Detailed information for compound 1750648

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 424.533 | Formula: C25H32N2O4
  • H donors: 0 H acceptors: 3 LogP: 2.44 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)[C@@]12CCC=C2N(C(=O)[C@@H](C1)CC(=O)N1CCCCC1)Cc1ccccc1
  • InChi: 1S/C25H32N2O4/c1-2-31-24(30)25-13-9-12-21(25)27(18-19-10-5-3-6-11-19)23(29)20(17-25)16-22(28)26-14-7-4-8-15-26/h3,5-6,10-12,20H,2,4,7-9,13-18H2,1H3/t20-,25+/m1/s1
  • InChiKey: JRAMSLVFHPWIHG-NLFFAJNJSA-N  


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Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0108 0.0166 0.0245
Trypanosoma brucei potassium voltage-gated channel, putative 0.0116 0.0186 0.23
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0108 0.0165 0.0216
Echinococcus granulosus BTB:POZ domain containing protein KCTD16 0.0116 0.0186 0.0274
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 0.0166 0.0245
Schistosoma mansoni hypothetical protein 0.0791 0.1927 0.2824
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0108 0.0165 0.0163
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0121 0.0198 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Schistosoma mansoni neuropeptide receptor 0.0674 0.1627 0.2379
Loa Loa (eye worm) latrophilin receptor protein 2 0.0791 0.1927 0.1925
Loa Loa (eye worm) K+ channel tetramerisation domain-containing protein 0.0116 0.0186 0.0184
Echinococcus multilocularis neuropeptides capa receptor 0.0108 0.0166 0.0245
Onchocerca volvulus 0.0108 0.0165 0.1577
Echinococcus granulosus voltage gated potassium channel 0.0225 0.0465 0.0687
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Brugia malayi voltage-dependent calcium channel 0.0108 0.0165 0.0163
Brugia malayi G-protein coupled receptor 0.0108 0.0166 0.0163
Loa Loa (eye worm) K+ channel tetramerisation domain-containing protein 0.0116 0.0186 0.0184
Onchocerca volvulus 0.0108 0.0166 0.1582
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0225 0.0465 0.0687
Schistosoma mansoni voltage-gated ion channel 0.0108 0.0165 0.0216
Onchocerca volvulus 0.0108 0.0166 0.1582
Onchocerca volvulus 0.0108 0.0166 0.1582
Trypanosoma brucei btb/poz domain containing protein, putative 0.0116 0.0186 0.23
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 0.0166 0.0217
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Echinococcus granulosus ryanodine receptor 44f 0.0108 0.0165 0.0244
Loa Loa (eye worm) voltage-gated potassium channel 0.0108 0.0165 0.0163
Loa Loa (eye worm) G-protein coupled receptor 0.0108 0.0166 0.0163
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0108 0.0166 0.0163
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0116 0.0186 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0108 0.0166 0.0217
Onchocerca volvulus Neuropeptide F receptor homolog 0.0108 0.0166 0.1582
Schistosoma mansoni biogenic amine receptor 0.0108 0.0166 0.0217
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0791 0.1927 0.2844
Echinococcus granulosus sex peptide receptor 0.0108 0.0166 0.0245
Plasmodium vivax merozoite adhesive erythrocytic binding protein 0.0073 0.0073 0.0245
Loa Loa (eye worm) hypothetical protein 0.0108 0.0165 0.0163
Onchocerca volvulus 0.0116 0.0186 0.1811
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0108 0.0166 0.0245
Echinococcus multilocularis transient receptor potential cation channel 0.0108 0.0165 0.0244
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0121 0.0198 1
Brugia malayi prolyl oligopeptidase family protein 0.0176 0.0339 0.0337
Brugia malayi neuropeptide F receptor 0.0108 0.0166 0.0163
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0108 0.0165 0.0244
Brugia malayi ORL1-like opioid receptor 0.0108 0.0166 0.0163
Schistosoma mansoni tyrosine kinase 0.0084 0.0102 0.0123
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Echinococcus multilocularis voltage dependent calcium channel 0.0108 0.0165 0.0244
Schistosoma mansoni transient receptor potential channel 0.0108 0.0165 0.0216
Echinococcus multilocularis BTB:POZ domain containing protein 0.0116 0.0186 0.0274
Echinococcus granulosus allatostatin A receptor 0.0108 0.0166 0.0245
Echinococcus granulosus calcium activated potassium channel 0.0108 0.0165 0.0244
Brugia malayi Protein kinase domain containing protein 0.0072 0.0072 0.007
Mycobacterium ulcerans 3-dehydroquinate dehydratase 0.1146 0.2844 0.5
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Brugia malayi cation channel family protein 0.0108 0.0165 0.0163
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 0.0166 0.0217
Schistosoma mansoni ryanodine receptor related 0.0108 0.0165 0.0216
Schistosoma mansoni growth hormone secretagogue receptor 0.0108 0.0166 0.0217
Leishmania major hypothetical protein, conserved 0.0108 0.0165 0.299
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0108 0.0165 0.0216
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0108 0.0165 0.0216
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Loa Loa (eye worm) TK/ROR protein kinase 0.0072 0.0072 0.007
Mycobacterium tuberculosis 3-dehydroquinate dehydratase AroD (AROQ) (3-dehydroquinase) (type II dhqase) 0.1146 0.2844 0.5
Loa Loa (eye worm) potassium channel tetramerisation domain containing 5 0.0116 0.0186 0.0184
Brugia malayi hypothetical protein 0.0108 0.0165 0.0163
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0121 0.0198 0.0292
Brugia malayi G-protein coupled receptor 0.0108 0.0166 0.0163
