Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.1284 | 0.1802 | 0.2694 |
Echinococcus multilocularis | type II inositol 3,4 bisphosphate 4 phosphatase | 0.0183 | 0.0129 | 0.0193 |
Leishmania major | protein kinase, putative | 0.0231 | 0.0202 | 1 |
Echinococcus granulosus | oxysterol binding protein 3 | 0.0183 | 0.0129 | 0.0193 |
Schistosoma mansoni | atypical protein kinase C | 0.2225 | 0.3234 | 0.4833 |
Echinococcus multilocularis | arf GAP with SH3 domain, ANK repeat and PH | 0.0183 | 0.0129 | 0.0193 |
Leishmania major | protein kinase, putative | 0.0231 | 0.0202 | 1 |
Schistosoma mansoni | rho gtpase activating protein | 0.0183 | 0.0129 | 0.0193 |
Echinococcus granulosus | myotubularin protein 13 | 0.0183 | 0.0129 | 0.0193 |
Leishmania major | serine/threonine-protein kinase a, putative | 0.0231 | 0.0202 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Trichomonas vaginalis | AGC family protein kinase | 0.0231 | 0.0202 | 0.0074 |
Entamoeba histolytica | hypothetical protein, conserved domain containing | 0.0183 | 0.0129 | 0.0129 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Entamoeba histolytica | protein kinase, putative | 0.0231 | 0.0202 | 0.0202 |
Trichomonas vaginalis | AGC family protein kinase | 0.6676 | 1 | 1 |
Echinococcus granulosus | pleckstrin y domain containing family A | 0.0183 | 0.0129 | 0.0193 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.2225 | 0.3234 | 0.3234 |
Loa Loa (eye worm) | uncoordinated protein 104 | 0.0183 | 0.0129 | 0.0129 |
Echinococcus granulosus | arf GAP with SH3 domain ANK repeat and PH | 0.0183 | 0.0129 | 0.0193 |
Echinococcus granulosus | Pleckstrin y | 0.0183 | 0.0129 | 0.0193 |
Onchocerca volvulus | Protein melted homolog | 0.0183 | 0.0129 | 1 |
Trypanosoma cruzi | Serine/threonine-protein kinase NEK21, putative | 0.0231 | 0.0202 | 0.0302 |
Brugia malayi | Dynamin | 0.0183 | 0.0129 | 0.0129 |
Loa Loa (eye worm) | Plekhf2 protein | 0.0183 | 0.0129 | 0.0129 |
Echinococcus granulosus | nervana 2 | 0.4268 | 0.6339 | 0.9475 |
Trichomonas vaginalis | AGC family protein kinase | 0.0231 | 0.0202 | 0.0074 |
Echinococcus granulosus | DCC interacting protein 13 beta | 0.0183 | 0.0129 | 0.0193 |
Loa Loa (eye worm) | metabotropic GABA-B receptor subtype 2 | 0.0267 | 0.0257 | 0.0257 |
Echinococcus granulosus | Pleckstrin domain containing protein family B | 0.0183 | 0.0129 | 0.0193 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.1186 | 0.1653 | 0.2471 |
Trichomonas vaginalis | AGC family protein kinase | 0.0231 | 0.0202 | 0.0074 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0874 | 0.1179 | 0.1762 |
Echinococcus granulosus | Rho GTPase activating protein 24 | 0.0183 | 0.0129 | 0.0193 |
Toxoplasma gondii | protein kinase domain-containing protein | 0.0231 | 0.0202 | 0.0076 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.2225 | 0.3234 | 0.4833 |
Entamoeba histolytica | hypothetical protein, conserved domain containing | 0.0183 | 0.0129 | 0.0129 |
Echinococcus granulosus | GPCR family 3 C terminal | 0.0169 | 0.0108 | 0.0162 |
Schistosoma mansoni | goodpasture antigen-binding protein | 0.0183 | 0.0129 | 0.0193 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.4499 | 0.669 | 1 |
Schistosoma mansoni | guanyl-nucleotide exchange factor | 0.0183 | 0.0129 | 0.0193 |
Entamoeba histolytica | Rho guanine nucleotide exchange factor, putative | 0.0183 | 0.0129 | 0.0129 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.4499 | 0.669 | 0.669 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Entamoeba histolytica | hypothetical protein, conserved domain containing | 0.0183 | 0.0129 | 0.0129 |
