Detailed information for compound 1751888

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 534.363 | Formula: C16H9N4Na3O9S2
  • H donors: 4 H acceptors: 9 LogP: 0.69 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=c1c(/N=N/c2ccc(cc2)S(=O)(=O)[O-])c([nH]n1c1ccc(cc1)S(=O)(=O)[O-])C(=O)[O-].[Na+].[Na+].[Na+]
  • InChi: 1S/C16H12N4O9S2.3Na/c21-15-13(18-17-9-1-5-11(6-2-9)30(24,25)26)14(16(22)23)19-20(15)10-3-7-12(8-4-10)31(27,28)29;;;/h1-8,19H,(H,22,23)(H,24,25,26)(H,27,28,29);;;/q;3*+1/p-3/b18-17+;;;
  • InChiKey: ZLWLTDZLUVBSRJ-GLCFPVLVSA-K  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis neuropeptide Y receptor 0.0193 0.0538 0.0712
Onchocerca volvulus 0.0193 0.0538 0.5847
Schistosoma mansoni lamin 0.0055 0.0118 0.0209
Echinococcus multilocularis dna polymerase eta 0.002 0.0009 0.0007
Echinococcus granulosus tm gpcr rhodopsin 0.0193 0.0538 0.0979
Echinococcus multilocularis flap endonuclease 1 0.0027 0.003 0.0035
Echinococcus granulosus neuropeptide Y receptor 0.0193 0.0538 0.0979
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0193 0.0538 0.0712
Echinococcus multilocularis neuropeptide s receptor 0.0193 0.0538 0.0712
Schistosoma mansoni neuroligin 3 (S09 family) 0.0305 0.088 0.1606
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.004 0.0035
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0083 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.004 0.004
Brugia malayi hypothetical protein 0.0309 0.089 0.089
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0193 0.0538 0.0979
Echinococcus multilocularis acetylcholinesterase 0.1806 0.5457 0.7274
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Echinococcus granulosus lamin dm0 0.0055 0.0118 0.0209
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0046 0.0046
Brugia malayi Flap endonuclease-1 0.0027 0.003 0.003
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0009 0.0005
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0193 0.0538 0.0979
Schistosoma mansoni biogenic amine (5HT) receptor 0.0193 0.0538 0.0979
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0193 0.0538 0.0712
Echinococcus multilocularis sex peptide receptor 0.0193 0.0538 0.0712
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Schistosoma mansoni myosin xvIII 0.0193 0.0538 0.0979
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0193 0.0538 0.0979
Onchocerca volvulus 0.0193 0.0538 0.5847
Loa Loa (eye worm) hypothetical protein 0.0818 0.2445 0.2441
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0028 0.0023
Loa Loa (eye worm) hypothetical protein 0.0154 0.042 0.0416
Brugia malayi hypothetical protein 0.0073 0.0172 0.0172
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Echinococcus multilocularis g protein coupled receptor 0.0193 0.0538 0.0712
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0118 0.0118
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0021 0.5
Brugia malayi hypothetical protein 0.0193 0.0538 0.0538
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0042 0.005
Echinococcus granulosus g protein coupled receptor 0.0193 0.0538 0.0979
Loa Loa (eye worm) carboxylesterase 0.1806 0.5457 0.5455
Loa Loa (eye worm) hypothetical protein 0.0122 0.0323 0.0318
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0009 0.0005
Loa Loa (eye worm) melatonin receptor type 1A 0.0193 0.0538 0.0534
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0193 0.0538 0.0534
Schistosoma mansoni neuropeptide F-like receptor 0.0193 0.0538 0.0979
Brugia malayi Carboxylesterase family protein 0.0305 0.088 0.088
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0193 0.0538 0.0979
Echinococcus multilocularis rhodopsin orphan GPCR 0.0193 0.0538 0.0712
Onchocerca volvulus 0.0193 0.0538 0.5847
Brugia malayi hypothetical protein 0.0193 0.0538 0.0538
Echinococcus granulosus neuropeptide receptor 0.0193 0.0538 0.0979
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0305 0.088 1
Schistosoma mansoni BC026374 protein (S09 family) 0.0305 0.088 0.1606
Brugia malayi hypothetical protein 0.0193 0.0538 0.0538
Schistosoma mansoni caspase-7 (C14 family) 0.0092 0.0229 0.0412
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0305 0.088 0.1606
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0098 0.0171
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.0005
Loa Loa (eye worm) CYP4Cod1 0.0023 0.0021 0.0016
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0039 0.0063
