Detailed information for compound 1740104

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 543.005 | Formula: C29H31ClO8
  • H donors: 0 H acceptors: 5 LogP: 4.51 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C[C@@H]1C(C)(C)CC[C@@H]([C@@]21COC(=O)[C@]13[C@H]2CC[C@@H]([C@H]1OC(=O)c1ccc(cc1)Cl)C(=C)C3=O)OC(=O)C
  • InChi: 1S/C29H31ClO8/c1-15-19-9-10-20-28(21(13-31)27(3,4)12-11-22(28)37-16(2)32)14-36-26(35)29(20,23(15)33)24(19)38-25(34)17-5-7-18(30)8-6-17/h5-8,13,19-22,24H,1,9-12,14H2,2-4H3/t19-,20+,21-,22+,24-,28+,29+/m1/s1
  • InChiKey: NYHOAKNYZLIYJS-JDOWWISBSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni alpha-1 adrenergic receptor 0.0295 0.1077 0.1804
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0006 0.0006
Onchocerca volvulus 0.0045 0.0121 0.062
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.006 0.018 0.018
Onchocerca volvulus 0.0295 0.1077 0.5782
Schistosoma mansoni smad1 5 8 and 0.0041 0.0105 0.0177
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.006 0.018 0.0269
Mycobacterium tuberculosis Conserved protein 0.0071 0.0221 0.0323
Entamoeba histolytica hypothetical protein 0.0039 0.0098 0.0362
Brugia malayi G protein-coupled receptor 0.0295 0.1077 0.1077
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.006 0.018 0.018
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0295 0.1077 0.1613
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.0171 0.0287
Loa Loa (eye worm) inositol-1 0.0039 0.0097 0.0091
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.003 0.0048
Brugia malayi G-protein coupled receptor 0.0295 0.1077 0.1077
Echinococcus granulosus rhodopsin orphan GPCR 0.0295 0.1077 0.1804
Schistosoma mansoni smad1 5 8 and 0.0041 0.0105 0.0177
Echinococcus granulosus dro:myosuppressin receptor 0.0295 0.1077 0.1804
Plasmodium vivax flap endonuclease 1, putative 0.0055 0.0159 0.463
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.004 0.0101 0.0095
Loa Loa (eye worm) G-protein coupled receptor 0.0295 0.1077 0.1071
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0054 0.1584
Echinococcus granulosus Smad4 0.0041 0.0105 0.0177
Loa Loa (eye worm) hypoxia-induced factor 1 0.0153 0.0532 0.0526
Echinococcus granulosus rhodopsin orphan GPCR 0.0295 0.1077 0.1804
Loa Loa (eye worm) hypothetical protein 0.0033 0.0073 0.0067
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0 0.0001
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0018 0.0486
Loa Loa (eye worm) hypothetical protein 0.002 0.0026 0.0019
Schistosoma mansoni hypothetical protein 0.0037 0.0091 0.0153
Loa Loa (eye worm) hypothetical protein 0.0055 0.0161 0.0154
Echinococcus multilocularis jumonji domain containing 1A 0.0033 0.0075 0.0113
Loa Loa (eye worm) hypothetical protein 0.0028 0.0056 0.0049
Brugia malayi Cell death protein 3 precursor 0.0098 0.0323 0.0323
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.006 0.018 0.0173
Onchocerca volvulus 0.0295 0.1077 0.5782
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0295 0.1077 0.1804
Echinococcus granulosus potassium channel subfamily K 8 0.0045 0.0121 0.0203
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0295 0.1077 0.1071
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0312 0.1141 0.1135
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0052 0.0148 0.0764
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0006 0.0162
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0015 0.0015
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0579 0.2649
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0197 0.0703 0.1053
Echinococcus multilocularis dro:myosuppressin receptor 0.0295 0.1077 0.1613
Loa Loa (eye worm) hypothetical protein 0.115 0.434 0.4337
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0051 0.0145 0.0707
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0028 0.0056 0.0083
Echinococcus granulosus snurportin 1 0.0312 0.1141 0.1911
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0045 0.0121 0.0121
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0252 0.6331
Onchocerca volvulus 0.0045 0.0121 0.062
Schistosoma mansoni opsin-like receptor 0.0295 0.1077 0.1804
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0252 0.6331
Echinococcus granulosus 7TM GPCR rhodopsin 0.0295 0.1077 0.1804
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0252 0.1229
Loa Loa (eye worm) ACC-1 protein 0.006 0.018 0.0173
Brugia malayi hypoxia-induced factor 1 0.0153 0.0532 0.0532
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.0221 0.1077
Brugia malayi glucose-6-phosphate dehydrogenase 0.0095 0.031 0.031
Echinococcus granulosus caspase 8 0.0019 0.0023 0.0038
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0013
Echinococcus multilocularis dna polymerase kappa 0.0021 0.003 0.0044
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0098 0.045
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0097 0.0444
Echinococcus granulosus thioredoxin glutathione reductase 0.0039 0.0098 0.0164
Schistosoma mansoni twik family of potassium channels-related 0.0045 0.0121 0.0203
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0019 0.0019
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0019 0.0564
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0031 0.0031
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0056 0.0163 0.0244
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0138 0.023
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0144 0.0241
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0252 0.6866
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0033 0.0075 0.0126
Schistosoma mansoni sex comb on midleg homolog 0.0052 0.0148 0.0248
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.006 0.018 0.0173
Schistosoma mansoni biogenic amine receptor 0.0295 0.1077 0.1804
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0082 0.0264 0.1131
Echinococcus granulosus RUN 0.002 0.0026 0.0043
Onchocerca volvulus Cell death protein 3 homolog 0.0098 0.0323 0.1711
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.047 0.0787
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0023 0.0576
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.003 0.0145
Loa Loa (eye worm) hypothetical protein 0.0088 0.0286 0.028
Schistosoma mansoni hypothetical protein 0.0079 0.025 0.0418
Loa Loa (eye worm) neuropeptide F receptor 0.0295 0.1077 0.1071
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0045 0.0121 0.0121
Echinococcus granulosus nAChR subunit 0.0033 0.0073 0.0123
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.18 0.6825 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0194 0.0325
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0014 0.0023
Plasmodium falciparum thioredoxin reductase 0.0038 0.0096 0.2795
Echinococcus granulosus potassium channel subfamily K 0.0045 0.0121 0.0203
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.003 0.003
Onchocerca volvulus 0.0295 0.1077 0.5782
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0036 0.0088 0.0148
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0028 0.0056 0.0056
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0061 0.1529
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0051 0.0145 0.0212
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.003 0.0136
Leishmania major potassium channel subunit-like protein 0.0045 0.0121 0.0121
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0026 0.0038
Onchocerca volvulus 0.0071 0.0221 0.1157
Loa Loa (eye worm) calcium channel 0.0083 0.0268 0.0262
Onchocerca volvulus Glucosylceramidase homolog 0.0165 0.0579 0.3093
Toxoplasma gondii hypothetical protein 0.0015 0.0006 0.0162
Brugia malayi Cation transporter family protein 0.0129 0.0441 0.0441
Loa Loa (eye worm) glutathione reductase 0.0038 0.0096 0.0089
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0014 0.0021
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0295 0.1077 0.1613
Brugia malayi putative neuropeptide receptor NPR1 0.0295 0.1077 0.1077
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0095 0.031 0.052
Echinococcus granulosus g protein coupled receptor 0.0295 0.1077 0.1804
Leishmania major metacaspase, putative 0.0019 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0978 0.3687 0.6177
Loa Loa (eye worm) doublecortin family protein 0.002 0.0026 0.0019
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.006 0.018 0.0301
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0102 0.034 0.1479
Echinococcus multilocularis caspase 0.0019 0.0023 0.0034
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0045 0.0121 0.0121
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0909 0.416
Loa Loa (eye worm) hypothetical protein 0.0052 0.0149 0.0143
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0103 0.0342 0.8602
Echinococcus multilocularis carboxylesterase 5A 0.0066 0.0202 0.0303
Brugia malayi Smad1 0.0041 0.0105 0.0105
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0028 0.0056 0.0056
Plasmodium vivax importin-beta 2, putative 0.0029 0.0061 0.1778
Toxoplasma gondii transporter, cation channel family protein 0.0031 0.0067 0.1686
Schistosoma mansoni neuropeptide f receptor 76f 0.0295 0.1077 0.1804
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0087 0.0283 0.0415
Onchocerca volvulus 0.0045 0.0121 0.062
Schistosoma mansoni flap endonuclease-1 0.005 0.0138 0.0232
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0015 0.0015
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0033 0.0075 0.0075
Echinococcus multilocularis mothers against decapentaplegic 5 0.0041 0.0105 0.0158
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0084 0.0271 0.124
Brugia malayi jmjC domain containing protein 0.0033 0.0075 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0023 0.0105
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0909 0.416
Mycobacterium leprae putative cytochrome p450 0.0051 0.0145 0.0441
Brugia malayi MH1 domain containing protein 0.0023 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0011
Schistosoma mansoni neurotransmitter gated ion channel 0.0028 0.0056 0.0093
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0194 0.4875
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0051 0.0145 0.0707
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0031 0.0067 0.0067
Brugia malayi Cytochrome P450 family protein 0.0088 0.0284 0.0284
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.003 0.003
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0026 0.0038
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0054 0.1362
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0295 0.1077 0.1071
Loa Loa (eye worm) hypothetical protein 0.002 0.0026 0.0019
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0136 0.047 0.0787
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0295 0.1077 0.1804
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0023 0.0105
Schistosoma mansoni hypothetical protein 0.0839 0.3155 0.5286
Echinococcus multilocularis fmrfamide receptor 0.0295 0.1077 0.1613
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0097 0.0444
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.0487 0.0815
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0016
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.0157 0.0157
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0052 0.0148 0.0452
Echinococcus granulosus SAM and MBT domain containing protein 0.0052 0.0148 0.0248
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0041 0.0041
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0006 0.0011
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0016 0.0454
Plasmodium vivax pyruvate kinase, putative 0.0034 0.0078 0.229
Loa Loa (eye worm) hypothetical protein 0.0101 0.0335 0.0329
Echinococcus multilocularis glycine receptor subunit beta 0.006 0.018 0.0269
Schistosoma mansoni calcium-activated potassium channel 0.0045 0.0121 0.0203
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0054 0.0054
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0295 0.1077 0.1613
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.006 0.018 0.018
Echinococcus multilocularis g protein coupled receptor 0.0295 0.1077 0.1613
Trypanosoma cruzi metacaspase, putative 0.0019 0.0023 0.0023
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0083 0.0268 0.0401
Schistosoma mansoni opsin-like receptor 0.0295 0.1077 0.1804
