Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0003 | 0.0003 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0165 | 0.1992 | 0.6425 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0165 | 0.1992 | 0.6425 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0003 | 0.0003 |
Brugia malayi | Carboxylesterase family protein | 0.0133 | 0.1575 | 0.1587 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0.0003 | 0.0016 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0003 | 0.0003 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0133 | 0.1575 | 0.5079 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0173 | 0.1099 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0003 | 0.0003 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.0173 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0173 | 0.1099 |
Echinococcus multilocularis | protein dispatched 1 | 0.0047 | 0.0479 | 0.0479 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0174 | 0.2106 | 0.6792 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0003 | 0.0003 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0018 | 0.0112 | 0.0113 |
Echinococcus granulosus | acetylcholinesterase | 0.0785 | 0.9926 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0003 | 0.0003 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.1575 | 0.1587 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0133 | 0.1575 | 1 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0133 | 0.1575 | 0.1587 |
Loa Loa (eye worm) | carboxylesterase | 0.0785 | 0.9926 | 1 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0098 | 0.1125 | 0.1134 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0003 | 0.0003 |
Brugia malayi | Carboxylesterase family protein | 0.0133 | 0.1575 | 0.1587 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0785 | 0.9926 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0252 | 0.3101 | 0.3124 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0003 | 0.0003 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0133 | 0.1575 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0785 | 0.9926 | 0.9926 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0003 | 0.0003 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0003 | 0.0003 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0017 | 0.0098 | 0.8782 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.1575 | 0.1587 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0003 | 0.0003 |
Schistosoma mansoni | patched 1 | 0.0041 | 0.0405 | 0.0408 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.001 | 0.00000034704 | 0.0000011191 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0098 | 0.0099 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0098 | 0.0099 |
Brugia malayi | Carboxylesterase family protein | 0.0133 | 0.1575 | 0.1587 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0133 | 0.1575 | 0.1587 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0112 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0003 | 0.0003 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0252 | 0.3101 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0173 | 0.1565 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0003 | 0.0003 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0252 | 0.3101 | 0.3124 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0003 | 0.0003 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0096 | 0.1106 | 0.1114 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0041 | 0.0405 | 0.0408 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0173 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0003 | 0.0003 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0112 | 0.0113 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0003 | 0.0003 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.0173 | 0.1565 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0003 | 0.0003 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0096 | 0.1106 | 1 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.0098 | 0.0081 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0018 | 0.0112 | 0.0112 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.0173 | 0.1099 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0003 | 0.0003 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0405 | 0.0408 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0133 | 0.1575 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.1106 | 0.1114 |
Schistosoma mansoni | acetylcholinesterase | 0.0133 | 0.1575 | 0.1587 |
Toxoplasma gondii | exonuclease III APE | 0.0018 | 0.0112 | 1 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0018 | 0.0112 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0003 | 0.0003 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0133 | 0.1575 | 0.1587 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0386 | 0.0388 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0405 | 0.1304 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0173 | 0.0174 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0098 | 0.0099 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0003 | 0.0003 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0133 | 0.1575 | 0.1575 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0133 | 0.1575 | 0.1575 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0003 | 0.0003 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0133 | 0.1575 | 0.5079 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | carboxylesterase | 0.0133 | 0.1575 | 0.1587 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0096 | 0.1106 | 0.1114 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0041 | 0.0405 | 0.0408 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0173 | 0.1565 |
Echinococcus multilocularis | neuroligin | 0.0133 | 0.1575 | 0.1575 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0003 | 0.0003 |
Schistosoma mansoni | gliotactin | 0.0133 | 0.1575 | 0.1587 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0386 | 0.0388 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0041 | 0.0405 | 0.0408 |
Loa Loa (eye worm) | hypothetical protein | 0.0785 | 0.9926 | 1 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0133 | 0.1575 | 0.1587 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0785 | 0.9926 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0003 | 0.0003 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0165 | 0.1992 | 0.6425 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0003 | 0.0003 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0003 | 0.0003 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0112 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0785 | 0.9926 | 1 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0386 | 0.0388 |
Onchocerca volvulus | 0.0133 | 0.1575 | 0.7905 | |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0003 | 0.0003 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0003 | 0.0003 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0098 | 0.0099 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0173 | 0.0174 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0003 | 0.0003 |
Schistosoma mansoni | chromosome transmission fidelity factor | 0.001 | 0.00000034704 | 0.00000034963 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0137 | 0.1634 | 0.1634 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0018 | 0.0112 | 0.0113 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0133 | 0.1575 | 0.1587 |
Loa Loa (eye worm) | hypothetical protein | 0.0785 | 0.9926 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0252 | 0.3101 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.1575 | 0.1587 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0785 | 0.9926 | 0.9926 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0003 | 0.0003 |
