Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tyrosine kinase | 0.0506 | 1 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0216 | 0.1312 | 0.1312 |
Schistosoma mansoni | tyrosine kinase | 0.0381 | 0.6249 | 0.5744 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0506 | 1 | 1 |
Brugia malayi | protein-tyrosine kinase | 0.0342 | 0.5063 | 0.4317 |
Brugia malayi | Sex muscle abnormal protein 5 | 0.0334 | 0.4828 | 0.4047 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0234 | 0.1849 | 0.0751 |
Loa Loa (eye worm) | sex muscle abnormal protein 5 | 0.0334 | 0.4828 | 0.4828 |
Echinococcus multilocularis | tyrosine protein kinase ABL1 | 0.0216 | 0.1312 | 0.1312 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0506 | 1 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0216 | 0.1312 | 0.1312 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0216 | 0.1312 | 0.1312 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0381 | 0.6249 | 0.6249 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0506 | 1 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0216 | 0.1312 | 0.1312 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0506 | 1 | 1 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.0234 | 0.1849 | 0.1849 |
Echinococcus granulosus | NCK adaptor protein | 0.0334 | 0.4828 | 0.4828 |
Loa Loa (eye worm) | hypothetical protein | 0.0234 | 0.1849 | 0.1849 |
Echinococcus multilocularis | growth factor receptor bound protein 2 | 0.0334 | 0.4828 | 0.4828 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0294 | 0.3641 | 0.3641 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0506 | 1 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0216 | 0.1312 | 0.1312 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0506 | 1 | 1 |
Onchocerca volvulus | 0.0216 | 0.1312 | 0.5 | |
Schistosoma mansoni | adapter molecule crk | 0.0334 | 0.4828 | 0.4132 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0334 | 0.4828 | 0.4828 |
Echinococcus multilocularis | c src tyrosine kinase | 0.0381 | 0.6249 | 0.6249 |
Brugia malayi | Variant SH3 domain containing protein | 0.0334 | 0.4828 | 0.4047 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase abl1 | 0.0334 | 0.4828 | 0.4132 |
Schistosoma mansoni | nck2/grb4 | 0.0334 | 0.4828 | 0.4132 |
Echinococcus multilocularis | tyrosine kinase | 0.0216 | 0.1312 | 0.1312 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0342 | 0.5063 | 0.5063 |
Loa Loa (eye worm) | SRC-1 | 0.0506 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0342 | 0.5063 | 0.5063 |
Schistosoma mansoni | tyrosine kinase | 0.0216 | 0.1312 | 0.0143 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0506 | 1 | 1 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0381 | 0.6249 | 0.5683 |
Loa Loa (eye worm) | hypothetical protein | 0.0334 | 0.4828 | 0.4828 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0234 | 0.1849 | 0.0751 |
Echinococcus granulosus | tyrosine kinase | 0.0216 | 0.1312 | 0.1312 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.1312 | 0.1312 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0506 | 1 | 1 |
Echinococcus granulosus | tyrosine kinase | 0.0342 | 0.5063 | 0.5063 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0234 | 0.1849 | 0.0751 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0334 | 0.4828 | 0.4132 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0381 | 0.6249 | 0.5744 |
Loa Loa (eye worm) | hypothetical protein | 0.0234 | 0.1849 | 0.1849 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0216 | 0.1312 | 0.1312 |
Onchocerca volvulus | 0.0216 | 0.1312 | 0.5 | |
Schistosoma mansoni | tyrosine kinase | 0.0381 | 0.6249 | 0.5744 |
Onchocerca volvulus | 0.0216 | 0.1312 | 0.5 | |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0334 | 0.4828 | 0.4132 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.0216 | 0.1312 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0216 | 0.1312 | 0.1312 |
Echinococcus multilocularis | tyrosine protein kinase shark | 0.0216 | 0.1312 | 0.1312 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0294 | 0.3641 | 0.3641 |
Onchocerca volvulus | 0.0216 | 0.1312 | 0.5 | |
Echinococcus multilocularis | NCK adaptor protein | 0.0334 | 0.4828 | 0.4828 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0506 | 1 | 1 |
Onchocerca volvulus | 0.0216 | 0.1312 | 0.5 | |
Loa Loa (eye worm) | TK protein kinase | 0.0342 | 0.5063 | 0.5063 |
Echinococcus granulosus | tyrosine protein kinase ABL1 | 0.0216 | 0.1312 | 0.1312 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0216 | 0.1312 | 0.1312 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0506 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0506 | 1 | 1 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0506 | 1 | 1 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0506 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0506 | 1 | 1 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0234 | 0.1849 | 0.1849 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0216 | 0.1312 | 0.1312 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0342 | 0.5063 | 0.5063 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0506 | 1 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0216 | 0.1312 | 0.1312 |
Echinococcus granulosus | tyrosine protein kinase Fps85D | 0.0216 | 0.1312 | 0.1312 |
Onchocerca volvulus | 0.0216 | 0.1312 | 0.5 | |
Echinococcus granulosus | c src tyrosine kinase | 0.0381 | 0.6249 | 0.6249 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0342 | 0.5063 | 0.5063 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0506 | 1 | 1 |
Loa Loa (eye worm) | TK/ABL protein kinase | 0.0216 | 0.1312 | 0.1312 |
Echinococcus multilocularis | tyrosine protein kinase Fps85D | 0.0216 | 0.1312 | 0.1312 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0342 | 0.5063 | 0.5063 |
Brugia malayi | Variant SH3 domain containing protein | 0.0334 | 0.4828 | 0.4047 |
Echinococcus granulosus | growth factor receptor bound protein 2 | 0.0334 | 0.4828 | 0.4828 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.0381 | 0.6249 | 0.6249 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.0381 | 0.6249 | 0.6249 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0506 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Srms | 0.0216 | 0.1312 | 0.1312 |
Echinococcus granulosus | tyrosine protein kinase shark | 0.0216 | 0.1312 | 0.1312 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0506 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0216 | 0.1312 | 0.0143 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.