Schistosoma mansoni cpg binding protein 0.0062 0.0187 0.0314
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.006 0.018 0.018
Echinococcus multilocularis apoptotic protease activating factor 1 0.0079 0.025 0.0374
Plasmodium falciparum transporter, putative 0.0015 0.0006 0.0189
Onchocerca volvulus 0.0033 0.0073 0.0362
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.0171 0.0257
Trypanosoma brucei protein kinase, putative 0.0051 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0011
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0083 0.0268 0.0262
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0079 0.0252 0.0894
Loa Loa (eye worm) hypothetical protein 0.006 0.018 0.0173
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0031 0.0144
Brugia malayi Dopamine receptor 0.0295 0.1077 0.1077
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0015 0.0023
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0221 0.101
Echinococcus multilocularis pyruvate kinase 0.0034 0.0078 0.0117
Schistosoma mansoni sodium-dependent amino acid transporter 0.0015 0.0006 0.0011
Brugia malayi acetyltransferase, GNAT family protein 0.0145 0.0502 0.0502
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0197 0.0703 0.1053
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0078 0.0359
Echinococcus multilocularis rhodopsin orphan GPCR 0.0295 0.1077 0.1613
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0295 0.1077 0.1613
Brugia malayi hypothetical protein 0.0295 0.1077 0.1077
Schistosoma mansoni hypothetical protein 0.1201 0.4538 0.7602
Echinococcus granulosus phd:f box containing protein 0.0033 0.0075 0.0126
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0586 0.2186 1
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0018 0.0019 0.0068
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0058 0.0171 0.0287
Echinococcus granulosus microtubule associated protein 2 0.1394 0.5275 0.8837
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.006 0.018 0.0301
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.006 0.018 0.0301
Schistosoma mansoni rab6-interacting 0.002 0.0026 0.0043
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0019 0.0088
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0014 0.0021
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0144 0.0657
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0019 0.0019
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0026 0.0043
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0579 0.2649
Echinococcus granulosus rhodopsin orphan GPCR 0.0295 0.1077 0.1804
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Echinococcus multilocularis orexin receptor type 2 0.0295 0.1077 0.1613
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.006 0.018 0.0173
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0019 0.0088
Loa Loa (eye worm) cytochrome P450 family protein 0.0111 0.0372 0.0365
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.0028 0.0056 0.0049
Echinococcus multilocularis rhodopsin orphan GPCR 0.0295 0.1077 0.1613
Loa Loa (eye worm) hypothetical protein 0.0028 0.0056 0.0049
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0586 0.2186 1
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0145 0.0502 0.0841
Treponema pallidum recombinase A 0.0109 0.0367 0.1679
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.003 0.0023
Schistosoma mansoni hypothetical protein 0.0312 0.1141 0.1911
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.006 0.018 0.0269
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0028 0.0056 0.0056
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.047 0.0787
Onchocerca volvulus 0.0129 0.0441 0.235
Loa Loa (eye worm) uncoordinated protein 58 0.0045 0.0121 0.0115
Schistosoma mansoni hypothetical protein 0.0051 0.0145 0.0243
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0252 0.1153
Echinococcus granulosus twik family of potassium channels 0.0045 0.0121 0.0203
Echinococcus multilocularis mothers against decapentaplegic 2 0.0018 0.0019 0.0029
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0051 0.0145 0.0145
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0028 0.0056 0.0083
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0295 0.1077 0.1804
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0097 0.0444
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0014 0.0023
Brugia malayi Serotonin receptor 0.0295 0.1077 0.1077
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0006 0.0162
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0051 0.0145 0.0212
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0909 0.416
Giardia lamblia Fructose-bisphosphate aldolase 0.0586 0.2186 1
Echinococcus multilocularis dnaJ subfamily B 0.0839 0.3155 0.4727
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0006 0.0162
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0084 0.0271 0.124
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Brugia malayi RNA, U transporter 1 0.0083 0.0267 0.0267
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0078 0.0078
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0144 0.0657
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0018 0.0087
Onchocerca volvulus 0.0071 0.0221 0.1157
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0045 0.0121 0.0121
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0136 0.047 0.0704
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.003 0.003
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0045 0.0123 0.0123
Echinococcus multilocularis histone acetyltransferase MYST2 0.0059 0.0175 0.0263
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.0075 0.0069
Echinococcus multilocularis neuropeptide s receptor 0.0295 0.1077 0.1613
Toxoplasma gondii hypothetical protein 0.0015 0.0006 0.0162
Loa Loa (eye worm) hypothetical protein 0.0197 0.0703 0.0697
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0579 0.2649
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0221 0.101
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0045 0.0121 0.0121
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.006 0.018 0.0301
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0015 0.0006 0.0011
Schistosoma mansoni peptidase Clp (S14 family) 0.0079 0.0252 0.0422
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0144 0.0657
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Echinococcus granulosus G protein coupled receptor 139 0.0295 0.1077 0.1804
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0213 0.0213
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0045 0.0123 0.0116
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Brugia malayi cytochrome P450 0.0051 0.0145 0.0145
Loa Loa (eye worm) MH2 domain-containing protein 0.0041 0.0105 0.0099
Schistosoma mansoni biogenic amine (5HT) receptor 0.1576 0.5969 1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0058 0.0171 0.0171
Onchocerca volvulus 0.0295 0.1077 0.5782
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0015 0.0006 0.0011
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.006 0.018 0.018
Mycobacterium ulcerans hypothetical protein 0.0024 0.0041 0.02
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0144 0.0137
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0045 0.0121 0.0121
Trichomonas vaginalis importin beta-1, putative 0.0024 0.004 0.0182
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Loa Loa (eye worm) hypothetical protein 0.0027 0.0054 0.0048
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0026 0.0043
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0097 0.0359
Schistosoma mansoni lipoxygenase 0.0056 0.0163 0.0273
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Echinococcus multilocularis G protein coupled receptor 139 0.0295 0.1077 0.1613
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0045 0.0121 0.0121
Echinococcus multilocularis twik family of potassium channels 0.0045 0.0121 0.0182
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.0075 0.0069
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0054 0.0053
Schistosoma mansoni calcium-activated potassium channel 0.0978 0.3687 0.6177
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0006 0.0189
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0136 0.047 0.0464
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.003 0.003
Brugia malayi Flap endonuclease-1 0.0055 0.0159 0.0159
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0136 0.047 0.0704
Schistosoma mansoni smad1 5 8 and 0.0041 0.0105 0.0177
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0295 0.1077 0.1804
Schistosoma mansoni polycystin 1-related 0.002 0.0026 0.0043
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0051 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0071 0.0221 0.0214
Brugia malayi MH1 domain containing protein 0.0041 0.0105 0.0105
Echinococcus granulosus neuropeptide Y receptor 0.0295 0.1077 0.1804
Leishmania major importin beta-1 subunit, putative 0.0024 0.004 0.004
Echinococcus multilocularis snurportin 1 0.0312 0.1141 0.1709
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0023 0.0105
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0051 0.0145 0.0212
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0586 0.2186 1
Schistosoma mansoni twik family of potassium channels-related 0.0045 0.0121 0.0203
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0221 0.101
Entamoeba histolytica pyruvate kinase, putative 0.0024 0.0039 0.0092
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.0221 0.0214
Loa Loa (eye worm) hypothetical protein 0.006 0.018 0.0173
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0295 0.1077 0.1804
Echinococcus multilocularis neuropeptides capa receptor 0.0295 0.1077 0.1613
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0089 0.0432
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0051 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Echinococcus multilocularis sex peptide receptor 0.0295 0.1077 0.1613
Loa Loa (eye worm) hypothetical protein 0.0028 0.0056 0.0049
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0129 0.0441 0.074
Brugia malayi AKH receptor 0.0295 0.1077 0.1077
Brugia malayi MH2 domain containing protein 0.06 0.2241 0.2241
Schistosoma mansoni hypothetical protein 0.0017 0.0015 0.0025
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0082 0.0172
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0095 0.031 0.0304
Echinococcus granulosus biogenic amine 5HT receptor 0.1576 0.5969 1
Leishmania major trypanothione reductase 0.0038 0.0096 0.0096
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0078 0.0359
Schistosoma mansoni voltage-gated potassium channel 0.0049 0.0137 0.023
Brugia malayi hypothetical protein 0.0295 0.1077 0.1077
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0295 0.1077 0.1077
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.0213 0.0213
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0006 0.0011
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0045 0.0121 0.0121
Onchocerca volvulus 0.0028 0.0056 0.0265
Echinococcus multilocularis nAChR subunit 0.0033 0.0073 0.011
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0144 0.0144
Onchocerca volvulus 0.0295 0.1077 0.5782
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0 0.0001
Schistosoma mansoni amine GPCR 0.0295 0.1077 0.1804
Plasmodium falciparum metacaspase-like protein 0.0019 0.0023 0.067
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0015 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.006 0.018 0.0173
Echinococcus multilocularis voltage gated potassium channel 0.0016 0.0009 0.0013
Onchocerca volvulus 0.0045 0.0121 0.062
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0015 0.0023
Echinococcus granulosus 7tm_1 domain containing protein 0.0295 0.1077 0.1804
Trichomonas vaginalis conserved hypothetical protein 0.0013 0 0.0001
Schistosoma mansoni sodium/chloride dependent transporter 0.0088 0.0286 0.048
Echinococcus granulosus serotonin receptor 0.0295 0.1077 0.1804
Loa Loa (eye worm) hypothetical protein 0.0028 0.0056 0.0049
Loa Loa (eye worm) hypothetical protein 0.0079 0.025 0.0243
Loa Loa (eye worm) hypothetical protein 0.0025 0.0044 0.0037
Echinococcus granulosus jumonji domain containing 1A 0.0033 0.0075 0.0126
Schistosoma mansoni hypothetical protein 0.002 0.0026 0.0043