Brugia malayi neuropeptide F receptor 0.0108 0.0166 0.0163
Echinococcus granulosus orexin receptor type 2 0.0108 0.0166 0.0245
Loa Loa (eye worm) hypothetical protein 0.0108 0.0165 0.0163
Loa Loa (eye worm) voltage-gated calcium channel 0.0108 0.0165 0.0163
Brugia malayi ion channel NompC 0.0108 0.0165 0.0163
Echinococcus granulosus biogenic amine 5HT receptor 0.0108 0.0166 0.0245
Echinococcus granulosus voltage gated potassium channel 0.0108 0.0165 0.0244
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 0.0166 0.0245
Echinococcus multilocularis shaker cognate 0.0225 0.0465 0.0687
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0108 0.0166 0.0163
Loa Loa (eye worm) calcium channel 0.0108 0.0165 0.0163
Trypanosoma brucei btb/poz domain containing protein, putative 0.0116 0.0186 0.23
Echinococcus granulosus transient receptor potential cation channel 0.0108 0.0165 0.0244
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0108 0.0166 0.0245
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0108 0.0165 0.198
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0108 0.0166 0.0245
Trypanosoma brucei RNA helicase, putative 0.0308 0.068 1
Loa Loa (eye worm) neuropeptide F receptor 0.0108 0.0166 0.0163
Schistosoma mansoni adenoreceptor 0.0108 0.0166 0.0217
Echinococcus granulosus sodium leak channel non selective protein 0.0108 0.0165 0.0244
Echinococcus granulosus potassium voltage gated channel protein 0.0108 0.0165 0.0244
Trypanosoma brucei BTB/POZ domain/Regulator of chromosome condensation (RCC1) repeat, putative 0.0116 0.0186 0.23
Echinococcus multilocularis allatostatin A receptor 0.0108 0.0166 0.0245
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0108 0.0165 0.0216
Loa Loa (eye worm) hypothetical protein 0.0225 0.0465 0.0463
Echinococcus granulosus potassium voltage gated channel protein 0.2669 0.6776 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0108 0.0166 0.0163
Echinococcus granulosus voltage dependent calcium channel 0.0108 0.0165 0.0244
Schistosoma mansoni neuropeptide receptor 0.0108 0.0166 0.0217
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Plasmodium vivax apical membrane antigen 1 0.0308 0.068 1
Brugia malayi larval opioid receptor 0.0108 0.0166 0.0163
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0108 0.0165 0.0216
Brugia malayi Serotonin receptor 0.0108 0.0166 0.0163
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0108 0.0165 0.0244
Schistosoma mansoni amine GPCR 0.0108 0.0166 0.0217
Echinococcus granulosus transient receptor potential cation channel 0.0108 0.0165 0.0244
Mycobacterium leprae 3-dehydroquinate dehydratase AroD (AroQ) (3-dehydroquinase) (Type II DHQase) 0.1146 0.2844 0.5
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0108 0.0165 0.0163
Schistosoma mansoni neuropeptide F-like receptor 0.0108 0.0166 0.0217
Plasmodium vivax K+ channel tetramerisation domain containing protein 0.0116 0.0186 0.2055
Schistosoma mansoni opsin-like receptor 0.0108 0.0166 0.0217
Echinococcus granulosus rhodopsin orphan GPCR 0.0108 0.0166 0.0245
Echinococcus granulosus rhodopsin orphan GPCR 0.0108 0.0166 0.0245
Schistosoma mansoni hypothetical protein 0.0108 0.0166 0.0217
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0116 0.0186 1
Echinococcus multilocularis integrin alpha ps 0.0073 0.0075 0.011
Schistosoma mansoni tyrosine kinase 0.0084 0.0102 0.0123
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Echinococcus multilocularis g-protein coupled receptor 0.0108 0.0166 0.0245
Leishmania major hypothetical protein, conserved 0.0116 0.0186 0.3474
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0108 0.0165 0.1979
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0108 0.0165 0.0163
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0108 0.0166 0.0163
Brugia malayi hypothetical protein 0.0108 0.0166 0.0163
Toxoplasma gondii K+ channel tetramerisation domain-containing protein 0.0116 0.0186 0.23
Loa Loa (eye worm) hypothetical protein 0.0108 0.0165 0.0163
Echinococcus multilocularis insulin receptor 0.0052 0.0019 0.0028
Echinococcus granulosus transient receptor potential cation channel 0.0108 0.0165 0.0244
Leishmania major potassium voltage-gated channel, putative 0.0116 0.0186 0.3474
Echinococcus multilocularis neuropeptide FF receptor 2 0.0108 0.0166 0.0245
Echinococcus granulosus peptide allatostatin:somatostatin 0.0108 0.0166 0.0245
Loa Loa (eye worm) hypothetical protein 0.0128 0.0217 0.0215
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 0.0166 0.0217
Brugia malayi hypothetical protein 0.0108 0.0166 0.0163
Brugia malayi hypothetical protein 0.0108 0.0166 0.0163
Loa Loa (eye worm) hypothetical protein 0.0108 0.0165 0.0163
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0108 0.0166 0.0217
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Echinococcus multilocularis neuropeptide receptor A26 0.0606 0.1449 0.2139
Toxoplasma gondii kelch repeat and K+ channel tetramerisation domain containing protein 0.0116 0.0186 0.23
Echinococcus multilocularis GPCR, family 2 0.0791 0.1927 0.2844
Plasmodium falciparum membrane associated erythrocyte binding-like protein 0.0073 0.0073 0.0245
Echinococcus granulosus rhodopsin orphan GPCR 0.0108 0.0166 0.0245
Schistosoma mansoni alpha-1 adrenergic receptor 0.0108 0.0166 0.0217
Schistosoma mansoni voltage-gated potassium channel 0.2669 0.6776 1
Echinococcus granulosus hyperpolarization activated cyclic 0.0108 0.0165 0.0244
Echinococcus granulosus g protein coupled receptor 0.0108 0.0166 0.0245