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0098 0.0125
Echinococcus multilocularis caspase 2 0.0092 0.0229 0.0299
Brugia malayi G-protein coupled receptor 0.0193 0.0538 0.0538
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.0098 0.0655
Loa Loa (eye worm) G-protein coupled receptor 0.0193 0.0538 0.0534
Schistosoma mansoni neuropeptide receptor 0.0193 0.0538 0.0979
Schistosoma mansoni opsin-like receptor 0.0193 0.0538 0.0979
Leishmania major DNA polymerase kappa, putative 0.002 0.0009 0.0005
Entamoeba histolytica hypothetical protein 0.0073 0.0172 0.165
Giardia lamblia DNA repair protein RAD52 0.0343 0.0997 1
Echinococcus granulosus somatostatin receptor 0.0193 0.0538 0.0979
Echinococcus granulosus neuropeptide FF receptor 2 0.0193 0.0538 0.0979
Echinococcus granulosus peptide allatostatin:somatostatin 0.0193 0.0538 0.0979
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0042 1
Brugia malayi G protein-coupled receptor 0.0193 0.0538 0.0538
Echinococcus granulosus muscleblind protein 0.0154 0.042 0.0762
Entamoeba histolytica hypothetical protein 0.0098 0.0247 0.241
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0009 0.0005
Brugia malayi Tachykinin-like peptides receptor 99D 0.0193 0.0538 0.0538
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0009 0.0009
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0305 0.088 1
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0101 0.0256 0.0252
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.0005
Schistosoma mansoni biogenic amine (5HT) receptor 0.0818 0.2445 0.4476
Brugia malayi sulfakinin receptor protein 0.0193 0.0538 0.0538
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0098 0.0125
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0193 0.0538 0.0534
Loa Loa (eye worm) hypothetical protein 0.0092 0.0229 0.0225
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0305 0.088 1
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0009 0.0005
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0193 0.0538 0.0979
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0009 0.0005
Schistosoma mansoni hypothetical protein 0.0193 0.0538 0.0979
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0009 0.0007
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.003 0.6866
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Echinococcus multilocularis neuropeptide receptor A26 0.0193 0.0538 0.0712
Echinococcus granulosus BC026374 protein S09 family 0.0305 0.088 0.1606
Brugia malayi hypothetical protein 0.0193 0.0538 0.0538
Echinococcus multilocularis dna polymerase kappa 0.002 0.0009 0.0007
Schistosoma mansoni hypothetical protein 0.0069 0.0159 0.0284
Echinococcus multilocularis G protein coupled receptor 139 0.0193 0.0538 0.0712
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2476 0.75 1
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Echinococcus multilocularis neuroligin 0.0305 0.088 0.1168
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0193 0.0538 0.0538
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0021 0.5
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0193 0.0538 0.0534
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0073 0.0126
Brugia malayi Melatonin receptor type 1A 0.0193 0.0538 0.0538
Echinococcus granulosus caspase 2 0.0092 0.0229 0.0412
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0172 0.0224
Onchocerca volvulus 0.0193 0.0538 0.5847
Brugia malayi Muscleblind-like protein 0.0154 0.042 0.042
Schistosoma mansoni neuropeptide receptor 0.0193 0.0538 0.0979
Onchocerca volvulus 0.0193 0.0538 0.5847
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0193 0.0538 0.0979
Brugia malayi Serotonin receptor 0.0193 0.0538 0.0538
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0193 0.0538 0.0538
Schistosoma mansoni amine GPCR 0.0193 0.0538 0.0979
Loa Loa (eye worm) hypothetical protein 0.0055 0.0118 0.0114
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Loa Loa (eye worm) hypothetical protein 0.0305 0.088 0.0876
Echinococcus multilocularis rhodopsin orphan GPCR 0.0193 0.0538 0.0712
Loa Loa (eye worm) neuropeptide F receptor 0.0193 0.0538 0.0534
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0009 0.0009
Brugia malayi AKH receptor 0.0193 0.0538 0.0538
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.0005
Trypanosoma brucei cytochrome P450, putative 0.0023 0.0021 0.0016
