Detailed information for compound 173889

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 249.261 | Formula: C10H19NO6
  • H donors: 5 H acceptors: 5 LogP: -1.76 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCC(=O)N[C@@H]1OC(CO)C(C(C1O)O)O
  • InChi: 1S/C10H19NO6/c1-2-3-6(13)11-10-9(16)8(15)7(14)5(4-12)17-10/h5,7-10,12,14-16H,2-4H2,1H3,(H,11,13)/t5?,7?,8?,9?,10-/m1/s1
  • InChiKey: XOHMAPSXUCVOKP-YHWIHQMFSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0092 0.09 0.3249
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0019 0.0031 0.0022
Loa Loa (eye worm) hypothetical protein 0.0046 0.0352 0.0398
Brugia malayi Protein-tyrosine phosphatase 1 0.0019 0.0031 0.0015
Echinococcus multilocularis sex peptide receptor 0.0092 0.09 0.09
Echinococcus granulosus 7TM GPCR rhodopsin 0.0092 0.09 0.09
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0019 0.0031 0.0022
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0024 0.0024
Schistosoma mansoni amine GPCR 0.0092 0.09 0.09
Onchocerca volvulus 0.0045 0.0345 0.1205
Plasmodium falciparum geranylgeranyltransferase, putative 0.002 0.0045 0.1118
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Brugia malayi Nuclear hormone receptor E75 0.0046 0.0352 0.0391
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0046 0.0352 0.0352
Loa Loa (eye worm) hypothetical protein 0.0148 0.1561 0.1815
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0019 0.0031 0.0031
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0019 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0025 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0051 0.0417 0.0474
Onchocerca volvulus 0.0092 0.09 0.3249
Plasmodium vivax aspartyl proteinase, putative 0.0018 0.0018 0.0194
Loa Loa (eye worm) hypothetical protein 0.0045 0.0345 0.039
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0092 0.09 0.09
Brugia malayi larval opioid receptor 0.0092 0.09 0.1035
Brugia malayi hypothetical protein 0.0046 0.0352 0.0391
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0019 0.0031 0.0031
Echinococcus granulosus neuropeptide receptor A26 0.0092 0.09 0.09
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0018 0.0018
Onchocerca volvulus 0.0019 0.0031 0.0048
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0169
Schistosoma mansoni nuclear hormone receptor 0.0046 0.0352 0.0352
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0019 0.0031 0.0096
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0069 0.1961
Schistosoma mansoni sodium/chloride dependent transporter 0.0148 0.1561 0.1561
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0025 0.0107 1
Echinococcus multilocularis orexin receptor type 2 0.0092 0.09 0.09
Schistosoma mansoni zinc finger protein 0.0046 0.0352 0.0352
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0739 0.8541 0.8541
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0018 0.0018
Onchocerca volvulus 0.0019 0.0031 0.0048
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0157 0.0169
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0369 0.0369
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0078 0.0731 0.2796
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0019 0.0031 0.0022
Brugia malayi Cytochrome P450 family protein 0.0019 0.004 0.0025
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0656 0.0656
Onchocerca volvulus 0.0097 0.0959 0.3466
Schistosoma mansoni thyroid hormone receptor 0.0226 0.2474 0.2474
Echinococcus granulosus tachykinin peptides receptor 99D 0.0092 0.09 0.09
Onchocerca volvulus 0.0092 0.09 0.3249
Echinococcus multilocularis lamin 0.0029 0.0157 0.0157
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0155 0.0167
Echinococcus granulosus cpg binding protein 0.0064 0.0566 0.0566
Brugia malayi AKH receptor 0.0092 0.09 0.1035
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0369 0.0369
Brugia malayi hypothetical protein 0.0092 0.09 0.1035
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0018 0.0018 0.0007
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0092 0.09 0.1035
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0019 0.0031 0.0022
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.002 0.0045 0.0104
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.002 0.0045 0.0031
Brugia malayi steroid hormone receptor 0.0097 0.0959 0.1104
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0097 0.0959 0.0959
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0019 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Schistosoma mansoni biogenic amine receptor 0.0092 0.09 0.09
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0097 0.0959 0.0959
Brugia malayi hypothetical protein 0.0019 0.0031 0.0015
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0019 0.0031 0.0022
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0301 0.0301
Loa Loa (eye worm) carboxylesterase 0.0268 0.2978 0.3478
Echinococcus multilocularis 0.0019 0.0031 0.0031
Schistosoma mansoni sodium/chloride dependent transporter 0.0025 0.0107 0.0107
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0019 0.0031 0.0022
Echinococcus multilocularis sodium and chloride dependent glycine 0.0025 0.0107 0.0107
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.09 0.09
Brugia malayi hypothetical protein 0.0092 0.09 0.1035
Brugia malayi hypothetical protein 0.0092 0.09 0.1035
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0018 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0097 0.0959 0.111
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Onchocerca volvulus Bile acid receptor homolog 0.0247 0.2732 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0092 0.09 0.09
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0097 0.0959 0.1104
Loa Loa (eye worm) neuropeptide F receptor 0.0092 0.09 0.1041
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0046 0.0352 0.0352
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0369 0.0369
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0143 0.0143
Plasmodium falciparum plasmepsin V 0.0018 0.0018 0.0194
Leishmania major farnesyltransferase beta subunit 0.002 0.0045 0.0252
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Onchocerca volvulus 0.0019 0.0031 0.0048
Echinococcus granulosus peptide allatostatin:somatostatin 0.0092 0.09 0.09
Brugia malayi Dopamine receptor 0.0092 0.09 0.1035
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.002 0.0045 0.0104
Loa Loa (eye worm) latrophilin receptor protein 2 0.0068 0.0617 0.0709
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.002 0.0045 0.0031
Toxoplasma gondii aspartyl protease ASP3 0.0018 0.0018 0.0048
Schistosoma mansoni opsin-like receptor 0.0092 0.09 0.09
Toxoplasma gondii aspartyl protease ASP1 0.0018 0.0018 0.0048
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.09 0.09
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.002 0.0045 0.0031
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.09 0.09
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0046 0.0352 0.1229
Loa Loa (eye worm) hypothetical protein 0.0042 0.0301 0.0338
Plasmodium vivax amine transporter, putative 0.0025 0.0107 0.3274
Plasmodium falciparum plasmepsin X 0.0018 0.0018 0.0194
Loa Loa (eye worm) hypothetical protein 0.0097 0.0959 0.111
Loa Loa (eye worm) CXXC zinc finger family protein 0.0061 0.0525 0.0601
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0097 0.0959 0.0959
Brugia malayi Cytochrome P450 family protein 0.0019 0.004 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.09 0.09
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0095 0.0303
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0019 0.0031 0.0031
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0024 0.0406
Loa Loa (eye worm) hypothetical protein 0.0051 0.0417 0.0474
Loa Loa (eye worm) hypothetical protein 0.0046 0.0352 0.0398
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0092 0.09 0.09
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0068 0.0617 0.0617
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0078 0.0731 0.0731
Echinococcus granulosus mitogen activated protein kinase 0.0056 0.0466 0.0466
