Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | AGC kinase | 0.0282 | 0.0312 | 0.5 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0282 | 0.0312 | 0.0757 |
Onchocerca volvulus | 0.2019 | 0.8645 | 1 | |
Schistosoma mansoni | serine/threonine protein kinase | 0.0282 | 0.0312 | 0.0757 |
Trichomonas vaginalis | AGC family protein kinase | 0.0282 | 0.0312 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0282 | 0.0312 | 1 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0282 | 0.0312 | 0.0757 |
Entamoeba histolytica | protein kinase, putative | 0.0282 | 0.0312 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0282 | 0.0312 | 0.0757 |
Loa Loa (eye worm) | hypothetical protein | 0.0776 | 0.268 | 0.268 |
Schistosoma mansoni | atypical protein kinase C | 0.0481 | 0.1267 | 0.3072 |
Trichomonas vaginalis | AGC family protein kinase | 0.0282 | 0.0312 | 1 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0282 | 0.0312 | 0.0312 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0282 | 0.0312 | 0.0757 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0602 | 0.1847 | 0.1847 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0282 | 0.0312 | 0.0757 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1077 | 0.4123 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2019 | 0.8645 | 0.8645 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0577 | 0.1725 | 0.4185 |
Trichomonas vaginalis | AGC family protein kinase | 0.0282 | 0.0312 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.05 | 0.1355 | 0.3286 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0282 | 0.0312 | 0.0312 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0282 | 0.0312 | 0.0757 |
Trichomonas vaginalis | AGC family protein kinase | 0.0282 | 0.0312 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0282 | 0.0312 | 0.5 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0282 | 0.0312 | 0.0757 |
Echinococcus granulosus | protein kinase C gamma type | 0.0878 | 0.3168 | 0.7684 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0282 | 0.0312 | 0.0312 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0282 | 0.0312 | 0.0312 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0577 | 0.1725 | 0.4185 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0282 | 0.0312 | 0.0757 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0282 | 0.0312 | 0.0757 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0878 | 0.3168 | 0.7684 |
Entamoeba histolytica | protein kinase, putative | 0.0282 | 0.0312 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0282 | 0.0312 | 1 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.05 | 0.1355 | 0.3286 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0282 | 0.0312 | 0.0757 |
Echinococcus multilocularis | protein kinase c iota type | 0.0481 | 0.1267 | 0.3072 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0282 | 0.0312 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0577 | 0.1725 | 0.1725 |
Entamoeba histolytica | protein kinase, putative | 0.0282 | 0.0312 | 0.5 |
Brugia malayi | Protein kinase c protein 2 | 0.0801 | 0.2802 | 1 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.1077 | 0.4123 | 1 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0282 | 0.0312 | 0.0757 |
Schistosoma mansoni | serine/threonine kinase | 0.0282 | 0.0312 | 0.0757 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.05 | 0.1355 | 0.1355 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0282 | 0.0312 | 0.0757 |
Loa Loa (eye worm) | hypothetical protein | 0.2019 | 0.8645 | 0.8645 |
Trichomonas vaginalis | AGC family protein kinase | 0.0282 | 0.0312 | 1 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0282 | 0.0312 | 0.0312 |
Trichomonas vaginalis | AGC family protein kinase | 0.0282 | 0.0312 | 1 |
Echinococcus granulosus | protein kinase c epsilon type | 0.05 | 0.1355 | 0.3286 |
Echinococcus granulosus | protein kinase c iota type | 0.0481 | 0.1267 | 0.3072 |
Loa Loa (eye worm) | hypothetical protein | 0.2218 | 0.96 | 0.96 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.1077 | 0.4123 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0282 | 0.0312 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2019 | 0.8645 | 0.8645 |
Trichomonas vaginalis | AGC family protein kinase | 0.0282 | 0.0312 | 1 |
Echinococcus granulosus | NDR protein kinase | 0.0282 | 0.0312 | 0.0757 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0282 | 0.0312 | 0.0312 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0577 | 0.1725 | 0.4185 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1077 | 0.4123 | 1 |
Brugia malayi | protein kinase C II. | 0.05 | 0.1355 | 0.4188 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0282 | 0.0312 | 0.0757 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0282 | 0.0312 | 0.0312 |
Trichomonas vaginalis | AGC family protein kinase | 0.0282 | 0.0312 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.