Echinococcus granulosus caspase 8 0.0018 0.0004 0.00000000714
Brugia malayi jmjC domain containing protein 0.006 0.0132 0.0132
Echinococcus granulosus tm gpcr rhodopsin 0.0193 0.0538 0.0979
Echinococcus granulosus rhodopsin orphan GPCR 0.0193 0.0538 0.0979
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Schistosoma mansoni hypothetical protein 0.0074 0.0174 0.0311
Onchocerca volvulus 0.0193 0.0538 0.5847
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0193 0.0538 0.0712
Echinococcus granulosus biogenic amine 5HT receptor 0.0818 0.2445 0.4476
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0027 0.003 0.0026
Echinococcus granulosus lysine specific demethylase 5A 0.006 0.0132 0.0235
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0009 0.0057
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.003 0.0213
Onchocerca volvulus 0.0305 0.088 0.9878
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0009 0.0009
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0042 0.0069
Leishmania major cytochrome p450-like protein 0.0023 0.0021 0.0016
Echinococcus granulosus acetylcholinesterase 0.1806 0.5457 1
Echinococcus multilocularis para nitrobenzyl esterase 0.0305 0.088 0.1168
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0118 0.0152
Loa Loa (eye worm) hypothetical protein 0.0055 0.0118 0.0114
Entamoeba histolytica Flap nuclease, putative 0.0027 0.003 0.0213
Onchocerca volvulus 0.0193 0.0538 0.5847
Loa Loa (eye worm) hypothetical protein 0.0122 0.0323 0.0318
Echinococcus multilocularis BC026374 protein (S09 family) 0.0305 0.088 0.1168
Brugia malayi Cell death protein 3 precursor 0.0092 0.0229 0.0229
Echinococcus multilocularis fmrfamide receptor 0.0193 0.0538 0.0712
Brugia malayi Calcitonin receptor-like protein seb-1 0.0101 0.0256 0.0256
Brugia malayi Cytochrome P450 family protein 0.0023 0.0021 0.0021
Brugia malayi Cytochrome P450 family protein 0.0023 0.0021 0.0021
Echinococcus granulosus orexin receptor type 2 0.0193 0.0538 0.0979
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0021 0.0128
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0193 0.0538 0.0979
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0046 0.0077
Loa Loa (eye worm) carboxylesterase 0.0305 0.088 0.0876
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0132 0.0235
Loa Loa (eye worm) hypothetical protein 0.0616 0.1827 0.1824
Loa Loa (eye worm) hypothetical protein 0.3296 1 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0021 0.0016
Entamoeba histolytica hypothetical protein 0.0073 0.0172 0.165
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0021 0.0016
Onchocerca volvulus 0.0049 0.0098 0.0655
Brugia malayi ORL1-like opioid receptor 0.0193 0.0538 0.0538
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.003 0.6866
Schistosoma mansoni intermediate filament proteins 0.0055 0.0118 0.0209
Schistosoma mansoni opsin-like receptor 0.0193 0.0538 0.0979
Loa Loa (eye worm) hypothetical protein 0.0026 0.0028 0.0023
Echinococcus granulosus 7TM GPCR rhodopsin 0.0193 0.0538 0.0979
Echinococcus multilocularis geminin 0.034 0.0987 0.1311
Onchocerca volvulus 0.0309 0.089 1
Onchocerca volvulus 0.0193 0.0538 0.5847
Echinococcus granulosus rhodopsin orphan GPCR 0.0193 0.0538 0.0979
Brugia malayi hypothetical protein 0.0074 0.0174 0.0174
Schistosoma mansoni hypothetical protein 0.0032 0.0046 0.0077
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0042 0.005
Echinococcus granulosus serotonin receptor 0.0193 0.0538 0.0979
Echinococcus granulosus dro:myosuppressin receptor 0.0193 0.0538 0.0979
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0172 0.0308
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0042 0.0069
Brugia malayi G-protein coupled receptor 0.0193 0.0538 0.0538
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0028 0.8999
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0193 0.0538 0.0979
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Echinococcus multilocularis neuropeptide Y receptor 0.0193 0.0538 0.0712
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0046 0.0077
Onchocerca volvulus 0.0193 0.0538 0.5847
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0098 0.0171
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Schistosoma mansoni amine GPCR 0.0193 0.0538 0.0979
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0193 0.0538 0.0712
Echinococcus granulosus alpha 1A adrenergic receptor 0.0193 0.0538 0.0979
