Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0 | 0.5 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0065 | 0.0033 | 1 |
Mycobacterium ulcerans | 3-oxoacyl-ACP synthase | 1.1857 | 1 | 0.5 |
Mycobacterium tuberculosis | 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) | 1.1857 | 1 | 0.5 |
Entamoeba histolytica | fatty acid elongase, putative | 0.154 | 0.128 | 0.5 |
Mycobacterium ulcerans | beta-ketoacyl synthase-like protein | 1.1857 | 1 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 1.1857 | 1 | 0.5 |
Plasmodium vivax | beta-ketoacyl-acyl carrier protein synthase III precursor, putative | 1.1857 | 1 | 1 |
Entamoeba histolytica | fatty acid elongase, putative | 0.154 | 0.128 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0021 | 0.6462 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0033 | 1 |
Entamoeba histolytica | fatty acid elongase, putative | 0.154 | 0.128 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0033 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0018 | 0.3985 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0018 | 0.5384 |
Entamoeba histolytica | fatty acid elongase, putative | 0.154 | 0.128 | 0.5 |
Mycobacterium ulcerans | 3-oxoacyl-ACP synthase | 1.1857 | 1 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0021 | 0.6462 |
Entamoeba histolytica | fatty acid elongase, putative | 0.154 | 0.128 | 0.5 |
Brugia malayi | TAR-binding protein | 0.0065 | 0.0033 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0033 | 1 |
Brugia malayi | RNA binding protein | 0.0065 | 0.0033 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0008 | 0.2326 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0033 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0065 | 0.0033 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0021 | 0.6462 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0008 | 0.2326 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0021 | 0.6462 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0033 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0 | 0.5 |
Plasmodium falciparum | beta-ketoacyl-ACP synthase III | 1.1857 | 1 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0065 | 0.0033 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0018 | 0.5384 |
Loa Loa (eye worm) | TAR-binding protein | 0.0065 | 0.0033 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0065 | 0.0033 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0018 | 0.3985 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0018 | 0.3985 |
Loa Loa (eye worm) | RNA binding protein | 0.0065 | 0.0033 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.