Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.033 | 0.0375 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0074 | 0.072 | 0.2605 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.0737 | 0.8808 | 1 |
Trichomonas vaginalis | esterase, putative | 0.0074 | 0.072 | 0.2605 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0361 | 0.4225 | 0.479 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0737 | 0.8808 | 1 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0018 | 0.0043 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0361 | 0.4225 | 0.479 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0016 | 0.0012 | 0.0013 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0737 | 0.8808 | 1 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0361 | 0.4225 | 0.479 |
Mycobacterium leprae | Probable lipase LipE | 0.0074 | 0.072 | 0.5 |
Brugia malayi | MH2 domain containing protein | 0.0116 | 0.1234 | 0.1389 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0046 | 0.0377 | 0.0428 |
Echinococcus granulosus | acetylcholinesterase | 0.0312 | 0.3619 | 0.4101 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.072 | 0.0805 |
Trichomonas vaginalis | set domain proteins, putative | 0.0232 | 0.2643 | 1 |
Leishmania major | carbonic anhydrase-like protein | 0.0737 | 0.8808 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0404 | 0.0458 |
Schistosoma mansoni | protein phosphatase 2C | 0.0016 | 0.0012 | 0.0013 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0472 | 0.5579 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0245 | 0.0265 |
Echinococcus multilocularis | GPCR, family 2 | 0.0048 | 0.0404 | 0.0392 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0046 | 0.0377 | 0.0415 |
Loa Loa (eye worm) | hypothetical protein | 0.0312 | 0.3619 | 0.4101 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0053 | 0.0461 | 0.1608 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0461 | 0.0511 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0101 | 0.1055 | 0.1044 |
Loa Loa (eye worm) | carboxylesterase | 0.0312 | 0.3619 | 0.4101 |
Schistosoma mansoni | patched 1 | 0.0043 | 0.0349 | 0.0396 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0145 | 0.1585 | 0.1789 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0053 | 0.0461 | 0.0523 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0017 | 0.0028 | 0.0018 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0074 | 0.072 | 0.2605 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0104 | 0.1082 | 0.1217 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0312 | 0.3619 | 0.4101 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.033 | 0.0375 |
Mycobacterium ulcerans | hypothetical protein | 0.0074 | 0.072 | 1 |
Echinococcus multilocularis | carbonic anhydrase | 0.0361 | 0.4225 | 0.4218 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0461 | 0.0511 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0059 | 0.0543 | 0.0532 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0086 | 0.0074 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.0737 | 0.8808 | 1 |
Echinococcus granulosus | expressed conserved protein | 0.0095 | 0.098 | 0.1101 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0162 | 0.017 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0074 | 0.072 | 0.0709 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.0913 | 0.1024 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0074 | 0.072 | 0.0805 |
Brugia malayi | PHD-finger family protein | 0.0024 | 0.0114 | 0.0116 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.005 | 0.0433 | 0.0491 |
Brugia malayi | Carboxylesterase family protein | 0.0053 | 0.0461 | 0.0511 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0737 | 0.8808 | 1 |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.0175 | 0.2298 |
Echinococcus multilocularis | carbonic anhydrase II | 0.0737 | 0.8808 | 0.8806 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0053 | 0.0461 | 0.0511 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0067 | 0.0633 | 0.0719 |
Echinococcus multilocularis | carbonic anhydrase | 0.0361 | 0.4225 | 0.4218 |
Onchocerca volvulus | 0.0074 | 0.072 | 0.2211 | |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0101 | 0.1055 | 0.1186 |
Brugia malayi | CHE-14 protein | 0.0043 | 0.0349 | 0.0384 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0059 | 0.0543 | 0.0532 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0074 | 0.072 | 0.1224 |
Brugia malayi | Cytochrome P450 family protein | 0.0025 | 0.0122 | 0.0125 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0048 | 0.0404 | 0.0445 |
Schistosoma mansoni | eyes absent homolog | 0.009 | 0.0913 | 0.1036 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0067 | 0.0633 | 0.0719 |
Loa Loa (eye worm) | carboxylesterase | 0.0053 | 0.0461 | 0.0511 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0361 | 0.4225 | 0.4797 |
Echinococcus granulosus | carbonic anhydrase | 0.0361 | 0.4225 | 0.479 |
Schistosoma mansoni | hypothetical protein | 0.0104 | 0.1082 | 0.1229 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0377 | 0.0428 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0043 | 0.0049 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0361 | 0.4225 | 0.479 |
