Detailed information for compound 1742508

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 871.983 | Formula: C39H61N13O10
  • H donors: 12 H acceptors: 11 LogP: -4.17 Rotable bonds: 32
    Rule of 5 violations (Lipinski): 4
  • SMILES: CC[C@@H]([C@@H](C(=O)N[C@H](C(=O)N(CC(=O)N)C)Cc1nc[nH]c1)NC(=O)[C@@H](NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)N)CCCN=C(N)N)Cc1ccc(cc1)O)C
  • InChi: 1S/C39H61N13O10/c1-6-21(4)32(37(61)49-28(15-23-17-44-19-46-23)38(62)52(5)18-29(41)54)51-35(59)27(14-22-9-11-24(53)12-10-22)48-36(60)31(20(2)3)50-34(58)26(8-7-13-45-39(42)43)47-33(57)25(40)16-30(55)56/h9-12,17,19-21,25-28,31-32,53H,6-8,13-16,18,40H2,1-5H3,(H2,41,54)(H,44,46)(H,47,57)(H,48,60)(H,49,61)(H,50,58)(H,51,59)(H,55,56)(H4,42,43,45)/t21-,25-,26-,27-,28-,31-,32-/m0/s1
  • InChiKey: QNQQNWTYHUHDMV-VJRZEHHUSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus granulosus histone acetyltransferase KAT2B 0.0137 0.0413 0.0403
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0041 0.0034 0.0051
Brugia malayi Peptidase family M1 containing protein 0.0136 0.0411 0.0885
Loa Loa (eye worm) hypothetical protein 0.0041 0.0034 0.002
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0041 0.0034 0.0023
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0599 0.2238 1
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0533 0.1463
Loa Loa (eye worm) hypothetical protein 0.0041 0.0034 0.002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0041 0.0034 0.002
Brugia malayi Pre-SET motif family protein 0.0839 0.3185 0.7027
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.0036 0.0145
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0088 0.0222 0.2031
Echinococcus multilocularis lamin 0.0079 0.0185 0.0174
Loa Loa (eye worm) hypothetical protein 0.0199 0.0658 0.0645
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0121 0.0352 0.0352
Brugia malayi RNA binding protein 0.0062 0.0116 0.0233
Echinococcus granulosus tar DNA binding protein 0.0062 0.0116 0.0105
Brugia malayi hypothetical protein 0.1179 0.4529 1
Brugia malayi TAR-binding protein 0.0062 0.0116 0.0233
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0064 0.0124 0.0788
Onchocerca volvulus 0.005 0.0071 0.0151
Toxoplasma gondii histone lysine methyltransferase SET1 0.0115 0.0327 0.1997
Echinococcus granulosus jumonji domain containing 1A 0.0064 0.0124 0.0113
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0546 0.2027 0.2019
Echinococcus granulosus lysine specific demethylase 6a 0.0064 0.0124 0.0113
Loa Loa (eye worm) hypothetical protein 0.0136 0.0411 0.0398
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.0036 0.0452
Schistosoma mansoni hypothetical protein 0.0806 0.3056 0.3056
Trypanosoma cruzi aminopeptidase, putative 0.0136 0.0411 0.2846
Plasmodium vivax amine transporter, putative 0.005 0.0071 0.1236
Echinococcus multilocularis phd:f box containing protein 0.0064 0.0124 0.0113
Echinococcus granulosus geminin 0.086 0.3269 0.3261
Loa Loa (eye worm) hypothetical protein 0.0036 0.0016 0.0003
Loa Loa (eye worm) hypothetical protein 0.0121 0.0352 0.0339
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0124 0.0364 0.0364
Brugia malayi Peptidase family M1 containing protein 0.0136 0.0411 0.0885
Plasmodium falciparum JmjC domain-containing protein, putative 0.0064 0.0124 0.2304
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0533 0.1463
Brugia malayi intermediate filament protein 0.0079 0.0185 0.0385
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0069 0.0144 0.083
Schistosoma mansoni cpg binding protein 0.006 0.0109 0.0109
Echinococcus granulosus PHD finger protein rhinoceros 0.0149 0.0461 0.045
Brugia malayi AF-10 protein 0.0049 0.0065 0.012
Schistosoma mansoni alpha-glucosidase 0.0138 0.0419 0.0419
Loa Loa (eye worm) hypothetical protein 0.0041 0.0034 0.002
Brugia malayi hypothetical protein 0.0136 0.0411 0.0885
Loa Loa (eye worm) hypothetical protein 0.0041 0.0034 0.002
Loa Loa (eye worm) hypothetical protein 0.0235 0.0802 0.0789
Trypanosoma cruzi arginine N-methyltransferase, type III 0.0055 0.0092 0.0561
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.005 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0036 0.0016 0.0003
Schistosoma mansoni steroid hormone receptor ad4bp 0.0041 0.0034 0.0034
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0106 0.0885
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0124 0.011
Schistosoma mansoni retinoic acid receptor RXR 0.0041 0.0034 0.0034
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0136 0.0411 0.04
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0041 0.0034 0.0023
Loa Loa (eye worm) hypothetical protein 0.005 0.0071 0.0058
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0016 0.0045
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0109 0.0303 0.0292
Toxoplasma gondii aminopeptidase N, putative 0.0136 0.0411 0.2529
Treponema pallidum fructose-bisphosphate aldolase 0.0599 0.2238 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0065 0.0065
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0041 0.0034 0.0048
Trichomonas vaginalis set domain proteins, putative 0.0955 0.3642 1
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0069 0.0144 0.0133
