Detailed information for compound 173867

Basic information

Technical information
  • TDR Targets ID: 173867
  • Name: 3-[(2S)-3-[4-(2-hydroxyethyl)piperazin-1-yl]- 2-(naphthalen-2-ylsulfonylamino)-3-oxopropyl] benzenecarboximidamide
  • MW: 509.62 | Formula: C26H31N5O4S
  • H donors: 3 H acceptors: 4 LogP: 1.75 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 2
  • SMILES: OCCN1CCN(CC1)C(=O)[C@@H](NS(=O)(=O)c1ccc2c(c1)cccc2)Cc1cccc(c1)C(=N)N
  • InChi: 1S/C26H31N5O4S/c27-25(28)22-7-3-4-19(16-22)17-24(26(33)31-12-10-30(11-13-31)14-15-32)29-36(34,35)23-9-8-20-5-1-2-6-21(20)18-23/h1-9,16,18,24,29,32H,10-15,17H2,(H3,27,28)/t24-/m0/s1
  • InChiKey: SVQXGJDWUSQUPO-DEOSSOPVSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-[(2S)-3-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(2-naphthylsulfonylamino)-3-oxo-propyl]benzamidine
  • 3-[(2S)-3-[4-(2-hydroxyethyl)-1-piperazinyl]-2-(2-naphthalenylsulfonylamino)-3-oxopropyl]benzamidine
  • 3-[(2S)-3-[4-(2-hydroxyethyl)piperazin-1-yl]-2-(naphthalen-2-ylsulfonylamino)-3-oxo-propyl]benzenecarboximidamide
  • 3-[(2S)-3-[4-(2-hydroxyethyl)piperazino]-3-keto-2-(2-naphthylsulfonylamino)propyl]benzamidine
  • 3-[(2S)-3-[4-(2-hydroxyethyl)-1-piperazinyl]-2-(2-naphthylsulfonylamino)-3-oxopropyl]benzamidine
  • 3-[(2S)-3-[4-(2-hydroxyethyl)piperazin-1-yl]-3-keto-2-(2-naphthylsulfonylamino)propyl]benzamidine

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Bos taurus Thrombin Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.1824 0.2787
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Schistosoma mansoni tyrosine kinase 0.0198 0.1824 0.3109
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0198 0.1824 0.3094
Schistosoma mansoni tyrosine kinase 0.0577 0.5867 1
Brugia malayi bone morphogenetic protein type 1 receptor 0.0198 0.1824 0.1824
Schistosoma mansoni cell adhesion molecule 0.0063 0.0377 0.0642
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Schistosoma mansoni tensin 0.0379 0.3749 0.639
Schistosoma mansoni tyrosine kinase 0.0198 0.1824 0.3109
Loa Loa (eye worm) hypothetical protein 0.0198 0.1824 0.1824
Schistosoma mansoni tyrosine kinase 0.0198 0.1824 0.3109
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Entamoeba histolytica tyrosine kinase, putative 0.0198 0.1824 0.2787
Giardia lamblia Kinase, NEK 0.0198 0.1824 0.8709
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0577 0.5867 1
Loa Loa (eye worm) hypothetical protein 0.0379 0.3749 0.3749
Onchocerca volvulus 0.0198 0.1824 0.1928
Schistosoma mansoni protein kinase 0.0201 0.1852 0.3157
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.021 0.1953 0.3313
Echinococcus granulosus suppressor of cytokine signaling 7 0.0379 0.3749 0.6359
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Echinococcus granulosus p2X purinoceptor 4 0.0378 0.3745 0.6353
Brugia malayi Fibronectin type III domain containing protein 0.0047 0.0212 0.0212
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Loa Loa (eye worm) RGC/RGC protein kinase 0.0198 0.1824 0.1824
Echinococcus granulosus tyrosine kinase 0.0577 0.5867 0.9952
Echinococcus granulosus integrin linked protein kinase 0.0198 0.1824 0.3094
Trypanosoma cruzi cdc2-related kinase 3 0.022 0.2055 1
Echinococcus granulosus twitchin 0.0062 0.0369 0.0626
Echinococcus multilocularis neuroglian 0.0059 0.0341 0.0581
Giardia lamblia Kinase, CMGC CDK 0.022 0.2055 1
Trichomonas vaginalis protein kinase atn1, putative 0.0198 0.1824 0.8817
Echinococcus multilocularis tensin 0.0379 0.3749 0.639
Trypanosoma cruzi protein kinase, putative 0.0198 0.1824 0.8491
Giardia lamblia Protein 21.1 0.0198 0.1824 0.8709
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0379 0.3749 0.639
Schistosoma mansoni tyrosine kinase 0.0198 0.1824 0.3109
Loa Loa (eye worm) hypothetical protein 0.0379 0.3749 0.3749
Echinococcus multilocularis heat shock protein 70 0.0198 0.1824 0.3109
Echinococcus granulosus cyclin dependent kinase 5 0.022 0.2055 0.3487
Loa Loa (eye worm) TK/FER protein kinase 0.0577 0.5867 0.5867
Schistosoma mansoni protein kinase 0.0198 0.1824 0.3109
Echinococcus granulosus peroxidasin 0.0037 0.0097 0.0165
Loa Loa (eye worm) serine/threonine protein kinase 0.0198 0.1824 0.1824
Schistosoma mansoni protein kinase 0.0198 0.1824 0.3109
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0106 0.0035
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0198 0.1824 0.3094
Schistosoma mansoni protein kinase 0.0198 0.1824 0.3109
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0198 0.1824 0.1824
Onchocerca volvulus 0.0577 0.5867 0.6203
Loa Loa (eye worm) TK/DDR protein kinase 0.0198 0.1824 0.1824
Loa Loa (eye worm) hypothetical protein 0.0198 0.1824 0.1824
Echinococcus granulosus tyrosine protein kinase csk 0.0198 0.1824 0.3094
Brugia malayi Protein kinase domain containing protein 0.022 0.2051 0.2051
Loa Loa (eye worm) hypothetical protein 0.0198 0.1824 0.1824
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.1824 0.2787
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Toxoplasma gondii protein kinase domain-containing protein 0.0198 0.1824 0.8799
Loa Loa (eye worm) TK protein kinase 0.0198 0.1824 0.1824
Trichomonas vaginalis cyclin D, putative 0.0052 0.0262 0.0831
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0198 0.1824 0.8817
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0379 0.3749 0.3749
Echinococcus granulosus SH2 domain containing protein 7 0.0379 0.3749 0.6359
Entamoeba histolytica protein kinase, putative 0.0198 0.1824 0.2787
Loa Loa (eye worm) hypothetical protein 0.0047 0.0212 0.0212
Schistosoma mansoni cyclins 0.0052 0.0262 0.0446
Brugia malayi STAT protein, DNA binding domain containing protein 0.0379 0.3749 0.3749
Trichomonas vaginalis conserved hypothetical protein 0.0198 0.1824 0.8817
Loa Loa (eye worm) TK/FER protein kinase 0.0198 0.1824 0.1824
Loa Loa (eye worm) SH2 domain-containing protein 0.0379 0.3749 0.3749
Echinococcus multilocularis Immunoglobulin 0.0047 0.0212 0.0361
Loa Loa (eye worm) hypothetical protein 0.0379 0.3749 0.3749
Echinococcus granulosus expressed conserved protein 0.0379 0.3749 0.6359
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.1824 0.2787
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0379 0.3749 0.639
Brugia malayi Protein kinase domain containing protein 0.0198 0.1824 0.1824
Loa Loa (eye worm) SRC-1 0.0577 0.5867 0.5867
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0262 0.0831
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Schistosoma mansoni protein kinase 0.0198 0.1824 0.3109