Mycobacterium ulcerans carboxylesterase, LipT 0.0045 0.0345 1
Leishmania major geranylgeranyltransferase, putative 0.002 0.0045 0.0252
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0019 0.0031 0.0031
Echinococcus granulosus g protein coupled receptor 0.0092 0.09 0.09
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Schistosoma mansoni biogenic amine receptor 0.0092 0.09 0.09
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0051 0.0417 0.0417
Schistosoma mansoni growth hormone secretagogue receptor 0.0092 0.09 0.09
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0078 0.0731 0.4747
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0019 0.0031 0.0031
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0019 0.0031 0.0015
Plasmodium falciparum plasmepsin VII 0.0018 0.0018 0.0194
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0019 0.0031 0.0031
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0019 0.0031 0.0015
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0092 0.09 0.09
Loa Loa (eye worm) hypothetical protein 0.0148 0.1561 0.1815
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0019 0.0031 0.0015
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0045 0.0345 0.0345
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.09 0.09
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0056 0.0466 0.2994
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0019 0.0031 0.0031
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0056 0.0466 0.2994
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0107 0.0104
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Loa Loa (eye worm) hypothetical protein 0.0045 0.0345 0.039
Trypanosoma brucei protein farnesyltransferase beta subunit 0.002 0.0045 0.0213
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0097 0.0959 0.0959
Brugia malayi Carboxylesterase family protein 0.0045 0.0345 0.0384
Plasmodium falciparum LCCL domain-containing protein 0.0042 0.0301 1
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0056 0.0466 0.0532
Plasmodium falciparum plasmepsin IX 0.0018 0.0018 0.0194
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0097 0.0959 0.0959
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0078 0.0731 0.2796
Loa Loa (eye worm) aspartyl protease 6 0.0018 0.0018 0.0007
Toxoplasma gondii aspartyl protease 0.0018 0.0018 0.0048
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Brugia malayi hypothetical protein 0.0019 0.0031 0.0015
Loa Loa (eye worm) histone methyltransferase 0.002 0.0044 0.0037
Echinococcus multilocularis allatostatin A receptor 0.0092 0.09 0.09
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0092 0.09 0.09
Loa Loa (eye worm) hypothetical protein 0.0078 0.0731 0.0843
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.09 0.09
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0019 0.0031 0.0031
Brugia malayi neuropeptide F receptor 0.0092 0.09 0.1035
Loa Loa (eye worm) hypothetical protein 0.0046 0.0352 0.0398
Schistosoma mansoni hypothetical protein 0.0732 0.8456 0.8456
Plasmodium vivax importin-beta 2, putative 0.003 0.0162 0.5188
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0056 0.0466 0.3891
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Echinococcus granulosus neuropeptide Y receptor 0.0092 0.09 0.09
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0019 0.0031 0.0031
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0024 0.0077
Brugia malayi Protein-tyrosine phosphatase 0.0019 0.0031 0.0015
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0018 0.0018 0.0048
Loa Loa (eye worm) hypothetical protein 0.0216 0.2363 0.2756
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0019 0.0031 0.0015
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0216 0.2363 0.2756
Schistosoma mansoni adenoreceptor 0.0092 0.09 0.09
Schistosoma mansoni lipoxygenase 0.0116 0.1185 0.1185
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0019 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Brugia malayi nuclear receptor RXR 0.0046 0.0352 0.0391
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0019 0.0031 0.0031
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0024 0.0007
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0656 0.0656
Toxoplasma gondii exonuclease III APE 0.0018 0.0024 0.0101
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0019 0.0031 0.0031
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0019 0.0031 0.0031
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0019 0.0031 0.0031
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0024 0.0024
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0019 0.0031 0.0022
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0097 0.0959 0.0959
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0097 0.0959 0.0959
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.002 0.0045 0.0104
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0019 0.0031 0.0015
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0019 0.0031 0.0015
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0092 0.09 0.09
Schistosoma mansoni cathepsin D (A01 family) 0.0018 0.0018 0.0018
Echinococcus granulosus importin subunit beta 1 0.003 0.0162 0.0162
Brugia malayi hypothetical protein 0.0092 0.09 0.1035
Brugia malayi hypothetical protein 0.0025 0.0107 0.0104
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Loa Loa (eye worm) hypothetical protein 0.0046 0.0352 0.0398
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.09 0.09
Echinococcus granulosus tar DNA binding protein 0.0072 0.0656 0.0656
Schistosoma mansoni alpha-1 adrenergic receptor 0.0092 0.09 0.09
Echinococcus granulosus carboxylesterase 5A 0.0268 0.2978 0.2978
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0019 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0046 0.0352 0.0398
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0092 0.09 0.09
Echinococcus multilocularis neuropeptide s receptor 0.0092 0.09 0.09
Loa Loa (eye worm) norepinephrine transporter 0.0148 0.1561 0.1815
Onchocerca volvulus 0.0031 0.0171 0.0564
Toxoplasma gondii hypothetical protein 0.0025 0.0107 0.081
Brugia malayi Carboxylesterase family protein 0.0045 0.0345 0.0384
Brugia malayi Doublecortin family protein 0.0042 0.0301 0.0332
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.09 0.09
Plasmodium vivax plasmepsin IV, putative 0.0018 0.0018 0.0194
Loa Loa (eye worm) nuclear receptor NHR-67 0.0046 0.0352 0.0398
Loa Loa (eye worm) hypothetical protein 0.0025 0.0107 0.0111
Echinococcus granulosus neuropeptide receptor 0.0092 0.09 0.09
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.002 0.0045 0.0038
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0051 0.0417 0.0474
Loa Loa (eye worm) hypothetical protein 0.0045 0.0345 0.039
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0216 0.2363 0.2751
Loa Loa (eye worm) doublecortin family protein 0.0042 0.0301 0.0338
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0739 0.8541 0.8541
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.09 0.09
Onchocerca volvulus 0.0092 0.09 0.3249
Schistosoma mansoni protein tyrosine phosphatase 0.0019 0.0031 0.0031
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0046 0.0352 0.0352
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Echinococcus granulosus ubiquinone biosynthesis monooxygenase COQ6 0.0017 0.0012 0.0012
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0097 0.0959 0.0959
Brugia malayi Latrophilin receptor protein 2 0.0068 0.0617 0.0703
Plasmodium vivax aspartyl proteinase, putative 0.0018 0.0018 0.0194
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Schistosoma mansoni ap endonuclease 0.0018 0.0024 0.0024
Echinococcus granulosus BC026374 protein S09 family 0.0045 0.0345 0.0345
Giardia lamblia Rab geranylgeranyltransferase 0.002 0.0045 0.029
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0019 0.0031 0.0015
Onchocerca volvulus 0.0019 0.0031 0.0048
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0019 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0031 0.0171 0.0186