Echinococcus granulosus aminopeptidase N 0.0136 0.0411 0.04
Loa Loa (eye worm) hypothetical protein 0.0271 0.0942 0.0929
Echinococcus multilocularis sodium and chloride dependent glycine 0.005 0.0071 0.006
Mycobacterium ulcerans aminopeptidase N PepN 0.0136 0.0411 0.3899
Brugia malayi steroid hormone receptor 0.0041 0.0034 0.0051
Echinococcus multilocularis FTZ F1 alpha 0.0041 0.0034 0.0023
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0016 0.0005
Loa Loa (eye worm) hypothetical protein 0.0149 0.0461 0.0448
Brugia malayi nuclear receptor NHR-88 0.0041 0.0034 0.0051
Entamoeba histolytica arginine N-methyltransferase protein, putative 0.0088 0.0219 0.0935
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0136 0.0411 0.2846
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0389 0.1409 0.3095
Echinococcus multilocularis serotonin transporter 0.0296 0.1042 0.1032
Brugia malayi hypothetical protein 0.0711 0.268 0.5909
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0088 0.0219 0.1473
Schistosoma mansoni alpha glucosidase 0.0036 0.0014 0.0014
Plasmodium falciparum transporter, putative 0.005 0.0071 0.1106
Loa Loa (eye worm) hypothetical protein 0.0088 0.0219 0.0206
Schistosoma mansoni lamin 0.0079 0.0185 0.0185
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0296 0.1042 0.2282
Echinococcus multilocularis dnaJ subfamily B 0.0806 0.3056 0.3048
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0106 0.0751
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0043 0.0041 0.0041
Brugia malayi jmjC domain containing protein 0.0241 0.0826 0.1805
Brugia malayi proteasome subunit beta type 1 0.0069 0.0144 0.0295
Echinococcus multilocularis survival motor neuron protein 1 0.0711 0.268 0.2673
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0064 0.0124 0.0124
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0034 0.0051
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0043 0.0041 0.0041
Loa Loa (eye worm) TATA binding protein associated factor 0.0136 0.0411 0.0398
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0136 0.0411 0.2915
Loa Loa (eye worm) hypothetical protein 0.0037 0.0017 0.0004
Plasmodium vivax proteasome subunit beta type-1, putative 0.0069 0.0144 0.2874
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0121 0.0352 0.0352
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0052 0.0078 0.1274
Brugia malayi Sodium:neurotransmitter symporter family protein 0.005 0.0071 0.0134
Trypanosoma brucei Aminopeptidase M1, putative 0.0136 0.0411 0.2846
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0136 0.0411 0.04
Schistosoma mansoni hypothetical protein 0.0109 0.0303 0.0303
Brugia malayi jmjC domain containing protein 0.0064 0.0124 0.025
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.005 0.0071 0.0071
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0041 0.0034 0.0023
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0136 0.0411 0.2846
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0016 0.0012
Echinococcus multilocularis cpg binding protein 0.006 0.0109 0.0098
Onchocerca volvulus 0.0079 0.0185 0.0464
Brugia malayi hypothetical protein 0.0136 0.0411 0.0885
Echinococcus granulosus sodium and chloride dependent glycine 0.005 0.0071 0.006
Toxoplasma gondii aminopeptidase n, putative 0.0136 0.0411 0.2529
Loa Loa (eye worm) hypothetical protein 0.0109 0.0303 0.029
Echinococcus multilocularis protein arginine N methyltransferase 7 0.0055 0.0092 0.0081
Brugia malayi Pre-SET motif family protein 0.0121 0.0352 0.0755
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0041 0.0034 0.0023
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0141 0.0429 0.0429
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0136 0.0411 0.2915
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0879 0.2413
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0043 0.0041 0.0195
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0016 0.0019
Echinococcus granulosus protein arginine N methyltransferase 8 0.0059 0.0105 0.0094
Onchocerca volvulus 0.0955 0.3642 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0041 0.0034 0.0023
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0067 0.0136 0.0126
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0136 0.0411 0.2915
Echinococcus granulosus GPCR family 2 0.0109 0.0303 0.0292
Echinococcus multilocularis musashi 0.0079 0.0185 0.0174
Loa Loa (eye worm) hypothetical protein 0.0036 0.0016 0.0003
Schistosoma mansoni hypothetical protein 0.0035 0.0011 0.0011
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0016 0.0045
Loa Loa (eye worm) aminopeptidase N 0.0136 0.0411 0.0398
Schistosoma mansoni lamin 0.0079 0.0185 0.0185
Toxoplasma gondii histone arginine methyltransferase PRMT1 0.0059 0.0105 0.0582
Leishmania major proteasome beta 2 subunit, putative 0.0043 0.0041 0.0289
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0041 0.0034 0.002
Onchocerca volvulus 0.0057 0.0096 0.0221
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.005 0.0071 0.0367
Loa Loa (eye worm) MH2 domain-containing protein 0.0237 0.0807 0.0794
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0041 0.0034 0.0034