Echinococcus granulosus fibroblast growth factor receptor 4 0.0198 0.1824 0.3094
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0201 0.1852 0.8946
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0201 0.1852 0.8676
Entamoeba histolytica protein kinase, putative 0.0198 0.1824 0.2787
Loa Loa (eye worm) TK/ABL protein kinase 0.0577 0.5867 0.5867
Loa Loa (eye worm) hypothetical protein 0.0037 0.0097 0.0097
Trichomonas vaginalis CMGC family protein kinase 0.022 0.2055 1
Brugia malayi SRC-1 0.0577 0.5867 0.5867
Loa Loa (eye worm) TK/FER protein kinase 0.0198 0.1824 0.1824
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0379 0.3749 0.639
Echinococcus granulosus tyrosine protein kinase ABL1 0.0577 0.5867 0.9952
Echinococcus granulosus cyclin dependent kinase 1 0.022 0.2055 0.3487
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.022 0.2055 0.2055
Echinococcus granulosus tyrosine kinase 0.0577 0.5867 0.9952
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0198 0.1824 0.1824
Entamoeba histolytica tyrosine kinase, putative 0.0198 0.1824 0.2787
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0119 0.0979 0.1668
Entamoeba histolytica protein kinase, putative 0.0198 0.1824 0.2787
Loa Loa (eye worm) hypothetical protein 0.0076 0.0521 0.0521
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Entamoeba histolytica serine/threonine kinase, putative 0.0198 0.1824 0.2787
Schistosoma mansoni protein tyrosine kinase 0.0198 0.1824 0.3109
Leishmania major protein kinase, putative 0.0198 0.1824 0.8491
Entamoeba histolytica cysteine surface protein, putative 0.0198 0.1824 0.2787
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0201 0.1852 0.3142
Brugia malayi Protein kinase domain containing protein 0.0198 0.1824 0.1824
Brugia malayi Receptor family ligand binding region containing protein 0.0198 0.1824 0.1824
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Loa Loa (eye worm) carbonic anhydrase 3 0.0119 0.0979 0.0979
Trypanosoma brucei protein kinase, putative 0.0201 0.1852 0.8676
Loa Loa (eye worm) TK/FER protein kinase 0.0577 0.5867 0.5867
Loa Loa (eye worm) hypothetical protein 0.0047 0.0212 0.0212
Echinococcus granulosus growth factor receptor bound protein 2 0.0379 0.3749 0.6359
Brugia malayi Furin-like cysteine rich region family protein 0.0198 0.1824 0.1824
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0198 0.1824 0.3094
Echinococcus granulosus natriuretic peptide receptor 1 0.0198 0.1824 0.3094
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0577 0.5867 0.9952
Entamoeba histolytica protein kinase, putative 0.0198 0.1824 0.2787
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0577 0.5867 0.9952
Onchocerca volvulus 0.0379 0.3749 0.3963
Echinococcus multilocularis 0.0379 0.3749 0.639
Onchocerca volvulus 0.0198 0.1824 0.1928
Loa Loa (eye worm) TK/ROR protein kinase 0.0232 0.218 0.218
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Trypanosoma cruzi protein kinase, putative 0.0198 0.1824 0.8491
Echinococcus multilocularis cyclins 0.0052 0.0262 0.0446
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0379 0.3749 0.639
Entamoeba histolytica protein kinase, putative 0.0198 0.1824 0.2787
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0379 0.3749 0.639
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0106 0.0035
Schistosoma mansoni tyrosine kinase 0.0577 0.5867 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0198 0.1824 0.2787
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0198 0.1824 0.8817
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0201 0.1852 0.8676
Schistosoma mansoni tyrosine protein kinase 0.0198 0.1824 0.3109
Echinococcus multilocularis signal transduction protein lnk realted 0.0379 0.3749 0.639
Entamoeba histolytica hypothetical protein 0.0198 0.1824 0.2787
Echinococcus granulosus SH2 motif 0.0379 0.3749 0.6359
Brugia malayi Protein kinase domain containing protein 0.0198 0.1824 0.1824
Brugia malayi Cyclin, N-terminal domain containing protein 0.0243 0.2305 0.2305
Brugia malayi Tyrosine-protein kinase PR2 0.0198 0.1824 0.1824
Onchocerca volvulus 0.0577 0.5867 0.6203
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Echinococcus multilocularis SH2 motif 0.0379 0.3749 0.639
Loa Loa (eye worm) TK/FER protein kinase 0.0577 0.5867 0.5867
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0198 0.1824 0.1928
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Trypanosoma brucei Pseudokinase, putative 0.0198 0.1824 0.8491
Schistosoma mansoni hypothetical protein 0.0379 0.3749 0.639
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0379 0.3749 0.6359
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.004 0.0134 0.0229
Echinococcus multilocularis cyclins 0.0052 0.0262 0.0446
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0052 0.0262 0.0446
Echinococcus multilocularis cyclin dependent kinase 0.022 0.2055 0.3503
Entamoeba histolytica hypothetical protein 0.0198 0.1824 0.2787
Brugia malayi Protein kinase domain containing protein 0.0577 0.5867 0.5867
Trypanosoma cruzi cdc2-related kinase 1 0.022 0.2055 1
Schistosoma mansoni tensin-related 0.0379 0.3749 0.639
Loa Loa (eye worm) hypothetical protein 0.0198 0.1824 0.1824
Entamoeba histolytica protein kinase domain containing protein 0.0201 0.1852 0.2837
Brugia malayi Protein kinase domain containing protein 0.0198 0.1824 0.1824
Entamoeba histolytica hypothetical protein, conserved 0.0198 0.1824 0.2787
Echinococcus multilocularis growth factor receptor bound protein 2 0.0379 0.3749 0.639
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0119 0.0979 0.0979
Entamoeba histolytica ankyrin repeat protein 0.0198 0.1824 0.2787
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Onchocerca volvulus 0.0076 0.0521 0.0551
Brugia malayi integrin-linked kinase 0.0198 0.1824 0.1824
Brugia malayi hypothetical protein 0.0198 0.1824 0.1824
Entamoeba histolytica serine/threonine kinase, putative 0.0198 0.1824 0.2787
Echinococcus granulosus N chimaerin 0.0379 0.3749 0.6359
Echinococcus granulosus NCK adaptor protein 0.0379 0.3749 0.6359
Loa Loa (eye worm) RGC/RGC protein kinase 0.0198 0.1824 0.1824
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Trypanosoma cruzi cdc2-related kinase 1 0.022 0.2055 1
Echinococcus multilocularis tyrosine protein kinase csk 0.0198 0.1824 0.3109
Brugia malayi Protein kinase domain containing protein 0.0198 0.1824 0.1824
Echinococcus granulosus cyclin B3 1 0.0052 0.0262 0.0444
Trichomonas vaginalis conserved hypothetical protein 0.0198 0.1824 0.8817
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0198 0.1824 0.2787