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Schistosoma mansoni protein tyrosine phosphatase 0.0019 0.0031 0.0031
Echinococcus granulosus g-protein coupled receptor 0.0092 0.09 0.09
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.002 0.0045 0.0045
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.002 0.0045 0.1118
Schistosoma mansoni hypothetical protein 0.0092 0.09 0.09
Onchocerca volvulus 0.0045 0.0345 0.1205
Schistosoma mansoni histamine h1 receptor 0.0092 0.09 0.09
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0078 0.0731 0.0731
Echinococcus granulosus g protein coupled receptor 0.0092 0.09 0.09
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0007
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0069 0.1961
Schistosoma mansoni biogenic amine receptor 0.0092 0.09 0.09
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0019 0.0031 0.0015
Onchocerca volvulus 0.0019 0.0031 0.0048
Schistosoma mansoni hypothetical protein 0.0068 0.0617 0.0617
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0078 0.0731 0.0731
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0019 0.0031 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0097 0.0959 0.1104
Brugia malayi hypothetical protein 0.0051 0.0417 0.0468
Schistosoma mansoni steroid hormone receptor ad4bp 0.0097 0.0959 0.0959
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0162 0.0988
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0092 0.09 0.1035
Brugia malayi G-protein coupled receptor 0.0092 0.09 0.1035
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.002 0.0045 0.0104
Plasmodium vivax aspartyl protease, putative 0.0018 0.0018 0.0194
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0739 0.8541 0.8541
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0072 0.0656 0.0755
Leishmania major lanosterol synthase, putative 0.0126 0.1292 1
Echinococcus multilocularis fmrfamide receptor 0.0092 0.09 0.09
Brugia malayi photoreceptor-specific nuclear receptor 0.0097 0.0959 0.1104
Brugia malayi putative neuropeptide receptor 0.0092 0.09 0.1035
Onchocerca volvulus 4.1 G protein, putative homolog 0.0019 0.0031 0.0048
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Schistosoma mansoni hypothetical protein 0.0092 0.09 0.09
Schistosoma mansoni acetylcholinesterase 0.0045 0.0345 0.0345
Schistosoma mansoni neuropeptide receptor 0.0092 0.09 0.09
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0038
Brugia malayi Pre-SET motif family protein 0.0206 0.2237 0.2603
Echinococcus granulosus allatostatin A receptor 0.0092 0.09 0.09
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0019 0.0031 0.0031
Schistosoma mansoni lamin 0.0029 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0019 0.0031 0.0145
Echinococcus granulosus acetylcholinesterase 0.0268 0.2978 0.2978
Schistosoma mansoni hypothetical protein 0.0068 0.0617 0.0617
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0044 0.0044
Brugia malayi hypothetical protein 0.0042 0.0301 0.0332
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0097 0.0959 0.111
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0078 0.0731 0.5619
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0078 0.0731 0.0731
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Toxoplasma gondii hypothetical protein 0.0025 0.0107 0.081
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0092 0.09 0.09
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0019 0.0031 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0097 0.0959 0.1104
Brugia malayi nuclear receptor NHR-88 0.0097 0.0959 0.1104
Schistosoma mansoni myosin xvIII 0.0092 0.09 0.09
Schistosoma mansoni amine GPCR 0.0092 0.09 0.09
Echinococcus granulosus ubiquitin specific protease 41 0.0078 0.0731 0.0731
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0069 0.0066
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0369 0.0369
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0097 0.0959 0.1104
Loa Loa (eye worm) hypothetical protein 0.0051 0.0417 0.0474
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0019 0.0031 0.0031
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0019 0.0031 0.0096
Onchocerca volvulus 0.0148 0.1561 0.5684
Plasmodium falciparum plasmepsin VI 0.0018 0.0018 0.0194
Trichomonas vaginalis pten, drome, putative 0.0019 0.0031 0.0051
Loa Loa (eye worm) hypothetical protein 0.0046 0.0352 0.0398
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0171 0.0171
Loa Loa (eye worm) hypothetical protein 0.0068 0.0617 0.0709
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0024 0.0352
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0069 0.0373
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.002 0.0045 0.0045
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0018 0.0018
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0171 0.0171
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.002 0.0045 0.0277
Loa Loa (eye worm) hypothetical protein 0.0025 0.0107 0.0111
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.002 0.0045 0.0277
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.002 0.0045 0.029
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0268 0.2978 0.2978
Loa Loa (eye worm) hypothetical protein 0.0051 0.0417 0.0474
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0107 0.0104
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0097 0.0959 0.1104
Onchocerca volvulus 0.0092 0.09 0.3249
Plasmodium vivax multidomain scavenger receptor, putative 0.0042 0.0301 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0739 0.8541 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0092 0.09 0.1041
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0019 0.0031 0.0031
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.002 0.0045 0.0045
Brugia malayi nuclear receptor RXR 0.0051 0.0417 0.0468
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0018 0.0018
Onchocerca volvulus 0.0092 0.09 0.3249
Onchocerca volvulus 0.0019 0.0031 0.0048
Echinococcus granulosus nuclear receptor nhr 48 0.0046 0.0352 0.0352
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0097 0.0959 0.1104
Echinococcus granulosus hypothetical protein 0.0092 0.09 0.09
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0097 0.0959 0.1104
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0019 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0019 0.0031 0.0015
Loa Loa (eye worm) hypothetical protein 0.0046 0.0352 0.0398
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0019 0.0031 0.0031
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0092 0.09 0.09
Loa Loa (eye worm) hypothetical protein 0.0045 0.0345 0.039
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0097 0.0959 0.0959
Entamoeba histolytica Ran family GTPase 0.0022 0.0069 0.0634
Echinococcus granulosus ecdysone induced protein 78C 0.0097 0.0959 0.0959
Brugia malayi hypothetical protein 0.0092 0.09 0.1035
Echinococcus granulosus neuropeptides capa receptor 0.0092 0.09 0.09
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0092 0.09 0.09
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Echinococcus granulosus dro:myosuppressin receptor 0.0092 0.09 0.09
Onchocerca volvulus 0.0092 0.09 0.3249
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0097 0.0959 0.0959
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Loa Loa (eye worm) melatonin receptor type 1A 0.0092 0.09 0.1041
Trichomonas vaginalis ran, putative 0.0022 0.0069 0.02
Schistosoma mansoni neuropeptide F-like receptor 0.0092 0.09 0.09
Echinococcus granulosus fmrfamide receptor 0.0092 0.09 0.09
Echinococcus granulosus neuropeptide s receptor 0.0092 0.09 0.09
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0171 0.1362
Leishmania major tyrosine specific protein phosphatase, putative 0.0019 0.0031 0.0145
Echinococcus granulosus mitogen activated protein kinase 3 0.0056 0.0466 0.0466
Leishmania major cytochrome p450-like protein 0.0019 0.004 0.0212
Loa Loa (eye worm) RNA binding protein 0.0072 0.0656 0.0755
Echinococcus multilocularis acetylcholinesterase 0.0268 0.2978 0.2978
