Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Neurogenic locus notch protein homolog | 0.0939 | 0.2279 | 0.2278 |
Brugia malayi | Peroxidasin | 0.4095 | 1 | 1 |
Echinococcus granulosus | notch | 0.0939 | 0.2279 | 0.2278 |
Onchocerca volvulus | 0.4095 | 1 | 1 | |
Echinococcus multilocularis | slit 2 protein | 0.0939 | 0.2279 | 0.2278 |
Brugia malayi | EGF-like domain containing protein | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | animal heme peroxidase | 0.4095 | 1 | 1 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.0007 | 0.0001 | 1 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0939 | 0.2279 | 0.2278 |
Schistosoma mansoni | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Onchocerca volvulus | Peroxidasin homolog | 0.4095 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.4095 | 1 | 1 |
Schistosoma mansoni | notch | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Echinococcus multilocularis | peroxidasin | 0.4095 | 1 | 1 |
Echinococcus multilocularis | fat cadherin tumor suppressor | 0.0939 | 0.2279 | 0.2278 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0939 | 0.2279 | 0.2278 |
Brugia malayi | EGF-like domain containing protein | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Echinococcus granulosus | delta-like protein 1 | 0.0939 | 0.2279 | 0.2278 |
Echinococcus granulosus | slit 2 protein | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.4095 | 1 | 1 |
Brugia malayi | Cadherin domain containing protein | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.4095 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.4095 | 1 | 1 |
Schistosoma mansoni | peroxidasin | 0.4095 | 1 | 1 |
Schistosoma mansoni | peroxidasin | 0.4095 | 1 | 1 |
Onchocerca volvulus | 0.0939 | 0.2279 | 0.2278 | |
Schistosoma mansoni | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | IKK protein kinase | 0.1075 | 0.2613 | 0.2613 |
Schistosoma mansoni | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.4095 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Brugia malayi | Animal haem peroxidase family protein | 0.4095 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Echinococcus granulosus | protein jagged 2 | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | animal heme peroxidase | 0.4095 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Toxoplasma gondii | EGF family domain-containing protein | 0.0939 | 0.2279 | 0.5 |
Echinococcus multilocularis | protein jagged 2 | 0.0939 | 0.2279 | 0.2278 |
Onchocerca volvulus | 0.0939 | 0.2279 | 0.2278 | |
Brugia malayi | Protein kinase domain containing protein | 0.1075 | 0.2613 | 0.2613 |
Brugia malayi | Animal haem peroxidase family protein | 0.4095 | 1 | 1 |
Echinococcus granulosus | protein jagged 1 | 0.0939 | 0.2279 | 0.2278 |
Onchocerca volvulus | Neurogenic locus notch homolog | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.4095 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.4095 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.4095 | 1 | 1 |
Giardia lamblia | High cysteine protein | 0.0939 | 0.2279 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.4095 | 1 | 1 |
Echinococcus granulosus | peroxidasin | 0.4095 | 1 | 1 |
Schistosoma mansoni | notch | 0.0939 | 0.2279 | 0.2278 |
Brugia malayi | Animal haem peroxidase family protein | 0.4095 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Brugia malayi | Animal haem peroxidase family protein | 0.4095 | 1 | 1 |
Echinococcus multilocularis | neural cadherin | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.4095 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Onchocerca volvulus | Putative cubilin | 0.0939 | 0.2279 | 0.2278 |
Onchocerca volvulus | 0.1075 | 0.2613 | 0.2613 | |
Onchocerca volvulus | Dual oxidase homolog | 0.4095 | 1 | 1 |
Loa Loa (eye worm) | Notch2 | 0.0939 | 0.2279 | 0.2278 |
Echinococcus multilocularis | protein jagged 1 | 0.0939 | 0.2279 | 0.2278 |
Brugia malayi | notch-like transmembrane receptor | 0.0939 | 0.2279 | 0.2278 |