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Trypanosoma brucei carbonic anhydrase-like protein 0.0119 0.0979 0.2982
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Entamoeba histolytica tyrosine kinase, putative 0.0198 0.1824 0.2787
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0379 0.3749 0.639
Trypanosoma brucei cdc2-related kinase 3 0.022 0.2055 1
Onchocerca volvulus 0.0198 0.1824 0.1928
Brugia malayi Protein kinase domain containing protein 0.0577 0.5867 0.5867
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0577 0.5867 1
Entamoeba histolytica hypothetical protein 0.0198 0.1824 0.2787
Loa Loa (eye worm) hypothetical protein 0.0076 0.0521 0.0521
Schistosoma mansoni serine/threonine protein kinase 0.022 0.2055 0.3503
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0198 0.1824 0.2787
Echinococcus granulosus raf serine:threonine protein kinase 0.0198 0.1824 0.3094
Loa Loa (eye worm) hypothetical protein 0.0198 0.1824 0.1824
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0198 0.1824 0.1824
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Brugia malayi Cyclin, N-terminal domain containing protein 0.0076 0.0521 0.0521
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0577 0.5867 1
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.1824 0.2787
Brugia malayi Protein kinase domain containing protein 0.0198 0.1824 0.1824
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Echinococcus granulosus retinal guanylyl cyclase 2 0.0198 0.1824 0.3094
Echinococcus granulosus tyrosine protein kinase pr2 0.0198 0.1824 0.3094
Schistosoma mansoni SH2A 0.0379 0.3749 0.639
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0201 0.1852 0.3157
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0198 0.1824 0.3109
Brugia malayi SH2 domain containing protein 0.0379 0.3749 0.3749
Schistosoma mansoni tyrosine kinase 0.0198 0.1824 0.3109
Brugia malayi Protein kinase domain containing protein 0.0198 0.1824 0.1824
Echinococcus granulosus kinase suppressor of Ras 1 0.0198 0.1824 0.3094
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0198 0.1824 0.3109
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.022 0.2055 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0078 0.0078
Echinococcus multilocularis SH2 motif 0.0379 0.3749 0.639
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0198 0.1824 0.2787
Brugia malayi hypothetical protein 0.0047 0.0212 0.0212
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.1824 0.2787
Brugia malayi Variant SH3 domain containing protein 0.0379 0.3749 0.3749
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0198 0.1824 0.2787
Loa Loa (eye worm) hypothetical protein 0.0075 0.0506 0.0506
Trichomonas vaginalis TK family protein kinase 0.0198 0.1824 0.8817
Schistosoma mansoni ephrin receptor 0.0198 0.1824 0.3109
Brugia malayi Protein kinase domain containing protein 0.0198 0.1824 0.1824
Loa Loa (eye worm) TK/FER protein kinase 0.0577 0.5867 0.5867
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0198 0.1824 0.3109
Echinococcus granulosus retinal guanylyl cyclase 2 0.0198 0.1824 0.3094
Echinococcus multilocularis tyrosine protein kinase csk 0.0198 0.1824 0.3109
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0198 0.1824 0.1824
Echinococcus multilocularis tyrosine protein kinase Blk 0.0577 0.5867 1
Schistosoma mansoni protein kinase 0.0198 0.1824 0.3109
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Entamoeba histolytica tyrosine kinase, putative 0.0198 0.1824 0.2787
Echinococcus granulosus retinal guanylyl cyclase 2 0.0198 0.1824 0.3094
Loa Loa (eye worm) STAT protein 0.0379 0.3749 0.3749
Onchocerca volvulus 0.0198 0.1824 0.1928
Schistosoma mansoni tyrosine kinase 0.0198 0.1824 0.3109
Onchocerca volvulus 0.0198 0.1824 0.1928
Trypanosoma cruzi cdc2-related kinase 3 0.022 0.2055 1
Echinococcus granulosus neuroglian 0.0059 0.0341 0.0578
Loa Loa (eye worm) TK protein kinase 0.0198 0.1824 0.1824
Echinococcus multilocularis tyrosine kinase 0.0577 0.5867 1
Echinococcus multilocularis cyclin dependent kinase 1 0.022 0.2055 0.3503
Loa Loa (eye worm) SH2 domain-containing protein 0.0379 0.3749 0.3749
Schistosoma mansoni tyrosine kinase 0.0577 0.5867 1
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.021 0.1953 0.3329
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.1824 0.2787
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0198 0.1824 0.3109
Entamoeba histolytica tyrosine kinase, putative 0.0198 0.1824 0.2787
Schistosoma mansoni serine/threonine protein kinase 0.0198 0.1824 0.3109
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0379 0.3749 0.639
Loa Loa (eye worm) TK/FER protein kinase 0.0198 0.1824 0.1824
Schistosoma mansoni ephrin receptor 0.0198 0.1824 0.3109
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0119 0.0979 0.2982
Brugia malayi Variant SH3 domain containing protein 0.0379 0.3749 0.3749
Brugia malayi cytokine inducible SH2-containing protein 5 0.0379 0.3749 0.3749
Echinococcus granulosus receptor type guanylyl cyclase 0.0198 0.1824 0.3094
Entamoeba histolytica tyrosin kinase, putative 0.0198 0.1824 0.2787
Brugia malayi Cyclin, N-terminal domain containing protein 0.0076 0.0521 0.0521
Schistosoma mansoni GTPase activating protein 0.0379 0.3749 0.639
Entamoeba histolytica hypothetical protein 0.0198 0.1824 0.2787
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0198 0.1824 0.2787
Echinococcus granulosus tyrosine protein kinase csk 0.0198 0.1824 0.3094
Echinococcus granulosus cyclin B 0.0076 0.0521 0.0884
Echinococcus multilocularis natriuretic peptide receptor 1 0.0198 0.1824 0.3109
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0577 0.5867 1
Schistosoma mansoni tyrosine kinase 0.0198 0.1824 0.3109
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.1824 0.2787
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0577 0.5867 1
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0119 0.0979 0.0979
Trichomonas vaginalis conserved hypothetical protein 0.0198 0.1824 0.8817
Entamoeba histolytica protein kinase, putative 0.0198 0.1824 0.2787
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0119 0.0979 0.2982
Brugia malayi Protein kinase domain containing protein 0.0198 0.1824 0.1824
Loa Loa (eye worm) hypothetical protein 0.0198 0.1824 0.1824
Echinococcus granulosus tyrosine protein kinase Lyn 0.058 0.5895 1
Entamoeba histolytica tyrosine kinase, putative 0.0198 0.1824 0.2787
Echinococcus granulosus insulin receptor 0.0198 0.1824 0.3094
Echinococcus multilocularis FL cytokine receptor 0.0198 0.1824 0.3109
