Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | proteasome subunit beta type 1 | 0.007 | 0.1091 | 0.2253 |
Schistosoma mansoni | hypothetical protein | 0.0179 | 0.3395 | 1 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0053 | 0.0725 | 0.1497 |
Schistosoma mansoni | Mername-AA248 (C02 family) | 0.002 | 0.0021 | 0.0063 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0621 | 0.1829 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.047 | 0.0971 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0056 | 0.0776 | 0.2286 |
Echinococcus granulosus | calpain 5 | 0.002 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0039 | 0.0427 | 0.0882 |
Echinococcus multilocularis | calpain 7 (C02 family) | 0.002 | 0.0021 | 0.0021 |
Echinococcus multilocularis | hypothetical protein | 0.002 | 0.0021 | 0.0021 |
Trypanosoma brucei | proteasome subunit beta type-5, putative | 0.0157 | 0.2942 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.047 | 0.1384 |
Echinococcus multilocularis | calpain A | 0.0056 | 0.0776 | 0.0776 |
Leishmania major | proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative | 0.007 | 0.1091 | 0.3661 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0247 | 0.4842 | 1 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.0056 | 0.0776 | 0.0776 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0157 | 0.2942 | 1 |
Echinococcus multilocularis | calpain | 0.002 | 0.0021 | 0.0021 |
Brugia malayi | calpain family protein 1 | 0.0053 | 0.0725 | 0.1497 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0875 | 0.1807 |
Schistosoma mansoni | proteasome subunit beta 1 (T01 family) | 0.007 | 0.1091 | 0.3213 |
Echinococcus multilocularis | calpain 5 | 0.002 | 0.0021 | 0.0021 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0489 | 1 | 1 |
Trypanosoma brucei | proteasome beta 6 subunit | 0.007 | 0.1091 | 0.3661 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0621 | 0.1829 |
Mycobacterium leprae | proteasome (beta subunit) PrcB | 0.0157 | 0.2942 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0621 | 0.0621 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.006 | 0.0875 | 0.1807 |
Brugia malayi | proteasome subunit beta type 1 | 0.007 | 0.1091 | 0.2253 |
Schistosoma mansoni | proteasome catalytic subunit 3 (T01 family) | 0.0157 | 0.2942 | 0.8668 |
Schistosoma mansoni | calpain-7 (C02 family) | 0.002 | 0.0021 | 0.0063 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0041 | 0.047 | 0.0971 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0427 | 0.0882 |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.0056 | 0.0776 | 0.0776 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0157 | 0.2942 | 0.6077 |
Brugia malayi | Proteasome A-type and B-type family protein | 0.0157 | 0.2942 | 0.6077 |
Loa Loa (eye worm) | calpain | 0.002 | 0.0021 | 0.0044 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.007 | 0.1091 | 0.1091 |
Leishmania major | proteasome beta 5 subunit, putative | 0.0157 | 0.2942 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0621 | 0.0621 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0157 | 0.2942 | 1 |
Echinococcus granulosus | proteasome prosome macropain | 0.0157 | 0.2942 | 0.2942 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.007 | 0.1091 | 0.1091 |
Schistosoma mansoni | hypothetical protein | 0.0179 | 0.3395 | 1 |
Schistosoma mansoni | calpain C (C02 family) | 0.002 | 0.0021 | 0.0063 |
Plasmodium vivax | proteasome subunit beta type-5, putative | 0.0157 | 0.2942 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0621 | 0.1829 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0489 | 1 | 1 |
Giardia lamblia | Proteasome subunit beta type 5 precursor | 0.0157 | 0.2942 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0621 | 0.0621 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0053 | 0.0725 | 0.2136 |
Schistosoma mansoni | calpain-7 (C02 family) | 0.002 | 0.0021 | 0.0063 |
Echinococcus granulosus | geminin | 0.0179 | 0.3395 | 0.3395 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0725 | 0.1497 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.006 | 0.0875 | 0.1807 |
Echinococcus granulosus | calpain 7 C02 family | 0.002 | 0.0021 | 0.0021 |
Toxoplasma gondii | proteasome subunit beta type, putative | 0.0157 | 0.2942 | 1 |
Mycobacterium ulcerans | proteasome PrcB | 0.0157 | 0.2942 | 0.5 |
Mycobacterium tuberculosis | Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. | 0.0157 | 0.2942 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.0621 | 0.1282 |
Onchocerca volvulus | 0.0033 | 0.0299 | 0.5 | |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.0621 | 0.1282 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.006 | 0.0875 | 0.1807 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0489 | 1 | 1 |
Echinococcus multilocularis | geminin | 0.0179 | 0.3395 | 0.3395 |
Schistosoma mansoni | calpain (C02 family) | 0.002 | 0.0021 | 0.0063 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0299 | 0.0617 |
Echinococcus multilocularis | calpain family protein 1, d | 0.0039 | 0.0427 | 0.0427 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.007 | 0.1091 | 0.3661 |
Entamoeba histolytica | proteasome subunit beta type 5 precursor, putative | 0.0157 | 0.2942 | 1 |
Echinococcus granulosus | calpain A | 0.0056 | 0.0776 | 0.0776 |
Brugia malayi | follicle stimulating hormone receptor | 0.0247 | 0.4842 | 1 |
Echinococcus multilocularis | proteasome (prosome, macropain) | 0.0157 | 0.2942 | 0.2942 |
Plasmodium vivax | proteasome subunit beta type-1, putative | 0.007 | 0.1091 | 0.3661 |
Plasmodium falciparum | proteasome subunit beta type-5 | 0.0157 | 0.2942 | 1 |
Echinococcus granulosus | calpain A | 0.002 | 0.0021 | 0.0021 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0157 | 0.2942 | 1 |
Brugia malayi | calpain 7 | 0.002 | 0.0021 | 0.0044 |
Echinococcus granulosus | calpain | 0.002 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0597 | 0.1233 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0621 | 0.0621 |
Brugia malayi | calpain family protein 1 | 0.0053 | 0.0725 | 0.1497 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0056 | 0.0776 | 0.2286 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.007 | 0.1091 | 0.3661 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.