Brugia malayi mothers against decapentaplegic homolog 3 0.0018 0.0019 0.0019
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0031 0.0917
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0015 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Loa Loa (eye worm) hypothetical protein 0.0111 0.0371 0.0365
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0015 0.044
Echinococcus granulosus somatostatin receptor 0.0295 0.1077 0.1804
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0045 0.0121 0.0554
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0031 0.0917
Trypanosoma cruzi cytochrome P450, putative 0.0088 0.0284 0.0284
Echinococcus granulosus neuropeptides capa receptor 0.0295 0.1077 0.1804
Brugia malayi intermediate filament protein 0.0113 0.0379 0.0379
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0097 0.0321 0.047
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0613 0.2805
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Trichomonas vaginalis conserved hypothetical protein 0.0013 0 0.0001
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0082 0.0264 0.1131
Brugia malayi mbt repeat family protein 0.0052 0.0148 0.0148
Echinococcus granulosus dna polymerase kappa 0.0021 0.003 0.005
Mycobacterium tuberculosis Conserved protein 0.0071 0.0221 0.0323
Loa Loa (eye worm) hypothetical protein 0.0037 0.0091 0.0085
Schistosoma mansoni DNA polymerase eta 0.0021 0.003 0.005
Echinococcus multilocularis neuropeptide Y receptor 0.0295 0.1077 0.1613
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0078 0.0072
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0034 0.0078 0.0078
Schistosoma mansoni loxhd1 0.002 0.0026 0.0043
Brugia malayi Intermediate filament tail domain containing protein 0.0113 0.0379 0.0379
Echinococcus multilocularis sodium and chloride dependent glycine 0.0015 0.0006 0.001
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0059 0.0175 0.0294
Echinococcus multilocularis rhodopsin orphan GPCR 0.0295 0.1077 0.1613
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0051 0.0145 0.0707
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0015 0.0009
Echinococcus multilocularis neuropeptide receptor 0.0295 0.1077 0.1613
Onchocerca volvulus 0.0088 0.0286 0.1512
Onchocerca volvulus 0.0024 0.0041 0.0187
Loa Loa (eye worm) hypothetical protein 0.0071 0.0221 0.0214
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0097 0.0145
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0054 0.1564
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0045 0.0121 0.0121
Leishmania major DNA polymerase eta, putative 0.0021 0.003 0.003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0586 0.2186 1
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.003 0.0065 0.0065
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0082 0.0119
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0041 0.02
Loa Loa (eye worm) hypothetical protein 0.006 0.018 0.0173
Schistosoma mansoni phd/f-box containing protein 0.0033 0.0075 0.0126
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0019 0.0023 0.0038
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0015 0.0015
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.006 0.018 0.0173
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0016 0.0009 0.0009
Brugia malayi glutaminase DH11.1 0.055 0.205 0.205
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0124 0.0422 0.0632
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0023 0.0105
Schistosoma mansoni nAChR subunit 0.006 0.018 0.0301
Echinococcus multilocularis neuropeptides capa receptor 0.0295 0.1077 0.1613
Schistosoma mansoni hypothetical protein 0.0295 0.1077 0.1804
Mycobacterium leprae Conserved hypothetical protein 0.0642 0.24 1
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0089 0.0089
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0144 0.0215
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0 0.0001
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0045 0.0121 0.0121
Giardia lamblia Flap structure-specific endonuclease 0.0055 0.0159 0.0725
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0197 0.0703 0.0703
Schistosoma mansoni amine GPCR 0.0295 0.1077 0.1804
Schistosoma mansoni adenoreceptor 0.0295 0.1077 0.1804
Mycobacterium tuberculosis Probable oxidoreductase 0.0097 0.0321 0.047
Brugia malayi Importin beta-1 subunit 0.0029 0.0061 0.0061
Onchocerca volvulus 0.0064 0.0194 0.1013
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Echinococcus multilocularis glycine receptor subunit alpha 1 0.006 0.018 0.0269
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0051 0.0145 0.0145
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.006 0.018 0.018
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0009 0.0014
Echinococcus granulosus lysine specific demethylase 5A 0.0127 0.0435 0.0728
Echinococcus granulosus importin subunit beta 1 0.0029 0.0061 0.0102
Brugia malayi Muscleblind-like protein 0.0161 0.0566 0.0566
Schistosoma mansoni jumonji/arid domain-containing protein 0.0127 0.0435 0.0728
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0127 0.0436 0.073
Plasmodium vivax potassium channel, putative 0.0045 0.0121 0.3539
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0016 0.0454
Loa Loa (eye worm) hypothetical protein 0.0059 0.0175 0.0169
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0002
Brugia malayi neuropeptide F receptor 0.0295 0.1077 0.1077
Echinococcus granulosus pyruvate kinase 0.0034 0.0078 0.0131
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0011
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Onchocerca volvulus 0.002 0.0026 0.0103
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Schistosoma mansoni Smad4 0.0018 0.0019 0.0032
Trypanosoma cruzi DNA repair protein, putative 0.0034 0.0078 0.0078
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0015 0.0378
Loa Loa (eye worm) TWK-28 protein 0.0045 0.0121 0.0115
Echinococcus granulosus dnaJ subfamily B 0.0839 0.3155 0.5286
Schistosoma mansoni calcium-activated potassium channel 0.0045 0.0121 0.0203
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0295 0.1077 0.1804
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.0171 0.0171
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0015 0.0008
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.0157 0.0151
Echinococcus granulosus g-protein coupled receptor 0.0295 0.1077 0.1804
Loa Loa (eye worm) cytochrome P450 family protein 0.0088 0.0284 0.0278
Loa Loa (eye worm) hypothetical protein 0.0024 0.0041 0.0035
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0031 0.0067 0.0067
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0089 0.0133
Echinococcus granulosus tm gpcr rhodopsin 0.0295 0.1077 0.1804
Schistosoma mansoni lamin 0.0113 0.0379 0.0635
Schistosoma mansoni growth hormone secretagogue receptor 0.0295 0.1077 0.1804
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0197 0.0703 0.1178
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0213 0.0213
Onchocerca volvulus 0.0071 0.0221 0.1157
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0197 0.0703 0.1053
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0295 0.1077 0.5782
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.0096 0.0089
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0051 0.0145 0.0145
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0041 0.0105 0.0177
Brugia malayi MAP kinase sur-1 0.0051 0.0144 0.0144
Loa Loa (eye worm) MH2 domain-containing protein 0.06 0.2241 0.2236
Onchocerca volvulus 0.006 0.018 0.0936
Plasmodium vivax SET domain protein, putative 0.0064 0.0194 0.5668
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0221 0.037
Onchocerca volvulus 0.0295 0.1077 0.5782
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0033 0.0075 0.1891
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0098 0.2871
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Plasmodium vivax potassium channel, putative 0.0045 0.0121 0.3539
Brugia malayi jmjC domain containing protein 0.0033 0.0075 0.0075
Brugia malayi Carboxylesterase family protein 0.0066 0.0202 0.0202
Trichomonas vaginalis conserved hypothetical protein 0.0013 0 0.0001
Echinococcus multilocularis twik family of potassium channels 0.0045 0.0121 0.0182
Schistosoma mansoni hypothetical protein 0.1201 0.4538 0.7602
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Brugia malayi Melatonin receptor type 1A 0.0295 0.1077 0.1077
Echinococcus granulosus GPCR family 2 0.0017 0.0015 0.0025
Echinococcus granulosus histone lysine methyltransferase setb 0.0064 0.0194 0.0325
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0295 0.1077 0.1071
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0051 0.0145 0.0212
Plasmodium falciparum metacaspase 1 0.0019 0.0023 0.067
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0 0.0001
Onchocerca volvulus 0.0033 0.0073 0.0362
Echinococcus multilocularis acetylcholinesterase 0.0066 0.0202 0.0303
Echinococcus multilocularis 0.0051 0.0145 0.0217
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0041 0.01
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0015 0.0006 0.0011
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0009 0.0014
Brugia malayi hypothetical protein 0.0028 0.0056 0.0056
Schistosoma mansoni neurotransmitter gated ion channel 0.0028 0.0056 0.0093
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0045 0.0121 0.0121
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0095 0.031 0.1419
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0028 0.0056 0.0093
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0056 0.0163 0.0273
Echinococcus multilocularis rhodopsin orphan GPCR 0.0295 0.1077 0.1613
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Echinococcus granulosus voltage gated potassium channel 0.0016 0.0009 0.0014
Echinococcus granulosus lamin 0.0113 0.0379 0.0635
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0174 0.0168
Brugia malayi hypothetical protein 0.0039 0.0098 0.0098
Schistosoma mansoni neuropeptide F-like receptor 0.0295 0.1077 0.1804
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0197 0.0703 0.1178
Brugia malayi hypothetical protein 0.0015 0.0006 0.0006
Echinococcus multilocularis caspase 2 0.0098 0.0323 0.0484
Echinococcus multilocularis neuropeptide receptor A26 0.0295 0.1077 0.1613
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.006 0.018 0.0269
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0051 0.0145 0.0212
Brugia malayi Thioredoxin reductase 0.0038 0.0096 0.0096
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0023 0.067
Brugia malayi isocitrate dehydrogenase 0.0017 0.0015 0.0015
Brugia malayi hypothetical protein 0.0079 0.025 0.025
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0103 0.0342 0.1566
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0061 0.0091
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0 0.0001
Echinococcus multilocularis somatostatin receptor 0.0295 0.1077 0.1613
Loa Loa (eye worm) melatonin receptor type 1A 0.0295 0.1077 0.1071
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.006 0.018 0.0301
Schistosoma mansoni myelin transcription factor 1 myt1 0.0059 0.0175 0.0294
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Echinococcus multilocularis allatostatin A receptor 0.0295 0.1077 0.1613
Plasmodium vivax JmjC domain containing protein 0.0033 0.0075 0.2199
Echinococcus granulosus cytochrome P450 2K1 0.0051 0.0145 0.0243
Echinococcus granulosus carboxylesterase 5A 0.0066 0.0202 0.0339
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.003 0.003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0586 0.2186 1
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0095 0.031 0.1513
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0028 0.0042
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0018 0.0521
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0295 0.1077 0.1804
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.003 0.0136
Echinococcus multilocularis mothers against decapentaplegic 6 0.0018 0.0019 0.0029
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0041 0.02
Leishmania major ion transport protein-like protein 0.0045 0.0121 0.0121
Echinococcus multilocularis neuropeptide receptor 0.0295 0.1077 0.1613
Trypanosoma cruzi metacaspase 5, putative 0.0019 0.0023 0.0023
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0019 0.0094