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.1824 0.2787
Schistosoma mansoni serine/threonine RGC 0.0198 0.1824 0.3109
Echinococcus granulosus hypothetical protein 0.0379 0.3749 0.6359
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0379 0.3749 0.639
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0117 0.0953 0.1624
Echinococcus granulosus tyrosine protein kinase Blk 0.0577 0.5867 0.9952
Loa Loa (eye worm) TK/FER protein kinase 0.0198 0.1824 0.1824
Brugia malayi SH2 domain containing protein 0.0379 0.3749 0.3749
Echinococcus multilocularis NCK adaptor protein 0.0379 0.3749 0.639
Brugia malayi Variant SH3 domain containing protein 0.0379 0.3749 0.3749
Echinococcus granulosus activin receptor type 0.0201 0.1852 0.3142
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0379 0.3749 0.6359
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.1824 0.2787
Loa Loa (eye worm) hypothetical protein 0.0379 0.3749 0.3749
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0198 0.1824 0.3109
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0063 0.0377 0.0639
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0577 0.5867 1
Loa Loa (eye worm) hypothetical protein 0.0379 0.3749 0.3749
Schistosoma mansoni serine/threonine protein kinase 0.022 0.2055 0.3503
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0577 0.5867 1
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0379 0.3749 0.3749
Echinococcus multilocularis c src tyrosine kinase 0.0577 0.5867 1
Schistosoma mansoni protein kinase 0.0201 0.1852 0.3157
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Loa Loa (eye worm) TK/FAK protein kinase 0.0388 0.3846 0.3846
Trichomonas vaginalis cyclins, putative 0.0076 0.0521 0.2156
Loa Loa (eye worm) hypothetical protein 0.0379 0.3749 0.3749
Entamoeba histolytica hypothetical protein 0.0207 0.1921 0.296
Echinococcus multilocularis cyclins 0.0052 0.0262 0.0446
Trichomonas vaginalis cyclin B, putative 0.0052 0.0262 0.0831
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0198 0.1824 0.8817
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0379 0.3749 0.639
Schistosoma mansoni tensin 0.0379 0.3749 0.639
Loa Loa (eye worm) TK/INSR protein kinase 0.0198 0.1824 0.1824
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0198 0.1824 0.1824
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.1824 0.2787
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Echinococcus multilocularis tyrosine protein kinase csk 0.0198 0.1824 0.3109
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Brugia malayi Protein kinase domain containing protein 0.0198 0.1824 0.1824
Echinococcus granulosus roundabout 2 0.0075 0.0506 0.0858
Brugia malayi Sex muscle abnormal protein 5 0.0379 0.3749 0.3749
Echinococcus multilocularis cyclin dependent kinase 1 0.022 0.2055 0.3503
Loa Loa (eye worm) hypothetical protein 0.0379 0.3749 0.3749
Echinococcus multilocularis activated cdc42 kinase 1 0.0198 0.1824 0.3109
Loa Loa (eye worm) hypothetical protein 0.0117 0.0953 0.0953
Brugia malayi cell division control protein 2 homolog 0.022 0.2055 0.2055
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0052 0.0262 0.0444
Loa Loa (eye worm) RGC/RGC protein kinase 0.0198 0.1824 0.1824
Echinococcus granulosus tyrosine protein kinase Fyn 0.0577 0.5867 0.9952
Brugia malayi ephrin receptor 1 precursor 0.0198 0.1824 0.1824
Entamoeba histolytica protein kinase, putative 0.0198 0.1824 0.2787
Echinococcus multilocularis tensin 0.0379 0.3749 0.639
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0198 0.1824 0.3109
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0198 0.1824 0.1824
Brugia malayi Cyclin, N-terminal domain containing protein 0.0052 0.0262 0.0262
Plasmodium vivax protein kinase Crk2 0.022 0.2055 1
Echinococcus granulosus cyclin b3 0.0052 0.0262 0.0444
Entamoeba histolytica tyrosin kinase, putative 0.0198 0.1824 0.2787
Loa Loa (eye worm) TK/FER protein kinase 0.0577 0.5867 0.5867
Entamoeba histolytica hypothetical protein 0.0198 0.1824 0.2787
Schistosoma mansoni tyrosine kinase 0.0198 0.1824 0.3109
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0379 0.3749 0.3749
Schistosoma mansoni nck2/grb4 0.0379 0.3749 0.639
Loa Loa (eye worm) TK/Met protein kinase 0.0198 0.1824 0.1824
Schistosoma mansoni tyrosine kinase 0.0198 0.1824 0.3109
Echinococcus multilocularis p2X purinoceptor 4 0.0378 0.3745 0.6384
Trichomonas vaginalis cyclin B, putative 0.0076 0.0521 0.2156
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Schistosoma mansoni vesicular amine transporter 0.005 0.024 0.0409
Loa Loa (eye worm) hypothetical protein 0.0379 0.3749 0.3749
Brugia malayi Protein kinase domain containing protein 0.0198 0.1824 0.1824
Giardia lamblia G2/mitotic-specific cyclin B 0.0076 0.0521 0.1446
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0198 0.1824 0.1824
Entamoeba histolytica tyrosin kinase, putative 0.0198 0.1824 0.2787
Echinococcus granulosus tyrosine protein kinase 0.0198 0.1824 0.3094
Entamoeba histolytica protein kinase, putative 0.0198 0.1824 0.2787
Entamoeba histolytica protein kinase, putative 0.0198 0.1824 0.2787
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0577 0.5867 1
Brugia malayi SH2 domain containing protein 0.0379 0.3749 0.3749
Loa Loa (eye worm) TK/FER protein kinase 0.0198 0.1824 0.1824
Schistosoma mansoni protein kinase 0.0198 0.1824 0.3109
Brugia malayi Protein kinase domain containing protein 0.0198 0.1824 0.1824
Loa Loa (eye worm) hypothetical protein 0.0198 0.1824 0.1824
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0198 0.1824 0.3109
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0198 0.1824 0.3094
Entamoeba histolytica tyrosine kinase, putative 0.0198 0.1824 0.2787
Brugia malayi C-terminal src kinase protein 1 0.0198 0.1824 0.1824
Loa Loa (eye worm) hypothetical protein 0.0063 0.0377 0.0377
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0198 0.1824 0.2787
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Echinococcus granulosus c src tyrosine kinase 0.0577 0.5867 0.9952
Loa Loa (eye worm) hypothetical protein 0.0217 0.2027 0.2027
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0198 0.1824 0.1824
Trichomonas vaginalis cyclin A, putative 0.0076 0.0521 0.2156
Onchocerca volvulus 0.0379 0.3749 0.3963
Echinococcus granulosus tyrosine protein kinase csk 0.0198 0.1824 0.3094
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Echinococcus multilocularis tyrosine protein kinase 0.0198 0.1824 0.3109
Echinococcus granulosus defective proboscis extension response 0.0047 0.0212 0.0359
Schistosoma mansoni cyclin B3 0.0052 0.0262 0.0446
