Detailed information for compound 1744692

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 741.56 | Formula: C22H46N7O15P3
  • H donors: 9 H acceptors: 12 LogP: -8.35 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 4
  • SMILES: O[C@H]1[C@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@@H]([C@H]1O)n1cnc2c1c(=O)[nH][nH]c(=O)[nH]2.CCN(CC)CC.CCN(CC)CC
  • InChi: 1S/C10H16N5O15P3.2C6H15N/c16-5-3(1-27-32(23,24)30-33(25,26)29-31(20,21)22)28-9(6(5)17)15-2-11-7-4(15)8(18)13-14-10(19)12-7;2*1-4-7(5-2)6-3/h2-3,5-6,9,16-17H,1H2,(H,13,18)(H,23,24)(H,25,26)(H2,12,14,19)(H2,20,21,22);2*4-6H2,1-3H3/t3-,5-,6-,9-;;/m0../s1
  • InChiKey: HEMZXRUKJCLZJP-KOAXJDANSA-N  

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Hepatitis C virus Hepatitis C virus NS3 protease/helicase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Neospora caninum DEAD-box ATP-dependent RNA helicase 34 (EC 3.6.1.-), related Get druggable targets OG5_126984 All targets in OG5_126984
Trypanosoma brucei gambiense eukaryotic initiation factor 4a, putative Get druggable targets OG5_126984 All targets in OG5_126984
Leishmania major eukaryotic initiation factor 4a, putative Get druggable targets OG5_126984 All targets in OG5_126984
Leishmania major eukaryotic initiation factor 4a, putative Get druggable targets OG5_126984 All targets in OG5_126984
Theileria parva RNA helicase-1, putative Get druggable targets OG5_126984 All targets in OG5_126984
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) Get druggable targets OG5_126984 All targets in OG5_126984
Schistosoma japonicum ATP-dependent RNA helicase eIF4A, putative Get druggable targets OG5_126984 All targets in OG5_126984
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126984 All targets in OG5_126984
Brugia malayi eukaryotic initiation factor 4A Get druggable targets OG5_126984 All targets in OG5_126984
Echinococcus multilocularis eukaryotic initiation factor 4A Get druggable targets OG5_126984 All targets in OG5_126984
Onchocerca volvulus Eukaryotic initiation factor 4A homolog Get druggable targets OG5_126984 All targets in OG5_126984
Entamoeba histolytica DEAD/DEAH box helicase, putative Get druggable targets OG5_126984 All targets in OG5_126984
Leishmania infantum eukaryotic initiation factor 4a, putative Get druggable targets OG5_126984 All targets in OG5_126984
Leishmania infantum eukaryotic initiation factor 4a, putative Get druggable targets OG5_126984 All targets in OG5_126984
Trypanosoma congolense eukaryotic initiation factor 4a, putative Get druggable targets OG5_126984 All targets in OG5_126984
Toxoplasma gondii eukaryotic initiation factor-4A, putative Get druggable targets OG5_126984 All targets in OG5_126984
Cryptosporidium parvum eukaryotic initiation factor 4A (eIF4A) (eIF-4A) Get druggable targets OG5_126984 All targets in OG5_126984
Schistosoma japonicum Eukaryotic initiation factor 4A-III, putative Get druggable targets OG5_126984 All targets in OG5_126984
Echinococcus granulosus eukaryotic initiation factor 4A III Get druggable targets OG5_126984 All targets in OG5_126984
Candida albicans similar to S. cerevisiae TIF1 (YKR059W) and TIF2 (YJL138C) translation initiation factor eIF4A subunit Get druggable targets OG5_126984 All targets in OG5_126984
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 Get druggable targets OG5_126984 All targets in OG5_126984
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative Get druggable targets OG5_126984 All targets in OG5_126984
Leishmania braziliensis eukaryotic initiation factor 4a, putative Get druggable targets OG5_126984 All targets in OG5_126984
Schistosoma mansoni DEAD box ATP-dependent RNA helicase Get druggable targets OG5_126984 All targets in OG5_126984
Cryptosporidium hominis eukaryotic initiation factor 4A (eIF4A) (eIF-4A) Get druggable targets OG5_126984 All targets in OG5_126984
Plasmodium vivax RNA helicase-1, putative Get druggable targets OG5_126984 All targets in OG5_126984
Schistosoma mansoni DEAD box ATP-dependent RNA helicase Get druggable targets OG5_126984 All targets in OG5_126984
Plasmodium knowlesi eukaryotic initiation factor 4a, putative Get druggable targets OG5_126984 All targets in OG5_126984
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 Get druggable targets OG5_126984 All targets in OG5_126984
Leishmania mexicana Get druggable targets OG5_126984 All targets in OG5_126984
Babesia bovis eukaryotic translation initiation factor 4A, putative Get druggable targets OG5_126984 All targets in OG5_126984
Giardia lamblia Translation initiation factor eIF-4A, putative Get druggable targets OG5_126984 All targets in OG5_126984
Echinococcus granulosus eukaryotic initiation factor 4A Get druggable targets OG5_126984 All targets in OG5_126984
Plasmodium falciparum eukaryotic initiation factor 4A Get druggable targets OG5_126984 All targets in OG5_126984
Treponema pallidum ATP-dependent RNA helicase Get druggable targets OG5_126984 All targets in OG5_126984
Plasmodium berghei eukaryotic initiation factor 4a, putative Get druggable targets OG5_126984 All targets in OG5_126984
Plasmodium yoelii RNA helicase-1 Get druggable targets OG5_126984 All targets in OG5_126984
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative Get druggable targets OG5_126984 All targets in OG5_126984
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative Get druggable targets OG5_126984 All targets in OG5_126984
Schistosoma japonicum Eukaryotic initiation factor 4A-II, putative Get druggable targets OG5_126984 All targets in OG5_126984
Echinococcus multilocularis eukaryotic initiation factor 4A III Get druggable targets OG5_126984 All targets in OG5_126984
Leishmania donovani Eukaryotic initiation factor 4A-1 Get druggable targets OG5_126984 All targets in OG5_126984
Trypanosoma brucei Eukaryotic initiation factor 4A-1 Get druggable targets OG5_126984 All targets in OG5_126984
Candida albicans similar to S. cerevisiae TIF1 (YKR059W) and TIF2 (YJL138C) translation initiation factor eIF4A subunit Get druggable targets OG5_126984 All targets in OG5_126984

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis Glutaredoxin protein 5 0.0119 0.0169 0.0169
Brugia malayi EGF-like domain containing protein 0.029 0.078 0.0769
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Trypanosoma cruzi NADH dehydrogenase, putative 0.0264 0.0687 0.0683
Echinococcus multilocularis cyclin 0.0712 0.2287 0.2287
Loa Loa (eye worm) thyroid receptor interactor 0.011 0.0136 0.0125
Schistosoma mansoni nephrin related 0.0126 0.0194 0.0194
Mycobacterium tuberculosis Probable oxidoreductase 0.0994 0.3298 0.2803
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0154 0.0295 0.0295
Brugia malayi Protein kinase domain containing protein 0.0098 0.0094 0.0083
Onchocerca volvulus 0.0098 0.0094 0.0549
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0065 0.0087
Schistosoma mansoni nephrin 0.0634 0.2009 0.2009
Giardia lamblia Kinase, PLK 0.0264 0.0686 0.1978
Giardia lamblia Kinase, CMGC MAPK 0.0084 0.0044 0.0007
Echinococcus granulosus casein kinase ii subunit alpha 0.01 0.0101 0.0101
Brugia malayi Protein kinase domain containing protein 0.0343 0.0969 0.0959
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0084 0.0044 0.001
Schistosoma mansoni cell adhesion molecule 0.0293 0.0791 0.0791
Echinococcus multilocularis roundabout 2 0.0786 0.2552 0.2552
Echinococcus granulosus aurora kinase A 0.0144 0.0257 0.0257
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0151 0.0285 0.0281
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0991 0.3286 0.3279
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0144 0.0257 0.1105
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0088 0.0056 0.0242
Echinococcus granulosus tyrosine kinase 0.0183 0.0397 0.0397
Trypanosoma brucei protein kinase, putative 0.0127 0.0199 0.0165
Echinococcus granulosus NCK adaptor protein 0.0089 0.0061 0.0061
Trichomonas vaginalis AGC family protein kinase 0.0185 0.0404 0.1128
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0421 0.1249 0.1249
Echinococcus granulosus dual specificity 0.0137 0.0234 0.0234
Echinococcus granulosus neurogenic locus notch protein 0.029 0.078 0.078
Loa Loa (eye worm) hypothetical protein 0.0344 0.0974 0.0964
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0293 0.0791 0.0791
Brugia malayi MH2 domain containing protein 0.0132 0.0214 0.0202
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0165 0.0334 0.0334
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0686 0.1992
Echinococcus multilocularis slit 2 protein 0.0317 0.0878 0.0878
Echinococcus granulosus Immunoglobulin 0.0152 0.0287 0.0287
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0453 0.0453
Echinococcus multilocularis notch 0.029 0.078 0.078
Brugia malayi Temporarily assigned gene name protein 59 0.0124 0.0187 0.0176
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0264 0.0687 0.0676
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0264 0.0687 0.1994
Echinococcus multilocularis rac serine:threonine kinase 0.0163 0.0326 0.0326
Loa Loa (eye worm) hypothetical protein 0.0108 0.0128 0.0117
Plasmodium vivax glycogen synthase kinase 3, putative 0.0127 0.0199 0.0165
Echinococcus granulosus low density lipoprotein receptor ldl 0.0152 0.0287 0.0287
Echinococcus granulosus insulin receptor 0.0433 0.1292 0.1292
Brugia malayi P38 map kinase family protein 2 0.0157 0.0304 0.0293
Brugia malayi cyclin-dependent kinase 9 0.0079 0.0026 0.0015
Entamoeba histolytica PH domain containing protein kinase, putative 0.0163 0.0326 0.1402
Brugia malayi Immunoglobulin I-set domain containing protein 0.0167 0.034 0.0329
Entamoeba histolytica protein kinase domain containing protein 0.0199 0.0453 0.1951
Brugia malayi casein kinase I 0.0108 0.013 0.0119
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0212 0.0503 0.0493
Brugia malayi Sushi domain 0.0535 0.1657 0.1647
Trypanosoma cruzi Protein kinase B 0.0163 0.0326 0.0322
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0127 0.0199 0.0189
Brugia malayi Immunoglobulin I-set domain containing protein 0.0278 0.0738 0.0727
Brugia malayi Leucine Rich Repeat family protein 0.0126 0.0195 0.0184
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0121 0.0177 0.0143
Schistosoma mansoni hypothetical protein 0.0098 0.0094 0.0094
Schistosoma mansoni tyrosine kinase 0.0343 0.0971 0.0971
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0172 0.0359 0.0359
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0101 0.0103 0.0069
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0112 0.0145 0.0142
Brugia malayi Protein kinase domain containing protein 0.0277 0.0733 0.0722
Loa Loa (eye worm) hypothetical protein 0.0507 0.1558 0.1549
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0152 0.0287 0.0287
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0389 0.1136 0.1136
Brugia malayi Protein kinase domain containing protein 0.0433 0.1292 0.1282
Echinococcus multilocularis titin 0.0126 0.0194 0.0194
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0194 0.0183
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0194 0.0183
Schistosoma mansoni tyrosine kinase 0.0135 0.0226 0.0226
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0145 0.0145
Loa Loa (eye worm) gastrulation defective protein 1 0.0906 0.2984 0.2977
Loa Loa (eye worm) hypothetical protein 0.0137 0.0235 0.0224
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0994 0.3298 0.3275
Leishmania major casein kinase, putative 0.0108 0.013 0.0096
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0234 0.0607
Toxoplasma gondii casein kinase I 0.0108 0.013 0.0096
Schistosoma mansoni serine/threonine protein kinase 0.0079 0.0026 0.0026
Echinococcus multilocularis insulin growth factor binding 0.0126 0.0194 0.0194
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0185 0.0404 0.0394
Echinococcus multilocularis myosin iiia 0.0085 0.0048 0.0048
Brugia malayi Immunoglobulin I-set domain containing protein 0.0152 0.0287 0.0275
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Toxoplasma gondii histone kinase SNF1, putative 0.009 0.0064 0.003
Plasmodium falciparum calcium-dependent protein kinase 2 0.0101 0.0103 0.0069
Brugia malayi Delta serrate ligand family protein 0.029 0.078 0.0769
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0994 0.3298 0.3275
Echinococcus multilocularis dual specificity 0.0137 0.0234 0.0234
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0234 0.0607
Onchocerca volvulus 0.0535 0.1657 1
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0101 0.0103 0.0068
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0152 0.0287 0.0276
Brugia malayi Protein kinase domain containing protein 0.0197 0.0447 0.0436
Echinococcus multilocularis expressed conserved protein 0.0133 0.0219 0.0219
Echinococcus multilocularis protein jagged 2 0.029 0.078 0.078
Plasmodium falciparum cGMP-dependent protein kinase 0.0133 0.0219 0.0186
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0112 0.0145 0.0111
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0151 0.0283 0.0273
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0154 0.0295 0.0262