Loa Loa (eye worm) | receptor family ligand binding region containing protein | 0.0267 | 0.0257 | 0.0257 |
Schistosoma mansoni | serine/threonine protein kinase | 0.2225 | 0.3234 | 0.4833 |
Entamoeba histolytica | Rho guanine nucleotide exchange factor, putative | 0.0183 | 0.0129 | 0.0129 |
Brugia malayi | Protein kinase domain containing protein | 0.2225 | 0.3234 | 0.3234 |
Brugia malayi | GTP-ase activating protein for Arf containing protein | 0.0183 | 0.0129 | 0.0129 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Brugia malayi | PH domain containing protein | 0.0183 | 0.0129 | 0.0129 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.2225 | 0.3234 | 0.3234 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Trypanosoma cruzi | PH domain containing protein, putative | 0.0183 | 0.0129 | 0.0193 |
Brugia malayi | probable spectrin beta chain | 0.0183 | 0.0129 | 0.0129 |
Schistosoma mansoni | serine/threonine kinase | 0.2225 | 0.3234 | 0.4833 |
Onchocerca volvulus | 0.0183 | 0.0129 | 1 | |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0231 | 0.0202 | 0.0202 |
Trichomonas vaginalis | AGC family protein kinase | 0.6676 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Echinococcus granulosus | FERM and pleckstrin domain containing protein | 0.0183 | 0.0129 | 0.0193 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.2225 | 0.3234 | 0.4833 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.2225 | 0.3234 | 0.4833 |
Trichomonas vaginalis | AGC family protein kinase | 0.0231 | 0.0202 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Entamoeba histolytica | hypothetical protein | 0.0231 | 0.0202 | 0.0202 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0183 | 0.0129 | 0.0129 |
Echinococcus granulosus | GRB2 associated binding protein 3 | 0.0183 | 0.0129 | 0.0193 |
Brugia malayi | PH domain containing protein | 0.0183 | 0.0129 | 0.0129 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Brugia malayi | MAX-1A | 0.0183 | 0.0129 | 0.0129 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.4316 | 0.6412 | 0.9584 |
Brugia malayi | Dynamin | 0.0183 | 0.0129 | 0.0129 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0231 | 0.0202 | 0.0302 |
Entamoeba histolytica | PH domain containing protein | 0.0183 | 0.0129 | 0.0129 |
Brugia malayi | TBC domain containing protein | 0.0183 | 0.0129 | 0.0129 |
Leishmania major | rac serine-threonine kinase, putative,protein kinase, putative | 0.0231 | 0.0202 | 1 |
Plasmodium falciparum | calcium-dependent protein kinase 7 | 0.0231 | 0.0202 | 0.0116 |
Echinococcus multilocularis | nervana 2 | 0.4268 | 0.6339 | 0.9475 |
Entamoeba histolytica | Rho guanine nucleotide exchange factor, putative | 0.0183 | 0.0129 | 0.0129 |
Brugia malayi | Variant SH3 domain containing protein | 0.0183 | 0.0129 | 0.0129 |
Echinococcus multilocularis | GPCR, family 3, C terminal | 0.0169 | 0.0108 | 0.0162 |
Trichomonas vaginalis | AGC family protein kinase | 0.0231 | 0.0202 | 0.0074 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.2225 | 0.3234 | 0.3234 |
Schistosoma mansoni | syntrophin | 0.0183 | 0.0129 | 0.0193 |
Brugia malayi | Receptor family ligand binding region containing protein | 0.0267 | 0.0257 | 0.0257 |
Trypanosoma cruzi | hypothetical protein | 0.0183 | 0.0129 | 0.0193 |
Schistosoma mansoni | hypothetical protein | 0.0183 | 0.0129 | 0.0193 |
