Detailed information for compound 1741257

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 422.52 | Formula: C24H30N4O3
  • H donors: 2 H acceptors: 3 LogP: 4.33 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(N(C(C(=O)NC(C)(C)C)c1cn[nH]c1)c1ccc(cc1)C(C)(C)C)c1ccco1
  • InChi: 1S/C24H30N4O3/c1-23(2,3)17-9-11-18(12-10-17)28(22(30)19-8-7-13-31-19)20(16-14-25-26-15-16)21(29)27-24(4,5)6/h7-15,20H,1-6H3,(H,25,26)(H,27,29)
  • InChiKey: LOMABGWEWYUDCZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0036 0.2503 0.2503
Onchocerca volvulus 0.0108 1 0.5
Schistosoma mansoni myosin xvIII 0.0108 1 1
Echinococcus granulosus fmrfamide receptor 0.0108 1 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0108 1 1
Onchocerca volvulus 0.0108 1 0.5
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0108 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 1 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0108 1 1
Schistosoma mansoni neuropeptide F-like receptor 0.0108 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0108 1 1
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.002 0.0791 0.5
Schistosoma mansoni neuropeptide F-like receptor 0.0108 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Loa Loa (eye worm) G-protein coupled receptor 0.0108 1 1
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0042 0.3074 0.3074
Echinococcus granulosus alpha 1A adrenergic receptor 0.0108 1 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Echinococcus multilocularis neuropeptide receptor A26 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Schistosoma mansoni opsin-like receptor 0.0108 1 1
Brugia malayi putative neuropeptide receptor NPR1 0.0108 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 1 1
Schistosoma mansoni amine GPCR 0.0108 1 1
Echinococcus granulosus neuropeptide receptor 0.0108 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 1 1
Brugia malayi Cytochrome P450 family protein 0.0059 0.4856 0.4856
Echinococcus granulosus g protein coupled receptor 0.0108 1 1
Schistosoma mansoni histamine h1 receptor 0.0108 1 1
Echinococcus granulosus neuropeptide Y receptor 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.2789 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 1 1
Trypanosoma brucei cytochrome P450, putative 0.0059 0.4856 1
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.002 0.0791 0.5
Echinococcus granulosus allatostatin A receptor 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Echinococcus granulosus tm gpcr rhodopsin 0.0108 1 1
Onchocerca volvulus 0.0108 1 0.5
Schistosoma mansoni amine GPCR 0.0108 1 1
Loa Loa (eye worm) CYP4Cod1 0.0059 0.4856 0.4856
Onchocerca volvulus 0.0108 1 0.5
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0108 1 1
Echinococcus multilocularis g-protein coupled receptor 0.0108 1 1
Brugia malayi Cytochrome P450 family protein 0.0059 0.4856 0.4856
Schistosoma mansoni neuropeptide receptor 0.0108 1 1
Brugia malayi hypothetical protein 0.0108 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 1 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0108 1 1
Onchocerca volvulus 0.0108 1 0.5
Mycobacterium leprae Conserved hypothetical protein 0.002 0.0791 0.5
Onchocerca volvulus 0.0108 1 0.5
Echinococcus granulosus neuropeptide s receptor 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Echinococcus multilocularis dro:myosuppressin receptor 0.0108 1 1
Echinococcus granulosus hypothetical protein 0.0108 1 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0108 1 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0108 1 1
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0108 1 1
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.002 0.0791 0.5
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0108 1 1
Trypanosoma cruzi cytochrome P450, putative 0.0059 0.4856 1
Schistosoma mansoni neuropeptide receptor 0.0108 1 1
Echinococcus multilocularis neuropeptide Y receptor 0.0108 1 1
Brugia malayi hypothetical protein 0.0108 1 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0059 0.4856 0.4856
Schistosoma mansoni biogenic amine receptor 0.0108 1 1
Schistosoma mansoni opsin-like receptor 0.0108 1 1
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.002 0.0791 0.5
Onchocerca volvulus 0.0108 1 0.5
Echinococcus multilocularis fmrfamide receptor 0.0108 1 1
Onchocerca volvulus 0.0108 1 0.5
Echinococcus multilocularis neuropeptide receptor 0.0108 1 1
Brugia malayi Dopamine receptor 0.0108 1 1
Echinococcus multilocularis neuropeptide receptor 0.0108 1 1
Echinococcus granulosus neuropeptide receptor 0.0108 1 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0108 1 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0108 1 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Brugia malayi follicle stimulating hormone receptor 0.0108 1 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.0108 1 1
Brugia malayi hypothetical protein 0.0108 1 1
Schistosoma mansoni hypothetical protein 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0108 1 1
Schistosoma mansoni hypothetical protein 0.0108 1 1
Brugia malayi RE15519p 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Echinococcus multilocularis neuropeptide s receptor 0.0108 1 1