Echinococcus granulosus activated cdc42 kinase 1 0.0198 0.1824 0.3094
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Echinococcus multilocularis SH2 domain containing protein 7 0.0379 0.3749 0.639
Loa Loa (eye worm) hypothetical protein 0.0198 0.1824 0.1824
Onchocerca volvulus 0.0577 0.5867 0.6203
Onchocerca volvulus 0.0198 0.1824 0.1928
Loa Loa (eye worm) TK protein kinase 0.0198 0.1824 0.1824
Echinococcus granulosus tyrosine kinase 0.0198 0.1824 0.3094
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0198 0.1824 0.3094
Brugia malayi Protein kinase domain containing protein 0.0577 0.5867 0.5867
Entamoeba histolytica hypothetical protein 0.0198 0.1824 0.2787
Loa Loa (eye worm) hypothetical protein 0.0379 0.3749 0.3749
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0379 0.3749 0.3963
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0047 0.0212 0.0361
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0047 0.0212 0.0361
Entamoeba histolytica protein kinase, putative 0.0198 0.1824 0.2787
Brugia malayi Protein kinase domain containing protein 0.0198 0.1824 0.1824
Loa Loa (eye worm) protein kinase domain-containing protein 0.0198 0.1824 0.1824
Entamoeba histolytica tyrosine kinase, putative 0.0198 0.1824 0.2787
Echinococcus granulosus Immunoglobulin 0.0047 0.0212 0.0359
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0198 0.1824 0.3109
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.022 0.2055 0.3487
Echinococcus multilocularis peroxidasin 0.0037 0.0097 0.0166
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.004 0.0134 0.0134
Brugia malayi Protein kinase domain containing protein 0.0198 0.1824 0.1824
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0198 0.1824 0.8491
Schistosoma mansoni nephrin 0.0059 0.0341 0.0581
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0198 0.1824 0.8799
Echinococcus multilocularis transfer RNA-Thr 0.0198 0.1824 0.3109
Trichomonas vaginalis cyclin B, putative 0.0076 0.0521 0.2156
Echinococcus granulosus tyrosine protein kinase HCK 0.0198 0.1824 0.3094
Onchocerca volvulus 0.0117 0.0953 0.1007
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0198 0.1824 0.1824
Brugia malayi hypothetical protein 0.0577 0.5867 0.5867
Entamoeba histolytica tyrosine kinase, putative 0.0198 0.1824 0.2787
Trichomonas vaginalis STE family protein kinase 0.0198 0.1824 0.8817
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0577 0.5867 0.9952
Brugia malayi SH2 domain containing protein 0.0577 0.5867 0.5867
Loa Loa (eye worm) TK/EPH protein kinase 0.0198 0.1824 0.1824
Onchocerca volvulus 0.0577 0.5867 0.6203
Schistosoma mansoni protein kinase 0.0198 0.1824 0.3109
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.1824 0.2787
Onchocerca volvulus Tyrosine kinase homolog 0.0913 0.9458 1
Echinococcus granulosus p2X purinoceptor 4 0.0378 0.3745 0.6353
Loa Loa (eye worm) hypothetical protein 0.0379 0.3749 0.3749
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0198 0.1824 0.3109
Echinococcus multilocularis ephrin type A receptor 4 A 0.0198 0.1824 0.3109
Entamoeba histolytica serine/threonine kinase, putative 0.0198 0.1824 0.2787
Brugia malayi Protein kinase domain containing protein 0.0198 0.1824 0.1824
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0198 0.1824 0.3109
Echinococcus multilocularis protein kinase 0.0198 0.1824 0.3109
Plasmodium falciparum protein kinase, putative 0.0198 0.1824 0.8709
Onchocerca volvulus 0.0198 0.1824 0.1928
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0198 0.1824 0.3109
Echinococcus granulosus carbonic anhydrase II 0.0119 0.0979 0.166
Brugia malayi Variant SH3 domain containing protein 0.0379 0.3749 0.3749
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0198 0.1824 0.2787
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0577 0.5867 1
Echinococcus granulosus ephrin type A receptor 4 A 0.0198 0.1824 0.3094
Loa Loa (eye worm) hypothetical protein 0.0577 0.5867 0.5867
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Loa Loa (eye worm) TK/ALK protein kinase 0.0198 0.1824 0.1824
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0198 0.1824 0.3109
Echinococcus granulosus tyrosine protein kinase Src42A 0.0379 0.3749 0.6359
Trichomonas vaginalis cyclins, putative 0.0052 0.0262 0.0831
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0198 0.1824 0.2787
Schistosoma mansoni hypothetical protein 0.0379 0.3749 0.639
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0379 0.3749 0.639
Trichomonas vaginalis cyclin B, putative 0.0076 0.0521 0.2156
Loa Loa (eye worm) TK protein kinase 0.0198 0.1824 0.1824
Trichomonas vaginalis conserved hypothetical protein 0.0198 0.1824 0.8817
Onchocerca volvulus 0.0198 0.1824 0.1928
Schistosoma mansoni P2X receptor subunit 0.0378 0.3745 0.6384
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0198 0.1824 0.3109
Schistosoma mansoni suppressor of cytokine signaling 0.0379 0.3749 0.639
Echinococcus granulosus suppressor of cytokine signaling 6 0.0379 0.3749 0.6359
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.1824 0.2787
Brugia malayi Protein kinase domain containing protein 0.022 0.2055 0.2055
Brugia malayi Guanylyl cyclase protein 23 0.0198 0.1824 0.1824
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Leishmania major carbonic anhydrase-like protein 0.0119 0.0979 0.2982
Giardia lamblia Kinase, NEK 0.0198 0.1824 0.8709
Echinococcus multilocularis insulin receptor 0.0198 0.1824 0.3109
Onchocerca volvulus 0.0106 0.0842 0.089
Trichomonas vaginalis conserved hypothetical protein 0.0198 0.1824 0.8817
Schistosoma mansoni suppressor of cytokine signaling 0.0379 0.3749 0.639
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.1824 0.2787
Loa Loa (eye worm) TK/FER protein kinase 0.0198 0.1824 0.1824
Brugia malayi hypothetical protein 0.0379 0.3749 0.3749
Echinococcus granulosus cyclins 0.0052 0.0262 0.0444
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0198 0.1824 0.1824
Echinococcus granulosus tyrosine protein kinase Src42A 0.0577 0.5867 0.9952
Plasmodium falciparum tyrosine kinase-like protein 0.0198 0.1824 0.8709
Loa Loa (eye worm) TK/FER protein kinase 0.0577 0.5867 0.5867
Echinococcus multilocularis kinase suppressor of Ras 1 0.0198 0.1824 0.3109
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0198 0.1824 0.8799
Brugia malayi Immunoglobulin I-set domain containing protein 0.0047 0.0212 0.0212
Echinococcus multilocularis tyrosine protein kinase pr2 0.0198 0.1824 0.3109
Echinococcus multilocularis cyclins 0.0052 0.0262 0.0446
Loa Loa (eye worm) hypothetical protein 0.0379 0.3749 0.3749