Brugia malayi | GTPase-activator protein for Ras-like GTPase containing protein | 0.0183 | 0.0129 | 0.0129 |
Trypanosoma cruzi | NEK family Serine/threonine-protein kinase, putative | 0.0231 | 0.0202 | 0.0302 |
Trichomonas vaginalis | AGC family protein kinase | 0.6676 | 1 | 1 |
Echinococcus granulosus | oxysterol binding protein 9 | 0.0183 | 0.0129 | 0.0193 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0945 | 0.1287 | 0.1287 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.2225 | 0.3234 | 0.4833 |
Entamoeba histolytica | protein kinase, putative | 0.6676 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Schistosoma mansoni | vav2 | 0.0183 | 0.0129 | 0.0193 |
Entamoeba histolytica | protein kinase, putative | 0.6676 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Loa Loa (eye worm) | GTP-ase activating protein for Arf containing protein | 0.0183 | 0.0129 | 0.0129 |
Trypanosoma cruzi | hypothetical protein | 0.0183 | 0.0129 | 0.0193 |
Trichomonas vaginalis | AGC family protein kinase | 0.0231 | 0.0202 | 0.0074 |
Echinococcus multilocularis | Ras associated and pleckstrin y | 0.0183 | 0.0129 | 0.0193 |
Echinococcus granulosus | protein kinase c iota type | 0.2225 | 0.3234 | 0.4833 |
Trichomonas vaginalis | ribosomal protein S6 kinase, 90kD, polypeptide, putative | 0.0231 | 0.0202 | 0.0074 |
Entamoeba histolytica | PH domain containing protein | 0.0183 | 0.0129 | 0.0129 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.4499 | 0.669 | 1 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.2225 | 0.3234 | 0.4833 |
Echinococcus multilocularis | dynamin 1 | 0.0183 | 0.0129 | 0.0193 |
Leishmania major | protein kinase, putative,serine/threonine protein kinase, putative | 0.0231 | 0.0202 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0231 | 0.0202 | 0.0074 |
Schistosoma mansoni | hypothetical protein | 0.0183 | 0.0129 | 0.0193 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.2225 | 0.3234 | 0.3234 |
Echinococcus multilocularis | pleckstrin y domain containing family A | 0.0183 | 0.0129 | 0.0193 |
Loa Loa (eye worm) | syntrophin-1 | 0.0183 | 0.0129 | 0.0129 |
Trypanosoma cruzi | Serine/threonine-protein kinase NEK21, putative | 0.0231 | 0.0202 | 0.0302 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.4316 | 0.6412 | 0.9584 |
Plasmodium falciparum | RAC-beta serine/threonine protein kinase | 0.4316 | 0.6412 | 1 |
Entamoeba histolytica | Rho guanine nucleotide exchange factor, putative | 0.0183 | 0.0129 | 0.0129 |
Brugia malayi | Pleckstrin Homology Domain | 0.0183 | 0.0129 | 0.0129 |
Brugia malayi | PH domain containing protein | 0.0183 | 0.0129 | 0.0129 |
Schistosoma mansoni | hypothetical protein | 0.0183 | 0.0129 | 0.0193 |
Echinococcus granulosus | serine/threonine protein kinase | 0.4499 | 0.669 | 1 |
Echinococcus multilocularis | nervana 2 | 0.4268 | 0.6339 | 0.9475 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.0108 | 0.0108 |
Echinococcus multilocularis | oxysterol binding protein 9 | 0.0183 | 0.0129 | 0.0193 |
Trichomonas vaginalis | AGC family protein kinase | 0.6676 | 1 | 1 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.1284 | 0.1802 | 0.2694 |
Plasmodium vivax | rac-beta serine/threonine protein kinase, putative | 0.4316 | 0.6412 | 1 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.6676 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1284 | 0.1802 | 0.1802 |
Echinococcus multilocularis | GRB2 associated binding protein 3 | 0.0183 | 0.0129 | 0.0193 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.4499 | 0.669 | 1 |
