Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0085 | 0 | 0.5 | |
Onchocerca volvulus | Dual oxidase homolog | 0.0085 | 0 | 0.5 |
Onchocerca volvulus | 0.0085 | 0 | 0.5 | |
Onchocerca volvulus | Peroxidase homolog | 0.0085 | 0 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0135 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0135 | 1 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0085 | 0 | 0.5 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0135 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0135 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0135 | 1 | 0.5 |
Onchocerca volvulus | Peroxidasin homolog | 0.0085 | 0 | 0.5 |
Echinococcus multilocularis | cathepsin b | 0.0135 | 1 | 1 |
Onchocerca volvulus | 0.0085 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 1 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0085 | 0 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0135 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0135 | 1 | 1 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0085 | 0 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0135 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.