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.002 0.0045 0.0045
Schistosoma mansoni hypothetical protein 0.0319 0.3572 0.3572
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0019 0.0031 0.0015
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0162 0.0988
Echinococcus multilocularis neuropeptide receptor 0.0092 0.09 0.09
Brugia malayi hypothetical protein 0.0019 0.0031 0.0015
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0092 0.09 0.09
Trypanosoma cruzi lanosterol synthase, putative 0.0145 0.1527 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0206 0.2237 0.2608
Loa Loa (eye worm) hypothetical protein 0.003 0.0162 0.0175
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0007
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0019 0.0031 0.0022
Echinococcus multilocularis mitogen activated protein kinase 3 0.0056 0.0466 0.0466
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0092 0.09 0.09
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0097 0.0959 0.1104
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0046 0.0352 0.0352
Onchocerca volvulus 0.0092 0.09 0.3249
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0092 0.09 0.09
Onchocerca volvulus 0.0061 0.0525 0.1868
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0656 0.0656
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0025 0.0107 0.0104
Brugia malayi Carboxylesterase family protein 0.0268 0.2978 0.3473
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.002 0.0045 0.0104
Onchocerca volvulus 0.0029 0.0157 0.0512
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0046 0.0352 0.0352
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0025 0.0107 0.0107
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0019 0.0031 0.0122
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0078 0.0731 0.4747
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0038
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0019 0.0031 0.0015
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0019 0.0031 0.0122
Loa Loa (eye worm) hypothetical protein 0.0045 0.0345 0.039
Onchocerca volvulus 0.0092 0.09 0.3249
Schistosoma mansoni ran 0.0022 0.0069 0.0069
Onchocerca volvulus 0.0046 0.0352 0.1229
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0019 0.0031 0.0031
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0019 0.0031 0.0015
Loa Loa (eye worm) protein tyrosine phosphatase 0.0019 0.0031 0.0022
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0068 0.0617 0.0703
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0025 0.0107 0.0111
Leishmania major importin beta-1 subunit, putative 0.0024 0.0095 0.0648
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0019 0.0031 0.0031
Schistosoma mansoni cpg binding protein 0.0064 0.0566 0.0566
Onchocerca volvulus 0.0019 0.0031 0.0048
Echinococcus multilocularis g protein coupled receptor 0.0092 0.09 0.09
Brugia malayi MH2 domain containing protein 0.0135 0.1402 0.1624
Onchocerca volvulus 0.0019 0.0031 0.0048
Onchocerca volvulus 0.0092 0.09 0.3249
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0018 0.0018 0.0007
Onchocerca volvulus 0.0019 0.0031 0.0048
Echinococcus granulosus serotonin transporter 0.0148 0.1561 0.1561
Schistosoma mansoni importin beta-1 0.003 0.0162 0.0162
Brugia malayi orphan nuclear receptor NR2E1 0.0046 0.0352 0.0391
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0019 0.0031 0.0031
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.002 0.0045 0.0104
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0107 0.0107
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0097 0.0959 0.0959
Schistosoma mansoni sodium/chloride dependent transporter 0.0026 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0097 0.0959 0.111
Schistosoma mansoni nuclear receptor 0.0046 0.0352 0.0352
Echinococcus multilocularis g protein coupled receptor 0.0092 0.09 0.09
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0045 0.0345 0.4446
Echinococcus granulosus tm gpcr rhodopsin 0.0092 0.09 0.09
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0069 0.0373
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0018 0.0018
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0107 0.0107
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0097 0.0959 0.1104
Plasmodium vivax aspartyl protease, putative 0.0018 0.0018 0.0194
Onchocerca volvulus 0.0029 0.0157 0.0512
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Onchocerca volvulus 0.0045 0.0345 0.1205
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0024 0.0077
Loa Loa (eye worm) transcription factor SMAD2 0.0135 0.1402 0.163
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0019 0.0031 0.0022
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0092 0.09 0.09
Schistosoma mansoni hypothetical protein 0.0042 0.0301 0.0301
Brugia malayi hypothetical protein 0.0045 0.0345 0.0384
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.004 0.0032
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0397 0.4503 0.4503
Echinococcus multilocularis hypothetical protein 0.0019 0.0031 0.0031
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0171 0.0171
Onchocerca volvulus 0.0019 0.0031 0.0048
Schistosoma mansoni microtubule-associated protein tau 0.0703 0.8113 0.8113
Loa Loa (eye worm) hypothetical protein 0.0046 0.0352 0.0398
Echinococcus multilocularis somatostatin receptor 0.0092 0.09 0.09
Plasmodium falciparum plasmepsin VIII, putative 0.0018 0.0018 0.0194
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0056 0.0466 0.2994
Plasmodium vivax geranylgeranyltransferase, putative 0.002 0.0045 0.1118
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.09 0.09
Echinococcus multilocularis neuropeptide Y receptor 0.0092 0.09 0.09
Loa Loa (eye worm) hypothetical protein 0.0148 0.1555 0.1809
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Brugia malayi nuclear hormone receptor 0.0046 0.0352 0.0391
Brugia malayi ORL1-like opioid receptor 0.0092 0.09 0.1035
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0097 0.0959 0.0959
Schistosoma mansoni hypothetical protein 0.0092 0.09 0.09
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0466 0.2994
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0107 0.0107
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0092 0.09 0.09
Onchocerca volvulus 0.0019 0.0031 0.0048
Plasmodium vivax aspartyl protease, putative 0.0018 0.0018 0.0194
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0097 0.0959 0.1104
Brugia malayi nuclear receptor NHR-88 0.0046 0.0352 0.0391
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Trichomonas vaginalis set domain proteins, putative 0.0234 0.257 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0092 0.09 0.09
Echinococcus multilocularis neuropeptide Y receptor 0.0092 0.09 0.09
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0025 0.0107 0.0107
Onchocerca volvulus 0.0092 0.09 0.3249
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Plasmodium vivax farnesyltransferase beta subunit, putative 0.002 0.0045 0.1118
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0051 0.0417 0.0417
Schistosoma mansoni rab6-interacting 0.0042 0.0301 0.0301
Brugia malayi Serotonin receptor 0.0092 0.09 0.1035
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0019 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0045 0.0345 0.039
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Brugia malayi neuropeptide F receptor 0.0092 0.09 0.1035
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0045 0.0345 0.0345
Brugia malayi nuclear hormone receptor family member nhr-6 0.0046 0.0352 0.0391
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0092 0.09 0.1035
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0019 0.0031 0.0031
Schistosoma mansoni rab6-interacting 0.0042 0.0301 0.0301
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.002 0.0045 0.0045
Plasmodium falciparum amino acid transporter, putative 0.0025 0.0107 0.3274
Brugia malayi intermediate filament protein 0.0029 0.0157 0.0163
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0024 1