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0136 0.0411 0.0411
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0136 0.0411 0.2846
Toxoplasma gondii PHD-finger domain-containing protein 0.0149 0.0461 0.2847
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.0034 0.0051
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0116 0.0116
Echinococcus multilocularis lamin dm0 0.0079 0.0185 0.0174
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.005 0.0071 0.006
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0043 0.0041 0.0112
Schistosoma mansoni hypothetical protein 0.0049 0.0065 0.0065
Loa Loa (eye worm) RNA binding protein 0.0062 0.0116 0.0102
Loa Loa (eye worm) proteasome subunit beta type 1 0.0069 0.0144 0.0131
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0069 0.0144 0.0934
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0041 0.0034 0.0034
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0043 0.0041 0.0173
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0059 0.0105 0.0288
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0067 0.0136 0.0126
Brugia malayi nuclear hormone receptor 0.0041 0.0034 0.0051
Echinococcus multilocularis leukotriene A 4 hydrolase 0.2564 1 1
Onchocerca volvulus Glucosylceramidase homolog 0.0167 0.0533 0.1425
Loa Loa (eye worm) solute carrier family 6 member 4 0.0296 0.1042 0.1029
Brugia malayi Steroid receptor seven-up type 2 0.0041 0.0034 0.0051
Toxoplasma gondii hypothetical protein 0.005 0.0071 0.0367
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0879 0.2413
Brugia malayi jmjC domain containing protein 0.0064 0.0124 0.025
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0034 0.0051
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0116 0.0102
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0232 0.079 0.7643
Onchocerca volvulus Alhambra homolog 0.0149 0.0461 0.1225
Mycobacterium ulcerans aminopeptidase N PepN 0.0136 0.0411 0.3899
Loa Loa (eye worm) beta-lactamase 0.0036 0.0016 0.0003
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0088 0.0222 0.1492
Loa Loa (eye worm) hypothetical protein 0.005 0.0071 0.0058
Plasmodium vivax proteasome subunit beta type-2, putative 0.0043 0.0041 0.0552
Echinococcus multilocularis geminin 0.086 0.3269 0.3261
Brugia malayi PHD-finger family protein 0.0149 0.0461 0.0996
Loa Loa (eye worm) hypothetical protein 0.0079 0.0185 0.0171
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0014 0.0096
Schistosoma mansoni hypothetical protein 0.0145 0.0445 0.0445
Giardia lamblia Fructose-bisphosphate aldolase 0.0599 0.2238 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0065 0.0065
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0011 0.0011
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0034 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0041 0.0034 0.0051
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0109 0.0303 0.0646
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0036 0.0026
Loa Loa (eye worm) protein arginine N-methyltransferase 0.0055 0.0092 0.0078
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0055 0.0092 0.0252
Echinococcus multilocularis thyroid hormone receptor alpha 0.0041 0.0034 0.0023
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0106 0.0885
Loa Loa (eye worm) hypothetical protein 0.0041 0.0034 0.002
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0034 0.0023
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0116 0.0116
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0041 0.0034 0.0051
Loa Loa (eye worm) hypothetical protein 0.005 0.0071 0.0058
Brugia malayi Proteasome A-type and B-type family protein 0.0088 0.0222 0.0467
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0069 0.0144 0.0144
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0069 0.0144 0.0133
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0136 0.0411 0.8878
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0136 0.0411 0.04
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0065 0.0065
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.005 0.0071 0.006
Schistosoma mansoni aminopeptidase A (M01 family) 0.0136 0.0411 0.0411
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0088 0.0222 0.1492
Toxoplasma gondii histone arginine methyltransferase PRMT4/CARM1 0.0433 0.1584 1
Echinococcus granulosus sodium and chloride dependent glycine 0.005 0.0071 0.006
Echinococcus granulosus proteasome prosome macropain 0.0088 0.0222 0.0211
Loa Loa (eye worm) hypothetical protein 0.005 0.0071 0.0058
Echinococcus multilocularis protein arginine N methyltransferase 8 0.0059 0.0105 0.0094
Echinococcus granulosus methyltransferase protein 5 0.0055 0.0092 0.0081
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0568 0.156
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0136 0.0411 0.0411
Giardia lamblia Proteasome subunit beta type 2 0.0043 0.0041 0.0082
Trypanosoma cruzi 20S proteasome subunit 0.0043 0.0041 0.0195
Loa Loa (eye worm) leukotriene A4 hydrolase 0.2564 1 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0124 0.011
Loa Loa (eye worm) jmjC domain-containing protein 0.0241 0.0826 0.0814
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0014 0.0037
