Detailed information for compound 1745230

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 519.612 | Formula: C19H28K2N3O7P
  • H donors: 5 H acceptors: 6 LogP: 1.07 Rotable bonds: 15
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCOP(=O)(N[C@H](C(=O)N[C@H](C(=O)NCC(=O)[O-])Cc1ccccc1)[C@H](CC)C)[O-].[K+].[K+]
  • InChi: 1S/C19H30N3O7P.2K/c1-4-13(3)17(22-30(27,28)29-5-2)19(26)21-15(18(25)20-12-16(23)24)11-14-9-7-6-8-10-14;;/h6-10,13,15,17H,4-5,11-12H2,1-3H3,(H,20,25)(H,21,26)(H,23,24)(H2,22,27,28);;/q;2*+1/p-2/t13-,15-,17-;;/m0../s1
  • InChiKey: IMPWMVXHMXYDQF-HVNWSVKNSA-L  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0162 0.0507
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Schistosoma mansoni adenoreceptor 0.0006 0.0005 0.0005
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0281 0.043
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.1771 0.1767
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0031
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0007 0.0022 0.0016
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.032 0.032
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0008 0.0025 0.0032
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0025 0.0012
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0295 0.036
Echinococcus multilocularis lamin dm0 0.0056 0.058 0.0576
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0009 0.0045 0.0103
Schistosoma mansoni amine GPCR 0.0006 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0013 0.0088 0.013
Trichomonas vaginalis bromodomain containing protein, putative 0.0008 0.0025 0.0034
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0008 0.0025 0.0025
Schistosoma mansoni biogenic amine (5HT) receptor 0.0006 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0226 0.0269
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0177 0.0173
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.0178 0.027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0153 0.023
Echinococcus granulosus histone acetyltransferase KAT2B 0.0303 0.343 0.3427
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0226 0.0284
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.0178 0.0174
Brugia malayi Cytochrome P450 family protein 0.0024 0.0208 0.0316
Echinococcus multilocularis musashi 0.0056 0.058 0.0576
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0178 0.027
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0295 0.019
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0008 0.0025 0.0004
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.1 0.3637
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0057 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Schistosoma mansoni ferritin 0.0008 0.0032 0.0032
Leishmania major hypothetical protein, conserved,predicted bromodomain protein 0.0008 0.0025 0.0012
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0178 0.0178
Brugia malayi polybromodomain protein 0.0008 0.0025 0.0031
Loa Loa (eye worm) hypothetical protein 0.0563 0.6439 1
Trichomonas vaginalis DNA-directed RNA polymerase I subunit, putative 0.0013 0.0085 0.0242
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0058 0.061 0.0606
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0008 0.0025 0.0032
Loa Loa (eye worm) hypothetical protein 0.0021 0.0178 0.027
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Brugia malayi ecdysteroid receptor 0.0008 0.0025 0.0032
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.024 0.2712 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Toxoplasma gondii bromodomain-containing protein 0.0008 0.0025 0.0033
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0178 0.0174
Schistosoma mansoni phd finger protein 0.0008 0.0025 0.0025
Trypanosoma brucei calpain, putative 0.024 0.2712 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0281 0.043
Toxoplasma gondii exonuclease III APE 0.002 0.0162 0.1449
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.1 0.3381
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.1262 0.4281
Loa Loa (eye worm) hypothetical protein 0.0026 0.0235 0.0359
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0226 0.1646
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0007 0.0022 0.0016
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.0178 0.0174
Schistosoma mansoni apoferritin-2 0.0008 0.0032 0.0032
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0178 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Brugia malayi Bromodomain containing protein 0.0008 0.0025 0.0031
Schistosoma mansoni neuropeptide receptor 0.0006 0.0005 0.0005
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.024 0.2712 1
Schistosoma mansoni lamin 0.0056 0.058 0.058
Loa Loa (eye worm) hypothetical protein 0.0055 0.0568 0.0876
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0178 0.0178
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0008 0.0025 0.002
Trypanosoma brucei polo-like protein kinase 0.0092 0.1 0.3637
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.0665 0.7613 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0177 0.0268
Giardia lamblia Hypothetical protein 0.0009 0.0045 0.0206
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0182 0.0182
Echinococcus granulosus ecdysone induced protein 78C 0.0008 0.0025 0.002
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0036 0.0032
Trypanosoma brucei RNA polymerase I second largest subunit 0.0009 0.0043 0.0081
Echinococcus granulosus polybromo 1 0.0008 0.0025 0.002
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0344 0.1129
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.0178 0.0174
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0088 0.0252
Echinococcus granulosus intermediate filament protein 0.0056 0.058 0.0576
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0006 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0008 0.0025 0.0025
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Loa Loa (eye worm) hypothetical protein 0.0019 0.0153 0.023
Echinococcus granulosus transcription initiation factor TFIID subunit 1 0.0008 0.0025 0.002
Schistosoma mansoni neuropeptide receptor 0.0006 0.0005 0.0005
Brugia malayi hypothetical protein 0.0021 0.0177 0.0268
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.1 0.3381
Schistosoma mansoni lamin 0.0056 0.058 0.058
Plasmodium falciparum bromodomain protein, putative 0.0008 0.0025 0.0004
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0008 0.0025 0.0025
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0226 0.073
Leishmania major glycosyl hydrolase-like protein 0.0013 0.0088 0.0248
Schistosoma mansoni amine GPCR 0.0006 0.0005 0.0005
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0162 0.0158
Loa Loa (eye worm) BRM protein 0.0008 0.0025 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0008 0.0025 0.0025
Trypanosoma brucei DNA-directed RNA polymerase III, putative 0.0013 0.0085 0.0237
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0008 0.0025 0.0025
Echinococcus multilocularis peregrin 0.0008 0.0025 0.002
Onchocerca volvulus 0.0007 0.0022 0.0058
Schistosoma mansoni ferritin 0.0008 0.0032 0.0032
Schistosoma mansoni bromodomain containing protein 0.0009 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0009 0.0045 0.0062
