Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0076 | 0.1089 | 1 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0076 | 0.1089 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0076 | 0.1089 | 0.1089 |
Onchocerca volvulus | 0.0076 | 0.1089 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.1089 | 0.1089 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0451 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0076 | 0.1089 | 0.1089 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0076 | 0.1089 | 0.5 |
Onchocerca volvulus | 0.0076 | 0.1089 | 1 | |
Echinococcus multilocularis | carboxylesterase 5A | 0.0451 | 1 | 1 |
Echinococcus granulosus | plexin a4 | 0.0086 | 0.1323 | 0.1323 |
Onchocerca volvulus | 0.0073 | 0.1006 | 0.9238 | |
Echinococcus granulosus | acetylcholinesterase | 0.0451 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0451 | 1 | 1 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0076 | 0.1089 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0451 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0076 | 0.1089 | 0.1089 |
Brugia malayi | Carboxylesterase family protein | 0.0451 | 1 | 1 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0076 | 0.1089 | 0.1089 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.1089 | 0.1089 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0076 | 0.1089 | 0.1089 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.1089 | 0.1089 |
Loa Loa (eye worm) | hypothetical protein | 0.0451 | 1 | 1 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0076 | 0.1089 | 0.1089 |
Brugia malayi | plexin A | 0.0086 | 0.1323 | 0.1323 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0076 | 0.1089 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0076 | 0.1089 | 0.1089 |
Schistosoma mansoni | plexin | 0.0042 | 0.0284 | 0.0284 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0076 | 0.1089 | 0.1089 |
Schistosoma mansoni | acetylcholinesterase | 0.0076 | 0.1089 | 0.1089 |
Echinococcus multilocularis | acetylcholinesterase | 0.0451 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.1089 | 0.1089 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0076 | 0.1089 | 0.1089 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0076 | 0.1089 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0451 | 1 | 1 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0076 | 0.1089 | 0.1089 |
Brugia malayi | Carboxylesterase family protein | 0.0076 | 0.1089 | 0.1089 |
Onchocerca volvulus | 0.0076 | 0.1089 | 1 | |
Onchocerca volvulus | 0.0076 | 0.1089 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.1089 | 0.1089 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0076 | 0.1089 | 0.1089 |
Schistosoma mansoni | plexin | 0.0073 | 0.1006 | 0.1006 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0284 | 0.0284 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0284 | 0.0284 |
Echinococcus multilocularis | neuroligin | 0.0076 | 0.1089 | 0.1089 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0076 | 0.1089 | 0.1089 |
Loa Loa (eye worm) | carboxylesterase | 0.0076 | 0.1089 | 0.1089 |
Schistosoma mansoni | gliotactin | 0.0076 | 0.1089 | 0.1089 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.1089 | 0.1089 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0076 | 0.1089 | 0.1089 |
Echinococcus multilocularis | plexin a4 | 0.0086 | 0.1323 | 0.1323 |
Loa Loa (eye worm) | plexin A | 0.0086 | 0.1323 | 0.1323 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0076 | 0.1089 | 0.5 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0076 | 0.1089 | 0.1089 |
Echinococcus multilocularis | acetylcholinesterase | 0.0451 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.1006 | 0.1006 |
Brugia malayi | hypothetical protein | 0.0076 | 0.1089 | 0.1089 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.1089 | 0.1089 |
Echinococcus granulosus | neuroligin | 0.0076 | 0.1089 | 0.1089 |
Brugia malayi | Plexin repeat family protein | 0.0073 | 0.1006 | 0.1006 |
Brugia malayi | Carboxylesterase family protein | 0.0076 | 0.1089 | 0.1089 |
Loa Loa (eye worm) | carboxylesterase | 0.0451 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0451 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.