Brugia malayi hypothetical protein 0.0193 0.0538 0.0538
Echinococcus multilocularis rhodopsin orphan GPCR 0.0193 0.0538 0.0712
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.006 0.0132 0.0235
Brugia malayi putative neuropeptide receptor NPR1 0.0193 0.0538 0.0538
Echinococcus multilocularis rhodopsin orphan GPCR 0.0193 0.0538 0.0712
Echinococcus multilocularis microtubule associated protein 2 0.0689 0.2052 0.2731
Echinococcus multilocularis G-protein coupled receptor, putative 0.0193 0.0538 0.0712
Loa Loa (eye worm) hypothetical protein 0.0054 0.0115 0.0111
Echinococcus multilocularis lysine specific demethylase 5A 0.006 0.0132 0.0171
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0305 0.088 0.1606
Echinococcus granulosus neuropeptide Y receptor 0.0193 0.0538 0.0979
Onchocerca volvulus 0.0083 0.0203 0.1891
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0046 0.0042
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0037 0.0063 0.0058
Echinococcus granulosus biogenic amine 5HT receptor 0.0193 0.0538 0.0979
Echinococcus granulosus allatostatin A receptor 0.0193 0.0538 0.0979
Loa Loa (eye worm) neuropeptide F receptor 0.0193 0.0538 0.0534
Onchocerca volvulus Huntingtin homolog 0.0122 0.0323 0.3305
Schistosoma mansoni biogenic amine receptor 0.0193 0.0538 0.0979
Brugia malayi Dopamine receptor protein 1 0.0616 0.1827 0.1827
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0193 0.0538 0.0534
Echinococcus multilocularis caspase 8 0.0018 0.0004 0.0000000051935
Schistosoma mansoni alpha-1 adrenergic receptor 0.0193 0.0538 0.0979
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0192 0.0535 0.0707
Onchocerca volvulus 0.0305 0.088 0.9878
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0193 0.0538 0.0712
Onchocerca volvulus Huntingtin homolog 0.0122 0.0323 0.3305
Schistosoma mansoni hypothetical protein 0.034 0.0987 0.1803
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0343 0.0997 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0193 0.0538 0.0979
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0193 0.0538 0.0979
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0193 0.0538 0.5847
Schistosoma mansoni neuropeptide receptor 0.0193 0.0538 0.0979
Schistosoma mansoni acetylcholinesterase 0.0305 0.088 0.1606
Schistosoma mansoni flap endonuclease-1 0.0024 0.0023 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.0005
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0053 0.0048
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0023 0.0021 0.0129
Echinococcus granulosus rhodopsin orphan GPCR 0.0193 0.0538 0.0979
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0193 0.0538 0.0979
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0055 0.0579
Echinococcus multilocularis rhodopsin orphan GPCR 0.0193 0.0538 0.0712
Echinococcus multilocularis GPCR, family 2 0.0032 0.0046 0.0056
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0193 0.0538 0.0979
Loa Loa (eye worm) hypothetical protein 0.0026 0.0028 0.0023
Brugia malayi Serotonin receptor 0.0193 0.0538 0.0538
Loa Loa (eye worm) hypothetical protein 0.1685 0.5086 0.5084
Echinococcus granulosus dna polymerase kappa 0.002 0.0009 0.0009
Brugia malayi G protein-coupled receptor F59B2.13 0.0193 0.0538 0.0538
Echinococcus granulosus apoptotic protease activating factor 1 0.0074 0.0174 0.0311
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.003 0.0026
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0046 0.0056
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Schistosoma mansoni hypothetical protein 0.0032 0.0046 0.0077
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0193 0.0538 0.0979
Brugia malayi GnHR receptor homolog 0.0193 0.0538 0.0538
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0046 0.0056
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.006 0.0132 0.0171
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0042 0.0069
Schistosoma mansoni lamin 0.0055 0.0118 0.0209
Echinococcus granulosus fmrfamide receptor 0.0193 0.0538 0.0979
Echinococcus multilocularis serotonin receptor 0.0818 0.2445 0.3256
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.0005
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0028 0.0023
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.0309 0.0305
Loa Loa (eye worm) hypothetical protein 0.0305 0.088 0.0876
Loa Loa (eye worm) hypothetical protein 0.0083 0.0203 0.0198