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0009 0.0038 0.0078
Brugia malayi Glycosyl hydrolases family 31 protein 0.0159 0.1771 0.2745
Schistosoma mansoni neuropeptide F-like receptor 0.0006 0.0005 0.0005
Trypanosoma brucei DNA-directed RNA polymerase II subunit 2, putative 0.0013 0.0085 0.0237
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0006 0.0005 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0006 0.0005 0.0005
Onchocerca volvulus 0.0259 0.2929 1
Echinococcus granulosus cpg binding protein 0.0032 0.0301 0.0296
Toxoplasma gondii DNA-directed RNA polymerase III RPC2 0.0013 0.0085 0.0655
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Schistosoma mansoni ap endonuclease 0.002 0.0162 0.0162
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0008 0.0025 0.0033
Giardia lamblia Kinase, PLK 0.0092 0.1 1
Onchocerca volvulus 0.0008 0.0025 0.0069
Schistosoma mansoni intermediate filament proteins 0.0056 0.058 0.058
Schistosoma mansoni bromodomain containing protein 0.0009 0.0044 0.0044
Loa Loa (eye worm) steroid hormone receptor 0.0008 0.0025 0.0032
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0295 0.019
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0007 0.0022 0.0016
Echinococcus multilocularis ferritin 0.0008 0.0032 0.0027
Echinococcus granulosus geminin 0.0165 0.1844 0.184
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0162 0.1411
Loa Loa (eye worm) RGS-3 protein 0.0021 0.0178 0.027
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0177 0.0173
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0344 0.2596
Trypanosoma cruzi RNA polymerase I second largest subunit, putative 0.0009 0.0043 0.0081
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0008 0.0025 0.0025
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0006 0.0005 0.0005
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.032 0.0316
Brugia malayi Pre-SET motif family protein 0.0033 0.032 0.0491
Plasmodium falciparum bromodomain protein 2, putative 0.0008 0.0025 0.0004
Trichomonas vaginalis bromodomain-containing protein 4, brd4, putative 0.0008 0.0025 0.0034
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.024 0.2712 1
Echinococcus multilocularis protein kinase C binding protein 1 0.0008 0.0025 0.002
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Schistosoma mansoni DNA helicase recq5 0.0009 0.0039 0.0039
Plasmodium falciparum beta-ketoacyl-ACP synthase III 0.0665 0.7613 1
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.024 0.2712 1
Onchocerca volvulus UPF0528 protein homolog 0.0045 0.0451 0.1526
Schistosoma mansoni cpg binding protein 0.0032 0.0301 0.0301
Trypanosoma cruzi Bromodomain, putative 0.0008 0.0025 0.0012
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0141 0.0172
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0295 0.0961
Echinococcus granulosus RUN 0.0021 0.0177 0.0173
Toxoplasma gondii bromodomain-containing protein 0.0008 0.0025 0.0033
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0022 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0159 0.1771 0.2745
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0178 0.0178
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0015 0.00000000014512
Entamoeba histolytica ankyrin repeat protein, putative 0.0008 0.0025 0.0025
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0063 0.066 0.2372
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Brugia malayi Bromodomain containing protein 0.0008 0.0025 0.0031
Trypanosoma cruzi Bromodomain, putative 0.0008 0.0025 0.0012
Plasmodium vivax hypothetical protein, conserved 0.0008 0.0025 0.0004
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Leishmania major hypothetical protein, conserved 0.0008 0.0025 0.0012
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0178 0.0178
Brugia malayi Bromodomain containing protein 0.0008 0.0025 0.0031
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0178 0.0174
Mycobacterium ulcerans arylsulfatase, AslA 0.0009 0.0045 0.0031
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0162 0.0468
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.1771 0.1767
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0008 0.0025 0.0032
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Echinococcus multilocularis PH interacting protein 0.0008 0.0025 0.002
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0177 0.0173
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.0182 0.0177
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Schistosoma mansoni rab6-interacting 0.0021 0.0177 0.0177
Onchocerca volvulus 0.0008 0.0025 0.0069
Echinococcus granulosus histone acetyltransferase KAT2B 0.0092 0.0994 0.0989
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0226 0.0759
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.0182 0.0275
Schistosoma mansoni ferritin 0.0008 0.0032 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0162 0.0245
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0153 0.0188
Loa Loa (eye worm) hypothetical protein 0.0025 0.0226 0.0344
Schistosoma mansoni CREB-binding protein 2 0.0008 0.0025 0.0025
Brugia malayi Doublecortin family protein 0.0021 0.0177 0.0268
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0008 0.0025 0.0032
Echinococcus granulosus Bromodomain containing protein 0.0008 0.0025 0.002
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0008 0.0025 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Trypanosoma brucei Bromodomain, putative 0.0008 0.0025 0.0012
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.0611 0.0942
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.0088 0.0248
Mycobacterium tuberculosis DNA-directed RNA polymerase (beta chain) RpoB (transcriptase beta chain) (RNA polymerase beta subunit) 0.0061 0.0641 0.083
Schistosoma mansoni amine GPCR 0.0006 0.0005 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0008 0.0025 0.0032
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0463 0.1538
Schistosoma mansoni hypothetical protein 0.0008 0.0025 0.0025
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0178 0.0561
Toxoplasma gondii bromodomain-containing protein 0.0008 0.0025 0.0033
Schistosoma mansoni thyroid hormone receptor 0.0008 0.0025 0.0025
Toxoplasma gondii bromodomain-containing protein 0.0008 0.0025 0.0033
Onchocerca volvulus 0.0021 0.0177 0.059
Plasmodium vivax SET domain containing protein 0.0009 0.0046 0.0032
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0032
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.024 0.2712 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0235 0.0359
Trichomonas vaginalis bromodomain-containing protein, putative 0.0092 0.0994 0.3359
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0015 0.00000000014512
Echinococcus multilocularis DNA directed RNA polymerase I subunit RPA2 0.0013 0.0085 0.0081
Toxoplasma gondii histone lysine methyltransferase SET1 0.0065 0.0692 0.6893
Entamoeba histolytica bromodomain-containing protein 0.0008 0.0025 0.0025
Echinococcus granulosus Bromodomain containing protein 0.0008 0.0025 0.002
Echinococcus granulosus CREB binding protein 0.0008 0.0025 0.002
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0226 0.0269
Trichomonas vaginalis lymphoid specific helicase, putative 0.0008 0.0025 0.0034
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0009 0.0039 0.0054