Echinococcus multilocularis | protein kinase c iota type | 0.2225 | 0.3234 | 0.4833 |
Entamoeba histolytica | hypothetical protein | 0.0231 | 0.0202 | 0.0202 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.6493 | 0.9722 | 0.9722 |
Echinococcus granulosus | arf GAP with coiled coil ANK repeat and PH | 0.0183 | 0.0129 | 0.0193 |
Entamoeba histolytica | protein kinase, putative | 0.6493 | 0.9722 | 0.9722 |
Echinococcus granulosus | pdz domain containing protein | 0.0183 | 0.0129 | 0.0193 |
Echinococcus multilocularis | oxysterol binding protein 3 | 0.0183 | 0.0129 | 0.0193 |
Entamoeba histolytica | Rho guanine nucleotide exchange factor, putative | 0.0183 | 0.0129 | 0.0129 |
Trichomonas vaginalis | AGC family protein kinase | 0.6676 | 1 | 1 |
Brugia malayi | PH domain containing protein | 0.0183 | 0.0129 | 0.0129 |
Echinococcus granulosus | NDR protein kinase | 0.2225 | 0.3234 | 0.4833 |
Trichomonas vaginalis | AGC family protein kinase | 0.0231 | 0.0202 | 0.0074 |
Trichomonas vaginalis | AGC family protein kinase | 0.2225 | 0.3234 | 0.3145 |
Brugia malayi | PH domain containing protein | 0.0183 | 0.0129 | 0.0129 |
Entamoeba histolytica | hypothetical protein, conserved domain containing | 0.0183 | 0.0129 | 0.0129 |
Echinococcus granulosus | Pleckstrin y | 0.0183 | 0.0129 | 0.0193 |
Onchocerca volvulus | Putative zinc finger protein | 0.0183 | 0.0129 | 1 |
Brugia malayi | PH domain containing protein | 0.0183 | 0.0129 | 0.0129 |
Echinococcus granulosus | ras specific guanine nucleotide releasing factor | 0.0183 | 0.0129 | 0.0193 |
Trypanosoma brucei | Serine/threonine-protein kinase NEK21, putative | 0.0231 | 0.0202 | 0.0074 |
Entamoeba histolytica | protein kinase, putative | 0.2225 | 0.3234 | 0.3234 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Trichomonas vaginalis | AGC family protein kinase | 0.2225 | 0.3234 | 0.3145 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.6493 | 0.9722 | 0.9722 |
Schistosoma mansoni | dynamin | 0.0183 | 0.0129 | 0.0193 |
Onchocerca volvulus | 0.0183 | 0.0129 | 1 | |
Echinococcus multilocularis | pdz domain containing protein | 0.0183 | 0.0129 | 0.0193 |
Brugia malayi | Cytohesin 3 | 0.0183 | 0.0129 | 0.0129 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.2225 | 0.3234 | 0.4833 |
Loa Loa (eye worm) | rho-GTPase-activating | 0.0183 | 0.0129 | 0.0129 |
Schistosoma mansoni | hypothetical protein | 0.0183 | 0.0129 | 0.0193 |
Brugia malayi | Variant SH3 domain containing protein | 0.0183 | 0.0129 | 0.0129 |
Trichomonas vaginalis | AGC family protein kinase | 0.2408 | 0.3512 | 0.3427 |
Entamoeba histolytica | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Echinococcus multilocularis | Pleckstrin y | 0.0183 | 0.0129 | 0.0193 |
Entamoeba histolytica | protein kinase, putative | 0.0231 | 0.0202 | 0.0202 |
Entamoeba histolytica | protein kinase 2, putative | 0.4316 | 0.6412 | 0.6412 |
Trichomonas vaginalis | serine/threonine-protein kinase sgk, putative | 0.2177 | 0.3161 | 0.3071 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.2225 | 0.3234 | 0.4833 |
Schistosoma mansoni | serine/threonine protein kinase | 0.2225 | 0.3234 | 0.4833 |
Echinococcus multilocularis | FERM and pleckstrin domain containing protein | 0.0183 | 0.0129 | 0.0193 |
Loa Loa (eye worm) | hypothetical protein | 0.0267 | 0.0257 | 0.0257 |
Brugia malayi | GTP-ase activating protein for Arf containing protein | 0.0183 | 0.0129 | 0.0129 |
Entamoeba histolytica | Rho guanine nucleotide exchange factor, putative | 0.0183 | 0.0129 | 0.0129 |