Loa Loa (eye worm) hypothetical protein 0.0067 0.0058 0.0056
Echinococcus granulosus dro:myosuppressin receptor 0.0108 0.0166 0.0245
Schistosoma mansoni opsin-like receptor 0.0108 0.0166 0.0217
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0791 0.1927 0.1925
Brugia malayi Dopamine receptor 0.0108 0.0166 0.0163
Brugia malayi solute carrier family 40, member 1 0.0395 0.0905 0.0903
Echinococcus multilocularis transient receptor potential cation channel 0.0108 0.0165 0.0244
Echinococcus multilocularis sodium leak channel non selective protein 0.0108 0.0165 0.0244
Schistosoma mansoni voltage-gated potassium channel 0.0225 0.0465 0.066
Schistosoma mansoni edp1-related 0.0116 0.0186 0.0247
Brugia malayi Serotonin receptor 0.0108 0.0166 0.0163
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 0.0166 0.0217
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0108 0.0166 0.0245
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.2669 0.6776 0.6775
Plasmodium falciparum kelch protein K13 0.0116 0.0186 0.2055
Plasmodium falciparum membrane associated erythrocyte binding-like protein 0.0073 0.0073 0.0245
Echinococcus granulosus neuropeptide s receptor 0.0606 0.1449 0.2139
Echinococcus multilocularis neuropeptide receptor 0.0108 0.0166 0.0245
Toxoplasma gondii hypothetical protein 0.0108 0.0165 0.1979
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Echinococcus multilocularis somatostatin receptor 0.0108 0.0166 0.0245
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0108 0.0165 0.0244
Echinococcus multilocularis sex peptide receptor 0.0108 0.0166 0.0245
Toxoplasma gondii apical membrane antigen 1 domain-containing protein 0.0308 0.068 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0055 0.0027 0.0024
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 0.0166 0.0245
Schistosoma mansoni opsin-like receptor 0.0108 0.0166 0.0217
Echinococcus granulosus neuropeptides capa receptor 0.0108 0.0166 0.0245
Echinococcus granulosus epidermal growth factor receptor 0.0084 0.0102 0.015
Echinococcus multilocularis serotonin receptor 0.0108 0.0166 0.0245
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0165 0.0216
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 0.0166 0.0245
Echinococcus granulosus alpha 1A adrenergic receptor 0.0108 0.0166 0.0245
Brugia malayi Protein kinase domain containing protein 0.0052 0.0019 0.0017
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0116 0.0186 1
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0165 0.0216
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0108 0.0166 0.0245
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0108 0.0166 0.0163
Schistosoma mansoni hypothetical protein 0.0308 0.068 0.0978
Echinococcus multilocularis orexin receptor type 2 0.0108 0.0166 0.0245
Echinococcus granulosus GPCR family 2 0.0791 0.1927 0.2844
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Brugia malayi cation channel family protein 0.0108 0.0165 0.0163
Echinococcus multilocularis neuropeptide Y receptor 0.0108 0.0166 0.0245
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0108 0.0165 0.0244
Loa Loa (eye worm) hypothetical protein 0.0124 0.0205 0.0203
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Onchocerca volvulus 0.0067 0.0058 0.0357
Loa Loa (eye worm) hypothetical protein 0.0108 0.0165 0.0163
Schistosoma mansoni hypothetical protein 0.0791 0.1927 0.2824
Loa Loa (eye worm) hypothetical protein 0.009 0.0118 0.0116
Loa Loa (eye worm) hypothetical protein 0.0108 0.0165 0.0163
Echinococcus multilocularis transient receptor potential cation channel 0.0108 0.0165 0.0244
Onchocerca volvulus 0.0116 0.0186 0.1811
Brugia malayi GnHR receptor homolog 0.0108 0.0166 0.0163
Echinococcus multilocularis serotonin receptor 0.0108 0.0166 0.0245
Echinococcus granulosus tm gpcr rhodopsin 0.0108 0.0166 0.0245
Brugia malayi Voltage-gated potassium channel, Shal-family (KCND, Kv4-like) alpha-subunit. C. elegans shl-1 ortholog 0.0116 0.0186 0.0184
Loa Loa (eye worm) hypothetical protein 0.0105 0.0157 0.0155
Loa Loa (eye worm) hypothetical protein 0.0108 0.0165 0.0163
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0108 0.0166 0.0217
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 0.0166 0.0217
Loa Loa (eye worm) Kv4.2 voltage-gated potassium channel 0.0116 0.0186 0.0184
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0108 0.0165 0.1577
Echinococcus granulosus neuropeptides capa receptor 0.0108 0.0166 0.0245
Echinococcus granulosus protein tyrosine kinase 0.0598 0.1429 0.2109
Onchocerca volvulus 0.0108 0.0166 0.1582
Loa Loa (eye worm) hypothetical protein 0.0121 0.0198 0.0196
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0108 0.0165 0.0216
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Loa Loa (eye worm) hypothetical protein 0.0108 0.0165 0.0163
Echinococcus multilocularis hyperpolarization activated cyclic 0.0108 0.0165 0.0244
Echinococcus multilocularis receptor type guanylyl cyclase 0.0055 0.0027 0.0039
Schistosoma mansoni tyrosine kinase 0.0152 0.0278 0.0383
Onchocerca volvulus 0.0108 0.0166 0.1582
Toxoplasma gondii apical membrane antigen 1 protein 0.0073 0.0073 0.0545
Schistosoma mansoni potassium channel tetramerization domain-containing 0.0116 0.0186 0.0247
Brugia malayi RE15519p 0.0108 0.0166 0.0163
Echinococcus granulosus BTB:POZ domain containing protein 0.0116 0.0186 0.0274
Echinococcus multilocularis transient receptor potential cation channel 0.0108 0.0165 0.0244