Echinococcus multilocularis geminin 0.0165 0.1844 0.184
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0008 0.0025 0.0032
Brugia malayi hypothetical protein 0.0009 0.0045 0.0062
Mycobacterium tuberculosis Possible hydrolase 0.0009 0.0045 0.0046
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0006 0.0005 0.0005
Giardia lamblia Sgs1 DNA helicase, putative 0.0009 0.0039 0.0149
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0141 0.0172
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0311 0.3531 0.3528
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0006 0.0005 0.0005
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0178 0.0178
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0162 0.0186
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0226 0.0269
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0007 0.0022 0.0016
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0008 0.0025 0.0034
Onchocerca volvulus 0.0056 0.058 0.1968
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0031
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0032
Schistosoma mansoni bromodomain-containing protein 3 brd3 0.0008 0.0025 0.0025
Echinococcus multilocularis global transcription activator snf2l2 0.0008 0.0025 0.002
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Echinococcus multilocularis expressed protein 0.0008 0.0032 0.0027
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0344 0.1129
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0022 0.0023
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0105 0.0109
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0344 0.1197
Brugia malayi Steroid receptor seven-up type 2 0.0008 0.0025 0.0032
Schistosoma mansoni biogenic amine receptor 0.0006 0.0005 0.0005
Giardia lamblia DNA-directed RNA polymerase subunit B 0.0009 0.0043 0.0191
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0009 0.0045 0.0137
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0009 0.0039 0.0023
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0344 0.1129
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0008 0.0025 0.0032
Schistosoma mansoni hypothetical protein 0.0006 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0021 0.0178 0.027
Plasmodium vivax bromodomain protein, putative 0.0008 0.0025 0.0004
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0162 0.0186
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Schistosoma mansoni hypothetical protein 0.0165 0.1844 0.1844
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Brugia malayi regulator of G-protein signaling egl-10 0.0021 0.0178 0.027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0008 0.0025 0.0032
Onchocerca volvulus 0.0007 0.0022 0.0058
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0008 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0025 0.0226 0.0344
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Brugia malayi Sulfatase family protein 0.0009 0.0045 0.0062
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0088 0.0252
Echinococcus granulosus DNA directed RNA polymerase III subunit RPC2 0.0013 0.0085 0.0081
Echinococcus granulosus lysosomal alpha glucosidase 0.0159 0.1771 0.1767
Mycobacterium tuberculosis 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) 0.0665 0.7613 1
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0022 0.0016
Brugia malayi nuclear hormone receptor 0.0008 0.0025 0.0032
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0032
Schistosoma mansoni DNA helicase recq1 0.0009 0.0039 0.0039
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0008 0.0025 0.002
Schistosoma mansoni transcription initiation factor tfiid 0.0008 0.0025 0.0025
Mycobacterium tuberculosis Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0009 0.0045 0.0046
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0155 0.0176
Chlamydia trachomatis oxoacyl-ACP synthase III 0.0665 0.7613 1
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Loa Loa (eye worm) hypothetical protein 0.0017 0.0135 0.0202
Treponema pallidum DNA-directed RNA polymerase subunit beta 0.025 0.2818 1
Brugia malayi nuclear receptor NHR-88 0.0008 0.0025 0.0032
Mycobacterium ulcerans arylsulfatase AtsD 0.0009 0.0045 0.0031
Brugia malayi Pre-SET motif family protein 0.0228 0.2567 0.3982
Schistosoma mansoni hypothetical protein 0.0006 0.0005 0.0005
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0178 0.0174
Echinococcus multilocularis thyroid hormone receptor alpha 0.0008 0.0025 0.002
Loa Loa (eye worm) CBP-B 0.0008 0.0025 0.0031
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0015 0.00000000014512
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Schistosoma mansoni alpha glucosidase 0.0035 0.0344 0.0344
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Echinococcus multilocularis FTZ F1 alpha 0.0008 0.0025 0.002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0015 0.00000000014512
Echinococcus granulosus lamin dm0 0.0056 0.058 0.0576
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0226 0.073
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0344 0.0339
Loa Loa (eye worm) hypothetical protein 0.0019 0.0153 0.023
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0032
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0008 0.0025 0.0032
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0057 0.0053
Toxoplasma gondii DNA-directed RNA polymerase I RPA2 0.0009 0.0043 0.0224
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0344 0.1197
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0162 0.0524
Loa Loa (eye worm) hypothetical protein 0.0025 0.0226 0.0344
Echinococcus multilocularis lamin 0.0056 0.058 0.0576
Trypanosoma cruzi calpain cysteine peptidase, putative 0.024 0.2712 1
Trypanosoma brucei calpain-like protein, putative 0.024 0.2712 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0178 0.027
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0039 0.0182
Brugia malayi steroid hormone receptor 0.0008 0.0025 0.0032
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.1 0.3381
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0006 0.0005 0.0005
Giardia lamblia DNA-directed RNA polymerase subunit B 0.0013 0.0085 0.0621
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Trichomonas vaginalis bromodomain containing protein, putative 0.0008 0.0025 0.0034
Trypanosoma brucei glycosyl hydrolase-like protein 0.0013 0.0088 0.0248
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0226 0.0344
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0088 0.0252
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0022 0.0026
Loa Loa (eye worm) hypothetical protein 0.0027 0.0247 0.0377
Schistosoma mansoni acetyl-CoA synthetase 0.0007 0.0022 0.0022
Brugia malayi Glycosyl hydrolases family 31 protein 0.0013 0.0088 0.013
Schistosoma mansoni coup transcription factor 0.0008 0.0025 0.0025
Chlamydia trachomatis DNA-directed RNA polymerase subunit beta 0.025 0.2818 0.3573
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Trypanosoma cruzi Bromodomain, putative 0.0008 0.0025 0.0012
Onchocerca volvulus 0.0033 0.032 0.108
Loa Loa (eye worm) hypothetical protein 0.0021 0.0178 0.027
Echinococcus multilocularis DNA directed RNA polymerase II subunit RPB2 0.0013 0.0085 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0178 0.0178