Entamoeba histolytica tyrosine kinase, putative 0.0198 0.1824 0.2787
Loa Loa (eye worm) TK/EGFR protein kinase 0.0198 0.1824 0.1824
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.003 0.0028 0.0028
Echinococcus granulosus activated cdc42 kinase 1 0.0198 0.1824 0.3094
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0198 0.1824 0.2787
Echinococcus multilocularis tyrosine protein kinase Abl 0.0577 0.5867 1
Echinococcus granulosus tensin 0.0379 0.3749 0.6359
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.022 0.2055 0.2055
Entamoeba histolytica receptor protein kinase, putative 0.0198 0.1824 0.2787
Schistosoma mansoni tyrosine kinase 0.0577 0.5867 1
Schistosoma mansoni tyrosine kinase 0.0198 0.1824 0.3109
Loa Loa (eye worm) TK/FER protein kinase 0.0198 0.1824 0.1824
Loa Loa (eye worm) TK/FER protein kinase 0.0577 0.5867 0.5867
Onchocerca volvulus 0.0379 0.3749 0.3963
Trichomonas vaginalis cyclins, putative 0.0076 0.0521 0.2156
Entamoeba histolytica serine/threonine kinase, putative 0.0198 0.1824 0.2787
Loa Loa (eye worm) hypothetical protein 0.0117 0.0953 0.0953
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.1824 0.2787
Schistosoma mansoni shc transforming protein 0.0379 0.3749 0.639
Loa Loa (eye worm) TK/RYK protein kinase 0.0198 0.1824 0.1824
Schistosoma mansoni P2X receptor subunit 0.0378 0.3745 0.6384
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0577 0.5867 0.9952
Brugia malayi Protein kinase domain containing protein 0.0198 0.1824 0.1824
Loa Loa (eye worm) TK/FER protein kinase 0.0577 0.5867 0.5867
Loa Loa (eye worm) RGC/RGC protein kinase 0.0198 0.1824 0.1824
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Schistosoma mansoni tyrosine kinase 0.0198 0.1824 0.3109
Toxoplasma gondii protein kinase 0.0198 0.1824 0.8799
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0198 0.1824 0.2787
Loa Loa (eye worm) TK protein kinase 0.021 0.1953 0.1953
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0207 0.1921 0.296
Brugia malayi hypothetical protein 0.0198 0.1824 0.1824
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Trichomonas vaginalis cyclin B, putative 0.0076 0.0521 0.2156
Entamoeba histolytica serine/threonine kinase, putative 0.0198 0.1824 0.2787
Trichomonas vaginalis AGC family protein kinase 0.0198 0.1824 0.8817
Entamoeba histolytica cyclin, putative 0.0076 0.0521 0.0463
Entamoeba histolytica protein kinase, putative 0.0381 0.3777 0.6272
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.022 0.2055 1
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0198 0.1824 0.3109
Entamoeba histolytica protein kinase, putative 0.0198 0.1824 0.2787
Entamoeba histolytica protein kinase, putative 0.0198 0.1824 0.2787
Brugia malayi Peroxidasin 0.0037 0.0097 0.0097
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0198 0.1824 0.2787
Plasmodium falciparum protein kinase 5 0.022 0.2055 1
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Trichomonas vaginalis CAMK family protein kinase 0.0198 0.1824 0.8817
Echinococcus multilocularis tyrosine protein kinase Srms 0.0577 0.5867 1
Loa Loa (eye worm) TK protein kinase 0.0198 0.1824 0.1824
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0379 0.3749 0.639
Entamoeba histolytica tyrosine kinase, putative 0.0198 0.1824 0.2787
Brugia malayi Protein kinase domain containing protein 0.0198 0.1824 0.1824
Loa Loa (eye worm) hypothetical protein 0.0198 0.1824 0.1824
Echinococcus granulosus cyclins 0.0052 0.0262 0.0444
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Echinococcus multilocularis cyclin B3 1 0.0052 0.0262 0.0446
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0198 0.1824 0.3094
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.1824 0.2787
Schistosoma mansoni serine/threonine protein kinase 0.0198 0.1824 0.3109
Echinococcus multilocularis cyclins 0.0052 0.0262 0.0446
Schistosoma mansoni tyrosine kinase 0.0577 0.5867 1
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0379 0.3749 0.3963
Trichomonas vaginalis CMGC family protein kinase 0.022 0.2055 1
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0198 0.1824 0.1824
Schistosoma mansoni protein kinase 0.0198 0.1824 0.3109
Echinococcus granulosus cyclins 0.0052 0.0262 0.0444
Echinococcus multilocularis epidermal growth factor receptor 0.0198 0.1824 0.3109
Entamoeba histolytica cell division protein kinase 2, putative 0.022 0.2055 0.32
Brugia malayi Protein kinase domain containing protein 0.0577 0.5867 0.5867
Brugia malayi Protein kinase domain containing protein 0.0198 0.1824 0.1824
Echinococcus granulosus p2X purinoceptor 4 0.0378 0.3745 0.6353
Schistosoma mansoni tyrosine kinase 0.0198 0.1824 0.3109
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.1824 0.2787
Echinococcus granulosus protein kinase 0.0198 0.1824 0.3094
Schistosoma mansoni vav2 0.0379 0.3749 0.639
Loa Loa (eye worm) hypothetical protein 0.0379 0.3749 0.3749
Schistosoma mansoni cyclin B 0.0076 0.0521 0.0888
Onchocerca volvulus 0.0379 0.3749 0.3963
Schistosoma mansoni tyrosine kinase 0.0198 0.1824 0.3109
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0198 0.1824 0.2787
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Echinococcus multilocularis tyrosine protein kinase shark 0.0577 0.5867 1
Echinococcus granulosus epidermal growth factor receptor 0.0198 0.1824 0.3094
Entamoeba histolytica SH2 domain containing protein 0.0379 0.3749 0.6221
Trichomonas vaginalis conserved hypothetical protein 0.0198 0.1824 0.8817
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0198 0.1824 0.3094
Schistosoma mansoni P2X receptor subunit 0.0378 0.3745 0.6384
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.004 0.0134 0.0134
Schistosoma mansoni serine/threonine protein kinase 0.0198 0.1824 0.3109
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0198 0.1824 0.3109
Brugia malayi Protein kinase domain containing protein 0.0198 0.1824 0.1824
Onchocerca volvulus 0.0577 0.5867 0.6203
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0379 0.3749 0.3749
Plasmodium falciparum protein kinase, putative 0.0198 0.1824 0.8709
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Entamoeba histolytica protein kinase, putative 0.0198 0.1824 0.2787
Schistosoma mansoni tyrosine kinase 0.0386 0.3822 0.6515
Brugia malayi Protein kinase domain containing protein 0.0198 0.1824 0.1824
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0379 0.3749 0.6359
Schistosoma mansoni tyrosine kinase 0.0198 0.1824 0.3109
Schistosoma mansoni tyrosine kinase 0.0226 0.2118 0.361
Echinococcus multilocularis p2X purinoceptor 4 0.0378 0.3745 0.6384