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0237 0.059 0.059
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0133 0.0219 0.0219
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0089 0.0061 0.0051
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0264 0.0687 0.0687
Schistosoma mansoni tyrosine kinase 0.0304 0.0829 0.0829
Entamoeba histolytica PH domain containing protein kinase, putative 0.0121 0.0176 0.0757
Echinococcus granulosus dual specificity 0.0121 0.0177 0.0177
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0448 0.1346 0.1346
Brugia malayi Disorganized muscle protein 1 0.0126 0.0194 0.0183
Schistosoma mansoni serine/threonine protein kinase 0.0942 0.3111 0.3111
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0089 0.0061 0.0051
Brugia malayi Protein kinase domain containing protein 0.0435 0.1299 0.1289
Plasmodium falciparum calcium-dependent protein kinase 3 0.0101 0.0103 0.0069
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0264 0.0687 0.0683
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0126 0.0194 0.0184
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0183 0.0397 0.0397
Plasmodium falciparum protein serine/threonine kinase-1 0.0151 0.0285 0.0252
Loa Loa (eye worm) hypothetical protein 0.0507 0.1558 0.1549
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0101 0.0197
Entamoeba histolytica protein kinase, putative 0.0284 0.076 0.3268
Brugia malayi Immunoglobulin I-set domain containing protein 0.0154 0.0293 0.0281
Schistosoma mansoni microtubule-associated protein tau 0.0761 0.2463 0.2463
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0264 0.0687 0.1853
Schistosoma mansoni hypothetical protein 0.029 0.078 0.078
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0085 0.0048 0.0013
Onchocerca volvulus 0.029 0.078 0.4693
Schistosoma mansoni serine/threonine protein kinase 0.0212 0.0499 0.0499
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0334 0.0334
Schistosoma mansoni tyrosine kinase 0.0533 0.1649 0.1649
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0258 0.0665 0.0656
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0144 0.0257 0.0257
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0101 0.0197
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0994 0.3298 0.3298
Onchocerca volvulus 0.0126 0.0194 0.1152
Brugia malayi Immunoglobulin I-set domain containing protein 0.0293 0.0791 0.0781
Echinococcus multilocularis raf serine:threonine protein kinase 0.0086 0.0052 0.0052
Brugia malayi Protein kinase domain containing protein 0.0151 0.0285 0.0274
Entamoeba histolytica protein kinase, putative 0.0101 0.0103 0.0444
Echinococcus multilocularis 0.0126 0.0194 0.0194
Echinococcus multilocularis cyclin dependent kinase 0.0118 0.0165 0.0165
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0264 0.0687 0.0655
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0257 0.0675
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0165 0.0334 0.0334
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0619 0.0619
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0189 0.042 0.041
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0257 0.0675
Loa Loa (eye worm) hypothetical protein 0.0134 0.0221 0.021
Brugia malayi phosphoinositide-dependent protein kinase I 0.0082 0.0037 0.0025
Leishmania major hypothetical protein, conserved 0.0264 0.0687 0.0655
Plasmodium falciparum casein kinase 1 0.0108 0.013 0.0096
Entamoeba histolytica protein kinase, putative 0.0074 0.0008 0.0036
Schistosoma mansoni glutamate synthase 0.0264 0.0687 0.0687
Echinococcus granulosus rho-associated protein kinase 1 0.0317 0.0875 0.0875
Trypanosoma cruzi cdc2-related kinase 3 0.0118 0.0165 0.0161
Brugia malayi Myb-like DNA-binding domain containing protein 0.0126 0.0194 0.0183
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Entamoeba histolytica protein kinase domain containing protein 0.0081 0.0034 0.0147
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0994 0.3298 1
Giardia lamblia NADH oxidase lateral transfer candidate 0.0994 0.3298 1
Brugia malayi hypothetical protein 0.0535 0.1657 0.1647
Echinococcus multilocularis fat cadherin tumor suppressor 0.029 0.078 0.078
Giardia lamblia Kinase, CK1 Casein kinase 0.0108 0.013 0.027
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0994 0.3298 0.3295
Loa Loa (eye worm) hypothetical protein 0.02 0.0459 0.0449
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0994 0.3298 0.3275
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0285 0.0285
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0343 0.0969 0.096
Trypanosoma cruzi casein kinase, putative 0.0108 0.013 0.0126
Entamoeba histolytica casein kinase 1, putative 0.0108 0.013 0.056
Entamoeba histolytica protein kinase 2, putative 0.0154 0.0295 0.127
Trichomonas vaginalis AGC family protein kinase 0.0173 0.0362 0.0996
Brugia malayi Prion-like- 0.0278 0.0738 0.0727
Onchocerca volvulus 0.03 0.0818 0.4923
Loa Loa (eye worm) protein kinase domain-containing protein 0.0209 0.049 0.048
Schistosoma mansoni protein kinase 0.0259 0.0668 0.0668
Echinococcus granulosus dual specificity 0.0137 0.0234 0.0234
Schistosoma mansoni tyrosine kinase 0.0433 0.1292 0.1292
Toxoplasma gondii aurora kinase 0.0144 0.0257 0.0223
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0535 0.1657 0.1648
Giardia lamblia Kinase, NEK 0.0135 0.0225 0.0561
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0143 0.0255 0.0255
Echinococcus multilocularis serine:threonine protein kinase N2 0.0125 0.0189 0.0189
Brugia malayi Cyclin C 0.1427 0.4846 0.484
Plasmodium falciparum calcium-dependent protein kinase 5 0.0101 0.0103 0.0069
Brugia malayi Protein kinase domain containing protein 0.0162 0.0321 0.031
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0581 0.1821 0.1812
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Loa Loa (eye worm) hypothetical protein 0.0178 0.0379 0.0368
Echinococcus granulosus tyrosine protein kinase Fyn 0.022 0.0528 0.0528
Onchocerca volvulus 0.0177 0.0375 0.2243
Onchocerca volvulus 0.0126 0.0194 0.1152
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0133 0.0219 0.0186
Loa Loa (eye worm) AUR protein kinase 0.0144 0.0257 0.0247
Schistosoma mansoni adapter molecule crk 0.0089 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0535 0.1657 0.1648
Giardia lamblia Kinase, CAMK CAMKL 0.0097 0.0091 0.0151
Schistosoma mansoni protein kinase 0.0357 0.1018 0.1018
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0112 0.0145 0.0111
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0994 0.3298 0.3275
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0994 0.3298 0.3275
Echinococcus granulosus dual specificity 0.0137 0.0234 0.0234
Schistosoma mansoni hypothetical protein 0.029 0.078 0.078
Schistosoma mansoni protein kinase 0.0421 0.1249 0.1249
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0157 0.0304 0.027
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0194 0.0183
Echinococcus granulosus protein jagged 1 0.029 0.078 0.078
Brugia malayi Peroxidasin 0.0278 0.0739 0.0728
Loa Loa (eye worm) hypothetical protein 0.0535 0.1657 0.1648
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0234 0.0607
Schistosoma mansoni serine/threonine protein kinase 0.029 0.078 0.078
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Onchocerca volvulus 0.0074 0.0008 0.0025
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0264 0.0687 0.0655
Brugia malayi Immunoglobulin I-set domain containing protein 0.0507 0.1558 0.1548
Loa Loa (eye worm) SRC-1 0.022 0.0528 0.0518
Loa Loa (eye worm) TK protein kinase 0.0363 0.1041 0.1031
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0152 0.0355
Echinococcus multilocularis G protein coupled receptor 139 0.079 0.2567 0.2567
Trypanosoma brucei Casein kinase II 0.01 0.0101 0.0067
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0264 0.0687 0.1994
Trypanosoma brucei casein kinase I, isoform 2 0.0108 0.013 0.0096
Loa Loa (eye worm) casein kinase 0.0173 0.0363 0.0353
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0084 0.0042 0.0008
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0199 0.0453 0.0442
Loa Loa (eye worm) hypothetical protein 0.0114 0.0153 0.0142
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0246 0.0623 0.0623
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0357 0.1018 0.1018
Echinococcus granulosus titin 0.0126 0.0194 0.0194
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0094 0.0084
Schistosoma mansoni tyrosine kinase 0.0324 0.0902 0.0902
Echinococcus multilocularis mitogen activated protein kinase 3 0.0084 0.0044 0.0044
Echinococcus multilocularis CDC7 cell division cycle 7 0.009 0.0065 0.0065
Schistosoma mansoni vav2 0.0101 0.0105 0.0105
Schistosoma mansoni hypothetical protein 0.029 0.078 0.078
Onchocerca volvulus 0.029 0.078 0.4693
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0112 0.0145 0.0134
Schistosoma mansoni ste20-related kinase 0.0201 0.0462 0.0462
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0108 0.0128 0.0128
Echinococcus granulosus down syndrome cell adhesion 0.0126 0.0194 0.0194
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0167 0.034 0.034
Echinococcus multilocularis 0.0167 0.0341 0.0341
Loa Loa (eye worm) AGC/PKG protein kinase 0.0133 0.0219 0.0209
Schistosoma mansoni slit 0.029 0.0781 0.0781
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0213 0.0505 0.0495
Schistosoma mansoni titin 0.0126 0.0194 0.0194
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0285 0.0285
Echinococcus granulosus notch 0.029 0.078 0.078
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0686 0.1992
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0234 0.0607
Trichomonas vaginalis CAMK family protein kinase 0.0212 0.0503 0.143
Trypanosoma cruzi polo-like protein kinase, putative 0.0264 0.0686 0.0683
Entamoeba histolytica protein kinase, putative 0.0137 0.0234 0.1009
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0197 0.0447 0.0447
Trichomonas vaginalis CMGC family protein kinase 0.0151 0.0285 0.0761
Echinococcus granulosus protein kinase 0.0151 0.0283 0.0283
Echinococcus multilocularis neurogenic locus notch protein 4 0.029 0.078 0.078
Loa Loa (eye worm) hypothetical protein 0.0293 0.0791 0.0782
Echinococcus granulosus nephrin 0.0141 0.0248 0.0248
Onchocerca volvulus 0.0098 0.0094 0.0549
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0097 0.0091 0.0056
Toxoplasma gondii EGF family domain-containing protein 0.029 0.078 0.0748
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0118 0.0165 0.0131
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0293 0.0791 0.0791
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0165 0.0394
Brugia malayi probable protein kinase 0.0259 0.0668 0.0657
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0112 0.0145 0.0142
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0157 0.0304 0.027
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0118 0.0165 0.0165
Entamoeba histolytica casein kinase, putative 0.0108 0.013 0.056
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0151 0.0285 0.0281
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0108 0.013 0.012
Trichomonas vaginalis glutamate synthase, putative 0.0264 0.0687 0.1994
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Loa Loa (eye worm) MH2 domain-containing protein 0.0132 0.0214 0.0203
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.015 0.0278 0.074
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0264 0.0687 0.0687
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0581 0.1821 0.1812
Brugia malayi Temporarily assigned gene name protein 59 0.0108 0.0128 0.0116
Brugia malayi EGF-like domain containing protein 0.029 0.078 0.0769
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0712 0.2287 0.2287
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0147 0.0147
Onchocerca volvulus 0.0126 0.0194 0.1152
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0237 0.059 0.059
Echinococcus granulosus fibropellin Ia 0.029 0.078 0.078
Echinococcus multilocularis dual specificity 0.0121 0.0177 0.0177
Brugia malayi Heparan sulfate 0.0152 0.0287 0.0275
Loa Loa (eye worm) hypothetical protein 0.0137 0.0235 0.0224
Trichomonas vaginalis STE family protein kinase 0.0086 0.0052 0.0048
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0152 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Echinococcus granulosus NDR protein kinase 0.0165 0.0334 0.0334
Onchocerca volvulus Putative cubilin 0.029 0.078 0.4693
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0686 0.1992
Loa Loa (eye worm) hypothetical protein 0.0078 0.0024 0.0013
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Echinococcus granulosus neuroglian 0.0619 0.1955 0.1955
Schistosoma mansoni tyrosine kinase 0.0343 0.0971 0.0971
Toxoplasma gondii selenide, water dikinase 0.0264 0.0687 0.0655
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0108 0.0128 0.0094
Brugia malayi Prion-like- 0.0126 0.0194 0.0183
Schistosoma mansoni kinase 0.0281 0.075 0.075
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0152 0.0287 0.0287