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0065 0.0054
Schistosoma mansoni hypothetical protein 0.0109 0.0303 0.0303
Brugia malayi Sodium:neurotransmitter symporter family protein 0.005 0.0071 0.0134
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0121 0.0352 0.2155
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0599 0.2238 0.6144
Echinococcus multilocularis lysine specific demethylase 6a 0.0064 0.0124 0.0113
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0121 0.0352 0.0352
Plasmodium vivax hypothetical protein, conserved 0.0149 0.0461 1
Brugia malayi PHD-finger family protein 0.0052 0.0078 0.0148
Brugia malayi TATA binding protein associated factor 0.0136 0.0411 0.0885
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0136 0.0411 0.2915
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0106 0.0106
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0038 0.0023 0.0012
Brugia malayi jmjC domain containing protein 0.0064 0.0124 0.025
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0059 0.0105 0.0288
Echinococcus multilocularis GPCR, family 2 0.0109 0.0303 0.0292
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.005 0.0071 0.0058
Plasmodium vivax JmjC domain containing protein 0.0064 0.0124 0.2416
Echinococcus multilocularis sodium and chloride dependent glycine 0.005 0.0071 0.006
Echinococcus multilocularis JmjC domain containing protein 4 0.0064 0.0124 0.0113
Loa Loa (eye worm) acetyltransferase 0.0141 0.0429 0.0416
Mycobacterium ulcerans proteasome PrcB 0.0088 0.0222 0.2031
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0136 0.0411 0.8862
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0839 0.3185 0.3176
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0059 0.0105 0.0105
Brugia malayi ecdysteroid receptor 0.0041 0.0034 0.0051
Schistosoma mansoni survival motor neuron protein 0.0145 0.0445 0.0445
Schistosoma mansoni hypothetical protein 0.0055 0.0092 0.0092
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0149 0.0461 0.0461
Loa Loa (eye worm) Carm1-pending protein 0.0433 0.1584 0.1572
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0041 0.0034 0.0023
Brugia malayi beta-lactamase family protein 0.0036 0.0016 0.0012
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0023 0.0053
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0296 0.1042 0.1042
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0136 0.0411 0.0411
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0533 0.1463
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0014 0.0037
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0136 0.0411 0.04
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0034 0.0051
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0116 0.0105
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0016 0.0016
Entamoeba histolytica hypothetical protein 0.0088 0.0219 0.0935
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0109 0.0303 0.0292
Loa Loa (eye worm) hypothetical protein 0.0036 0.0016 0.0003
Loa Loa (eye worm) PHD-finger family protein 0.0149 0.0461 0.0448
Schistosoma mansoni phd/f-box containing protein 0.0064 0.0124 0.0124
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0014 0.0003
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.0065 0.0051
Onchocerca volvulus 0.005 0.0071 0.0151
Echinococcus multilocularis proteasome (prosome, macropain) 0.0088 0.0222 0.0211
Toxoplasma gondii PHD-finger domain-containing protein 0.0149 0.0461 0.2847
Onchocerca volvulus 0.0296 0.1042 0.2828
Brugia malayi Latrophilin receptor protein 2 0.0109 0.0303 0.0646
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0016 0.0019
Echinococcus granulosus dnaJ subfamily B 0.0806 0.3056 0.3048
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0599 0.2238 0.6144
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0136 0.0411 0.2846
Schistosoma mansoni jumonji domain containing protein 0.0064 0.0124 0.0124
Echinococcus granulosus peregrin 0.0152 0.0474 0.0464
Plasmodium vivax protein arginine N-methyltransferase 1, putative 0.0059 0.0105 0.1998
Plasmodium falciparum protein arginine N-methyltransferase 1 0.0059 0.0105 0.188
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0041 0.0034 0.0051
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0041 0.0034 0.002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0599 0.2238 0.6144
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0069 0.0144 0.2768
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0038 0.0023 0.0012
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0088 0.0222 0.1492
Onchocerca volvulus 0.0136 0.0411 0.1088
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0055 0.0092 0.0252
Brugia malayi Glycosyl hydrolases family 31 protein 0.0161 0.0507 0.1099
Trichomonas vaginalis esterase, putative 0.0036 0.0016 0.0045
Brugia malayi cytoplasmic intermediate filament protein 0.0042 0.004 0.0064
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0088 0.0222 0.0947
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.005 0.0071 0.0071
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.005 0.0071 0.0071
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0016 0.0016