Schistosoma mansoni sex comb on midleg homolog 0.0052 0.0148 0.0248
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Schistosoma mansoni voltage-gated potassium channel 0.0049 0.0137 0.023
Giardia lamblia Pyruvate kinase 0.0017 0.0016 0.0071
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0033 0.0073 0.0123
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0041 0.0105 0.0158
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.006 0.018 0.018
Trypanosoma brucei unspecified product 0.0021 0.003 0.003
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0295 0.1077 0.1077
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0051 0.0145 0.0212
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0097 0.2437
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0252 0.1229
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0054 0.0245
Entamoeba histolytica hypothetical protein 0.0102 0.034 0.1479
Echinococcus multilocularis glycine receptor subunit alpha 1 0.006 0.018 0.0269
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0295 0.1077 0.1804
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0112 0.2809
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.006 0.018 0.0173
Loa Loa (eye worm) hypothetical protein 0.006 0.018 0.0173
Loa Loa (eye worm) glutaminase 0.055 0.205 0.2045
Loa Loa (eye worm) hypothetical protein 0.006 0.018 0.0173
Plasmodium falciparum pyruvate kinase 0.0034 0.0078 0.229
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0295 0.1077 0.1804
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0041 0.01
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0102 0.0153
Echinococcus multilocularis pyruvate kinase 0.0017 0.0016 0.0023
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0058 0.0171 0.0251
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0041 0.02
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0295 0.1077 0.1804
Echinococcus multilocularis cpg binding protein 0.0062 0.0187 0.028
Trypanosoma cruzi ion transport protein, putative 0.0045 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0028 0.0056 0.0049
Echinococcus multilocularis musashi 0.0113 0.0379 0.0568
Brugia malayi G protein-coupled receptor F59B2.13 0.0295 0.1077 0.1077
Mycobacterium ulcerans transmembrane cation transporter 0.0045 0.0121 0.0591
Brugia malayi hypothetical protein 0.0018 0.0017 0.0017
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0579 0.2649
Loa Loa (eye worm) hypothetical protein 0.006 0.018 0.0173
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0023 0.0105
Loa Loa (eye worm) hypothetical protein 0.0064 0.0194 0.0188
Echinococcus granulosus rhodopsin orphan GPCR 0.0295 0.1077 0.1804
Echinococcus multilocularis rhodopsin orphan GPCR 0.0295 0.1077 0.1613
Mycobacterium tuberculosis Conserved protein 0.0071 0.0221 0.0323
Loa Loa (eye worm) hypothetical protein 0.033 0.1208 0.1202
Entamoeba histolytica hypothetical protein 0.0039 0.0098 0.0362
Leishmania major calcium/potassium channel (CAKC), putative 0.0045 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.006 0.018 0.0173
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.006 0.018 0.0173
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0062 0.0185 0.4648
Loa Loa (eye worm) hypothetical protein 0.0028 0.0056 0.0049
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0028 0.0056 0.0049
Echinococcus granulosus rhodopsin orphan GPCR 0.0295 0.1077 0.1804
Echinococcus granulosus neuropeptide FF receptor 2 0.0295 0.1077 0.1804
Plasmodium falciparum amino acid transporter, putative 0.0015 0.0006 0.0189
Echinococcus multilocularis glycine receptor subunit alpha 1 0.006 0.018 0.0269
Echinococcus granulosus rhodopsin orphan GPCR 0.0295 0.1077 0.1804
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.0075 0.0069
Brugia malayi hypothetical protein 0.0295 0.1077 0.1077
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0045 0.0121 0.0121
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0251 0.0909 0.0903
Loa Loa (eye worm) hypothetical protein 0.0028 0.0056 0.0049
Trypanosoma cruzi cytochrome P450, putative 0.0088 0.0284 0.0284
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0041 0.0041
Echinococcus multilocularis phd:f box containing protein 0.0033 0.0075 0.0113
Plasmodium vivax metacaspase 1, putative 0.0019 0.0023 0.067
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0036 0.0088 0.0132
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.0156 0.015
Loa Loa (eye worm) hypothetical protein 0.0082 0.0264 0.0258
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.004 0.0182
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0083 0.0268 0.0449
Schistosoma mansoni neuropeptide receptor 0.0295 0.1077 0.1804
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0909 0.416
Brugia malayi Cytochrome P450 family protein 0.0051 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0033 0.0073 0.0067
Leishmania major pyruvate kinase 0.0034 0.0078 0.0078
Brugia malayi hypothetical protein 0.0027 0.0054 0.0054
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0045 0.0121 0.0115
Schistosoma mansoni amine GPCR 0.066 0.2471 0.414
Echinococcus multilocularis neuropeptide Y receptor 0.0295 0.1077 0.1613
Schistosoma mansoni hypothetical protein 0.0017 0.0015 0.0025
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0019 0.0023 0.0034
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0054 0.0157 0.0263
Echinococcus multilocularis g protein coupled receptor 0.0295 0.1077 0.1613
Echinococcus granulosus cpg binding protein 0.0062 0.0187 0.0314
Loa Loa (eye worm) beta-lactamase 0.0071 0.0221 0.0214
Brugia malayi MH2 domain containing protein 0.0041 0.0105 0.0105
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0083 0.0268 0.0401
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.0221 0.037
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0088 0.0284 0.1385
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0295 0.1077 0.1077
Brugia malayi hypothetical protein 0.0295 0.1077 0.1077
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0121 0.0121
Schistosoma mansoni pyruvate kinase 0.0017 0.0016 0.0026
Trypanosoma cruzi metacaspase, putative 0.0019 0.0023 0.0023
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0023 0.0105
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0019 0.0032
Brugia malayi beta-lactamase 0.0071 0.0221 0.0221
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.006 0.018 0.0301
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0051 0.0142 0.0651
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0295 0.1077 0.1613
Schistosoma mansoni pyruvate kinase 0.0034 0.0078 0.0131
Echinococcus multilocularis rhodopsin orphan GPCR 0.0295 0.1077 0.1613
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Brugia malayi Probable ClpP-like protease 0.0079 0.0252 0.0252
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.0033 0.0073 0.0067
Echinococcus multilocularis acetylcholinesterase 0.0066 0.0202 0.0303
Echinococcus granulosus voltage dependent calcium channel 0.0031 0.0067 0.0112
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0098 0.0164
Brugia malayi hypothetical protein 0.0165 0.0581 0.0581
Echinococcus granulosus g protein coupled receptor 0.0295 0.1077 0.1804
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.006 0.018 0.018
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0045 0.0121 0.0121
Brugia malayi hypothetical protein 0.0045 0.0121 0.0121
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0295 0.1077 0.1613
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0051 0.0145 0.0707
Plasmodium vivax glutathione reductase, putative 0.0038 0.0096 0.2795
Leishmania major cytochrome p450-like protein 0.0051 0.0145 0.0145
Schistosoma mansoni hypothetical protein 0.0039 0.0098 0.0164
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0079 0.0252 0.6866
Brugia malayi GnHR receptor homolog 0.0295 0.1077 0.1077
Onchocerca volvulus 0.0059 0.0174 0.0907
Schistosoma mansoni nAChR subunit 0.006 0.018 0.0301
Trichomonas vaginalis conserved hypothetical protein 0.0013 0 0.0001
Echinococcus granulosus alpha 1A adrenergic receptor 0.0295 0.1077 0.1804
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0066 0.0202 0.0196
Toxoplasma gondii hypothetical protein 0.0027 0.0054 0.1345
Echinococcus granulosus potassium channel subfamily K 8 0.0045 0.0121 0.0203
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0033 0.0075 0.0075
Echinococcus granulosus neuropeptides capa receptor 0.0295 0.1077 0.1804
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0124 0.0422 0.0707
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0295 0.1077 0.1804
Leishmania major hypothetical protein, conserved 0.0071 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Echinococcus granulosus caspase 0.0019 0.0023 0.0038
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0045 0.0121 0.0121
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.006 0.018 0.018
Trichomonas vaginalis esterase, putative 0.0071 0.0221 0.101
Echinococcus granulosus acetylcholinesterase 0.0066 0.0202 0.0339
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0026 0.0747
Echinococcus granulosus allatostatin A receptor 0.0295 0.1077 0.1804
Echinococcus multilocularis pyruvate kinase 0.0027 0.0051 0.0077
Echinococcus granulosus peptide allatostatin:somatostatin 0.0295 0.1077 0.1804
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0015 0.0015
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0031 0.0053
Plasmodium falciparum potassium channel 0.0045 0.0121 0.3539
Brugia malayi Carboxylesterase family protein 0.0066 0.0202 0.0202
Echinococcus multilocularis potassium channel subfamily K 0.0045 0.0121 0.0182
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0136 0.047 0.047
Echinococcus granulosus geminin 0.1201 0.4538 0.7602
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0019 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0005 0.0005
Trypanosoma brucei unspecified product 0.0015 0.0005 0.0005
Echinococcus multilocularis lamin 0.0113 0.0379 0.0568
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.0096 0.014
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.018 0.0302
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0051 0.0145 0.0212
Brugia malayi jmjC domain containing protein 0.0127 0.0435 0.0435
Loa Loa (eye worm) hypothetical protein 0.006 0.018 0.0173
Loa Loa (eye worm) hypothetical protein 0.0036 0.0088 0.0082
Schistosoma mansoni nAChR subunit 0.006 0.018 0.0301
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0026 0.0038
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Echinococcus multilocularis pyruvate kinase 0.0034 0.0078 0.0117
Mycobacterium ulcerans pyruvate kinase 0.0034 0.0078 0.0382
Loa Loa (eye worm) ACC-1 protein 0.006 0.018 0.0173
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0194 0.0325
Loa Loa (eye worm) hypothetical protein 0.0098 0.0323 0.0317
Echinococcus granulosus rhodopsin orphan GPCR 0.0295 0.1077 0.1804
Echinococcus multilocularis geminin 0.1201 0.4538 0.6798
Echinococcus multilocularis dna polymerase eta 0.0021 0.003 0.0044
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.0221 0.0221
Trichomonas vaginalis conserved hypothetical protein 0.0013 0 0.0001
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0144 0.0241
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0015 0.0015
Trypanosoma brucei trypanothione reductase 0.0038 0.0096 0.0096
Plasmodium falciparum flap endonuclease 1 0.0055 0.0159 0.463
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Schistosoma mansoni ap endonuclease 0.0018 0.0019 0.0032
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0096 0.0096
Mycobacterium tuberculosis Probable dehydrogenase 0.0087 0.0283 0.0415
Echinococcus multilocularis serotonin transporter 0.0088 0.0286 0.0429
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0121 0.0121
Schistosoma mansoni twik family of potassium channels-related 0.0045 0.0121 0.0203
Loa Loa (eye worm) hypothetical protein 0.0052 0.0148 0.0142
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0113 0.0379 0.0373
Leishmania major cytochrome p450-like protein 0.0051 0.0145 0.0145
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0052 0.0148 0.0248
Onchocerca volvulus 0.006 0.018 0.0936
Onchocerca volvulus 0.0295 0.1077 0.5782
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0295 0.1077 0.1804