Schistosoma mansoni tyrosine kinase 0.0198 0.1824 0.3109
Entamoeba histolytica hypothetical protein 0.0207 0.1921 0.296
Schistosoma mansoni adapter molecule crk 0.0379 0.3749 0.639
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0047 0.0212 0.0361
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0577 0.5867 1
Entamoeba histolytica ankyrin repeat protein 0.0198 0.1824 0.2787
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0174 0.0296
Entamoeba histolytica serine/threonine kinase, putative 0.0198 0.1824 0.2787
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0198 0.1824 0.2787
Brugia malayi SH2 domain containing protein 0.0577 0.5867 0.5867
Echinococcus multilocularis p2X purinoceptor 4 0.0378 0.3745 0.6384
Schistosoma mansoni growth factor receptor-bound protein 0.0379 0.3749 0.639
Onchocerca volvulus 0.0198 0.1824 0.1928
Plasmodium falciparum protein kinase, putative 0.0201 0.1852 0.8867
Echinococcus multilocularis tyrosine kinase 0.0198 0.1824 0.3109
Loa Loa (eye worm) hypothetical protein 0.0198 0.1824 0.1824
Schistosoma mansoni serine/threonine protein kinase 0.0198 0.1824 0.3109
Entamoeba histolytica protein kinase, putative 0.0198 0.1824 0.2787
Entamoeba histolytica tyrosine kinase, putative 0.0198 0.1824 0.2787
Echinococcus granulosus SH2 motif 0.0379 0.3749 0.6359
Echinococcus granulosus tyrosine protein kinase Src64B 0.0577 0.5867 0.9952
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0379 0.3749 0.639
Schistosoma mansoni tyrosine kinase 0.0198 0.1824 0.3109
Schistosoma mansoni P2X receptor subunit 0.0378 0.3745 0.6384
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.1824 0.2787
Brugia malayi SH2 domain containing protein 0.0379 0.3749 0.3749
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0577 0.5867 1
Echinococcus granulosus SHC transforming protein 3 0.0379 0.3749 0.6359
Entamoeba histolytica hypothetical protein 0.0198 0.1824 0.2787
Trichomonas vaginalis cyclin D, putative 0.0052 0.0262 0.0831
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.1824 0.2787
Leishmania major protein kinase, putative 0.0201 0.1852 0.8676
Loa Loa (eye worm) TK/FER protein kinase 0.0577 0.5867 0.5867
Echinococcus multilocularis tyrosine protein kinase HCK 0.0198 0.1824 0.3109
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0381 0.3777 0.6272
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0379 0.3749 0.6359
Schistosoma mansoni growth factor receptor-bound protein 0.0379 0.3749 0.639
Entamoeba histolytica tyrosine kinase, putative 0.0198 0.1824 0.2787
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0198 0.1824 0.3094
Echinococcus granulosus cyclin dependent kinase 0.022 0.2055 0.3487
Loa Loa (eye worm) hypothetical protein 0.0075 0.0506 0.0506
Loa Loa (eye worm) TK/CSK protein kinase 0.0198 0.1824 0.1824
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0379 0.3749 0.3749
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0198 0.1824 0.3094
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0198 0.1824 0.3094
Trichomonas vaginalis protein tyrosine kinase, putative 0.0198 0.1824 0.8817
Onchocerca volvulus 0.0577 0.5867 0.6203
Loa Loa (eye worm) TK protein kinase 0.0577 0.5867 0.5867
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0198 0.1824 0.3109
Plasmodium falciparum tyrosine kinase-like protein 0.0198 0.1824 0.8709
Entamoeba histolytica protein kinase, putative 0.0198 0.1824 0.2787
Loa Loa (eye worm) TK protein kinase 0.0198 0.1824 0.1824
Brugia malayi Protein kinase domain containing protein 0.0198 0.1824 0.1824
Entamoeba histolytica hypothetical protein 0.0207 0.1921 0.296
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0198 0.1824 0.3094
Loa Loa (eye worm) hypothetical protein 0.0047 0.0212 0.0212
Echinococcus granulosus SH2 domain containing adapter protein F 0.0379 0.3749 0.6359
Entamoeba histolytica tyrosine kinase, putative 0.0198 0.1824 0.2787
Entamoeba histolytica tyrosin kinase, putative 0.0198 0.1824 0.2787
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Echinococcus multilocularis integrin linked protein kinase 0.0198 0.1824 0.3109
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Echinococcus multilocularis receptor type guanylyl cyclase 0.0198 0.1824 0.3109
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0198 0.1824 0.1824
Loa Loa (eye worm) hypothetical protein 0.0198 0.1824 0.1824
Giardia lamblia Kinase, CMGC CDK 0.022 0.2055 1
Entamoeba histolytica tyrosine kinase, putative 0.0198 0.1824 0.2787
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Loa Loa (eye worm) hypothetical protein 0.0379 0.3749 0.3749
Echinococcus multilocularis cyclins 0.0052 0.0262 0.0446
Loa Loa (eye worm) cyclin domain-containing protein 0.0243 0.2305 0.2305
Entamoeba histolytica protein kinase, putative 0.0198 0.1824 0.2787
Entamoeba histolytica protein kinase, putative 0.0207 0.1921 0.296
Echinococcus multilocularis roundabout 2 0.0075 0.0506 0.0862
Echinococcus multilocularis protein tyrosine kinase 0.0386 0.3822 0.6515
Echinococcus granulosus tyrosine protein kinase Srms 0.0577 0.5867 0.9952
Loa Loa (eye worm) hypothetical protein 0.0198 0.1824 0.1824
Echinococcus multilocularis Immunoglobulin 0.0047 0.0212 0.0361
Echinococcus granulosus tyrosine protein kinase Fyn 0.0577 0.5867 0.9952
Schistosoma mansoni signal transduction protein lnk-related 0.0379 0.3749 0.639
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0201 0.1852 0.8676
Loa Loa (eye worm) hypothetical protein 0.0379 0.3749 0.3749
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0198 0.1824 0.2787
Echinococcus multilocularis raf serine:threonine protein kinase 0.0198 0.1824 0.3109
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Schistosoma mansoni tyrosine kinase 0.0198 0.1824 0.3109
Onchocerca volvulus 0.0703 0.7211 0.7624
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0379 0.3749 0.639
Echinococcus multilocularis cyclin b3 0.0052 0.0262 0.0446
Schistosoma mansoni tyrosine kinase 0.0198 0.1824 0.3109
Brugia malayi SH2 domain containing protein 0.0379 0.3749 0.3749
Schistosoma mansoni tyrosine kinase 0.0198 0.1824 0.3109
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0198 0.1824 0.3109
Brugia malayi SH2 domain containing protein 0.0379 0.3749 0.3749
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Brugia malayi Raf kinase 0.0198 0.1824 0.1824
Schistosoma mansoni protein kinase 0.0201 0.1852 0.3157
Brugia malayi Protein kinase domain containing protein 0.0388 0.3846 0.3846
Echinococcus granulosus tyrosine protein kinase Fyn 0.0577 0.5867 0.9952