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0255 0.0879 0.1921
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0106 0.0885
Plasmodium vivax hypothetical protein, conserved 0.005 0.0071 0.1236
Echinococcus granulosus protein arginine N methyltransferase 7 0.0055 0.0092 0.0081
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0109 0.0303 0.0292
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0034 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0879 0.2413
Brugia malayi F/Y-rich N-terminus family protein 0.007 0.0151 0.0309
Toxoplasma gondii hypothetical protein 0.005 0.0071 0.0367
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0049 0.0065 0.0368
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0064 0.0124 0.0701
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0041 0.0034 0.0034
Onchocerca volvulus 0.0378 0.1365 0.3719
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.005 0.0071 0.0134
Loa Loa (eye worm) peptidase family M1 containing protein 0.0136 0.0411 0.0398
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0014 0.0037
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0293 0.1028 1
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0014 0.0003
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0116 0.0233
Trypanosoma brucei protein arginine n-methyltransferase 7 0.0055 0.0092 0.0561
Echinococcus granulosus JmjC domain containing protein 4 0.0064 0.0124 0.0113
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.2564 1 1
Leishmania major arginine N-methyltransferase, type I 0.0055 0.0092 0.0651
Onchocerca volvulus Protein ultraspiracle homolog 0.0041 0.0034 0.0048
Loa Loa (eye worm) hypothetical protein 0.0052 0.0078 0.0064
Schistosoma mansoni protein phosphatase 2C 0.0064 0.0124 0.0124
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0034 0.0034
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.005 0.0071 0.006
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0879 0.2413
Echinococcus multilocularis protein arginine methyltransferase 0.0059 0.0105 0.0094
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.005 0.0071 0.0367
Brugia malayi acetyltransferase, GNAT family protein 0.0141 0.0429 0.0926
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0788 0.2985 0.2978
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0034 0.0051
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0106 0.0095
Brugia malayi photoreceptor-specific nuclear receptor 0.0041 0.0034 0.0051
Schistosoma mansoni hypothetical protein 0.0149 0.0461 0.0461
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0036 0.01
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0599 0.2238 0.6144
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0088 0.0222 0.0609
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0034 0.0051
Echinococcus granulosus jumonji domain containing protein 0.0207 0.0691 0.0681
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0043 0.0041 0.0134
Loa Loa (eye worm) steroid hormone receptor 0.0041 0.0034 0.002
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0043 0.0041 0.0112
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0121 0.0352 0.0342
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0088 0.0222 0.0209
Loa Loa (eye worm) hypothetical protein 0.0041 0.0034 0.002
Echinococcus multilocularis histone arginine methyltransferase CARMER 0.0433 0.1584 0.1575
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0065 0.0054
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0014 0.0037
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0116 0.0116
Plasmodium vivax SET domain protein, putative 0.0121 0.0352 0.7557
Echinococcus multilocularis peregrin 0.0152 0.0474 0.0464
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0069 0.0144 0.1021
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0088 0.0219 0.1473
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0293 0.1028 1
Leishmania major proteasome beta 5 subunit, putative 0.0088 0.0222 0.1574
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.0036 0.01
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0016 0.0005
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0138 0.0138
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0065 0.0054
Echinococcus granulosus survival motor neuron protein 1 0.0711 0.268 0.2673
Echinococcus granulosus lamin 0.0079 0.0185 0.0174
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0041 0.0034 0.0051
Loa Loa (eye worm) hypothetical protein 0.0036 0.0016 0.0003
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0136 0.0411 0.8878
Brugia malayi Peptidase family M1 containing protein 0.0136 0.0411 0.0885
Brugia malayi Bromodomain containing protein 0.0152 0.0474 0.1026
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0599 0.2238 0.6144
Toxoplasma gondii aminopeptidase N protein 0.0136 0.0411 0.2529
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0599 0.2238 0.6144
Schistosoma mansoni RAR-like nuclear receptor 0.0041 0.0034 0.0034
Plasmodium falciparum proteasome subunit beta type-5 0.0088 0.0222 0.4547
Onchocerca volvulus Bile acid receptor homolog 0.0041 0.0034 0.0048
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0121 0.0352 0.0352
