0.0186 0.0218
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.015
Brugia malayi CHE-14 protein 0.0084 0.0429 0.0791
Toxoplasma gondii transporter, major facilitator family protein 0.0045 0.0186 0.0671
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0099 0.0099
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0131 0.0154
Echinococcus multilocularis lamin 0.0027 0.0072 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0186 0.0742
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0351 0.6514
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0092 0.0108
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.015
Loa Loa (eye worm) hypothetical protein 0.0045 0.0186 0.0303
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0092 0.0108
Loa Loa (eye worm) hypothetical protein 0.0035 0.0123 0.0201
Entamoeba histolytica hypothetical protein 0.0036 0.0129 0.0211
Echinococcus granulosus heat shock protein 90 0.0039 0.0149 0.0175
Loa Loa (eye worm) heat shock protein 90 0.0046 0.0191 0.0311
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Echinococcus granulosus survival motor neuron protein 1 0.0233 0.1361 0.1602
Trypanosoma brucei glucose transporter, putative 0.01 0.0526 1
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0067 0.0321 0.1468
Toxoplasma gondii Hsp90 domain-containing protein 0.0174 0.0994 0.5035
Entamoeba histolytica hypothetical protein 0.0036 0.0129 0.0211
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0067 0.0321 0.1468
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0072 0.0351 0.0573
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0198 0.0631
Mycobacterium tuberculosis Probable lipase LipE 0.0072 0.0351 0.1117
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0037 0.0137 0.0253
Brugia malayi Bromodomain containing protein 0.0076 0.038 0.0701
Echinococcus granulosus solute carrier family 22 0.0045 0.0186 0.0218
Giardia lamblia Hexose transporter 0.0045 0.0186 0.0302
Plasmodium vivax endoplasmin, putative 0.0046 0.0191 0.0869
Echinococcus multilocularis dnaJ subfamily B 0.0402 0.2425 0.2425
Loa Loa (eye worm) hypothetical protein 0.0084 0.0429 0.07
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0099 0.0823
Onchocerca volvulus 0.0072 0.0351 0.0602
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0293 0.174 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.174 0.9066
Schistosoma mansoni twik family of potassium channels-related 0.0037 0.0137 0.0161
Echinococcus granulosus heat shock protein 90 0.0046 0.0191 0.0224
Schistosoma mansoni transcription factor btf3 0.0035 0.0122 0.0144
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0092 0.0108
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0037 0.0137 0.2261
Onchocerca volvulus 0.0037 0.0137 0.0205
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0143 0.08 1
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.016 0.0906 0.1066
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0137 0.0483
Leishmania major glucose transporter/membrane transporter D2, putative 0.01 0.0526 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0092 0.015
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0293 0.0345
Schistosoma mansoni heat shock protein 0.0031 0.0094 0.0111
Onchocerca volvulus 0.0045 0.0186 0.0295
Loa Loa (eye worm) hypothetical protein 0.0045 0.0186 0.0303
Trypanosoma cruzi ion transport protein, putative 0.0037 0.0137 0.2261
Echinococcus multilocularis Protein lozenge 0.011 0.0595 0.0595
Echinococcus multilocularis smad 0.0016 0.0004 0.0004
Brugia malayi hypothetical protein 0.0016 0.0005 0.0009
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Trichomonas vaginalis heat shock protein, putative 0.0043 0.0173 0.0675
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0037 0.0137 0.0253
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0037 0.0137 0.0253
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0092 0.017
Echinococcus granulosus General substrate transporter 0.0276 0.1631 0.192
Loa Loa (eye worm) hypothetical protein 0.0099 0.0526 0.0859
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0137 0.0483
Loa Loa (eye worm) hypothetical protein 0.0233 0.1361 0.2222
Echinococcus multilocularis solute carrier family 22 0.0045 0.0186 0.0186
Echinococcus multilocularis Ankyrin 0.0063 0.0298 0.0298
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0099 0.0207
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0027 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0092 0.017
Brugia malayi hypothetical protein 0.0037 0.0137 0.0253
Schistosoma mansoni twik family of potassium channels-related 0.0037 0.0137 0.0161
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Mycobacterium leprae conserved hypothetical protein 0.0072 0.0351 0.4036
Mycobacterium ulcerans lipase LipD 0.0072 0.0351 0.3365
Schistosoma mansoni smad1 5 8 and 0.0016 0.0004 0.0005
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0122 0.1971
Leishmania major heat shock protein 83-1 0.0046 0.0191 0.2784
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0092 0.017
Onchocerca volvulus 0.0045 0.0186 0.0295
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0045 0.0186 0.0919
Leishmania major hypothetical protein, conserved 0.0072 0.0351 0.623
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0175 0.0997 0.1839
Onchocerca volvulus 0.0045 0.0186 0.0295
Trypanosoma cruzi hexose transporter, putative 0.0054 0.0244 0.438
Loa Loa (eye worm) hypothetical protein 0.002 0.0027 0.0043
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0004 0.0004
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0198 0.1103
Schistosoma mansoni calcium-activated potassium channel 0.0993 0.6124 0.7209
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0037 0.0137 0.0253
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Onchocerca volvulus 0.0037 0.0137 0.0205
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0318 0.5849
Schistosoma mansoni patched 1 0.0084 0.0429 0.0505
Onchocerca volvulus 0.0045 0.0186 0.0295
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0131 0.0222
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0037 0.0137 0.033
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0045 0.0186 0.0508
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0129 0.0129
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Trypanosoma brucei glucose transporter, putative 0.01 0.0526 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.021 0.0343
Giardia lamblia Heat shock protein HSP 90-alpha 0.0046 0.0191 0.0335
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0099 0.0386
Onchocerca volvulus 0.088 0.5418 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0237 0.1389 0.2268
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0037 0.0137 0.0253
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0072 0.0351 0.0648
Plasmodium vivax heat shock protein, putative 0.0174 0.0994 0.5126
Trypanosoma brucei heat shock protein, putative 0.0046 0.0191 0.2784
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0092 0.0108