Giardia lamblia Kinase, CMGC MAPK 0.0056 0.0466 0.6246
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0051 0.0417 0.0417
Onchocerca volvulus 0.0092 0.09 0.3249
Echinococcus granulosus Nuclear hormone receptor HR96 0.0046 0.0352 0.0352
Brugia malayi hypothetical protein 0.0051 0.0417 0.0468
Brugia malayi Carboxylesterase family protein 0.0268 0.2978 0.3473
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0731 0.2796
Loa Loa (eye worm) solute carrier family 6 member 4 0.0148 0.1561 0.1815
Schistosoma mansoni hypothetical protein 0.0732 0.8456 0.8456
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0025 0.0107 0.0107
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0092 0.09 0.09
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0069 0.006
Echinococcus multilocularis G protein coupled receptor 139 0.0092 0.09 0.09
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0095 0.0303
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0148 0.1561 0.1561
Echinococcus granulosus sodium and chloride dependent glycine 0.0025 0.0107 0.0107
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0019 0.0031 0.0031
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0019 0.0031 0.0031
Echinococcus granulosus neuroligin 0.0045 0.0345 0.0345
Schistosoma mansoni nuclear receptor nhr-48 0.0046 0.0352 0.0352
Plasmodium falciparum transporter, putative 0.0025 0.0107 0.3274
Echinococcus multilocularis g protein coupled receptor 0.0092 0.09 0.09
Echinococcus multilocularis RUN 0.0042 0.0301 0.0301
Schistosoma mansoni cathepsin D (A01 family) 0.0018 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0268 0.2978 0.3478
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0092 0.09 0.3249
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0107 0.0107
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0056 0.0466 0.3544
Loa Loa (eye worm) hypothetical protein 0.0025 0.0107 0.0111
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0092 0.09 0.1041
Schistosoma mansoni lipoxygenase 0.0042 0.0301 0.0301
Echinococcus multilocularis BC026374 protein (S09 family) 0.0045 0.0345 0.0345
Brugia malayi nuclear receptor NHR-67 0.0046 0.0352 0.0391
Schistosoma mansoni RAR-like nuclear receptor 0.0097 0.0959 0.0959
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.0417 0.0468
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0045 0.0213
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0092 0.09 0.09
Echinococcus multilocularis g-protein coupled receptor 0.0092 0.09 0.09
Loa Loa (eye worm) hypothetical protein 0.0247 0.2732 0.3189
Brugia malayi hypothetical protein 0.0019 0.0031 0.0015
Echinococcus granulosus orexin receptor type 2 0.0092 0.09 0.09
Brugia malayi hypothetical protein 0.0092 0.09 0.1035
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0466 0.1755
Brugia malayi GnHR receptor homolog 0.0092 0.09 0.1035
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0466 0.0466
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0025 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0095 0.0548
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0162 0.1284
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0018 0.0018
Schistosoma mansoni ran 0.0022 0.0069 0.0069
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.09 0.09
Loa Loa (eye worm) TAR-binding protein 0.0072 0.0656 0.0755
Schistosoma mansoni hypothetical protein 0.0017 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Brugia malayi hypothetical protein 0.0042 0.0301 0.0332
Brugia malayi CXXC zinc finger family protein 0.0061 0.0525 0.0595
Onchocerca volvulus 0.0092 0.09 0.3249
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0018 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Loa Loa (eye worm) carboxylesterase 0.0045 0.0345 0.039
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0019 0.0031 0.0031
Plasmodium falciparum protein farnesyltransferase subunit beta 0.002 0.0045 0.1118
Schistosoma mansoni biogenic amine (5HT) receptor 0.0092 0.09 0.09
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0025 0.0107 0.0107
Onchocerca volvulus 0.0092 0.09 0.3249
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.002 0.0045 0.0277
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0078 0.0731 0.0731
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0092 0.09 0.09
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Loa Loa (eye worm) hypothetical protein 0.0045 0.0345 0.039
Schistosoma mansoni amine GPCR 0.0092 0.09 0.09
Schistosoma mansoni hypothetical protein 0.0068 0.0617 0.0617
Schistosoma mansoni cpg binding protein 0.0061 0.0525 0.0525
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0097 0.0959 0.111
Echinococcus multilocularis neuropeptides capa receptor 0.0092 0.09 0.09
Brugia malayi Melatonin receptor type 1A 0.0092 0.09 0.1035
Loa Loa (eye worm) MH2 domain-containing protein 0.0135 0.1402 0.163
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Echinococcus granulosus G protein coupled receptor 139 0.0092 0.09 0.09
Schistosoma mansoni BC026374 protein (S09 family) 0.0045 0.0345 0.0345
Schistosoma mansoni intermediate filament proteins 0.0029 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0097 0.0959 0.111
Loa Loa (eye worm) acetylcholinesterase 1 0.0268 0.2978 0.3478
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.002 0.0045 0.0213
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.004 0.0032
Echinococcus multilocularis fmrfamide receptor 0.0092 0.09 0.09
Plasmodium falciparum plasmepsin III 0.0018 0.0018 0.0194
Echinococcus granulosus 7tm_1 domain containing protein 0.0092 0.09 0.09
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0097 0.0959 0.0959
Echinococcus multilocularis acetylcholinesterase 0.0268 0.2978 0.2978
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0097 0.0959 0.111
Echinococcus granulosus alpha 1A adrenergic receptor 0.0092 0.09 0.09
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0025 0.0107 0.0107
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0019 0.0031 0.0031
Trypanosoma brucei lanosterol synthase 0.0145 0.1527 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0068 0.0617 0.0617
Brugia malayi hypothetical protein 0.0019 0.0031 0.0015
Leishmania major GTP-binding protein, putative 0.0022 0.0069 0.0442
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0046 0.0352 0.0391
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0019 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0369 0.0369
Echinococcus multilocularis cpg binding protein 0.0064 0.0566 0.0566
Giardia lamblia Prenyltransferase 0.002 0.0045 0.029
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0319 0.3572 0.4174
Schistosoma mansoni cpg binding protein 0.0064 0.0566 0.0566
Schistosoma mansoni hypothetical protein 0.0051 0.0409 0.0409
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0019 0.0031 0.0015
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.002 0.0045 0.0104
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0046 0.0352 0.1229
Loa Loa (eye worm) hypothetical protein 0.0097 0.0959 0.111
Echinococcus granulosus sodium and chloride dependent glycine 0.0025 0.0107 0.0107
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0095 0.0303
Echinococcus multilocularis snurportin 1 0.0319 0.3572 0.3572
Echinococcus multilocularis musashi 0.0029 0.0157 0.0157
Onchocerca volvulus 0.0019 0.0031 0.0048
Loa Loa (eye worm) hypothetical protein 0.0042 0.0301 0.0338
Onchocerca volvulus 0.0092 0.09 0.3249
Schistosoma mansoni ap endonuclease 0.0018 0.0024 0.0024
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.002 0.0045 0.0213
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0097 0.0959 0.3466
Echinococcus multilocularis nuclear receptor nhr 48 0.0046 0.0352 0.0352
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0107 0.081
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0019 0.0031 0.0031
Plasmodium falciparum plasmepsin II 0.0018 0.0018 0.0194
Schistosoma mansoni monoxygenase 0.0017 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Echinococcus granulosus intermediate filament protein 0.0029 0.0157 0.0157