Onchocerca volvulus Huntingtin homolog 0.0251 0.0864 0.2338
Loa Loa (eye worm) hypothetical protein 0.005 0.0071 0.0058
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0069 0.0144 0.0598
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0059 0.0105 0.0105
Leishmania major arginine N-methyltransferase, type III, putative;with=GeneDB:Tb927.7.5490 0.0055 0.0092 0.0651
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0055 0.0092 0.0561
Brugia malayi proteasome subunit beta type 2 0.0043 0.0041 0.0066
Loa Loa (eye worm) hypothetical protein 0.0036 0.0016 0.0003
Echinococcus granulosus uncharacterized sodium dependent transporter 0.005 0.0071 0.006
Loa Loa (eye worm) hypothetical protein 0.0389 0.1409 0.1398
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0088 0.0222 0.0222
Giardia lamblia Proteasome subunit beta type 1 0.0069 0.0144 0.0547
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0136 0.0411 0.04
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0043 0.0041 0.003
Plasmodium falciparum phd finger protein, putative 0.0149 0.0461 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0599 0.2238 0.6144
Loa Loa (eye worm) hypothetical protein 0.0037 0.0017 0.0004
Brugia malayi Intermediate filament tail domain containing protein 0.0079 0.0185 0.0385
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0136 0.0411 0.2846
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0136 0.0411 0.04
Loa Loa (eye worm) hypothetical protein 0.005 0.0071 0.0058
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0136 0.0411 0.8862
Entamoeba histolytica aminopeptidase, putative 0.0136 0.0411 0.1796
Brugia malayi jmjC domain containing protein 0.0546 0.2027 0.4463
Loa Loa (eye worm) serotonin transporter b 0.0296 0.1042 0.1029
Loa Loa (eye worm) hypothetical protein 0.0711 0.268 0.2671
Plasmodium vivax proteasome subunit beta type-5, putative 0.0088 0.0222 0.4626
Onchocerca volvulus 0.0079 0.0185 0.0464
Leishmania major C-8 sterol isomerase-like protein 0.0389 0.1409 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0121 0.0352 0.0342
Trypanosoma cruzi aminopeptidase, putative 0.0136 0.0411 0.2846
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0546 0.2027 0.2019
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0136 0.0411 0.04
Brugia malayi Calcitonin receptor-like protein seb-1 0.0344 0.1232 0.2702
Schistosoma mansoni hypothetical protein 0.0235 0.0802 0.0802
Schistosoma mansoni jumonji/arid domain-containing protein 0.0241 0.0826 0.0826
Schistosoma mansoni hypothetical protein 0.0109 0.0303 0.0303
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0533 0.1463
Giardia lamblia PHD finger protein 15 0.0149 0.0461 0.1977
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0568 0.156
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0255 0.0879 0.0866
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0041 0.0034 0.002
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0014 0.0037
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0014 0.0012
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0041 0.0034 0.0023
Echinococcus multilocularis jumonji domain containing 1A 0.0064 0.0124 0.0113
Leishmania major hypothetical protein, conserved 0.0064 0.0124 0.0877
Onchocerca volvulus Huntingtin homolog 0.0251 0.0864 0.2338
Echinococcus multilocularis lysosomal alpha glucosidase 0.0161 0.0507 0.0497
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0042 0.004 0.0026
Trypanosoma brucei Protein arginine N-methyltransferase 1 catalytic subunit 0.0088 0.0219 0.1473
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0109 0.0303 0.0292
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0124 0.011
Schistosoma mansoni cpg binding protein 0.0057 0.0096 0.0096
Loa Loa (eye worm) proteasome subunit beta type 2 0.0043 0.0041 0.0027
Loa Loa (eye worm) hypothetical protein 0.0064 0.0124 0.011
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0041 0.0034 0.0034
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0136 0.0411 0.04
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0043 0.0041 0.003
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0064 0.0124 0.0788
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0136 0.0411 0.1128
Echinococcus granulosus protein arginine methyltransferase 0.0059 0.0105 0.0094
Leishmania major hypothetical protein, conserved 0.0036 0.0016 0.0115
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0879 0.2413
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0016 0.0045
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0064 0.0124 0.0788
Loa Loa (eye worm) hypothetical protein 0.0296 0.1042 0.1029
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0096 0.0083
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0049 0.0065 0.0368
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.005 0.0071 0.006
Schistosoma mansoni sodium/chloride dependent transporter 0.005 0.0071 0.0071
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0014 0.0037
Schistosoma mansoni cpg binding protein 0.006 0.0109 0.0109
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0106 0.0106
Loa Loa (eye worm) norepinephrine transporter 0.0296 0.1042 0.1029
