Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0814 | 1 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0814 | 1 | 1 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0814 | 1 | 1 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0814 | 1 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0042 | 0 | 0.5 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0814 | 1 | 1 |
Trypanosoma brucei | protein kinase, putative | 0.0814 | 1 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0042 | 0 | 0.5 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0814 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0814 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0814 | 1 | 1 |
Mycobacterium leprae | Probable lipase LipE | 0.0042 | 0 | 0.5 |
Mycobacterium ulcerans | beta-lactamase | 0.0042 | 0 | 0.5 |
Onchocerca volvulus | 0.0042 | 0 | 0.5 | |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0814 | 1 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0814 | 1 | 1 |
Onchocerca volvulus | 0.0042 | 0 | 0.5 | |
Trichomonas vaginalis | CMGC family protein kinase | 0.0814 | 1 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.0042 | 0 | 0.5 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0814 | 1 | 1 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0814 | 1 | 1 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0814 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0814 | 1 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0814 | 1 | 1 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0814 | 1 | 0.5 |
Onchocerca volvulus | 0.0042 | 0 | 0.5 | |
Mycobacterium ulcerans | hypothetical protein | 0.0042 | 0 | 0.5 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.027 | 0.2945 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0814 | 1 | 1 |
Mycobacterium ulcerans | lipase LipD | 0.0042 | 0 | 0.5 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0042 | 0 | 0.5 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0814 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.