Schistosoma mansoni peroxidasin 0.0152 0.0288 0.0288
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0126 0.0194 0.0183
Brugia malayi Doublecortin family protein 0.0149 0.0275 0.0264
Schistosoma mansoni titin 0.0126 0.0194 0.0194
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0213 0.0505 0.0494
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0264 0.0687 0.0687
Schistosoma mansoni protein kinase 0.0086 0.0052 0.0052
Echinococcus granulosus growth factor receptor bound protein 2 0.0091 0.0068 0.0068
Schistosoma mansoni kinase 0.0079 0.0026 0.0026
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0157 0.0304 0.0294
Echinococcus granulosus neurogenic locus protein delta 0.029 0.078 0.078
Entamoeba histolytica protein kinase, putative 0.0088 0.0056 0.0242
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0264 0.0686 0.0654
Echinococcus multilocularis neuropeptide receptor 0.079 0.2567 0.2567
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0278 0.0738 0.0728
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0092 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0299 0.0812 0.0802
Loa Loa (eye worm) hypothetical protein 0.0492 0.1504 0.1495
Echinococcus multilocularis roundabout 2 0.0293 0.0791 0.0791
Trypanosoma cruzi casein kinase II, putative 0.01 0.0101 0.0097
Echinococcus granulosus cyclin dependent kinase 5 0.0118 0.0165 0.0165
Loa Loa (eye worm) TK/EPH protein kinase 0.0125 0.0188 0.0178
Echinococcus granulosus tyrosine protein kinase Lyn 0.0255 0.0655 0.0655
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0127 0.0199 0.0165
Brugia malayi Protein kinase domain containing protein 0.091 0.2997 0.2989
Trypanosoma cruzi cdc2-related kinase 1 0.0118 0.0165 0.0161
Loa Loa (eye worm) hypothetical protein 0.0771 0.2498 0.249
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0149 0.0275 0.0265
Brugia malayi hypothetical protein 0.0535 0.1657 0.1647
Leishmania major protein kinase, putative 0.0151 0.0285 0.0252
Mycobacterium ulcerans glutamate synthase subunit beta 0.0264 0.0687 0.1853
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.01 0.0101 0.0066
Schistosoma mansoni tyrosine kinase 0.059 0.1852 0.1852
Loa Loa (eye worm) hypothetical protein 0.0141 0.0248 0.0238
Loa Loa (eye worm) hypothetical protein 0.0278 0.0738 0.0728
Leishmania major trypanothione reductase 0.2869 1 1
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0077 0.0019 0.0019
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0264 0.0687 0.0683
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0121 0.0177 0.0173
Brugia malayi Immunoglobulin I-set domain containing protein 0.0278 0.0738 0.0727
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0151 0.0285 0.0252
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0151 0.0285 0.0281
Echinococcus multilocularis neurogenic locus protein delta 0.029 0.078 0.078
Schistosoma mansoni tyrosine kinase 0.0076 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0344 0.0974 0.0964
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0392 0.1143 0.1143
Loa Loa (eye worm) TK/INSR protein kinase 0.0433 0.1292 0.1283
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Brugia malayi Tyrosine-protein kinase abl-1 0.0135 0.0226 0.0214
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0177 0.0375 0.0364
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0293 0.0791 0.0791
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0127 0.0199 0.0199
Echinococcus multilocularis activin receptor type 0.0081 0.0034 0.0034
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0144 0.0257 0.1105
Onchocerca volvulus 0.0535 0.1657 1
Loa Loa (eye worm) cyclin C 0.1427 0.4846 0.484
Entamoeba histolytica protein kinase, putative 0.0121 0.0177 0.0761
Echinococcus granulosus nervana 2 0.0119 0.0169 0.0169
Trypanosoma cruzi casein kinase, putative 0.0108 0.013 0.0126
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0082 0.0037 0.0037
Schistosoma mansoni vesicular amine transporter 0.0492 0.1504 0.1504
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Brugia malayi basement membrane proteoglycan precursor 0.0152 0.0287 0.0275
Echinococcus multilocularis casein kinase I delta 0.0108 0.013 0.013
Onchocerca volvulus 0.0178 0.0379 0.2267
Echinococcus granulosus peroxidasin 0.0278 0.0739 0.0739
Schistosoma mansoni glutamate synthase 0.0264 0.0687 0.0687
Echinococcus granulosus tyrosine protein kinase Fyn 0.022 0.0528 0.0528
Echinococcus granulosus casein kinase I alpha 0.0108 0.013 0.013
Plasmodium falciparum casein kinase 2, alpha subunit 0.01 0.0101 0.0067
Leishmania major casein kinase II, putative 0.01 0.0101 0.0067
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0152 0.0287 0.0287
Entamoeba histolytica protein kinase domain containing protein 0.0121 0.0177 0.0761
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0278 0.0738 0.4439
Trypanosoma brucei polo-like protein kinase 0.0264 0.0686 0.0654
Echinococcus granulosus insulin growth factor binding 0.0126 0.0194 0.0194
Plasmodium falciparum protein kinase 5 0.0118 0.0165 0.0131
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0293 0.0791 0.0791
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.013 0.013
Brugia malayi SH2 domain containing protein 0.039 0.1138 0.1128
Brugia malayi RhoGAP domain containing protein 0.0092 0.0074 0.0062
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0264 0.0687 0.0687
Leishmania major protein kinase, putative 0.0151 0.0285 0.0252
Echinococcus granulosus tyrosine protein kinase Src64B 0.022 0.0528 0.0528
Schistosoma mansoni serine/threonine-protein kinase 0.0163 0.0326 0.0326
Echinococcus multilocularis casein kinase I delta 0.0108 0.013 0.013
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0264 0.0687 0.0683
Loa Loa (eye worm) AGC/NDR protein kinase 0.0165 0.0334 0.0324
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0081 0.0034 0.0031
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0137 0.0234 0.0223
Echinococcus granulosus mitogen activated protein kinase 14 0.0157 0.0304 0.0304
Echinococcus multilocularis nervana 2 0.0119 0.0169 0.0169
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0264 0.0687 0.1853
Echinococcus granulosus titin 0.0126 0.0194 0.0194
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0137 0.0234 0.0201
Trypanosoma cruzi hypothetical protein, conserved 0.0264 0.0687 0.0683
Onchocerca volvulus 0.0317 0.0875 0.527
Echinococcus multilocularis casein kinase ii subunit alpha 0.01 0.0101 0.0101
Schistosoma mansoni myosin-binding protein-related 0.0141 0.0248 0.0248
Schistosoma mansoni hypothetical protein 0.0152 0.0287 0.0287
Brugia malayi STE20-like kinase MST 0.0251 0.064 0.0629
Entamoeba histolytica hypothetical protein 0.0121 0.0177 0.0761
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Brugia malayi Prion-like- 0.0126 0.0194 0.0183
Echinococcus multilocularis serine threonine protein kinase 0.0205 0.0475 0.0475
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0183 0.0397 0.0397
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0264 0.0687 0.0676
Echinococcus multilocularis neuroglian 0.0619 0.1955 0.1955
Schistosoma mansoni tyrosine kinase 0.022 0.0528 0.0528
Schistosoma mansoni laminin gamma-3 chain 0.029 0.078 0.078
Echinococcus granulosus expressed protein 0.0084 0.0042 0.0042
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0264 0.0687 0.0655
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0152 0.0355
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0321 0.0889 0.0879
Echinococcus granulosus protein jagged 2 0.029 0.078 0.078
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0135 0.0225 0.019
Toxoplasma gondii AGC kinase 0.0112 0.0145 0.0111
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0112 0.0145 0.0111
Onchocerca volvulus 0.0137 0.0235 0.1397
Echinococcus granulosus mitogen activated protein kinase 3 0.0084 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0152 0.0287 0.0276
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0981 0.325 0.325
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0151 0.0285 0.0252
Loa Loa (eye worm) TK/FER protein kinase 0.039 0.1138 0.1129
Brugia malayi Thioredoxin reductase 0.2869 1 1
Trichomonas vaginalis mercuric reductase, putative 0.0994 0.3298 1
Echinococcus multilocularis Immunoglobulin 0.0492 0.1504 0.1504
Schistosoma mansoni serine/threonine protein kinase 0.0197 0.0447 0.0447
Schistosoma mansoni protein kinase 0.01 0.0101 0.0101
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0108 0.0128 0.0124
Echinococcus multilocularis tyrosine kinase 0.0098 0.0094 0.0094
Brugia malayi Stress-activated protein kinase jnk-1 0.0258 0.0665 0.0655
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0165 0.0394
Schistosoma mansoni hypothetical protein 0.0152 0.0287 0.0287
Plasmodium vivax serine/threonine protein kinase, putative 0.0084 0.0042 0.0007
Schistosoma mansoni cell adhesion molecule 0.0293 0.0791 0.0791
Brugia malayi hypothetical protein 0.0108 0.0128 0.0116
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0264 0.0687 0.0655
Loa Loa (eye worm) hypothetical protein 0.0089 0.0061 0.0051
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.091 0.2997 0.299
Onchocerca volvulus Tyrosine kinase homolog 0.0473 0.1433 0.8646
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0089 0.0061 0.0061
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0086 0.0052 0.0052
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0127 0.0199 0.0189
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0133 0.0219 0.0219
Brugia malayi EGF-like domain containing protein 0.029 0.078 0.0769
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Echinococcus multilocularis protein kinase shaggy 0.0127 0.0199 0.0199
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0092 0.0074 0.0074
Giardia lamblia Kinase, CMGC CK2 0.01 0.0101 0.018
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0212 0.0499 0.0499
Plasmodium falciparum NIMA related kinase 1 0.0135 0.0225 0.0191
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Brugia malayi Protein kinase domain containing protein 0.0113 0.0149 0.0137
Trichomonas vaginalis AGC family protein kinase 0.0293 0.079 0.2311
Schistosoma mansoni titin 0.0126 0.0194 0.0194
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0101 0.0103 0.0093
Schistosoma mansoni hypothetical protein 0.0141 0.0248 0.0248
Echinococcus multilocularis cyclin dependent kinase 5 0.0118 0.0165 0.0165
Onchocerca volvulus 0.0186 0.0409 0.2453
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0264 0.0687 0.2955
Schistosoma mansoni titin 0.0177 0.0375 0.0375
Giardia lamblia Kinase, NEK 0.0135 0.0225 0.0561
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0264 0.0687 0.1994
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0064 0.0064
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0293 0.0791 0.0791
Schistosoma mansoni serine/threonine protein kinase 0.0182 0.0396 0.0395
Brugia malayi Immunoglobulin I-set domain containing protein 0.0278 0.0738 0.0727
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0375 0.0363
Loa Loa (eye worm) hypothetical protein 0.0134 0.0221 0.021
Loa Loa (eye worm) CAMK protein kinase 0.0177 0.0375 0.0364
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0125 0.019 0.0156
Giardia lamblia Kinase, CMGC CDK 0.0118 0.0165 0.0377
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0085 0.0048 0.0044
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0257 0.0675
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0264 0.0687 0.0655
Schistosoma mansoni serine/threonine kinase 0.0165 0.0334 0.0334
Loa Loa (eye worm) TK protein kinase 0.0183 0.0397 0.0387
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0094 0.0084
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0994 0.3298 1
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0044 0.0024
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0152 0.0287 0.0287
Echinococcus granulosus calcium activated potassium channel 0.0133 0.022 0.022
Schistosoma mansoni protein kinase 0.0108 0.013 0.013
Brugia malayi Protein kinase domain containing protein 0.0084 0.0042 0.0031
Leishmania major hypothetical protein, conserved 0.0264 0.0687 0.0655
Loa Loa (eye worm) hypothetical protein 0.0249 0.0633 0.0623
Brugia malayi Immunoglobulin I-set domain containing protein 0.018 0.0386 0.0375
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0083 0.0039 0.0028
Trichomonas vaginalis STE family protein kinase 0.0135 0.0225 0.0577
Schistosoma mansoni serine/threonine protein kinase 0.0463 0.1397 0.1397
Echinococcus multilocularis tyrosine protein kinase 0.0277 0.0733 0.0733
Schistosoma mansoni glutamate synthase 0.0264 0.0687 0.0687
Trichomonas vaginalis CAMK family protein kinase 0.0125 0.0191 0.0474
Trypanosoma cruzi trypanothione reductase, putative 0.0994 0.3298 0.3295
Brugia malayi Immunoglobulin I-set domain containing protein 0.0278 0.0738 0.0727
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Echinococcus granulosus mitogen activated protein kinase 0.0084 0.0044 0.0044
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0119 0.0169 0.0169
