Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0376 | 0.1455 | 0.1453 |
Loa Loa (eye worm) | hypothetical protein | 0.0831 | 0.3409 | 1 |
Brugia malayi | hypothetical protein | 0.0831 | 0.3409 | 1 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0192 | 0.0667 | 0.0665 |
Schistosoma mansoni | hypothetical protein | 0.0396 | 0.154 | 0.1539 |
Loa Loa (eye worm) | hypothetical protein | 0.0831 | 0.3409 | 1 |
Onchocerca volvulus | 0.0831 | 0.3409 | 1 | |
Onchocerca volvulus | 0.0831 | 0.3409 | 1 | |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0396 | 0.154 | 0.1539 |
Brugia malayi | Animal haem peroxidase family protein | 0.0831 | 0.3409 | 1 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0192 | 0.0667 | 0.0665 |
Onchocerca volvulus | Peroxidasin homolog | 0.0831 | 0.3409 | 1 |
Onchocerca volvulus | 0.0396 | 0.154 | 0.4501 | |
Brugia malayi | Animal haem peroxidase family protein | 0.0831 | 0.3409 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0831 | 0.3409 | 1 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0396 | 0.154 | 0.1539 |
Onchocerca volvulus | Peroxidase homolog | 0.0831 | 0.3409 | 1 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0396 | 0.154 | 0.5 |
Brugia malayi | hypothetical protein | 0.0192 | 0.0667 | 0.1956 |
Loa Loa (eye worm) | hypothetical protein | 0.0831 | 0.3409 | 1 |
Onchocerca volvulus | 0.0831 | 0.3409 | 1 | |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0831 | 0.3409 | 1 |
Schistosoma mansoni | lipoxygenase | 0.1654 | 0.6943 | 0.6943 |
Onchocerca volvulus | Dual oxidase homolog | 0.0831 | 0.3409 | 1 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0396 | 0.154 | 0.1539 |
Echinococcus granulosus | RUN | 0.0396 | 0.154 | 0.1539 |
Onchocerca volvulus | 0.0396 | 0.154 | 0.4501 | |
Loa Loa (eye worm) | hypothetical protein | 0.0396 | 0.154 | 0.4518 |
Brugia malayi | Blistered cuticle protein 3 | 0.0831 | 0.3409 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0831 | 0.3409 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0831 | 0.3409 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0831 | 0.3409 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0831 | 0.3409 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0192 | 0.0667 | 0.1956 |
Echinococcus granulosus | neuropeptide s receptor | 0.0376 | 0.1455 | 0.1453 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0831 | 0.3409 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0037 | 0.0002 | 0.0005 |
Brugia malayi | Doublecortin family protein | 0.0396 | 0.154 | 0.4518 |
Loa Loa (eye worm) | doublecortin family protein | 0.0396 | 0.154 | 0.4518 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0037 | 0.0002 | 0.0005 |
Schistosoma mansoni | loxhd1 | 0.0396 | 0.154 | 0.1539 |
Schistosoma mansoni | rab6-interacting | 0.0396 | 0.154 | 0.1539 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0396 | 0.154 | 0.1539 |
Loa Loa (eye worm) | hypothetical protein | 0.0831 | 0.3409 | 1 |
Schistosoma mansoni | lipoxygenase | 0.2367 | 1 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0831 | 0.3409 | 1 |
Schistosoma mansoni | polycystin 1-related | 0.0396 | 0.154 | 0.1539 |
Schistosoma mansoni | survival motor neuron protein | 0.0039 | 0.001 | 0.0009 |
Schistosoma mansoni | peroxidasin | 0.0831 | 0.3409 | 0.3408 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0376 | 0.1455 | 0.1453 |
Echinococcus multilocularis | peroxidasin | 0.0831 | 0.3409 | 0.3408 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0831 | 0.3409 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0831 | 0.3409 | 1 |
Brugia malayi | hypothetical protein | 0.0396 | 0.154 | 0.4518 |
Loa Loa (eye worm) | hypothetical protein | 0.0831 | 0.3409 | 1 |
Echinococcus multilocularis | RUN | 0.0396 | 0.154 | 0.1539 |
Brugia malayi | hypothetical protein | 0.0396 | 0.154 | 0.4518 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0396 | 0.154 | 0.1539 |
Brugia malayi | Animal haem peroxidase family protein | 0.0831 | 0.3409 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0831 | 0.3409 | 1 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.2367 | 1 | 1 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0039 | 0.001 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0831 | 0.3409 | 1 |
Echinococcus granulosus | peroxidasin | 0.0831 | 0.3409 | 0.3408 |
Loa Loa (eye worm) | hypothetical protein | 0.0831 | 0.3409 | 1 |
Brugia malayi | Peroxidasin | 0.0831 | 0.3409 | 1 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0396 | 0.154 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0396 | 0.154 | 0.4518 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0376 | 0.1455 | 0.1453 |
Schistosoma mansoni | peroxidasin | 0.0831 | 0.3409 | 0.3408 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0396 | 0.154 | 0.1539 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.001 | 0.0009 |
Onchocerca volvulus | Peroxidasin homolog | 0.0831 | 0.3409 | 1 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0831 | 0.3409 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0831 | 0.3409 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0831 | 0.3409 | 1 |
Schistosoma mansoni | rab6-interacting | 0.0396 | 0.154 | 0.1539 |
Loa Loa (eye worm) | hypothetical protein | 0.0831 | 0.3409 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0831 | 0.3409 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.