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0043 0.0041 0.0195
Echinococcus granulosus cpg binding protein 0.006 0.0109 0.0098
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0389 0.1409 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0344 0.1232 0.122
Loa Loa (eye worm) hypothetical protein 0.0136 0.0411 0.0398
Loa Loa (eye worm) intermediate filament protein 0.0079 0.0185 0.0171
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0533 0.1463
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0041 0.0034 0.0051
Echinococcus granulosus uncharacterized sodium dependent transporter 0.005 0.0071 0.006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0041 0.0034 0.002
Echinococcus multilocularis aminopeptidase N 0.0136 0.0411 0.04
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0069 0.0144 0.0934
Trypanosoma brucei Aminopeptidase M1, putative 0.0136 0.0411 0.2846
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0079 0.0185 0.0171
Loa Loa (eye worm) hypothetical protein 0.0136 0.0411 0.0398
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0145 0.0445 0.0962
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.005 0.0071 0.0071
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0533 0.1463
Loa Loa (eye worm) hypothetical protein 0.0041 0.0034 0.002
Toxoplasma gondii proteasome subunit beta type, putative 0.0088 0.0222 0.1326
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0088 0.0222 0.0899
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0064 0.0124 0.0701
Echinococcus multilocularis lysine specific demethylase 5A 0.0238 0.0813 0.0803
Loa Loa (eye worm) hypothetical protein 0.0078 0.0179 0.0165
Onchocerca volvulus 0.005 0.0071 0.0151
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.0036 0.0145
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0014 0.0037
Onchocerca volvulus 0.0093 0.024 0.0617
Echinococcus granulosus histone lysine methyltransferase setb 0.0121 0.0352 0.0342
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.005 0.0071 0.0071
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0065 0.0054
Schistosoma mansoni sodium/chloride dependent transporter 0.005 0.0071 0.0071
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0016 0.0003
Toxoplasma gondii ABC1 family protein 0.0036 0.0016 0.0017
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0879 0.2413
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0088 0.0222 0.2031
Toxoplasma gondii histone arginine methyltransferase PRMT3 0.0055 0.0092 0.0498
Trypanosoma brucei aminopeptidase, putative 0.0136 0.0411 0.2846
Brugia malayi Sodium:neurotransmitter symporter family protein 0.005 0.0071 0.0134
Loa Loa (eye worm) latrophilin receptor protein 2 0.0109 0.0303 0.029
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0116 0.033 0.0319
Schistosoma mansoni jumonji/arid domain-containing protein 0.0241 0.0826 0.0826
Schistosoma mansoni intermediate filament proteins 0.0079 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.0344 0.1232 0.122
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0014 0.0006
Echinococcus granulosus lysine specific demethylase 5A 0.0241 0.0826 0.0816
Trypanosoma cruzi Aminopeptidase M1, putative 0.0136 0.0411 0.2846
Onchocerca volvulus 0.0145 0.0445 0.1184
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.005 0.0071 0.0367
Schistosoma mansoni sodium/chloride dependent transporter 0.0296 0.1042 0.1042
Brugia malayi latrophilin 2 splice variant baaae 0.0235 0.0802 0.1751
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0041 0.0034 0.0023
Toxoplasma gondii bicoid-interacting protein BIN3 0.0055 0.0092 0.0498
Echinococcus multilocularis jumonji domain containing protein 0.0207 0.0691 0.0681
Brugia malayi beta-lactamase family protein 0.0036 0.0016 0.0012
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0049 0.0065 0.0327
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0293 0.1028 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0034 0.0051
Loa Loa (eye worm) hypothetical protein 0.0038 0.0023 0.001
Loa Loa (eye worm) jmjC domain-containing protein 0.0307 0.1087 0.1074
Schistosoma mansoni alpha-glucosidase 0.0138 0.0419 0.0419
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0014 0.0037
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0141 0.0429 0.0419
Brugia malayi Protein arginine N-methyltransferase 0.0055 0.0092 0.0179
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0136 0.0411 0.1128
Toxoplasma gondii PHD-finger domain-containing protein 0.0049 0.0065 0.0327
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0014 0.0037
Echinococcus granulosus FTZ F1 alpha 0.0041 0.0034 0.0023
Brugia malayi hypothetical protein 0.0088 0.0219 0.0461
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0041 0.0034 0.0023
Schistosoma mansoni phosphatidylserine receptor 0.0064 0.0124 0.0124
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.005 0.0071 0.5
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0136 0.0411 0.04
Echinococcus multilocularis PHD finger protein rhinoceros 0.0149 0.0461 0.045
Onchocerca volvulus 0.0041 0.0034 0.0048
Schistosoma mansoni hypothetical protein 0.086 0.3269 0.3269