Echinococcus multilocularis acetylcholinesterase 0.1806 0.5457 0.7274
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0018 0.0004 0.00000000714
Loa Loa (eye worm) hypothetical protein 0.0305 0.088 0.0876
Loa Loa (eye worm) hypothetical protein 0.0305 0.088 0.0876
Entamoeba histolytica hypothetical protein 0.0073 0.0172 0.165
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0193 0.0538 0.0979
Echinococcus multilocularis g-protein coupled receptor 0.0193 0.0538 0.0712
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0027 0.003 0.0026
Leishmania major C-8 sterol isomerase-like protein 0.3296 1 1
Brugia malayi mbt repeat family protein 0.0049 0.0098 0.0098
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0098 0.0171
Loa Loa (eye worm) hypothetical protein 0.0032 0.0046 0.0042
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0083 0.0203 0.0364
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0021 0.4266
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0118 0.0209
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.0005
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0193 0.0538 0.0979
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0118 0.0118
Loa Loa (eye worm) hypothetical protein 0.0305 0.088 0.0876
Brugia malayi follicle stimulating hormone receptor 0.0193 0.0538 0.0538
Echinococcus multilocularis serotonin receptor 0.0818 0.2445 0.3256
Schistosoma mansoni histamine h1 receptor 0.0193 0.0538 0.0979
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0021 0.5
Echinococcus multilocularis neuropeptide receptor 0.0193 0.0538 0.0712
Echinococcus multilocularis musashi 0.0055 0.0118 0.0152
Brugia malayi hypothetical protein 0.0193 0.0538 0.0538
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0021 0.4266
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0118 0.0114
Loa Loa (eye worm) hypothetical protein 0.0101 0.0256 0.0252
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0132 0.0128
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0009 0.0005
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0021 0.6214
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.0005
Echinococcus granulosus neuropeptide receptor 0.0193 0.0538 0.0979
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0193 0.0538 0.0712
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0073 0.0126
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0193 0.0538 0.0979
Echinococcus multilocularis neuropeptides capa receptor 0.0193 0.0538 0.0712
Echinococcus granulosus GPCR family 2 0.0032 0.0046 0.0077
Brugia malayi Carboxylesterase family protein 0.1806 0.5457 0.5457
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0005
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0118 0.0209
Schistosoma mansoni hypothetical protein 0.0073 0.0172 0.0308
Leishmania major DNA polymerase eta, putative 0.002 0.0009 0.0005
Brugia malayi Carboxylesterase family protein 0.0305 0.088 0.088
Echinococcus granulosus L aminoadipate semialdehyde 0.0083 0.0203 0.0364
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0305 0.088 0.1168
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0021 0.5
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0193 0.0538 0.0979
Loa Loa (eye worm) hypothetical protein 0.0305 0.088 0.0876
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0021 0.0016
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0037 0.0063 0.0078
Schistosoma mansoni amine GPCR 0.0193 0.0538 0.0979
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0098 0.0093
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Brugia malayi Dopamine receptor protein 2 0.0193 0.0538 0.0538
Echinococcus granulosus 7tm_1 domain containing protein 0.0193 0.0538 0.0979
Echinococcus multilocularis g protein coupled receptor 0.0193 0.0538 0.0712
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0009 0.0057
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0009 0.0005
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0098 0.0247 0.241
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0021 0.4266
Echinococcus multilocularis rhodopsin orphan GPCR 0.0193 0.0538 0.0712
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0009 0.0009
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0193 0.0538 0.0538
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0212 0.0597 0.0593
Loa Loa (eye worm) MBCTL1 0.0055 0.0118 0.0114