Echinococcus multilocularis | acetylcholinesterase | 0.0312 | 0.3619 | 0.3612 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0245 | 0.0233 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0043 | 0.0349 | 0.0384 |
Brugia malayi | Carboxylesterase family protein | 0.0312 | 0.3619 | 0.4101 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0018 | 0.0034 | 0.0026 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0074 | 0.072 | 0.0818 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.1055 | 0.1186 |
Brugia malayi | hypothetical protein | 0.009 | 0.0913 | 0.1024 |
Loa Loa (eye worm) | carboxylesterase | 0.0053 | 0.0461 | 0.0511 |
Echinococcus granulosus | carboxylesterase 5A | 0.0312 | 0.3619 | 0.4101 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0048 | 0.0404 | 0.0445 |
Toxoplasma gondii | ABC1 family protein | 0.0074 | 0.072 | 0.1682 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0053 | 0.0461 | 0.617 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0737 | 0.8808 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0053 | 0.0461 | 0.0755 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0461 | 0.0511 |
Onchocerca volvulus | 0.0074 | 0.072 | 0.2211 | |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0018 | 0.0043 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0116 | 0.1234 | 0.1389 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0074 | 0.072 | 0.0818 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0053 | 0.0461 | 0.0523 |
Mycobacterium leprae | conserved hypothetical protein | 0.0074 | 0.072 | 0.5 |
Echinococcus multilocularis | neuroligin | 0.0053 | 0.0461 | 0.045 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0067 | 0.0633 | 0.8713 |
Plasmodium falciparum | carbonic anhydrase | 0.0361 | 0.4225 | 1 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0016 | 0.0012 | 0.0013 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0067 | 0.0633 | 0.0719 |
Schistosoma mansoni | acetylcholinesterase | 0.0053 | 0.0461 | 0.0523 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0175 | 0.0163 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0074 | 0.072 | 0.0805 |
Schistosoma mansoni | carbonic anhydrase | 0.0361 | 0.4225 | 0.4797 |
Brugia malayi | Bromodomain containing protein | 0.0037 | 0.0273 | 0.0296 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0067 | 0.0633 | 0.8713 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0018 | 0.0043 | 0.0035 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0312 | 0.3619 | 0.3612 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0046 | 0.0377 | 0.0428 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0074 | 0.072 | 0.0818 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0273 | 0.0297 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0067 | 0.0633 | 0.0622 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0067 | 0.0633 | 0.1475 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0018 | 0.0034 | 0.0023 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0074 | 0.072 | 0.1224 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0053 | 0.0461 | 0.045 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0018 | 0.0043 | 0.0049 |
Schistosoma mansoni | hypothetical protein | 0.0178 | 0.1992 | 0.2262 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0053 | 0.0461 | 0.045 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.072 | 0.0805 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0737 | 0.8808 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0053 | 0.0461 | 0.0511 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0059 | 0.0543 | 0.0604 |
Echinococcus granulosus | tumor protein p63 | 0.0344 | 0.4014 | 0.455 |
Toxoplasma gondii | exonuclease III APE | 0.0018 | 0.0043 | 0.0074 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0404 | 0.0458 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.0021 | 0.001 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0043 | 0.0049 |
Mycobacterium tuberculosis | Conserved protein | 0.0074 | 0.072 | 0.1224 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0074 | 0.072 | 0.2605 |
Loa Loa (eye worm) | beta-lactamase | 0.0074 | 0.072 | 0.0805 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0016 | 0.0012 | 0.0013 |
Brugia malayi | beta-lactamase family protein | 0.0074 | 0.072 | 0.0805 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0016 | 0.0012 | 0.0013 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0074 | 0.072 | 0.0818 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0058 | 0.0526 | 0.0515 |
Echinococcus multilocularis | zinc finger protein | 0.0019 | 0.0051 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.0913 | 0.1024 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0361 | 0.4225 | 0.479 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0461 | 0.0511 |
Schistosoma mansoni | zinc finger protein | 0.0019 | 0.0051 | 0.0058 |
Loa Loa (eye worm) | hypothetical protein | 0.0361 | 0.4225 | 0.479 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0018 | 0.0043 | 0.0035 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0029 | 0.0175 | 0.0198 |
Echinococcus granulosus | carbonic anhydrase | 0.0361 | 0.4225 | 0.479 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.1667 | 0.1882 |