Onchocerca volvulus 0.0234 0.257 0.9403
Schistosoma mansoni protein tyrosine phosphatase 0.0019 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Echinococcus multilocularis GPCR, family 2 0.0068 0.0617 0.0617
Echinococcus granulosus lamin dm0 0.0029 0.0157 0.0157
Echinococcus granulosus microtubule associated protein 2 0.0703 0.8113 0.8113
Echinococcus granulosus biogenic amine 5HT receptor 0.0092 0.09 0.09
Brugia malayi hypothetical protein 0.0092 0.09 0.1035
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0092 0.09 0.09
Schistosoma mansoni biogenic amine (5HT) receptor 0.0092 0.09 0.09
Echinococcus multilocularis neuropeptide receptor 0.0092 0.09 0.09
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0369 0.0369
Echinococcus granulosus acetylcholinesterase 0.0268 0.2978 0.2978
Trypanosoma cruzi protein farnesyltransferase, putative 0.002 0.0045 0.0213
Onchocerca volvulus Protein ultraspiracle homolog 0.0097 0.0959 0.3466
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.002 0.0045 0.0104
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Brugia malayi hypothetical protein 0.0092 0.09 0.1035
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0092 0.09 0.09
Brugia malayi Nuclear hormone receptor-like 1 0.0097 0.0959 0.1104
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.002 0.0045 0.029
Brugia malayi conserved hypotetical protein 0.0046 0.0352 0.0391
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0092 0.09 0.09
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0019 0.0031 0.0031
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0157 0.0163
Echinococcus multilocularis G-protein coupled receptor, putative 0.0092 0.09 0.09
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0024 0.0157
Schistosoma mansoni nuclear hormone receptor 0.0097 0.0959 0.0959
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0024 0.0406
Schistosoma mansoni amine GPCR 0.0092 0.09 0.09
Echinococcus granulosus g protein coupled receptor 0.0092 0.09 0.09
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0466 0.1755
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.004 0.0179
Echinococcus granulosus thyroid hormone receptor alpha 0.0046 0.0352 0.0352
Brugia malayi TAR-binding protein 0.0072 0.0656 0.0749
Loa Loa (eye worm) hypothetical protein 0.0148 0.1561 0.1815
Onchocerca volvulus 0.0019 0.0031 0.0048
Brugia malayi RNA binding protein 0.0072 0.0656 0.0749
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0107 0.0104
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0019 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Echinococcus granulosus serotonin receptor 0.0092 0.09 0.09
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0045 0.0345 0.0345
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.09 0.09
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.09 0.09
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.002 0.0045 0.029
Brugia malayi Carboxylesterase family protein 0.0045 0.0345 0.0384
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Trypanosoma brucei cytochrome P450, putative 0.0019 0.004 0.0179
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0171 0.0171
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0019 0.0031 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.09 0.09
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0092 0.09 0.09
Brugia malayi Pre-SET motif family protein 0.0031 0.0171 0.018
Echinococcus multilocularis carboxylesterase 5A 0.0268 0.2978 0.2978
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0019 0.0031 0.0015
Onchocerca volvulus 0.0045 0.0345 0.1205
Echinococcus granulosus tm gpcr rhodopsin 0.0092 0.09 0.09
Brugia malayi Dopamine receptor protein 2 0.0092 0.09 0.1035
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0466 0.2994
Treponema pallidum sodium- and chloride- dependent transporter 0.0148 0.1561 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0046 0.0352 0.0352
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.09 0.09
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0018 0.0018 0.0048
Schistosoma mansoni retinoic acid receptor RXR 0.0097 0.0959 0.0959
Loa Loa (eye worm) hypothetical protein 0.0025 0.0107 0.0111
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0107 0.0107
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0069 0.0634
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Loa Loa (eye worm) DR-78 0.0046 0.0352 0.0398
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0092 0.09 0.1041
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0045 0.0345 0.0345
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0019 0.0031 0.0031
Loa Loa (eye worm) serotonin transporter b 0.0148 0.1561 0.1815
Onchocerca volvulus 0.0019 0.0031 0.0048
Loa Loa (eye worm) hypothetical protein 0.0097 0.0959 0.111
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0019 0.0031 0.0096
Brugia malayi nuclear hormone receptor family member odr-7 0.0046 0.0352 0.0391
Schistosoma mansoni neuropeptide f receptor 76f 0.0092 0.09 0.09
Brugia malayi G protein-coupled receptor F59B2.13 0.0092 0.09 0.1035
Schistosoma mansoni loxhd1 0.0042 0.0301 0.0301
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0097 0.0959 0.0959
Echinococcus granulosus neuropeptides capa receptor 0.0092 0.09 0.09
Echinococcus multilocularis neuropeptide FF receptor 2 0.0092 0.09 0.09
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.09 0.09
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Echinococcus granulosus protein tyrosine phosphatase n9 0.0019 0.0031 0.0031
Brugia malayi Cytochrome P450 family protein 0.0029 0.0155 0.0161
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.09 0.09
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0019 0.0031 0.0031
Onchocerca volvulus 0.0019 0.0031 0.0048
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0007
Loa Loa (eye worm) hypothetical protein 0.0025 0.0107 0.0111
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0097 0.0959 0.0959
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.004 0.0179
Loa Loa (eye worm) steroid hormone receptor 0.0097 0.0959 0.111
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0019 0.0031 0.0015
Brugia malayi latrophilin 2 splice variant baaae 0.0148 0.1555 0.1803
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0019 0.0031 0.0022
Echinococcus granulosus FTZ F1 alpha 0.0097 0.0959 0.0959
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0019 0.0031 0.0015
Loa Loa (eye worm) hypothetical protein 0.0046 0.0352 0.0398
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0025 0.0107 0.0111
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0025 0.0107 0.0107
Brugia malayi hypothetical protein 0.0092 0.09 0.1035
Onchocerca volvulus 0.0045 0.0345 0.1205
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Trichomonas vaginalis spcc417.12 protein, putative 0.0045 0.0345 0.1281
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0045 0.0345 0.1281
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.09 0.09
Onchocerca volvulus 0.0019 0.0031 0.0048
Echinococcus multilocularis rhodopsin orphan GPCR 0.0092 0.09 0.09
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0097 0.0959 0.0959
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0301 0.0301
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0171 0.0171
Schistosoma mansoni memapsin-2 (A01 family) 0.044 0.5 0.5
Trypanosoma brucei protein kinase, putative 0.0056 0.0466 0.2994
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0092 0.09 0.09
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0148 0.1561 0.181
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0301 0.0301
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0024 0.0024
Echinococcus multilocularis Polycystic kidney disease protein 0.0042 0.0301 0.0301
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.09 0.09
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0092 0.09 0.09
Echinococcus multilocularis para nitrobenzyl esterase 0.0045 0.0345 0.0345
Onchocerca volvulus 0.0092 0.09 0.3249
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0019 0.0031 0.0122