Trichomonas vaginalis AGC family protein kinase 0.0293 0.079 0.2311
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0994 0.3298 0.3274
Giardia lamblia Kinase, AGC PKA 0.0154 0.0295 0.0777
Entamoeba histolytica protein kinase, putative 0.0074 0.0008 0.0036
Trichomonas vaginalis AGC family protein kinase 0.0293 0.079 0.2311
Loa Loa (eye worm) hypothetical protein 0.0264 0.0687 0.0677
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0118 0.0165 0.0131
Brugia malayi SRC-1 0.022 0.0528 0.0517
Onchocerca volvulus Peroxidasin homolog 0.0126 0.0194 0.1152
Echinococcus granulosus serine:threonine protein kinase 0.0113 0.0149 0.0149
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0264 0.0687 0.1994
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0103 0.0103
Schistosoma mansoni hypothetical protein 0.0152 0.0287 0.0287
Echinococcus granulosus tyrosine protein kinase Fyn 0.022 0.0528 0.0528
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0194 0.0183
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0237 0.059 0.059
Brugia malayi kettin 0.0126 0.0194 0.0183
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.0257 0.1105
Trypanosoma cruzi cdc2-related kinase 3 0.0118 0.0165 0.0161
Echinococcus multilocularis neurogenic locus protein delta 0.029 0.078 0.078
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0084 0.0044 0.001
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Echinococcus multilocularis tyrosine protein kinase Fyn 0.022 0.0528 0.0528
Loa Loa (eye worm) hypothetical protein 0.0174 0.0365 0.0355
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0137 0.0234 0.0201
Echinococcus multilocularis serine:threonine protein kinase N2 0.0165 0.0334 0.0334
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0182 0.0396 0.0385
Onchocerca volvulus 0.0281 0.0748 0.4505
Schistosoma mansoni growth factor receptor-bound protein 0.0091 0.0068 0.0068
Schistosoma mansoni notch 0.029 0.078 0.078
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0086 0.0052 0.0052
Onchocerca volvulus 0.0535 0.1657 1
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0199 0.0453 0.0453
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0343 0.0969 0.0969
Trichomonas vaginalis AGC family protein kinase 0.0185 0.0404 0.1128
Plasmodium falciparum ferrodoxin reductase-like protein 0.0264 0.0687 0.0655
Echinococcus granulosus roundabout 2 0.0293 0.0791 0.0791
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0121 0.0177 0.0143
Onchocerca volvulus 0.029 0.078 0.4693
Echinococcus granulosus serine:threonine protein kinase N2 0.0125 0.0189 0.0189
Brugia malayi hypothetical protein 0.0535 0.1657 0.1647
Onchocerca volvulus Slit protein homolog 0.0317 0.0878 0.5289
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.029 0.078 0.078
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0278 0.0738 0.0728
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Loa Loa (eye worm) hypothetical protein 0.0317 0.0878 0.0868
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0108 0.0128 0.0124
Leishmania major protein kinase A catalytic subunit 0.0112 0.0145 0.0111
Loa Loa (eye worm) animal heme peroxidase 0.0126 0.0194 0.0184
Echinococcus granulosus serine:threonine kinase SAD 1 0.009 0.0064 0.0064
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0082 0.0035 0.0001
Brugia malayi putative serine/threonine kinase SADA gamma 0.009 0.0064 0.0052
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0152 0.0287 0.0287
Brugia malayi Protein kinase domain containing protein 0.0098 0.0094 0.0083
Echinococcus multilocularis titin 0.0126 0.0194 0.0194
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0246 0.0623 0.0623
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0994 0.3298 0.3275
Brugia malayi Protein kinase domain containing protein 0.019 0.0423 0.0412
Loa Loa (eye worm) cyclin domain-containing protein 0.0712 0.2287 0.2279
Brugia malayi hypothetical protein 0.0098 0.0094 0.0083
Onchocerca volvulus 0.0535 0.1657 1
Echinococcus granulosus serine threonine protein kinase nrc 0.0154 0.0295 0.0295
Echinococcus granulosus delta-like protein 1 0.029 0.078 0.078
Echinococcus granulosus protein kinase c iota type 0.0285 0.0763 0.0763
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0167 0.034 0.034
Brugia malayi C1-like domain containing protein 0.0213 0.0505 0.0494
Onchocerca volvulus 0.0126 0.0194 0.1152
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0103 0.0204
Trichomonas vaginalis CK1 family protein kinase 0.0108 0.013 0.0287
Echinococcus granulosus protein jagged 2 0.029 0.078 0.078
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Loa Loa (eye worm) TK/ALK protein kinase 0.0274 0.0721 0.0712
Entamoeba histolytica protein kinase, putative 0.0144 0.0257 0.1105
Onchocerca volvulus 0.0535 0.1657 1
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0072 0.0000052153 0.0000052153
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0264 0.0687 0.0683
Echinococcus granulosus c src tyrosine kinase 0.0135 0.0226 0.0226
Plasmodium vivax thioredoxin reductase, putative 0.2869 1 1
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0149 0.0344
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0264 0.0687 0.0687
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Echinococcus multilocularis tyrosine protein kinase Src42A 0.022 0.0528 0.0528
Trypanosoma cruzi casein kinase, putative 0.0108 0.013 0.0126
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0264 0.0687 0.0655
Toxoplasma gondii AGC kinase 0.0284 0.076 0.0728
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0101 0.0197
Onchocerca volvulus 0.0535 0.1657 1
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0114 0.0152 0.0152
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0383 0.1113 0.1113
Schistosoma mansoni hemicentin 0.0141 0.0248 0.0248
Brugia malayi hypothetical protein 0.0535 0.1657 0.1647
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0479 0.1457 0.1457
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0264 0.0687 0.1853
Schistosoma mansoni hypothetical protein 0.0264 0.0687 0.0687
Loa Loa (eye worm) hypothetical protein 0.0535 0.1657 0.1648
Brugia malayi Immunoglobulin I-set domain containing protein 0.0293 0.0791 0.0781
Echinococcus multilocularis growth factor receptor bound protein 2 0.0089 0.0061 0.0061
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0264 0.0687 0.0677
Brugia malayi Cadherin domain containing protein 0.029 0.078 0.0769
Brugia malayi pregnancy-associated plasma protein-A 0.0535 0.1657 0.1647
Giardia lamblia Kinase, CMGC DYRK 0.0137 0.0234 0.059
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0182 0.0396 0.0396
Trypanosoma brucei SNF1-related protein kinases, putative 0.009 0.0064 0.003
Schistosoma mansoni protein kinase 0.0086 0.0052 0.0052
Schistosoma mansoni notch 0.029 0.078 0.078
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Brugia malayi Immunoglobulin I-set domain containing protein 0.0363 0.1041 0.103
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0994 0.3298 0.3298
Trichomonas vaginalis AGC family protein kinase 0.0135 0.0225 0.0577
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.0165 0.0165
Echinococcus granulosus Glutaredoxin protein 5 0.0119 0.0169 0.0169
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0126 0.0194 0.0184
Brugia malayi Immunoglobulin I-set domain containing protein 0.0141 0.0248 0.0237
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0165 0.0334 0.0334
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0103 0.0103
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0118 0.0165 0.0131
Schistosoma mansoni sulfide quinone reductase 0.0264 0.0687 0.0687
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0141 0.0248 0.0238
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0227 0.0555 0.0545
Loa Loa (eye worm) hypothetical protein 0.0231 0.0568 0.0558
Echinococcus multilocularis cyclin dependent kinase 1 0.0118 0.0165 0.0165
Loa Loa (eye worm) one IG domain family member 0.0126 0.0194 0.0184
Loa Loa (eye worm) hypothetical protein 0.0152 0.0287 0.0276
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0177 0.0177
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0264 0.0687 0.0687
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0126 0.0194 0.0194
Echinococcus granulosus glutamate synthase 0.0264 0.0687 0.0687
Leishmania major protein kinase, putative 0.0144 0.0257 0.0223
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0619 0.0619
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0094 0.0084
Treponema pallidum NADH oxidase 0.0994 0.3298 1
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0157 0.0304 0.03
Plasmodium falciparum calcium-dependent protein kinase 4 0.0101 0.0103 0.0069
Leishmania major NADH dehydrogenase, putative 0.0264 0.0687 0.0655
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0151 0.0285 0.0281
Onchocerca volvulus 0.0126 0.0194 0.1152
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0126 0.0195 0.0195
Echinococcus granulosus casein kinase I delta 0.0108 0.013 0.013
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0084 0.0044 0.001
Echinococcus multilocularis protein kinase c iota type 0.0285 0.0763 0.0763
Echinococcus granulosus Immunoglobulin 0.0152 0.0287 0.0287
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Echinococcus granulosus protein kinase shaggy 0.0127 0.0199 0.0199
Entamoeba histolytica protein kinase, putative 0.0086 0.0052 0.0225
Echinococcus granulosus twitchin 0.0654 0.2081 0.2081
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.009 0.0064 0.003
Trichomonas vaginalis STE family protein kinase 0.0086 0.0052 0.0048
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.022 0.022
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0101 0.0103 0.0068
Onchocerca volvulus 0.029 0.078 0.4693
Echinococcus multilocularis neuroglian 0.0293 0.0791 0.0791
Echinococcus granulosus roundabout 2 0.0293 0.0791 0.0791
Echinococcus granulosus Immunoglobulin 0.0492 0.1504 0.1504
Schistosoma mansoni cell adhesion molecule 0.0659 0.2101 0.2101
Echinococcus granulosus slit 2 protein 0.0317 0.0878 0.0878
Echinococcus granulosus microtubule associated protein 2 0.0761 0.2463 0.2463
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Plasmodium falciparum serine/threonine protein kinase, putative 0.0144 0.0257 0.0223
Echinococcus multilocularis roundabout 2 0.0293 0.0791 0.0791
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0264 0.0687 0.2955
Brugia malayi intracellular kinase 0.0127 0.0199 0.0188
Plasmodium vivax apical sushi protein, putative 0.0535 0.1657 0.1628
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.01 0.0101 0.009
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0165 0.0394
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0994 0.3298 0.3275
Schistosoma mansoni neuroglian 0.0293 0.0791 0.0791
Schistosoma mansoni notch 0.029 0.078 0.078
Brugia malayi Immunoglobulin I-set domain containing protein 0.0991 0.3286 0.3278
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.022 0.0528 0.0528
Entamoeba histolytica protein kinase, putative 0.0121 0.0177 0.0761
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Brugia malayi Serine/threonine-protein kinase SULU 0.0217 0.0521 0.051
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0121 0.0177 0.0167
Plasmodium falciparum glutathione reductase 0.2869 1 1
Brugia malayi Protein kinase domain containing protein 0.0165 0.0334 0.0323
Echinococcus multilocularis serine:threonine protein kinase 0.0113 0.0149 0.0149
Schistosoma mansoni protein kinase 0.0151 0.0283 0.0283
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0085 0.0048 0.0204
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0137 0.0234 0.0231
Entamoeba histolytica PH domain containing protein kinase, putative 0.0163 0.0326 0.1402
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0264 0.0687 0.1994
Echinococcus multilocularis tyrosine protein kinase Fgr 0.022 0.0528 0.0528
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0044 0.0024
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0085 0.0048 0.0044
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0143 0.0254 0.0254
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0264 0.0687 0.0676
Brugia malayi serine/threonine-protein kinase PAK 7 0.0227 0.0555 0.0544
Echinococcus granulosus tyrosine protein kinase otk 0.0278 0.0738 0.0738
Echinococcus multilocularis protein tyrosine kinase 0.0533 0.1649 0.1649
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0086 0.0052 0.0052
Onchocerca volvulus Neurogenic locus notch homolog 0.029 0.078 0.4693
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0207 0.0482 0.0472
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0127 0.0199 0.0195
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0084 0.0042 0.0032
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0162 0.0321 0.0311
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0223 0.0541 0.0541
Echinococcus granulosus defective proboscis extension response 0.0492 0.1504 0.1504
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0994 0.3298 0.2803
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0101 0.0103 0.0069