Brugia malayi AKH receptor 0.0108 1 1
Onchocerca volvulus 0.0108 1 0.5
Brugia malayi neuropeptide F receptor 0.0108 1 1
Schistosoma mansoni biogenic amine receptor 0.0108 1 1
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.002 0.0791 0.5
Brugia malayi putative neuropeptide receptor 0.0108 1 1
Brugia malayi G-protein coupled receptor 0.0108 1 1
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.002 0.0791 0.5
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0108 1 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0108 1 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0108 1 1
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.002 0.0791 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 1 1
Echinococcus multilocularis sex peptide receptor 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0042 0.3074 0.3074
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0108 1 1
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.002 0.0791 0.5
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Echinococcus multilocularis somatostatin receptor 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0108 1 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0108 1 1
Echinococcus granulosus 7tm_1 domain containing protein 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Echinococcus multilocularis 0.002 0.0791 0.0791
Onchocerca volvulus Neuropeptide F receptor homolog 0.0108 1 0.5
Echinococcus multilocularis g protein coupled receptor 0.0108 1 1
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.002 0.0791 0.5
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0108 1 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0108 1 1
Schistosoma mansoni hypothetical protein 0.0108 1 1
Brugia malayi G protein-coupled receptor 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0108 1 1
Brugia malayi hypothetical protein 0.0108 1 1
Brugia malayi G-protein coupled receptor 0.0108 1 1
Leishmania major cytochrome p450-like protein 0.0059 0.4856 1
Loa Loa (eye worm) TYRA-2 protein 0.0108 1 1
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.3472 0.3472
Echinococcus granulosus 7TM GPCR rhodopsin 0.0108 1 1
Loa Loa (eye worm) neuropeptide F receptor 0.0108 1 1
Echinococcus granulosus tm gpcr rhodopsin 0.0108 1 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0108 1 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0108 1 1
Brugia malayi sulfakinin receptor protein 0.0108 1 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0108 1 1
Schistosoma mansoni biogenic amine receptor 0.0108 1 1
Echinococcus multilocularis neuropeptides capa receptor 0.0108 1 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0108 1 1
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0791 0.0791
Brugia malayi ORL1-like opioid receptor 0.0108 1 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0108 1 1
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.002 0.0791 0.5
Echinococcus multilocularis G protein coupled receptor 139 0.0108 1 1
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.002 0.0791 0.5
Echinococcus granulosus tachykinin peptides receptor 99D 0.0108 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 1 1
Mycobacterium leprae putative cytochrome p450 0.002 0.0791 0.5
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0108 1 1
Echinococcus multilocularis g protein coupled receptor 0.0108 1 1
Loa Loa (eye worm) neuropeptide F receptor 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 1 1
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.002 0.0791 0.5
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0108 1 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Schistosoma mansoni amine GPCR 0.0108 1 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0108 1 1
Onchocerca volvulus 0.0108 1 0.5
Echinococcus granulosus g protein coupled receptor 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0108 1 1
Echinococcus granulosus sex peptide receptor 0.0108 1 1
Schistosoma mansoni hypothetical protein 0.002 0.0791 0.0791
Loa Loa (eye worm) cytochrome P450 0.002 0.0791 0.0791
Echinococcus granulosus neuropeptide receptor A26 0.0108 1 1
Echinococcus granulosus G protein coupled receptor 139 0.0108 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 1 1
Brugia malayi hypothetical protein 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Echinococcus granulosus cytochrome P450 2K1 0.002 0.0791 0.0791
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Echinococcus multilocularis serotonin receptor 0.0108 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 1 1
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.002 0.0791 0.5
Echinococcus granulosus neuropeptides capa receptor 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.2811 0.2811
Brugia malayi Serotonin receptor 0.0108 1 1
Trypanosoma cruzi cytochrome P450, putative 0.0059 0.4856 1
Schistosoma mansoni adenoreceptor 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.002 0.0791 0.5
Brugia malayi G protein-coupled receptor F59B2.13 0.0108 1 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0108 1 1
Brugia malayi hypothetical protein 0.0108 1 1