Echinococcus multilocularis neuropeptide receptor 0.0193 0.0538 0.0712
Brugia malayi MH2 domain containing protein 0.0118 0.0309 0.0309
Echinococcus multilocularis dro:myosuppressin receptor 0.0193 0.0538 0.0712
Onchocerca volvulus 0.0193 0.0538 0.5847
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0193 0.0538 0.0712
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Onchocerca volvulus 0.0193 0.0538 0.5847
Onchocerca volvulus 0.0305 0.088 0.9878
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0028 0.6179
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0193 0.0538 0.0979
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0118 0.0209
Echinococcus multilocularis carboxylesterase 5A 0.1806 0.5457 0.7274
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0193 0.0538 0.0979
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0118 0.0114
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0009 0.0005
Brugia malayi Carboxylesterase family protein 0.0305 0.088 0.088
Brugia malayi Cytochrome P450 family protein 0.0034 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Brugia malayi hypothetical protein 0.0122 0.0323 0.0323
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0098 0.0171
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0009 0.0005
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.1806 0.5457 1
Brugia malayi Carboxylesterase family protein 0.1806 0.5457 0.5457
Brugia malayi putative neuropeptide receptor 0.0193 0.0538 0.0538
Brugia malayi hypothetical protein 0.0193 0.0538 0.0538
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0018 0.0004 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.0005
Schistosoma mansoni gliotactin 0.0305 0.088 0.1606
Onchocerca volvulus 0.0193 0.0538 0.5847
Entamoeba histolytica hypothetical protein 0.0073 0.0172 0.165
Schistosoma mansoni hypothetical protein 0.0032 0.0046 0.0077
Echinococcus multilocularis rhodopsin orphan GPCR 0.0193 0.0538 0.0712
Echinococcus granulosus neuropeptides capa receptor 0.0193 0.0538 0.0979
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0193 0.0538 0.0534
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0021 0.0128
Schistosoma mansoni hypothetical protein 0.0193 0.0538 0.0979
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0101 0.0256 0.0256
Plasmodium vivax SET domain protein, putative 0.003 0.0042 1
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0021 0.0016
Loa Loa (eye worm) hypothetical protein 0.0154 0.042 0.0416
Entamoeba histolytica hypothetical protein 0.0023 0.0021 0.0113
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0305 0.088 0.1606
Echinococcus granulosus neuropeptide s receptor 0.0193 0.0538 0.0979
Onchocerca volvulus Cell death protein 3 homolog 0.0092 0.0229 0.2201
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.0309 0.0305
Leishmania major hypothetical protein, conserved 0.0026 0.0028 0.0023
Schistosoma mansoni hypothetical protein 0.034 0.0987 0.1803
Echinococcus multilocularis neuropeptides capa receptor 0.0193 0.0538 0.0712
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0193 0.0538 0.0979
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0159 0.0159
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0009 0.0005
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0193 0.0538 0.0979
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0042 0.0069
Brugia malayi hypothetical protein 0.0026 0.0028 0.0028
Echinococcus multilocularis g protein coupled receptor 0.0193 0.0538 0.0712
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0193 0.0538 0.0712
Echinococcus granulosus hypothetical protein 0.0193 0.0538 0.0979
Loa Loa (eye worm) hypothetical protein 0.0309 0.089 0.0886
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Echinococcus multilocularis lamin 0.0055 0.0118 0.0152
Schistosoma mansoni neuropeptide f receptor 76f 0.0193 0.0538 0.0979
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0037 0.0063 0.0063
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0193 0.0538 0.0538
Echinococcus granulosus acetylcholinesterase 0.1806 0.5457 1
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0046 0.0046
Echinococcus granulosus rhodopsin orphan GPCR 0.0193 0.0538 0.0979
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.0026
Onchocerca volvulus 0.0074 0.0174 0.1551
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0305 0.088 0.1606
