Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.2997 | 0.2997 |
Loa Loa (eye worm) | RNA binding protein | 0.0069 | 0.2997 | 0.3454 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.2997 | 0.2997 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.2997 | 0.2997 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0019 | 0 | 0.5 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0069 | 0.2997 | 0.3454 |
Brugia malayi | RNA binding protein | 0.0069 | 0.2997 | 0.3454 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.2997 | 0.2997 |
Echinococcus granulosus | tar DNA binding protein | 0.0069 | 0.2997 | 0.2997 |
Schistosoma mansoni | hypothetical protein | 0.0183 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0069 | 0.2997 | 0.3454 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.2997 | 0.2997 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Loa Loa (eye worm) | TAR-binding protein | 0.0069 | 0.2997 | 0.3454 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Echinococcus multilocularis | tar DNA binding protein | 0.0069 | 0.2997 | 0.2997 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0129 | 0.6696 | 0.7718 |
Schistosoma mansoni | hypothetical protein | 0.0183 | 1 | 1 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0129 | 0.6696 | 0.7718 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0019 | 0 | 0.5 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Brugia malayi | MH2 domain containing protein | 0.0129 | 0.6696 | 0.7718 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0162 | 0.8675 | 0.8675 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Brugia malayi | TAR-binding protein | 0.0069 | 0.2997 | 0.3454 |
Brugia malayi | Muscleblind-like protein | 0.0162 | 0.8675 | 1 |
Echinococcus granulosus | muscleblind protein | 0.0162 | 0.8675 | 0.8675 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.8675 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.8675 | 1 |
Echinococcus multilocularis | muscleblind protein | 0.0162 | 0.8675 | 0.8675 |
Echinococcus multilocularis | geminin | 0.0183 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (ADMET) | Inhibition of COX-2 (unknown origin) at 5 uM | ChEMBL. | 23237838 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.