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.021 0.0388
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0186 0.0742
Leishmania major heat shock protein 83-1 0.0046 0.0191 0.2784
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Loa Loa (eye worm) hypothetical protein 0.0034 0.0113 0.0184
Trichomonas vaginalis sugar transport protein, putative 0.0045 0.0186 0.0742
Echinococcus granulosus solute carrier family 22 0.0045 0.0186 0.0218
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0004 0.0005
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0099 0.0162
Onchocerca volvulus 0.0045 0.0186 0.0295
Loa Loa (eye worm) hypothetical protein 0.0045 0.0186 0.0303
Loa Loa (eye worm) hypothetical protein 0.0045 0.0186 0.0303
Brugia malayi Major Facilitator Superfamily protein 0.0045 0.0186 0.0342
Plasmodium falciparum heat shock protein 90, putative 0.0174 0.0994 0.5126
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.019 0.019
Schistosoma mansoni hypothetical protein 0.002 0.0027 0.0031
Echinococcus multilocularis expressed conserved protein 0.0184 0.1054 0.1054
Echinococcus granulosus fetal alzheimer antigen falz 0.0046 0.0194 0.0228
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0092 0.015
Onchocerca volvulus 0.0037 0.0137 0.0205
Echinococcus granulosus tar DNA binding protein 0.0062 0.0293 0.0345
Loa Loa (eye worm) bromodomain containing protein 0.0035 0.0123 0.02
Loa Loa (eye worm) hypothetical protein 0.0047 0.0198 0.0323
Loa Loa (eye worm) hypothetical protein 0.0072 0.0351 0.0573
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0063 0.0297 0.0297
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.0351 0.623
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0293 0.174 1
Schistosoma mansoni rab6-interacting 0.002 0.0027 0.0031
Toxoplasma gondii facilitative glucose transporter GT1 0.0321 0.1914 1
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0318 0.0374
Mycobacterium ulcerans glyceraldehyde 3-phosphate dehydrogenase Gap 0.0067 0.0321 0.2923
Schistosoma mansoni hypothetical protein 0.003 0.0093 0.011
Schistosoma mansoni smad1 5 8 and 0.0016 0.0004 0.0005
Echinococcus multilocularis General substrate transporter 0.0276 0.1631 0.1631
Schistosoma mansoni hypothetical protein 0.0321 0.1914 0.2253
Echinococcus multilocularis microtubule associated protein 2 0.1371 0.8496 0.8496
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0351 0.1629
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0067 0.0321 0.5587
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0131 0.0447
Onchocerca volvulus 0.0037 0.0137 0.0205
Echinococcus granulosus twik family of potassium channels 0.0037 0.0137 0.0161
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.015
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0067 0.0321 0.5918
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.0149 0.25
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0005
Echinococcus granulosus neuropeptide s receptor 0.0471 0.2854 0.3359
Echinococcus granulosus intestinal type alkaline phosphatase 0.016 0.0906 0.1066
Schistosoma mansoni polycystin 1-related 0.002 0.0027 0.0031
Onchocerca volvulus 0.0072 0.0351 0.0602
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0092 0.0092
Mycobacterium ulcerans sugar transporter 0.0045 0.0186 0.0919
Leishmania major glyceraldehyde-3-phosphate dehydrogenase-like protein 0.0044 0.0177 0.2481
Onchocerca volvulus 0.003 0.0091 0.0119
Trypanosoma brucei glucose transporter, putative 0.01 0.0526 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Echinococcus multilocularis beta LACTamase domain containing family member 0.0072 0.0351 0.0351
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0067 0.0321 0.138
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0198 0.1103
Trichomonas vaginalis glucose transporter, putative 0.01 0.0526 0.2568
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0131 0.2131
Schistosoma mansoni hypothetical protein 0.0083 0.0424 0.0499
Echinococcus granulosus heat shock protein 0.0046 0.0191 0.0224
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0293 0.0345
Leishmania major hypothetical protein, conserved 0.0037 0.0137 0.1632
Brugia malayi hypothetical protein 0.0016 0.0003 0.0005
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0099 0.1514
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0321 0.1914 0.2253
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0099 0.0099
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0047 0.0198 0.1103
Plasmodium falciparum potassium channel 0.0037 0.0137 0.0585
Schistosoma mansoni hypothetical protein 0.0037 0.0137 0.0161
Schistosoma mansoni ankyrin 23/unc44 0.0063 0.0297 0.0349
Brugia malayi major facilitator superfamily protein 0.0045 0.0186 0.0342
Schistosoma mansoni heat shock protein 0.0046 0.0191 0.0224
Onchocerca volvulus 0.0045 0.0186 0.0295
Brugia malayi Pre-SET motif family protein 0.003 0.0091 0.0167
Brugia malayi hypothetical protein 0.088 0.5418 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0137 0.0483
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0198 0.0631
Loa Loa (eye worm) hypothetical protein 0.0103 0.0547 0.0893
Schistosoma mansoni survival motor neuron protein 0.0047 0.02 0.0236
Echinococcus granulosus Sugar transporter ERD6 protein 0.0045 0.0186 0.0218
Loa Loa (eye worm) heat shock protein 75 0.0031 0.0094 0.0154
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.019 0.0224
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.02 0.0369
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0351 0.1629
Loa Loa (eye worm) hypothetical protein 0.0063 0.0297 0.0484
Plasmodium vivax potassium channel, putative 0.0037 0.0137 0.0585
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0021 0.0032 0.018
Trichomonas vaginalis heat shock protein, putative 0.0033 0.0112 0.0347
Echinococcus multilocularis endoplasmin 0.0043 0.0173 0.0173
Schistosoma mansoni heat shock protein 0.0046 0.0191 0.0224
Schistosoma mansoni sugar transporter 0.0045 0.0186 0.0218
Schistosoma mansoni loxhd1 0.002 0.0027 0.0031
Brugia malayi major facilitator superfamily protein 0.0045 0.0186 0.0342
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0023 0.0047 0.0087
Trypanosoma cruzi ISWI complex protein 0.003 0.0093 0.139
Loa Loa (eye worm) hypothetical protein 0.0045 0.0186 0.0303
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0131 0.1491
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0067 0.0321 0.0378
Trypanosoma cruzi hexose transporter 0.01 0.0526 1
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0107 0.0789
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Echinococcus granulosus lamin 0.0027 0.0072 0.0085
Loa Loa (eye worm) hypothetical protein 0.0027 0.0069 0.0113
Trypanosoma brucei glucose transporter, putative 0.01 0.0526 1
Onchocerca volvulus 0.0045 0.0186 0.0295
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0186 0.0742
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0293 0.0479