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Schistosoma mansoni neuropeptide F-like receptor 0.0193 0.0538 0.0979
Brugia malayi neuropeptide F receptor 0.0193 0.0538 0.0538
Loa Loa (eye worm) hypothetical protein 0.1806 0.5457 0.5455
Loa Loa (eye worm) hypothetical protein 0.0049 0.0098 0.0093
Schistosoma mansoni biogenic amine receptor 0.0193 0.0538 0.0979
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0009 0.0005
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0021 0.0016
Loa Loa (eye worm) carboxylesterase 0.0305 0.088 0.0876
Schistosoma mansoni jumonji domain containing protein 0.006 0.0132 0.0235
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0193 0.0538 0.0538
Schistosoma mansoni DNA polymerase eta 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Trichomonas vaginalis set domain proteins, putative 0.0242 0.0687 0.7795
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0192 0.0535 0.0972
Echinococcus multilocularis orexin receptor type 2 0.0193 0.0538 0.0712
Echinococcus granulosus neuroligin 0.0305 0.088 0.1606
Loa Loa (eye worm) G-protein coupled receptor 0.0193 0.0538 0.0534
Brugia malayi hypothetical protein 0.0193 0.0538 0.0538
Brugia malayi Pre-SET motif family protein 0.003 0.0042 0.0042
Brugia malayi hypothetical protein 0.0193 0.0538 0.0538
Echinococcus granulosus microtubule associated protein 2 0.0689 0.2052 0.3755
Echinococcus multilocularis muscleblind protein 0.0154 0.042 0.0555
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0021 0.0016
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0037 0.0063 0.0107
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0193 0.0538 0.0712
Brugia malayi intermediate filament protein 0.0055 0.0118 0.0118
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0193 0.0538 0.0712
Echinococcus multilocularis L aminoadipate semialdehyde 0.0083 0.0203 0.0264
Echinococcus multilocularis fmrfamide receptor 0.0193 0.0538 0.0712
Echinococcus granulosus sex peptide receptor 0.0193 0.0538 0.0979
Brugia malayi Dopamine receptor 0.0193 0.0538 0.0538
Onchocerca volvulus 0.0193 0.0538 0.5847
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0193 0.0538 0.0712
Echinococcus granulosus g protein coupled receptor 0.0193 0.0538 0.0979
Onchocerca volvulus 0.0055 0.0118 0.0896
Echinococcus granulosus lamin 0.0055 0.0118 0.0209
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0193 0.0538 0.0979
Echinococcus multilocularis neuropeptide FF receptor 2 0.0193 0.0538 0.0712
Loa Loa (eye worm) hypothetical protein 0.0074 0.0174 0.0169
Brugia malayi hypothetical protein 0.0305 0.088 0.088
Onchocerca volvulus 0.0305 0.088 0.9878
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0193 0.0538 0.0712
Onchocerca volvulus 0.0242 0.0687 0.7601
Echinococcus granulosus g protein coupled receptor 0.0193 0.0538 0.0979
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Brugia malayi Pre-SET motif family protein 0.0212 0.0597 0.0597
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0193 0.0538 0.0979
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0193 0.0538 0.0979
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0028 0.8999
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0028 0.6179
Brugia malayi neuropeptide F receptor 0.0193 0.0538 0.0538
Onchocerca volvulus 0.0055 0.0118 0.0896
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0193 0.0538 0.0712
Mycobacterium tuberculosis Carboxylesterase LipT 0.0305 0.088 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0028 0.0023
Echinococcus multilocularis allatostatin A receptor 0.0193 0.0538 0.0712
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0172 0.0308
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.0005
Echinococcus granulosus para nitrobenzyl esterase 0.0305 0.088 0.1606
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0193 0.0538 0.0979
Schistosoma mansoni hypothetical protein 0.0032 0.0046 0.0077
Brugia malayi mbt repeat family protein 0.0049 0.0098 0.0098
Echinococcus granulosus rhodopsin orphan GPCR 0.0193 0.0538 0.0979
Mycobacterium ulcerans carboxylesterase, LipT 0.0305 0.088 1
Loa Loa (eye worm) hypothetical protein 0.1806 0.5457 0.5455
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Loa Loa (eye worm) hypothetical protein 0.0305 0.088 0.0876
Echinococcus granulosus carboxylesterase 5A 0.1806 0.5457 1
Echinococcus granulosus neuropeptides capa receptor 0.0193 0.0538 0.0979