Echinococcus multilocularis | oxysterol binding protein 1 | 0.0183 | 0.0129 | 0.0193 |
Brugia malayi | Hr1 repeat family protein | 0.2225 | 0.3234 | 0.3234 |
Echinococcus granulosus | dynamin 1 | 0.0183 | 0.0129 | 0.0193 |
Trypanosoma cruzi | PH domain containing protein, putative | 0.0183 | 0.0129 | 0.0193 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.4268 | 0.6339 | 0.9475 |
Trichomonas vaginalis | AGC family protein kinase | 0.0231 | 0.0202 | 0.0074 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.1043 | 0.1436 | 0.1436 |
Onchocerca volvulus | Putative neuronal RhoA GEF protein | 0.0183 | 0.0129 | 1 |
Echinococcus granulosus | collagen type iv alpha 3 binding protein | 0.0183 | 0.0129 | 0.0193 |
Brugia malayi | PH domain containing protein | 0.0183 | 0.0129 | 0.0129 |
Onchocerca volvulus | 0.0183 | 0.0129 | 1 | |
Trichomonas vaginalis | 3-phosphoinositide dependent protein kinase-1, putative | 0.0231 | 0.0202 | 0.0074 |
Trypanosoma cruzi | hypothetical protein | 0.0183 | 0.0129 | 0.0193 |
Brugia malayi | Oxysterol-binding protein | 0.0183 | 0.0129 | 0.0129 |
Trypanosoma cruzi | ADP-ribosylation factor family, putative | 0.0183 | 0.0129 | 0.0193 |
Schistosoma mansoni | centaurin alpha | 0.0183 | 0.0129 | 0.0193 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Trypanosoma cruzi | hypothetical protein | 0.0183 | 0.0129 | 0.0193 |
Echinococcus multilocularis | actin binding protein anillin | 0.0183 | 0.0129 | 0.0193 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0183 | 0.0129 | 0.0129 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0508 | 0.0624 | 0.0932 |
Echinococcus multilocularis | Pleckstrin y | 0.0183 | 0.0129 | 0.0193 |
Brugia malayi | PH domain containing protein | 0.0183 | 0.0129 | 0.0129 |
Entamoeba histolytica | protein kinase, putative | 0.0231 | 0.0202 | 0.0202 |
Echinococcus multilocularis | Pleckstrin domain containing protein, family B | 0.0183 | 0.0129 | 0.0193 |
Trichomonas vaginalis | AGC family protein kinase | 0.0231 | 0.0202 | 0.0074 |
Onchocerca volvulus | 0.0183 | 0.0129 | 1 | |
Trypanosoma brucei | serine/threonine-protein kinase NrkA | 0.0231 | 0.0202 | 0.0074 |
Trichomonas vaginalis | AGC family protein kinase | 0.6676 | 1 | 1 |
Echinococcus granulosus | protein kinase c epsilon type | 0.2225 | 0.3234 | 0.4833 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0231 | 0.0202 | 0.0202 |
Trypanosoma cruzi | NEK family Serine/threonine-protein kinase, putative | 0.0183 | 0.0129 | 0.0193 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.4268 | 0.6339 | 0.9475 |
Trypanosoma cruzi | Serine/threonine-protein kinase NEK17, putative | 0.0231 | 0.0202 | 0.0302 |
Entamoeba histolytica | protein kinase, putative | 0.0231 | 0.0202 | 0.0202 |
Leishmania major | hypothetical protein, conserved | 0.0183 | 0.0129 | 0.6392 |
Schistosoma mansoni | serine/threonine protein kinase | 0.2225 | 0.3234 | 0.4833 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.2225 | 0.3234 | 0.4833 |
Loa Loa (eye worm) | oxysterol binding protein | 0.0183 | 0.0129 | 0.0129 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.2225 | 0.3234 | 0.3234 |
Trichomonas vaginalis | AGC family protein kinase | 0.0231 | 0.0202 | 0.0074 |
Brugia malayi | protein kinase C II. | 0.2225 | 0.3234 | 0.3234 |
Echinococcus granulosus | Arf GAP and Pleckstrin domain containing protein | 0.0183 | 0.0129 | 0.0193 |
Entamoeba histolytica | hypothetical protein, conserved domain containing | 0.0183 | 0.0129 | 0.0129 |