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0321 0.1914 0.1914
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.174 0.9066
Brugia malayi hypothetical protein 0.002 0.0027 0.0049
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0067 0.0321 0.0321
Trypanosoma cruzi hexose transporter, putative 0.01 0.0526 1
Schistosoma mansoni hypothetical protein 0.0034 0.0113 0.0133
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0027 0.0027
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.019 0.0224
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Loa Loa (eye worm) major facilitator superfamily transporter 0.0045 0.0186 0.0303
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0092 0.017
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.008 0.013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0092 0.015
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0067 0.0321 0.0378
Loa Loa (eye worm) hypothetical protein 0.0072 0.0351 0.0573
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0198 0.0365
Trichomonas vaginalis set domain proteins, putative 0.0234 0.1367 0.7073
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0037 0.0137 0.0224
Schistosoma mansoni twik family of potassium channels-related 0.0037 0.0137 0.0161
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0021 0.0032 0.018
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0067 0.0321 0.5918
Brugia malayi hypothetical protein 0.0016 0.0003 0.0005
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0099 0.0099
Trypanosoma brucei glucose transporter, putative 0.01 0.0526 1
Echinococcus multilocularis heat shock protein 90 0.0039 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0045 0.0186 0.0303
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0031 0.0094 0.0111
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0021 0.0032 0.018
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0037 0.0137 0.0253
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Brugia malayi Pre-SET motif family protein 0.0205 0.119 0.2197
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0092 0.0092
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0067 0.0321 0.1468
Trichomonas vaginalis conserved hypothetical protein 0.01 0.0526 0.2568
Echinococcus multilocularis transcription factor btf3 0.0035 0.0122 0.0122
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Plasmodium vivax glyceraldehyde-3-phosphate dehydrogenase, putative 0.0067 0.0321 0.156
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0067 0.0321 0.1468
Brugia malayi steroid hormone receptor 0.003 0.0092 0.017
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0137 0.2261
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0122 0.0404
Echinococcus granulosus transcription factor btf3 0.0035 0.0122 0.0144
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0027 0.0031
Echinococcus multilocularis tumor protein p63 0.0339 0.2026 0.2026
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0092 0.0108
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0091 0.0091
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Brugia malayi MH2 domain containing protein 0.0237 0.1389 0.2564
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Loa Loa (eye worm) hypothetical protein 0.0044 0.0177 0.0289
Trypanosoma brucei glucose transporter, putative 0.01 0.0526 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0092 0.017
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0092 0.017
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0123 0.0512
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0045 0.0186 0.0508
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0043 0.0173 0.2404
Loa Loa (eye worm) doublecortin family protein 0.002 0.0027 0.0043
Trypanosoma brucei ISWI complex protein 0.003 0.0093 0.069
Echinococcus granulosus potassium channel subfamily K 0.0037 0.0137 0.0161
Leishmania major heat shock protein 83-1 0.0046 0.0191 0.2784
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0061 0.0183
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0061 0.0183
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0063 0.0297 0.0349
Brugia malayi hypothetical protein 0.002 0.0027 0.0049
Leishmania major heat shock protein 83-1 0.0046 0.0191 0.2784
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0067 0.0321 0.0378
Loa Loa (eye worm) hypothetical protein 0.0076 0.038 0.0621
Echinococcus granulosus lamin dm0 0.0027 0.0072 0.0085
Loa Loa (eye worm) hypothetical protein 0.0045 0.0186 0.0303
Loa Loa (eye worm) hypothetical protein 0.005 0.0214 0.0349
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0067 0.0321 0.1148
Trypanosoma brucei Heat shock protein 83, putative 0.0046 0.0191 0.2784
Loa Loa (eye worm) hypothetical protein 0.0035 0.0123 0.0201
Trypanosoma cruzi hexose transporter, putative 0.01 0.0526 1
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0351 0.1629
Loa Loa (eye worm) hypothetical protein 0.0045 0.0186 0.0303
Leishmania major heat shock protein 83-1 0.0046 0.0191 0.2784
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0067 0.0321 0.0378
Loa Loa (eye worm) major facilitator superfamily transporter 0.0045 0.0186 0.0303
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0047 0.0198 0.1103
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.019 0.0224
Giardia lamblia Heat shock protein HSP 90-alpha 0.0039 0.0149 0.0075
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0037 0.0137 0.0161
Schistosoma mansoni methyl-cpg binding protein mbd 0.0206 0.1194 0.1405
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0037 0.0137 0.0161
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.174 0.9066
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0321 0.1914 0.2253
Entamoeba histolytica heat shock protein 90, putative 0.0046 0.0191 0.0587
Loa Loa (eye worm) hypothetical protein 0.0123 0.0673 0.1098
Echinococcus multilocularis twik family of potassium channels 0.0037 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0035 0.0123 0.0201
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0067 0.0321 0.5587
Loa Loa (eye worm) hypothetical protein 0.0045 0.0186 0.0303
Echinococcus multilocularis Smad4 0.0016 0.0004 0.0004
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0111 0.0235
Loa Loa (eye worm) hypothetical protein 0.0123 0.0673 0.1098
Echinococcus granulosus histone lysine methyltransferase setb 0.0139 0.0776 0.0913
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0351 0.6514
Echinococcus granulosus smad 0.0016 0.0004 0.0005
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0321 0.1914 0.1914
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0044 0.0177 0.0695
Trichomonas vaginalis conserved hypothetical protein 0.017 0.0967 0.4926
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.019 0.019
Trypanosoma brucei heat shock protein 90, putative 0.0046 0.0191 0.2784
Schistosoma mansoni twik family of potassium channels-related 0.0037 0.0137 0.0161
Brugia malayi Protein kinase domain containing protein 0.0063 0.0297 0.0547