Echinococcus granulosus Nuclear hormone receptor HR96 0.0046 0.0352 0.0352
Loa Loa (eye worm) hypothetical protein 0.0046 0.0352 0.0398
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.09 0.09
Onchocerca volvulus 0.0042 0.0301 0.1042
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0019 0.0031 0.0031
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0019 0.0031 0.0031
Onchocerca volvulus 0.0046 0.0352 0.1229
Onchocerca volvulus 0.0019 0.0031 0.0048
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0056 0.0466 0.3544
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0097 0.0959 0.0959
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0019 0.0031 0.0031
Echinococcus multilocularis ubiquinone biosynthesis monooxygenase COQ6 0.0017 0.0012 0.0012
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0107 0.081
Echinococcus multilocularis serotonin receptor 0.0092 0.09 0.09
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0107 0.3274
Echinococcus granulosus para nitrobenzyl esterase 0.0045 0.0345 0.0345
Echinococcus granulosus neuropeptide Y receptor 0.0092 0.09 0.09
Brugia malayi Nuclear hormone receptor E75 0.0046 0.0352 0.0391
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0301 0.0301
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0092 0.09 0.09
Loa Loa (eye worm) G-protein coupled receptor 0.0092 0.09 0.1041
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0024 0.0014
Loa Loa (eye worm) TYRA-2 protein 0.0092 0.09 0.1041
Onchocerca volvulus 0.0019 0.0031 0.0048
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0078 0.0731 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0097 0.0959 0.1104
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0092 0.09 0.09
Echinococcus granulosus Polycystic kidney disease protein 0.0042 0.0301 0.0301
Schistosoma mansoni amine GPCR 0.0092 0.09 0.09
Echinococcus granulosus protein farnesyltransferase subunit beta 0.002 0.0045 0.0045
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0019 0.0031 0.0022
Brugia malayi nuclear hormone receptor 0.0097 0.0959 0.1104
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0069 0.0069
Brugia malayi Protein-tyrosine phosphatase 0.0019 0.0031 0.0015
Echinococcus granulosus biogenic amine 5HT receptor 0.0092 0.09 0.09
Trypanosoma cruzi lanosterol synthase, putative 0.0145 0.1527 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0216 0.2363 0.2751
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.002 0.0045 0.0045
Echinococcus granulosus neuropeptide FF receptor 2 0.0092 0.09 0.09
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0092 0.09 0.1035
Echinococcus granulosus RUN 0.0042 0.0301 0.0301
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0019 0.0031 0.0031
Onchocerca volvulus 0.0019 0.0031 0.0048
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0369 0.0369
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0116 0.1185 0.1185
Echinococcus multilocularis lamin dm0 0.0029 0.0157 0.0157
Echinococcus multilocularis neuropeptide receptor A26 0.0092 0.09 0.09
Brugia malayi sulfakinin receptor protein 0.0092 0.09 0.1035
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0019 0.0031 0.0022
Brugia malayi Steroid receptor seven-up type 2 0.0097 0.0959 0.1104
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0656 0.0656
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0092 0.09 0.09
Echinococcus multilocularis microtubule associated protein 2 0.0703 0.8113 0.8113
Onchocerca volvulus 0.0025 0.0107 0.0327
Schistosoma mansoni hypothetical protein 0.0148 0.1555 0.1555
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0092 0.09 0.09
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.002 0.0045 0.0038
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0739 0.8541 1
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0128 0.1324 0.1324
Echinococcus multilocularis mitogen activated protein kinase 0.0056 0.0466 0.0466
Brugia malayi follicle stimulating hormone receptor 0.0092 0.09 0.1035
Echinococcus multilocularis geminin 0.0732 0.8456 0.8456
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0068 0.0617 0.0617
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0019 0.0031 0.0022
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.002 0.0045 0.0045
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0019 0.0031 0.0015
Toxoplasma gondii histone lysine methyltransferase SET1 0.0116 0.1178 1
Onchocerca volvulus 0.0025 0.0107 0.0327
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0092 0.09 0.1035
Brugia malayi Dopamine receptor protein 1 0.0092 0.09 0.1035
Loa Loa (eye worm) hypothetical protein 0.0051 0.0417 0.0474
Brugia malayi Tachykinin-like peptides receptor 99D 0.0092 0.09 0.1035
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0051 0.0417 0.0417
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0019 0.0031 0.0031
Mycobacterium leprae possibleputative FAD-linked oxidoreductase 0.0017 0.0012 0.5
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Brugia malayi putative neuropeptide receptor NPR1 0.0092 0.09 0.1035
Echinococcus multilocularis serotonin transporter 0.0148 0.1561 0.1561
Schistosoma mansoni sodium-dependent amino acid transporter 0.0025 0.0107 0.0107
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0097 0.0959 0.111
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0019 0.0031 0.0031
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0078 0.0731 1
Schistosoma mansoni opsin-like receptor 0.0092 0.09 0.09
Echinococcus multilocularis neuroligin 0.0045 0.0345 0.0345
Echinococcus multilocularis importin subunit beta 1 0.003 0.0162 0.0162
Echinococcus multilocularis ecdysone induced protein 78C 0.0097 0.0959 0.0959
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0128 0.1324 0.1324
Onchocerca volvulus 0.0092 0.09 0.3249
Onchocerca volvulus 0.0019 0.0031 0.0048
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0024 0.0092
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0068 0.0617 0.0617
Schistosoma mansoni lamin 0.0029 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0046 0.0352 0.0398
Brugia malayi MAP kinase sur-1 0.0056 0.0466 0.0526
Brugia malayi ecdysteroid receptor 0.0247 0.2732 0.3184
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0018 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0268 0.2978 0.3478
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.0417 0.0468
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0466 0.1755
Brugia malayi Serotonin receptor 0.0092 0.09 0.1035
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0078 0.0731 0.4747
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0092 0.09 0.09
Schistosoma mansoni hypothetical protein 0.0863 1 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0352 0.0398
Echinococcus granulosus neuropeptide receptor 0.0092 0.09 0.09
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0019 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Trypanosoma cruzi protein farnesyltransferase, putative 0.002 0.0045 0.0213
Plasmodium vivax plasmepsin V, putative 0.0018 0.0018 0.0194
Echinococcus granulosus rhodopsin orphan GPCR 0.0092 0.09 0.09
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0045 0.0345 0.0345
Loa Loa (eye worm) hypothetical protein 0.0025 0.0107 0.0111
Loa Loa (eye worm) neuropeptide F receptor 0.0092 0.09 0.1041
Loa Loa (eye worm) hypothetical protein 0.0025 0.0107 0.0111
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Echinococcus multilocularis FTZ F1 alpha 0.0097 0.0959 0.0959
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0019 0.0031 0.0031
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0019 0.0031 0.0031
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0092 0.09 0.09
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0019 0.0031 0.0015
Onchocerca volvulus 0.0042 0.0301 0.1042
Schistosoma mansoni coup transcription factor 0.0097 0.0959 0.0959
Loa Loa (eye worm) hypothetical protein 0.0097 0.0959 0.111
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0171 0.0171