Onchocerca volvulus | 0.0183 | 0.0129 | 1 | |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.4316 | 0.6412 | 0.9584 |
Trichomonas vaginalis | AGC family protein kinase | 0.0231 | 0.0202 | 0.0074 |
Brugia malayi | Uncoordinated protein 104 | 0.0183 | 0.0129 | 0.0129 |
Schistosoma mansoni | oxysterol-binding protein 1 | 0.0183 | 0.0129 | 0.0193 |
Echinococcus granulosus | beta 1 syntrophin | 0.0183 | 0.0129 | 0.0193 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.2225 | 0.3234 | 0.4833 |
Entamoeba histolytica | protein kinase, putative | 0.0231 | 0.0202 | 0.0202 |
Loa Loa (eye worm) | glutamate receptor | 0.041 | 0.0475 | 0.0475 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0183 | 0.0129 | 0.0193 |
Brugia malayi | PH domain containing protein | 0.0183 | 0.0129 | 0.0129 |
Onchocerca volvulus | Poor gastrulation protein homolog | 0.0169 | 0.0108 | 0.8372 |
Trypanosoma cruzi | PH domain containing protein, putative | 0.0183 | 0.0129 | 0.0193 |
Echinococcus multilocularis | DCC interacting protein 13 beta | 0.0183 | 0.0129 | 0.0193 |
Echinococcus granulosus | calcium dependent secretion activator 1 | 0.0183 | 0.0129 | 0.0193 |
Entamoeba histolytica | Rho guanine nucleotide exchange factor, putative | 0.0183 | 0.0129 | 0.0129 |
Onchocerca volvulus | 0.0183 | 0.0129 | 1 | |
Brugia malayi | Syntrophin-1 | 0.0183 | 0.0129 | 0.0129 |
Trypanosoma cruzi | Protein kinase B | 0.4499 | 0.669 | 1 |
Toxoplasma gondii | calcium dependent protein kinase CDPK7 | 0.0231 | 0.0202 | 0.0076 |
Brugia malayi | Plekhf2 protein | 0.0183 | 0.0129 | 0.0129 |
Schistosoma mansoni | phosphoinositol 4-phosphate adaptor protein | 0.0183 | 0.0129 | 0.0193 |
Schistosoma mansoni | serine/threonine protein kinase | 0.2225 | 0.3234 | 0.4833 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Echinococcus granulosus | nervana 2 | 0.4268 | 0.6339 | 0.9475 |
Trypanosoma cruzi | PH domain containing protein, putative | 0.0183 | 0.0129 | 0.0193 |
Trypanosoma brucei | serine/threonine-protein kinase NRKB, putative | 0.0231 | 0.0202 | 0.0074 |
Echinococcus multilocularis | Rho GTPase activating protein 24 | 0.0183 | 0.0129 | 0.0193 |
Echinococcus multilocularis | Arf GAP and Pleckstrin domain containing protein | 0.0183 | 0.0129 | 0.0193 |
Echinococcus multilocularis | collagen type iv alpha 3 binding protein | 0.0183 | 0.0129 | 0.0193 |
Echinococcus granulosus | oxysterol binding protein 1 | 0.0183 | 0.0129 | 0.0193 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Toxoplasma gondii | AGC kinase | 0.6493 | 0.9722 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.2225 | 0.3234 | 0.4833 |
Trichomonas vaginalis | AGC family protein kinase | 0.0231 | 0.0202 | 0.0074 |
Trichomonas vaginalis | AGC family protein kinase | 0.0231 | 0.0202 | 0.0074 |
Loa Loa (eye worm) | glutamate receptor | 0.1043 | 0.1436 | 0.1436 |
Trichomonas vaginalis | AGC family protein kinase | 0.0231 | 0.0202 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Schistosoma mansoni | rhogef and pleckstrin domain protein | 0.0183 | 0.0129 | 0.0193 |
Schistosoma mansoni | serine/threonine protein kinase | 0.2225 | 0.3234 | 0.4833 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.2225 | 0.3234 | 0.4833 |
Brugia malayi | metabotropic glutamate receptor type 2 | 0.0508 | 0.0624 | 0.0624 |
Giardia lamblia | Kinase, AGC PKA | 0.4316 | 0.6412 | 0.5 |
Onchocerca volvulus | 0.0183 | 0.0129 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Schistosoma mansoni | goodpasture antigen-binding protein | 0.0183 | 0.0129 | 0.0193 |