Schistosoma mansoni protein kinase 0.0231 0.0569 0.0569
Brugia malayi protein kinase C3,putative 0.0155 0.0299 0.0288
Plasmodium falciparum apical sushi protein 0.0535 0.1657 0.1628
Entamoeba histolytica protein kinase, putative 0.0165 0.0334 0.1437
Onchocerca volvulus 0.0108 0.013 0.0765
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0194 0.0183
Brugia malayi Protein kinase c protein 2 0.0115 0.0154 0.0143
Plasmodium falciparum thioredoxin reductase 0.2869 1 1
Echinococcus multilocularis serine:threonine protein kinase 3 0.0251 0.064 0.064
Leishmania major protein kinase A catalytic subunit isoform 2 0.0112 0.0145 0.0111
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0293 0.0791 0.0782
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Toxoplasma gondii rhoptry neck protein RON1 0.0535 0.1657 0.1628
Echinococcus granulosus titin 0.0177 0.0375 0.0375
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0264 0.0687 0.1853
Echinococcus granulosus epidermal growth factor receptor 0.059 0.1852 0.1852
Echinococcus multilocularis netrin receptor unc 5 0.018 0.0386 0.0386
Schistosoma mansoni g1/s-specific cyclin C 0.1427 0.4846 0.4846
Brugia malayi Animal haem peroxidase family protein 0.0126 0.0194 0.0183
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.009 0.0064 0.0054
Schistosoma mansoni septate junction protein 0.029 0.078 0.078
Schistosoma mansoni nck2/grb4 0.0089 0.0061 0.0061
Trypanosoma cruzi trypanothione reductase, putative 0.2869 1 1
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0086 0.0052 0.0052
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0108 0.0128 0.0128
Brugia malayi Protein kinase domain containing protein 0.0185 0.0404 0.0393
Plasmodium vivax unspecified product 0.01 0.0101 0.0066
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Echinococcus multilocularis tyrosine protein kinase Fyn 0.022 0.0528 0.0528
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0116 0.0159 0.0148
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Echinococcus multilocularis calcium activated potassium channel 0.0133 0.022 0.022
Schistosoma mansoni nephrin 0.0293 0.0791 0.0791
Schistosoma mansoni sulfide quinone reductase 0.0264 0.0687 0.0687
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0161 0.032 0.031
Echinococcus granulosus Vam6:Vps39 protein 0.0108 0.0128 0.0128
Brugia malayi Fibronectin type III domain containing protein 0.0507 0.1558 0.1548
Loa Loa (eye worm) hypothetical protein 0.0223 0.0541 0.0531
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0278 0.0738 0.0738
Brugia malayi Casein kinase II, alpha chain 0.01 0.0101 0.0089
Loa Loa (eye worm) programmed cell death 8 0.0264 0.0687 0.0677
Echinococcus granulosus nervana 2 0.0119 0.0169 0.0169
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0082 0.0037 0.0037
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0101 0.0197
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0139 0.0239 0.0239
Schistosoma mansoni serine/threonine protein kinase 0.0317 0.0875 0.0875
Giardia lamblia Kinase, CMGC GSK 0.0127 0.0199 0.0482
Schistosoma mansoni hypothetical protein 0.029 0.078 0.078
Echinococcus multilocularis cyclin dependent kinase 9 0.0079 0.0026 0.0026
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0137 0.0234 0.0224
Loa Loa (eye worm) hypothetical protein 0.0278 0.0738 0.0728
Brugia malayi Prion-like- 0.0126 0.0194 0.0183
Echinococcus multilocularis mitogen activated protein kinase 0.0084 0.0044 0.0044
Echinococcus multilocularis 0.0116 0.0158 0.0158
Schistosoma mansoni hypothetical protein 0.0152 0.0287 0.0287
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0126 0.0194 0.0184
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0264 0.0687 0.0687
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0264 0.0687 0.0655
Echinococcus multilocularis thioredoxin glutathione reductase 0.2869 1 1
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0492 0.1504 0.1504
Echinococcus multilocularis down syndrome cell adhesion 0.0126 0.0194 0.0194
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0357 0.1018 0.1009
Loa Loa (eye worm) CDC7 protein kinase 0.009 0.0065 0.0055
Plasmodium vivax casein kinase 1, putative 0.0108 0.013 0.0095
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0077 0.0019 0.0019
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0108 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0086 0.005 0.004
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0264 0.0686 0.0686
Echinococcus multilocularis cyclin dependent kinase 9 0.0087 0.0054 0.0054
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0145 0.0333
Echinococcus multilocularis mitogen activated protein kinase 14 0.0157 0.0304 0.0304
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0135 0.0226 0.0226
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0194 0.0183
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0264 0.0687 0.0655
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.022 0.0528 0.0528
Brugia malayi basement membrane proteoglycan 0.0152 0.0287 0.0275
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0151 0.0285 0.0275
Loa Loa (eye worm) hypothetical protein 0.009 0.0064 0.0053
Echinococcus granulosus activin receptor type 0.0081 0.0034 0.0034
Echinococcus granulosus netrin receptor unc 5 0.018 0.0386 0.0386
Onchocerca volvulus 0.0535 0.1657 1
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0065 0.0087
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0152 0.0287 0.0287
Mycobacterium ulcerans monoxygenase 0.0264 0.0687 0.1853
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0182 0.0396 0.0384
Brugia malayi Protein kinase domain containing protein 0.0098 0.0094 0.0083
Echinococcus multilocularis Immunoglobulin 0.0152 0.0287 0.0287
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0118 0.0165 0.0155
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0994 0.3298 0.3275
Schistosoma mansoni vam6/vps39 related 0.0108 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0771 0.2498 0.249
Echinococcus multilocularis mitogen activated protein kinase 11 0.0157 0.0304 0.0304
Schistosoma mansoni tyrosine kinase 0.0389 0.1136 0.1135
Echinococcus granulosus epidermal growth factor receptor 0.0389 0.1136 0.1136
Brugia malayi Protein kinase domain containing protein 0.0082 0.0037 0.0025
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0383 0.1113 0.1103
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0098 0.0094 0.0406
Entamoeba histolytica protein kinase, putative 0.0084 0.0042 0.0181
Echinococcus multilocularis mitogen activated protein kinase 11 0.0157 0.0304 0.0304
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0112 0.0145 0.0111
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0994 0.3298 0.3298
Trichomonas vaginalis AGC family protein kinase 0.0293 0.079 0.2311
Schistosoma mansoni tyrosine kinase 0.022 0.0528 0.0528
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0154 0.0295 0.0295
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0264 0.0687 0.0687
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0264 0.0687 0.1994
Entamoeba histolytica casein kinase, putative 0.01 0.0101 0.0433
Trypanosoma brucei aurora B kinase 0.0144 0.0257 0.0223
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0126 0.0194 0.0194
Echinococcus multilocularis c src tyrosine kinase 0.0135 0.0226 0.0226
Loa Loa (eye worm) AUR protein kinase 0.0144 0.0257 0.0247
Brugia malayi Calcium binding EGF domain containing protein 0.029 0.078 0.0769
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0284 0.076 0.075
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0686 0.1992
Echinococcus granulosus casein kinase I delta 0.0108 0.013 0.013
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0084 0.0044 0.0041
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0264 0.0687 0.0655
Echinococcus multilocularis tyrosine protein kinase Abl 0.0135 0.0226 0.0226
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0334 0.0334
Echinococcus multilocularis C type lectin domian containing protein 0.0535 0.1657 0.1657
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0137 0.0234 0.0201
Brugia malayi Variant SH3 domain containing protein 0.0089 0.0061 0.005
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0151 0.0285 0.0252
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0144 0.0257 0.0257
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0112 0.0145 0.0145
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.022 0.0528 0.0528
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Brugia malayi Protein kinase domain containing protein 0.0098 0.0094 0.0083
Trypanosoma cruzi casein kinase, putative 0.0108 0.013 0.0126
Echinococcus multilocularis tyrosine protein kinase shark 0.0304 0.0829 0.0829
Entamoeba histolytica disulphide oxidoreductase, putative 0.0264 0.0687 0.2955
Schistosoma mansoni cell adhesion molecule 0.0152 0.0287 0.0287
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0126 0.0195 0.0195
Schistosoma mansoni hypothetical protein 0.0152 0.0287 0.0287
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.022 0.022
Brugia malayi Protein kinase domain containing protein 0.0581 0.1821 0.1811
Brugia malayi hypothetical protein 0.0535 0.1657 0.1647
Schistosoma mansoni hypothetical protein 0.0126 0.0194 0.0194
Brugia malayi Protein kinase domain containing protein 0.0189 0.042 0.0409
Onchocerca volvulus 0.0098 0.0094 0.0549
Brugia malayi Protein kinase domain containing protein 0.0942 0.3111 0.3103
Giardia lamblia Kinase, CAMK CAMKL 0.0097 0.0091 0.0151
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0194 0.0183
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0264 0.0687 0.0687
Brugia malayi EGF-like domain containing protein 0.0317 0.0878 0.0867
Schistosoma mansoni titin 0.0126 0.0194 0.0194
Mycobacterium ulcerans NADH dehydrogenase 0.0264 0.0687 0.1853
Loa Loa (eye worm) disorganized muscle protein 1 0.0126 0.0194 0.0184
Echinococcus multilocularis neurogenic locus notch protein 0.029 0.078 0.078
Echinococcus granulosus thioredoxin glutathione reductase 0.2869 1 1
Loa Loa (eye worm) hypothetical protein 0.0595 0.1872 0.1863
Brugia malayi Protein kinase domain containing protein 0.0121 0.0177 0.0165
Loa Loa (eye worm) TK/ABL protein kinase 0.0098 0.0094 0.0084
Echinococcus granulosus basement membrane specific heparan sulfate 0.0152 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0152 0.0287 0.0276
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0194 0.0183
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0098 0.0094 0.0094
Entamoeba histolytica protein kinase , putative 0.0144 0.0257 0.1105
Schistosoma mansoni protein kinase 0.0421 0.1249 0.1249
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0126 0.0194 0.0184
Brugia malayi Variant SH3 domain containing protein 0.0089 0.0061 0.005
Schistosoma mansoni tyrosine kinase 0.0237 0.059 0.059
Leishmania major protein kinase, putative 0.0101 0.0103 0.0069
Brugia malayi Calcium binding EGF domain containing protein 0.029 0.078 0.0769
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0321 0.0889 0.088
Brugia malayi SH2 domain containing protein 0.0098 0.0094 0.0083
Brugia malayi serine/threonine protein kinase 6 0.0144 0.0257 0.0246
Brugia malayi protein-tyrosine kinase 0.0183 0.0397 0.0386
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0217 0.0521 0.0521
Loa Loa (eye worm) hypothetical protein 0.0493 0.1505 0.1496
Brugia malayi glutamate synthase 0.0264 0.0687 0.0676
Brugia malayi Cadherin domain containing protein 0.029 0.078 0.0769
Onchocerca volvulus Serine\/threonine kinase homolog 0.0162 0.0321 0.1918
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0994 0.3298 0.3295
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0101 0.0197
Loa Loa (eye worm) hypothetical protein 0.0278 0.0739 0.0729
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0121 0.0177 0.0173
Echinococcus multilocularis lachesin 0.0278 0.0738 0.0738
Entamoeba histolytica protein kinase, putative 0.0293 0.079 0.34
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0264 0.0687 0.2955
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0492 0.1504 0.1504
Echinococcus granulosus protein kinase C gamma type 0.0205 0.0475 0.0475
Schistosoma mansoni tyrosine kinase 0.0389 0.1136 0.1135
Echinococcus granulosus Immunoglobulin subtype 0.0152 0.0287 0.0287
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0199 0.0453 0.0453
Toxoplasma gondii AGC kinase 0.0112 0.0145 0.0111
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0994 0.3298 1
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.023 0.0565 0.0565
Schistosoma mansoni netrin receptor unc5 0.0152 0.0287 0.0287
Echinococcus granulosus neural cadherin 0.029 0.078 0.078
Trichomonas vaginalis glutathione reductase, putative 0.0994 0.3298 1
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0144 0.0257 0.0223
Echinococcus granulosus cGMP dependent protein kinase 1 0.0133 0.0219 0.0219
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0101 0.0197
Schistosoma mansoni septate junction protein 0.0152 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0492 0.1504 0.1495
