Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0026 | 0.2659 | 0.5 | |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.2659 | 0.2591 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0066 | 1 | 1 |
Echinococcus granulosus | lamin | 0.0026 | 0.2659 | 0.2591 |
Echinococcus granulosus | carboxylesterase 5A | 0.0066 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.2659 | 0.2659 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.2659 | 0.2591 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.6114 | 0.6114 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.2659 | 0.2389 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.6114 | 0.6078 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.2659 | 0.2659 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.6114 | 0.4706 |
Echinococcus multilocularis | acetylcholinesterase | 0.0066 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.6114 | 0.6078 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.2659 | 0.2659 |
Onchocerca volvulus | 0.0026 | 0.2659 | 0.5 | |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.2659 | 0.2389 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0066 | 1 | 1 |
Echinococcus multilocularis | musashi | 0.0026 | 0.2659 | 0.2591 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.6114 | 0.6078 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.2568 | 0.2568 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.6114 | 0.6078 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0354 | 0.0354 |
Brugia malayi | Carboxylesterase family protein | 0.0066 | 1 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.6114 | 0.5971 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.6114 | 0.4706 |
Loa Loa (eye worm) | carboxylesterase | 0.0066 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0066 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0066 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0066 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.6114 | 0.4706 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 1 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.2659 | 0.2591 |
Echinococcus multilocularis | lamin | 0.0026 | 0.2659 | 0.2591 |
Echinococcus granulosus | acetylcholinesterase | 0.0066 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0091 | 0.0091 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.