Echinococcus multilocularis | Oxysterol binding protein 11 | 0.0183 | 0.0129 | 0.0193 |
Schistosoma mansoni | zinc finger protein | 0.0183 | 0.0129 | 0.0193 |
Trichomonas vaginalis | AGC family protein kinase | 0.2225 | 0.3234 | 0.3145 |
Echinococcus granulosus | protein kinase C gamma type | 0.2225 | 0.3234 | 0.4833 |
Brugia malayi | Cadps2 protein | 0.0183 | 0.0129 | 0.0129 |
Onchocerca volvulus | Abnormal cell migration protein 10 homolog | 0.0183 | 0.0129 | 1 |
Schistosoma mansoni | development and differentiation-enhancing factor ddef | 0.0183 | 0.0129 | 0.0193 |
Entamoeba histolytica | Rho guanine nucleotide exchange factor, putative | 0.0183 | 0.0129 | 0.0129 |
Brugia malayi | metabotropic GABA-B receptor subtype 2 | 0.0169 | 0.0108 | 0.0108 |
Trypanosoma brucei | protein kinase, putative | 0.0231 | 0.0202 | 0.0074 |
Loa Loa (eye worm) | GTP-ase activating protein for Arf containing protein | 0.0183 | 0.0129 | 0.0129 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.6676 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.6676 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 0.0108 | 0.0162 |
Echinococcus multilocularis | cytohesin 1 | 0.0183 | 0.0129 | 0.0193 |
Schistosoma mansoni | myotubularin-related protein | 0.0183 | 0.0129 | 0.0193 |
Schistosoma mansoni | dynamin | 0.0183 | 0.0129 | 0.0193 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0874 | 0.1179 | 0.1762 |
Entamoeba histolytica | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Trypanosoma cruzi | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0183 | 0.0129 | 0.0193 |
Trichomonas vaginalis | AGC family protein kinase | 0.0231 | 0.0202 | 0.0074 |
Trichomonas vaginalis | AGC family protein kinase | 0.0231 | 0.0202 | 0.0074 |
Loa Loa (eye worm) | PH domain-containing protein | 0.0183 | 0.0129 | 0.0129 |
Leishmania major | hypothetical protein, conserved | 0.0183 | 0.0129 | 0.6392 |
Echinococcus multilocularis | Pleckstrin y | 0.0183 | 0.0129 | 0.0193 |
Entamoeba histolytica | Rho guanine nucleotide exchange factor, putative | 0.0183 | 0.0129 | 0.0129 |
Entamoeba histolytica | ARF GTPase activating protein, putative | 0.0183 | 0.0129 | 0.0129 |
Loa Loa (eye worm) | cytohesin 3 | 0.0183 | 0.0129 | 0.0129 |
Echinococcus multilocularis | beta 1 syntrophin | 0.0183 | 0.0129 | 0.0193 |
Onchocerca volvulus | outspread protein homolog | 0.0183 | 0.0129 | 1 |
Brugia malayi | Oxysterol binding protein | 0.0183 | 0.0129 | 0.0129 |
Entamoeba histolytica | pleckstrin homology (PH) domain containing protein | 0.0183 | 0.0129 | 0.0129 |
Echinococcus multilocularis | ras specific guanine nucleotide releasing factor | 0.0183 | 0.0129 | 0.0193 |
Trichomonas vaginalis | AGC family protein kinase | 0.0231 | 0.0202 | 0.0074 |
Echinococcus granulosus | cytohesin 1 | 0.0183 | 0.0129 | 0.0193 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0231 | 0.0202 | 0.0202 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.4499 | 0.669 | 1 |
Schistosoma mansoni | oxysterol-binding protein 1 | 0.0183 | 0.0129 | 0.0193 |
Entamoeba histolytica | PH domain containing protein | 0.0183 | 0.0129 | 0.0129 |
Echinococcus multilocularis | serine threonine protein kinase | 0.2225 | 0.3234 | 0.4833 |
Trichomonas vaginalis | AGC family protein kinase | 0.0231 | 0.0202 | 0.0074 |
Leishmania major | folate/biopterin transporter, putative | 0.0231 | 0.0202 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0183 | 0.0129 | 0.0193 |