Trichomonas vaginalis glutamate synthase, putative 0.0264 0.0687 0.1994
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.022 0.022
Entamoeba histolytica cyclin C, putative 0.0722 0.2324 1
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0084 0.0042 0.0039
Loa Loa (eye worm) hypothetical protein 0.0108 0.0128 0.0117
Echinococcus multilocularis 0.0151 0.0283 0.0283
Echinococcus multilocularis casein kinase I alpha 0.0108 0.013 0.013
Brugia malayi Sex muscle abnormal protein 5 0.0089 0.0061 0.005
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0126 0.0194 0.0194
Brugia malayi Immunoglobulin I-set domain containing protein 0.0141 0.0248 0.0237
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Loa Loa (eye worm) hypothetical protein 0.0138 0.0237 0.0227
Schistosoma mansoni septate junction protein 0.0152 0.0287 0.0287
Echinococcus granulosus CDC7 cell division cycle 7 0.009 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.0535 0.1657 0.1648
Schistosoma mansoni growth factor receptor-bound protein 0.0089 0.0061 0.0061
Echinococcus multilocularis glutamate synthase 0.0264 0.0687 0.0687
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0044 0.0044
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.0257 0.0257
Loa Loa (eye worm) Notch2 0.029 0.078 0.077
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0264 0.0687 0.1994
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0264 0.0687 0.0687
Trypanosoma brucei NADH dehydrogenase 0.0264 0.0687 0.0655
Brugia malayi Fes/CIP4 homology domain containing protein 0.011 0.0136 0.0124
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0112 0.0145 0.0145
Echinococcus granulosus C type lectin domian containing protein 0.0535 0.1657 0.1657
Echinococcus multilocularis hemicentin 1 0.0278 0.0738 0.0738
Giardia lamblia Kinase, AGC PKA 0.0112 0.0145 0.0316
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0165 0.0334 0.0334
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0245 0.0619 0.0619
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0994 0.3298 0.3275
Echinococcus granulosus casein kinase i 0.0108 0.013 0.013
Trypanosoma brucei rac serine-threonine kinase, putative 0.0293 0.079 0.0759
Loa Loa (eye worm) notch protein 0.029 0.078 0.077
Loa Loa (eye worm) hypothetical protein 0.0098 0.0094 0.0084
Echinococcus multilocularis fibropellin Ia 0.029 0.078 0.078
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.0634 0.0634
Onchocerca volvulus 0.0098 0.0094 0.0549
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0264 0.0687 0.0655
Trichomonas vaginalis STE family protein kinase 0.0086 0.0052 0.0048
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0092 0.0074 0.0063
Loa Loa (eye worm) LAD-2 short isoform 0.0152 0.0287 0.0276
Trypanosoma cruzi aurora B kinase, putative 0.0144 0.0257 0.0253
Echinococcus granulosus cyclin dependent kinase 0.0118 0.0165 0.0165
Entamoeba histolytica protein kinase domain containing protein 0.01 0.0101 0.0433
Trichomonas vaginalis CAMK family protein kinase 0.0125 0.0191 0.0474
Echinococcus multilocularis titin 0.0126 0.0194 0.0194
Brugia malayi serine/threonine kinase 12 0.0144 0.0257 0.0246
Onchocerca volvulus 0.0535 0.1657 1
Mycobacterium ulcerans ferredoxin reductase 0.0264 0.0687 0.1853
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.073 0.2354 0.2345
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0112 0.0145 0.0142
Brugia malayi Immunoglobulin I-set domain containing protein 0.0152 0.0287 0.0275
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0217 0.0521 0.0521
Echinococcus multilocularis Immunoglobulin 0.0492 0.1504 0.1504
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0994 0.3298 0.3275
Loa Loa (eye worm) TK protein kinase 0.0131 0.021 0.02
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0492 0.1504 0.1504
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0112 0.0145 0.0142
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0112 0.0145 0.0145
Onchocerca volvulus 0.0535 0.1657 1
Loa Loa (eye worm) TK/ROR protein kinase 0.0172 0.0359 0.0349
Loa Loa (eye worm) AGC/AKT protein kinase 0.0293 0.079 0.0781
Brugia malayi Immunoglobulin I-set domain containing protein 0.0152 0.0288 0.0276
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0152 0.0287 0.0287
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0194 0.0183
Loa Loa (eye worm) hypothetical protein 0.0535 0.1657 0.1648
Schistosoma mansoni serine/threonine protein kinase 0.0383 0.1113 0.1112
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Loa Loa (eye worm) hypothetical protein 0.0278 0.0738 0.0728
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0141 0.0248 0.0238
Loa Loa (eye worm) TK protein kinase 0.0338 0.0952 0.0942
Echinococcus granulosus dual specificity protein kinase clk2 0.0151 0.0285 0.0285
Onchocerca volvulus 0.0134 0.0221 0.1313
Brugia malayi Immunoglobulin I-set domain containing protein 0.0278 0.0738 0.0727
Loa Loa (eye worm) TK protein kinase 0.0277 0.0733 0.0723
Giardia lamblia Aurora kinase 0.0144 0.0257 0.0659
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0141 0.0248 0.0248
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0084 0.0044 0.001
Schistosoma mansoni hypothetical protein 0.0098 0.0094 0.0094
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0101 0.0103 0.0103
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0118 0.0165 0.0155
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0101 0.0103 0.0069
Brugia malayi EGF-like domain containing protein 0.029 0.078 0.0769
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.2869 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0127 0.0199 0.0498
Brugia malayi Furin-like cysteine rich region family protein 0.059 0.1852 0.1842
Echinococcus multilocularis tyrosine protein kinase Src64B 0.022 0.0528 0.0528
Echinococcus granulosus tyrosine protein kinase ABL1 0.0098 0.0094 0.0094
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0082 0.0037 0.0026
Mycobacterium ulcerans hypothetical protein 0.0264 0.0687 0.1853
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0293 0.0791 0.0791
Trypanosoma brucei hypothetical protein, conserved 0.0264 0.0687 0.0655
Schistosoma mansoni serine/threonine-protein kinase 0.0163 0.0326 0.0326
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.0623 0.0623
Loa Loa (eye worm) AUR protein kinase 0.0144 0.0257 0.0247
Echinococcus multilocularis tyrosine protein kinase otk 0.0278 0.0738 0.0738
Schistosoma mansoni hypothetical protein 0.0108 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0086 0.005 0.004
Schistosoma mansoni serine/threonine protein kinase 0.0212 0.0499 0.0499
Echinococcus multilocularis peroxidasin 0.0278 0.0739 0.0739
Onchocerca volvulus 0.009 0.0065 0.0372
Loa Loa (eye worm) hypothetical protein 0.0113 0.0149 0.0139
Brugia malayi Immunoglobulin domain containing protein 0.0152 0.0287 0.0275
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.0219 0.0219
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0197 0.0447 0.0437
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0082 0.0035 0.0001
Entamoeba histolytica serine/threonine protein kinase, putative 0.009 0.0064 0.0275
Echinococcus granulosus tyrosine protein kinase HCK 0.0131 0.021 0.021
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0994 0.3298 1
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0234 0.0607
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0084 0.0044 0.0034
Trichomonas vaginalis AGC family protein kinase 0.0293 0.079 0.2311
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0086 0.0052 0.0052
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0994 0.3298 0.3295
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0112 0.0145 0.0145
Schistosoma mansoni tyrosine kinase 0.0433 0.1292 0.1292
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Loa Loa (eye worm) glutathione reductase 0.2869 1 1
Schistosoma mansoni notch 0.029 0.078 0.078
Entamoeba histolytica protein kinase domain containing protein 0.0127 0.0199 0.0856
Onchocerca volvulus Netrin receptor homolog 0.0154 0.0294 0.1754
Brugia malayi notch-like transmembrane receptor 0.029 0.078 0.0769
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0101 0.0103 0.0069
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0357 0.1018 0.1018
Plasmodium falciparum serine/threonine protein kinase 0.0084 0.0042 0.0008
Echinococcus granulosus fibroblast growth factor receptor 4 0.0237 0.059 0.059
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0085 0.0048 0.0204
Schistosoma mansoni cell adhesion molecule 0.0152 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0644 0.2047 0.2039
Echinococcus granulosus hypothetical protein 0.0116 0.0158 0.0158
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0084 0.0044 0.0041
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0448 0.1346 0.1346
Echinococcus granulosus casein kinase I alpha 0.0108 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Schistosoma mansoni protein kinase 0.0144 0.0257 0.0257
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0264 0.0687 0.1994
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0264 0.0687 0.1853
Echinococcus granulosus protein jagged 1 0.029 0.078 0.078
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0994 0.3298 0.3295
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0108 0.013 0.012
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0264 0.0687 0.1994
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0086 0.0052 0.0052
Brugia malayi Cyclin, N-terminal domain containing protein 0.0712 0.2287 0.2278
Echinococcus granulosus neurogenic locus notch protein 0.029 0.078 0.078
Giardia lamblia Kinase, STE STE20 0.0086 0.0052 0.0031
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0154 0.0295 0.0292
Echinococcus granulosus cyclin dependent kinase 19 0.0942 0.3111 0.3111
Schistosoma mansoni septate junction protein 0.0278 0.0738 0.0738
Brugia malayi Protein kinase domain containing protein 0.0212 0.0503 0.0492
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0084 0.0044 0.0041
Giardia lamblia Thioredoxin reductase 0.0264 0.0687 0.198
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0084 0.0044 0.0041
Giardia lamblia Kinase, CMGC CDK 0.0118 0.0165 0.0377
Echinococcus granulosus neurogenic locus notch protein 4 0.029 0.078 0.078
Brugia malayi EGF-like domain containing protein 0.029 0.078 0.0769
Entamoeba histolytica protein kinase, putative 0.0131 0.021 0.0905
Echinococcus granulosus protein kinase c epsilon type 0.0207 0.0482 0.0482
Entamoeba histolytica PH domain containing protein kinase, putative 0.0121 0.0176 0.0757
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.009 0.0064 0.003
Brugia malayi Protein kinase domain containing protein 0.0274 0.0722 0.0711
Echinococcus granulosus c4b binding protein beta chain 0.0535 0.1657 0.1657
Loa Loa (eye worm) hypothetical protein 0.0825 0.2693 0.2686
Entamoeba histolytica protein kinase, putative 0.0082 0.0037 0.0157
Schistosoma mansoni cell adhesion molecule 0.0141 0.0248 0.0248
Schistosoma mansoni rap gtpase-activating protein 0.0108 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0092 0.0074 0.0074
Trypanosoma brucei cdc2-related kinase 3 0.0118 0.0165 0.0131
Echinococcus multilocularis transfer RNA-Phe 0.0141 0.0248 0.0248
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0994 0.3298 0.2803
Schistosoma mansoni hypothetical protein 0.0152 0.0287 0.0287
Brugia malayi protein kinase C II. 0.0207 0.0482 0.0471
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0079 0.0026 0.0016
Echinococcus multilocularis protein jagged 1 0.029 0.078 0.078
Echinococcus multilocularis protein kinase c epsilon type 0.0207 0.0482 0.0482
Schistosoma mansoni hypothetical protein 0.0126 0.0194 0.0194
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0167 0.034 0.033
Trypanosoma brucei cdc2-related kinase 1 0.0118 0.0165 0.0131
Giardia lamblia Glutamate synthase 0.0264 0.0687 0.198
Entamoeba histolytica protein kinase, putative 0.0084 0.0042 0.0181
Schistosoma mansoni hypothetical protein 0.029 0.078 0.078
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0197 0.0447 0.0447
Loa Loa (eye worm) hypothetical protein 0.0141 0.0248 0.0238
Trichomonas vaginalis CMGC family protein kinase 0.0127 0.0199 0.0498
Brugia malayi casein kinase 1, delta 0.0108 0.013 0.0119
Brugia malayi p70 ribosomal S6 kinase beta 0.0284 0.076 0.0749
Mycobacterium ulcerans dehydrogenase 0.0264 0.0687 0.1853
Brugia malayi map kinase activated protein kinase protein 2 0.0383 0.1113 0.1102
Plasmodium falciparum glutathione reductase 0.0994 0.3298 0.3275
Plasmodium falciparum serine/threonine protein kinase KIN 0.009 0.0064 0.003
Echinococcus granulosus serine/threonine protein kinase 0.0163 0.0326 0.0326
Schistosoma mansoni serine/threonine protein kinase 0.0258 0.0665 0.0665
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.023 0.0565 0.0565
Toxoplasma gondii CMGC kinase, CK2 family 0.01 0.0101 0.0067
Echinococcus multilocularis neural cadherin 0.029 0.078 0.078
Onchocerca volvulus 0.0126 0.0195 0.1159
