Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | acetylcholinesterase | 0.013 | 0.1427 | 0.1427 |
Brugia malayi | Carboxylesterase family protein | 0.013 | 0.1427 | 0.1427 |
Echinococcus granulosus | neuroligin | 0.013 | 0.1427 | 0.1427 |
Onchocerca volvulus | 0.013 | 0.1427 | 1 | |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.013 | 0.1427 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.1427 | 0.1427 |
Loa Loa (eye worm) | carboxylesterase | 0.013 | 0.1427 | 0.1427 |
Echinococcus granulosus | plexin a4 | 0.0066 | 0.0579 | 0.0579 |
Schistosoma mansoni | plexin | 0.0056 | 0.044 | 0.044 |
Loa Loa (eye worm) | hypothetical protein | 0.0767 | 1 | 1 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.013 | 0.1427 | 0.1427 |
Loa Loa (eye worm) | carboxylesterase | 0.0767 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0767 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.044 | 0.044 |
Schistosoma mansoni | gliotactin | 0.013 | 0.1427 | 0.1427 |
Brugia malayi | plexin A | 0.0066 | 0.0579 | 0.0579 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.1427 | 0.1427 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.013 | 0.1427 | 0.1427 |
Loa Loa (eye worm) | carboxylesterase | 0.013 | 0.1427 | 0.1427 |
Echinococcus granulosus | acetylcholinesterase | 0.0767 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.013 | 0.1427 | 0.1427 |
Brugia malayi | Carboxylesterase family protein | 0.013 | 0.1427 | 0.1427 |
Brugia malayi | hypothetical protein | 0.013 | 0.1427 | 0.1427 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0767 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.1427 | 0.1427 |
Onchocerca volvulus | 0.013 | 0.1427 | 1 | |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.013 | 0.1427 | 0.1427 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.013 | 0.1427 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0124 | 0.0124 |
Echinococcus multilocularis | neuroligin | 0.013 | 0.1427 | 0.1427 |
Onchocerca volvulus | 0.0056 | 0.044 | 0.3085 | |
Onchocerca volvulus | 0.013 | 0.1427 | 1 | |
Echinococcus granulosus | para nitrobenzyl esterase | 0.013 | 0.1427 | 0.1427 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0124 | 0.0124 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.1427 | 0.1427 |
Brugia malayi | Carboxylesterase family protein | 0.0767 | 1 | 1 |
Echinococcus granulosus | BC026374 protein S09 family | 0.013 | 0.1427 | 0.1427 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.013 | 0.1427 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.1427 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.1427 | 0.1427 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.013 | 0.1427 | 0.5 |
Schistosoma mansoni | plexin | 0.0033 | 0.0124 | 0.0124 |
Loa Loa (eye worm) | plexin A | 0.0066 | 0.0579 | 0.0579 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.013 | 0.1427 | 0.1427 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.013 | 0.1427 | 0.5 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.013 | 0.1427 | 0.5 |
Onchocerca volvulus | 0.013 | 0.1427 | 1 | |
Echinococcus granulosus | carboxylesterase 5A | 0.0767 | 1 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.013 | 0.1427 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.013 | 0.1427 | 0.1427 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0767 | 1 | 1 |
Onchocerca volvulus | 0.013 | 0.1427 | 1 | |
Brugia malayi | Plexin repeat family protein | 0.0056 | 0.044 | 0.044 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0767 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.1427 | 0.1427 |
Echinococcus multilocularis | plexin a4 | 0.0066 | 0.0579 | 0.0579 |
Brugia malayi | Carboxylesterase family protein | 0.013 | 0.1427 | 0.1427 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.013 | 0.1427 | 0.1427 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.013 | 0.1427 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0767 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0767 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0767 | 1 | 1 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.013 | 0.1427 | 0.1427 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.