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0008 0.0032 0.0038
Schistosoma mansoni myosin xvIII 0.0006 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0008 0.0025 0.0025
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0299 0.0294
Onchocerca volvulus 0.003 0.0281 0.0946
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0056 0.058 0.0894
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0008 0.0025 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0178 0.0561
Brugia malayi serine/threonine-protein kinase plk-2 0.0092 0.1 0.1547
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.1 0.3381
Brugia malayi DNA-directed RNA polymerase, beta subunit family protein 0.0013 0.0085 0.0125
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0177 0.0173
Giardia lamblia Hypothetical protein 0.0009 0.0045 0.0206
Schistosoma mansoni biogenic amine receptor 0.0006 0.0005 0.0005
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0008 0.0025 0.002
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Loa Loa (eye worm) intermediate filament protein 0.0056 0.058 0.0894
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0185 0.0181
Loa Loa (eye worm) hypothetical protein 0.0007 0.0022 0.0026
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0015 0.00000000014512
Schistosoma mansoni apoferritin-2 0.0008 0.0032 0.0032
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.1 0.3637
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0226 0.0269
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.024 0.2712 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.024 0.2712 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0063 0.066 0.084
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0177 0.0173
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0178 0.0174
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0177 0.0205
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.1262 0.4612
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0178 0.0561
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0063 0.066 0.1018
Giardia lamblia Histone acetyltransferase GCN5 0.0084 0.0906 0.9031
Toxoplasma gondii histone acetyltransferase TAF1/250 0.0008 0.0025 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0008 0.0025 0.0032
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0178 0.027
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0177 0.0173
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0006 0.0005 0.0005
Mycobacterium ulcerans DNA-directed RNA polymerase subunit beta 0.025 0.2818 0.3684
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0015 0.00000000014512
Plasmodium vivax SET domain protein, putative 0.0033 0.032 0.0394
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0344 0.1129
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0344 0.3314
Leishmania major DNA-directed RNA polymerase polypeptide, putative 0.0013 0.0085 0.0237
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0006 0.0005 0.0005
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0009 0.0045 0.0103
Brugia malayi photoreceptor-specific nuclear receptor 0.0008 0.0025 0.0032
Schistosoma mansoni neuropeptide f receptor 76f 0.0006 0.0005 0.0005
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0063 0.066 0.0655
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.1262 0.4612
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0344 0.1129
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0162 0.0172
Mycobacterium ulcerans hydrolase 0.0009 0.0045 0.0031
Entamoeba histolytica hypothetical protein 0.0021 0.0178 0.1263
Schistosoma mansoni hypothetical protein 0.0006 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0033 0.032 0.0491
Mycobacterium ulcerans arylsulfatase AtsB 0.0009 0.0045 0.0031
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0008 0.0025 0.002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0226 0.0284
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0069 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Trichomonas vaginalis bromodomain containing protein, putative 0.0008 0.0025 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0344 0.0527
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0178 0.0174
Onchocerca volvulus 0.0012 0.007 0.0224
Schistosoma mansoni ferritin 0.0008 0.0032 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0009 0.0036 0.0032
Schistosoma mansoni zinc finger protein 0.0009 0.0044 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0008 0.0025 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0031
Schistosoma mansoni loxhd1 0.0021 0.0177 0.0177
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.1262 0.1955
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0063 0.066 0.0855
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Loa Loa (eye worm) hypothetical protein 0.0009 0.0044 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0008 0.0025 0.0032
Trypanosoma cruzi Bromodomain factor 1 0.0008 0.0025 0.0012
Brugia malayi acetyltransferase, GNAT family protein 0.0311 0.3531 0.548
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.032 0.0316
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0039 0.0054
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0031
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0103 0.0835
Entamoeba histolytica DNA-directed RNA polymerase subunit, putative 0.0013 0.0085 0.0513
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0069 0.0178
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0295 0.2811
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0007 0.0022 0.0016
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.0178 0.0174
Entamoeba histolytica hypothetical protein 0.0008 0.0025 0.0025
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0063 0.066 0.0655
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0092 0.1 0.0996
Trichomonas vaginalis hypothetical protein 0.0008 0.0025 0.0034
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0056 0.0079
Schistosoma mansoni nuclear hormone receptor 0.0008 0.0025 0.0025
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0039 0.0054
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0162 0.0524
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0008 0.0025 0.002
Onchocerca volvulus 0.0025 0.0226 0.0756
Loa Loa (eye worm) bromodomain containing protein 0.0008 0.0025 0.0031
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0008 0.0025 0.002
Echinococcus multilocularis CREB binding protein 0.0008 0.0025 0.002
Loa Loa (eye worm) hypothetical protein 0.0346 0.3934 0.6107
Mycobacterium ulcerans bacterioferritin BfrA 0.0008 0.0032 0.0014
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0036 0.0032
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0013 0.0088 0.0286
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0162 0.0524
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Mycobacterium tuberculosis Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0009 0.0045 0.0046
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.0088 0.0248
Schistosoma mansoni DNA-directed rna polymerase II subunit 0.0013 0.0085 0.0085
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Echinococcus multilocularis dnaJ subfamily B 0.0872 1 1