Brugia malayi | EGF-like domain containing protein | 0.0939 | 0.2279 | 0.2278 |
Brugia malayi | EGF-like domain containing protein | 0.0939 | 0.2279 | 0.2278 |
Echinococcus granulosus | fibropellin Ia | 0.0939 | 0.2279 | 0.2278 |
Schistosoma mansoni | notch | 0.0939 | 0.2279 | 0.2278 |
Schistosoma mansoni | slit | 0.0939 | 0.2279 | 0.2278 |
Schistosoma mansoni | septate junction protein | 0.0939 | 0.2279 | 0.2278 |
Schistosoma mansoni | cell polarity protein | 0.0939 | 0.2279 | 0.2278 |
Echinococcus multilocularis | neurogenic locus notch protein 4 | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.4095 | 1 | 1 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.4095 | 1 | 1 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0939 | 0.2279 | 0.2278 |
Schistosoma mansoni | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.4095 | 1 | 1 |
Echinococcus granulosus | protein jagged 2 | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Brugia malayi | Animal haem peroxidase family protein | 0.4095 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Brugia malayi | EGF-like domain containing protein | 0.0939 | 0.2279 | 0.2278 |
Onchocerca volvulus | 0.4095 | 1 | 1 | |
Echinococcus granulosus | neurogenic locus notch protein 4 | 0.0939 | 0.2279 | 0.2278 |
Schistosoma mansoni | notch | 0.0939 | 0.2279 | 0.2278 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0008 | 0.0004 | 0.0003 |
Brugia malayi | EGF-like domain containing protein | 0.0939 | 0.2279 | 0.2278 |
Schistosoma mansoni | notch | 0.0939 | 0.2279 | 0.2278 |
Onchocerca volvulus | 0.0939 | 0.2279 | 0.2278 | |
Onchocerca volvulus | 0.0939 | 0.2279 | 0.2278 | |
Onchocerca volvulus | Peroxidasin homolog | 0.4095 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Echinococcus granulosus | neural cadherin | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.4095 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Onchocerca volvulus | Peroxidase homolog | 0.4095 | 1 | 1 |
Brugia malayi | Blistered cuticle protein 3 | 0.4095 | 1 | 1 |
Echinococcus granulosus | neurogenic locus protein delta | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.4095 | 1 | 1 |
Echinococcus multilocularis | notch | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Onchocerca volvulus | 0.4095 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.4095 | 1 | 1 |
Brugia malayi | Transmembrane cell adhesion receptor mua-3 precursor, putative | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.4095 | 1 | 1 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Schistosoma mansoni | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Schistosoma mansoni | Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] | 0.0939 | 0.2279 | 0.2278 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0939 | 0.2279 | 0.2278 |
Echinococcus multilocularis | protein jagged 1 | 0.0939 | 0.2279 | 0.2278 |
Onchocerca volvulus | 0.0939 | 0.2279 | 0.2278 | |
Onchocerca volvulus | Peroxidase homolog | 0.4095 | 1 | 1 |
Echinococcus granulosus | protein jagged 1 | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0939 | 0.2279 | 0.2278 |
Onchocerca volvulus | Slit protein homolog | 0.0939 | 0.2279 | 0.2278 |
Brugia malayi | Delta serrate ligand family protein | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | notch protein | 0.0939 | 0.2279 | 0.2278 |
Brugia malayi | Muscle positioning protein 4 | 0.0939 | 0.2279 | 0.2278 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0939 | 0.2279 | 0.2278 |
Brugia malayi | EGF-like domain containing protein | 0.0939 | 0.2279 | 0.2278 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | animal heme peroxidase | 0.4095 | 1 | 1 |
Echinococcus multilocularis | fibropellin Ia | 0.0939 | 0.2279 | 0.2278 |
Loa Loa (eye worm) | hypothetical protein | 0.0939 | 0.2279 | 0.2278 |
Schistosoma mansoni | notch | 0.0939 | 0.2279 | 0.2278 |
Brugia malayi | Cadherin domain containing protein | 0.0939 | 0.2279 | 0.2278 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.