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0063 0.0298 0.0351
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0072 0.0351 0.1117
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0092 0.017
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0196 0.1129 0.6288
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0063 0.0297 0.0484
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0027 0.0031
Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase, putative 0.0044 0.0177 0.2481
Schistosoma mansoni thyroid hormone receptor 0.003 0.0092 0.0108
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH1 0.0067 0.0321 0.1403
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.174 0.9066
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0285 0.0336
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Trypanosoma brucei heat shock protein, putative 0.0046 0.0191 0.2784
Schistosoma mansoni cpg binding protein 0.0034 0.0114 0.0134
Brugia malayi isocitrate dehydrogenase 0.0031 0.0099 0.0184
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0037 0.0137 0.0253
Leishmania major calcium/potassium channel (CAKC), putative 0.0037 0.0137 0.1632
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0047 0.0198 0.0554
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0129 0.0152
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0293 0.0479
Trypanosoma brucei heat shock protein 90, putative 0.0046 0.0191 0.2784
Leishmania major heat shock protein 83-1 0.0046 0.0191 0.2784
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0092 0.015
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0046 0.0191 0.0313
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0037 0.0137 0.0253
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0092 0.015
Echinococcus multilocularis geminin 0.017 0.0968 0.0968
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0092 0.0121
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.015
Plasmodium vivax hypothetical protein, conserved 0.0072 0.0351 0.1719
Schistosoma mansoni hypothetical protein 0.017 0.0968 0.1139
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0131 0.1491
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0198 0.294
Leishmania major heat shock protein 83-1 0.0046 0.0191 0.2784
Onchocerca volvulus Huntingtin homolog 0.0123 0.0673 0.1198
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Toxoplasma gondii ion channel protein 0.0037 0.0137 0.041
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0031 0.0094 0.0125
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0003 0.0005
Trypanosoma cruzi heat shock protein 90, putative 0.0046 0.0191 0.3327
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Echinococcus granulosus netrin receptor unc 5 0.0063 0.0297 0.0349
Trichomonas vaginalis glucose transporter, putative 0.01 0.0526 0.2568
Brugia malayi hypothetical protein 0.0045 0.0186 0.0342
Trichomonas vaginalis heat shock protein, putative 0.0039 0.0149 0.0547
Entamoeba histolytica heat shock transcription factor, putative 0.0099 0.0526 0.2624
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0003 0.0003
Echinococcus granulosus potassium channel subfamily K 8 0.0037 0.0137 0.0161
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0072 0.0118
Schistosoma mansoni glucose transport protein 0.0321 0.1914 0.2253
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0099 0.1514
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0099 0.0099
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0092 0.0108
Loa Loa (eye worm) sugar transporter 0.0321 0.1914 0.3125
Trypanosoma cruzi heat shock protein 85, putative 0.0046 0.0191 0.3327
Schistosoma mansoni twik family of potassium channels-related 0.0037 0.0137 0.0161
Entamoeba histolytica heat shock transcription factor, putative 0.0099 0.0526 0.2624
Trichomonas vaginalis sugar transporter, putative 0.01 0.0526 0.2568
Entamoeba histolytica hypothetical protein 0.0036 0.0129 0.0211
Giardia lamblia Sugar-proton symporter 0.0045 0.0186 0.0302
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0037 0.0137 0.0253
Mycobacterium tuberculosis Probable esterase LipL 0.0072 0.0351 0.1117
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0067 0.0321 0.5918
Schistosoma mansoni endoplasmin 0.0046 0.0191 0.0224
Loa Loa (eye worm) hypothetical protein 0.0139 0.0776 0.1266
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0047 0.0198 0.1103
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0084 0.0429 0.07
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0044 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0047 0.0198 0.0323
Mycobacterium ulcerans heat shock protein 90 0.0043 0.0173 0.0734
Echinococcus granulosus endoplasmin 0.0043 0.0173 0.0204
Schistosoma mansoni endoplasmin 0.0046 0.0191 0.0224
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0351 0.1629
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0061 0.0752
Onchocerca volvulus 0.005 0.0214 0.0347
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0061 0.0183
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0067 0.0321 0.5918
Echinococcus multilocularis netrin receptor unc 5 0.0063 0.0297 0.0297
Schistosoma mansoni hypothetical protein 0.0041 0.016 0.0188
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Brugia malayi hypothetical protein 0.0025 0.0061 0.0113
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0118 0.0644 0.0758
Trypanosoma cruzi ion transport protein, putative 0.0037 0.0137 0.2261
Trypanosoma cruzi sugar transporter, putative 0.0045 0.0186 0.3224
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0092 0.0108
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0099 0.0117
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0044 0.0177 0.0247
Loa Loa (eye worm) hypothetical protein 0.0072 0.0351 0.0573
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0071 0.035 0.035
Loa Loa (eye worm) hypothetical protein 0.0025 0.0061 0.01
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0067 0.0321 0.0593
Loa Loa (eye worm) inositol-1 0.0036 0.0131 0.0213
Mycobacterium tuberculosis Conserved protein 0.0072 0.0351 0.1117
Schistosoma mansoni lamin 0.0027 0.0072 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0186 0.0742
Brugia malayi Hsp90 protein 0.0031 0.0094 0.0174
Loa Loa (eye worm) hypothetical protein 0.0072 0.0351 0.0573
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0123 0.028
Brugia malayi MH1 domain containing protein 0.0016 0.0004 0.0007
Schistosoma mansoni hypothetical protein 0.0993 0.6124 0.7209
Toxoplasma gondii sugar transporter ST3 0.0045 0.0186 0.0671
Schistosoma mansoni calcium-activated potassium channel 0.0037 0.0137 0.0161
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0067 0.0321 0.1468
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0293 0.0345
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0099 0.0099
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0321 0.1914 0.1914
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Plasmodium vivax sugar transporter, putative 0.0045 0.0186 0.0842