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0092 0.0994 0.3359
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0295 0.2811
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0022 0.0023
Trichomonas vaginalis bromodomain-containing protein 3, brd3, putative 0.0008 0.0025 0.0034
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.024 0.2712 1
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0153 0.0173
Brugia malayi 6-phosphofructokinase 0.0115 0.1262 0.1955
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Echinococcus multilocularis bromodomain containing protein 8 0.0008 0.0025 0.002
Echinococcus multilocularis expressed protein 0.0408 0.464 0.4638
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0162 0.0524
Trichomonas vaginalis hypothetical protein 0.0008 0.0025 0.0034
Schistosoma mansoni alpha-1 adrenergic receptor 0.0006 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0178 0.0561
Onchocerca volvulus Bromodomain adjacent to zinc finger domain protein 1A homolog 0.0008 0.0025 0.0069
Echinococcus multilocularis 6 phosphofructokinase 0.0115 0.1262 0.1258
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0031
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0088 0.0252
Schistosoma mansoni RAR-like nuclear receptor 0.0008 0.0025 0.0025
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Plasmodium falciparum DNA-directed RNA polymerase I subunit RPA2, putative 0.0009 0.0043 0.0029
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0021 0.0178 0.027
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Echinococcus granulosus zinc finger protein 0.0009 0.0044 0.004
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0008 0.0025 0.0034
Echinococcus multilocularis DNA directed RNA polymerase III subunit RPC2 0.0013 0.0085 0.0081
Brugia malayi BRM protein 0.0008 0.0025 0.0031
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0013 0.0088 0.0537
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0008 0.0025 0.0034
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0247 0.0243
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Schistosoma mansoni polycystin 1-related 0.0021 0.0177 0.0177
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Entamoeba histolytica bromodomain-containing protein 0.0008 0.0025 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0009 0.0039 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0008 0.0025 0.0032
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0311 0.3531 0.3531
Trypanosoma cruzi Bromodomain, putative 0.0008 0.0025 0.0012
Entamoeba histolytica acetyltransferase, GNAT family 0.0084 0.0906 0.7125
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0295 0.036
Schistosoma mansoni ferritin light chain 0.0008 0.0032 0.0032
Entamoeba histolytica bromodomain-containing protein 0.0008 0.0025 0.0025
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.1262 0.4281
Echinococcus granulosus DNA directed RNA polymerase I subunit RPA2 0.0013 0.0085 0.0081
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.0178 0.0174
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0115 0.1262 0.4437
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0162 0.0201
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0006 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0007 0.0022 0.0017
Echinococcus granulosus ferritin 0.0008 0.0032 0.0027
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0153 0.0173
Schistosoma mansoni bromodomain containing protein 0.0008 0.0025 0.0025
Echinococcus granulosus global transcription activator snf2l2 0.0008 0.0025 0.002
Entamoeba histolytica DNA-directed RNA polymerase III subunit 127.6 kDa polypeptide, putative 0.0013 0.0085 0.0513
Mycobacterium ulcerans beta-ketoacyl synthase-like protein 0.0665 0.7613 1
Brugia malayi Bromodomain containing protein 0.0008 0.0025 0.0031
Trypanosoma brucei Bromodomain factor 1 0.0008 0.0025 0.0012
Loa Loa (eye worm) histone methyltransferase 0.001 0.0057 0.0082
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0295 0.2769
Echinococcus multilocularis RUN 0.0021 0.0177 0.0173
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0022 0.0026
Brugia malayi polybromodomain protein 0.0008 0.0025 0.0031
Trichomonas vaginalis bromodomain containing protein, putative 0.0008 0.0025 0.0034
Toxoplasma gondii DNA-directed RNA polymerase II RPB2 0.0013 0.0085 0.0655
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.032 0.032
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0177 0.0205
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0295 0.036
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.1 0.3381
Plasmodium falciparum DNA-directed RNA polymerase subunit beta, putative 0.0068 0.072 0.092
Echinococcus multilocularis 0.0008 0.0025 0.002
Schistosoma mansoni neuropeptide F-like receptor 0.0006 0.0005 0.0005
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0295 0.0961
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0007 0.0022 0.0016
Plasmodium vivax bromodomain protein, putative 0.0008 0.0025 0.0004
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0008 0.0025 0.0032
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0022 0.0026
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0092 0.0994 1
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0115 0.1262 0.4416
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Plasmodium vivax DNA-directed RNA polymerase III subunit, putative 0.0013 0.0085 0.0084
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0178 0.0561
Echinococcus granulosus 6 phosphofructokinase 0.0115 0.1262 0.1258
Entamoeba histolytica hypothetical protein 0.0021 0.0178 0.1263
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0009 0.0039 0.0035
Schistosoma mansoni DNA-directed RNA polymerase III subunit 0.0013 0.0085 0.0085
Echinococcus multilocularis zinc finger protein 0.0009 0.0044 0.004
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0063 0.066 0.084
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0008 0.0025 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0006 0.0005 0.0005
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0344 0.1129
Echinococcus multilocularis ATPase family AAA domain containing protein 2B 0.0008 0.0025 0.002
Schistosoma mansoni hypothetical protein 0.0165 0.1844 0.1844
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0008 0.0025 0.0034
Brugia malayi Bromodomain containing protein 0.0008 0.0025 0.0031
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0226 0.0269
Brugia malayi PXA domain containing protein 0.0021 0.0178 0.027
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0178 0.0174
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0008 0.0025 0.002
Brugia malayi hypothetical protein 0.0021 0.0177 0.0268
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Trichomonas vaginalis DNA-directed RNA polymerase I subunit, putative 0.0013 0.0085 0.0242
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0226 0.0344
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0115 0.1262 0.1647
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0008 0.0025 0.002
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Onchocerca volvulus 0.0008 0.0025 0.0069
Echinococcus multilocularis bromodomain containing 2 0.0008 0.0025 0.002