Trichomonas vaginalis ran, putative 0.0022 0.0031 0.0144
Loa Loa (eye worm) hypothetical protein 0.0033 0.0073 0.0067
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.003 0.0145
Leishmania major GTP-binding protein, putative 0.0022 0.0031 0.0031
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.0213 0.0357
Loa Loa (eye worm) hypothetical protein 0.0054 0.0157 0.0151
Loa Loa (eye worm) hypothetical protein 0.0024 0.0039 0.0033
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0045 0.0121 0.0203
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0098 0.0364
Echinococcus multilocularis neuropeptide FF receptor 2 0.0295 0.1077 0.1613
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0028 0.0021
Echinococcus granulosus tm gpcr rhodopsin 0.0295 0.1077 0.1804
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0221 0.101
Schistosoma mansoni histamine h1 receptor 0.0295 0.1077 0.1804
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0016 0.0009 0.0013
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Loa Loa (eye worm) acetylcholine receptor protein 0.0028 0.0056 0.0049
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.0096 0.2795
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Schistosoma mansoni nAChR subunit 0.006 0.018 0.0301
Brugia malayi MH1 domain containing protein 0.0041 0.0105 0.0105
Onchocerca volvulus Neuropeptide F receptor homolog 0.0295 0.1077 0.5782
Trypanosoma brucei unspecified product 0.0015 0.0005 0.0005
Schistosoma mansoni rab6-interacting 0.002 0.0026 0.0043
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0295 0.1077 0.1804
Trichomonas vaginalis flap endonuclease-1, putative 0.0055 0.0159 0.0725
Chlamydia trachomatis pyruvate kinase 0.0034 0.0078 0.2136
Brugia malayi hypothetical protein 0.0295 0.1077 0.1077
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0586 0.2186 1
Echinococcus granulosus fmrfamide receptor 0.0295 0.1077 0.1804
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0041 0.0041
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0061 0.0061
Schistosoma mansoni hypothetical protein 0.0295 0.1077 0.1804
Brugia malayi hypothetical protein 0.0295 0.1077 0.1077
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0051 0.0145 0.0212
Loa Loa (eye worm) hypothetical protein 0.0031 0.0067 0.0061
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0051 0.0145 0.0707
Echinococcus multilocularis serotonin receptor 0.1576 0.5969 0.8942
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0019 0.0019
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0295 0.1077 0.1077
Loa Loa (eye worm) hypothetical protein 0.0033 0.0073 0.0067
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0028 0.0056 0.0056
Onchocerca volvulus 0.0295 0.1077 0.5782
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0015 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.003 0.003
Schistosoma mansoni caspase-3 (C14 family) 0.0019 0.0023 0.0038
Onchocerca volvulus 0.0295 0.1077 0.5782
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0051 0.0145 0.0707
Loa Loa (eye worm) hypothetical protein 0.0129 0.0441 0.0435
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0045 0.0121 0.047
Loa Loa (eye worm) intermediate filament protein 0.0113 0.0379 0.0373
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0051 0.0145 0.0707
Trichomonas vaginalis conserved hypothetical protein 0.0013 0 0.0001
Echinococcus granulosus g protein coupled receptor 0.0295 0.1077 0.1804
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.0221 0.0323
Echinococcus multilocularis sodium and chloride dependent glycine 0.0015 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0056 0.0049
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0045 0.0121 0.0121
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0097 0.0473
Loa Loa (eye worm) glutaminase 2 0.055 0.205 0.2045
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0295 0.1077 0.1804
Brugia malayi Pyruvate kinase, M2 isozyme 0.0034 0.0078 0.0078
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0144 0.0215
Plasmodium vivax amine transporter, putative 0.0015 0.0006 0.0189
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0014 0.0021
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0454 0.1684 0.2467
Mycobacterium leprae conserved hypothetical protein 0.0071 0.0221 0.0762
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0014 0.0023
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0019 0.0019
Onchocerca volvulus 0.0028 0.0056 0.0265
Schistosoma mansoni Smad4 0.0041 0.0105 0.0177
Loa Loa (eye worm) GABA receptor subunit 0.0033 0.0073 0.0067
Echinococcus multilocularis serotonin receptor 0.1576 0.5969 0.8942
Echinococcus granulosus pyruvate kinase 0.0034 0.0078 0.0131
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0045 0.0121 0.0121
Schistosoma mansoni nAChR subunit 0.006 0.018 0.0301
Loa Loa (eye worm) Smad1 0.0041 0.0105 0.0099
Loa Loa (eye worm) hypothetical protein 0.0024 0.0041 0.0035
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0029
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0033 0.0074 0.0109
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.0213 0.0895
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0051 0.0145 0.0707
Echinococcus granulosus glycine receptor subunit beta 0.006 0.018 0.0301
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0295 0.1077 0.1071
Loa Loa (eye worm) flap endonuclease-1 0.0055 0.0159 0.0152
Toxoplasma gondii histone lysine methyltransferase SET1 0.0117 0.0398 1
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0031 0.0789
Echinococcus multilocularis calcium activated potassium channel variant 0.0045 0.0121 0.0182
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.006 0.018 0.0269
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0015 0.0006 0.0176
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0019 0.0029
Brugia malayi ORL1-like opioid receptor 0.0295 0.1077 0.1077
Schistosoma mansoni caspase-7 (C14 family) 0.0098 0.0323 0.0541
Loa Loa (eye worm) hypothetical protein 0.0165 0.0581 0.0575
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.003 0.003
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0031 0.0047
Toxoplasma gondii exonuclease III APE 0.0018 0.0019 0.0485
Onchocerca volvulus Putative nachr subunit 0.0197 0.0703 0.3763
Entamoeba histolytica hypothetical protein 0.0024 0.004 0.0094
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0031 0.0031
Echinococcus granulosus dna polymerase eta 0.0021 0.003 0.005
Loa Loa (eye worm) hypothetical protein 0.0079 0.0252 0.0246
Echinococcus granulosus caspase 2 0.0098 0.0323 0.0541
Loa Loa (eye worm) TWK-7 protein 0.0045 0.0121 0.0115
Trichomonas vaginalis set domain proteins, putative 0.05 0.1858 0.8499
Brugia malayi Dopamine receptor protein 2 0.0295 0.1077 0.1077
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Brugia malayi Dopamine receptor protein 1 0.115 0.434 0.434
Echinococcus multilocularis G-protein coupled receptor, putative 0.0295 0.1077 0.1613
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0359 0.1322 0.6011
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.006 0.018 0.0173
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0213 0.0213
Brugia malayi MH1 domain containing protein 0.0023 0.0036 0.0036
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.0171 0.0836
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0083 0.0268 0.0449
Echinococcus granulosus biogenic amine 5HT receptor 0.0673 0.2521 0.4224
Loa Loa (eye worm) LGC-31 protein 0.006 0.018 0.0173
Brugia malayi Cytochrome P450 family protein 0.0111 0.0372 0.0372
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0051 0.0145 0.0212
Schistosoma mansoni opsin-like receptor 0.0295 0.1077 0.1804
Echinococcus granulosus muscleblind protein 0.0161 0.0566 0.0948
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0013 0 0.0001
Brugia malayi MH2 domain containing protein 0.0018 0.0019 0.0019
Mycobacterium ulcerans glutaminase 0.055 0.205 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.006 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0033 0.0073 0.0067
Echinococcus granulosus histone acetyltransferase MYST2 0.0059 0.0175 0.0294
Mycobacterium ulcerans beta-lactamase 0.0071 0.0221 0.1077
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1761 0.6675 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0019 0.0013
Schistosoma mansoni phosphatidylserine receptor 0.0033 0.0075 0.0126
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0051 0.0145 0.0707
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0019 0.0564
Echinococcus multilocularis thioredoxin glutathione reductase 0.0039 0.0098 0.0146
Loa Loa (eye worm) hypothetical protein 0.2631 1 1
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0095 0.031 0.031
Schistosoma mansoni protein phosphatase 2C 0.0033 0.0075 0.0126
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0295 0.1077 0.1804
Trichomonas vaginalis helicase, putative 0.0013 0 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0041 0.02
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0059 0.0175 0.0263
Schistosoma mansoni amine GPCR 0.0295 0.1077 0.1804
Loa Loa (eye worm) hypothetical protein 0.0028 0.0056 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.003 0.003
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0031 0.0031
Trypanosoma brucei pyruvate kinase 1, putative 0.0034 0.0078 0.0078
Brugia malayi putative neuropeptide receptor 0.0295 0.1077 0.1077
Onchocerca volvulus 0.0113 0.0379 0.2014
Echinococcus multilocularis pyruvate kinase 0.0017 0.0016 0.0023
Mycobacterium ulcerans ion transport protein 0.0045 0.0121 0.0591
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0019 0.0023 0.0038
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.0221 0.0331
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0019 0.0013
Schistosoma mansoni caspase-7 (C14 family) 0.0019 0.0023 0.0038
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0586 0.2186 1
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.003 0.003
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0052 0.0148 0.0216
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.0023
Brugia malayi Cation transporter family protein 0.006 0.018 0.018
Mycobacterium ulcerans lipase LipD 0.0071 0.0221 0.1077
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0054 0.1584
Echinococcus multilocularis lysine specific demethylase 6a 0.0033 0.0075 0.0113
Loa Loa (eye worm) cytochrome P450 family protein 0.0088 0.0284 0.0278
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0978 0.3687 0.3683
Onchocerca volvulus 0.033 0.1208 0.649
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0051 0.0145 0.0707
Leishmania major hypothetical protein, conserved 0.0033 0.0075 0.0075
Loa Loa (eye worm) MBCTL1 0.0059 0.0175 0.0169
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.003 0.003
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0033 0.0075 0.0075
Schistosoma mansoni single-minded 0.0049 0.0138 0.023
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0041 0.006
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0051 0.0145 0.0212
Schistosoma mansoni intermediate filament proteins 0.0113 0.0379 0.0635
Onchocerca volvulus 0.002 0.0026 0.0103
Echinococcus granulosus glycine receptor subunit alpha 1 0.006 0.018 0.0301
Toxoplasma gondii ion channel protein 0.0045 0.0121 0.3044
Trypanosoma brucei metacaspase MCA2 0.0019 0.0023 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0005 0.0005
Echinococcus multilocularis polycomb protein SCMH1 0.0052 0.0148 0.0222
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0019 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Echinococcus multilocularis microtubule associated protein 2 0.1394 0.5275 0.7902
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0031 0.0031
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0051 0.0145 0.0707
Echinococcus granulosus JmjC domain containing protein 4 0.0033 0.0075 0.0126
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Schistosoma mansoni pyruvate kinase 0.0034 0.0078 0.0131
Schistosoma mansoni sodium/chloride dependent transporter 0.0015 0.0006 0.0011
Schistosoma mansoni neuropeptide receptor 0.0295 0.1077 0.1804
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Brugia malayi hypothetical protein 0.0045 0.0121 0.0121