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Schistosoma mansoni hypothetical protein 0.0108 0.0165 0.0216
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0165 0.0216
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0108 0.0166 0.0245
Brugia malayi K+ channel tetramerisation domain containing protein 0.0116 0.0186 0.0184
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0108 0.0166 0.0245
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0108 0.0165 0.0163
Loa Loa (eye worm) hypothetical protein 0.0108 0.0165 0.0163
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0108 0.0166 0.0163
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0108 0.0166 0.0217
Schistosoma mansoni hypothetical protein 0.0791 0.1927 0.2824
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0108 0.0166 0.0245
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Loa Loa (eye worm) hypothetical protein 0.0108 0.0165 0.0163
Echinococcus multilocularis G protein coupled receptor 139 0.0674 0.1627 0.2401
Brugia malayi Dopamine receptor protein 1 0.0108 0.0166 0.0163
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0108 0.0165 0.0244
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0108 0.0166 0.0245
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0124 0.0205 0.0203
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0108 0.0165 0.0163
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0108 0.0165 0.8606
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 0.0166 0.0245
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0084 0.0102 0.015
Schistosoma mansoni transient receptor potential channel 4 0.0108 0.0165 0.0216
Schistosoma mansoni serine-type protease inhibitor 0.1792 0.4511 0.6648
Schistosoma mansoni biogenic amine receptor 0.0108 0.0166 0.0217
Loa Loa (eye worm) hypothetical protein 0.0116 0.0186 0.0184
Echinococcus granulosus shaker cognate 0.0225 0.0465 0.0687
Loa Loa (eye worm) hypothetical protein 0.0108 0.0165 0.0163
Schistosoma mansoni hypothetical protein 0.0108 0.0166 0.0217
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0108 0.0166 0.0217
Brugia malayi hypothetical protein 0.0108 0.0166 0.0163
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Echinococcus multilocularis neuropeptide Y receptor 0.0108 0.0166 0.0245
Echinococcus granulosus TRP transient receptor potential channel 0.0108 0.0165 0.0244
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Trypanosoma cruzi potassium voltage-gated channel 0.0116 0.0186 1
Brugia malayi Dopamine receptor protein 2 0.0108 0.0166 0.0163
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 0.0166 0.0217
Loa Loa (eye worm) hypothetical protein 0.0108 0.0165 0.0163
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0165 0.0216
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0108 0.0166 0.0245
Echinococcus granulosus g-protein coupled receptor 0.0108 0.0166 0.0245
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0108 0.0165 0.0216
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0108 0.0165 0.0216
Loa Loa (eye worm) hypothetical protein 0.0108 0.0165 0.0163
Echinococcus multilocularis epidermal growth factor receptor 0.0152 0.0278 0.041
Brugia malayi prolyl oligopeptidase family protein 0.0059 0.0038 0.0036
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0116 0.0186 1
Echinococcus granulosus hyperpolarization activated cyclic 0.0108 0.0165 0.0244
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0108 0.0165 0.0163
Echinococcus granulosus voltage gated hydrogen channel 1 0.0108 0.0165 0.0244
Loa Loa (eye worm) integrin alpha pat-2 0.0252 0.0536 0.0534
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0108 0.0166 0.0217
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0108 0.0165 0.0216
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0108 0.0165 0.0244
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0108 0.0166 0.0245
Loa Loa (eye worm) TK/FAK protein kinase 0.0605 0.1447 0.1445
Loa Loa (eye worm) G-protein coupled receptor 0.0108 0.0166 0.0163
Brugia malayi Protein kinase domain containing protein 0.0605 0.1447 0.1445
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 0.0166 0.0245
Echinococcus granulosus epidermal growth factor receptor 0.0152 0.0278 0.041
Schistosoma mansoni voltage-gated potassium channel 0.0225 0.0465 0.066
Echinococcus granulosus short transient receptor potential channel 6 0.0108 0.0165 0.0244
Echinococcus granulosus G protein coupled receptor 139 0.0108 0.0166 0.0245
Echinococcus multilocularis neuropeptides capa receptor 0.0108 0.0166 0.0245
Onchocerca volvulus 0.0108 0.0166 0.1582
Schistosoma mansoni voltage-gated cation channel 0.0108 0.0165 0.0216
Onchocerca volvulus 0.0116 0.0186 0.1811
Echinococcus multilocularis BTB:POZ domain containing protein KCTD16 0.0116 0.0186 0.0274
Brugia malayi K+ channel tetramerisation domain containing protein 0.0116 0.0186 0.0184
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0108 0.0165 0.0244
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0052 0.0019 0.0028
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0176 0.0339 0.0501
Schistosoma mansoni voltage-gated potassium channel 0.2669 0.6776 1
Echinococcus granulosus hypothetical protein 0.0108 0.0165 0.0244
Loa Loa (eye worm) ion channel NompC 0.0108 0.0165 0.0163
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Brugia malayi Melatonin receptor type 1A 0.0108 0.0166 0.0163
Echinococcus granulosus 7TM GPCR rhodopsin 0.0108 0.0166 0.0245