Schistosoma mansoni cytochrome P450 0.002 0.0791 0.0791
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Onchocerca volvulus 0.0108 1 0.5
Brugia malayi Serotonin receptor 0.0108 1 1
Schistosoma mansoni amine GPCR 0.0108 1 1
Echinococcus granulosus neuropeptides capa receptor 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0042 0.3074 0.3074
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.2789 0.5
Schistosoma mansoni neuropeptide receptor 0.0108 1 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0108 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 1 1
Onchocerca volvulus 0.0108 1 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.0108 1 1
Echinococcus granulosus tm gpcr rhodopsin 0.0108 1 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0108 1 1
Echinococcus granulosus neuropeptide Y receptor 0.0108 1 1
Brugia malayi hypothetical protein 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Echinococcus multilocularis neuropeptide Y receptor 0.0108 1 1
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.002 0.0791 0.5
Echinococcus multilocularis orexin receptor type 2 0.0108 1 1
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.002 0.0791 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 1 1
Echinococcus multilocularis serotonin receptor 0.0108 1 1
Schistosoma mansoni opsin-like receptor 0.0108 1 1
Echinococcus multilocularis g protein coupled receptor 0.0108 1 1
Onchocerca volvulus 0.0108 1 0.5
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Onchocerca volvulus 0.0108 1 0.5
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Brugia malayi GnHR receptor homolog 0.0108 1 1
Brugia malayi Dopamine receptor protein 1 0.0108 1 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0108 1 1
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.3472 0.3472
Loa Loa (eye worm) cytochrome P450 family protein 0.0059 0.4856 0.4856
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 1 1
Echinococcus multilocularis neuropeptides capa receptor 0.0108 1 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0108 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0108 1 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0108 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 1 1
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.002 0.0791 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 1 1
Onchocerca volvulus 0.0108 1 0.5
Brugia malayi neuropeptide F receptor 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Echinococcus granulosus orexin receptor type 2 0.0108 1 1
Toxoplasma gondii cytochrome p450 superfamily protein 0.002 0.0791 0.5
Brugia malayi hypothetical protein 0.0108 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Onchocerca volvulus 0.0108 1 0.5
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.002 0.0791 0.5
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.002 0.0791 0.5
Schistosoma mansoni alpha-1 adrenergic receptor 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0108 1 1
Echinococcus multilocularis G-protein coupled receptor, putative 0.0108 1 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0108 1 1
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0059 0.4856 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.002 0.0791 0.5
Echinococcus granulosus serotonin receptor 0.0108 1 1
Echinococcus granulosus g protein coupled receptor 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0108 1 1
Brugia malayi larval opioid receptor 0.0108 1 1
Loa Loa (eye worm) G-protein coupled receptor 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Brugia malayi Melatonin receptor type 1A 0.0108 1 1
Schistosoma mansoni amine GPCR 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 1 1
Schistosoma mansoni neuropeptide receptor 0.0108 1 1
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0108 1 1
Brugia malayi Dopamine receptor protein 2 0.0108 1 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0108 1 1
Echinococcus multilocularis allatostatin A receptor 0.0108 1 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0108 1 1
Brugia malayi cytochrome P450 0.002 0.0791 0.0791
Echinococcus granulosus biogenic amine 5HT receptor 0.0108 1 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0108 1 0.5
Brugia malayi Cytochrome P450 family protein 0.002 0.0791 0.0791
Onchocerca volvulus 0.0108 1 0.5
Echinococcus granulosus dro:myosuppressin receptor 0.0108 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 1 1
Brugia malayi Cytochrome P450 family protein 0.002 0.0791 0.0791
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0108 1 1
Schistosoma mansoni hypothetical protein 0.0108 1 1
Echinococcus granulosus somatostatin receptor 0.0108 1 1
Echinococcus multilocularis fmrfamide receptor 0.0108 1 1
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0042 0.3074 0.3074
Echinococcus granulosus g-protein coupled receptor 0.0108 1 1
Brugia malayi hypothetical protein 0.0108 1 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0108 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 1 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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