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0044 0.0177 0.0695
Echinococcus granulosus microtubule associated protein 2 0.1371 0.8496 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0131 0.2131
Loa Loa (eye worm) Smad1 0.0016 0.0004 0.0007
Toxoplasma gondii heat shock protein HSP90 0.0046 0.0191 0.0699
Loa Loa (eye worm) hypothetical protein 0.0081 0.041 0.0669
Echinococcus multilocularis twik family of potassium channels 0.0037 0.0137 0.0137
Brugia malayi heat shock protein 90 0.0046 0.0191 0.0352
Echinococcus granulosus cpg binding protein 0.0034 0.0114 0.0134
Echinococcus granulosus methyl CpG binding domain protein 2 0.0206 0.1194 0.1405
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0091 0.0107
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0198 0.2002
Giardia lamblia Fructose-bisphosphate aldolase 0.0293 0.174 1
Brugia malayi CXXC zinc finger family protein 0.0028 0.008 0.0147
Onchocerca volvulus 0.0037 0.0137 0.0205
Echinococcus granulosus synaptic vesicle 2 protein 0.0045 0.0186 0.0218
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0099 0.0823
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0318 0.0374
Loa Loa (eye worm) MBD3 protein 0.0145 0.0813 0.1328
Brugia malayi ecdysteroid receptor 0.003 0.0092 0.017
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0003 0.0005
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH2 0.0067 0.0321 0.1403
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Loa Loa (eye worm) hypothetical protein 0.0384 0.2313 0.3776
Echinococcus multilocularis zinc finger protein 0.0041 0.0157 0.0157
Leishmania major heat shock protein 83-1 0.0046 0.0191 0.2784
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0004 0.0004
Schistosoma mansoni inositol monophosphatase 0.0036 0.0131 0.0154
Mycobacterium tuberculosis Conserved protein 0.0072 0.0351 0.1117
Trypanosoma cruzi Heat shock protein 83, putative 0.0046 0.0191 0.3327
Trypanosoma brucei glucose transporter, putative 0.01 0.0526 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0293 0.0345
Loa Loa (eye worm) hypothetical protein 0.0027 0.0072 0.0118
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0111 0.0235
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0092 0.017
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Echinococcus multilocularis neuropeptide receptor A26 0.0471 0.2854 0.2854
Loa Loa (eye worm) hypothetical protein 0.088 0.5418 0.8847
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0092 0.0108
Echinococcus granulosus Niemann Pick C1 protein 0.0196 0.1129 0.1329
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0175 0.0997 0.1627
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Plasmodium vivax SET domain protein, putative 0.003 0.0091 0.0339
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0043 0.0173 0.0462
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0206 0.1194 0.1194
Echinococcus multilocularis protein dispatched 1 0.0096 0.0503 0.0503
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0044 0.0177 0.3047
Echinococcus granulosus potassium channel subfamily K 8 0.0037 0.0137 0.0161
Schistosoma mansoni bromodomain containing protein 0.0127 0.0701 0.0825
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0318 0.0586
Schistosoma mansoni hypothetical protein 0.0081 0.041 0.0482
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Plasmodium falciparum endoplasmin, putative 0.0033 0.0112 0.0451
Plasmodium vivax hexose transporter 0.0321 0.1914 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0072 0.0351 0.1117
Brugia malayi Immunoglobulin I-set domain containing protein 0.0063 0.0297 0.0547
Mycobacterium ulcerans beta-lactamase 0.0072 0.0351 0.3365
Trypanosoma brucei glucose transporter 2A 0.01 0.0526 1
Trypanosoma brucei heat shock protein, putative 0.0046 0.0191 0.2784
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.016 0.0906 0.0906
Plasmodium falciparum hexose transporter 0.0321 0.1914 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0198 0.294
Schistosoma mansoni Smad4 0.0016 0.0004 0.0005
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0067 0.0321 0.0378
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.015
Entamoeba histolytica heat shock transcription factor, putative 0.0099 0.0526 0.2624
Trichomonas vaginalis myo-inositol transporter, putative 0.0045 0.0186 0.0742
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0092 0.0108
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0198 0.294
Onchocerca volvulus 0.0045 0.0186 0.0295
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0429 0.2045
Echinococcus multilocularis musashi 0.0027 0.0072 0.0072
Brugia malayi MBD3 protein 0.0145 0.0813 0.1501
Schistosoma mansoni glucose transport protein 0.0321 0.1914 0.2253
Brugia malayi hypothetical protein 0.0233 0.1361 0.2512
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0031 0.0094 0.0094
Echinococcus granulosus Ankyrin 0.0063 0.0298 0.0351
Trichomonas vaginalis sugar transporter, putative 0.01 0.0526 0.2568
Schistosoma mansoni cpg binding protein 0.0034 0.0114 0.0134
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0067 0.0321 0.5918
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0037 0.0137 0.0253
Mycobacterium ulcerans esterase/lipase LipP 0.0072 0.0351 0.3365
Loa Loa (eye worm) hypothetical protein 0.0267 0.1576 0.2573
Loa Loa (eye worm) hypothetical protein 0.0035 0.0123 0.0201
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0004 0.0007
Leishmania major hypothetical protein, conserved 0.0045 0.0186 0.2673
Wolbachia endosymbiont of Brugia malayi glyceraldehyde-3-phosphate dehydrogenase, GapA 0.0067 0.0321 1
Schistosoma mansoni lamin 0.0027 0.0072 0.0085
Schistosoma mansoni alkaline phosphatase 0.016 0.0906 0.1066
Echinococcus granulosus neuropeptide receptor A26 0.0471 0.2854 0.3359
Leishmania major heat shock protein, putative 0.0031 0.0094 0.0707
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0067 0.0321 0.0378
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.174 0.9066
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0137 0.2261
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0045 0.0186 0.0919
Schistosoma mansoni calcium-activated potassium channel 0.0592 0.361 0.425
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0122 0.0404
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0092 0.017
Echinococcus granulosus alkaline phosphatase 0.016 0.0906 0.1066
Brugia malayi Doublecortin family protein 0.002 0.0027 0.0049
Leishmania major myo-inositol/proton symporter (MIT) 0.0045 0.0186 0.2673
Loa Loa (eye worm) hypothetical protein 0.002 0.0027 0.0043
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0139 0.0776 0.0913
Schistosoma mansoni thyroid hormone receptor 0.003 0.0092 0.0108
Brugia malayi Smad1 0.0016 0.0004 0.0007
Leishmania major heat shock protein 83-1 0.0046 0.0191 0.2784
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0198 0.1103
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0037 0.0137 0.0253