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0226 0.0344
Schistosoma mansoni growth hormone secretagogue receptor 0.0006 0.0005 0.0005
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0185 0.0585
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0032
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0009 0.0044 0.004
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0008 0.0025 0.0032
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0162 0.0245
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0295 0.2811
Echinococcus granulosus expressed protein 0.0408 0.464 0.4638
Leishmania major RNA polymerase I second largest subunit, putative 0.0009 0.0043 0.0081
Mycobacterium ulcerans arylamine N-acetyltransferase Nat 0.0616 0.7051 0.926
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Brugia malayi DNA-directed RNA polymerase II second largest subunit, putative 0.0013 0.0085 0.0125
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.0178 0.027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0006 0.0005 0.0005
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Onchocerca volvulus Brd8 homolog 0.0008 0.0025 0.0069
Brugia malayi Intermediate filament tail domain containing protein 0.0056 0.058 0.0894
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0069 0.0178
Trypanosoma brucei hypothetical protein 0.024 0.2712 1
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0007 0.0022 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0088 0.0252
Brugia malayi follicle stimulating hormone receptor 0.0496 0.5664 0.8796
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0344 0.0339
Schistosoma mansoni histamine h1 receptor 0.0006 0.0005 0.0005
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0008 0.0032 0.0029
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0022 0.0016
Onchocerca volvulus 0.0092 0.0998 0.3395
Plasmodium falciparum DNA-directed RNA polymerase III subunit RPC2, putative 0.0013 0.0085 0.0084
Toxoplasma gondii hypothetical protein 0.0008 0.0025 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0032
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.1262 0.4281
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0463 0.1538
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0007 0.0022 0.0017
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0226 0.0759
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0008 0.0025 0.002
Schistosoma mansoni biogenic amine receptor 0.0006 0.0005 0.0005
Loa Loa (eye worm) phosphofructokinase 0.0115 0.1262 0.1955
Mycobacterium tuberculosis Probable sulfatase 0.0009 0.0045 0.0046
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0092 0.1 0.1547
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0177 0.0268
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0009 0.0044 0.004
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.0178 0.027
Mycobacterium ulcerans bacterioferritin BfrB 0.0008 0.0032 0.0014
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.0182 0.0177
Schistosoma mansoni biogenic amine (5HT) receptor 0.0006 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Entamoeba histolytica fatty acid elongase, putative 0.0086 0.0934 0.7351
Onchocerca volvulus 0.0056 0.058 0.1968
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Echinococcus multilocularis cpg binding protein 0.0032 0.0301 0.0296
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0039 0.0182
Echinococcus granulosus CREB binding protein 0.0008 0.0025 0.002
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0226 0.0269
Loa Loa (eye worm) hypothetical protein 0.0019 0.0153 0.023
Plasmodium vivax DNA-directed RNA polymerase I subunit RPA2, putative 0.0009 0.0043 0.0029
Schistosoma mansoni alpha-glucosidase 0.0137 0.1515 0.1515
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0006 0.0005 0.0005
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0015 0.00000000014512
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0295 0.036
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Brugia malayi Bromodomain containing protein 0.0008 0.0025 0.0031
Loa Loa (eye worm) hypothetical protein 0.0007 0.0022 0.0026
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.024 0.2712 1
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0344 0.1197
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0022 0.0016
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0247 0.0243
Loa Loa (eye worm) bromodomain containing protein 0.0008 0.0025 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0178 0.0561
Echinococcus granulosus protein kinase C binding protein 1 0.0008 0.0025 0.002
Mycobacterium ulcerans sulfatase 0.0009 0.0045 0.0031
Trypanosoma brucei Bromodomain, putative 0.0008 0.0025 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Echinococcus granulosus peregrin 0.0008 0.0025 0.002
Entamoeba histolytica fatty acid elongase, putative 0.0086 0.0934 0.7351
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Brugia malayi TAZ zinc finger family protein 0.0008 0.0025 0.0031
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Schistosoma mansoni bromodomain containing 0.0008 0.0025 0.0025
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0153 0.0173
Schistosoma mansoni opsin-like receptor 0.0006 0.0005 0.0005
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.0182 0.0275
Entamoeba histolytica hypothetical protein 0.0021 0.0178 0.1263
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.024 0.2712 1
Schistosoma mansoni ap endonuclease 0.002 0.0162 0.0162
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Loa Loa (eye worm) hypothetical protein 0.0021 0.0178 0.027
Trypanosoma cruzi bromodomain factor 2 protein 0.0008 0.0025 0.0012
Entamoeba histolytica bromodomain-containing protein 0.0008 0.0025 0.0025
Leishmania major DNA-binding protein, putative,predicted bromodomain protein 0.0008 0.0025 0.0012
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0178 0.0174
Brugia malayi DNA-directed RNA polymerase III subunit 127.6 kDa polypeptide 0.0013 0.0085 0.0125
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.0665 0.7613 1
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0295 0.0961
Trypanosoma brucei AAA ATPase, putative 0.0008 0.0025 0.0012
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0344 0.0527
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0178 0.0174
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.024 0.2712 1
Echinococcus granulosus lamin 0.0056 0.058 0.0576
Loa Loa (eye worm) hypothetical protein 0.0009 0.0039 0.0054
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0162 0.0507
Onchocerca volvulus Bile acid receptor homolog 0.0008 0.0025 0.0069
Trypanosoma brucei Bromodomain, putative 0.0008 0.0025 0.0012
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0058 0.061 0.0606
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0496 0.5664 0.8796
Schistosoma mansoni DNA-directed RNA polymerase I subunit 0.0009 0.0043 0.0043
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0092 0.0994 0.128
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0295 0.0961
Schistosoma mansoni steroid hormone receptor ad4bp 0.0008 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.0006 0.0005 0.0005
Entamoeba histolytica serine/threonine protein kinase, putative 0.0092 0.1 0.7886
