Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Carboxylesterase family protein | 0.0368 | 0.4824 | 0.4824 |
Loa Loa (eye worm) | carboxylesterase | 0.0368 | 0.4824 | 0.4824 |
Echinococcus multilocularis | carbonic anhydrase II | 0.0404 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0368 | 0.4824 | 0.4824 |
Echinococcus granulosus | carboxylesterase 5A | 0.0368 | 0.4824 | 0.4824 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0404 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0368 | 0.4824 | 0.4824 |
Brugia malayi | Carboxylesterase family protein | 0.0368 | 0.4824 | 0.4824 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0404 | 1 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0368 | 0.4824 | 0.4824 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0404 | 1 | 1 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0404 | 1 | 1 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0404 | 1 | 0.5 |
Echinococcus granulosus | carbonic anhydrase II | 0.0404 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0368 | 0.4824 | 0.4824 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0404 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0368 | 0.4824 | 0.4824 |
Echinococcus multilocularis | acetylcholinesterase | 0.0368 | 0.4824 | 0.4824 |
Loa Loa (eye worm) | hypothetical protein | 0.0368 | 0.4824 | 0.4824 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.0404 | 1 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0368 | 0.4824 | 0.4824 |
Loa Loa (eye worm) | hypothetical protein | 0.0368 | 0.4824 | 0.4824 |
Leishmania major | carbonic anhydrase-like protein | 0.0404 | 1 | 0.5 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.0404 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.