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0275 0.1152
Onchocerca volvulus Netrin receptor homolog 0.0063 0.0297 0.0501
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Schistosoma mansoni cpg binding protein 0.0028 0.008 0.0094
Chlamydia trachomatis glyceraldehyde-3-phosphate dehydrogenase 0.0067 0.0321 1
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0067 0.0321 0.138
Schistosoma mansoni microtubule-associated protein tau 0.1371 0.8496 1
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0037 0.0137 0.0224
Trichomonas vaginalis heat shock protein, putative 0.0046 0.0191 0.077
Treponema pallidum fructose-bisphosphate aldolase 0.0293 0.174 1
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Leishmania major heat shock protein 83-1 0.0046 0.0191 0.2784
Plasmodium falciparum potassium channel 0.0037 0.0137 0.0585
Brugia malayi Bromodomain containing protein 0.0226 0.1319 0.2435
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0003 0.0003
Echinococcus multilocularis potassium channel subfamily K 0.0037 0.0137 0.0137
Leishmania major heat shock protein 83-1 0.0046 0.0191 0.2784
Brugia malayi MH1 domain containing protein 0.0016 0.0004 0.0007
Toxoplasma gondii NAC domain-containing protein 0.0035 0.0122 0.0331
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0099 0.0207
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0614 0.3754 0.3754
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0072 0.0351 0.1117
Echinococcus granulosus sterol regulatory element binding protein 0.0084 0.0429 0.0505
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0198 0.0365
Loa Loa (eye worm) beta-lactamase 0.0072 0.0351 0.0573
Brugia malayi Death domain containing protein 0.0063 0.0297 0.0547
Onchocerca volvulus 0.0045 0.0186 0.0295
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0037 0.0137 0.0253
Leishmania major heat shock protein 83-1 0.0046 0.0191 0.2784
Onchocerca volvulus Huntingtin homolog 0.0123 0.0673 0.1198
Leishmania major hypothetical protein, conserved 0.003 0.0093 0.069
Echinococcus multilocularis alkaline phosphatase 0.016 0.0906 0.0906
Schistosoma mansoni methyl-cpg binding protein mbd 0.0176 0.1003 0.118
Echinococcus granulosus expressed conserved protein 0.0184 0.1054 0.1241
Echinococcus multilocularis cpg binding protein 0.0034 0.0114 0.0114
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0214 0.0251
Schistosoma mansoni glucose transport protein 0.0321 0.1914 0.2253
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0092 0.0092
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0045 0.0186 0.2886
Brugia malayi Sugar transporter family protein 0.0321 0.1914 0.3533
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.019 0.0351
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Loa Loa (eye worm) TWK-28 protein 0.0037 0.0137 0.0224
Echinococcus granulosus beta LACTamase domain containing family member 0.0072 0.0351 0.0413
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0037 0.0137 0.0253
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0046 0.0194 0.0228
Echinococcus multilocularis potassium channel subfamily K 8 0.0037 0.0137 0.0137
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0092 0.0108
Schistosoma mansoni rab6-interacting 0.002 0.0027 0.0031
Leishmania major heat shock protein 83-1 0.0046 0.0191 0.2784
Trypanosoma brucei heat shock protein, putative 0.0046 0.0191 0.2784
Loa Loa (eye worm) transcription factor SMAD2 0.0237 0.1389 0.2268
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0143 0.0143
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.008 0.0094
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0045 0.0186 0.0218
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0099 0.0386
Echinococcus granulosus intermediate filament protein 0.0027 0.0072 0.0085
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0143 0.0168
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0099 0.0823
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0092 0.0108
Loa Loa (eye worm) hypothetical protein 0.0045 0.0186 0.0303
Onchocerca volvulus 0.0045 0.0186 0.0295
Brugia malayi Major Facilitator Superfamily protein 0.0045 0.0186 0.0342
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0037 0.0137 0.0137
Trichomonas vaginalis heat shock protein, putative 0.0027 0.007 0.0124
Echinococcus granulosus solute carrier family 22 0.0045 0.0186 0.0218
Brugia malayi Inositol-1 0.0036 0.0131 0.0241
Schistosoma mansoni hypothetical protein 0.0036 0.0129 0.0152
Brugia malayi hypothetical protein 0.0045 0.0186 0.0342
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0099 0.0184
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0004 0.0007
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0318 0.5511
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0092 0.0121
Brugia malayi hypothetical protein 0.0045 0.0186 0.0342
Trichomonas vaginalis esterase, putative 0.0072 0.0351 0.1629
Echinococcus multilocularis solute carrier family 22 0.0045 0.0186 0.0186
Onchocerca volvulus 0.0072 0.0351 0.0602
Trichomonas vaginalis heat shock protein, putative 0.0043 0.0173 0.0675
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0092 0.0092
Brugia malayi glyceraldehyde 3-phosphate dehydrogenase 0.0021 0.0032 0.006
Toxoplasma gondii heat shock protein 90, putative 0.0046 0.0191 0.0699
Toxoplasma gondii heat shock protein 75, putative 0.0031 0.0094 0.0178
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0092 0.017
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0043 0.0173 0.2229
Leishmania major heat shock protein 83-1 0.0046 0.0191 0.2784
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0092 0.015
Trypanosoma brucei heat shock protein, putative 0.0046 0.0191 0.2784
Brugia malayi hypothetical protein 0.0037 0.0137 0.0253
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0318 0.5511
Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenase 0.0067 0.0321 0.156
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0047 0.0198 0.1103
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0122 0.1971
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0198 0.0365
Loa Loa (eye worm) TWK-7 protein 0.0037 0.0137 0.0224
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.0198 0.0554
Echinococcus granulosus Niemann Pick C1 protein 0.028 0.1655 0.1948
Trypanosoma cruzi hexose transporter, putative 0.0045 0.0186 0.3224
Trypanosoma brucei heat shock protein, putative 0.0046 0.0191 0.2784
Brugia malayi Uncoordinated protein 44 0.0063 0.0297 0.0547
Schistosoma mansoni hypothetical protein 0.017 0.0968 0.1139
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.016 0.0906 0.0906
Schistosoma mansoni hypothetical protein 0.0402 0.2425 0.2855
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0021 0.0032 0.018
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0318 0.1359
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Onchocerca volvulus 0.0234 0.1369 0.249
Echinococcus granulosus Protein patched homolog 1 0.0084 0.0429 0.0505
Loa Loa (eye worm) hypothetical protein 0.0364 0.2182 0.3563