Echinococcus multilocularis GPCR, family 2 0.0017 0.0015 0.0022
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0045 0.0123 0.0184
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.0171 0.0836
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0286 0.1042 0.4243
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0194 0.0325
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0087 0.0283 0.0415
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0144 0.3608
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0028 0.0046
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.003 0.003
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0295 0.1077 0.1071
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0095 0.031 0.8454
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0079 0.0252 0.736
Brugia malayi mbt repeat family protein 0.0052 0.0148 0.0148
Loa Loa (eye worm) nuclear factor I 0.0023 0.0036 0.0029
Onchocerca volvulus 0.0045 0.0121 0.062
Onchocerca volvulus 0.0113 0.0379 0.2014
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0045 0.0121 0.0178
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.003 0.0043
Echinococcus multilocularis Smad4 0.0041 0.0105 0.0158
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0051 0.0145 0.0212
Echinococcus multilocularis caspase 8 0.0019 0.0023 0.0034
Plasmodium falciparum glutathione reductase 0.0038 0.0096 0.2795
Schistosoma mansoni microtubule-associated protein tau 0.1394 0.5275 0.8837
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0079 0.0252 0.0378
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0006 0.0011
Schistosoma mansoni twik family of potassium channels-related 0.0045 0.0121 0.0203
Trichomonas vaginalis conserved hypothetical protein 0.0013 0 0.0001
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0078 0.0389
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0014 0.0021
Leishmania major C-8 sterol isomerase-like protein 0.2631 1 1
Schistosoma mansoni nAChR subunit 0.006 0.018 0.0301
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0015 0.0023
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0054 0.1564
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0087 0.0283 0.0415
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.003 0.0043
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0062 0.0185 0.0902
Schistosoma mansoni importin beta-1 0.0029 0.0061 0.0102
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0045 0.0121 0.0121
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.006 0.018 0.018
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0078 0.0072
Loa Loa (eye worm) jmjC domain-containing protein 0.0127 0.0435 0.0429
Echinococcus granulosus lysine specific demethylase 6a 0.0033 0.0075 0.0126
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0439 0.1627 0.1621
Loa Loa (eye worm) carboxylesterase 0.0066 0.0202 0.0196
Echinococcus granulosus twik family of potassium channels 0.0045 0.0121 0.0203
Loa Loa (eye worm) hypothetical protein 0.0066 0.0202 0.0196
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0045 0.0121 0.0121
Echinococcus granulosus sodium and chloride dependent glycine 0.0015 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0033 0.0075 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0023 0.0105
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.003 0.0044
Brugia malayi follicle stimulating hormone receptor 0.0295 0.1077 0.1077
Brugia malayi RE15519p 0.0295 0.1077 0.1077
Loa Loa (eye worm) hypothetical protein 0.0071 0.0221 0.0214
Schistosoma mansoni twik family of potassium channels-related 0.0045 0.0121 0.0203
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0109 0.0367 1
Brugia malayi excitatory GABA receptor EXP-1A 0.006 0.018 0.018
Echinococcus granulosus mothers against decapentaplegic 6 0.0018 0.0019 0.0032
Onchocerca volvulus 0.0129 0.0441 0.235
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0129 0.0441 0.074
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0295 0.1077 0.1613
Leishmania major pyruvate kinase 0.0034 0.0078 0.0078
Loa Loa (eye worm) mbt repeat family protein 0.0052 0.0148 0.0142
Echinococcus granulosus glycine receptor subunit beta 0.006 0.018 0.0301
Toxoplasma gondii ABC1 family protein 0.0071 0.0221 0.5545
Onchocerca volvulus 0.0079 0.025 0.1313
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.003 0.005
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0041 0.0041
Echinococcus granulosus calcium activated potassium channel variant 0.0045 0.0121 0.0203
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0221 0.101
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0097 0.0097
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0055 0.0159 0.0159
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0015 0.0023
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0055 0.0159 0.0159
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0041 0.0041
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0295 0.1077 0.1613
Brugia malayi PAS domain containing protein 0.0049 0.0138 0.0138
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0112 0.0512
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.0221 0.0323
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0252 0.6866
Trypanosoma brucei calcium-activated potassium channel, putative 0.0045 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0011
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0028 0.0056 0.0056
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0023 0.0105
Onchocerca volvulus 0.0045 0.0121 0.062
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0051 0.0145 0.0212
Schistosoma mansoni nAChR subunit 0.0028 0.0056 0.0093
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0016 0.039
Brugia malayi beta-lactamase family protein 0.0071 0.0221 0.0221
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0295 0.1077 0.1613
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0028 0.0056 0.0049
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0144 0.0144
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0015 0.0023
Echinococcus multilocularis small conductance calcium activated potassium 0.0978 0.3687 0.5523
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.006 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0011
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0252 0.736
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0091 0.0091
Schistosoma mansoni jumonji domain containing protein 0.0033 0.0075 0.0126
Loa Loa (eye worm) hypothetical protein 0.006 0.018 0.0173
Schistosoma mansoni myosin xvIII 0.0295 0.1077 0.1804
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0095 0.031 0.0465
Loa Loa (eye worm) MH1 domain-containing protein 0.0041 0.0105 0.0099
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0033 0.0073 0.0073
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0015 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0071 0.0221 0.0214
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Echinococcus multilocularis g protein coupled receptor 0.0295 0.1077 0.1613
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0023 0.0105
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0295 0.1077 0.1804
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0033 0.0075 0.1891
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0015 0.0022
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0083 0.0268 0.0449
Loa Loa (eye worm) hypothetical protein 0.0033 0.0073 0.0067
Brugia malayi Serotonin receptor 0.0295 0.1077 0.1077
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0097 0.0163
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0087 0.0283 0.1027
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.0213 0.0357
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0112 0.0512
Echinococcus granulosus mothers against decapentaplegic 2 0.0018 0.0019 0.0032
Loa Loa (eye worm) hypothetical protein 0.0033 0.0073 0.0067
Entamoeba histolytica hypothetical protein 0.0039 0.0098 0.0362
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0023 0.0105
Onchocerca volvulus 0.0295 0.1077 0.5782
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Schistosoma mansoni inositol monophosphatase 0.0039 0.0097 0.0163
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.003 0.003
Trypanosoma brucei C-8 sterol isomerase, putative 0.2631 1 1
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0041 0.006
Loa Loa (eye worm) hypothetical protein 0.0054 0.0157 0.015
Schistosoma mansoni jumonji domain containing protein 0.0124 0.0422 0.0707
Loa Loa (eye worm) hypothetical protein 0.0113 0.0379 0.0373
Echinococcus granulosus glycine receptor subunit alpha 1 0.006 0.018 0.0301
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0051 0.0145 0.0212
Loa Loa (eye worm) hypothetical protein 0.0033 0.0075 0.0069
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0087 0.0283 0.0415
Echinococcus multilocularis muscleblind protein 0.0161 0.0566 0.0848
Echinococcus multilocularis pyruvate kinase 0.0017 0.0016 0.0023
Schistosoma mansoni cpg binding protein 0.0062 0.0187 0.0314
Echinococcus granulosus smad 0.0041 0.0105 0.0177
Echinococcus granulosus voltage dependent calcium channel 0.0083 0.0268 0.0449
Echinococcus granulosus orexin receptor type 2 0.0295 0.1077 0.1804
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Loa Loa (eye worm) transcription factor SMAD2 0.06 0.2241 0.2236
Schistosoma mansoni biogenic amine receptor 0.0295 0.1077 0.1804
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0209 0.0746 0.125
Echinococcus granulosus TGF beta signal transducer SmadC 0.0041 0.0105 0.0177
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0018 0.0521
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0045 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.1345 0.5086 0.5083
Schistosoma mansoni nAChR subunit 0.006 0.018 0.0301
Echinococcus multilocularis potassium channel subfamily K 8 0.0045 0.0121 0.0182
Brugia malayi G-protein coupled receptor 0.0295 0.1077 0.1077
Echinococcus granulosus neuropeptide receptor 0.0295 0.1077 0.1804
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.003 0.003
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0015 0.0015
Treponema pallidum fructose-bisphosphate aldolase 0.0586 0.2186 1
Trypanosoma cruzi metacaspase, putative 0.0019 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.032 0.1171 0.1962
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0033 0.0073 0.0073
Echinococcus granulosus pyruvate kinase 0.0017 0.0016 0.0026
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0051 0.0145 0.0212
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Brugia malayi Pre-SET motif family protein 0.0439 0.1627 0.1627
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0051 0.0145 0.0212
Leishmania major hypothetical protein, conserved 0.0045 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Schistosoma mansoni twik family of potassium channels-related 0.0045 0.0121 0.0203
Loa Loa (eye worm) hypothetical protein 0.0161 0.0566 0.056
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0006 0.0006
Schistosoma mansoni ap endonuclease 0.0018 0.0019 0.0032
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0045 0.0123 0.0205
Schistosoma mansoni amine GPCR 0.0295 0.1077 0.1804
Schistosoma mansoni ran 0.0022 0.0031 0.0053
Schistosoma mansoni neurotransmitter gated ion channel 0.0033 0.0073 0.0123
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0295 0.1077 0.1613
Loa Loa (eye worm) hypothetical protein 0.0028 0.0056 0.0049
Loa Loa (eye worm) hypothetical protein 0.0028 0.0056 0.0049
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.003 0.003
Echinococcus granulosus peptidase Clp S14 family 0.0052 0.0148 0.0247
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Echinococcus granulosus neuropeptide receptor A26 0.0295 0.1077 0.1804
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0909 0.416
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0103 0.0342 0.1566
Loa Loa (eye worm) solute carrier family 6 member 4 0.0088 0.0286 0.028
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.0213 0.032
Echinococcus granulosus pyruvate kinase 0.0017 0.0016 0.0026
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0103 0.0342 0.1566
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.003 0.003
