Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | FKBP5 protein | 0.0306 | 0.3022 | 1 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 | 0.0306 | 0.3022 | 1 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.0306 | 0.3022 | 1 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP4 | 0.0306 | 0.3022 | 0.3857 |
Onchocerca volvulus | 0.0042 | 0 | 0.5 | |
Trichomonas vaginalis | fk506-binding protein, putative | 0.0306 | 0.3022 | 1 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0727 | 0.7835 | 1 |
Trichomonas vaginalis | immunophilin, putative | 0.0306 | 0.3022 | 1 |
Schistosoma mansoni | immunophilin | 0.0306 | 0.3022 | 0.3857 |
Wolbachia endosymbiont of Brugia malayi | FKBP-type peptidylprolyl isomerase | 0.0042 | 0 | 0.5 |
Chlamydia trachomatis | peptidyl-prolyl cis-trans isomerase | 0.0652 | 0.6978 | 0.5 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, FKBP-type, putative | 0.0306 | 0.3022 | 1 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP1A | 0.0306 | 0.3022 | 0.3857 |
Leishmania major | peptidylprolyl isomerase-like protein | 0.0306 | 0.3022 | 1 |
Wolbachia endosymbiont of Brugia malayi | FKBP-type peptidylprolyl isomerase | 0.0042 | 0 | 0.5 |
Trypanosoma cruzi | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.0306 | 0.3022 | 1 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase, putative | 0.0306 | 0.3022 | 1 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, FKBP-type , putative | 0.0306 | 0.3022 | 1 |
Mycobacterium leprae | PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG | 0.0042 | 0 | 0.5 |
Trypanosoma brucei | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.0306 | 0.3022 | 1 |
Echinococcus multilocularis | peptidyl prolyl cis trans isomerase FKBP4 | 0.0306 | 0.3022 | 0.3857 |
Schistosoma mansoni | immunophilin | 0.0306 | 0.3022 | 0.3857 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0727 | 0.7835 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.2539 | 0.8404 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0727 | 0.7835 | 1 |
Echinococcus multilocularis | fk506 binding protein | 0.0306 | 0.3022 | 0.3857 |
Echinococcus multilocularis | peptidyl prolyl cis trans isomerase FKBP4 | 0.0264 | 0.2539 | 0.3241 |
Mycobacterium ulcerans | FK-506 binding protein, peptidyl-prolyl cis-trans isomerase | 0.0306 | 0.3022 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0126 | 0.0957 | 0.3166 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.0306 | 0.3022 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0126 | 0.0957 | 0.3166 |
Onchocerca volvulus | 0.0042 | 0 | 0.5 | |
Plasmodium vivax | 70 kDa peptidylprolyl isomerase, putative | 0.0306 | 0.3022 | 1 |
Trichomonas vaginalis | peptidylprolyl isomerase, putative | 0.0306 | 0.3022 | 1 |
Giardia lamblia | FKBP-type peptidyl-prolyl cis-trans isomerase | 0.0306 | 0.3022 | 1 |
Mycobacterium tuberculosis | Probable trigger factor (TF) protein Tig | 0.0042 | 0 | 0.5 |
Plasmodium falciparum | peptidyl-prolyl cis-trans isomerase FKBP35 | 0.0306 | 0.3022 | 1 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP4 | 0.0264 | 0.2539 | 0.3241 |
Trichomonas vaginalis | peptidylprolyl isomerase, putative | 0.0306 | 0.3022 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0126 | 0.0957 | 0.3166 |
Giardia lamblia | 70 kDa peptidylprolyl isomerase, putative | 0.0306 | 0.3022 | 1 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 | 0.0306 | 0.3022 | 1 |
Loa Loa (eye worm) | FKBP-type peptidyl-prolyl cis-trans isomerase-12 | 0.0306 | 0.3022 | 1 |
Toxoplasma gondii | peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein | 0.0652 | 0.6978 | 1 |
Schistosoma mansoni | immunophilin | 0.0264 | 0.2539 | 0.3241 |
Schistosoma mansoni | immunophilin FK506 binding protein FKBP12 | 0.0306 | 0.3022 | 0.3857 |
Trypanosoma cruzi | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.0306 | 0.3022 | 1 |
Leishmania major | fk506-binding protein 1-like protein | 0.0306 | 0.3022 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.