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0037 0.0137 0.0253
Giardia lamblia Grp94/Hsp90 0.0043 0.0173 0.0224
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0198 0.2002
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Onchocerca volvulus 0.0027 0.0072 0.0085
Onchocerca volvulus 0.0047 0.0198 0.0318
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0293 0.0345
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0045 0.0186 0.0842
Trypanosoma brucei sugar transporter, putative 0.0045 0.0186 0.2673
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0113 0.0208
Echinococcus multilocularis lamin dm0 0.0027 0.0072 0.0072
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0092 0.0108
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0043 0.0173 0.1671
Schistosoma mansoni twik family of potassium channels-related 0.0037 0.0137 0.0161
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0004 0.0005
Schistosoma mansoni lipoxygenase 0.0118 0.0644 0.0758
Loa Loa (eye worm) hypothetical protein 0.0993 0.6124 1
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0044 0.0177 0.0289
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0091 0.0107
Loa Loa (eye worm) hypothetical protein 0.0045 0.0186 0.0303
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0003 0.0005
Echinococcus multilocularis small conductance calcium activated potassium 0.0993 0.6124 0.6124
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0072 0.0351 0.0573
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0037 0.0137 0.0253
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0037 0.0137 0.1632
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0321 0.1914 0.2253
Toxoplasma gondii ion channel protein 0.0037 0.0137 0.041
Echinococcus multilocularis heat shock protein 90 0.0046 0.0191 0.0191
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0092 0.0121
Trypanosoma cruzi ISWI complex protein 0.003 0.0093 0.139
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.021 0.0388
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0143 0.08 0.2768
Onchocerca volvulus 0.0047 0.02 0.0322
Echinococcus multilocularis Niemann Pick C1 protein 0.028 0.1655 0.1655
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0037 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0035 0.0123 0.0201
Onchocerca volvulus 0.0037 0.0137 0.0205
Leishmania major heat shock protein 83-1 0.0046 0.0191 0.2784
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0061 0.0752
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0044 0.0177 0.0208
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0321 0.1914 0.2253
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0067 0.0321 0.5587
Brugia malayi Endoplasmin precursor 0.0046 0.0191 0.0352
Entamoeba histolytica hypothetical protein 0.0036 0.0129 0.0211
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.174 0.9066
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0122 0.0404
Brugia malayi beta-NAC-like protein 0.0035 0.0122 0.0226
Trypanosoma brucei transcription factor BTF3, putative 0.0035 0.0122 0.1318
Mycobacterium ulcerans ion transport protein 0.0037 0.0137 0.0204
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0044 0.0177 0.3047
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Schistosoma mansoni twik family of potassium channels-related 0.0037 0.0137 0.0161
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0351 0.1629
Loa Loa (eye worm) hypothetical protein 0.0049 0.021 0.0343
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0099 0.0117
Onchocerca volvulus 0.0037 0.0137 0.0205
Trypanosoma brucei THT1 - hexose transporter, putative 0.01 0.0526 1
Leishmania major potassium channel subunit-like protein 0.0037 0.0137 0.1632
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0351 0.0413
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0092 0.017
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0196 0.1129 0.1329
Loa Loa (eye worm) hypothetical protein 0.0045 0.0186 0.0303
Echinococcus multilocularis heat shock protein 0.0046 0.0191 0.0191
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0027 0.0027
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0351 0.0413
Leishmania major heat shock protein 83-1 0.0046 0.0191 0.2784
Leishmania major glucose transporter, lmgt1 0.01 0.0526 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0037 0.0137 0.2261
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0111 0.0235
Brugia malayi nuclear receptor NHR-88 0.003 0.0092 0.017
Toxoplasma gondii sugar transporter ST1 0.0045 0.0186 0.0671
Loa Loa (eye worm) hypothetical protein 0.0045 0.0186 0.0303
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0123 0.0512
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0072 0.0351 0.3365
Mycobacterium ulcerans integral membrane transport protein 0.0045 0.0186 0.0919
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0037 0.0137 0.2261
Echinococcus multilocularis neuropeptide s receptor 0.0471 0.2854 0.2854
Onchocerca volvulus 0.0028 0.008 0.0099
Echinococcus granulosus tumor protein p63 0.0339 0.2026 0.2385
Onchocerca volvulus 0.003 0.0092 0.0121
Echinococcus multilocularis survival motor neuron protein 1 0.0233 0.1361 0.1361
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0137 0.0483
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0318 0.0318
Leishmania major ion transport protein-like protein 0.0037 0.0137 0.1632
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0318 0.5849
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0092 0.0092
Schistosoma mansoni nuclear hormone receptor 0.003 0.0092 0.0108
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0046 0.0194 0.0194
Schistosoma mansoni sugar transporter 0.0045 0.0186 0.0218
Onchocerca volvulus 0.0037 0.0137 0.0205
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Trypanosoma brucei THT1 - hexose transporter, putative 0.01 0.0526 1
Onchocerca volvulus 0.0045 0.0186 0.0295
Onchocerca volvulus 0.0027 0.0072 0.0085
Loa Loa (eye worm) hypothetical protein 0.0063 0.0298 0.0487
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0004 0.0005
Schistosoma mansoni hypothetical protein 0.0081 0.041 0.0482
Schistosoma mansoni hypothetical protein 0.0081 0.041 0.0482
Brugia malayi hypothetical protein 0.0036 0.0129 0.0238
Loa Loa (eye worm) hypothetical protein 0.0045 0.0186 0.0303
Trichomonas vaginalis sugar transporter, putative 0.01 0.0526 0.2568
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0072 0.0118
Brugia malayi beta-lactamase 0.0072 0.0351 0.0648
Mycobacterium tuberculosis Conserved protein 0.0072 0.0351 0.1117
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Echinococcus granulosus Smad4 0.0016 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0005
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0118 0.0644 0.0644
Schistosoma mansoni smad1 5 8 and 0.0016 0.0004 0.0005
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0111 0.0235
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0293 0.0293