Echinococcus multilocularis voltage gated potassium channel 0.0225 0.0465 0.0687
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0108 0.0165 0.0244
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0225 0.0465 0.0687
Schistosoma mansoni vesicular amine transporter 0.0225 0.0465 0.066
Loa Loa (eye worm) hypothetical protein 0.0116 0.0186 0.0184
Onchocerca volvulus 0.0108 0.0166 0.1582
Schistosoma mansoni myosin xvIII 0.0108 0.0166 0.0217
Echinococcus granulosus two pore calcium channel protein 2 0.0108 0.0165 0.0244
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0165 0.0216
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0176 0.0339 0.3561
Schistosoma mansoni tyrosine kinase 0.0078 0.0088 0.0102
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0165 0.0216
Echinococcus multilocularis voltage dependent calcium channel 0.0108 0.0165 0.0244
Brugia malayi hypothetical protein 0.0108 0.0166 0.0163
Leishmania major hypothetical protein, conserved 0.0116 0.0186 0.3474
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.3269 0.8323 0.8323
Brugia malayi hypothetical protein 0.0108 0.0166 0.0163
Brugia malayi Cyclic-nucleotide gated cation channel 0.0108 0.0165 0.0163
Trypanosoma brucei btb/poz domain containing protein, putative 0.0116 0.0186 0.23
Schistosoma mansoni transient receptor potential channel 0.0108 0.0165 0.0216
Echinococcus multilocularis potassium large conductance calcium activated 0.0108 0.0165 0.0244
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0108 0.0166 0.0245
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Schistosoma mansoni hypothetical protein 0.1675 0.421 0.6203
Onchocerca volvulus 0.0395 0.0905 1
Echinococcus multilocularis potassium voltage gated channel protein 0.2669 0.6776 1
Echinococcus multilocularis potassium voltage gated channel protein 0.0225 0.0465 0.0687
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0108 0.0165 0.0163
Leishmania major hypothetical protein, conserved 0.0116 0.0186 0.3474
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0999 0.2465 0.3638
Echinococcus granulosus tm gpcr rhodopsin 0.0108 0.0166 0.0245
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0108 0.0165 0.8606
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.2553 0.6476 0.9557
Plasmodium vivax kelch protein K13, putative 0.0116 0.0186 0.2055
Echinococcus granulosus potassium voltage gated channel protein 0.0225 0.0465 0.0687
Brugia malayi Receptor family ligand binding region containing protein 0.0055 0.0027 0.0024
Trypanosoma brucei btb/poz domain containing protein, putative 0.0116 0.0186 0.23
Leishmania major hypothetical protein, unknown function 0.0108 0.0165 0.299
Echinococcus granulosus Dipeptidyl peptidase 9 0.0059 0.0038 0.0056
Loa Loa (eye worm) TK/EGFR protein kinase 0.0152 0.0278 0.0276
Brugia malayi hypothetical protein 0.0108 0.0166 0.0163
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Brugia malayi Kringle domain containing protein 0.0067 0.0058 0.0056
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0108 0.0165 0.0244
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0791 0.1927 0.2844
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0108 0.0165 0.0163
Brugia malayi putative neuropeptide receptor NPR1 0.0108 0.0166 0.0163
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0116 0.0186 0.2055
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0121 0.0198 1
Echinococcus granulosus tissue type plasminogen activator 0.0067 0.0058 0.0086
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0059 0.0038 0.0028
Echinococcus multilocularis g protein coupled receptor 0.0108 0.0166 0.0245
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0108 0.0165 0.0216
Echinococcus multilocularis transient receptor potential gamma protein 0.0108 0.0165 0.0244
Onchocerca volvulus 0.0108 0.0166 0.1582
Echinococcus granulosus potassium voltage gated channel protein 0.0108 0.0165 0.0244
Loa Loa (eye worm) pigment dispersing factor receptor c 0.3919 1 1
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Schistosoma mansoni chromatin regulatory protein sir2 0.0121 0.0198 0.0265
Onchocerca volvulus 0.0108 0.0166 0.1582
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 0.0166 0.0245
Schistosoma mansoni biogenic amine (5HT) receptor 0.0108 0.0166 0.0217
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0108 0.0166 0.0245
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0108 0.0166 0.1582
Echinococcus multilocularis g protein coupled receptor 0.0108 0.0166 0.0245
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0116 0.0186 1
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0121 0.0198 0.0292
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0108 0.0165 0.0244
Brugia malayi Latrophilin receptor protein 2 0.0791 0.1927 0.1925
Brugia malayi AKH receptor 0.0108 0.0166 0.0163
Onchocerca volvulus 0.0108 0.0166 0.1582
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Echinococcus multilocularis transient receptor potential cation channel 0.0108 0.0165 0.0244
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0108 0.0165 0.0163
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0108 0.0165 0.0163
Loa Loa (eye worm) hypothetical protein 0.0791 0.1927 0.1925
Toxoplasma gondii hypothetical protein 0.0108 0.0165 0.1979
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0108 0.0165 0.0244
Onchocerca volvulus 0.0108 0.0166 0.1582