Plasmodium vivax | calcium-dependent protein kinase 7, putative | 0.0231 | 0.0202 | 0.0116 |
Trypanosoma cruzi | serine/threonine protein kinase, putative | 0.0231 | 0.0202 | 0.0302 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.4268 | 0.6339 | 0.9475 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.2225 | 0.3234 | 0.4833 |
Trypanosoma cruzi | NIMA-related kinase, putative | 0.0231 | 0.0202 | 0.0302 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Echinococcus multilocularis | arf GAP with coiled coil, ANK repeat and PH | 0.0183 | 0.0129 | 0.0193 |
Entamoeba histolytica | p21-activated kinase | 0.0231 | 0.0202 | 0.0202 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0231 | 0.0202 | 0.0202 |
Entamoeba histolytica | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Schistosoma mansoni | serine/threonine protein kinase | 0.2225 | 0.3234 | 0.4833 |
Echinococcus granulosus | Oxysterol binding protein 11 | 0.0183 | 0.0129 | 0.0193 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.4268 | 0.6339 | 0.9475 |
Echinococcus granulosus | type II inositol 34 bisphosphate 4 phosphatase | 0.0183 | 0.0129 | 0.0193 |
Trypanosoma cruzi | NIMA-related kinase, putative | 0.0231 | 0.0202 | 0.0302 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.2225 | 0.3234 | 0.4833 |
Brugia malayi | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Echinococcus granulosus | Pleckstrin y | 0.0183 | 0.0129 | 0.0193 |
Echinococcus multilocularis | calcium dependent secretion activator 1 | 0.0183 | 0.0129 | 0.0193 |
Schistosoma mansoni | hypothetical protein | 0.0183 | 0.0129 | 0.0193 |
Schistosoma mansoni | serine/threonine protein kinase | 0.2225 | 0.3234 | 0.4833 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Trypanosoma cruzi | hypothetical protein | 0.0183 | 0.0129 | 0.0193 |
Trypanosoma cruzi | serine/threonine-protein kinase NRKB, putative | 0.0231 | 0.0202 | 0.0302 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0874 | 0.1179 | 0.1762 |
Trichomonas vaginalis | AGC family protein kinase | 0.0231 | 0.0202 | 0.0074 |
Echinococcus multilocularis | myotubularin protein 13 | 0.0183 | 0.0129 | 0.0193 |
Trypanosoma brucei | NEK family Serine/threonine-protein kinase, putative | 0.0231 | 0.0202 | 0.0074 |
Loa Loa (eye worm) | RhoGEF domain-containing protein | 0.0183 | 0.0129 | 0.0129 |
Onchocerca volvulus | Metabotropic glutamate receptor homolog | 0.0169 | 0.0108 | 0.8372 |
Trypanosoma cruzi | hypothetical protein | 0.0183 | 0.0129 | 0.0193 |
Trypanosoma cruzi | Serine/threonine-protein kinase NEK17, putative | 0.0231 | 0.0202 | 0.0302 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.4316 | 0.6412 | 0.9584 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.4499 | 0.669 | 0.669 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.2225 | 0.3234 | 0.3234 |
Trypanosoma cruzi | hypothetical protein | 0.0183 | 0.0129 | 0.0193 |
Loa Loa (eye worm) | hypothetical protein | 0.2225 | 0.3234 | 0.3234 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0129 | 0.0129 |
Brugia malayi | Protein kinase domain containing protein | 0.2225 | 0.3234 | 0.3234 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 6681 mmHg/s | Ex-vivo cardioprotective activity in BL6 mouse LAD ligation ischemic heart failure model assessed as left ventricular rate of pressure change in isolated heart at 10 uM, sc administered as infusion at 24 hrs post LAD ligation for 28 days (Rvb = 6156 +/- 356 mmHg/s) | ChEMBL. | 23286881 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.