Loa Loa (eye worm) hypothetical protein 0.0041 0.0034 0.002
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.0533 0.1463
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0106 0.0885
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0069 0.0144 0.0395
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0041 0.0034 0.0023
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0014 0.0012
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0116 0.0116
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0055 0.0092 0.0561
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0116 0.0116
Schistosoma mansoni jumonji domain containing protein 0.0445 0.1632 0.1632
Schistosoma mansoni sodium-dependent amino acid transporter 0.005 0.0071 0.0071
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0041 0.0034 0.0034
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0344 0.1232 0.2702
Brugia malayi MH2 domain containing protein 0.0237 0.0807 0.1762
Schistosoma mansoni hypothetical protein 0.0109 0.0303 0.0303
Echinococcus granulosus phd:f box containing protein 0.0064 0.0124 0.0113
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.0065 0.0119
Loa Loa (eye worm) hypothetical protein 0.0296 0.1042 0.1029
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0034 0.0023
Echinococcus multilocularis lysosomal alpha glucosidase 0.0161 0.0507 0.0497
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0599 0.2238 1
Brugia malayi hypothetical protein 0.005 0.0071 0.0134
Schistosoma mansoni nuclear hormone receptor 0.0041 0.0034 0.0034
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0041 0.0034 0.002
Plasmodium vivax hypothetical protein, conserved 0.0052 0.0078 0.1401
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0016 0.0019
Loa Loa (eye worm) hypothetical protein 0.0251 0.0864 0.0852
Brugia malayi beta-lactamase 0.0036 0.0016 0.0012
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0136 0.0411 0.04
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0136 0.0411 0.04
Schistosoma mansoni protein arginine n-methyltransferase 0.0433 0.1584 0.1584
Echinococcus granulosus serotonin transporter 0.0296 0.1042 0.1032
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0136 0.0411 0.1128
Onchocerca volvulus 0.0121 0.0352 0.0926
Loa Loa (eye worm) hypothetical protein 0.0296 0.1042 0.1029
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0136 0.0411 0.2846
Echinococcus granulosus intermediate filament protein 0.0079 0.0185 0.0174
Brugia malayi Carm1-pending protein 0.0433 0.1584 0.3482
Plasmodium falciparum amino acid transporter, putative 0.005 0.0071 0.1106
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0106 0.0587
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0016 0.0045
Brugia malayi hypothetical protein 0.0251 0.0864 0.1889
Echinococcus granulosus ecdysone induced protein 78C 0.0041 0.0034 0.0023
Schistosoma mansoni coup transcription factor 0.0041 0.0034 0.0034
Onchocerca volvulus 0.0136 0.0411 0.1088
Trypanosoma brucei C-8 sterol isomerase, putative 0.0389 0.1409 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0041 0.0034 0.0034
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0106 0.0095
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0041 0.0034 0.002
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.005 0.0071 0.0071
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0161 0.0507 0.0495
Trypanosoma brucei proteasome beta 6 subunit 0.0069 0.0144 0.0934
Brugia malayi CXXC zinc finger family protein 0.0057 0.0096 0.0189
Echinococcus granulosus lamin dm0 0.0079 0.0185 0.0174
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.005 0.0071 0.0058
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0043 0.0041 0.0413
Loa Loa (eye worm) hypothetical protein 0.0064 0.0124 0.011
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0116 0.0102
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0136 0.0411 0.04
Schistosoma mansoni hypothetical protein 0.086 0.3269 0.3269
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0041 0.0034 0.0051
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0034 0.0034
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0016 0.0045
Onchocerca volvulus 0.0136 0.0411 0.1088
Echinococcus granulosus lysosomal alpha glucosidase 0.0161 0.0507 0.0497
Echinococcus granulosus histone arginine methyltransferase CARMER 0.0433 0.1584 0.1575
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0599 0.2238 0.6144
Brugia malayi jmjC domain containing protein 0.0064 0.0124 0.025
Trypanosoma cruzi protein arginine n-methyltransferase 7 0.0055 0.0092 0.0561
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0055 0.0092 0.0252
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.005 0.0071 0.006
Entamoeba histolytica arginine N-methyltransferase 1, putative 0.0055 0.0092 0.0364
Loa Loa (eye worm) transcription factor SMAD2 0.0237 0.0807 0.0794
Loa Loa (eye worm) hypothetical protein 0.005 0.0071 0.0058
Loa Loa (eye worm) hypothetical protein 0.0251 0.0864 0.0852
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.005 0.0071 0.0071

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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