Loa Loa (eye worm) K+ channel tetramerisation domain-containing protein 0.0116 0.0186 0.0184
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 0.0166 0.0217
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0225 0.0465 0.0687
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0108 0.0166 0.0217
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0108 0.0165 0.0244
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0121 0.0198 0.5
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0108 0.0165 0.0163
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0108 0.0166 0.0217
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0108 0.0166 0.0163
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0108 0.0165 0.0163
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0108 0.0166 0.0245
Schistosoma mansoni voltage-gated potassium channel 0.0116 0.0186 0.0247
Echinococcus multilocularis protein tyrosine kinase 0.0598 0.1429 0.2109
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Schistosoma mansoni hypothetical protein 0.0791 0.1927 0.2824
Echinococcus multilocularis ryanodine receptor 44f 0.0108 0.0165 0.0244
Echinococcus granulosus 7tm_1 domain containing protein 0.0108 0.0166 0.0245
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 0.0166 0.0217
Echinococcus granulosus hypothetical protein 0.0108 0.0166 0.0245
Echinococcus granulosus potassium voltage gated channel protein 0.0225 0.0465 0.0687
Loa Loa (eye worm) voltage-dependent calcium channel 0.0108 0.0165 0.0163
Echinococcus granulosus somatostatin receptor 0.0108 0.0166 0.0245
Loa Loa (eye worm) hypothetical protein 0.0108 0.0165 0.0163
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0225 0.0465 0.0687
Toxoplasma gondii kringle domain-containing protein 0.0067 0.0058 0.0308
Schistosoma mansoni neuropeptide receptor 0.0108 0.0166 0.0217
Trypanosoma cruzi potassium voltage-gated channel, putative 0.0116 0.0186 1
Onchocerca volvulus 0.0108 0.0166 0.1582
Echinococcus granulosus insulin receptor 0.0052 0.0019 0.0028
Trypanosoma brucei potassium voltage-gated channel, putative 0.0116 0.0186 0.23
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0108 0.0165 0.0244
Loa Loa (eye worm) hypothetical protein 0.0395 0.0905 0.0903
Brugia malayi K+ channel tetramerisation domain containing protein 0.0116 0.0186 0.0184
Leishmania major hypothetical protein, conserved 0.0067 0.0058 0.0465
Trypanosoma cruzi hypothetical protein, conserved 0.0067 0.0058 0.1338
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0108 0.0165 0.0244
Loa Loa (eye worm) hypothetical protein 0.2669 0.6776 0.6775
Brugia malayi putative neuropeptide receptor 0.0108 0.0166 0.0163
Loa Loa (eye worm) hypothetical protein 0.0108 0.0165 0.0163
Loa Loa (eye worm) prolyl oligopeptidase 0.0176 0.0339 0.0337
Schistosoma mansoni 60S ribosomal protein L21 0.0108 0.0165 0.0216
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0108 0.0166 0.0245
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0108 0.0166 0.0163
Brugia malayi Transient-receptor-potential like protein 0.0108 0.0165 0.0163
Schistosoma mansoni amine GPCR 0.0108 0.0166 0.0217
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0059 0.0038 0.0056
Schistosoma mansoni hypothetical protein 0.0067 0.0058 0.0058
Brugia malayi mKIAA0176 protein 0.0116 0.0186 0.0184
Brugia malayi Furin-like cysteine rich region family protein 0.0152 0.0278 0.0276
Brugia malayi sulfakinin receptor protein 0.0108 0.0166 0.0163
Loa Loa (eye worm) hypothetical protein 0.1675 0.421 0.4209
Echinococcus multilocularis hyperpolarization activated cyclic 0.0108 0.0165 0.0244
Echinococcus granulosus tm gpcr rhodopsin 0.0108 0.0166 0.0245
Echinococcus multilocularis conserved hypothetical protein 0.0108 0.0165 0.0244
Schistosoma mansoni voltage-gated potassium channel 0.0225 0.0465 0.066
Schistosoma mansoni voltage-gated potassium channel 0.0225 0.0465 0.066
Echinococcus granulosus transient receptor potential cation channel 0.0108 0.0165 0.0244
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0165 0.0216
Echinococcus multilocularis sodium channel protein 0.0224 0.0463 0.0683
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0116 0.0186 1
Loa Loa (eye worm) neuropeptide F receptor 0.0108 0.0166 0.0163
Echinococcus granulosus integrin alpha ps 0.0073 0.0075 0.011
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0108 0.0165 0.0244
Schistosoma mansoni transient receptor potential channel 0.0108 0.0165 0.0216
Onchocerca volvulus 0.0108 0.0166 0.1582
Echinococcus multilocularis calcium activated potassium channel 0.0108 0.0165 0.0244
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0108 0.0165 0.0244
Brugia malayi Integrin alpha pat-2 precursor 0.0163 0.0308 0.0305
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0108 0.0165 0.0216
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0108 0.0166 0.0217
Schistosoma mansoni integrin alpha-ps 0.0073 0.0075 0.0083
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0108 0.0165 0.1577
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0176 0.0339 0.0501
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0108 0.0165 0.0244
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Echinococcus multilocularis fmrfamide receptor 0.0108 0.0166 0.0245
Schistosoma mansoni voltage-gated potassium channel 0.0225 0.0465 0.066
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0165 0.0216
Echinococcus multilocularis neuropeptide s receptor 0.0606 0.1449 0.2139
