Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tyrosine kinase | 0.0381 | 0.6249 | 0.5744 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0506 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.0381 | 0.6249 | 0.6249 |
Echinococcus multilocularis | tyrosine kinase | 0.0216 | 0.1312 | 0.1312 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0506 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0381 | 0.6249 | 0.5744 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.0234 | 0.1849 | 0.1849 |
Echinococcus multilocularis | c src tyrosine kinase | 0.0381 | 0.6249 | 0.6249 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0334 | 0.4828 | 0.4132 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0294 | 0.3641 | 0.3641 |
Echinococcus granulosus | tyrosine protein kinase ABL1 | 0.0216 | 0.1312 | 0.1312 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0216 | 0.1312 | 0.1312 |
Brugia malayi | Variant SH3 domain containing protein | 0.0334 | 0.4828 | 0.4047 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0506 | 1 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0216 | 0.1312 | 0.1312 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0506 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0234 | 0.1849 | 0.1849 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0506 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0506 | 1 | 1 |
Echinococcus multilocularis | NCK adaptor protein | 0.0334 | 0.4828 | 0.4828 |
Onchocerca volvulus | 0.0216 | 0.1312 | 0.5 | |
Loa Loa (eye worm) | TK protein kinase | 0.0342 | 0.5063 | 0.5063 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0216 | 0.1312 | 0.1312 |
Onchocerca volvulus | 0.0216 | 0.1312 | 0.5 | |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0506 | 1 | 1 |
Echinococcus granulosus | c src tyrosine kinase | 0.0381 | 0.6249 | 0.6249 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0381 | 0.6249 | 0.6249 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0216 | 0.1312 | 0.1312 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0506 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0506 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0342 | 0.5063 | 0.5063 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase abl1 | 0.0334 | 0.4828 | 0.4132 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0506 | 1 | 1 |
Brugia malayi | protein-tyrosine kinase | 0.0342 | 0.5063 | 0.4317 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0381 | 0.6249 | 0.5744 |
Echinococcus granulosus | growth factor receptor bound protein 2 | 0.0334 | 0.4828 | 0.4828 |
Onchocerca volvulus | 0.0216 | 0.1312 | 0.5 | |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0216 | 0.1312 | 0.1312 |
Loa Loa (eye worm) | TK/ABL protein kinase | 0.0216 | 0.1312 | 0.1312 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0334 | 0.4828 | 0.4828 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0234 | 0.1849 | 0.0751 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0506 | 1 | 1 |
Loa Loa (eye worm) | SRC-1 | 0.0506 | 1 | 1 |
Schistosoma mansoni | adapter molecule crk | 0.0334 | 0.4828 | 0.4132 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.0381 | 0.6249 | 0.6249 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0216 | 0.1312 | 0.1312 |
Echinococcus multilocularis | tyrosine protein kinase Fps85D | 0.0216 | 0.1312 | 0.1312 |
Schistosoma mansoni | tyrosine kinase | 0.0216 | 0.1312 | 0.0143 |
Schistosoma mansoni | tyrosine kinase | 0.0506 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0506 | 1 | 1 |
Onchocerca volvulus | 0.0216 | 0.1312 | 0.5 | |
Onchocerca volvulus | 0.0216 | 0.1312 | 0.5 | |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0234 | 0.1849 | 0.1849 |
Echinococcus granulosus | NCK adaptor protein | 0.0334 | 0.4828 | 0.4828 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0234 | 0.1849 | 0.0751 |
Loa Loa (eye worm) | sex muscle abnormal protein 5 | 0.0334 | 0.4828 | 0.4828 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0381 | 0.6249 | 0.5683 |
Echinococcus granulosus | tyrosine protein kinase Srms | 0.0216 | 0.1312 | 0.1312 |
Onchocerca volvulus | 0.0216 | 0.1312 | 0.5 | |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0216 | 0.1312 | 0.1312 |
Brugia malayi | Sex muscle abnormal protein 5 | 0.0334 | 0.4828 | 0.4047 |
Echinococcus granulosus | tyrosine protein kinase Fps85D | 0.0216 | 0.1312 | 0.1312 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0216 | 0.1312 | 0.1312 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0216 | 0.1312 | 0.1312 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0342 | 0.5063 | 0.5063 |
Echinococcus granulosus | tyrosine kinase | 0.0216 | 0.1312 | 0.1312 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0506 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0506 | 1 | 1 |
Echinococcus multilocularis | growth factor receptor bound protein 2 | 0.0334 | 0.4828 | 0.4828 |
Schistosoma mansoni | nck2/grb4 | 0.0334 | 0.4828 | 0.4132 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0342 | 0.5063 | 0.5063 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0506 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0234 | 0.1849 | 0.1849 |
Echinococcus multilocularis | tyrosine protein kinase shark | 0.0216 | 0.1312 | 0.1312 |
Schistosoma mansoni | tyrosine kinase | 0.0216 | 0.1312 | 0.0143 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0216 | 0.1312 | 0.1312 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0506 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0342 | 0.5063 | 0.5063 |
Brugia malayi | Variant SH3 domain containing protein | 0.0334 | 0.4828 | 0.4047 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.0216 | 0.1312 | 1 |
Echinococcus granulosus | tyrosine protein kinase shark | 0.0216 | 0.1312 | 0.1312 |
Echinococcus granulosus | tyrosine kinase | 0.0342 | 0.5063 | 0.5063 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.1312 | 0.1312 |
Loa Loa (eye worm) | hypothetical protein | 0.0334 | 0.4828 | 0.4828 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0334 | 0.4828 | 0.4132 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0342 | 0.5063 | 0.5063 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0234 | 0.1849 | 0.0751 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0506 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0294 | 0.3641 | 0.3641 |
Echinococcus multilocularis | tyrosine protein kinase ABL1 | 0.0216 | 0.1312 | 0.1312 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0506 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.