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0037 0.0137 0.0253
Entamoeba histolytica transcription factor BTF3, putative 0.0035 0.0122 0.0173
Brugia malayi MH2 domain containing protein 0.0016 0.0004 0.0007
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0143 0.08 1
Brugia malayi TAR-binding protein 0.0062 0.0293 0.0542
Plasmodium vivax potassium channel, putative 0.0037 0.0137 0.0585
Onchocerca volvulus 0.0045 0.0186 0.0295
Schistosoma mansoni zinc finger protein 0.0041 0.0157 0.0184
Echinococcus multilocularis intestinal type alkaline phosphatase 0.016 0.0906 0.0906
Mycobacterium ulcerans transmembrane cation transporter 0.0037 0.0137 0.0204
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0067 0.0321 0.5918
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0137 0.0483
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0199 0.1148 0.1351
Loa Loa (eye worm) hypothetical protein 0.0086 0.0444 0.0725
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0131 0.0447
Loa Loa (eye worm) ICD-1 protein 0.0035 0.0122 0.02
Loa Loa (eye worm) hypothetical protein 0.0207 0.12 0.196
Loa Loa (eye worm) hypothetical protein 0.0047 0.0198 0.0323
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0092 0.0092
Mycobacterium ulcerans hypothetical protein 0.0047 0.0198 0.1103
Loa Loa (eye worm) hypothetical protein 0.088 0.5418 0.8847
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0067 0.0321 0.5918
Echinococcus multilocularis Niemann Pick C1 protein 0.0196 0.1129 0.1129
Echinococcus granulosus dnaJ subfamily B 0.0402 0.2425 0.2855
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0092 0.0108
Schistosoma mansoni netrin receptor unc5 0.0063 0.0297 0.0349
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0092 0.0108
Loa Loa (eye worm) hypothetical protein 0.0216 0.1256 0.2051
Plasmodium vivax heat shock protein 86, putative 0.0046 0.0191 0.0869
Mycobacterium tuberculosis Probable lipase LipD 0.0072 0.0351 0.1117
Loa Loa (eye worm) RNA binding protein 0.0062 0.0293 0.0479
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0139 0.0776 0.0913
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0131 0.0447
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0131 0.0107
Loa Loa (eye worm) hypothetical protein 0.0196 0.1129 0.1843
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0321 0.1914 0.1914
Echinococcus multilocularis protein patched 0.0084 0.0429 0.0429
Trypanosoma cruzi glucose transporter, putative 0.0045 0.0186 0.3224
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0037 0.0137 0.0253
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0196 0.1129 0.1129
Leishmania major glucose transporter, lmgt2 0.01 0.0526 1
Echinococcus granulosus death domain containing protein 0.0063 0.0297 0.0349
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0072 0.0133
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0139 0.0776 0.0776
Plasmodium vivax basic transcription factor 3b, putative 0.0035 0.0122 0.0508
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0067 0.0321 0.5587
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0044 0.0177 0.0289
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Onchocerca volvulus 0.0045 0.0186 0.0295
Brugia malayi HSF-type DNA-binding domain containing protein 0.0099 0.0526 0.0971
Brugia malayi nuclear hormone receptor 0.003 0.0092 0.017
Leishmania major glucose transporter, lmgt3 0.01 0.0526 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0293 0.174 0.9066
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0092 0.017
Brugia malayi photoreceptor-specific nuclear receptor 0.0267 0.1576 0.2908
Schistosoma mansoni sugar transporter 0.0045 0.0186 0.0218
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0293 0.0542
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0092 0.017
Brugia malayi MH2 domain containing protein 0.0016 0.0004 0.0007
Trypanosoma cruzi hexose transporter, putative 0.01 0.0526 1
Brugia malayi Sugar transporter family protein 0.0045 0.0186 0.0342
Trypanosoma brucei heat shock protein, putative 0.0046 0.0191 0.2784
Onchocerca volvulus Heat shock factor protein 2 homolog 0.0099 0.0526 0.0926
Onchocerca volvulus 0.0045 0.0186 0.0295
Plasmodium falciparum heat shock protein 90, putative 0.0027 0.007 0.023
Plasmodium falciparum heat shock protein 90 0.0046 0.0191 0.0869
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0037 0.0137 0.2261
Loa Loa (eye worm) endoplasmin 0.0046 0.0191 0.0311
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0031 0.0099 0.0192
Echinococcus granulosus solute carrier family 22 0.0045 0.0186 0.0218
Leishmania major heat shock protein 83-1 0.0046 0.0191 0.2784
Loa Loa (eye worm) PHD-finger family protein 0.0041 0.016 0.0261
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0092 0.0108
Brugia malayi beta-lactamase family protein 0.0072 0.0351 0.0648
Trypanosoma cruzi heat shock protein 85, putative 0.0046 0.0191 0.3327
Echinococcus multilocularis calcium activated potassium channel variant 0.0037 0.0137 0.0137
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0131 0.0131
Brugia malayi nuclear receptor RXR 0.0016 0.0003 0.0005
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0037 0.0137 0.0262
Trichomonas vaginalis sugar transporter, putative 0.0045 0.0186 0.0742
Brugia malayi Major Facilitator Superfamily protein 0.0045 0.0186 0.0342
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0067 0.0321 0.138
Schistosoma mansoni coup transcription factor 0.003 0.0092 0.0108
Loa Loa (eye worm) hypothetical protein 0.0045 0.0186 0.0303
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.119 0.1943
Echinococcus granulosus small conductance calcium activated potassium 0.0993 0.6124 0.7209
Schistosoma mansoni zinc finger protein 0.003 0.0093 0.011
Onchocerca volvulus 0.0045 0.0186 0.0295
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0131 0.0374
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0092 0.017
Plasmodium vivax heat shock protein 90, putative 0.0031 0.0094 0.0357
Echinococcus multilocularis solute carrier family 22 0.0045 0.0186 0.0186
Plasmodium falciparum basic transcription factor 3b, putative 0.0035 0.0122 0.0508
Echinococcus granulosus calcium activated potassium channel variant 0.0037 0.0137 0.0161
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0005
Echinococcus granulosus nuclear factor of activated T cells 5 0.0614 0.3754 0.4419
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.015
Trypanosoma brucei glucose transporter, putative 0.01 0.0526 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0137 0.0224
Trypanosoma brucei heat shock protein 84, putative 0.0031 0.0094 0.0707
Brugia malayi Sugar transporter family protein 0.0045 0.0186 0.0342

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) > 50 ug ml-1 Antiproliferative activity against human HT1080 cells assessed as inhibition of cell proliferation after 72 hrs by CCK8 assay ChEMBL. 23451797

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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