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0225 0.0465 0.0463
Schistosoma mansoni integrin alpha 0.0163 0.0308 0.0427
Echinococcus multilocularis G-protein coupled receptor, putative 0.0108 0.0166 0.0245
Brugia malayi follicle stimulating hormone receptor 0.0108 0.0166 0.0163
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0108 0.0165 0.0216
Echinococcus multilocularis g protein coupled receptor 0.0108 0.0166 0.0245
Echinococcus granulosus rhodopsin orphan GPCR 0.0108 0.0166 0.0245
Toxoplasma gondii apical membrane antigen AMA1 0.0073 0.0073 0.0545
Echinococcus multilocularis epidermal growth factor receptor 0.0084 0.0102 0.015
Loa Loa (eye worm) hypothetical protein 0.0116 0.0186 0.0184
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0108 0.0166 0.0163
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Schistosoma mansoni biogenic amine (5HT) receptor 0.0108 0.0166 0.0217
Schistosoma mansoni protein kinase 0.0055 0.0027 0.0011
Onchocerca volvulus 0.0116 0.0186 0.1811
Brugia malayi hypothetical protein 0.0108 0.0166 0.0163
Onchocerca volvulus 0.0108 0.0166 0.1582
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.1593 0.3999 0.5901
Echinococcus granulosus biogenic amine 5HT receptor 0.0108 0.0166 0.0245
Schistosoma mansoni serine-type protease inhibitor 0.1792 0.4511 0.6648
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0108 0.0165 0.0163
Echinococcus multilocularis potassium voltage gated channel protein 0.0108 0.0165 0.0244
Echinococcus multilocularis integrin alpha 3 0.0125 0.0209 0.0309
Schistosoma mansoni hypothetical protein 0.0108 0.0166 0.0217
Schistosoma mansoni neuropeptide F-like receptor 0.0108 0.0166 0.0217
Echinococcus granulosus potassium large conductance calcium activated 0.0108 0.0165 0.0244
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0225 0.0465 0.0687
Trypanosoma cruzi hypothetical protein, conserved 0.0116 0.0186 1
Echinococcus multilocularis integrin alpha ps 0.0073 0.0075 0.011
Onchocerca volvulus 0.0108 0.0166 0.1582
Echinococcus granulosus neuropeptide receptor A26 0.0606 0.1449 0.2139
Schistosoma mansoni biogenic amine receptor 0.0108 0.0166 0.0217
Schistosoma mansoni amine GPCR 0.0108 0.0166 0.0217
Brugia malayi latrophilin 2 splice variant baaae 0.1675 0.421 0.4209
Onchocerca volvulus 0.0116 0.0186 0.1811
Loa Loa (eye worm) RGC/RGC protein kinase 0.0055 0.0027 0.0024
Echinococcus multilocularis short transient receptor potential channel 6 0.0108 0.0165 0.0244
Echinococcus multilocularis transient receptor potential cation channel 0.0108 0.0165 0.0244
Loa Loa (eye worm) TK/INSR protein kinase 0.0052 0.0019 0.0017
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Echinococcus granulosus sodium channel protein 0.0224 0.0463 0.0683
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0108 0.0166 0.0217
Echinococcus multilocularis tissue type plasminogen activator 0.0067 0.0058 0.0086
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Echinococcus granulosus transient receptor potential gamma protein 0.0108 0.0165 0.0244
Schistosoma mansoni histamine h1 receptor 0.0108 0.0166 0.0217
Echinococcus multilocularis two pore calcium channel protein 1 0.0108 0.0165 0.0244
Onchocerca volvulus 0.0108 0.0166 0.1582
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0108 0.0165 0.0244
Schistosoma mansoni amine GPCR 0.0108 0.0166 0.0217
Loa Loa (eye worm) TYRA-2 protein 0.0108 0.0166 0.0163
Brugia malayi Tachykinin-like peptides receptor 99D 0.0108 0.0166 0.0163
Echinococcus granulosus serotonin receptor 0.0108 0.0166 0.0245
Schistosoma mansoni tyrosine kinase 0.0078 0.0088 0.0102
Echinococcus multilocularis neuropeptide receptor 0.0674 0.1627 0.2401
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Echinococcus granulosus rhodopsin orphan GPCR 0.0108 0.0166 0.0245
Echinococcus granulosus short transient receptor potential channel 6 0.0108 0.0165 0.0244
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0108 0.0165 0.0244
Echinococcus granulosus neuropeptide receptor 0.0674 0.1627 0.2401
Echinococcus granulosus rhodopsin orphan GPCR 0.0108 0.0166 0.0245
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0108 0.0165 0.0163
Echinococcus multilocularis fmrfamide receptor 0.0108 0.0166 0.0245
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0116 0.0186 0.0247
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0108 0.0165 0.0216
Toxoplasma gondii transporter, cation channel family protein 0.0108 0.0165 0.1979
Loa Loa (eye worm) ryanodine receptor 0.0108 0.0165 0.0163
Brugia malayi G protein-coupled receptor 0.0108 0.0166 0.0163
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0108 0.0165 0.0244
Echinococcus granulosus fmrfamide receptor 0.0108 0.0166 0.0245
Loa Loa (eye worm) voltage-gated potassium channel 0.0225 0.0465 0.0463
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0224 0.0463 0.0683
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Echinococcus granulosus voltage dependent calcium channel 0.0108 0.0165 0.0244
Brugia malayi olfactory channel protein osm-9 0.0108 0.0165 0.0163
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Schistosoma mansoni calcium-activated potassium channel 0.0108 0.0165 0.0216
Echinococcus multilocularis potassium voltage gated channel protein 0.0225 0.0465 0.0687
Echinococcus granulosus rhodopsin orphan GPCR 0.0108 0.0166 0.0245
Loa Loa (eye worm) hypothetical protein 0.0108 0.0165 0.0163
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0108 0.0165 0.0216