Echinococcus multilocularis serine:threonine protein kinase 0.0113 0.0149 0.0149
Echinococcus multilocularis dual specificity 0.0137 0.0234 0.0234
Echinococcus multilocularis cyclin dependent kinase 19 0.0942 0.3111 0.3111
Entamoeba histolytica thioredoxin reductase, putative 0.0264 0.0687 0.2955
Loa Loa (eye worm) TK/EGFR protein kinase 0.059 0.1852 0.1843
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0182 0.0396 0.0396
Echinococcus granulosus tyrosine protein kinase Fps85D 0.039 0.1138 0.1138
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0217 0.0521 0.0511
Onchocerca volvulus 0.0141 0.0248 0.1478
Onchocerca volvulus 0.0108 0.0128 0.075
Schistosoma mansoni slit 0.0126 0.0195 0.0195
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0994 0.3298 1
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.0375 0.0375
Echinococcus granulosus cyclin dependent kinase 9 0.0087 0.0054 0.0054
Brugia malayi serine/threonine-protein kinase plk-2 0.0264 0.0686 0.0675
Schistosoma mansoni notch 0.029 0.078 0.078
Brugia malayi hypothetical protein 0.0507 0.1558 0.1548
Giardia lamblia Kinase, NEK 0.0135 0.0225 0.0561
Entamoeba histolytica cell division protein kinase 2, putative 0.0126 0.0192 0.0828
Trypanosoma cruzi hypothetical protein, conserved 0.0264 0.0687 0.0683
Schistosoma mansoni serine/threonine protein kinase 0.0209 0.049 0.049
Giardia lamblia Kinase, AGC AKT 0.0116 0.0159 0.0359
Echinococcus granulosus serine:threonine protein kinase N2 0.029 0.078 0.078
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0112 0.0145 0.0145
Echinococcus granulosus neuropeptide receptor 0.079 0.2567 0.2567
Brugia malayi Protein kinase domain containing protein 0.0184 0.0402 0.0391
Loa Loa (eye worm) hypothetical protein 0.0278 0.0738 0.0728
Loa Loa (eye worm) hypothetical protein 0.0098 0.0094 0.0083
Loa Loa (eye worm) hypothetical protein 0.0444 0.1331 0.1322
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0264 0.0687 0.1853
Trichomonas vaginalis AGC family protein kinase 0.0194 0.0435 0.1222
Loa Loa (eye worm) projectin 0.0141 0.0248 0.0238
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0112 0.0145 0.0111
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0421 0.1249 0.1249
Brugia malayi cell division control protein 2 homolog 0.0118 0.0165 0.0154
Brugia malayi Muscle positioning protein 4 0.029 0.078 0.0769
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0094 0.0084
Schistosoma mansoni cell polarity protein 0.029 0.078 0.078
Schistosoma mansoni serine/threonine protein kinase 0.0264 0.0686 0.0686
Echinococcus granulosus ephrin type A receptor 4 A 0.0108 0.0128 0.0128
Entamoeba histolytica protein kinase, putative 0.0293 0.079 0.34
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0144 0.0257 0.1105
Echinococcus multilocularis aurora kinase A 0.0144 0.0257 0.0257
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0246 0.0623 0.0614
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.022 0.0528 0.0528
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0152 0.0287 0.0287
Schistosoma mansoni serine/threonine protein kinase 0.0137 0.0234 0.0234
Entamoeba histolytica cell division protein kinase 2, putative 0.0118 0.0165 0.071
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0157 0.0304 0.03
Echinococcus multilocularis serine:threonine protein kinase 38 0.0165 0.0334 0.0334
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0264 0.0687 0.2955
Echinococcus multilocularis Immunoglobulin subtype 0.0152 0.0287 0.0287
Echinococcus multilocularis protein jagged 1 0.029 0.078 0.078
Brugia malayi Kinase associated domain 1 family protein 0.0098 0.0094 0.0082
Brugia malayi Immunoglobulin domain containing protein 0.0152 0.0287 0.0275
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0081 0.0034 0.0031
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.073 0.2354 0.2345
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0264 0.0686 0.0686
Echinococcus granulosus mitogen activated protein kinase 11 0.0157 0.0304 0.0304
Onchocerca volvulus 0.029 0.078 0.4693
Echinococcus granulosus c-Jun N-terminal kinases 0.0258 0.0665 0.0665
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0108 0.013 0.0126
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0994 0.3298 0.3295
Echinococcus multilocularis death associated protein kinase 1 0.082 0.2675 0.2675
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.0219 0.0219
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.009 0.0064 0.006
Entamoeba histolytica protein kinase domain containing protein 0.0079 0.0026 0.0112
Schistosoma mansoni tyrosine kinase 0.0251 0.0642 0.0642
Echinococcus granulosus cGMP dependent protein kinase 0.0133 0.0219 0.0219
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0264 0.0687 0.0687
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0686 0.1992
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0072 0.0000052153 0.0000052153
Schistosoma mansoni hypothetical protein 0.029 0.078 0.078
Brugia malayi Hr1 repeat family protein 0.029 0.078 0.0769
Schistosoma mansoni protein kinase 0.0421 0.1249 0.1249
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0094 0.0084
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0264 0.0687 0.198
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0212 0.0499 0.0499
Trypanosoma cruzi NADH dehydrogenase, putative 0.0264 0.0687 0.0683
Trichomonas vaginalis CK1 family protein kinase 0.0108 0.013 0.0287
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0194 0.0183
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0092 0.0074 0.0074
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0101 0.0103 0.0068
Schistosoma mansoni ephrin receptor 0.0108 0.0128 0.0128
Schistosoma mansoni basigin related 0.0152 0.0287 0.0287
Plasmodium vivax calcium-dependent protein kinase, putative 0.0101 0.0103 0.0068
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0712 0.2287 0.2287
Brugia malayi Protein kinase domain containing protein 0.009 0.0065 0.0054
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0264 0.0687 0.0655
Echinococcus multilocularis casein kinase I gamma 0.0209 0.049 0.049
Schistosoma mansoni protein kinase C mu 0.0213 0.0505 0.0505
Echinococcus multilocularis tyrosine protein kinase Blk 0.0183 0.0397 0.0397
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0084 0.0042 0.0008
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Plasmodium falciparum glycogen synthase kinase 3 0.0127 0.0199 0.0165
Schistosoma mansoni serine/threonine protein kinase 0.023 0.0565 0.0565
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0126 0.0194 0.0194
Trichomonas vaginalis CK1 family protein kinase 0.0108 0.013 0.0287
Echinococcus multilocularis epidermal growth factor receptor 0.059 0.1852 0.1852
Brugia malayi Immunoglobulin domain containing protein 0.0152 0.0287 0.0275
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0264 0.0687 0.0654
Schistosoma mansoni nephrin related 0.0152 0.0287 0.0287
Entamoeba histolytica serine/threonine protein kinase, putative 0.0264 0.0686 0.2952
Schistosoma mansoni protein kinase 0.0231 0.0569 0.0569
Schistosoma mansoni cell adhesion molecule 0.0141 0.0248 0.0248
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0199 0.0453 0.0443
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0942 0.3111 0.3103
Schistosoma mansoni serine/threonine protein kinase 0.0343 0.0969 0.0969
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0114 0.0152 0.0152
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0084 0.0042 0.0008
Echinococcus granulosus cyclin dependent kinase 1 0.0118 0.0165 0.0165
Giardia lamblia Kinase, STE STE20 0.0085 0.0048 0.0016
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0163 0.0326 0.0322
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Schistosoma mansoni hypothetical protein 0.0126 0.0194 0.0194
Brugia malayi hypothetical protein 0.0217 0.0521 0.051
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0064 0.0064
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0152 0.0287 0.0287
Schistosoma mansoni serine/threonine protein kinase 0.023 0.0565 0.0565
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0336 0.0945 0.0935
Brugia malayi hypothetical protein 0.0152 0.0287 0.0275
Onchocerca volvulus 0.0126 0.0194 0.1152
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0343 0.0969 0.5841
Brugia malayi Protein kinase domain containing protein 0.0293 0.079 0.078
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0103 0.0103
Schistosoma mansoni notch 0.029 0.078 0.078
Echinococcus multilocularis serine:threonine kinase SAD 1 0.009 0.0064 0.0064
Onchocerca volvulus Putative titin 0.0126 0.0194 0.1152
Brugia malayi Variant SH3 domain containing protein 0.0092 0.0074 0.0062
Entamoeba histolytica protein kinase domain containing protein 0.0137 0.0234 0.1009
Schistosoma mansoni basigin related 0.0152 0.0287 0.0287
Trypanosoma brucei protein kinase, putative 0.0092 0.0072 0.0038
Schistosoma mansoni cell adhesion molecule 0.0278 0.0738 0.0738
Schistosoma mansoni c4b-binding protein beta chain 0.0535 0.1657 0.1657
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0127 0.0199 0.0199
Onchocerca volvulus Neurogenic locus notch protein homolog 0.029 0.078 0.4693
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0173 0.0361 0.0351
Trichomonas vaginalis CAMK family protein kinase 0.0271 0.0714 0.2076
Brugia malayi serine/threonine-protein kinase 6 0.0144 0.0257 0.0246
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0479 0.1457 0.1457
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0154 0.0293 0.0283
Echinococcus multilocularis insulin receptor 0.0433 0.1292 0.1292
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0258 0.0665 0.0665
Echinococcus multilocularis rho associated protein kinase 0.0317 0.0875 0.0875
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0143 0.0255 0.0255
Echinococcus granulosus titin 0.0126 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0145 0.0145
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0101 0.0103 0.0093
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0094 0.0084
Brugia malayi Immunoglobulin I-set domain containing protein 0.0141 0.0248 0.0237
Brugia malayi GCC2 and GCC3 family protein 0.0825 0.2693 0.2685
Echinococcus multilocularis dual specificity protein kinase clk2 0.0151 0.0285 0.0285
Loa Loa (eye worm) hypothetical protein 0.0507 0.1558 0.1549
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0343 0.0969 0.0959
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0108 0.013 0.012
Loa Loa (eye worm) hypothetical protein 0.0116 0.0158 0.0148
Brugia malayi Protein kinase domain containing protein 0.0539 0.167 0.166
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0257 0.0675
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Giardia lamblia Kinase, CDC7 0.009 0.0065 0.007
Schistosoma mansoni hypothetical protein 0.0126 0.0194 0.0194
Trypanosoma cruzi polo-like protein kinase, putative 0.0264 0.0686 0.0683
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0264 0.0687 0.0655
Schistosoma mansoni septate junction protein 0.0278 0.0738 0.0738
Echinococcus multilocularis expressed protein 0.0084 0.0042 0.0042
Brugia malayi Protein kinase domain containing protein 0.0118 0.0165 0.0154
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0343 0.0969 0.096
Schistosoma mansoni serine/threonine protein kinase 0.0086 0.0052 0.0052
Echinococcus granulosus serine:threonine protein kinase 0.0113 0.0149 0.0149
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0231 0.0569 0.0569
Schistosoma mansoni cell adhesion molecule 0.0126 0.0194 0.0194
Schistosoma mansoni hypothetical protein 0.0126 0.0194 0.0194
Echinococcus multilocularis serine:threonine protein kinase N2 0.029 0.078 0.078
Onchocerca volvulus Serine\/threonine kinase homolog 0.0264 0.0686 0.4128
Onchocerca volvulus 0.0098 0.0094 0.0549
Trypanosoma cruzi cdc2-related kinase 1 0.0118 0.0165 0.0161
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0264 0.0686 0.0676
Brugia malayi Protein kinase domain 0.0086 0.0052 0.0041
Schistosoma mansoni titin 0.0278 0.0738 0.0738
Echinococcus multilocularis mitogen activated protein kinase 14 0.0157 0.0304 0.0304
Echinococcus granulosus roundabout 2 0.0786 0.2552 0.2552
Brugia malayi Protein kinase domain containing protein 0.0581 0.1821 0.1811
Echinococcus granulosus contactin 0.0293 0.0791 0.0791
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0154 0.0295 0.0261
Echinococcus granulosus neuroglian 0.0293 0.0791 0.0791
Loa Loa (eye worm) hypothetical protein 0.0535 0.1657 0.1648
Schistosoma mansoni atypical protein kinase C 0.0291 0.0784 0.0784
Onchocerca volvulus 0.0098 0.0094 0.0549
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0264 0.0687 0.0687
Schistosoma mansoni serine/threonine protein kinase 0.0207 0.0482 0.0482
Echinococcus granulosus raf serine:threonine protein kinase 0.0086 0.0052 0.0052
Echinococcus granulosus serine:threonine protein kinase 3 0.0251 0.064 0.064
Giardia lamblia Kinase, CMGC GSK 0.0127 0.0199 0.0482
Brugia malayi hypothetical protein 0.0535 0.1657 0.1647
Loa Loa (eye worm) hypothetical protein 0.0278 0.0738 0.0728