Schistosoma mansoni | jumonji domain containing protein | 0.0059 | 0.0543 | 0.0616 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0074 | 0.072 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0074 | 0.072 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0061 | 0.0566 | 0.0642 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0301 | 0.0329 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0377 | 0.0416 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0053 | 0.0461 | 0.0523 |
Brugia malayi | Pre-SET motif family protein | 0.0203 | 0.23 | 0.2602 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0086 | 0.0084 |
Schistosoma mansoni | hypothetical protein | 0.0178 | 0.1992 | 0.2262 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0018 | 0.0043 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0312 | 0.3619 | 0.4101 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0043 | 0.0439 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0043 | 0.0049 |
Echinococcus multilocularis | acetylcholinesterase | 0.0312 | 0.3619 | 0.3612 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0053 | 0.0461 | 0.1608 |
Schistosoma mansoni | gliotactin | 0.0053 | 0.0461 | 0.0523 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0043 | 0.0349 | 0.0338 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0086 | 0.0097 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0377 | 0.0366 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0461 | 0.0511 |
Schistosoma mansoni | bromodomain containing protein | 0.0061 | 0.0569 | 0.0646 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.072 | 0.0805 |
Brugia malayi | beta-lactamase family protein | 0.0074 | 0.072 | 0.0805 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0361 | 0.4225 | 0.4797 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0469 | 0.0519 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0043 | 0.0349 | 0.0384 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0058 | 0.0526 | 0.0585 |
Echinococcus granulosus | neuroligin | 0.0053 | 0.0461 | 0.0511 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0103 | 0.1074 | 0.1219 |
Onchocerca volvulus | 0.0053 | 0.0461 | 0.116 | |
Echinococcus multilocularis | expressed conserved protein | 0.0095 | 0.098 | 0.0969 |
Echinococcus multilocularis | geminin | 0.0178 | 0.1992 | 0.1983 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0361 | 0.4225 | 0.479 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0152 | 0.1667 | 0.1882 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0175 | 0.0185 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0048 | 0.0404 | 0.0445 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0043 | 0.0049 |
Schistosoma mansoni | phd/f-box containing protein | 0.0016 | 0.0012 | 0.0013 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.0349 | 0.1178 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0101 | 0.1055 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0461 | 0.0511 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0461 | 0.0511 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0377 | 0.0366 |
Echinococcus granulosus | carbonic anhydrase II | 0.0737 | 0.8808 | 1 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0737 | 0.8808 | 1 |
Onchocerca volvulus | 0.005 | 0.0433 | 0.1046 | |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0074 | 0.072 | 0.0805 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0074 | 0.072 | 0.1224 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0018 | 0.0043 | 0.0049 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0074 | 0.072 | 0.2605 |
Echinococcus granulosus | zinc finger protein | 0.0019 | 0.0051 | 0.0044 |
Echinococcus granulosus | GPCR family 2 | 0.0048 | 0.0404 | 0.0445 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0053 | 0.0461 | 0.0755 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0404 | 0.0445 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0377 | 0.0416 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0048 | 0.0404 | 0.0392 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0053 | 0.0461 | 0.0523 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0048 | 0.0404 | 0.0392 |
Mycobacterium ulcerans | lipase LipD | 0.0074 | 0.072 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0074 | 0.072 | 1 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0043 | 0.0074 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.0175 | 0.0386 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0145 | 0.1585 | 0.1575 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0074 | 0.072 | 0.1224 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0063 | 0.0072 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0067 | 0.0633 | 0.8713 |
Brugia malayi | jmjC domain containing protein | 0.0059 | 0.0543 | 0.0604 |
Loa Loa (eye worm) | hypothetical protein | 0.0361 | 0.4225 | 0.479 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0018 | 0.0043 | 0.0031 |
Brugia malayi | beta-lactamase | 0.0074 | 0.072 | 0.0805 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0312 | 0.3619 | 0.4109 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0016 | 0.0012 | 0.0013 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0361 | 0.4225 | 0.479 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0067 | 0.0633 | 0.1066 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0021 | 0.0024 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0063 | 0.0058 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0377 | 0.0428 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0152 | 0.1667 | 0.1882 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0074 | 0.072 | 0.1224 |