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0108 0.0166 0.0245
Brugia malayi NAD-dependent deacetylase SIRT1 0.0121 0.0198 0.0196
Brugia malayi K+ channel tetramerisation domain containing protein 0.0116 0.0186 0.0184
Echinococcus multilocularis two pore calcium channel protein 2 0.0108 0.0165 0.0244
Echinococcus granulosus transient receptor potential cation channel 0.0108 0.0165 0.0244
Schistosoma mansoni voltage-dependent calcium channel 0.0108 0.0165 0.0216
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0108 0.0166 0.0217
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0108 0.0165 0.0244
Echinococcus multilocularis dro:myosuppressin receptor 0.0108 0.0166 0.0245
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0108 0.0165 0.0216
Echinococcus granulosus neuropeptide receptor 0.0108 0.0166 0.0245
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0165 0.0216
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0108 0.0165 0.0216
Echinococcus granulosus two pore calcium channel protein 1 0.0108 0.0165 0.0244
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0225 0.0465 0.0687
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0108 0.0166 0.0245
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0108 0.0166 0.0217
Echinococcus granulosus neuropeptide Y receptor 0.0108 0.0166 0.0245
Echinococcus granulosus tachykinin peptides receptor 99D 0.0999 0.2465 0.3638
Loa Loa (eye worm) potassium channel tetramerisation domain containing 3 0.0116 0.0186 0.0184
Loa Loa (eye worm) hypothetical protein 0.0108 0.0165 0.0163
Loa Loa (eye worm) hypothetical protein 0.3269 0.8323 0.8323
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0176 0.0339 0.0474
Loa Loa (eye worm) hypothetical protein 0.0108 0.0165 0.0163
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0108 0.0166 0.0163
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0108 0.0165 0.0244
Schistosoma mansoni neuropeptide receptor 0.0108 0.0166 0.0217
Echinococcus granulosus neuropeptide Y receptor 0.0108 0.0166 0.0245
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0108 0.0165 0.1979
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0108 0.0166 0.0163
Echinococcus granulosus g protein coupled receptor 0.0108 0.0166 0.0245
Schistosoma mansoni hypothetical protein 0.0108 0.0166 0.0217
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0108 0.0165 0.198
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.1593 0.3999 0.5901
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0108 0.0166 0.0217
Echinococcus multilocularis 0.0046 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0108 0.0166 0.0163
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0225 0.0465 0.0687
Schistosoma mansoni tyrosine kinase 0.0598 0.1429 0.2087
Schistosoma mansoni voltage-gated potassium channel 0.0225 0.0465 0.066
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0108 0.0165 0.0216
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0108 0.0166 0.0217
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0121 0.0198 1
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0224 0.0463 1
Echinococcus multilocularis short transient receptor potential channel 6 0.0108 0.0165 0.0244
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0165 0.0216
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0108 0.0165 0.0244
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0108 0.0166 0.0217
Echinococcus granulosus integrin alpha 3 0.0125 0.0209 0.0309
Schistosoma mansoni voltage-gated potassium channel 0.0116 0.0186 0.0247
Schistosoma mansoni tyrosine kinase 0.0078 0.0088 0.0102
Loa Loa (eye worm) hypothetical protein 0.0108 0.0165 0.0163
Toxoplasma gondii transporter, cation channel family protein 0.0108 0.0165 0.1979
Loa Loa (eye worm) hypothetical protein 0.0108 0.0165 0.0163
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0052 0.0019 0.0028
Plasmodium falciparum apical membrane antigen 1 0.0308 0.068 1
Echinococcus multilocularis transfer RNA-Gly 0.0225 0.0465 0.0687
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0108 0.0166 0.0245
Echinococcus granulosus transient receptor potential cation channel 0.0108 0.0165 0.0244
Brugia malayi G protein-coupled receptor F59B2.13 0.0108 0.0166 0.0163
Schistosoma mansoni voltage-gated potassium channel 0.0116 0.0186 0.0247
Echinococcus granulosus g protein coupled receptor 0.0108 0.0166 0.0245
Schistosoma mansoni amine GPCR 0.0108 0.0166 0.0217
Echinococcus granulosus neuropeptide FF receptor 2 0.0108 0.0166 0.0245
Echinococcus granulosus potassium voltage gated channel subfamily A 0.2669 0.6776 1
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0225 0.0465 0.0463
Echinococcus multilocularis rhodopsin orphan GPCR 0.0108 0.0166 0.0245
Schistosoma mansoni two-pore calcium channel 0.0108 0.0165 0.0216
Toxoplasma gondii transporter, cation channel family protein 0.0108 0.0165 0.1979
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0108 0.0165 0.0244
Brugia malayi hypothetical protein 0.0108 0.0166 0.0163
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0108 0.0165 0.0163
Echinococcus multilocularis voltage gated potassium channel 0.0108 0.0165 0.0244
Echinococcus granulosus receptor type guanylyl cyclase 0.0055 0.0027 0.0039
Brugia malayi hypothetical protein 0.0108 0.0166 0.0163
Onchocerca volvulus 0.0108 0.0166 0.1582

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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