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0006 0.0005 0.0005
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0088 0.0252
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0178 0.0174
Trypanosoma cruzi DNA-directed RNA polymerase III, putative 0.0013 0.0085 0.0237
Brugia malayi ATPase, AAA family protein 0.0008 0.0025 0.0031
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0006 0.0005 0.0005
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0021 0.0178 0.0561
Schistosoma mansoni retinoic acid receptor RXR 0.0008 0.0025 0.0025
Brugia malayi Bromodomain containing protein 0.0008 0.0025 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0008 0.0025 0.0032
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0022 0.0026
Trichomonas vaginalis set domain proteins, putative 0.0259 0.2929 1
Schistosoma mansoni amine GPCR 0.0006 0.0005 0.0005
Toxoplasma gondii bromodomain-containing protein 0.0008 0.0025 0.0033
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0006 0.0005 0.0005
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0295 0.0961
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0295 0.2202
Trypanosoma cruzi DNA-directed RNA polymerase II subunit 2, putative 0.0009 0.0035 0.0049
Schistosoma mansoni opsin-like receptor 0.0006 0.0005 0.0005
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0185 0.0585
Giardia lamblia Transcription regulatory protein SNF2 0.0008 0.0025 0.00000000043363
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.024 0.2712 1
Entamoeba histolytica fatty acid elongase, putative 0.0086 0.0934 0.7351
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0178 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0008 0.0032 0.0029
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.1262 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0031
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0007 0.0022 0.0016
Schistosoma mansoni kinase 0.0047 0.0477 0.0477
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0295 0.0961
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0141 0.0172
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0008 0.0025 0.0025
Echinococcus granulosus mixed lineage leukemia protein mll 0.0009 0.0036 0.0032
Brugia malayi phosphofructokinase 0.0115 0.1262 0.1955
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0008 0.0025 0.0032
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.032 0.032
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0022 0.0026
Trypanosoma cruzi bromodomain-containing protein 3 0.0008 0.0025 0.0012
Echinococcus granulosus bloom syndrome protein 0.0022 0.0185 0.0181
Trichomonas vaginalis ferritin, putative 0.0008 0.0032 0.006
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.1262 1
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.024 0.2712 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0162 0.0158
Schistosoma mansoni helicase 0.0008 0.0025 0.0025
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.1262 0.4281
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.1 0.1
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0185 0.0281
Giardia lamblia DNA-directed RNA polymerase RPB2 0.0013 0.0085 0.0621
Entamoeba histolytica DNA-directed RNA polymerase subunit, putative 0.0013 0.0085 0.0513
Echinococcus multilocularis polybromo 1 0.0008 0.0025 0.002
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0226 0.0759
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.1 0.3381
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.0178 0.0178
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0295 0.0943
Echinococcus granulosus PH interacting protein 0.0008 0.0025 0.002
Schistosoma mansoni neuropeptide receptor 0.0006 0.0005 0.0005
Echinococcus multilocularis ecdysone induced protein 78C 0.0008 0.0025 0.002
Leishmania major hypothetical protein, conserved 0.0008 0.0025 0.0012
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0682 0.0682
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.0182 0.0275
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0162 0.1135
Loa Loa (eye worm) hypothetical protein 0.0021 0.0178 0.027
Loa Loa (eye worm) DNA-directed RNA polymerase II second largest subunit 0.0013 0.0085 0.0125
Plasmodium falciparum DNA-directed RNA polymerase II subunit RPB2, putative 0.0013 0.0085 0.0084
Loa Loa (eye worm) RecQ helicase 0.0022 0.0185 0.0281
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Schistosoma mansoni ferritin light chain 0.0008 0.0032 0.0032
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.1262 0.1955
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0022 0.0016
Loa Loa (eye worm) hypothetical protein 0.0019 0.0153 0.023
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0031
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0031
Onchocerca volvulus 0.0021 0.0177 0.059
Schistosoma mansoni amine GPCR 0.0006 0.0005 0.0005
Brugia malayi Bromodomain containing protein 0.0009 0.0044 0.0062
Onchocerca volvulus 0.0007 0.0022 0.0058
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0178 0.0178
Brugia malayi hypothetical protein 0.0133 0.1471 0.2278
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0015 0.00000000014512
Echinococcus multilocularis Bromodomain containing protein 0.0008 0.0025 0.002
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0009 0.0036 0.0036
Schistosoma mansoni cpg binding protein 0.003 0.0281 0.0281
Loa Loa (eye worm) RNA polymerase III 128kD subunit-PA 0.0013 0.0085 0.0125
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0182 0.0182
Mycobacterium ulcerans arylsulfatase AtsD 0.0009 0.0045 0.0031
Onchocerca volvulus Serine\/threonine kinase homolog 0.0092 0.1 0.3404
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.1262 1
Loa Loa (eye worm) hypothetical protein 0.0056 0.058 0.0894
Schistosoma mansoni cpg binding protein 0.0032 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.0009 0.0044 0.0062
Loa Loa (eye worm) acetyltransferase 0.0311 0.3531 0.548
Toxoplasma gondii hypothetical protein 0.0045 0.0451 0.4417
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Mycobacterium tuberculosis Arylamine N-acetyltransferase Nat (arylamine acetylase) 0.0616 0.7051 0.9261
Trypanosoma cruzi Bromodomain, putative 0.0008 0.0025 0.0012
Loa Loa (eye worm) DNA-directed RNA polymerase 0.0011 0.0059 0.0084
Schistosoma mansoni thyroid hormone receptor 0.0008 0.0025 0.0025
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0006 0.0005 0.0005
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Brugia malayi NC domain containing protein 0.0045 0.0451 0.0694
Brugia malayi 6-phosphofructokinase 0.0115 0.1262 0.1955
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.032 0.032
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Brugia malayi small heat shock protein 0.0563 0.6439 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0228 0.2567 0.3982
Plasmodium vivax beta-ketoacyl-acyl carrier protein synthase III precursor, putative 0.0665 0.7613 1
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.1262 0.1262
Schistosoma mansoni hypothetical protein 0.0008 0.0025 0.0025
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.032 0.0316
Echinococcus granulosus bromodomain containing 2 0.0008 0.0025 0.002
Echinococcus granulosus bromodomain containing protein 8 0.0008 0.0025 0.002
