Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Bos taurus | Adenosine deaminase | Starlite/ChEMBL | References |
Species | Potential target | Known druggable target | Length | Alignment span | Identity |
---|---|---|---|---|---|
Dictyostelium discoideum | adenosine deaminase-related growth factor | Adenosine deaminase | 363 aa | 299 aa | 25.8 % |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | AMP deaminase, putative | 0.0034 | 0 | 0.5 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0104 | 1 | 1 |
Plasmodium vivax | adenosine deaminase, putative | 0.0104 | 1 | 1 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0104 | 1 | 0.5 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0034 | 0 | 0.5 |
Echinococcus granulosus | adenosine deaminase | 0.0104 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 1 | 1 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0104 | 1 | 1 |
Schistosoma mansoni | adenosine deaminase | 0.0104 | 1 | 1 |
Schistosoma mansoni | adenosine deaminase-related | 0.0104 | 1 | 1 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0104 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0081 | 0.6746 | 0.6746 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0034 | 0 | 0.5 |
Mycobacterium ulcerans | adenosine deaminase | 0.0104 | 1 | 0.5 |
Trypanosoma cruzi | adenosine monophosphate deaminase, putative | 0.0034 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.5169 | 0.5169 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.5169 | 0.5169 |
Leishmania major | adenine aminohydrolase | 0.0104 | 1 | 1 |
Onchocerca volvulus | Adenosine deaminase homolog | 0.0104 | 1 | 1 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0104 | 1 | 0.5 |
Plasmodium falciparum | adenosine deaminase | 0.0104 | 1 | 1 |
Mycobacterium tuberculosis | Probable adenosine deaminase Add (adenosine aminohydrolase) | 0.0104 | 1 | 0.5 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0104 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.5169 | 0.5169 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0034 | 0 | 0.5 |
Trypanosoma cruzi | AMP deaminase 2, putative | 0.0034 | 0 | 0.5 |
Trypanosoma brucei | RNA helicase, putative | 0.0081 | 0.6746 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.5169 | 0.5169 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0034 | 0 | 0.5 |
Echinococcus multilocularis | adenosine deaminase | 0.0104 | 1 | 1 |
Mycobacterium leprae | Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) | 0.0104 | 1 | 0.5 |
Treponema pallidum | adenosine deaminase | 0.0104 | 1 | 0.5 |
Trypanosoma cruzi | adenosine monophosphate deaminase-like protein, putative | 0.0034 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.