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0041 0.01
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0051 0.0145 0.0212
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0051 0.0145 0.0707
Loa Loa (eye worm) hypothetical protein 0.006 0.018 0.0173
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0051 0.0145 0.0707
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Loa Loa (eye worm) acetyltransferase 0.0145 0.0502 0.0496
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Schistosoma mansoni jumonji/arid domain-containing protein 0.0127 0.0435 0.0728
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0295 0.1077 0.1613
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0295 0.1077 0.1077
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Brugia malayi hypothetical protein 0.0028 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0 0.0001
Trypanosoma brucei metacaspase MCA3 0.0019 0.0023 0.0023
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0088 0.0286 0.0286
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0286 0.1042 0.1526
Schistosoma mansoni acetylcholine receptor-related 0.0028 0.0056 0.0093
Brugia malayi hypothetical protein 0.0295 0.1077 0.1077
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0673 0.2521 0.3777
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0078 0.0072
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0295 0.1077 0.1804
Loa Loa (eye worm) hypothetical protein 0.0052 0.0149 0.0143
Loa Loa (eye worm) CYP4Cod1 0.0088 0.0284 0.0278
Onchocerca volvulus 0.0045 0.0121 0.062
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0144 0.0144
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0034 0.0078 0.0115
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0112 0.2809
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Schistosoma mansoni neuropeptide F-like receptor 0.0295 0.1077 0.1804
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.0221 0.0323
Trypanosoma brucei metacaspase 5, putative 0.0019 0.0023 0.0023
Brugia malayi hypothetical protein 0.0295 0.1077 0.1077
Trypanosoma cruzi metacaspase, putative 0.0019 0.0023 0.0023
Brugia malayi hypothetical protein 0.0295 0.1077 0.1077
Echinococcus granulosus hypothetical protein 0.0295 0.1077 0.1804
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0103 0.0342 1
Schistosoma mansoni cytochrome P450 0.0051 0.0145 0.0243
Loa Loa (eye worm) hypothetical protein 0.006 0.018 0.0173
Echinococcus granulosus nAChR subunit 0.006 0.018 0.0301
Entamoeba histolytica Ran family GTPase 0.0022 0.0031 0.0056
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0112 0.3266
Echinococcus multilocularis lamin dm0 0.0113 0.0379 0.0568
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0221 0.037
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0295 0.1077 0.1613
Echinococcus granulosus neuropeptide s receptor 0.0295 0.1077 0.1804
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0066 0.0202 0.0339
Echinococcus granulosus mothers against decapentaplegic 5 0.0041 0.0105 0.0177
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0054 0.1584
Echinococcus multilocularis JmjC domain containing protein 4 0.0033 0.0075 0.0113
Schistosoma mansoni calcium-activated potassium channel 0.0878 0.3304 0.5534
Entamoeba histolytica hypothetical protein 0.0033 0.0073 0.025
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0144 0.0241
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0078 0.0389
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0051 0.0145 0.0212
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0144 0.0657
Loa Loa (eye worm) hypothetical protein 0.006 0.018 0.0173
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0023 0.0105
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.006 0.018 0.018
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0055 0.0159 0.3983
Onchocerca volvulus 0.0295 0.1077 0.5782
Mycobacterium ulcerans recombinase A 0.0109 0.0367 0.179
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.006 0.018 0.018
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0061 0.0061
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0016 0.0009 0.0014
Trypanosoma cruzi ion transport protein, putative 0.0045 0.0121 0.0121
Schistosoma mansoni sodium/chloride dependent transporter 0.0015 0.0008 0.0014
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0015 0.0006 0.001
Toxoplasma gondii pyruvate kinase PyK1 0.0034 0.0078 0.1969
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0109 0.0367 0.1382
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0909 0.416
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.0213 0.0213
Onchocerca volvulus 0.0295 0.1077 0.5782
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0041 0.02
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0019 0.0526
Giardia lamblia Pyruvate kinase 0.0034 0.0078 0.0359
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.006 0.018 0.0301
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0023 0.0105
Chlamydia trachomatis recombinase RecA 0.0109 0.0367 1
Echinococcus multilocularis glycine receptor subunit beta 0.006 0.018 0.0269
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0023 0.0105
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0031 0.0025
Echinococcus multilocularis fmrfamide receptor 0.0295 0.1077 0.1613
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0197 0.0703 0.0697
Echinococcus granulosus tm gpcr rhodopsin 0.0295 0.1077 0.1804
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0071 0.0221 0.0214
Echinococcus granulosus single minded 2 0.004 0.0103 0.0173
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0295 0.1077 0.1804
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.0157 0.0157
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0295 0.1077 0.1804
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0015 0.0378
Onchocerca volvulus 0.0129 0.0441 0.235
Loa Loa (eye worm) hypothetical protein 0.0028 0.0056 0.0049
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.006 0.018 0.0301
Schistosoma mansoni Smad4 0.0018 0.0019 0.0032
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0015 0.0015
Brugia malayi hypothetical protein 0.0028 0.0056 0.0056
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.003 0.003
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0613 0.2805
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.006 0.018 0.0173
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.003 0.003
Plasmodium falciparum importin beta, putative 0.0029 0.0061 0.1778
Schistosoma mansoni nAChR subunit 0.0028 0.0056 0.0093
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0045 0.0121 0.0182
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0079 0.0252 0.0422
Mycobacterium ulcerans hypothetical protein 0.0071 0.0221 0.1077
Schistosoma mansoni neuropeptide receptor 0.0295 0.1077 0.1804
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0051 0.0145 0.0707
Brugia malayi Cytochrome P450 family protein 0.0088 0.0284 0.0284
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0045 0.0121 0.0115
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0033 0.0073 0.0123
Loa Loa (eye worm) hypothetical protein 0.0071 0.0221 0.0214
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0008
Trypanosoma cruzi metacaspase 5, putative 0.0019 0.0023 0.0023
Trypanosoma cruzi DNA repair protein, putative 0.0034 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0033 0.0075 0.0069
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0015 0.044
Brugia malayi cytoplasmic intermediate filament protein 0.006 0.018 0.018
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0295 0.1077 0.1804
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0023 0.0105
Leishmania major DNA polymerase kappa, putative 0.0021 0.003 0.003
Trypanosoma brucei metacaspase 0.0019 0.0023 0.0023
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0221 0.0221
Leishmania major hypothetical protein, conserved 0.0045 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0024 0.0041 0.0035
Loa Loa (eye worm) acetylcholinesterase 1 0.0066 0.0202 0.0196
Loa Loa (eye worm) hypothetical protein 0.1576 0.5969 0.5967
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0579 0.2649
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0051 0.0142 0.0651
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0579 0.2649
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0136 0.047 0.0787
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0045 0.0121 0.0115
Leishmania major hypothetical protein, conserved 0.0027 0.0054 0.0054
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.0221 0.0323
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.004 0.0182
Schistosoma mansoni smad 0.0018 0.0019 0.0032
Brugia malayi hypothetical protein 0.002 0.0026 0.0026
Brugia malayi Cation transporter family protein 0.006 0.018 0.018
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.003 0.003
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0041 0.02
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0045 0.0121 0.0203
Schistosoma mansoni twik family of potassium channels-related 0.0045 0.0121 0.0203
Trypanosoma brucei Metacaspase-4 0.0019 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0161 0.0566 0.056
Giardia lamblia DNA repair protein RAD52 0.0359 0.1322 0.6046
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0045 0.0121 0.0182
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0006 0.0011
Brugia malayi hypothetical protein 0.0028 0.0056 0.0056
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0295 0.1077 0.1804
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0097 0.0321 0.1185
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0051 0.0145 0.0707
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.0221 0.0323
Giardia lamblia Hypothetical protein 0.0045 0.0121 0.0554
Trichomonas vaginalis conserved hypothetical protein 0.0013 0 0.0001
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0295 0.1077 0.1804
Onchocerca volvulus 0.0295 0.1077 0.5782
Trichomonas vaginalis glutaminase, putative 0.055 0.205 0.938
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0051 0.0145 0.0212
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0295 0.1077 0.1613
Echinococcus multilocularis lysine specific demethylase 5A 0.0124 0.0422 0.0632
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Echinococcus granulosus glycine receptor subunit alpha 1 0.006 0.018 0.0301
Trypanosoma brucei cytochrome P450, putative 0.0088 0.0284 0.0284
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0019 0.0088
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.003 0.005
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0051 0.0145 0.0707
Schistosoma mansoni cpg binding protein 0.0059 0.0174 0.0292
Onchocerca volvulus 0.0028 0.0056 0.0265
Loa Loa (eye worm) hypothetical protein 0.0034 0.0078 0.0072
Echinococcus multilocularis SAM and MBT domain containing protein 0.0052 0.0148 0.0222
Echinococcus granulosus small conductance calcium activated potassium 0.0978 0.3687 0.6177
Toxoplasma gondii ion channel protein 0.0045 0.0121 0.3044
Leishmania major protein kinase, putative 0.0019 0.0021 0.0021
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0095 0.031 0.052
Loa Loa (eye worm) hypothetical protein 0.0415 0.1536 0.153
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0095 0.031 0.031
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0023 0.0105
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.0221 0.1077
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0015 0.0022
Schistosoma mansoni neuropeptide receptor 0.0295 0.1077 0.1804
Brugia malayi glutathione reductase 0.0038 0.0096 0.0096
Brugia malayi CXXC zinc finger family protein 0.0059 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Schistosoma mansoni hypothetical protein 0.0017 0.0015 0.0025
Schistosoma mansoni inositol monophosphatase 0.0039 0.0097 0.0163
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0015 0.0006 0.0011
Loa Loa (eye worm) G-protein coupled receptor 0.0295 0.1077 0.1071
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0295 0.1077 0.1804
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0083 0.0268 0.0449
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0052 0.0148 0.0216
Brugia malayi Pyruvate kinase, muscle isozyme 0.0034 0.0078 0.0078