Echinococcus multilocularis | expressed conserved protein | 0.009 | 0.1032 | 0.1032 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0523 | 0.0527 |
Onchocerca volvulus | 0.0133 | 0.1575 | 0.7905 | |
Echinococcus granulosus | expressed conserved protein | 0.009 | 0.1032 | 0.1039 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0133 | 0.1575 | 1 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0018 | 0.0112 | 0.071 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.0173 | 0.0584 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0017 | 0.0098 | 0.8782 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0018 | 0.0112 | 1 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0018 | 0.0112 | 0.0113 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0165 | 0.1992 | 0.6425 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0133 | 0.1575 | 0.1587 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0003 | 0.0003 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0003 | 0.0003 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0003 | 0.0003 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0252 | 0.3101 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0003 | 0.0003 |
Entamoeba histolytica | Activator 1 140 kDa subunit, putative | 0.001 | 0.00000034704 | 0.0000031374 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0133 | 0.1575 | 0.1575 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0173 | 1 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0386 | 0.0388 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0003 | 0.0003 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0112 | 0.0113 |
Echinococcus multilocularis | acetylcholinesterase | 0.0785 | 0.9926 | 0.9926 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.1575 | 0.1587 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.1575 | 0.1587 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0.0003 | 0.0016 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0003 | 0.0003 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0165 | 0.1992 | 0.6425 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0003 | 0.0003 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0174 | 0.2106 | 0.6792 |
Echinococcus multilocularis | replication factor c subunit 1 | 0.001 | 0.00000034704 | 0.00000034704 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0003 | 0.0003 |
Echinococcus granulosus | carboxylesterase 5A | 0.0785 | 0.9926 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0165 | 0.1992 | 0.6425 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0096 | 0.1106 | 0.1106 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0003 | 0.0003 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0.0003 | 0.0016 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.0173 | 1 |
Trichomonas vaginalis | replication factor C large subunit, putative | 0.001 | 0.00000034704 | 0.0000011191 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0017 | 0.0098 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0252 | 0.3101 | 1 |
Onchocerca volvulus | 0.0133 | 0.1575 | 0.7905 | |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0003 | 0.0003 |
Brugia malayi | Carboxylesterase family protein | 0.0133 | 0.1575 | 0.1587 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0112 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0003 | 0.0003 |
Onchocerca volvulus | 0.0133 | 0.1575 | 0.7905 | |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0003 | 0.0003 |
Brugia malayi | Carboxylesterase family protein | 0.0785 | 0.9926 | 1 |
Echinococcus multilocularis | protein patched | 0.0041 | 0.0405 | 0.0405 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0173 | 0.0174 |
Brugia malayi | CHE-14 protein | 0.0041 | 0.0405 | 0.0408 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0173 | 0.0174 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0003 | 0.0003 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0003 | 0.0003 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0098 | 0.0099 |
Onchocerca volvulus | 0.001 | 0.0003 | 0.0016 | |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0137 | 0.1634 | 0.1646 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0003 | 0.0003 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0133 | 0.1575 | 0.1587 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0003 | 0.0003 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0165 | 0.1992 | 1 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0112 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0173 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0003 | 0.0003 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.0173 | 0.1099 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0252 | 0.3101 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0003 | 0.0003 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0003 | 0.0003 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0018 | 0.0112 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0173 | 0.1099 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0003 | 0.0003 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0003 | 0.0003 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.0173 | 0.1099 |
Loa Loa (eye worm) | carboxylesterase | 0.0133 | 0.1575 | 0.1587 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.0173 | 0.0584 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0018 | 0.0112 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0003 | 0.0003 |
Echinococcus granulosus | acetylcholinesterase | 0.0785 | 0.9926 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0173 | 0.1099 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0112 | 0.0361 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0133 | 0.1575 | 0.1587 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0252 | 0.3101 | 1 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0041 | 0.0405 | 0.0405 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0003 | 0.0003 |
Brugia malayi | hypothetical protein | 0.0133 | 0.1575 | 0.1587 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0165 | 0.1992 | 0.6425 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.001 | 0.00000034704 | 0.0000011191 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0003 | 0.0003 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0173 | 0.0174 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.0173 | 0.1099 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0003 | 0.0003 |
Echinococcus granulosus | neuroligin | 0.0133 | 0.1575 | 0.1587 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0173 | 0.0174 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0017 | 0.0098 | 0.0624 |
Onchocerca volvulus | 0.0023 | 0.0173 | 0.0869 | |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0003 | 0.0003 |
Echinococcus granulosus | replication factor c subunit 1 | 0.001 | 0.00000034704 | 0.00000034963 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0018 | 0.0112 | 0.1011 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0018 | 0.0112 | 0.0173 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0112 | 0.0361 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.1575 | 0.1587 |
Onchocerca volvulus | 0.0133 | 0.1575 | 0.7905 | |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.1575 | 0.1587 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0003 | 0.0003 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | Antimalarial activity against Plasmodium chabaudi chabaudi infected in mouse assessed as reduction in parasitemia at 7.1 mg/day administered as infusion on days 4 to 6 | ChEMBL. | 23410043 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.