Onchocerca volvulus 0.0008 0.0025 0.0069
Echinococcus granulosus ATPase family AAA domain containing protein 2B 0.0008 0.0025 0.002
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0006 0.0005 0.0005
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0008 0.0025 0.002
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0092 0.0994 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Echinococcus granulosus DNA directed RNA polymerase II subunit RPB2 0.0013 0.0085 0.0081
Trypanosoma brucei bromodomain factor 2 protein, putative 0.0008 0.0025 0.0012
Loa Loa (eye worm) hypothetical protein 0.0045 0.0451 0.0694
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0069 0.0386
Trichomonas vaginalis bromodomain containing protein, putative 0.0008 0.0025 0.0034
Brugia malayi CXXC zinc finger family protein 0.003 0.0281 0.043
Trichomonas vaginalis DNA-directed RNA polymerase III subunit, putative 0.0013 0.0085 0.0242
Loa Loa (eye worm) hypothetical protein 0.0008 0.0025 0.0032
Plasmodium vivax bromodomain protein, putative 0.0008 0.0025 0.0004
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Schistosoma mansoni alpha-glucosidase 0.0137 0.1515 0.1515
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0178 0.0174
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.1262 0.1262
Leishmania major ATP-dependent phosphofructokinase 0.0115 0.1262 0.4612
Schistosoma mansoni neuropeptide receptor 0.0006 0.0005 0.0005
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0006 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0063 0.066 0.066
Brugia malayi Bromodomain containing protein 0.0008 0.0025 0.0031
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Schistosoma mansoni polybromo-1 0.0008 0.0025 0.0025
Schistosoma mansoni opsin-like receptor 0.0006 0.0005 0.0005
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0088 0.0252
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0178 0.0178
Trypanosoma brucei glucosidase, putative 0.0035 0.0344 0.1197
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0009 0.0039 0.0035
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.1 0.3381
Echinococcus multilocularis Bromodomain containing protein 0.0008 0.0025 0.002
Trichomonas vaginalis maltase-glucoamylase, putative 0.0013 0.0088 0.0252
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Brugia malayi hypothetical protein 0.0021 0.0178 0.027
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.0665 0.7613 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0344 0.1129
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0008 0.0025 0.002
Loa Loa (eye worm) hypothetical protein 0.0009 0.0045 0.0062
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0344 0.1129
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0006 0.0005 0.0005
Brugia malayi PHD-finger family protein 0.0009 0.0044 0.0062
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0281 0.043
Loa Loa (eye worm) oxidoreductase 0.0007 0.0022 0.0026
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0178 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0045 0.0103
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0208 0.0316
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0141 0.0172
Mycobacterium leprae DNA-DIRECTED RNA POLYMERASE (BETA CHAIN) RPOB (TRANSCRIPTASE BETA CHAIN) (RNA POLYMERASE BETA SUBUNIT) 0.025 0.2818 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0344 0.1129
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Brugia malayi Nuclear hormone receptor-like 1 0.0008 0.0025 0.0032
Entamoeba histolytica fatty acid elongase, putative 0.0086 0.0934 0.7351
Brugia malayi bromodomain containing protein 0.0008 0.0025 0.0031
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0009 0.0038 0.0078
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.024 0.2712 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0344 0.2596
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0008 0.0025 0.0032
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0092 0.1 0.0996
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0069 0.0188
Schistosoma mansoni lipoxygenase 0.0058 0.061 0.061
Brugia malayi Bromodomain containing protein 0.0008 0.0025 0.0031
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0133 0.0133
Mycobacterium ulcerans 6-phosphofructokinase 0.0115 0.1262 0.1634
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0162 0.0186
Wolbachia endosymbiont of Brugia malayi DNA-directed RNA polymerase subunit beta/beta' 0.025 0.2818 0.3675
Entamoeba histolytica bromodomain-containing protein 0.0008 0.0025 0.0025
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0009 0.0039 0.0035
Plasmodium vivax DNA-directed RNA polymerase II subunit RPB2, putative 0.0013 0.0085 0.0084
Plasmodium falciparum histone acetyltransferase GCN5 0.0084 0.0906 0.1164
Echinococcus granulosus expressed protein 0.0008 0.0032 0.0027
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0008 0.0025 0.0069
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0092 0.1 0.3637
Plasmodium falciparum bromodomain protein 1 0.0008 0.0025 0.0004
Schistosoma mansoni z-protein (S1r protein) 0.0021 0.0178 0.0178
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0006 0.0005 0.0005
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0226 0.0269
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0022 0.0026
Entamoeba histolytica bromodomain-containing protein 0.0008 0.0025 0.0025
Onchocerca volvulus Protein ultraspiracle homolog 0.0008 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0021 0.0177 0.0268
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0025 0.0034
Schistosoma mansoni hypothetical protein 0.0021 0.0177 0.0177
Trichomonas vaginalis bromodomain and PHD finger-containing protein, putative 0.0008 0.0025 0.0034
Brugia malayi hypothetical protein 0.0021 0.0178 0.027
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.032 0.3074
Trichomonas vaginalis bromodomain containing protein, putative 0.0008 0.0025 0.0034
Schistosoma mansoni lipoxygenase 0.0021 0.0177 0.0177
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0226 0.1646
Brugia malayi intermediate filament protein 0.0056 0.058 0.0894
Schistosoma mansoni DNA-directed RNA polymerase III subunit 0.0013 0.0085 0.0085
Mycobacterium ulcerans hypothetical protein 0.0025 0.0226 0.0269
Schistosoma mansoni rab6-interacting 0.0021 0.0177 0.0177
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0008 0.0025 0.0032
Schistosoma mansoni hypothetical protein 0.0872 1 1
Entamoeba histolytica fatty acid elongase, putative 0.0086 0.0934 0.7351
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0295 0.0961
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0006 0.0005 0.0005
Brugia malayi PXA domain containing protein 0.0021 0.0178 0.027
Echinococcus granulosus FTZ F1 alpha 0.0008 0.0025 0.002
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0226 0.1646
Trichomonas vaginalis bromodomain-containing protein, putative 0.0008 0.0025 0.0034

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 29 uM Assayed against human skin fibroblast Collagenase using the spectrophotometric assay with the thiol ester substrate at pH 6.5. ChEMBL. 2153207

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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