Echinococcus granulosus neuropeptide receptor A26 0.0193 0.0538 0.0979
Onchocerca volvulus 0.0305 0.088 0.9878
Loa Loa (eye worm) acetylcholinesterase 1 0.1806 0.5457 0.5455
Loa Loa (eye worm) hypothetical protein 0.0032 0.0048 0.0043
Loa Loa (eye worm) hypothetical protein 0.0818 0.2445 0.2441
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0028 0.0023
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0031 0.0049
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.003 0.0297
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Echinococcus granulosus flap endonuclease 1 0.0027 0.003 0.0048
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0031 0.0035
Schistosoma mansoni growth hormone secretagogue receptor 0.0193 0.0538 0.0979
Trypanosoma cruzi C-8 sterol isomerase, putative 0.3296 1 1
Echinococcus granulosus tm gpcr rhodopsin 0.0193 0.0538 0.0979
Echinococcus granulosus intermediate filament protein 0.0055 0.0118 0.0209
Echinococcus granulosus rhodopsin orphan GPCR 0.0193 0.0538 0.0979
Echinococcus granulosus rhodopsin orphan GPCR 0.0193 0.0538 0.0979
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0193 0.0538 0.0979
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0021 0.0128
Brugia malayi jmjC domain containing protein 0.006 0.0132 0.0132
Schistosoma mansoni hypothetical protein 0.0193 0.0538 0.0979
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0193 0.0538 0.0979
Schistosoma mansoni hypothetical protein 0.0296 0.0852 0.1555
Brugia malayi Carboxylesterase family protein 0.0305 0.088 0.088
Onchocerca volvulus 0.0247 0.0702 0.7775
Trypanosoma brucei unspecified product 0.002 0.0009 0.0005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0193 0.0538 0.0712
Echinococcus multilocularis lamin dm0 0.0055 0.0118 0.0152
Echinococcus multilocularis apoptotic protease activating factor 1 0.0074 0.0174 0.0226
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0132 0.0235
Trichomonas vaginalis spcc417.12 protein, putative 0.0305 0.088 1
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0055 0.0579
Schistosoma mansoni hypothetical protein 0.0193 0.0538 0.0979
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0042 0.0069
Echinococcus granulosus geminin 0.034 0.0987 0.1803
Echinococcus granulosus tachykinin peptides receptor 99D 0.0193 0.0538 0.0979
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0009 0.0005
Schistosoma mansoni adenoreceptor 0.0193 0.0538 0.0979
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0027 0.003 0.0026
Plasmodium falciparum flap endonuclease 1 0.0027 0.003 1
Schistosoma mansoni microtubule-associated protein tau 0.0689 0.2052 0.3755
Brugia malayi hypothetical protein 0.0193 0.0538 0.0538
Loa Loa (eye worm) hypothetical protein 0.0069 0.0159 0.0155
Brugia malayi larval opioid receptor 0.0193 0.0538 0.0538
Onchocerca volvulus Neuropeptide F receptor homolog 0.0193 0.0538 0.5847
Onchocerca volvulus 0.0193 0.0538 0.5847
Echinococcus multilocularis somatostatin receptor 0.0193 0.0538 0.0712
Onchocerca volvulus 0.0193 0.0538 0.5847
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0193 0.0538 0.0979
Echinococcus granulosus dna polymerase eta 0.002 0.0009 0.0009
Brugia malayi RE15519p 0.0193 0.0538 0.0538
Echinococcus granulosus g-protein coupled receptor 0.0193 0.0538 0.0979
Trypanosoma brucei C-8 sterol isomerase, putative 0.3296 1 1
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0118 0.0152
Echinococcus granulosus G protein coupled receptor 139 0.0193 0.0538 0.0979
Schistosoma mansoni biogenic amine receptor 0.0193 0.0538 0.0979
Onchocerca volvulus 0.0193 0.0538 0.5847
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0193 0.0538 0.0712
Loa Loa (eye worm) hypothetical protein 0.0193 0.0538 0.0534
Schistosoma mansoni amine GPCR 0.0193 0.0538 0.0979
Echinococcus multilocularis muscleblind protein 1 0.0154 0.042 0.0555
Onchocerca volvulus 0.0193 0.0538 0.5847
Schistosoma mansoni neuropeptide receptor 0.0193 0.0538 0.0979
Loa Loa (eye worm) TYRA-2 protein 0.0193 0.0538 0.0534
Schistosoma mansoni opsin-like receptor 0.0193 0.0538 0.0979
Schistosoma mansoni amine GPCR 0.0535 0.158 0.2891
Loa Loa (eye worm) hypothetical protein 0.003 0.0042 0.0038
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0098 0.0171

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 25.5111 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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