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0581 0.1821 0.1812
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0101 0.0197
Plasmodium vivax protein kinase Crk2 0.0118 0.0165 0.013
Trypanosoma brucei trypanothione reductase 0.2869 1 1
Trichomonas vaginalis AGC family protein kinase 0.0293 0.079 0.2311
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0119 0.0169 0.0169
Brugia malayi EGF-like domain containing protein 0.029 0.078 0.0769
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0994 0.3298 0.2803
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0994 0.3298 0.3295
Echinococcus granulosus cyclin 0.0712 0.2287 0.2287
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0108 0.0128 0.0128
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.039 0.1138 0.1138
Giardia lamblia Kinase, CMGC CLK 0.0151 0.0285 0.0745
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0264 0.0687 0.1853
Schistosoma mansoni netrin receptor unc5 0.018 0.0386 0.0386
Brugia malayi Immunoglobulin I-set domain containing protein 0.0293 0.0791 0.0781
Entamoeba histolytica protein kinase domain containing protein 0.0127 0.0199 0.0856
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0037 0.0037
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0251 0.064 0.063
Brugia malayi Immunoglobulin I-set domain containing protein 0.0141 0.0248 0.0237
Loa Loa (eye worm) AGC/PKA protein kinase 0.0112 0.0145 0.0135
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0264 0.0687 0.0654
Schistosoma mansoni hypothetical protein 0.029 0.078 0.078
Onchocerca volvulus 0.0141 0.0248 0.1478
Trichomonas vaginalis AGC family protein kinase 0.0293 0.079 0.2311
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0343 0.0969 0.0969
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.009 0.0064 0.0053
Echinococcus multilocularis epidermal growth factor receptor 0.0389 0.1136 0.1136
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0101 0.0103 0.0103
Trichomonas vaginalis AGC family protein kinase 0.009 0.0064 0.0084
Echinococcus granulosus N chimaerin 0.0092 0.0074 0.0074
Schistosoma mansoni disulfide oxidoreductase 0.0264 0.0687 0.0687
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0194 0.0183
Plasmodium falciparum calcium-dependent protein kinase 1 0.0101 0.0103 0.0069
Echinococcus multilocularis twitchin 0.0161 0.0321 0.0321
Onchocerca volvulus 0.0126 0.0194 0.1152
Trichomonas vaginalis STE family protein kinase 0.0086 0.0052 0.0048
Echinococcus multilocularis N chimaerin 0.0092 0.0074 0.0074
Echinococcus multilocularis casein kinase I alpha 0.0108 0.013 0.013
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0212 0.0499 0.0499
Onchocerca volvulus 0.0127 0.0199 0.1181
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0064 0.0064
Brugia malayi MAP kinase sur-1 0.0084 0.0044 0.0033
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.029 0.078 0.0769
Echinococcus multilocularis microtubule associated protein 2 0.0761 0.2463 0.2463
Brugia malayi hypothetical protein 0.0535 0.1657 0.1647
Onchocerca volvulus Peroxidasin homolog 0.0126 0.0195 0.1159
Onchocerca volvulus 0.0264 0.0687 0.4131
Loa Loa (eye worm) hypothetical protein 0.0101 0.0103 0.0093
Echinococcus multilocularis ephrin type A receptor 4 A 0.0108 0.0128 0.0128
Leishmania major protein kinase A catalytic subunit isoform 1 0.0112 0.0145 0.0111
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0321 0.0321
Brugia malayi Immunoglobulin I-set domain containing protein 0.0278 0.0738 0.0727
Entamoeba histolytica protein kinase, putative 0.0144 0.0257 0.1105
Plasmodium vivax glutathione reductase, putative 0.2869 1 1
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0994 0.3298 1
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0152 0.0287 0.0287
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0064 0.0064
Brugia malayi Protein kinase domain containing protein 0.0098 0.0094 0.0083
Schistosoma mansoni serine/threonine protein kinase 0.0217 0.0521 0.0521
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0264 0.0687 0.1994
Trypanosoma cruzi SNF1-related protein kinases, putative 0.009 0.0064 0.006
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0435 0.1299 0.129
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0994 0.3298 0.329
Echinococcus granulosus tyrosine protein kinase Src42A 0.0139 0.0239 0.0239
Brugia malayi Protein kinase domain containing protein 0.0357 0.1018 0.1008
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0329 0.0918 0.0908
Echinococcus multilocularis c4b binding protein beta chain 0.0535 0.1657 0.1657
Schistosoma mansoni tyrosine kinase 0.0357 0.1019 0.1019
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0264 0.0687 0.2955
Trichomonas vaginalis apoptosis inducing factor, putative 0.0264 0.0687 0.1994
Echinococcus multilocularis tyrosine protein kinase Srms 0.0183 0.0397 0.0397
Echinococcus granulosus hemicentin 1 0.0278 0.0738 0.0738
Echinococcus granulosus tyrosine protein kinase Srms 0.0491 0.1497 0.1497
Plasmodium vivax ferrodoxin reductase, putative 0.0264 0.0687 0.0654
Echinococcus multilocularis cyclin dependent kinase 1 0.0118 0.0165 0.0165
Schistosoma mansoni serine/threonine kinase 0.022 0.053 0.053
Echinococcus granulosus tyrosine kinase 0.0098 0.0094 0.0094
Entamoeba histolytica p21-activated kinase 0.0095 0.0083 0.0357
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.0165 0.0165
Brugia malayi Immunoglobulin I-set domain containing protein 0.0141 0.0248 0.0237
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0234 0.0607
Loa Loa (eye worm) transcription factor SMAD2 0.0132 0.0214 0.0203
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0044 0.0024
Echinococcus multilocularis dual specificity 0.0137 0.0234 0.0234
Toxoplasma gondii NADPH-glutathione reductase 0.0994 0.3298 0.3275
Echinococcus granulosus tyrosine protein kinase shark 0.0304 0.0829 0.0829
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0127 0.0199 0.0165
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0383 0.1113 0.1113
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0264 0.0687 0.0655
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0162 0.0321 0.0321
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0112 0.0145 0.0111
Echinococcus granulosus titin 0.0177 0.0375 0.0375
Echinococcus multilocularis nervana 2 0.0119 0.0169 0.0169
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0135 0.0225 0.0191
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.009 0.0064 0.003
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0172 0.0359 0.0359
Schistosoma mansoni titin 0.0141 0.0248 0.0248
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0686 0.1992
Echinococcus multilocularis Immunoglobulin 0.0152 0.0287 0.0287
Plasmodium vivax serine/threonine kinase-1, putative 0.0151 0.0285 0.0251
Entamoeba histolytica hypothetical protein 0.0366 0.1051 0.4521
Trichomonas vaginalis STE family protein kinase 0.0085 0.0048 0.0034
Echinococcus granulosus tyrosine protein kinase Blk 0.0183 0.0397 0.0397
Brugia malayi Protein kinase domain containing protein 0.0209 0.049 0.0479
Loa Loa (eye worm) hypothetical protein 0.0134 0.0221 0.021
Echinococcus multilocularis neurogenic locus notch protein 0.029 0.078 0.078
Loa Loa (eye worm) AGC/PKN protein kinase 0.029 0.078 0.077
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0101 0.0103 0.0103
Giardia lamblia High cysteine protein 0.029 0.078 0.2265
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0103 0.0103
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0101 0.0103 0.0092
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0094 0.0084
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0231 0.0569 0.0569
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0264 0.0687 0.0683
Leishmania major protein kinase, putative 0.0085 0.0048 0.0013
Schistosoma mansoni protein kinase 0.0189 0.042 0.042
Echinococcus granulosus tyrosine protein kinase 0.0277 0.0733 0.0733
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0143 0.0254 0.0254
Loa Loa (eye worm) hypothetical protein 0.0278 0.0738 0.0728
Schistosoma mansoni hypothetical protein 0.0126 0.0194 0.0194
Plasmodium falciparum thioredoxin reductase 0.0994 0.3298 0.3275
Loa Loa (eye worm) hypothetical protein 0.0535 0.1657 0.1648
Echinococcus multilocularis hemicentin 1 0.0278 0.0738 0.0738
Schistosoma mansoni roundabout 0.0278 0.0738 0.0738
Trypanosoma cruzi casein kinase, putative 0.0108 0.013 0.0126
Toxoplasma gondii thioredoxin reductase 0.2869 1 1
Echinococcus multilocularis tyrosine protein kinase HCK 0.0131 0.021 0.021
Echinococcus multilocularis hypothetical protein 0.0098 0.0094 0.0094
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0118 0.0165 0.0155
Echinococcus granulosus leucine rich repeat containing protein 4 0.0126 0.0194 0.0194
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0321 0.0321
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0994 0.3298 0.3295
Echinococcus multilocularis titin 0.0177 0.0375 0.0375
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Schistosoma mansoni titin 0.0126 0.0194 0.0194
Toxoplasma gondii rhoptry neck protein RON9 0.0535 0.1657 0.1628
Echinococcus multilocularis NCK adaptor protein 0.0091 0.0068 0.0068
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0994 0.3298 1
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0065 0.0087
Leishmania major hypothetical protein, conserved 0.0264 0.0687 0.0655
Schistosoma mansoni neuropeptide receptor 0.079 0.2567 0.2567
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0152 0.0287 0.0287
Echinococcus multilocularis casein kinase i 0.0108 0.013 0.013
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0094 0.0084
Brugia malayi Egg laying defective protein 4 0.0133 0.0219 0.0208
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0278 0.0738 0.0738
Loa Loa (eye worm) AGC/PKA protein kinase 0.0112 0.0145 0.0135
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0994 0.3298 0.3274
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0994 0.3298 0.3275
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0141 0.0248 0.0238
Echinococcus multilocularis casein kinase I alpha 0.0108 0.013 0.013
Brugia malayi Cam kinase protein 1 0.0101 0.0103 0.0092
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0127 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0152 0.0287 0.0276
Brugia malayi Immunoglobulin I-set domain containing protein 0.0141 0.0248 0.0237
Echinococcus multilocularis tyrosine protein kinase Fyn 0.022 0.0528 0.0528
Schistosoma mansoni tyrosine kinase 0.0343 0.0971 0.0971
Loa Loa (eye worm) hypothetical protein 0.0112 0.0145 0.0135
Loa Loa (eye worm) hypothetical protein 0.0186 0.0409 0.0399
Echinococcus granulosus casein kinase I alpha 0.0108 0.013 0.013
Loa Loa (eye worm) TK/FAK protein kinase 0.0539 0.167 0.1661
Loa Loa (eye worm) hypothetical protein 0.0152 0.0287 0.0276
Onchocerca volvulus 0.009 0.0065 0.0372
Entamoeba histolytica protein kinase, putative 0.0102 0.0108 0.0463
Brugia malayi protein unc-22 0.0177 0.0375 0.0363
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0162 0.0321 0.0321
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0112 0.0145 0.0145
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0994 0.3298 0.3295
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0044 0.0024
Echinococcus granulosus cGMP dependent protein kinase 1 0.0133 0.0219 0.0219
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0126 0.0194 0.0194
Loa Loa (eye worm) thioredoxin reductase 0.2869 1 1
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0212 0.0499 0.0499
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.022 0.0528 0.0528
Loa Loa (eye worm) hypothetical protein 0.0108 0.0128 0.0117
Echinococcus granulosus Protein kinase C brain isozyme 0.0245 0.0619 0.0619
Echinococcus granulosus protein tyrosine kinase 0.0533 0.1649 0.1649
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0113 0.0149 0.0139
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0392 0.1143 0.1143
Echinococcus granulosus casein kinase I gamma 0.0209 0.049 0.049
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0065 0.0065
Echinococcus granulosus tyrosine protein kinase Src42A 0.022 0.0528 0.0528
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0644 0.2047 0.2047
Echinococcus granulosus lachesin 0.0278 0.0738 0.0738
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0112 0.0145 0.0145
Onchocerca volvulus 0.0535 0.1657 1
Schistosoma mansoni protein kinase 0.0081 0.0034 0.0034
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0094 0.0084
Schistosoma mansoni basigin related 0.0152 0.0287 0.0287
Brugia malayi Calcium binding EGF domain containing protein 0.029 0.078 0.0769
Echinococcus granulosus cyclin dependent kinase 9 0.0079 0.0026 0.0026
Schistosoma mansoni tyrosine kinase 0.0135 0.0226 0.0226
Entamoeba histolytica protein kinase, putative 0.0127 0.0199 0.0856

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1.5 uM Inhibitory concentration against hepatitis C virus helicase ChEMBL. 15633995

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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