Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Chorion peroxidase homolog | 0.0043 | 0.2205 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0043 | 0.2205 | 0.2518 |
Echinococcus multilocularis | muscleblind protein | 0.0148 | 0.8756 | 0.8756 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0138 | 0.8166 | 0.8166 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 0.8166 | 0.9327 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.2331 | 0.2331 |
Onchocerca volvulus | Peroxidase homolog | 0.0043 | 0.2205 | 0.5 |
Brugia malayi | hypothetical protein | 0.0043 | 0.2205 | 0.2518 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.2331 | 0.2331 |
Brugia malayi | Blistered cuticle protein 3 | 0.0043 | 0.2205 | 0.2518 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.2205 | 0.2518 |
Echinococcus multilocularis | peroxidasin | 0.0043 | 0.2205 | 0.2205 |
Giardia lamblia | Cathepsin B precursor | 0.0046 | 0.2357 | 0.5 |
Schistosoma mansoni | peroxidasin | 0.0043 | 0.2205 | 0.2205 |
Schistosoma mansoni | peroxidasin | 0.0043 | 0.2205 | 0.2205 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.2331 | 0.2331 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.8756 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0138 | 0.8166 | 0.8166 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0118 | 0.6896 | 0.7876 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0138 | 0.8166 | 0.8166 |
Giardia lamblia | Cathepsin B precursor | 0.0046 | 0.2357 | 0.5 |
Echinococcus multilocularis | geminin | 0.0167 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.2205 | 0.2518 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.2205 | 0.2518 |
Loa Loa (eye worm) | cathepsin B | 0.0046 | 0.2357 | 0.2692 |
Echinococcus multilocularis | cathepsin b | 0.0138 | 0.8166 | 0.8166 |
Echinococcus granulosus | cathepsin b | 0.0138 | 0.8166 | 0.8166 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.2205 | 0.2518 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.2205 | 0.2518 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.2205 | 0.2518 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0138 | 0.8166 | 0.9327 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.2205 | 0.2518 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0046 | 0.2357 | 0.5 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0043 | 0.2205 | 0.2518 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0043 | 0.2205 | 0.2518 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0046 | 0.2357 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.2205 | 0.2518 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0046 | 0.2357 | 0.2357 |
Brugia malayi | Muscleblind-like protein | 0.0148 | 0.8756 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.2205 | 0.2518 |
Onchocerca volvulus | 0.0043 | 0.2205 | 0.5 | |
Onchocerca volvulus | 0.0043 | 0.2205 | 0.5 | |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0138 | 0.8166 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0043 | 0.2205 | 0.5 |
Echinococcus granulosus | cathepsin b | 0.0138 | 0.8166 | 0.8166 |
Echinococcus multilocularis | cathepsin b | 0.0138 | 0.8166 | 0.8166 |
Brugia malayi | Animal haem peroxidase family protein | 0.0043 | 0.2205 | 0.2518 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.2205 | 0.2518 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.8756 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.2205 | 0.2518 |
Onchocerca volvulus | Peroxidasin homolog | 0.0043 | 0.2205 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0043 | 0.2205 | 0.2518 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.2205 | 0.2518 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0043 | 0.2205 | 0.2518 |
Echinococcus granulosus | peroxidasin | 0.0043 | 0.2205 | 0.2205 |
Echinococcus granulosus | muscleblind protein | 0.0148 | 0.8756 | 0.8756 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.2331 | 0.2663 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0148 | 0.8756 | 0.8756 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.2331 | 0.2331 |
Toxoplasma gondii | cathepsin B | 0.0046 | 0.2357 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.2331 | 0.2331 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0138 | 0.8166 | 0.8166 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0043 | 0.2205 | 0.2518 |
Onchocerca volvulus | 0.0043 | 0.2205 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.2205 | 0.2518 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.2205 | 0.2518 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0043 | 0.2205 | 0.2518 |
Brugia malayi | Animal haem peroxidase family protein | 0.0043 | 0.2205 | 0.2518 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.2331 | 0.2331 |
Onchocerca volvulus | Peroxidase homolog | 0.0043 | 0.2205 | 0.5 |
Brugia malayi | MH2 domain containing protein | 0.0118 | 0.6896 | 0.7876 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0043 | 0.2205 | 0.2518 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.2331 | 0.2331 |
Giardia lamblia | Cathepsin B precursor | 0.0046 | 0.2357 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.2331 | 0.2663 |
Brugia malayi | Peroxidasin | 0.0043 | 0.2205 | 0.2518 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0118 | 0.6896 | 0.7876 |
Onchocerca volvulus | Dual oxidase homolog | 0.0043 | 0.2205 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0046 | 0.2357 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.