Leishmania major | hypothetical protein, conserved | 0.0074 | 0.072 | 0.0818 |
Echinococcus multilocularis | protein patched | 0.0043 | 0.0349 | 0.0338 |
Onchocerca volvulus | 0.0053 | 0.0461 | 0.116 | |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0018 | 0.0043 | 0.0035 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0048 | 0.0404 | 0.0445 |
Onchocerca volvulus | 0.0053 | 0.0461 | 0.116 | |
Echinococcus multilocularis | carbonic anhydrase | 0.0361 | 0.4225 | 0.4218 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0061 | 0.0566 | 0.0642 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0377 | 0.0416 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0361 | 0.4225 | 0.4797 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0043 | 0.0349 | 0.0384 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0061 | 0.0566 | 0.063 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0046 | 0.0377 | 0.0365 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0025 | 0.0122 | 0.0125 |
Brugia malayi | Carboxylesterase family protein | 0.0312 | 0.3619 | 0.4101 |
Brugia malayi | hypothetical protein | 0.0053 | 0.0461 | 0.0511 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0152 | 0.1667 | 0.1882 |
Mycobacterium tuberculosis | Conserved protein | 0.0074 | 0.072 | 0.1224 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0067 | 0.0633 | 0.0706 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.072 | 0.0805 |
Brugia malayi | Bromodomain containing protein | 0.0073 | 0.0708 | 0.0791 |
Onchocerca volvulus | 0.0053 | 0.0461 | 0.116 | |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.033 | 0.0375 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0048 | 0.0404 | 0.0445 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0021 | 0.0024 |
Brugia malayi | Carboxylesterase family protein | 0.0053 | 0.0461 | 0.0511 |
Schistosoma mansoni | hypothetical protein | 0.0361 | 0.4225 | 0.4797 |
Toxoplasma gondii | hypothetical protein | 0.0361 | 0.4225 | 1 |
Onchocerca volvulus | 0.0074 | 0.072 | 0.2211 | |
Echinococcus multilocularis | protein dispatched 1 | 0.005 | 0.0424 | 0.0413 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0349 | 0.0384 |
Onchocerca volvulus | 0.0232 | 0.2643 | 1 | |
Echinococcus granulosus | geminin | 0.0178 | 0.1992 | 0.2252 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0203 | 0.23 | 0.2602 |
Leishmania major | hypothetical protein, conserved | 0.0016 | 0.0012 | 0.0013 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0074 | 0.072 | 0.1224 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0175 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0433 | 0.0479 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0404 | 0.0458 |
Schistosoma mansoni | jumonji domain containing protein | 0.0016 | 0.0012 | 0.0013 |
Echinococcus granulosus | carbonic anhydrase | 0.0361 | 0.4225 | 0.479 |
Mycobacterium tuberculosis | Conserved protein | 0.0074 | 0.072 | 0.1224 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0074 | 0.072 | 0.2605 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0377 | 0.0416 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0053 | 0.0461 | 0.045 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.072 | 0.0805 |
Brugia malayi | Carboxylesterase family protein | 0.0053 | 0.0461 | 0.0511 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0053 | 0.0461 | 0.0755 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0404 | 0.0458 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0053 | 0.0461 | 0.0511 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.0021 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.072 | 0.0805 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0377 | 0.0415 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0074 | 0.072 | 0.0818 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0324 | 0.0355 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0053 | 0.0461 | 0.0523 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0074 | 0.072 | 0.1224 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0061 | 0.0566 | 0.063 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0377 | 0.0428 |
Echinococcus multilocularis | tumor protein p63 | 0.0344 | 0.4014 | 0.4007 |
Brugia malayi | jmjC domain containing protein | 0.0061 | 0.0566 | 0.063 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0657 | 0.0733 |
Loa Loa (eye worm) | hypothetical protein | 0.0312 | 0.3619 | 0.4101 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.033 | 0.0375 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0737 | 0.8808 | 1 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0053 | 0.0461 | 0.0511 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0101 | 0.1055 | 0.1186 |
Mycobacterium ulcerans | beta-lactamase | 0.0074 | 0.072 | 1 |
Onchocerca volvulus | 0.0053 | 0.0461 | 0.116 | |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.1082 | 0.1217 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0116 | 0.1234 | 0.1389 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.