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Echinococcus multilocularis serotonin receptor 0.0092 0.09 0.09
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0019 0.0031 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0097 0.0959 0.1104
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0019 0.0031 0.0015
Schistosoma mansoni gliotactin 0.0045 0.0345 0.0345
Echinococcus multilocularis dnaJ subfamily B 0.0863 1 1
Mycobacterium tuberculosis Carboxylesterase LipT 0.0045 0.0345 0.4446
Schistosoma mansoni nuclear hormone receptor 0.0046 0.0352 0.0352
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0025 0.0107 0.0107
Brugia malayi RNA recognition motif domain containing protein 0.0072 0.0656 0.0749
Onchocerca volvulus 0.0019 0.0031 0.0048
Schistosoma mansoni mixed-lineage leukemia protein mll 0.013 0.134 0.134
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0078 0.0731 0.0731
Schistosoma mansoni nuclear receptor 0.0046 0.0352 0.0352
Onchocerca volvulus 0.0019 0.0031 0.0048
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0107 0.081
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0097 0.0959 0.111
Trypanosoma brucei protein tyrosine phosphatase 1 0.0019 0.0031 0.0122
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.09 0.09
Brugia malayi RNA, U transporter 1 0.0085 0.0812 0.0931
Schistosoma mansoni opsin-like receptor 0.0092 0.09 0.09
Loa Loa (eye worm) G-protein coupled receptor 0.0092 0.09 0.1041
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0046 0.0352 0.0398
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0045 0.0213
Brugia malayi tailless protein 0.0046 0.0352 0.0391
Plasmodium falciparum plasmepsin IV 0.0018 0.0018 0.0194
Echinococcus multilocularis sodium and chloride dependent glycine 0.0025 0.0107 0.0107
Echinococcus multilocularis neuropeptides capa receptor 0.0092 0.09 0.09
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0157 0.0169
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Schistosoma mansoni neuropeptide receptor 0.0092 0.09 0.09
Plasmodium falciparum importin beta, putative 0.003 0.0162 0.5188
Schistosoma mansoni neuropeptide F-like receptor 0.0092 0.09 0.09
Schistosoma mansoni protein farnesyltransferase subunit beta 0.002 0.0045 0.0045
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0078 0.0731 0.0837
Loa Loa (eye worm) hypothetical protein 0.0046 0.0352 0.0398
Echinococcus granulosus geminin 0.0732 0.8456 0.8456
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0045 0.0345 0.4446
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0019 0.0031 0.0015
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.002 0.0045 0.0104
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0041 0.0027
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0019 0.0031 0.0022
Brugia malayi G protein-coupled receptor 0.0092 0.09 0.1035
Schistosoma mansoni hypothetical protein 0.0068 0.0617 0.0617
Brugia malayi ecdysone receptor 0.0046 0.0352 0.0391
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0116 0.1185 0.1185
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0097 0.0959 0.111
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0019 0.0031 0.0022
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0069 0.0373
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0097 0.0959 0.1104
Schistosoma mansoni tar DNA-binding protein 0.0072 0.0656 0.0656
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Brugia malayi Carboxylesterase family protein 0.0045 0.0345 0.0384
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0097 0.0959 0.0959
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0092 0.09 0.09
Schistosoma mansoni polycystin 1-related 0.0042 0.0301 0.0301
Schistosoma mansoni neuropeptide receptor 0.0092 0.09 0.09
Giardia lamblia Protein tyrosine phosphatase 0.0019 0.0031 0.0096
Loa Loa (eye worm) hypothetical protein 0.0019 0.0031 0.0022
Loa Loa (eye worm) carboxylesterase 0.0045 0.0345 0.039
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0107 0.0107
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0046 0.0352 0.0352
Echinococcus granulosus somatostatin receptor 0.0092 0.09 0.09
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0069 0.0485
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0092 0.09 0.1041
Echinococcus multilocularis dro:myosuppressin receptor 0.0092 0.09 0.09
Plasmodium vivax SET domain protein, putative 0.0031 0.0171 0.5503
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0019 0.0031 0.0015
Echinococcus granulosus tm gpcr rhodopsin 0.0092 0.09 0.09
Brugia malayi Importin beta-1 subunit 0.003 0.0162 0.0169
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0081 0.076 1
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0019 0.0031 0.0031
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0019 0.0031 0.0015
Echinococcus granulosus sex peptide receptor 0.0092 0.09 0.09
Echinococcus multilocularis ubiquitin specific protease 41 0.0078 0.0731 0.0731
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0019 0.0031 0.0022
Echinococcus granulosus protein MICAL 3 0.0017 0.0012 0.0012
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0097 0.0959 0.0959
Echinococcus granulosus lamin 0.0029 0.0157 0.0157
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0019 0.0031 0.0015
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0369 0.0418
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0024 0.0024
Brugia malayi RE15519p 0.0092 0.09 0.1035
Echinococcus multilocularis thyroid hormone receptor alpha 0.0226 0.2474 0.2474
Onchocerca volvulus Neuropeptide F receptor homolog 0.0092 0.09 0.3249
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0024 0.0077
Entamoeba histolytica hypothetical protein 0.0024 0.0095 0.1007
Brugia malayi hypothetical protein 0.0092 0.09 0.1035
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0171 0.0171
Onchocerca volvulus 0.0025 0.0107 0.0327
Loa Loa (eye worm) CYP4Cod1 0.0019 0.004 0.0032
Plasmodium falciparum plasmepsin I 0.0018 0.0018 0.0194
Brugia malayi G-protein coupled receptor 0.0092 0.09 0.1035
Echinococcus granulosus GPCR family 2 0.0068 0.0617 0.0617
Schistosoma mansoni hypothetical protein 0.0092 0.09 0.09
Echinococcus granulosus snurportin 1 0.0319 0.3572 0.3572
Schistosoma mansoni pcd6 interacting protein-related 0.0019 0.0031 0.0031
Echinococcus multilocularis tar DNA binding protein 0.0072 0.0656 0.0656
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0019 0.0031 0.0031
Loa Loa (eye worm) nuclear hormone receptor 0.0046 0.0352 0.0398
Loa Loa (eye worm) hypothetical protein 0.0029 0.0151 0.0162
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0019 0.0031 0.0015
Schistosoma mansoni neuroligin 3 (S09 family) 0.0045 0.0345 0.0345
Schistosoma mansoni neuropeptide receptor 0.0092 0.09 0.09
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0092 0.09 0.1041
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0019 0.004 0.0817
Schistosoma mansoni hypothetical protein 0.0128 0.1324 0.1324
Brugia malayi hypothetical protein 0.0046 0.0352 0.0391
Echinococcus multilocularis protein MICAL 3 0.0017 0.0012 0.0012
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0092 0.09 0.09
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0369 0.0411
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0019 0.0031 0.0031
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0097 0.0959 0.111
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0046 0.0352 0.0352
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.002 0.0045 0.1118
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0092 0.09 0.1041
Onchocerca volvulus 0.0019 0.0031 0.0048
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0044 0.0044
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0466 0.1755
Schistosoma mansoni thyroid hormone receptor 0.0226 0.2474 0.2474
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0092 0.09 0.09

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 0.094 mM Inhibitory binding constant against glycogen phosphorylase B ChEMBL. 15163189

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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