Echinococcus granulosus protein tyrosine kinase 0.0386 0.3822 0.6484
Echinococcus granulosus signal transduction protein lnk realted 0.0379 0.3749 0.6359
Entamoeba histolytica hypothetical protein 0.0198 0.1824 0.2787
Trichomonas vaginalis CMGC family protein kinase 0.022 0.2055 1
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0198 0.1824 0.1928
Trypanosoma brucei Flagellum attachment zone protein 20 0.0198 0.1824 0.8491
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.1824 0.2787
Entamoeba histolytica tyrosine kinase, putative 0.0198 0.1824 0.2787
Onchocerca volvulus 0.0379 0.3749 0.3963
Loa Loa (eye worm) TK/ACK protein kinase 0.0198 0.1824 0.1824
Echinococcus multilocularis cyclin B 0.0076 0.0521 0.0888
Entamoeba histolytica tyrosine kinase, putative 0.0198 0.1824 0.2787
Echinococcus granulosus cyclins 0.0052 0.0262 0.0444
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0379 0.3749 0.639
Echinococcus granulosus cyclins 0.0052 0.0262 0.0444
Echinococcus multilocularis carbonic anhydrase II 0.0119 0.0979 0.1668
Loa Loa (eye worm) TK protein kinase 0.0198 0.1824 0.1824
Brugia malayi tRNA modification GTPase TrmE family protein 0.0379 0.3749 0.3749
Brugia malayi Trypsin family protein 0.0117 0.0953 0.0953
Brugia malayi Tyrosine-protein kinase abl-1 0.0577 0.5867 0.5867
Loa Loa (eye worm) TK/FER protein kinase 0.0577 0.5867 0.5867
Loa Loa (eye worm) hypothetical protein 0.0047 0.0212 0.0212
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0577 0.5867 0.9952
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0577 0.5867 1
Schistosoma mansoni tensin 0.0379 0.3749 0.639
Echinococcus multilocularis cyclins 0.0052 0.0262 0.0446
Loa Loa (eye worm) cyclin domain-containing protein 0.0052 0.0262 0.0262
Schistosoma mansoni tyrosine kinase 0.0198 0.1824 0.3109
Echinococcus granulosus epidermal growth factor receptor 0.0198 0.1824 0.3094
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0577 0.5867 1
Echinococcus multilocularis N chimaerin 0.0379 0.3749 0.639
Giardia lamblia Kinase 0.0198 0.1824 0.8709
Echinococcus multilocularis protein KINase family member (kin 25) 0.0198 0.1824 0.3109
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0577 0.5867 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.0212 0.0212
Onchocerca volvulus 0.0379 0.3749 0.3963
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0117 0.0953 0.1624
Brugia malayi protein-tyrosine kinase 0.0577 0.5867 0.5867
Echinococcus multilocularis tyrosine protein kinase csk 0.0198 0.1824 0.3109
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Leishmania major hypothetical protein, conserved 0.0198 0.1824 0.8491
Trypanosoma brucei cdc2-related kinase 1 0.022 0.2055 1
Loa Loa (eye worm) hypothetical protein 0.0379 0.3749 0.3749
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0964 1 1
Echinococcus multilocularis SHC transforming protein 3 0.0379 0.3749 0.639
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0198 0.1824 0.8817
Loa Loa (eye worm) hypothetical protein 0.0056 0.0309 0.0309
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.022 0.2055 0.2055
Toxoplasma gondii STE kinase 0.0198 0.1824 0.8799
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0119 0.0979 0.1668
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Trichomonas vaginalis cyclins, putative 0.0076 0.0521 0.2156
Brugia malayi SH2 domain containing protein 0.0379 0.3749 0.3749
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0119 0.0979 0.0979
Echinococcus multilocularis cyclin dependent kinase 5 0.022 0.2055 0.3503
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0379 0.3749 0.3749
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.022 0.2055 1
Echinococcus granulosus potassium voltage gated channel subfamily H 0.004 0.0134 0.0228
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.1824 0.2787
Trichomonas vaginalis conserved hypothetical protein 0.0198 0.1824 0.8817
Schistosoma mansoni tyrosine kinase 0.0577 0.5867 1
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0174 0.0296
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0198 0.1824 0.1824
Schistosoma mansoni tyrosine kinase 0.0198 0.1824 0.3109
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0379 0.3749 0.6359
Trichomonas vaginalis cyclin B3, putative 0.0052 0.0262 0.0831
Entamoeba histolytica receptor protein kinase, putative 0.0198 0.1824 0.2787
Schistosoma mansoni tensin-related 0.0379 0.3749 0.639
Entamoeba histolytica protein kinase, putative 0.0198 0.1824 0.2787
Trichomonas vaginalis TKL family protein kinase 0.0198 0.1824 0.8817
Loa Loa (eye worm) SH2 domain-containing protein 0.0379 0.3749 0.3749
Entamoeba histolytica protein kinase, putative 0.0198 0.1824 0.2787
Echinococcus multilocularis protein kinase 0.0198 0.1824 0.3109
Brugia malayi Protein kinase domain containing protein 0.0577 0.5867 0.5867
Echinococcus multilocularis epidermal growth factor receptor 0.0198 0.1824 0.3109
Brugia malayi Protein kinase domain containing protein 0.0198 0.1824 0.1824
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0379 0.3749 0.3749
Loa Loa (eye worm) TK protein kinase 0.0198 0.1824 0.1824
Trichomonas vaginalis cyclins, putative 0.0076 0.0521 0.2156
Echinococcus multilocularis SH2 motif 0.0379 0.3749 0.639
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.1824 0.2787
Brugia malayi Protein kinase domain containing protein 0.0198 0.1824 0.1824
Schistosoma mansoni hypothetical protein 0.0198 0.1824 0.3109
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0577 0.5867 1
Brugia malayi Tensin 0.0379 0.3749 0.3749
Entamoeba histolytica cell division protein kinase 2, putative 0.022 0.2055 0.32
Echinococcus multilocularis activin receptor type 0.0201 0.1852 0.3157
Schistosoma mansoni tyrosine kinase 0.0198 0.1824 0.3109
Schistosoma mansoni tyrosine kinase 0.0198 0.1824 0.3109
Brugia malayi Immunoglobulin I-set domain containing protein 0.021 0.1953 0.1953
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0198 0.1824 0.3109
Echinococcus granulosus tyrosine protein kinase shark 0.0577 0.5867 0.9952
Brugia malayi RhoGAP domain containing protein 0.0379 0.3749 0.3749

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 5.6 uM Inhibitory activity against thrombin ChEMBL. 9301673
Ki (binding) = 5.6 uM Inhibitory activity against thrombin ChEMBL. 9301673
Ki (binding) = 39 uM Inhibitory activity against trypsin ChEMBL. 9301673
Ki (binding) = 39 uM Inhibitory activity against trypsin ChEMBL. 9301673

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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