Brugia malayi MH2 domain containing protein 0.0041 0.0105 0.0105
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0083 0.0268 0.0449
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.0221 0.0323
Brugia malayi Doublecortin family protein 0.002 0.0026 0.0026
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0051 0.0145 0.0707
Loa Loa (eye worm) hypothetical protein 0.0463 0.1717 0.1712
Echinococcus granulosus sex peptide receptor 0.0295 0.1077 0.1804
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0059 0.0175 0.0175
Echinococcus granulosus neuropeptide receptor 0.0295 0.1077 0.1804
Schistosoma mansoni glutaminase 0.055 0.205 0.3435
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0023 0.0576
Trypanosoma brucei pyruvate kinase 1 0.0034 0.0078 0.0078
Echinococcus multilocularis peptidase Clp (S14 family) 0.0052 0.0148 0.0221
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0145 0.0502 0.0752
Schistosoma mansoni hypothetical protein 0.0045 0.0121 0.0203
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0064 0.0194 0.0291
Onchocerca volvulus 0.006 0.018 0.0936
Brugia malayi Tachykinin-like peptides receptor 99D 0.0295 0.1077 0.1077
Schistosoma mansoni voltage-gated cation channel 0.0083 0.0268 0.0449
Mycobacterium leprae Conserved hypothetical protein 0.0051 0.0145 0.0441
Onchocerca volvulus 0.0295 0.1077 0.5782
Onchocerca volvulus 0.0052 0.0148 0.0764
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0221 0.0221
Plasmodium falciparum potassium channel 0.0045 0.0121 0.3539
Plasmodium vivax hypothetical protein, conserved 0.0071 0.0221 0.6446
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Loa Loa (eye worm) hypothetical protein 0.0028 0.0056 0.0049
Mycobacterium leprae Probable lipase LipE 0.0071 0.0221 0.0762
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0286 0.1042 0.5081
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.1691 0.6407 0.9388
Onchocerca volvulus 0.0045 0.0121 0.062
Echinococcus multilocularis nAChR subunit 0.006 0.018 0.0269
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0194 0.0291
Echinococcus multilocularis smad 0.0041 0.0105 0.0158
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0026 0.0747
Schistosoma mansoni lipoxygenase 0.002 0.0026 0.0043
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0083 0.0268 0.0401
Echinococcus multilocularis g-protein coupled receptor 0.0295 0.1077 0.1613
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0144 0.0657
Loa Loa (eye worm) hypothetical protein 0.0029 0.0061 0.0054
Mycobacterium leprae Probable pyruvate kinase PykA 0.0034 0.0078 0.0158
Loa Loa (eye worm) hypothetical protein 0.0025 0.0044 0.0037
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Echinococcus multilocularis potassium channel subfamily K 8 0.0045 0.0121 0.0182
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0129 0.0441 0.0435
Loa Loa (eye worm) hypothetical protein 0.0088 0.0286 0.028
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0088 0.0286 0.048
Echinococcus granulosus intermediate filament protein 0.0113 0.0379 0.0635
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0051 0.0145 0.0212
Echinococcus granulosus serotonin transporter 0.0088 0.0286 0.048
Onchocerca volvulus 0.0036 0.0089 0.0444
Brugia malayi jmjC domain containing protein 0.0033 0.0075 0.0075
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.003 0.003
Echinococcus granulosus transcription factor Dp 1 0.004 0.0102 0.0171
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0023 0.0576
Brugia malayi Pre-SET motif family protein 0.0064 0.0194 0.0194
Entamoeba histolytica Flap nuclease, putative 0.0055 0.0159 0.0643
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0103 0.0342 1
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0028 0.0056 0.0093
Loa Loa (eye worm) hypothetical protein 0.1576 0.5969 0.5967
Loa Loa (eye worm) hypothetical protein 0.0028 0.0056 0.0049
Onchocerca volvulus 0.042 0.1553 0.8354
Onchocerca volvulus 0.0295 0.1077 0.5782
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0033 0.0073 0.0073
Brugia malayi Inositol-1 0.0039 0.0097 0.0097
Schistosoma mansoni hypothetical protein 0.0017 0.0015 0.0025
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0019 0.0088
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0586 0.2186 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0295 0.1077 0.1613
Echinococcus multilocularis RUN 0.002 0.0026 0.0038
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0051 0.0145 0.0707
Schistosoma mansoni smad 0.0041 0.0105 0.0177
Onchocerca volvulus 0.05 0.1858 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0673 0.2521 0.4224
Trypanosoma cruzi C-8 sterol isomerase, putative 0.2631 1 1
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0031 0.0069 0.0069
Toxoplasma gondii cytochrome p450 superfamily protein 0.0051 0.0145 0.3642
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0054 0.0054
Treponema pallidum sodium- and chloride- dependent transporter 0.0088 0.0286 0.131
Brugia malayi hypothetical protein 0.002 0.0026 0.0026
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.0221 0.0323
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0103 0.0342 0.1566
Echinococcus granulosus lamin dm0 0.0113 0.0379 0.0635
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0194 0.0325
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0051 0.0145 0.0212
Onchocerca volvulus 0.0295 0.1077 0.5782
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0579 0.2649
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.003 0.003
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0197 0.0703 0.1178
Brugia malayi neuropeptide F receptor 0.0295 0.1077 0.1077
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0586 0.2186 1
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0055 0.0159 0.0159
Loa Loa (eye worm) hypothetical protein 0.006 0.018 0.0173
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0051 0.0145 0.0707
Plasmodium falciparum JmjC domain-containing protein, putative 0.0033 0.0075 0.2199
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0095 0.031 0.031
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0026 0.0043
Schistosoma mansoni twik family of potassium channels-related 0.0045 0.0121 0.0203
Schistosoma mansoni hypothetical protein 0.0295 0.1077 0.1804
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0112 0.0187
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0028 0.0056 0.0083
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0083 0.0268 0.0401
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.003 0.005
Mycobacterium tuberculosis Probable reductase 0.0087 0.0283 0.0415
Echinococcus granulosus sodium and chloride dependent glycine 0.0015 0.0006 0.0011
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.006 0.018 0.018
Onchocerca volvulus 0.0295 0.1077 0.5782
Loa Loa (eye worm) voltage-dependent calcium channel 0.0031 0.0067 0.0061
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0098 0.0147
Brugia malayi hypothetical protein 0.0295 0.1077 0.1077
Echinococcus granulosus polycomb protein SCMH1 0.0052 0.0148 0.0248
Schistosoma mansoni biogenic amine receptor 0.0295 0.1077 0.1804
Echinococcus multilocularis rhodopsin orphan GPCR 0.0295 0.1077 0.1613
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0015 0.0025
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0295 0.1077 0.1804
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0083 0.0268 0.0268
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Schistosoma mansoni hypothetical protein 0.0295 0.1077 0.1804
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.0213 0.0207
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0586 0.2186 1
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0045 0.0121 0.0121
Brugia malayi hypothetical protein 0.0028 0.0056 0.0056
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0295 0.1077 0.1804
Giardia lamblia DINP protein human, muc B family 0.0021 0.003 0.0136
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0041 0.02
Schistosoma mansoni lamin 0.0113 0.0379 0.0635
Brugia malayi jmjC domain containing protein 0.0033 0.0075 0.0075
Echinococcus granulosus flap endonuclease 1 0.0055 0.0159 0.0266
Schistosoma mansoni acetylcholine receptor subunit beta 0.0028 0.0056 0.0093
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.006 0.018 0.0301
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0251 0.0909 0.0909
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0028 0.0056 0.0056
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.047 0.0787
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0 0.0001
Echinococcus multilocularis voltage dependent calcium channel 0.0083 0.0268 0.0401
Leishmania major cytochrome p450-like protein 0.0088 0.0284 0.0284
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0051 0.0145 0.0707
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0015 0.0006 0.0011
Brugia malayi beta-lactamase family protein 0.0071 0.0221 0.0221
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0097 0.0321 0.047
Echinococcus granulosus neuropeptide Y receptor 0.0295 0.1077 0.1804
Echinococcus multilocularis voltage dependent calcium channel 0.0083 0.0268 0.0401
Echinococcus granulosus tachykinin peptides receptor 99D 0.0295 0.1077 0.1804
Brugia malayi larval opioid receptor 0.0295 0.1077 0.1077
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0015 0.0006 0.0006
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0045 0.0121 0.0115
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.003 0.003
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0019 0.0028
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0039 0.0033
Entamoeba histolytica hypothetical protein 0.0039 0.0098 0.0362
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0033 0.0073 0.0073
Brugia malayi jmjC domain containing protein 0.0124 0.0422 0.0422
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0018 0.0026
Loa Loa (eye worm) hypothetical protein 0.0088 0.0286 0.028
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0295 0.1077 0.1804
Brugia malayi hypothetical protein 0.033 0.1208 0.1208
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0014 0.0021
Brugia malayi sulfakinin receptor protein 0.0295 0.1077 0.1077
Echinococcus multilocularis flap endonuclease 1 0.0055 0.0159 0.0237
Loa Loa (eye worm) TYRA-2 protein 0.0295 0.1077 0.1071
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0209 0.0746 0.1118
Loa Loa (eye worm) neuropeptide F receptor 0.0295 0.1077 0.1071
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Toxoplasma gondii hypothetical protein 0.0025 0.0044 0.1096
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0097 0.2643
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0098 0.0164
Echinococcus multilocularis muscleblind protein 1 0.0161 0.0566 0.0848
Loa Loa (eye worm) cytochrome P450 0.0051 0.0145 0.0139
Loa Loa (eye worm) serotonin transporter b 0.0088 0.0286 0.028
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0295 0.1077 0.1804
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0015 0.0006 0.001
Schistosoma mansoni ran 0.0022 0.0031 0.0053
Echinococcus granulosus apoptotic protease activating factor 1 0.0079 0.025 0.0418
Echinococcus granulosus pyruvate kinase 0.0017 0.0016 0.0026
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0045 0.0121 0.0121
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0295 0.1077 0.1804
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0015 0.0025
Toxoplasma gondii thioredoxin reductase 0.0038 0.0096 0.2404
Loa Loa (eye worm) hypothetical protein 0.0295 0.1077 0.1071
Loa Loa (eye worm) norepinephrine transporter 0.0088 0.0286 0.028
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0078 0.0389
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0045 0.0121 0.0121
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0054 0.0157 0.0235
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0014 0.0021
Echinococcus granulosus acetylcholinesterase 0.0066 0.0202 0.0339

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 1.51 uM Antiproliferative activity against human Bel7402 cells assessed as growth inhibition by MTT assay ChEMBL. 23274570

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 23274570

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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